Laboratory Investigation

Papers
(The H4-Index of Laboratory Investigation is 28. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)
ArticleCitations
Artificial intelligence and computational pathology223
PI3K-Akt-mTOR/PFKFB3 pathway mediated lung fibroblast aerobic glycolysis and collagen synthesis in lipopolysaccharide-induced pulmonary fibrosis102
CCL8 secreted by tumor-associated macrophages promotes invasion and stemness of glioblastoma cells via ERK1/2 signaling86
Detection of SARS-CoV-2 in formalin-fixed paraffin-embedded tissue sections using commercially available reagents73
Grading of adult diffuse gliomas according to the 2021 WHO Classification of Tumors of the Central Nervous System71
High-throughput proteomics: a methodological mini-review68
Retrospective analysis of laboratory testing in 54 patients with severe- or critical-type 2019 novel coronavirus pneumonia67
STING expression in monocyte-derived macrophages is associated with the progression of liver inflammation and fibrosis in patients with nonalcoholic fatty liver disease61
Adipose mesenchymal stem cell-derived exosomes accelerate skin wound healing via the lncRNA H19/miR-19b/SOX9 axis55
Quantitative measurement of HER2 expression to subclassify ERBB2 unamplified breast cancer53
Multiplexed ion beam imaging (MIBI) for characterization of the tumor microenvironment across tumor types49
N-methyladenosine reader YTHDF2-mediated long noncoding RNA FENDRR degradation promotes cell proliferation in endometrioid endometrial carcinoma43
CCL3–CCR5 axis contributes to progression of esophageal squamous cell carcinoma by promoting cell migration and invasion via Akt and ERK pathways42
Vascular remodeling by placenta-derived mesenchymal stem cells restores ovarian function in ovariectomized rat model via the VEGF pathway38
Deep-learning-based accurate hepatic steatosis quantification for histological assessment of liver biopsies37
Deep learning shows the capability of high-level computer-aided diagnosis in malignant lymphoma36
Advancements in detection of SARS-CoV-2 infection for confronting COVID-19 pandemics34
PAI-1 derived from cancer-associated fibroblasts in esophageal squamous cell carcinoma promotes the invasion of cancer cells and the migration of macrophages32
Exosomal tau with seeding activity is released from Alzheimer's disease synapses, and seeding potential is associated with amyloid beta32
Wolfram syndrome 1 gene regulates pathways maintaining beta-cell health and survival32
Polydatin protects against lipopolysaccharide-induced endothelial barrier disruption via SIRT3 activation32
miR-27a ameliorates chemoresistance of breast cancer cells by disruption of reactive oxygen species homeostasis and impairment of autophagy31
The lncRNA XIST/miR-150-5p/c-Fos axis regulates sepsis-induced myocardial injury via TXNIP-modulated pyroptosis30
Fibronectin 1 activates WNT/β-catenin signaling to induce osteogenic differentiation via integrin β1 interaction30
Brightfield multiplex immunohistochemistry with multispectral imaging30
3′ MACE RNA-sequencing allows for transcriptome profiling in human tissue samples after long-term storage29
MicroRNA-182 improves spinal cord injury in mice by modulating apoptosis and the inflammatory response via IKKβ/NF-κB29
CircRNA-ST6GALNAC6 increases the sensitivity of bladder cancer cells to erastin-induced ferroptosis by regulating the HSPB1/P38 axis29
Predictive modeling of estrogen receptor agonism, antagonism, and binding activities using machine- and deep-learning approaches28
Th17/IL-17 induces endothelial cell senescence via activation of NF-κB/p53/Rb signaling pathway28
Nicotinamide riboside, an NAD+ precursor, attenuates inflammation and oxidative stress by activating sirtuin 1 in alcohol-stimulated macrophages28
Exosomes derived from hypoxic glioma deliver miR-1246 and miR-10b-5p to normoxic glioma cells to promote migration and invasion28
Hemoglobin oxidation generates globin-derived peptides in atherosclerotic lesions and intraventricular hemorrhage of the brain, provoking endothelial dysfunction28
Establishing a living biobank of patient-derived organoids of intraductal papillary mucinous neoplasms of the pancreas28
Mitochondrial dysfunction/NLRP3 inflammasome axis contributes to angiotensin II-induced skeletal muscle wasting via PPAR-γ28
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