Journal of Physiology-London

Article	Citations
Issue Information	145
In Memoriam: Ann Silver	129
Issue Information	128
Integrating respiration into sympathetic transduction to blood pressure	125
Issue Information	109
Decoding platelet loss in the hypoxic brain: What could go wrong?	90
CrossTalk rebuttal	77
Ocular surface information seen from the somatosensory thalamus and cortex	66
	63
Semaglutide versus caloric restriction‐induced weight loss: insights into effects on skeletal muscle mass and function	62
Determinants and therapeutic potential of calcium handling abnormalities in atrial fibrillation: what can we learn from computer models?	61
Action potentials in postganglionic sympathetic nerves depend on NaV1.7	59
Why you should pay more attention to your cells’ sex	58
The astrocytic Na+‐HCO3− cotransporter, NBCe1, is dispensable for respiratory chemosensitivity	58
Can heat stress augment the cerebrovascular and neurotrophic benefits of exercise?	57
Severe hypoxaemic hypercapnia compounds cerebral oxidative–nitrosative stress during extreme apnoea: Implications for cerebral bioenergetic function	54
Unveiling sex differences in skeletal muscle metabolism: the role of HIF1α in normoxia	53
Vasoactive signalling or vascular remodelling? Sex variances in mechanisms of cerebrovascular ageing	52
Metabolic adaptation without microbiome remodelling: Rethinking early host–microbiome dynamics	51
Breath taking fentanyl: how ether‐à‐go‐go potassium channels freeze your breath	51
High‐frequency electrical tuning and linear filter properties of Knollenorgan electroreceptors of mormyrid electric fish	49
Peripheral chemoreflex restrains skeletal muscle blood flow during exercise in participants with treated hypertension	48
Cerebral uptake of microvesicles occurs in normocapnic but not hypocapnic passive hyperthermia in young healthy male adults	46
Postexercise ketone supplementation: A new path to enhanced aerobic performance?	45
Activation of the myosin motors in fast‐twitch muscle of the mouse is controlled by mechano‐sensing in the myosin filaments	45

Angiotensin‐converting enzyme and exercise adaptations: Genetic variability, pharmacological modulation and future directions	45
Exciting roles of non‐excitable cells in the brain and heart	44
Bayliss–Starling Prize Lecture: KATP channel pathophysiology – a whole‐body odyssey	44
Pregnancy does not affect progression of mild experimental asthma in sheep	44
Distinctive neurophysiological correlates of sound onset and offset perception in humans	44
Drafting the calmodulation playbook: Emerging structural insights into transient receptor potential channel regulation by calmodulin	44
Reply to ‘Reevaluating central versus peripheral contributions to maximal oxygen uptake: the role of muscle diffusive capacity’	43
Changes in intra‐ and interlimb reflexes from forelimb cutaneous afferents after staggered thoracic lateral hemisections during locomotion in cats	43
Hypertension increases sympathetic neuron activity by enhancing intraganglionic cholinergic collateral connections	42
Mitochondrial haplotype and sex modulate responses to endurance exercise training	40
Opening the door to physiological impacts underlying opioid‐induced respiratory depression and therapeutic strategies: focus on fentanyl	40
Preeclampsia‐derived small extracellular vesicles disrupt blood–brain barrier integrity and activate glial cells in vitro	40
‘Evolutionary poker’: an agent‐based model of interactome emergence and epistasis tested against Lenski's long‐term E. coli experiments	38
Maternal cardiometabolic dysfunction and fetal sex‐specific alterations to uterine vascular reactivity in an ovine model of obesity during pregnancy	38
Theoretical analysis of power‐law stress relaxation and calcium‐dependent passive mechanics in cardiac muscle	38
Stroke severity shapes extracellular vesicle profiles and their impact on the cerebral endothelial cells	38
Uncertainty quantification via polynomial chaos expansion of myocardial fibre orientation and cardiac activation patterns	37
When the brain listens to the kidney, is it TRP'n or what?	37
Goal‐directed action preparation in humans entails a mixture of corticospinal neural computations	35
	35
Augmenting workload drives T‐tubule assembly in developing cardiomyocytes	35
How we deliver energy to the lung matters: Mechanistic clues for safer ventilation	35
Motor learning changes the axon initial segment of the spinal motoneuron	34
PKMζ‐knockout mice lack neocortical long‐term potentiation: limits of hippocampal compensation and differential memory rescue	34
Publish or perish, but at what cost?	34
Engineering the immune and fibrotic response in VML	34
Three‐dimensional printing of bioengineered scaffolds to support skeletal muscle regeneration	34
Exercise training induces mitochondrial biogenesis, while high‐fat diet increases the ability of mitochondria to use long and short‐chain fatty acids	33
The interplay between dynamic regulation of ion‐channel gating and trafficking in cardiac arrhythmogenesis	33
The impact of androgens on cardiovascular control mechanisms in polycystic ovary syndrome: Recent advances and translational approaches	32
Heartbeat‐related activity in the anterior thalamus differs between phasic and tonic REM sleep	32
Lactate potentiates NMDA receptor currents via an intracellular redox mechanism targeting GluN2B subunits: implications for synaptic plasticity	32
Preferential lactate metabolism in the human brain during exogenous and endogenous hyperlactataemia	32
Ventricular arrhythmogenic remodelling in diet‐induced metabolic syndrome driven by right‐to‐left regional differences in action potential duration and dominant frequency gradients	32
Mitochondrial carbonic anhydrase VA and VB: properties and roles in health and disease	32
Lack of compensatory mitophagy in skeletal muscles during sepsis	31
Chronic intermittent hypoxia‐induced cardiovascular and renal dysfunction: from adaptation to maladaptation	31
Short‐changed: Limited short‐chain fatty acid oxidative capacity in skeletal muscle mitochondria	31
Corticothalamic modulation of somatosensory thalamic tactile processing	31
LRRC8A‐containing anion channels promote glioblastoma proliferation via a WNK1/mTORC2‐dependent mechanism	31
Magnesium sulphate reduces tertiary gliosis but does not improve EEG recovery or white or grey matter cell survival after asphyxia in preterm fetal sheep	31
Brain sparing in fetal growth restriction: The double‐edged sword of fetal hypoxaemia	31
Issue Information	30
Response to ‘Comment on Wyrwoll et al., 2022: Long‐term exposure of mice to 890 ppm atmospheric CO2 alters growth trajectories and hyperactive behaviours in adults’ by Norman R. Saunders an	30
Maternal obesity alters myeloid immune function in the offspring	30
Diversity of cells and signals in the cardiovascular system	30
Issue Information	30
Issue Information	30
An experiment of nature links muscle glycogen unavailability with very high fat oxidation rates despite low aerobic fitness	30
Towards unravelling the exercise‐induced adaptations in circulating extracellular vesicles	29

Muscle déjà vu: are myonuclei the blueprint for muscle regrowth?	29
The non‐invasive assessment of muscle fibre size: has the future arrived?	29
Too hot to handle? Unveiling gut permeability during exertional heat stress	29
Making ‘sense’ of what happens on the inside: il‘LUMEN'ating the effects of intestinal distention on calcium activity in enteric neurons	29
Muscle matters: exploring the contributions of ageing skeletal muscle to metabolic syndrome	29
	29
From signals to systems: Mapping the complex physiology of cardiorespiratory dynamics with information theory	28
The carotid body as a polymodal receptor and multisystem effector	28
Issue Information	28
Hypoxic sensitivity and burden predict propensity for respiratory plasticity in humans	28
Synaptic loss in motor neurons precipitates age‐related dysphagia: Middle agers gotta keep in touch!	28
Beyond the placenta: hepcidin as a hidden driver of fetal hypoxia in maternal obesity	28
Multispectral brain connectivity during visual attention distinguishes controlled from uncontrolled hypertension	28
Muscle memory theory: Implications for health, athletic performance and sports integrity	28
Properties and modulation of excitatory inputs to the locus coeruleus	27
A cross‐species validation of single‐beat metrics of cardiac contractility	27
Multi‐scale modelling of the effects of ageing, hypertension and exercise on the cerebral vasculature	27
Demonstration of beat‐to‐beat, on‐demand ATP synthesis in ventricular myocytes reveals sex‐specific mitochondrial and cytosolic dynamics	27
Reply from J. E. Mallinson, D. Constantin‐Teodosiu, D. Constantin, M. V. Franchi and P. L. Greenhaff: NSAIDs and muscle hypertrophy – preconceptions and differing interpretations in the face of a pauc	27
Loss of the alpha subunit distal furin cleavage site blunts ENaC activation following Na+ restriction	27
Presynaptic H 3 receptor: A modulator for CeL excitatory‐inhibitory homeostasis	27
Hyperglycaemia, pregnancy outcomes and maternal metabolic disease risk during pregnancy and lactation in a lean gestational diabetes mouse model	26
Clenbuterol induces lean mass and muscle protein accretion, but attenuates cardiorespiratory fitness and desensitizes muscle β2‐adrenergic signalling	26
In vivo quantification of mitochondrial O 2 affinity in human skeletal muscle using 1	26
Corrigendum	26
Macrophage microvesicle‐derived circ_YTHDF2 in methamphetamine‐induced chronic lung injury	26
The potential therapeutic benefits of low frequency haemodynamic oscillations	26
Dietary nitrate supplementation improves age‐associated neuromuscular outcomes: A step towards healthy ageing	26
Neural Modulations during the Stretch–Shortening Cycle: The Importance of Movement Velocity and Task Specificity	26
The diverse functions of the DEG/ENaC family: linking genetic and physiological insights	26
Volitional exercise elicits physiological and molecular improvements in the severe D2.mdx mouse model of Duchenne muscular dystrophy	25
Thermodynamic limitations on brain oxygen metabolism: physiological implications*	25
Situating physiology within evolutionary theory	25
Optical mapping of contracting hearts	25
Inhibitory circuit motifs of cortical somatosensory layer 5 SST interneurons are uniform within layers but specific across layers	25
Cathodal bilateral transcranial direct‐current stimulation regulates selenium to confer neuroprotection after rat cerebral ischaemia–reperfusion injury	25
Inflammatory gene expression during acute high‐altitude exposure	25
The physiology of feeling: C‐tactile afferents scaffold the developing social brain?	25
Efficiency of cycling exercise: Understanding the physiology	25
Advances in cardiac devices and bioelectronics augmented with artificial intelligence	25
Microglial phagocytosis in epilepsy: Mechanisms and impact	25
Extracellular vesicles and their non‐coding RNA cargos: Emerging players in cardiovascular disease	25
Bioavailable testosterone and androgen receptor activation, but not total testosterone, are associated with muscle mass and strength in females	24
The neural control of movement: a century of in vivo motor unit recordings is the legacy of Adrian and Bronk	24
TMEM16A in gastrointestinal and vascular smooth muscle contractility	24
Speciation by physiological selection of environmentally acquired traits	24
Ageing reduces persistent inward current contribution to motor neurone firing: Potential mechanisms and the role of exercise	24
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Glutamatergic modulation of transcranial direct current stimulation over the premotor cortex combined with peripheral nerve stimulation promotes observation–execution‐related cortical excitability and	24
Fast and sensitive GCaMP calcium indicators for neuronal imaging	24
Isometric slow‐ and fast‐contracting skeletal muscle fibres have more similar cellular and molecular properties at 37°C than at 25°C in older adults	24
The fallacy of functional nomenclature in the kingdom of biological multifunctionality: physiological and evolutionary considerations on ion channels	24
Issue Information	23
A game of chest: Where does blood volume shift?	23
Exercise intolerance in pulmonary hypertension: robbing Peter to pay Paul	23
Crosstalk between biochemical signalling network architecture and trafficking governs AMPAR dynamics in synaptic plasticity	23
Metabolite‐sensitive cross‐bridge models of human atria reveal the impact of diabetes on muscle mechanoenergetics	23
Connexin 36‐mediated gap junctions contribute to fine odour discrimination and late‐phase excitation of mitral cells in the mouse olfactory bulb	23
Muscular strength, endothelial function and cognitive disorders: state of the art	23
Issue Information	23
The key to our hearts: Unlocking fundamental sex differences in mouse cardiomyocyte calcium‐cycling	23
Issue Information	23
Astrocytes: Orchestrators of brain gas exchange and oxygen homeostasis	23
The post‐arteriole transitional zone: a specialized capillary region that regulates blood flow within the CNS microvasculature	23
A systematic review of computational models for the design of spinal cord stimulation therapies: from neural circuits to patient‐specific simulations	23
CPT1C is required for synaptic plasticity and oscillatory activity that supports motor, associative and non‐associative learning	23
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Beeting atrophy: dietary nitrate to protect the powerhouse of the cell?	23
Decoding the molecular memory of obesity using machine learning and microRNA dynamics	23
Transcranial photobiomodulation with near‐infrared laser induces analgesia in rats	23
Critical molecular outcomes of time‐restricted feeding during ageing: a look beyond body composition	22
Pump up the volume: breathing facilitates cardiac output during exercise by mechanical action	22
Characterizing the effects of type I collagen alterations on respiratory function in mouse models with varying severity of osteogenesis imperfecta	22
The benefits of being passive	22
Adrenergic restraint of blood flow and high‐altitude acclimatization	22
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Whole‐body metabolic rate is influenced by muscle fibre typology	22
The complexity of Nrf2 in experimental autoimmune myositis‐induced mice	22
Mechano‐electrical interactions and heterogeneities in wild‐type and drug‐induced long QT syndrome rabbits	22
CCK‐elicited pancreatic Ca 2+ signal generation is probably not initiated by IP 3 formation	21

An automated respiratory data pipeline for waveform characteristic analysis	21
Nav1.2 and BK channel interaction shapes the action potential in the axon initial segment	21
A detailed mathematical model of the human atrial cardiomyocyte: integration of electrophysiology and cardiomechanics	21
Development of striated muscle microvasculature across the perinatal period in lambs	21
Regulation of basal and tumour necrosis factor α‐induced fibroblast gene expression by peptidylarginine deiminase 2	21
Respiratory control at high altitude: The chemoreceptor as a paragon of plasticity	21
Reduced plakoglobin increases the risk of sodium current defects and atrial conduction abnormalities in response to androgenic anabolic steroid abuse	21
Coordinated regulation of PIEZO2 by alternative splicing, post‐translational modification, membrane trafficking and protein partners	21
TET2 confers a mechanistic link of microRNA‐210 and mtROS in hypoxia‐suppressed spontaneous transient outward currents in uterine arteries of pregnant sheep	21
An age‐associated decline in the role of the sarcoplasmic reticulum and associated calcium‐handling proteins sets the pace for sinoatrial node function	21
The time is now: regular exercise maintains vascular health in ageing women	21
Particle‐swarm based modelling reveals two distinct classes of CRH PVN neurons	21
Sarcolemmal and mitochondrial membrane potentials measured ex vivo and in vivo in the heart by pharmacokin	21
Glyoxalase 1 overexpression improves neurovascular coupling and limits development of mild cognitive impairment in a mouse model of type 1 diabetes	21
Pathogenic TNNT1 variants are associated with aberrant thin filament compliance and myofibre hyper‐contractility	20
Intrinsic motoneuron properties in typical human development	20
Beat‐to‐beat QT interval variability as a tool to detect the underlying cellular mechanisms of arrhythmias	20
The pathological blood flow steal phenomenon limits exercise tolerance in pulmonary hypertensive rats	20
Transcranial direct current stimulation enhances delayed retention after 5 days of lower‐limb motor skill learning	20
The influence of metaboreflex activation on pulmonary pressure with combined chemoreflex activation in acute and chronic hypoxia	20
Oncomodulin regulates spontaneous calcium signalling and maturation of afferent innervation in cochlear outer hair cells	20
Neurobiology of mitochondrial dynamics in sleep	20
Flex and flow: are we receptive to all females in muscle physiology research?	20
Towards spatially selective efferent neuromodulation: anatomical and functional organization of cardiac fibres in the porcine cervical vagus nerve	20
Novel regenerative drug, SPG302 promotes functional recovery of diaphragm muscle activity after cervical spinal cord injury	20
Reorganization of mitochondria–organelle interactions during postnatal development in skeletal muscle	20
Ageing impairs endothelium‐dependent vasodilatation and alters redox signalling in diaphragm arterioles from male and female Fischer‐344 rats	20
Neuroinflammation and the immune system in hypoxic ischaemic brain injury pathophysiology after cardiac arrest	20
Translating physiology of the arterial chemoreflex into novel therapeutic interventions targeting carotid bodies in cardiometabolic disorders	20
Adenine nucleotide translocator and ATP synthase cooperate in mediating the mitochondrial permeability transition	20
The effects of local vibration inducing a tonic vibration reflex or movement illusion on acute modulations of corticospinal excitability	19
Regional myosin mechanosensing dysfunction under metabolic stress	19
Issue Information	19
Untangling age and menopause: vascular mechanisms for cardiovascular disease risk in females	19
The cardiac sodium channel from function to dysfunction	19
Circadian patterns of heart rate variability in fetal sheep after hypoxia‐ischaemia: A biomarker of evolving brain injury	19
Central α2‐adrenergic mechanisms regulate human sympathetic neuronal discharge strategies	19
Issue Information	19
Becoming mindful of mindfulness: a promising approach to reducing sympathetic nervous system overactivity in chronic kidney disease	19
Correction to ‘Shaping smell: Chloride currents dictate the kinetics of olfactory transduction’	19
Ketogenic diet and ketone salts differentially improve cardiometabolic complications in an HFpEF rat model	19
Issue Information	19
Age‐related diaphragm dysfunction: could diaphragm arteriole dysfunction be to blame?	19
Issue Information	19
Vaping for two: unravelling the mysteries of E‐cigarettes and fetal vascular health	18
Beyond the madness: a balanced approach to standardization, practicality and innovation in exercise physiology threshold assessment	18
Exercise‐induced arterial hypoxaemia in patients with heart failure with preserved ejection fraction	18
Transient capacitance changes recorded from vestibular type I hair cells are produced by GK,L gating and do not involve neurotransmitter exocytosis	18
Symptom‐modifying strategy to treat upper respiratory tract infections: a clinical and mechanistic evidence of ColdZyme	18
Rebuttal from Amy Richardson and Gareth Morris	18
Directional sensitivity of C‐low‐threshold mechanoreceptors: insights from in vivo calcium imaging	18
Correction to ‘A single bout of prior resistance exercise attenuates muscle atrophy and declines in myofibrillar protein synthesis during bed‐rest in older men’	18
History bias and its perturbation of the stimulus representation in the macaque prefrontal cortex	18
Exercise affects fatty acid oxidation and lipid droplets in patients with type 2 diabetes	18
Muscle–fat crosstalk: effects of exercise on brown adipose tissue; what do we know?	18
Stepping up to inspire in muscular dystrophy	18
Persistent hypoxia after birth limits cerebrovascular myogenic and autoregulatory capacity when oxygenation is restored	18
Clarifying power‐mediated aerosol effects and enhancing statistical rigor in in utero E‐cigarette exposure research	18
Expiratory flow limitation during exercise: why does it ‘suck’ so much?	18
What is fetal growth restriction and how might we know?	18
Ageing‐induced weakness of mouse NMJs is associated with reduced active zone density, synaptic event kinetics and presynaptic calcium entry	17
Now and then: Development of spinal Shox2 neurons	17
The complex function of macrophages and their subpopulations in metabolic injury associated fatty liver disease	17
Fluorescent biosensor imaging meets deterministic mathematical modelling: quantitative investigation of signalling compartmentalization	17
Deficiency of PKA‐mediated SNAP‐25b phosphorylation destabilizes exocytotic fusion pores and reduces the interactions of t‐SNAREs	17
Cross Talk proposal: Human‐derived brain tissue is a better epilepsy model than animal‐based approaches	17
High altitude differentially modulates potassium channel‐evoked vasodilatation in pregnant human myometrial arteries	17
Atypical delayed paired‐pulse depression at an identified synapse	17
State‐dependent neural representations of muscle synergies in the spinal cord revealed by optogenetic stimulation	17
Enter Sandman: An eye opening opinion of cardiovascular disease prevention in cervical spinal cord injury	17
Ubiquitin ligase signalling networks shape presynaptic development, function and disease	17
Stem cell approaches for tendon repair: delusion or insight	17
Cardiac programming in the placentally restricted sheep fetus in early gestation	17
Annual Prize Lecture 2024: Endogenous physiological mechanisms as basis for the treatment of obesity and type 2 diabetes	17
Vascular smooth muscle cell mechanotransduction: Pathways, phenotypes and emerging technologies	17
Presynaptic quantal size enhancement counteracts post‐tetanic release depression	17
Recurrence of ventricular fibrillation in out‐of‐hospital cardiac arrest: Clinical evidence and underlying ionic mechanisms	17
Autonomic modulation with mindfulness‐based stress reduction in chronic kidney disease: a randomized controlled trial	16
‘Mini analysis’ misrepresents changes in synaptic properties due to incomplete event detection	16
Endurance exercise training changes the limitation on muscle V̇O2max${\dot{V}}_{{{\mathrm{O}}}_{\mathrm{2}}{\mathrm{max}}}$ in normoxia from the capacity to utilize O2 to the capacity to tr	16
Neural coordination of bilateral hand movements: evidence for an involvement of brainstem motor centres	16
Enhancing stroke risk stratification in atrial fibrillation through non‐Newtonian blood modelling and Gaussian process emulation	16
Moderate nutrient restriction dysregulates molecular markers of calcium handling in the left ventricle of the non‐human primate fetal heart	16
Chemoreflex function in pulmonary diseases – A review	16
Scale‐invariant changes in corticospinal excitability reflect multiplexed oscillations in the motor output	16
Impaired skeletal muscle recovery: Immune cell dynamics across age and sex	16
Hypoxia and hypercapnia elicit overlapping but distinct skeletal muscle toxicities	16
Loss of anoctamin 1 reveals a subtle role for BK channels in lymphatic muscle action potentials	16
Paraventricular nucleus projections to the nucleus tractus solitarii are essential for full expression of hypoxia‐induced peripheral chemoreflex responses	16
A multimodal exercise countermeasure prevents the negative impact of head‐down tilt bed rest on muscle volume and mitochondrial health in older adults	16
Evolution of rod bipolar cells and rod vision	16
Muscle‐derived IL‐1β regulates EcSOD expression via the NBR1‐p62‐Nrf2 pathway in muscle during cancer cachexia	16
Sex‐dependent activation of apamin‐sensitive small‐conductance Ca 2+ ‐activated K + current by β1‐	16
Machine‐learning classification of motor unit types in the adult mouse	16
Homeostasis and evolution in relation to regeneration and repair	16