Life Sciences

Papers
(The H4-Index of Life Sciences is 71. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)
ArticleCitations
Ribavirin, Remdesivir, Sofosbuvir, Galidesivir, and Tenofovir against SARS-CoV-2 RNA dependent RNA polymerase (RdRp): A molecular docking study648
Anti-HCV, nucleotide inhibitors, repurposing against COVID-19476
The role of biomarkers in diagnosis of COVID-19 – A systematic review452
COVID-19: Melatonin as a potential adjuvant treatment438
Myocardial injury and COVID-19: Possible mechanisms306
Virtual screening and repurposing of FDA approved drugs against COVID-19 main protease271
In silico studies on therapeutic agents for COVID-19: Drug repurposing approach270
Contribution of monocytes and macrophages to the local tissue inflammation and cytokine storm in COVID-19: Lessons from SARS and MERS, and potential therapeutic interventions230
Role of gut-brain axis, gut microbial composition, and probiotic intervention in Alzheimer's disease215
The mechanisms of lysophosphatidylcholine in the development of diseases208
The role of CREB and BDNF in neurobiology and treatment of Alzheimer's disease197
The immune system and COVID-19: Friend or foe?193
PI3K/AKT/mTOR signaling in gastric cancer: Epigenetics and beyond185
A review on anti-cancer properties of Quercetin in breast cancer183
Ferulic acid: A review of its pharmacology, pharmacokinetics and derivatives174
Mechanisms of lncRNA/microRNA interactions in angiogenesis169
Structural features of coronavirus SARS-CoV-2 spike protein: Targets for vaccination165
DNA vaccines against COVID-19: Perspectives and challenges163
A comprehensive review on time-tested anticancer drug doxorubicin162
LncRNA PVT1 regulates ferroptosis through miR-214-mediated TFR1 and p53152
Coronaviruses pathogenesis, comorbidities and multi-organ damage – A review151
Nrf2/Keap1/ARE signaling: Towards specific regulation148
The role of cytokine profile and lymphocyte subsets in the severity of coronavirus disease 2019 (COVID-19): A systematic review and meta-analysis140
New molecular and biochemical insights of doxorubicin-induced hepatotoxicity133
Protective role of ACE2 and its downregulation in SARS-CoV-2 infection leading to Macrophage Activation Syndrome: Therapeutic implications131
Alzheimer's disease; a review of the pathophysiological basis and therapeutic interventions127
Targeted doxorubicin-loaded mesenchymal stem cells-derived exosomes as a versatile platform for fighting against colorectal cancer126
Exosomal miR-4443 promotes cisplatin resistance in non-small cell lung carcinoma by regulating FSP1 m6A modification-mediated ferroptosis119
Antimicrobial peptides – Advances in development of therapeutic applications111
Epigenetic modulation and understanding of HDAC inhibitors in cancer therapy108
Circulating microRNAs as biomarkers in cancer diagnosis107
Recent trends in cancer therapy: A review on the current state of gene delivery106
Revisiting the role of neurotransmitters in epilepsy: An updated review106
Free and hydrogel encapsulated exosome-based therapies in regenerative medicine104
Nanotechnology in ovarian cancer: Diagnosis and treatment103
Unravelling lead antiviral phytochemicals for the inhibition of SARS-CoV-2 Mpro enzyme through in silico approach103
Biosensors as a future diagnostic approach for COVID-19100
Galangin attenuated cerebral ischemia-reperfusion injury by inhibition of ferroptosis through activating the SLC7A11/GPX4 axis in gerbils99
Adult mesenchymal stem cells and their exosomes: Sources, characteristics, and application in regenerative medicine99
Potential therapeutic targets for combating SARS-CoV-2: Drug repurposing, clinical trials and recent advancements94
Lungs as target of COVID-19 infection: Protective common molecular mechanisms of vitamin D and melatonin as a new potential synergistic treatment94
Monocytes and macrophages in COVID-19: Friends and foes94
CXCL12/CXCR4 axis in the microenvironment of solid tumors: A critical mediator of metastasis93
Implicating the effect of ketogenic diet as a preventive measure to obesity and diabetes mellitus93
SARS-CoV-2 and coagulation disorders in different organs92
Curcumin in cancer therapy: A novel adjunct for combination chemotherapy with paclitaxel and alleviation of its adverse effects92
Immune escape: A critical hallmark in solid tumors92
Luteolin alleviates inflammation and modulates gut microbiota in ulcerative colitis rats90
Dendritic cell therapy in cancer treatment; the state-of-the-art90
Gene therapy: Comprehensive overview and therapeutic applications89
High GRP78 levels in Covid-19 infection: A case-control study88
Crosstalk between endoplasmic reticulum stress and anti-viral activities: A novel therapeutic target for COVID-1986
Synergic effects of nanoparticles-mediated hyperthermia in radiotherapy/chemotherapy of cancer86
Diosgenin, a steroidal saponin, and its analogs: Effective therapies against different chronic diseases84
Interplay between MAPK/ERK signaling pathway and MicroRNAs: A crucial mechanism regulating cancer cell metabolism and tumor progression84
A review on advances of treatment modalities for Alzheimer's disease84
Exosomal miR-21 secreted by IL-1β-primed-mesenchymal stem cells induces macrophage M2 polarization and ameliorates sepsis83
Utilizing drug repurposing against COVID-19 – Efficacy, limitations, and challenges83
The dual impact of ACE2 in COVID-19 and ironical actions in geriatrics and pediatrics with possible therapeutic solutions81
HMOX1 upregulation promotes ferroptosis in diabetic atherosclerosis80
Network pharmacology and molecular docking reveal the mechanism of Scopoletin against non-small cell lung cancer78
Exosomes from MSCs overexpressing microRNA-223-3p attenuate cerebral ischemia through inhibiting microglial M1 polarization mediated inflammation78
Pancreatic lipase inhibitors: The road voyaged and successes77
Quercetin alleviates kidney fibrosis by reducing renal tubular epithelial cell senescence through the SIRT1/PINK1/mitophagy axis77
Sp1-mediated upregulation of Prdx6 expression prevents podocyte injury in diabetic nephropathy via mitigation of oxidative stress and ferroptosis76
Unravelling the involvement of gut microbiota in type 2 diabetes mellitus76
Hyperbaric oxygen potentiates diabetic wound healing by promoting fibroblast cell proliferation and endothelial cell angiogenesis76
Tuberculosis vaccine: A journey from BCG to present74
Pretreatment of exosomes derived from hUCMSCs with TNF-α ameliorates acute liver failure by inhibiting the activation of NLRP3 in macrophage74
The pathophysiology of SARS-CoV-2: A suggested model and therapeutic approach73
Naringenin: A potential flavonoid phytochemical for cancer therapy73
Cigarette smoke extract induces pyroptosis in human bronchial epithelial cells through the ROS/NLRP3/caspase-1 pathway71
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