Journal of Physiology-London

Article	Citations
Issue Information	135
In Memoriam: Ann Silver	121
Issue Information	108
Integrating respiration into sympathetic transduction to blood pressure	104
Issue Information	93
Decoding platelet loss in the hypoxic brain: What could go wrong?	82
CrossTalk rebuttal	80
Ocular surface information seen from the somatosensory thalamus and cortex	74
	64
Three‐dimensional printing of bioengineered scaffolds to support skeletal muscle regeneration	61
Semaglutide versus caloric restriction‐induced weight loss: insights into effects on skeletal muscle mass and function	58
Theoretical analysis of power‐law stress relaxation and calcium‐dependent passive mechanics in cardiac muscle	56
Action potentials in postganglionic sympathetic nerves depend on NaV1.7	55
Determinants and therapeutic potential of calcium handling abnormalities in atrial fibrillation: what can we learn from computer models?	55
Why you should pay more attention to your cells’ sex	53
The astrocytic Na+‐HCO3− cotransporter, NBCe1, is dispensable for respiratory chemosensitivity	53
Can heat stress augment the cerebrovascular and neurotrophic benefits of exercise?	52
Unveiling sex differences in skeletal muscle metabolism: the role of HIF1α in normoxia	51
Severe hypoxaemic hypercapnia compounds cerebral oxidative–nitrosative stress during extreme apnoea: Implications for cerebral bioenergetic function	51
Vasoactive signalling or vascular remodelling? Sex variances in mechanisms of cerebrovascular ageing	49
Metabolic adaptation without microbiome remodelling: Rethinking early host–microbiome dynamics	48
Breath taking fentanyl: how ether‐à‐go‐go potassium channels freeze your breath	46
Augmenting workload drives T‐tubule assembly in developing cardiomyocytes	46
Heartbeat‐related activity in the anterior thalamus differs between phasic and tonic REM sleep	45
High‐frequency electrical tuning and linear filter properties of Knollenorgan electroreceptors of mormyrid electric fish	45

Motor learning changes the axon initial segment of the spinal motoneuron	44
Peripheral chemoreflex restrains skeletal muscle blood flow during exercise in participants with treated hypertension	44
Cerebral uptake of microvesicles occurs in normocapnic but not hypocapnic passive hyperthermia in young healthy male adults	43
The 70‐year search for the voltage‐sensing mechanism of ion channels	42
Bayliss–Starling Prize Lecture: KATP channel pathophysiology – a whole‐body odyssey	42
Distinctive neurophysiological correlates of sound onset and offset perception in humans	42
Exciting roles of non‐excitable cells in the brain and heart	41
When the brain listens to the kidney, is it TRP'n or what?	41
Pregnancy does not affect progression of mild experimental asthma in sheep	41
How we deliver energy to the lung matters: Mechanistic clues for safer ventilation	40
Drafting the calmodulation playbook: Emerging structural insights into transient receptor potential channel regulation by calmodulin	40
Mitochondrial carbonic anhydrase VA and VB: properties and roles in health and disease	39
Engineering the immune and fibrotic response in VML	39
Corticothalamic modulation of somatosensory thalamic tactile processing	38
CKAMP44 controls synaptic function and strength of relay neurons during early development of the dorsal lateral geniculate nucleus	37
The impact of androgens on cardiovascular control mechanisms in polycystic ovary syndrome: Recent advances and translational approaches	37
Changes in intra‐ and interlimb reflexes from forelimb cutaneous afferents after staggered thoracic lateral hemisections during locomotion in cats	36
Lactate potentiates NMDA receptor currents via an intracellular redox mechanism targeting GluN2B subunits: implications for synaptic plasticity	36
Chronic intermittent hypoxia‐induced cardiovascular and renal dysfunction: from adaptation to maladaptation	36
PKMζ‐knockout mice lack neocortical long‐term potentiation: limits of hippocampal compensation and differential memory rescue	36
Reply to ‘Reevaluating central versus peripheral contributions to maximal oxygen uptake: the role of muscle diffusive capacity’	35
Angiotensin‐converting enzyme and exercise adaptations: Genetic variability, pharmacological modulation and future directions	34
Hypertension increases sympathetic neuron activity by enhancing intraganglionic cholinergic collateral connections	34
	33
Activation of the myosin motors in fast‐twitch muscle of the mouse is controlled by mechano‐sensing in the myosin filaments	33
Magnesium sulphate reduces tertiary gliosis but does not improve EEG recovery or white or grey matter cell survival after asphyxia in preterm fetal sheep	33
Goal‐directed action preparation in humans entails a mixture of corticospinal neural computations	33
Exercise training induces mitochondrial biogenesis, while high‐fat diet increases the ability of mitochondria to use long and short‐chain fatty acids	32
Opening the door to physiological impacts underlying opioid‐induced respiratory depression and therapeutic strategies: focus on fentanyl	32
Preferential lactate metabolism in the human brain during exogenous and endogenous hyperlactataemia	32
Maternal cardiometabolic dysfunction and fetal sex‐specific alterations to uterine vascular reactivity in an ovine model of obesity during pregnancy	32
Uncertainty quantification via polynomial chaos expansion of myocardial fibre orientation and cardiac activation patterns	32
LRRC8A‐containing anion channels promote glioblastoma proliferation via a WNK1/mTORC2‐dependent mechanism	31
‘Evolutionary poker’: an agent‐based model of interactome emergence and epistasis tested against Lenski's long‐term E. coli experiments	31
Mitochondrial haplotype and sex modulate responses to endurance exercise training	31
Lack of compensatory mitophagy in skeletal muscles during sepsis	30
Ventricular arrhythmogenic remodelling in diet‐induced metabolic syndrome driven by right‐to‐left regional differences in action potential duration and dominant frequency gradients	30
Issue Information	29
Stroke severity shapes extracellular vesicle profiles and their impact on the cerebral endothelial cells	29
Maternal obesity alters myeloid immune function in the offspring	29
Diversity of cells and signals in the cardiovascular system	29
Postexercise ketone supplementation: A new path to enhanced aerobic performance?	29
Issue Information	28
Issue Information	28
Muscle déjà vu: are myonuclei the blueprint for muscle regrowth?	28
An experiment of nature links muscle glycogen unavailability with very high fat oxidation rates despite low aerobic fitness	28
Response to ‘Comment on Wyrwoll et al., 2022: Long‐term exposure of mice to 890 ppm atmospheric CO2 alters growth trajectories and hyperactive behaviours in adults’ by Norman R. Saunders an	28
	27
The non‐invasive assessment of muscle fibre size: has the future arrived?	27
Making ‘sense’ of what happens on the inside: il‘LUMEN'ating the effects of intestinal distention on calcium activity in enteric neurons	27

Multispectral brain connectivity during visual attention distinguishes controlled from uncontrolled hypertension	27
Towards unravelling the exercise‐induced adaptations in circulating extracellular vesicles	27
Too hot to handle? Unveiling gut permeability during exertional heat stress	27
Ageing reduces persistent inward current contribution to motor neurone firing: Potential mechanisms and the role of exercise	27
Muscle matters: exploring the contributions of ageing skeletal muscle to metabolic syndrome	27
Situating physiology within evolutionary theory	27
Hypoxic sensitivity and burden predict propensity for respiratory plasticity in humans	26
The fallacy of functional nomenclature in the kingdom of biological multifunctionality: physiological and evolutionary considerations on ion channels	26
The potential therapeutic benefits of low frequency haemodynamic oscillations	26
Efficiency of cycling exercise: Understanding the physiology	26
Muscle memory theory: Implications for health, athletic performance and sports integrity	25
Microglial phagocytosis in epilepsy: Mechanisms and impact	25
The carotid body as a polymodal receptor and multisystem effector	25
Issue Information	25
From signals to systems: Mapping the complex physiology of cardiorespiratory dynamics with information theory	25
Advances in cardiac devices and bioelectronics augmented with artificial intelligence	25
Clenbuterol induces lean mass and muscle protein accretion, but attenuates cardiorespiratory fitness and desensitizes muscle β2‐adrenergic signalling	25
Synaptic loss in motor neurons precipitates age‐related dysphagia: Middle agers gotta keep in touch!	25
Volitional exercise elicits physiological and molecular improvements in the severe D2.mdx mouse model of Duchenne muscular dystrophy	25
Inhibitory circuit motifs of cortical somatosensory layer 5 SST interneurons are uniform within layers but specific across layers	25
Beyond the placenta: hepcidin as a hidden driver of fetal hypoxia in maternal obesity	25
Properties and modulation of excitatory inputs to the locus coeruleus	24
Fast and sensitive GCaMP calcium indicators for neuronal imaging	24
In vivo quantification of mitochondrial O 2 affinity in human skeletal muscle using 1	24
Action potential amplitude and baroreflex resetting of action potential clusters mediate hypoxia‐induced sympathetic long‐term facilitation	24
The diverse functions of the DEG/ENaC family: linking genetic and physiological insights	24
Corrigendum	24
Demonstration of beat‐to‐beat, on‐demand ATP synthesis in ventricular myocytes reveals sex‐specific mitochondrial and cytosolic dynamics	24
Inflammatory gene expression during acute high‐altitude exposure	24
Speciation by physiological selection of environmentally acquired traits	24
The neural control of movement: a century of in vivo motor unit recordings is the legacy of Adrian and Bronk	24
Presynaptic H 3 receptor: A modulator for CeL excitatory‐inhibitory homeostasis	24
Reply from J. E. Mallinson, D. Constantin‐Teodosiu, D. Constantin, M. V. Franchi and P. L. Greenhaff: NSAIDs and muscle hypertrophy – preconceptions and differing interpretations in the face of a pauc	24
Dietary nitrate supplementation improves age‐associated neuromuscular outcomes: A step towards healthy ageing	24
TMEM16A in gastrointestinal and vascular smooth muscle contractility	24
Multi‐scale modelling of the effects of ageing, hypertension and exercise on the cerebral vasculature	24
Loss of the alpha subunit distal furin cleavage site blunts ENaC activation following Na+ restriction	24
Extracellular vesicles and their non‐coding RNA cargos: Emerging players in cardiovascular disease	24
A cross‐species validation of single‐beat metrics of cardiac contractility	24
Hyperglycaemia, pregnancy outcomes and maternal metabolic disease risk during pregnancy and lactation in a lean gestational diabetes mouse model	24
The key to our hearts: Unlocking fundamental sex differences in mouse cardiomyocyte calcium‐cycling	23
A game of chest: Where does blood volume shift?	23
Cathodal bilateral transcranial direct‐current stimulation regulates selenium to confer neuroprotection after rat cerebral ischaemia–reperfusion injury	23
Optical mapping of contracting hearts	23
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Use it or lose it: protecting ageing muscles with lifelong recreational exercise	23
The benefits of being passive	23
Macrophage microvesicle‐derived circ_YTHDF2 in methamphetamine‐induced chronic lung injury	23
Thermodynamic limitations on brain oxygen metabolism: physiological implications*	23
Issue Information	23
Beeting atrophy: dietary nitrate to protect the powerhouse of the cell?	23
The pathological blood flow steal phenomenon limits exercise tolerance in pulmonary hypertensive rats	23
Neural Modulations during the Stretch–Shortening Cycle: The Importance of Movement Velocity and Task Specificity	23
Bioavailable testosterone and androgen receptor activation, but not total testosterone, are associated with muscle mass and strength in females	23
The effects of local vibration inducing a tonic vibration reflex or movement illusion on acute modulations of corticospinal excitability	22
Mechano‐electrical interactions and heterogeneities in wild‐type and drug‐induced long QT syndrome rabbits	22
Issue Information	22
Sarcolemmal and mitochondrial membrane potentials measured ex vivo and in vivo in the heart by pharmacokin	22
Circadian patterns of heart rate variability in fetal sheep after hypoxia‐ischaemia: A biomarker of evolving brain injury	22
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Transcranial photobiomodulation with near‐infrared laser induces analgesia in rats	22
Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners	22
Exercise intolerance in pulmonary hypertension: robbing Peter to pay Paul	22
Characterizing the effects of type I collagen alterations on respiratory function in mouse models with varying severity of osteogenesis imperfecta	21
Critical molecular outcomes of time‐restricted feeding during ageing: a look beyond body composition	21
Adrenergic restraint of blood flow and high‐altitude acclimatization	21
A detailed mathematical model of the human atrial cardiomyocyte: integration of electrophysiology and cardiomechanics	21
Astrocytes: Orchestrators of brain gas exchange and oxygen homeostasis	21
Whole‐body metabolic rate is influenced by muscle fibre typology	21
Pump up the volume: breathing facilitates cardiac output during exercise by mechanical action	21
The cardiac sodium channel from function to dysfunction	21
Crosstalk between biochemical signalling network architecture and trafficking governs AMPAR dynamics in synaptic plasticity	21
Regulation of basal and tumour necrosis factor α‐induced fibroblast gene expression by peptidylarginine deiminase 2	21
The complexity of Nrf2 in experimental autoimmune myositis‐induced mice	21
Flex and flow: are we receptive to all females in muscle physiology research?	21
Reorganization of mitochondria–organelle interactions during postnatal development in skeletal muscle	21
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Regional myosin mechanosensing dysfunction under metabolic stress	21
Adenine nucleotide translocator and ATP synthase cooperate in mediating the mitochondrial permeability transition	20
Respiratory control at high altitude: The chemoreceptor as a paragon of plasticity	20

Novel regenerative drug, SPG302 promotes functional recovery of diaphragm muscle activity after cervical spinal cord injury	20
Oncomodulin regulates spontaneous calcium signalling and maturation of afferent innervation in cochlear outer hair cells	20
CCK‐elicited pancreatic Ca 2+ signal generation is probably not initiated by IP 3 formation	20
Connexin 36‐mediated gap junctions contribute to fine odour discrimination and late‐phase excitation of mitral cells in the mouse olfactory bulb	20
Ketogenic diet and ketone salts differentially improve cardiometabolic complications in an HFpEF rat model	20
Intrinsic motoneuron properties in typical human development	20
An automated respiratory data pipeline for waveform characteristic analysis	20
An age‐associated decline in the role of the sarcoplasmic reticulum and associated calcium‐handling proteins sets the pace for sinoatrial node function	20
Reduced plakoglobin increases the risk of sodium current defects and atrial conduction abnormalities in response to androgenic anabolic steroid abuse	20
The time is now: regular exercise maintains vascular health in ageing women	20
CPT1C is required for synaptic plasticity and oscillatory activity that supports motor, associative and non‐associative learning	19
Pathogenic TNNT1 variants are associated with aberrant thin filament compliance and myofibre hyper‐contractility	19
Glyoxalase 1 overexpression improves neurovascular coupling and limits development of mild cognitive impairment in a mouse model of type 1 diabetes	19
Nav1.2 and BK channel interaction shapes the action potential in the axon initial segment	19
Issue Information	19
Development of striated muscle microvasculature across the perinatal period in lambs	19
Towards spatially selective efferent neuromodulation: anatomical and functional organization of cardiac fibres in the porcine cervical vagus nerve	19
Issue Information	19
Muscular strength, endothelial function and cognitive disorders: state of the art	19
Ageing impairs endothelium‐dependent vasodilatation and alters redox signalling in diaphragm arterioles from male and female Fischer‐344 rats	19
The post‐arteriole transitional zone: a specialized capillary region that regulates blood flow within the CNS microvasculature	19
Translating physiology of the arterial chemoreflex into novel therapeutic interventions targeting carotid bodies in cardiometabolic disorders	19
Central α2‐adrenergic mechanisms regulate human sympathetic neuronal discharge strategies	19
Metabolite‐sensitive cross‐bridge models of human atria reveal the impact of diabetes on muscle mechanoenergetics	19
Particle‐swarm based modelling reveals two distinct classes of CRH PVN neurons	19
A systematic review of computational models for the design of spinal cord stimulation therapies: from neural circuits to patient‐specific simulations	19
Issue Information	19
Beat‐to‐beat QT interval variability as a tool to detect the underlying cellular mechanisms of arrhythmias	19
TET2 confers a mechanistic link of microRNA‐210 and mtROS in hypoxia‐suppressed spontaneous transient outward currents in uterine arteries of pregnant sheep	19
Neurobiology of mitochondrial dynamics in sleep	19
Neuroinflammation and the immune system in hypoxic ischaemic brain injury pathophysiology after cardiac arrest	19
Issue Information	18
Becoming mindful of mindfulness: a promising approach to reducing sympathetic nervous system overactivity in chronic kidney disease	18
Symptom‐modifying strategy to treat upper respiratory tract infections: a clinical and mechanistic evidence of ColdZyme	18
Rebuttal from Amy Richardson and Gareth Morris	18
Issue Information	18
Age‐related diaphragm dysfunction: could diaphragm arteriole dysfunction be to blame?	18
Fasting and the short‐term consumption of a ketogenic diet are sufficient interventions to protect against OLZ‐induced hyperglycaemia in mice	18
Exercise affects fatty acid oxidation and lipid droplets in patients with type 2 diabetes	18
Muscle–fat crosstalk: effects of exercise on brown adipose tissue; what do we know?	18
Issue Information	18
Untangling age and menopause: vascular mechanisms for cardiovascular disease risk in females	18
Vaping for two: unravelling the mysteries of E‐cigarettes and fetal vascular health	18
What is fetal growth restriction and how might we know?	18
Expiratory flow limitation during exercise: why does it ‘suck’ so much?	18
Cardiac programming in the placentally restricted sheep fetus in early gestation	17
Directional sensitivity of C‐low‐threshold mechanoreceptors: insights from in vivo calcium imaging	17
Correction to ‘A single bout of prior resistance exercise attenuates muscle atrophy and declines in myofibrillar protein synthesis during bed‐rest in older men’	17
Exercise‐induced arterial hypoxaemia in patients with heart failure with preserved ejection fraction	17
History bias and its perturbation of the stimulus representation in the macaque prefrontal cortex	17
Transient capacitance changes recorded from vestibular type I hair cells are produced by GK,L gating and do not involve neurotransmitter exocytosis	17
Stepping up to inspire in muscular dystrophy	17
Loss of anoctamin 1 reveals a subtle role for BK channels in lymphatic muscle action potentials	17
Autonomic modulation with mindfulness‐based stress reduction in chronic kidney disease: a randomized controlled trial	17
Clarifying power‐mediated aerosol effects and enhancing statistical rigor in in utero E‐cigarette exposure research	17
High altitude differentially modulates potassium channel‐evoked vasodilatation in pregnant human myometrial arteries	17
Beyond the madness: a balanced approach to standardization, practicality and innovation in exercise physiology threshold assessment	17
Persistent hypoxia after birth limits cerebrovascular myogenic and autoregulatory capacity when oxygenation is restored	17
Mechanical sensitization of sensory afferents after passive transfer of fibromyalgia IgG	17
Chemoreflex function in pulmonary diseases – A review	17
Now and then: Development of spinal Shox2 neurons	16
The complex function of macrophages and their subpopulations in metabolic injury associated fatty liver disease	16
Enter Sandman: An eye opening opinion of cardiovascular disease prevention in cervical spinal cord injury	16
Presynaptic quantal size enhancement counteracts post‐tetanic release depression	16
Ubiquitin ligase signalling networks shape presynaptic development, function and disease	16
‘Mini analysis’ misrepresents changes in synaptic properties due to incomplete event detection	16
Atypical delayed paired‐pulse depression at an identified synapse	16
Annual Prize Lecture 2024: Endogenous physiological mechanisms as basis for the treatment of obesity and type 2 diabetes	16
Fluorescent biosensor imaging meets deterministic mathematical modelling: quantitative investigation of signalling compartmentalization	16
Deficiency of PKA‐mediated SNAP‐25b phosphorylation destabilizes exocytotic fusion pores and reduces the interactions of t‐SNAREs	16
Homeostasis and evolution in relation to regeneration and repair	16
Activation of TRPA1 and TRPM3 triggers Ca 2+ waves in central terminals of sensory neurons and facilitates synaptic activity in the spinal dorsal hor	16
Can muscle typology explain the inter‐individual variability in resistance training adaptations?	16
Scale‐invariant changes in corticospinal excitability reflect multiplexed oscillations in the motor output	16
State‐dependent neural representations of muscle synergies in the spinal cord revealed by optogenetic stimulation	16
Moderate nutrient restriction dysregulates molecular markers of calcium handling in the left ventricle of the non‐human primate fetal heart	16
Ageing‐induced weakness of mouse NMJs is associated with reduced active zone density, synaptic event kinetics and presynaptic calcium entry	16
Myosin motor dynamics and cardiac function: Insights from in vivo small‐angle X‐ray scattering and pressure–volume analysis	16
Muscle‐derived IL‐1β regulates EcSOD expression via the NBR1‐p62‐Nrf2 pathway in muscle during cancer cachexia	16
Endurance training increases a ubiquitylated form of histone H3 in the skeletal muscle, supporting Notch1 upregulation in an MDM2‐dependent manner	15
Cross Talk proposal: Human‐derived brain tissue is a better epilepsy model than animal‐based approaches	15
Issue Information	15
Distinct distributions of myosin motor conformations during contraction of slow and fast skeletal muscle	15
Paraventricular nucleus projections to the nucleus tractus solitarii are essential for full expression of hypoxia‐induced peripheral chemoreflex responses	15
The repair capacity spectrum of human skeletal muscle injury from sports to surgical trauma settings	15
The cardiac pacemakers: A paradigm of robustness in evolutionary biology	15
Plasma measurements of the dual sugar test reveal carbohydrate immediately alleviates intestinal permeability caused by exertional heat stress	15
Recurrence of ventricular fibrillation in out‐of‐hospital cardiac arrest: Clinical evidence and underlying ionic mechanisms	15
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Interstitial cells of Cajal – pacemakers of the gastrointestinal tract	15
Enhancing stroke risk stratification in atrial fibrillation through non‐Newtonian blood modelling and Gaussian process emulation	15
Hypoxia and hypercapnia elicit overlapping but distinct skeletal muscle toxicities	15
Machine‐learning classification of motor unit types in the adult mouse	15
Endurance exercise training changes the limitation on muscle V̇O2max${\dot{V}}_{{{\mathrm{O}}}_{\mathrm{2}}{\mathrm{max}}}$ in normoxia from the capacity to utilize O2 to the capacity to tr	15
Stem cell approaches for tendon repair: delusion or insight	15