Life Sciences

Papers
(The median citation count of Life Sciences is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Metacaspase (Pf MCA-1) as antimalarial drug target: An in silico approach and their biological validation307
4-Methylumbelliferone induces antitumor effects independently of hyaluronan synthesis inhibition in human acute leukemia cell lines302
Insights into the development of insulin-producing cells: Precursors correlated involvement of microRNA panels277
Ergosterol promotes neurite outgrowth, inhibits amyloid-beta synthesis, and extends longevity: In vitro neuroblastoma and in vivo Caenorhabditis elegans evidence197
Behavioural disruption in diabetic mice: Neurobiological correlates and influences of dietary α-linolenic acid186
The role of endoplasmic reticulum aminopeptidases in type 1 diabetes mellitus179
Skp2-mediated Zeb1 expression facilitates cancer migration by a ubiquitination-independent pathway161
Rhein ameliorates septic lung injury and intervenes in macrophage metabolic reprogramming in the inflammatory state by Sirtuin 1150
Targeting GAS6/AXL signaling improves the response to immunotherapy by restoring the anti-immunogenic tumor microenvironment in gastric cancer142
Indole-3-carbinol induces apoptosis-like death in Escherichia coli on different contribution of respective reactive oxygen species133
Augmented nephroprotective effect of liraglutide and rabeprazole via inhibition of OCT2 transporter in cisplatin-induced nephrotoxicity in rats132
Ablation of Brg1 in fibroblast/myofibroblast lineages attenuates renal fibrosis in mice with diabetic nephropathy127
The combination of mesenchymal stem cell- and hepatocyte-derived exosomes, along with imipenem, ameliorates inflammatory responses and liver damage in a sepsis mouse model126
Cross-species gene expression patterns of purinergic signaling in the human and mouse trigeminal ganglion124
Exploring Lin28 proteins: Unravelling structure and functions with emphasis on nervous system malignancies121
Coadministration of olanzapine causes minor impacts on the diabetogenic outcomes induced by dexamethasone treatment in rats119
The N6-methyladenosine modification in pathologic angiogenesis119
Ivabradine restores tonic cardiovascular autonomic control and reduces tachycardia, hypertension and left ventricular inflammation in post-weaning protein malnourished rats118
Regulation of metabolism by circadian rhythms: Support from time-restricted eating, intestinal microbiota & omics analysis105
Cigarette smoking-related OLC1 overexpression associated with poor prognosis in bladder urothelial carcinoma87
Exercise training and probiotic supplementation effects on skeletal muscle apoptosis prevention in type-Ι diabetic rats86
Pancreastatin inhibitor PSTi8 prevents free fatty acid-induced oxidative stress and insulin resistance by modulating JNK pathway: In vitro and in vivo findings85
The proteomic landscape of ovarian cancer cells in response to melatonin85
Physical health, behavioral and emotional functioning in children of gulf war veterans84
The inhibition of autophagy by spautin boosts the anticancer activity of fingolimod in multidrug-resistant hepatocellular carcinoma84
Optimal intervention time of ADSCs for hepatic ischemia-reperfusion combined with partial resection injury in rats84
Renal protective effects and mechanisms of the angiotensin receptor-neprilysin inhibitor LCZ696 in mice with cardiorenal syndrome84
Transcranial alternating current stimulation inhibits ferroptosis and promotes functional recovery in spinal cord injury via the cGMP-PKG signalling pathway82
Emerging therapeutic landscape: Incretin agonists in chronic kidney disease management81
Mitochondrial transfer in the progression and treatment of cardiac disease81
Gulf War Illness Clinical Trials and Interventions Consortium (GWICTIC): A collaborative research infrastructure for intervention and implementation80
The role of exosomes in the molecular mechanisms of metastasis: Focusing on EMT and cancer stem cells80
Antioxidant therapy reverses sympathetic dysfunction, oxidative stress, and hypertension in male hyperadipose rats79
The anxiolytic sertraline reduces the impact of psychological stress on bladder function in mice78
The C C motif chemokine ligand 11 contributes to alcoholic liver disease74
Carboxyaminotriazole: A bone savior in collagen-induced arthritis—Halting osteoclastogenesis via interleukin-1β downregulation73
Characterizing COPD phenotypes with a targeted signaling lipids metabolomics approach71
Altering phosphorylation of dystrophin S3059 to attenuate cancer cachexia70
Editorial Board68
Hyperglycemia influences the cell proliferation and death of the rat endocrine pancreas in the neonatal period68
The dynamicity of mutant KRAS β2 strand modulates its downstream activation and predicts anticancer KRAS inhibition67
The combined therapy of mesenchymal stem cell transplantation and resveratrol for diabetes: Future applications and challenges67
Human gestational diabetes mellitus–derived exosomes impair glucose homeostasis in pregnant mice and stimulate functional maturation of offspring-islets64
The chromatin remodeling protein BRG1 mediates Ang II induced pro-fibrogenic response in renal fibroblasts64
Retraction notice to “Inhibition of CD73 using folate targeted nanoparticles carrying anti-CD73 siRNA potentiates anticancer efficacy of Dinaciclib” [Life Sci. 259 (2020) 118150]61
Environmental bacteria as triggers to brain disease: Possible mechanisms of toxicity and associated human risk61
Unleashing the pathological imprinting of cancer in autoimmunity: Is ZEB1 the answer?60
Combined effects of high fat diet and exercise on autophagy in white adipose tissue of mice60
Progesterone signaling in uterine fibroids: Molecular mechanisms and therapeutic opportunities59
Sulforaphane regulates Nrf2-mediated antioxidant activity and downregulates TGF-β1/Smad pathways to prevent radiation-induced muscle fibrosis58
Integrin αvβ3 and disulfide bonds play important roles in NGR-retargeted adenovirus transduction efficiency57
Evidence-based hormonal, mutational, and endocrine-disrupting chemical-induced zebrafish as an alternative model to study PCOS condition similar to mammalian PCOS model57
6-NitroDopamine is an endogenous modulator of rat heart chronotropism57
Liraglutide attenuates intestinal ischemia/reperfusion injury via NF-κB and PI3K/Akt pathways in mice56
Myeloid derived suppressor cells and innate immune system interaction in tumor microenvironment56
Mebendazole; from an anti-parasitic drug to a promising candidate for drug repurposing in colorectal cancer55
γ-Aminobutyric acid promotes the inhibition of hair growth induced by chronic restraint stress55
Targeting pyruvate kinase muscle isoform 2 (PKM2) in cancer: What do we know so far?55
Role of histone deacetylase Sirt3 in the development and regression of atherosclerosis54
Melatonin: A potential protective multifaceted force for sepsis-induced cardiomyopathy54
Metabolomics profiling and chemoresistance mechanisms in ovarian cancer cell lines: Implications for targeting glutathione pathway54
In vitro assessment of anti-fibrotic drug activity does not predict in vivo efficacy in murine models of Duchenne muscular dystrophy53
Upregulation of miR-222-3p alleviates the symptom of aortic dissection through targeting STAT353
Dysregulated pancreatic lipid phenotype, inflammation and cellular injury in a chronic ethanol feeding model of hepatic alcohol dehydrogenase-deficient deer mice53
Protective role of ellagic acid and taurine against fluoxetine induced hepatotoxic effects on biochemical and oxidative stress parameters, histopathological changes, and gene expressions of IL-1β, NF-53
Fluid shear stress facilitates prostate cancer metastasis through Piezo1-Src-YAP axis53
PEG-4000 formed polymeric nanoparticles loaded with cetuximab downregulate p21 & stathmin-1 gene expression in cancer cell lines53
Autophagy deficiency exacerbated hypoxia-reoxygenation induced inflammation and cell death via a mitochondrial DNA/STING/IRF3 pathway51
High fat diet exacerbates long-term metabolic, neuropathological, and behavioral derangements in an experimental mouse model of traumatic brain injury51
Suppression of PCSK9/NF-kB-dependent pathways by acetate ameliorates cardiac inflammation in a rat model of polycystic ovarian syndrome51
Novel decorated nanostructured lipid carrier for simultaneous active targeting of three anti-cancer agents51
Targeting HMG-CoA synthase 2 suppresses tamoxifen-resistant breast cancer growth by augmenting mitochondrial oxidative stress-mediated cell death51
Gold nanoparticles show potential in vitro antiviral and anticancer activity51
TRIM21 ubiquitylates GPX4 and promotes ferroptosis to aggravate ischemia/reperfusion-induced acute kidney injury50
Reactive oxygen species: Role in carcinogenesis, cancer cell signaling and tumor progression50
Photothermal therapy-mediated autophagy in breast cancer treatment: Progress and trends50
Spontaneous and familial models of Alzheimer's disease: Challenges and advances in preclinical research50
GALNT2 promotes cell proliferation, migration, and invasion by activating the Notch/Hes1-PTEN-PI3K/Akt signaling pathway in lung adenocarcinoma50
Effect of folate-targeted Erlotinib loaded human serum albumin nanoparticles on tumor size and survival rate in a rat model of glioblastoma50
Carvacrol enhances anti-tumor activity and mitigates cardiotoxicity of sorafenib in thioacetamide-induced hepatocellular carcinoma model through inhibiting TRPM750
Lacto-N-fucopentaose-III ameliorates acute and persisting hippocampal synaptic plasticity and transmission deficits in a Gulf War Illness mouse model49
Hesperidin attenuates hepatic lipid accumulation in mice fed high-fat diet and oleic acid induced HepG2 via AMPK activation49
Application of f-FeNC@GOx cascade enzyme nanomaterials in the healing of infected wounds48
Lung cancer vaccination from concept to reality: A critical review of clinical trials and latest advances47
Preclinical metabolic characterization of mefunidone, a novel anti-renal fibrosis drug47
MiR-375: A novel multifunctional regulator47
Dehydroepiandrosterone activates the GPER-mediated AMPK signaling pathway to alleviate the oxidative stress and inflammatory response in laying hens fed with high-energy and low-protein diets47
Repurposing therapeutics for malignant pleural mesothelioma (MPM) – Updates on clinical translations and future outlook47
Chlorogenic acid, quercetin, coenzyme Q10 and silymarin modulate Keap1-Nrf2/heme oxygenase-1 signaling in thioacetamide-induced acute liver toxicity47
Ex vivo Akt inhibition reverses castration induced internal pudendal artery and penile endothelial dysfunction46
A detailed insight into macrophages' role in shaping lung carcinogenesis46
Understanding stem cells and its pivotal role in regenerative medicine46
The impact of hypoxia on immune state in cancer46
Editorial Board46
Copper homeostasis and cuproptosis in mitochondria46
Effects of apolipoprotein E on regulating insulin sensitivity via regulating insulin receptor signalosome in caveolae45
Depot- and diabetes-specific differences in norepinephrine-mediated adipose tissue angiogenesis, vascular tone, collagen deposition and morphology in obesity45
Pain in rheumatoid arthritis: Emerging role of high mobility group box 1 protein-HMGB145
Editorial Board45
Editorial Board45
Comprehensive insights into the multifaceted roles of the transient receptor potential vanilloid 1 channel in the digestive system44
Oral fluoxetine treatment changes serotonergic sympatho-regulation in experimental type 1 diabetes44
Advances in siRNA delivery strategies for the treatment of MDR cancer43
Probenecid induces the recovery of renal ischemia/reperfusion injury via the blockade of Pannexin 1/P2X7 receptor axis43
Nerolidol attenuates dehydroepiandrosterone-induced polycystic ovary syndrome in rats by regulating oxidative stress and decreasing apoptosis43
The role of STIM1/ORAI1 channel in the analgesic effect of grain-sized moxibustion on inflammatory pain mice model42
17β-Estradiol alleviates intervertebral disc degeneration by inhibiting NF-κB signal pathway42
The potential protective effects of estradiol and 2-methoxyestradiol in ischemia reperfusion-induced kidney injury in ovariectomized female rats42
Anti-apoptotic and neurogenic properties in the hippocampus as possible mechanisms for learning and memory improving impacts of vitamin D in hypothyroid rats during the growth period42
Emerging role of glutamate in the pathophysiology and therapeutics of Gulf War illness42
In Vivo protection from SARS-CoV-2 infection by ATN-161 in k18-hACE2 transgenic mice41
Oxidative stress in animal models of obesity caused by hypercaloric diets: A systematic review41
Role of sulforaphane in endoplasmic reticulum homeostasis through regulation of the antioxidant response41
RETRACTED: Hepatocellular carcinoma cells-derived exosomal microRNA-378b enhances hepatocellular carcinoma angiogenesis41
Selective APC-targeting of a novel Fc-fusion multi-immunodominant recombinant protein (tTax-tEnv:mFcγ2a) for HTLV-1 vaccine development41
Phloretin as an add-on therapy to losartan attenuates diabetes-induced AKI in rats: A potential therapeutic approach targeting TLR4-induced inflammation41
Noxious ramifications of cosmetic pollutants on gastrointestinal microbiome: A pathway to neurological disorders41
A novel rat model of temporomandibular disorder with improved face and construct validities41
Renal cell carcinoma management: A step to nano-chemoprevention41
Pathophysiologic effects of waterpipe (shisha) smoke inhalation on liver morphology and function in mice41
Moderate intestinal immunopathology after acute oral infection with Toxoplasma gondii oocysts is associated with expressive levels of serotonin41
Important roles of linoleic acid and α-linolenic acid in regulating cognitive impairment and neuropsychiatric issues in metabolic-related dementia40
Understanding the physiological mechanisms and therapeutic targets of diseases: Lipidomics strategies40
Heparin prevents in vitro glycocalyx shedding induced by plasma from COVID-19 patients40
Oxidative and endoplasmic reticulum stress develop adverse metabolic effects due to the high-fat high-fructose diet consumption from birth to young adulthood40
8-Geranyloxycarbostyril as a potent 15-LOX-1 inhibitor showed great anti-tumor effects against prostate cancer40
Comprehensive review on mechanism of action, resistance and evolution of antimycobacterial drugs40
Mesenchymal stem cell-derived exosomes: Characteristics and applications in disease pathology and management40
Comparative transcriptome and Lipidome analyses suggest a lipid droplet-specific response to heat exposure of brown adipose tissue in normal and obese mice40
Interrogating Salmonella Typhi biofilm formation and dynamics to understand antimicrobial resistance39
Gigantol inhibits proliferation and enhances DDP-induced apoptosis in breast-cancer cells by downregulating the PI3K/Akt/mTOR signaling pathway39
The role of sleep disorders in cardiovascular diseases: Culprit or accomplice?39
Ursodeoxycholic acid alleviates atopic dermatitis-associated inflammatory responses in HaCaT and RBL-2H3 cells and DNCB/DFE-treated mice39
Exploring the therapeutic potential of tetrahydrobiopterin for heart failure with preserved ejection fraction: A path forward38
Low dose Taxol ameliorated renal fibrosis in mice with diabetic kidney disease by downregulation of HIPK238
Geniposide improves depression-like behavior in prenatal stress male offspring through restoring HPA axis- and glucocorticoid receptor-associated dysfunction38
LncRNA BACE1-AS enhances the invasive and metastatic capacity of hepatocellular carcinoma cells through mediating miR-377-3p/CELF1 axis38
Tauroursodeoxycholate prevents estradiol 17β-d-glucuronide-induced cholestasis and endocytosis of canalicular transporters by switching off pro-cholestatic signaling pathways38
Shining light on cardiac electrophysiology: From detection to intervention, from basic research to translational applications38
Altered GnRH neuron-glia networks close to interface of polycystic ovary syndrome: Molecular mechanism and clinical perspectives37
Unveiling OSCP as the potential therapeutic target for mitochondrial dysfunction-related diseases37
Aerobic exercise training attenuates ischemia-reperfusion injury in mice by decreasing the methylation level of METTL3-associated m6A RNA in cardiomyocytes37
Corrigendum to “Deferiprone and efonidipine mitigated iron-overload induced neurotoxicity in wild-type and thalassemic mice” [Life Sci. 239 (2019) 116878]37
Retraction notice to “Sevoflurane improves nerve regeneration and repair of neurological deficit in brain damage rats via microRNA-490-5p/CDK1 axis” [Life Sci. 271 (2021) 119111]37
CAMSAP2 enhances lung cancer cell metastasis by mediating RASAL2 degradation37
Retraction notice to “miR-98-5p inhibits gastric cancer cell stemness and chemoresistance by targeting branched-chain aminotransferases 1” [Life Sci. 276 (2021) 119405]37
Corrigendum to “Hydroxyl containing benzo[b]thiophene analogs mitigates the acrylamide induced oxidative stress in the zebrafish larvae by stabilizing the glutathione redox cycle” [Life Sci. 298 (202237
Imatinib mitigates experimentally-induced ulcerative colitis: Possible contribution of NF-kB/JAK2/STAT3/COX2 signaling pathway37
Tumor-associated macrophages: Potential target of natural compounds for management of breast cancer36
Study of immunomodulatory effects of mesenchymal stem cell-derived exosomes in a mouse model of LPS induced systemic inflammation36
The role of regulatory T cells in the pathogenesis and treatment of prostate cancer36
IKKβ inhibits cognitive memory and adult hippocampal neurogenesis by modulating the β-catenin pathway36
Cancer cell's internal and external warriors: Autophagosomes and exosomes36
5/6 nephrectomy affects enteric glial cells and promotes impaired antioxidant defense in the colonic neuromuscular layer36
Efficacy of lipid nanoparticles-based vaccine to protect against vulvovaginal candidiasis (VVC): Implications for women's reproductive health36
Quercetin mitigates memory deficits in scopolamine mice model via protection against neuroinflammation and neurodegeneration36
The hepatoprotective effects of n3-polyunsaturated fatty acids against non-alcoholic fatty liver disease in diabetic rats through the FOXO1/PPARα/GABARAPL1 signalling pathway36
Targeting calcium homeostasis and impaired inter-organelle crosstalk as a potential therapeutic approach in Parkinson's disease35
Modulating intestinal viruses: A potential avenue for improving metabolic diseases with unresolved challenges35
Contributions of the gut microbiota to Gulf War Illness susceptibility: Findings from a mouse model35
Supression Thioredoxin reductase 3 exacerbates the progression of liver cirrhosis via activation of ferroptosis pathway35
Nr2e1 deficiency aggravates insulin resistance and chronic inflammation of visceral adipose tissues in a diet-induced obese mice model35
Mollugin activates GLP-1R to improve cognitive dysfunction in type 2 diabetic mice35
An improved mouse model of sepsis based on intraperitoneal injections of the enriched culture of cecum slurry35
AP-2α decreases TMZ resistance of recurrent GBM by downregulating MGMT expression and improving DNA damage35
Modulation of cardiac voltage-activated K+ currents by glypican 1 heparan sulfate proteoglycan35
Altered sperm fate in the reproductive tract milieu due to oxidative stress leads to sub-fertility in type 1 diabetes females: A Drosophila-based study35
Ser235 phosphorylation of hepatitis C virus NS5A is required for NS5A dimerization and drug resistance35
Cyanocobalamin and/or calcitriol mitigate renal damage-mediated by tamoxifen in rats: Implication of caspase-3/NF-κB signaling pathways35
An analysis of the biopharmaceutical behaviour of proton pump inhibitors with different physicochemical properties34
Effect of Baricitinib on TPA-induced psoriasis like skin inflammation34
Therapeutic applications of mesenchymal/medicinal stem/signaling cells preconditioned with external factors: Are there more efficient approaches to utilize their regenerative potential?34
Fecal microbiota transplantation for diseases: Therapeutic potential, methodology, risk management in clinical practice34
Simvastatin reduces plasma membrane caveolae and caveolin-1 in uterine leiomyomas34
Update on the transdifferentiation of pancreatic cells into functional beta cells for treating diabetes34
Hypoxia activates SUMO-1-HIF-1α signaling pathway to upregulate pro-inflammatory cytokines and permeability in human tonsil epithelial cells34
TAD1822-7 induces ROS-mediated apoptosis of HER2 positive breast cancer by decreasing E-cadherin in an EphB4 dependent manner34
The Rab GTPase in the heart: Pivotal roles in development and disease34
The role of viruses in cancer progression versus cancer treatment: A dual paradigm34
Oxidative stress imposed in vivo anticancer therapeutic efficacy of novel imidazole-based oxidovanadium (IV) complex in solid tumor34
Pentadecapeptide BPC 157 efficiently reduces radiation-induced liver injury and lipid accumulation through Kruppel-like factor 4 upregulation both in vivo and in vitro34
Nesfatin-1 ameliorates oxidative brain damage and memory impairment in rats induced with a single acute epileptic seizure34
CD44s and CD44v8-10 isoforms confer acquired resistance to osimertinib by activating the ErbB3/STAT3 signaling pathway33
The influence of microenvironment stiffness on endothelial cell fate: Implication for occurrence and progression of atherosclerosis33
Maladaptive plasticity induced by morphine is mediated by hippocampal astrocytic Connexin-4333
Catechins prevent obesity-induced kidney damage by modulating PPARγ/CD36 pathway and gut-kidney axis in rats33
A new view on functions of the lysine demalonylase activity of SIRT533
N-acetylcysteine alleviates oxidative stress and apoptosis and prevents skeletal muscle atrophy in type 1 diabetes mellitus through the NRF2/HO-1 pathway32
The potential of sertoli cells (SCs) derived exosomes and its therapeutic efficacy in male reproductive disorders32
Hyperhomocysteinemia alters cytokine gene expression, cytochrome c oxidase activity and oxidative stress in striatum and cerebellum of rodents32
Exosomal-long non-coding RNAs journey in colorectal cancer: Evil and goodness faces of key players32
XQ-1H promotes cerebral angiogenesis via activating PI3K/Akt/GSK3β/β-catenin/VEGF signal in mice exposed to cerebral ischemic injury32
PXDNL activates the motility of urothelial bladder carcinoma cells through the Wnt/β-catenin pathway and has a prognostic value32
Evaluating the influence of Human Umbilical Cord Mesenchymal Stem Cells-derived exosomes loaded with miR-3182 on metastatic performance of Triple Negative Breast Cancer cells32
Restoration of dysbiotic human gut microbiome for homeostasis32
The physical exercise-induced oxidative/inflammatory response in peripheral blood mononuclear cells: Signaling cellular energetic stress situations32
MicroRNA-150 inhibits myeloid-derived suppressor cells proliferation and function through negative regulation of ARG-1 in sepsis32
Covid-19 a triggering factor of autoimmune and multi-inflammatory diseases32
ZD-2, a novel DPP4 inhibitor, protects islet β-cell and improves glycemic control in high-fat-diet-induced obese mice31
Novel GLP-1/anti-apolipoprotein B bifunctional fusion protein alleviates diabetes and diabetic complications in combination with low-intensity ultrasound31
Semaglutide alleviates the pancreatic β cell function via the METTL14 signaling and modulating gut microbiota in type 2 diabetes mellitus mice31
Editorial Board31
Survivin expression is essential for early activation of hepatic stellate cells and fibrosis progression in chronic liver injury31
Part-time cancers and role of melatonin in determining their metabolic phenotype31
5-((7-Chloro-6-fluoro-1h-indol-3-yl) methyl)-3-methylimidazolidine-2,4-dione as a RIP1 inhibitor protects LPS/D-galactosamine-induced liver failure31
Editorial Board31
Genetics, epigenetics and autoimmunity constitute a Bermuda triangle for the pathogenesis of rheumatoid arthritis31
Uterine anomalies in cell proliferation, energy homeostasis and oxidative stress in PCOS hamsters, M. auratus: Therapeutic potentials of melatonin31
Refined immunoRNases for the efficient targeting and selective killing of tumour cells: A novel strategy31
High-fat diet-induced obesity amplifies HSP70-2a and HSP90 expression in testicular tissue; correlation with proliferating cell nuclear antigen (PCNA)30
Heterodimerization of apelin and opioid receptor-like 1 receptors mediates apelin-13-induced G protein biased signaling30
Editorial Board30
MicroRNA-217 modulates pancreatic cancer progression via targeting ATAD230
Inhibition of the FOXO1–ROCK1 axis mitigates cardiomyocyte injury under chronic hypoxia in Tetralogy of Fallot by maintaining mitochondrial quality control30
SIRT6 inhibits hypoxia-induced pulmonary arterial smooth muscle cells proliferation via HIF-1α/PDK4 signaling30
Quercetin stimulates the non-amyloidogenic pathway via activation of ADAM10 and ADAM17 gene expression in aluminum chloride-induced Alzheimer's disease rat model30
Protective effects of low-temperature plasma on cisplatin-induced nephrotoxicity30
Gut microbiota in obesity and related complications: Unveiling the complex interplay30
Cryopreserved clinical-grade human embryonic stem cell-derived dopaminergic progenitors function in Parkinson's disease models30
Hyperoxic exposure alters intracellular bioenergetics distribution in human pulmonary cells30
Mesenchymal stem cell-based therapy as a new therapeutic approach for acute inflammation30
Challenges in clinical practice, biological mechanism and prospects of physical ablation therapy for COPD30
Anti-inflammatory activity of carvacrol protects the heart from lipopolysaccharide-induced cardiac dysfunction by inhibiting pyroptosis via NLRP3/Caspase1/Gasdermin D signaling axis30
N-phenethyl-5-phenylpicolinamide alleviates inflammation in acute lung injury by inhibiting HIF-1α/glycolysis/ASIC1a pathway29
Nickel chloride promotes lung cancer invasion and metastasis by up-regulating the expression of E3 ubiquitin ligase TRIM31 through the IL-6/STAT3 signaling axis29
Emerging role of mitochondrial DAMPs, aberrant mitochondrial dynamics and anomalous mitophagy in gut mucosal pathogenesis29
Auto- and paracrine rewiring of NIX-mediated mitophagy by insulin-like growth factor-binding protein 7 in septic AKI escalates inflammation-coupling tubular damage29
Fgf21-Dubosiella axis mediates the protective effects of exercise against NAFLD development29
Identification of distinct immune infiltration and potential biomarkers in patients with liver ischemia-reperfusion injury29
Organ-restricted delivery through stimuli-responsive nanocarriers for lung cancer therapy29
S1PR2/Wnt3a/RhoA/ROCK1/β-catenin signaling pathway promotes diabetic nephropathy by inducting endothelial mesenchymal transition and impairing endothelial barrier function29
Mechanism and regulation of mitophagy in nonalcoholic fatty liver disease (NAFLD): A mini-review29
Electroacupuncture for weight loss by regulating microglial polarization in the arcuate nucleus of the hypothalamus29
Distinct roles for orexin-1 and orexin-2 receptors in the dentate gyrus of the hippocampus in the methamphetamine-seeking behavior in the rats29
Gastrointestinal manifestations of long COVID29
LncRNA DLEU2 is activated by STAT1 and induces gastric cancer development via targeting miR-23b-3p/NOTCH2 axis and Notch signaling pathway29
Rodent models for dry eye syndrome: Standardization using benzalkonium chloride and scopolamine hydrobromide29
Therapeutic role of extracellular vesicles derived from stem cells in cutaneous wound models: A systematic review29
Astragaloside IV-targeting miRNA-1 attenuates lipopolysaccharide-induced cardiac dysfunction in rats through inhibition of apoptosis and autophagy29
Synovial microenvironment in temporomandibular joint osteoarthritis: crosstalk with chondrocytes and potential therapeutic targets29
Antibacterial activity and metabolomic analysis of linalool against bovine mastitis pathogen Streptococcus agalactiae29
Omega-3 fatty acids prevent nicotine withdrawal-induced impairment of learning and memory via affecting oxidative status, inflammatory response, cholinergic activity, BDNF and amyloid-B in rat hippoca28
Antineoplastic agents in chemotherapy facilitating tumor growth and angiogenesis in the interval administrations28
Potential therapeutic and diagnostic approaches of exosomes in multiple sclerosis pathophysiology28
Dysregulation of immune and metabolism pathways in maternal immune activation induces an increased risk of autism spectrum disorders28
WITHDRAWN: Smooth muscle cell-specific knockout of interferon gamma (IFN-γ) receptor attenuates intimal hyperplasia via STAT1-KLF4 activation28
MicroRNA-23b prevents aortic aneurysm formation by inhibiting smooth muscle cell phenotypic switching via FoxO4 suppression28
Cancer immunotherapy resistance: The impact of microbiome-derived short-chain fatty acids and other emerging metabolites28
Identification of inflammation related lncRNAs and Gm33647 as a potential regulator in septic acute lung injury28
Exosomal miR-1228-5p down-regulates DUSP22 to promotes cell proliferation and migration in small cell lung cancer28
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