OOIR: Observatory of International Research

Papers

(The H4-Index of Life Sciences is 58. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Cigarette smoking-related OLC1 overexpression associated with poor prognosis in bladder urothelial carcinoma	308
Cross-species gene expression patterns of purinergic signaling in the human and mouse trigeminal ganglion	272
Skp2-mediated Zeb1 expression facilitates cancer migration by a ubiquitination-independent pathway	221
The inhibition of autophagy by spautin boosts the anticancer activity of fingolimod in multidrug-resistant hepatocellular carcinoma	204
A detailed insight into macrophages' role in shaping lung carcinogenesis	138
Editorial Board	137
Ablation of Brg1 in fibroblast/myofibroblast lineages attenuates renal fibrosis in mice with diabetic nephropathy	127
Ivabradine restores tonic cardiovascular autonomic control and reduces tachycardia, hypertension and left ventricular inflammation in post-weaning protein malnourished rats	123
The dynamicity of mutant KRAS β2 strand modulates its downstream activation and predicts anticancer KRAS inhibition	120
Insights into the development of insulin-producing cells: Precursors correlated involvement of microRNA panels	117
Effect of folate-targeted Erlotinib loaded human serum albumin nanoparticles on tumor size and survival rate in a rat model of glioblastoma	107
Melatonin: A potential protective multifaceted force for sepsis-induced cardiomyopathy	103
Retraction notice to “Inhibition of CD73 using folate targeted nanoparticles carrying anti-CD73 siRNA potentiates anticancer efficacy of Dinaciclib” [Life Sci. 259 (2020) 118150]	100
The N6-methyladenosine modification in pathologic angiogenesis	99
HDAC11 deficiency improves muscle phenotype in a Duchenne muscular dystrophy murine model by reducing inflammation and fibrosis	95
Lung cancer vaccination from concept to reality: A critical review of clinical trials and latest advances	93
Repurposing therapeutics for malignant pleural mesothelioma (MPM) – Updates on clinical translations and future outlook	92
Characterizing COPD phenotypes with a targeted signaling lipids metabolomics approach	91
Identification of specific gut microbes and their therapeutic potential in ameliorating systemic lupus erythematosus in a mouse model	89
Dysregulated pancreatic lipid phenotype, inflammation and cellular injury in a chronic ethanol feeding model of hepatic alcohol dehydrogenase-deficient deer mice	87
Behavioural disruption in diabetic mice: Neurobiological correlates and influences of dietary α-linolenic acid	86
Unleashing the pathological imprinting of cancer in autoimmunity: Is ZEB1 the answer?	86
The role of endoplasmic reticulum aminopeptidases in type 1 diabetes mellitus	85
Metacaspase (Pf MCA-1) as antimalarial drug target: An in silico approach and their biological validation	83
Altering phosphorylation of dystrophin S3059 to attenuate cancer cachexia	82

CKN reduces TLR4-mediated inflammation and cerebral I/R injury by activating the LXRα/ABCA1 pathway in microglia	82
Screening strategy using a filamentous fungus model to repurpose drugs for mitochondrial complex I deficiencies	82
The chromatin remodeling protein BRG1 mediates Ang II induced pro-fibrogenic response in renal fibroblasts	82
Tuberous sclerosis complex 2 deficiency in cardiomyocytes exacerbates cardiac remodeling in diabetic mice	81
Role of left and right vagus nerves in linking peripheral adrenergic signals to contextual fear memory	81
Environmental bacteria as triggers to brain disease: Possible mechanisms of toxicity and associated human risk	80
Myeloid derived suppressor cells and innate immune system interaction in tumor microenvironment	77
Targeting GAS6/AXL signaling improves the response to immunotherapy by restoring the anti-immunogenic tumor microenvironment in gastric cancer	76
Downregulation of CDC42 contributes to pulmonary vascular endothelial hyperpermeability and acute lung injury induced by seawater drowning	75
Carvacrol enhances anti-tumor activity and mitigates cardiotoxicity of sorafenib in thioacetamide-induced hepatocellular carcinoma model through inhibiting TRPM7	75
Dehydroepiandrosterone activates the GPER-mediated AMPK signaling pathway to alleviate the oxidative stress and inflammatory response in laying hens fed with high-energy and low-protein diets	73
Human gestational diabetes mellitus–derived exosomes impair glucose homeostasis in pregnant mice and stimulate functional maturation of offspring-islets	72
Upregulation of miR-222-3p alleviates the symptom of aortic dissection through targeting STAT3	71
Metabolomics profiling and chemoresistance mechanisms in ovarian cancer cell lines: Implications for targeting glutathione pathway	71
Augmented nephroprotective effect of liraglutide and rabeprazole via inhibition of OCT2 transporter in cisplatin-induced nephrotoxicity in rats	70
Emerging therapeutic landscape: Incretin agonists in chronic kidney disease management	69
Exploring Lin28 proteins: Unravelling structure and functions with emphasis on nervous system malignancies	68
6-NitroDopamine is an endogenous modulator of rat heart chronotropism	67
Combined effects of high fat diet and exercise on autophagy in white adipose tissue of mice	67
γ-Aminobutyric acid promotes the inhibition of hair growth induced by chronic restraint stress	67
Spontaneous and familial models of Alzheimer's disease: Challenges and advances in preclinical research	66
Application of f-FeNC@GOx cascade enzyme nanomaterials in the healing of infected wounds	66
Hyperglycemia influences the cell proliferation and death of the rat endocrine pancreas in the neonatal period	64
The combination of mesenchymal stem cell- and hepatocyte-derived exosomes, along with imipenem, ameliorates inflammatory responses and liver damage in a sepsis mouse model	64
Liraglutide attenuates intestinal ischemia/reperfusion injury via NF-κB and PI3K/Akt pathways in mice	64
Sulforaphane regulates Nrf2-mediated antioxidant activity and downregulates TGF-β1/Smad pathways to prevent radiation-induced muscle fibrosis	64
Salvianolic acid A inhibits tumor cell proliferation and induces chromosomal abnormalities by blocking the citrullinating enzyme PADs	63
Progesterone signaling in uterine fibroids: Molecular mechanisms and therapeutic opportunities	63
Protective role of ellagic acid and taurine against fluoxetine induced hepatotoxic effects on biochemical and oxidative stress parameters, histopathological changes, and gene expressions of IL-1β, NF-	59
Transcranial alternating current stimulation inhibits ferroptosis and promotes functional recovery in spinal cord injury via the cGMP-PKG signalling pathway	59
Coadministration of olanzapine causes minor impacts on the diabetogenic outcomes induced by dexamethasone treatment in rats	59
Ergosterol promotes neurite outgrowth, inhibits amyloid-beta synthesis, and extends longevity: In vitro neuroblastoma and in vivo Caenorhabditis elegans evidence	59
The role of exosomes in the molecular mechanisms of metastasis: Focusing on EMT and cancer stem cells	58
High fat diet exacerbates long-term metabolic, neuropathological, and behavioral derangements in an experimental mouse model of traumatic brain injury	58