OOIR: Observatory of International Research

Papers

(The H4-Index of Life Sciences is 56. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
Insights into the development of insulin-producing cells: Precursors correlated involvement of microRNA panels	378
Cross-species gene expression patterns of purinergic signaling in the human and mouse trigeminal ganglion	361
Cigarette smoking-related OLC1 overexpression associated with poor prognosis in bladder urothelial carcinoma	236
Coadministration of olanzapine causes minor impacts on the diabetogenic outcomes induced by dexamethasone treatment in rats	217
Regulation of metabolism by circadian rhythms: Support from time-restricted eating, intestinal microbiota & omics analysis	172
Altering phosphorylation of dystrophin S3059 to attenuate cancer cachexia	156
6-NitroDopamine is an endogenous modulator of rat heart chronotropism	155
Mitochondrial transfer in the progression and treatment of cardiac disease	154
Ergosterol promotes neurite outgrowth, inhibits amyloid-beta synthesis, and extends longevity: In vitro neuroblastoma and in vivo Caenorhabditis elegans evidence	153
Carboxyaminotriazole: A bone savior in collagen-induced arthritis—Halting osteoclastogenesis via interleukin-1β downregulation	148
Characterizing COPD phenotypes with a targeted signaling lipids metabolomics approach	131
Hyperglycemia influences the cell proliferation and death of the rat endocrine pancreas in the neonatal period	121
Editorial Board	113
The chromatin remodeling protein BRG1 mediates Ang II induced pro-fibrogenic response in renal fibroblasts	105
Retraction notice to “Inhibition of CD73 using folate targeted nanoparticles carrying anti-CD73 siRNA potentiates anticancer efficacy of Dinaciclib” [Life Sci. 259 (2020) 118150]	98
TRIM21 ubiquitylates GPX4 and promotes ferroptosis to aggravate ischemia/reperfusion-induced acute kidney injury	94
Myeloid derived suppressor cells and innate immune system interaction in tumor microenvironment	86
A detailed insight into macrophages' role in shaping lung carcinogenesis	85
The role of exosomes in the molecular mechanisms of metastasis: Focusing on EMT and cancer stem cells	85
Copper homeostasis and cuproptosis in mitochondria	81
High fat diet exacerbates long-term metabolic, neuropathological, and behavioral derangements in an experimental mouse model of traumatic brain injury	77
Metabolomics profiling and chemoresistance mechanisms in ovarian cancer cell lines: Implications for targeting glutathione pathway	75
Ablation of Brg1 in fibroblast/myofibroblast lineages attenuates renal fibrosis in mice with diabetic nephropathy	73
Gold nanoparticles show potential in vitro antiviral and anticancer activity	72
Ivabradine restores tonic cardiovascular autonomic control and reduces tachycardia, hypertension and left ventricular inflammation in post-weaning protein malnourished rats	72

Autophagy deficiency exacerbated hypoxia-reoxygenation induced inflammation and cell death via a mitochondrial DNA/STING/IRF3 pathway	72
CKN reduces TLR4-mediated inflammation and cerebral I/R injury by activating the LXRα/ABCA1 pathway in microglia	72
Emerging therapeutic landscape: Incretin agonists in chronic kidney disease management	71
Protective role of ellagic acid and taurine against fluoxetine induced hepatotoxic effects on biochemical and oxidative stress parameters, histopathological changes, and gene expressions of IL-1β, NF-	70
Pancreastatin inhibitor PSTi8 prevents free fatty acid-induced oxidative stress and insulin resistance by modulating JNK pathway: In vitro and in vivo findings	70
Mebendazole; from an anti-parasitic drug to a promising candidate for drug repurposing in colorectal cancer	70
Rhein ameliorates septic lung injury and intervenes in macrophage metabolic reprogramming in the inflammatory state by Sirtuin 1	67
Physical health, behavioral and emotional functioning in children of gulf war veterans	67
Dysregulated pancreatic lipid phenotype, inflammation and cellular injury in a chronic ethanol feeding model of hepatic alcohol dehydrogenase-deficient deer mice	67
Lung cancer vaccination from concept to reality: A critical review of clinical trials and latest advances	66
Unleashing the pathological imprinting of cancer in autoimmunity: Is ZEB1 the answer?	66
Application of f-FeNC@GOx cascade enzyme nanomaterials in the healing of infected wounds	66
Spontaneous and familial models of Alzheimer's disease: Challenges and advances in preclinical research	65
The C C motif chemokine ligand 11 contributes to alcoholic liver disease	65
Targeting HMG-CoA synthase 2 suppresses tamoxifen-resistant breast cancer growth by augmenting mitochondrial oxidative stress-mediated cell death	64
The combination of mesenchymal stem cell- and hepatocyte-derived exosomes, along with imipenem, ameliorates inflammatory responses and liver damage in a sepsis mouse model	63
Transcranial alternating current stimulation inhibits ferroptosis and promotes functional recovery in spinal cord injury via the cGMP-PKG signalling pathway	63
Liraglutide attenuates intestinal ischemia/reperfusion injury via NF-κB and PI3K/Akt pathways in mice	62
Melatonin: A potential protective multifaceted force for sepsis-induced cardiomyopathy	61
Progesterone signaling in uterine fibroids: Molecular mechanisms and therapeutic opportunities	60
Targeting GAS6/AXL signaling improves the response to immunotherapy by restoring the anti-immunogenic tumor microenvironment in gastric cancer	60
γ-Aminobutyric acid promotes the inhibition of hair growth induced by chronic restraint stress	59
Hesperidin attenuates hepatic lipid accumulation in mice fed high-fat diet and oleic acid induced HepG2 via AMPK activation	58
Effect of folate-targeted Erlotinib loaded human serum albumin nanoparticles on tumor size and survival rate in a rat model of glioblastoma	58
Exercise training and probiotic supplementation effects on skeletal muscle apoptosis prevention in type-Ι diabetic rats	57
The proteomic landscape of ovarian cancer cells in response to melatonin	57
The combined therapy of mesenchymal stem cell transplantation and resveratrol for diabetes: Future applications and challenges	56
Skp2-mediated Zeb1 expression facilitates cancer migration by a ubiquitination-independent pathway	56
Antioxidant therapy reverses sympathetic dysfunction, oxidative stress, and hypertension in male hyperadipose rats	56
4-Methylumbelliferone induces antitumor effects independently of hyaluronan synthesis inhibition in human acute leukemia cell lines	56
Optimal intervention time of ADSCs for hepatic ischemia-reperfusion combined with partial resection injury in rats	56