Laboratory Investigation

(The H4-Index of Laboratory Investigation is 29. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 500 papers]. The publications cover those that have been published in the past four years, i.e., from 2019-11-01 to 2023-11-01.)
Artificial intelligence and computational pathology173
Bone marrow mesenchymal stem cell-derived exosomal miR-144-5p improves rat ovarian function after chemotherapy-induced ovarian failure by targeting PTEN97
PI3K-Akt-mTOR/PFKFB3 pathway mediated lung fibroblast aerobic glycolysis and collagen synthesis in lipopolysaccharide-induced pulmonary fibrosis79
CCL8 secreted by tumor-associated macrophages promotes invasion and stemness of glioblastoma cells via ERK1/2 signaling73
Detection of SARS-CoV-2 in formalin-fixed paraffin-embedded tissue sections using commercially available reagents70
Retrospective analysis of laboratory testing in 54 patients with severe- or critical-type 2019 novel coronavirus pneumonia64
PI3K/Akt pathway-mediated HO-1 induction regulates mitochondrial quality control and attenuates endotoxin-induced acute lung injury63
Deep learning assisted mitotic counting for breast cancer61
Machine-based detection and classification for bone marrow aspirate differential counts: initial development focusing on nonneoplastic cells60
Grading of adult diffuse gliomas according to the 2021 WHO Classification of Tumors of the Central Nervous System54
STING expression in monocyte-derived macrophages is associated with the progression of liver inflammation and fibrosis in patients with nonalcoholic fatty liver disease53
Adipose mesenchymal stem cell-derived exosomes accelerate skin wound healing via the lncRNA H19/miR-19b/SOX9 axis49
Quantitative assessment of PD-L1 as an analyte in immunohistochemistry diagnostic assays using a standardized cell line tissue microarray48
RIP1/RIP3/MLKL mediates dopaminergic neuron necroptosis in a mouse model of Parkinson disease46
Role of macrophage TRPV4 in inflammation46
Multiplexed ion beam imaging (MIBI) for characterization of the tumor microenvironment across tumor types41
Quantitative measurement of HER2 expression to subclassify ERBB2 unamplified breast cancer40
CCL3–CCR5 axis contributes to progression of esophageal squamous cell carcinoma by promoting cell migration and invasion via Akt and ERK pathways40
N-methyladenosine reader YTHDF2-mediated long noncoding RNA FENDRR degradation promotes cell proliferation in endometrioid endometrial carcinoma39
The TRPV4-AKT axis promotes oral squamous cell carcinoma cell proliferation via CaMKII activation34
High-throughput proteomics: a methodological mini-review32
Vascular remodeling by placenta-derived mesenchymal stem cells restores ovarian function in ovariectomized rat model via the VEGF pathway32
Deep-learning-based accurate hepatic steatosis quantification for histological assessment of liver biopsies32
Automated computerized image analysis for the user-independent evaluation of disease severity in preclinical models of NAFLD/NASH31
The Shh/Gli signaling cascade regulates myofibroblastic activation of lung-resident mesenchymal stem cells via the modulation of Wnt10a expression during pulmonary fibrogenesis31
Cas9-based enrichment and single-molecule sequencing for precise characterization of genomic duplications31
miR-27a ameliorates chemoresistance of breast cancer cells by disruption of reactive oxygen species homeostasis and impairment of autophagy30
A new role for host annexin A2 in establishing bacterial adhesion to vascular endothelial cells: lines of evidence from atomic force microscopy and an in vivo study29
Advancements in detection of SARS-CoV-2 infection for confronting COVID-19 pandemics29