OOIR: Observatory of International Research

Papers

(The H4-Index of Life Sciences is 55. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Metacaspase (Pf MCA-1) as antimalarial drug target: An in silico approach and their biological validation	307
4-Methylumbelliferone induces antitumor effects independently of hyaluronan synthesis inhibition in human acute leukemia cell lines	302
Insights into the development of insulin-producing cells: Precursors correlated involvement of microRNA panels	277
Ergosterol promotes neurite outgrowth, inhibits amyloid-beta synthesis, and extends longevity: In vitro neuroblastoma and in vivo Caenorhabditis elegans evidence	197
Behavioural disruption in diabetic mice: Neurobiological correlates and influences of dietary α-linolenic acid	186
The role of endoplasmic reticulum aminopeptidases in type 1 diabetes mellitus	179
Skp2-mediated Zeb1 expression facilitates cancer migration by a ubiquitination-independent pathway	161
Rhein ameliorates septic lung injury and intervenes in macrophage metabolic reprogramming in the inflammatory state by Sirtuin 1	150
Targeting GAS6/AXL signaling improves the response to immunotherapy by restoring the anti-immunogenic tumor microenvironment in gastric cancer	142
Indole-3-carbinol induces apoptosis-like death in Escherichia coli on different contribution of respective reactive oxygen species	133
Augmented nephroprotective effect of liraglutide and rabeprazole via inhibition of OCT2 transporter in cisplatin-induced nephrotoxicity in rats	132
Ablation of Brg1 in fibroblast/myofibroblast lineages attenuates renal fibrosis in mice with diabetic nephropathy	127
The combination of mesenchymal stem cell- and hepatocyte-derived exosomes, along with imipenem, ameliorates inflammatory responses and liver damage in a sepsis mouse model	126
Cross-species gene expression patterns of purinergic signaling in the human and mouse trigeminal ganglion	124
Exploring Lin28 proteins: Unravelling structure and functions with emphasis on nervous system malignancies	121
The N6-methyladenosine modification in pathologic angiogenesis	119
Coadministration of olanzapine causes minor impacts on the diabetogenic outcomes induced by dexamethasone treatment in rats	119
Ivabradine restores tonic cardiovascular autonomic control and reduces tachycardia, hypertension and left ventricular inflammation in post-weaning protein malnourished rats	118
Regulation of metabolism by circadian rhythms: Support from time-restricted eating, intestinal microbiota & omics analysis	105
Cigarette smoking-related OLC1 overexpression associated with poor prognosis in bladder urothelial carcinoma	87
Exercise training and probiotic supplementation effects on skeletal muscle apoptosis prevention in type-Ι diabetic rats	86
The proteomic landscape of ovarian cancer cells in response to melatonin	85
Pancreastatin inhibitor PSTi8 prevents free fatty acid-induced oxidative stress and insulin resistance by modulating JNK pathway: In vitro and in vivo findings	85
The inhibition of autophagy by spautin boosts the anticancer activity of fingolimod in multidrug-resistant hepatocellular carcinoma	84
Optimal intervention time of ADSCs for hepatic ischemia-reperfusion combined with partial resection injury in rats	84

Renal protective effects and mechanisms of the angiotensin receptor-neprilysin inhibitor LCZ696 in mice with cardiorenal syndrome	84
Physical health, behavioral and emotional functioning in children of gulf war veterans	84
Transcranial alternating current stimulation inhibits ferroptosis and promotes functional recovery in spinal cord injury via the cGMP-PKG signalling pathway	82
Mitochondrial transfer in the progression and treatment of cardiac disease	81
Emerging therapeutic landscape: Incretin agonists in chronic kidney disease management	81
The role of exosomes in the molecular mechanisms of metastasis: Focusing on EMT and cancer stem cells	80
Gulf War Illness Clinical Trials and Interventions Consortium (GWICTIC): A collaborative research infrastructure for intervention and implementation	80
Antioxidant therapy reverses sympathetic dysfunction, oxidative stress, and hypertension in male hyperadipose rats	79
The anxiolytic sertraline reduces the impact of psychological stress on bladder function in mice	78
The C C motif chemokine ligand 11 contributes to alcoholic liver disease	74
Carboxyaminotriazole: A bone savior in collagen-induced arthritis—Halting osteoclastogenesis via interleukin-1β downregulation	73
Characterizing COPD phenotypes with a targeted signaling lipids metabolomics approach	71
Altering phosphorylation of dystrophin S3059 to attenuate cancer cachexia	70
Editorial Board	68
Hyperglycemia influences the cell proliferation and death of the rat endocrine pancreas in the neonatal period	68
The dynamicity of mutant KRAS β2 strand modulates its downstream activation and predicts anticancer KRAS inhibition	67
The combined therapy of mesenchymal stem cell transplantation and resveratrol for diabetes: Future applications and challenges	67
Human gestational diabetes mellitus–derived exosomes impair glucose homeostasis in pregnant mice and stimulate functional maturation of offspring-islets	64
The chromatin remodeling protein BRG1 mediates Ang II induced pro-fibrogenic response in renal fibroblasts	64
Environmental bacteria as triggers to brain disease: Possible mechanisms of toxicity and associated human risk	61
Retraction notice to “Inhibition of CD73 using folate targeted nanoparticles carrying anti-CD73 siRNA potentiates anticancer efficacy of Dinaciclib” [Life Sci. 259 (2020) 118150]	61
Unleashing the pathological imprinting of cancer in autoimmunity: Is ZEB1 the answer?	60
Combined effects of high fat diet and exercise on autophagy in white adipose tissue of mice	60
Progesterone signaling in uterine fibroids: Molecular mechanisms and therapeutic opportunities	59
Sulforaphane regulates Nrf2-mediated antioxidant activity and downregulates TGF-β1/Smad pathways to prevent radiation-induced muscle fibrosis	58
Evidence-based hormonal, mutational, and endocrine-disrupting chemical-induced zebrafish as an alternative model to study PCOS condition similar to mammalian PCOS model	57
6-NitroDopamine is an endogenous modulator of rat heart chronotropism	57
Integrin αvβ3 and disulfide bonds play important roles in NGR-retargeted adenovirus transduction efficiency	57
Myeloid derived suppressor cells and innate immune system interaction in tumor microenvironment	56
Liraglutide attenuates intestinal ischemia/reperfusion injury via NF-κB and PI3K/Akt pathways in mice	56
γ-Aminobutyric acid promotes the inhibition of hair growth induced by chronic restraint stress	55
Targeting pyruvate kinase muscle isoform 2 (PKM2) in cancer: What do we know so far?	55
Mebendazole; from an anti-parasitic drug to a promising candidate for drug repurposing in colorectal cancer	55