Journal of Pharmacy and Pharmacology

Article	Citations
Tilianin obtained from Agastache mexicana inhibits monoamine oxidase and modifies depressive behavior in rats	84
Study on the targeted regulation of Scutellaria baicalensis leaf on glutamine–glutamate metabolism and glutathione synthesis in the liver of d-gal ageing rats	82
Photoactivation of pheophorbide-a utilizing 670 nm LEDs elicits cancer suppressive effects in androgen-independent prostate cancer cellular models	49
3-Demethyl-2-geranyl-4-prenylbellidifoline, a natural xanthone with diuretic and kidney protective properties	48
GL-V9 synergizes with oxaliplatin of colorectal cancer via Wee1 degradation mediated by HSP90 inhibition	47
A comprehensive review of traditional uses, phytochemistry and pharmacology of Reynoutria genus	39
Oleanolic acid ameliorates podocyte injury by increasing autophagy to attenuate diabetic nephropathy	37
Inhibition of human ether-à-go-go-related gene K+ currents expressed in HEK293 cells by three gingerol components from ginger	35
Exploring the potential of vaginal drug delivery: innovations, efficacy, and therapeutic prospects	35
Δ(9)-tetrahydrocannabinol protects cardiac tissue against endoplasmic reticulum and oxidative stresses, apoptosis, and inflammation in rats with hyperinsulinemia	35
Serum autotaxin level: a promising diagnostic biomarker in differentiating Graves’ disease and thyroiditis	31
Erythrocyte membrane-camouflaged mesoporous silica composite nanoparticles for loading and controlled release of the hepatoprotective agent silibinin: A-synthesis and physicochemical characterization	30
Eleutheroside E functions as anti-cervical cancer drug by inhibiting the phosphatidylinositol 3-kinase pathway and reprogramming the metabolic responses	29
Ginsenoside Rb1 ameliorates hippocampal neuroinflammation in rats after intracerebral hemorrhage by inactivating the TLR4/NF-kB pathway	28
PI3K/AKT/Nrf2 signalling pathway is involved in the ameliorative effects of xanthohumol on amyloid β-induced oxidative damage and bone loss	28
Ending nuclear weapons, before they end us	27
Preparation, characteristic, biological activities, and application of polysaccharide from Lilii Bulbus: a review	26
Rhamnetin: a review of its pharmacology and toxicity	26
Roles of pigment epithelium-derived factor in cardiomyocytes: implications for use as a cardioprotective therapeutic	26
Protective effect of Allium scorodoprasum L. ethanolic extract in cyclophosphamide-induced hepatotoxicity model in rats	26
Thyme extract could overcome diabetes-induced reproductive dysfunction by inhibiting oxidative damage and increasing the expression of insulin receptor substrate and pyruvate kinase in the rat sperm	26
Ling-Gui-Zhu-Gan decoction protects against doxorubicin-induced myocardial injury by downregulating ferroptosis	26
The therapeutic potential of curculigoside in poststroke depression: a focus on hippocampal neurogenesis and mitochondrial function	25
The pleiotropic effects of statins in rheumatoid arthritis	25
Wei-Tong-Xin exerts anti-inflammatory effects through TLR4-mediated macrophages M1/M2 polarization and affects GLP-1 secretion	24

Production of mRNA lipid nanoparticles using advanced crossflow micromixing	24
Evaluating the role of bromelain in diabetes management: a systematic review of research evidence and mechanisms of action	23
Phytochemical study and immunomodulatory activity of Fraxinus excelsior L.	22
LINC01572 promotes the malignant progression of lung adenocarcinoma by modulating p53 mediated by miRNA-338-5p/TTK axis	22
Validating the antidiabetic potential of Nakima (Tupistra clarkei Hook.f.), a traditional food from eastern Himalayan region, through network pharmacology and in vivo experimentation	22
Dexmedetomidine affects the NOX4/Nrf2 pathway to improve renal antioxidant capacity	21
Dendrophenol attenuates cardiac hypertrophy through inhibition of ferroptosis via the C-Jun/NCOA4 signaling pathway	21
N(Omega)-nitro-l-arginine methyl ester potentiates lidocaine analgesic and anaesthetic effect in rats	20
Therapeutically important bioactive compounds of the genus Polygonum L. and their possible interventions in clinical medicine	20
Cardioprotection of Eucommiae Folium: the extract and pharmaceutically active compounds attenuate hyperglycemia, mitochondrial dysfunction, calcium dyshomeostasis, insulin resistance, and oxidative st	20
Repurposing the familiar: Future treatment options against chronic kidney disease	20
Circular RNA hsa_circ_0026344 suppresses gastric cancer cell proliferation, migration and invasion via the miR-590-5p/PDCD4 axis	20
The effect of patient’s body weight, infusion connection point, and infusion pump position on intravenous multi-infusion drug delivery at low infusion rates suitable for premature neonates	20
Traditional uses, hepatoprotective potential, and phytopharmacology of Tinospora cordifolia: a narrative review	20
Three-dimensional printed personalized drug devices with anatomical fit: a review	19
Function and inhibition of Haspin kinase: targeting multiple cancer therapies by antimitosis	19
Correction to: FoxO1 as the critical target of puerarin to inhibit osteoclastogenesis and bone resorption	19
In vitro assessment of P-glycoprotein-mediated antiseizure medications efflux in a blood–brain barrier cell model	19
Scopoletin stimulates the secretion of insulin via a KATP channel-dependent pathway in INS-1 pancreatic β cells	19
Icariside II: natural occurrence, biotransformation, pharmacological activity, synthetic modification, pharmacokinetics, and bioavailability	19
Therapeutic effects of Tanshinone IIA and Tetramethylpyrazine nanoemulsions on cognitive impairment and neuronal damage in Alzheimer’s disease rat models	18
Shaoyao Gancao decoction, an Ancient Classical Prescription: a review on its chemical composition, pharmacology, pharmacokinetics, clinical applications, and toxicology	18
Itrifal-e-Aftimoon potentiates imatinib-induced anti-leukemic effect by influencing FAK/STAT/Akt/ERK signalling pathways against chronic myeloid leukaemia in vitro	18
Investigation of the effect of Acai berry on the pharmacokinetics of Atorvastatin, Alogliptin and Empagliflozin: a herb–drug interaction study	17
Exploring the combined therapeutic efficacy of bexarotene and icariin in type 2 diabetic rats	17
Molecular mechanisms of endoplasmic reticulum stress-mediated acute kidney injury in juvenile rats and the protective role of mesencephalic astrocyte-derived neurotrophic factor	17
The potential applications of nanocomposites in 3D-printed drug delivery systems	17
Research progress on pharmacological effects of isoalantolactone	17
Systems pharmacology-based drug discovery from Amaryllidaceae alkaloids and investigation of mechanisms of action in treatment of Alzheimer’s disease	16
Thymol suppressed tumor growth in vitro and in vivo through inducing calcium overload in colorectal cancer	16
Correction to: 1H-NMR-based metabolomics to dissect the traditional Chinese medicine promotes mesenchymal stem cell homing as intervention in liver fibrosis in mouse model of Wilson’s disease	16
Botany, traditional uses, phytochemistry, pharmacological and toxicological effects of Croton tiglium Linn.: a comprehensive review	16
Evaluation of methotrexate-loaded surfactants, ceramides and cholesterol-based lamellar phases as a topical treatment for psoriasis	16
The genus Oxytropis DC: application, phytochemistry, pharmacology, and toxicity	16
Ethnobotanical study of Zhuang medicinal herbs of Ardisia: variety systematization, traditional uses, phytochemistry, pharmacology, clinical application, and toxicity	15
Andrographolide attenuates oxidative stress and apoptosis in osteoporosis rats via MEK/ERK and Beclin-1/ATG-5-mediated autophagy pathway	15
Sanshimao formula inhibits the hypoxia-induced pro-angiogenesis of hepatocellular carcinoma cells partly through regulating MKK6/p38 signaling pathway	15
Characterizing resistance in prostate cancer at a single cell level with hormonal treatment and epigenetic inhibitors	15
Chrysin prevents inflammation-coinciding liver steatosis via AMPK signalling	15
Natural product mitigation of ferroptosis in platinum-based chemotherapy toxicity: targeting the underpinning oxidative signaling pathways	14
The combination of astragaloside IV and Panax notoginseng saponins attenuates cerebral ischaemia–reperfusion injury in rats through ferroptosis and inflammation inhibition via activating Nrf2	14
Gegen Qinlian Decoction protects kidney in diabetic rats by improving intestinal barrier and regulating intestinal microbiota	14
Nutritional benefits, ethnomedicinal uses, phytochemistry, pharmacological properties and toxicity of Spondias mombin Linn: a comprehensive review	14
Corrigendum to: The role of lncRNA ANRIL in the progression of hepatocellular carcinoma	14
Euterpe oleracea Mart. (Açai) seed extract improves physical performance in old rats by restoring vascular function and oxidative status and activating mitochondrial muscle biogenesis	14
Effects of dietary supplementation with arboreal medicinal mushrooms on stress coping strategies, depressive and anxiety-like behavior of rats	14
Research progress of pharmacological effects of Siraitia grosvenorii extract	14
Targeting together cholinesterases and serotonin reuptake against Alzheimer’s disease	13
Corrigendum to: Remimazolam alleviates neuropathic pain via regulating bradykinin receptor B1 and autophagy	13
Three-dimensional printed dosage forms based on disease-focussed perspectives	13

Ginkgo biloba extracts (GBE) protect human RPE cells from t-BHP-induced oxidative stress and necrosis by activating the Nrf2-mediated antioxidant defence	13
Psidium guajava leaves extract alters colonic microbiome composition and reduces intestinal sodium absorption in rats exposed to a high-sodium diet	13
Modulation of PPAR-γ/Nrf2 and AGE/RAGE signaling contributes to the chrysin cardioprotection against myocardial damage following ischemia/reperfusion in diabetic rats	13
Eplerenone reduces renal ischaemia/reperfusion injury by modulating Klotho, NF-κB and SIRT1/SIRT3/PGC-1α signalling pathways	13
A comprehensive review of scientifically reported phytochemicals to manage allodynia in chronic diabetes complications	13
Azithromycin concentration in rabbits’ plasma and posterior segment of the eyes following oral drug administration: a dose-finding study for the application in ocular toxoplasmosis	13
Genus Lupinus (Fabaceae): a review of ethnobotanical, phytochemical and biological studies	13
Geraniol suppresses tumour growth and enhances chemosensitivity of 5-fluorouracil on breast carcinoma in mice: involvement of miR-21/PTEN signalling	13
Mechanistic insights of methylcinnamate in improving oxidative stress and inflammation in acetaminophen-induced hepatotoxic mice by upregulating Nrf2 pathway	13
Brusatol’s anticancer activity and its molecular mechanism: a research update	13
Role of the integrin-linked kinase/TGF-β/SMAD pathway in sitagliptin-mediated cardioprotective effects in a rat model of diabetic cardiomyopathy	13
Use of kersetin and fisetin flavonoids in combination with pregabalin and gabapentin in the treatment of neuropathic pain	13
Genipin improves obesity through promoting bile secretion and changing bile acids composition in diet-induced obese rats	13
Ginkgo biloba extracts protect human retinal Müller glial cells from t-BHP induced oxidative damage by activating the AMPK-Nrf2-NQO-1 axis	13
Potential interactions between triazole antifungal agents and lorlatinib based on ultra-performance liquid chromatography-tandem mass spectrometry in rat plasma	12
Dietary supplements and medicinal plants in urolithiasis: diet, prevention, and cure	12
Gap junction is essential for the antidepressant effects of fluoxetine	12
Research progress on the pharmacy of tetramethylpyrazine and its pharmacological activity in cardiovascular and cerebrovascular diseases	12
Different protective capability of chlorogenic acid and quercetin against indomethacin-induced gastrointestinal ulceration	12
Combination of metabolomics and network pharmacology analysis to decipher the mechanisms of total flavonoids of Litchi seed against prostate cancer	12
Schisandrin B ameliorates adjuvant-induced arthritis in rats via modulation of inflammatory mediators, oxidative stress, and HIF-1α/VEGF pathway	12
Dendrobium officinale Kimura et Migo: traditional uses, agricultural technology, processing, chemical composition, pharmacological mechanisms, toxicology, and applications	12
Development and in vitro evaluation of solution-based pressurized metered-dose inhaler formulations using green propellants	12
Development of benznidazole orally disintegrating tablets for paediatric patients	12
Patchouli alcohol against renal fibrosis of spontaneously hypertensive rats via Ras/Raf-1/ERK1/2 signalling pathway	11
Correction to: Curcumin solid dispersion-loaded in situ hydrogels for local treatment of injured vaginal bacterial infection and improvement of vaginal wound healing	11
Inhaled exogenous thymosin beta 4 suppresses bleomycin-induced pulmonary fibrosis in mice via TGF-β1 signalling pathway	11
Menthol-based self microemulsifying drug delivery system for augmented intestinal absorption of edoxaban	11
Effect of carvedilol on pharmacokinetics of sofosbuvir and its metabolite GS-331007: role of P-glycoprotein	11
Development and characterization of natural phenolics-rich extracts and formulations based on Putoria calabrica leaf for wound healing applications	11
Ginsenoside Rg3 inhibits renal cell carcinoma cell migration, invasion, colony formation, and tube formation and enhances apoptosis through promoting the DNA demethylation and histone acetylation	11
Ambroxol mitigates renal ischemia/reperfusion-induced cardiac and renal injury via Nrf2/HO-1 activation and TLR4 pathway inhibition	11
Shaoyao Gancao Decoction protects against dextran sulfate sodium-induced ulcerative colitis by down-regulating ferroptosis	11
Risk stratification of AUC upward deviation in patients with low serum creatinine levels treated with vancomycin: a multicenter retrospective study	10
Berberine suppresses the migration and invasion of colon cancer cells by inhibition of lipogenesis through modulation of promyelocytic leukemia zinc finger-mediated sterol-regulatory element binding p	10
Phoenixin 14 ameloriates pancreatic injury in streptozotocin-induced diabetic rats by alleviating oxidative burden	10
Propolis prevents vascular endothelial dysfunction by attenuating inflammation and oxidative damage in the chronic unpredictable stress model of depression in rats	10
Novel peptide calcitonin gene-related peptide antagonists for migraine therapy	10
Wedelolactone suppresses breast cancer growth and metastasis via regulating TGF-β1/Smad signaling pathway	10
Advances in inhaler therapy for asthma and chronic obstructive pulmonary disease: a comprehensive review of Fostair™ and Trimbow™	9
Effect of madecassoside in reducing oxidative stress and blood glucose in streptozotocin–nicotinamide-induced diabetes in rats	9
Alleviating vascular calcification with Bushen Huoxue formula in rats with chronic kidney disease by inhibiting the PTEN/PI3K/AKT signaling pathway through exosomal microRNA-32	9
3D DLP-printed cannabinoid microneedles patch and its pharmacokinetic evaluation in rats	9
Kaempferitrin, a major compound from ethanol extract of Chenopodium ambrosioides, exerts antitumour and hepatoprotective effects in the mice model of human liver cancer xenografts	9
Isolation, phytochemistry, characterization, biological activity, and application of Morinda officinalis How oligosaccharide: a review	9
The state and trends of cinnamaldehyde research over the past three decades: a bibliometric and visualized analysis	9
Monotropein alleviates sepsis-elicited acute lung injury via the NF-κB pathway	9
Potential of syringol and guaiacol in mitigating hyperglycemia associated dicarbonyl stress in rats subjected to high-fat high-fructose diet	9
Styrax (Liquidambar orientalis Mill.) promotes mitochondrial function and reduces cardiac damage following myocardial ischemic injury: the role of the AMPK-PGC1α signaling pathway	9
Research progress on ethnobotany, phytochemistry, pharmacological action, and applications of Engelhardia roxburghiana Wall: a review	9
Indolocarbazole alkaloid Loonamycin A inhibits triple-negative breast cancer cell stemness and Notch signalling	9
PD15, a steroidal saponin, induces apoptosis of HCT116 colorectal cancer cells via suppressing the Akt/GSK3β pathway	9
Pharmacological properties and derivatives of saikosaponins—a review of recent studies	9
Development and characterization of quetiapine-loaded microneedles-based transdermal patches for improved drug delivery	9
Homoplantaginin attenuates high glucose-induced vascular endothelial dysfunction via inhibiting store-operated calcium entry channel and endoplasmic reticulum stress	9
Botany, traditional uses, phytochemistry and pharmacological activity of Crataegus pinnatifida (Chinese hawthorn): a review	9
Imperatorin derivative OW1, a new vasoactive compound, attenuates cell proliferation and migration by inhibiting Nox1-mediated oxidative stress	9
Corrigendum to: An injectable liposome for sustained release of icariin to the treatment of acute blunt muscle injury	9
YiQi GuBen formula alleviates airway inflammation and airway remodeling in OVA-induced asthma mice through TLR4/NF-κB signaling pathway	8
Fisetin alleviates chronic urticaria by inhibiting mast cell activation via MRGPRX2	8
Circular RNA in autoimmune diseases: special emphasis on regulation mechanism in RA and SLE	8
Isoliquiritigenin: a potential drug candidate for the management of erectile dysfunction	8
Potential therapeutic role for pigment epithelium-derived factor in post-menopausal breast cancer bone metastasis	8
Retraction of: The antiproliferative and apoptotic effects of apigenin on glioblastoma cells	8
Shikonin mitigates cyclophosphamide-induced cardiotoxicity in mice: the role of sirtuin-1, NLRP3 inflammasome, autophagy, and apoptosis	8
Integration of pharmacodynamics and metabolomics to reveal rhubarb anthraquinone protection against nonalcoholic fatty liver disease rat model	8
Frondoside A of Cucumaria frondosa (Gennerus, 1767): Chemistry, biosynthesis, medicinal applications, and mechanism of actions	8
Ginsenoside Rb1 inhibits chronic stress-induced colorectal cancer via regulating glycolysis and β2-AR/CREB1 signaling pathway	8
Puerarin alleviates diabetic nephropathy by inhibiting Caspase-1-mediated pyroptosis	8
Shikonin in breast cancer treatment: a comprehensive review of molecular pathways and innovative strategies	8
Phytochemical profile and hepatoprotective potentiality of Phyllanthus genus: a review	8
Upregulation of HBXIP contributed to the anti-DND by ginsenoside Rg1 after global cerebral ischemia-reperfusion	8
Case study: cremophor EL-based liquid formulations as simple substitutes for amorphous solid dispersions in early preclinical in vivo studies	8
Phillyrin alleviates high glucose-induced oxidative stress and inflammation in HBZY-1 cells through inhibition of the PI3K/Akt signaling pathway	8
Chrysin and its nanoliposome ameliorated non-alcoholic steatohepatitis via inhibiting TLR4 signalling pathway	8
Glycation-induced age-related illnesses, antiglycation and drug delivery strategies	8
Circ_UTRN ameliorates caerulein-induced acute pancreatitis in vitro via reducing inflammation and promoting apoptosis through miR-320-3p/PTK2 axis	8
Ethyl 2,2-difluoro-2-(2-oxo-2H-chromen-3-yl) acetate attenuates the malignant biological behaviors of non-small cell lung cancer via suppressing EGFR/PI3K/AKT/mTOR signaling pathway	8
Anticancer potential of PEDF peptides	8
Explore the anti-inflammation mechanism of safflower total flavonoids in the treatment of endometritis based on celluar transcriptomics	8

The promising application of hydrogel microneedles in medical application	7
The dual inhibitor Sacubitril-valsartan ameliorate high-fat high-fructose-induced metabolic disorders in rats superiorly compared to valsartan only	7
Ligusticum chuanxiong Hort.: a review of its phytochemistry, pharmacology, and toxicology	7
Advances in ultrasound-mediated brain drug delivery	7
Melatonin alleviates high glucose-induced cardiomyocyte injury through suppressing mitochondrial FUNDC1-DRP1 axis	7
Genus Barleria L. (Acanthaceae): a review of its taxonomy, cytogenetics, phytochemistry and pharmacological potential	7
Hydroalcoholic extract of Araucaria sp. brown propolis alleviates ulcerative colitis induced by TNBS in rats by reducing inflammatory cell infiltration and oxidative damage	7
Statins and peripheral neuropathy in diabetic and non-diabetic cases: a systematic review	7
YLKTT, a potent biopeptide that ameliorates oxygen-glucose deprivation-induced neuronal cell ferroptosis by ACSL4/GPX4 and SLC7A11/GPX4 axis	7
Exploring the molecular mechanism of Taohong Siwu decoction in the treatment of non-small-cell lung cancer based on network pharmacology and molecular docking	7
Spotlight on Coenzyme Q10 in scopolamine-induced Alzheimer’s disease: oxidative stress/PI3K/AKT/GSK 3ß/CREB/BDNF/TrKB	7
Investigation of the effect of concurrently administered carvedilol, atorvastatin and bile salts on intestinal absorption of linagliptin	7
Targeting the CCL2–CCR2 signaling pathway: potential implications of statins beyond cardiovascular diseases	7
Revealing action mechanisms of Xiaoyaosan decoction for the treatment of nonalcoholic fatty liver in mice employing tandem mass tag quantitative proteomics	7
Pharmaceutical co-crystals: A green way to enhance drug stability and solubility for improved therapeutic efficacy	7
Ganoderma lucidum triterpenoids investigating their role in medicinal applications and genomic protection	7
Correction to: Circ_UTRN ameliorates caerulein-induced acute pancreatitis in vitro via reducing inflammation and promoting apoptosis through miR-320-3p/PTK2 axis	7
Mechanisms facilitating the uptake of carboxyl–polythene glycol-functionalized gold nanoparticles into multicellular spheroids	7
Hydroxyapatite-based nano-drug delivery system for nicotinamide mononucleotide (NMN): significantly enhancing NMN bioavailability and replenishing in vivo nicotinamide adenine dinucleotide (NAD	7
Effects of artemether on pancreatic islet morphology, islet cell turnover and α-cell transdifferentiation in insulin-deficient Glu CreERT2;ROSA26-eYFP diabetic m	7
Correction to: Patchouli alcohol against renal fibrosis of spontaneously hypertensive rats via Ras/Raf-1/ERK1/2 signalling pathway	7
Compare Phellodendri Chinensis Cortex before and after salt-water processing to ameliorate diabetic nephropathy via metabolomics and microbiome analysis	6
Mitochondrial transplantation attenuates toxicity in rat renal proximal tubular cells caused by Favipiravir	6
A comprehensive review of phytochemistry, pharmacology and quality control of plants from the genus Viola	6
Hyperoside, a natural flavonoid compound, attenuates Triptolide-induced testicular damage by activating the Keap1-Nrf2 and SIRT1-PGC1α signalling pathway	6
Pharmacokinetics of pazopanib: a review of the determinants, influencing factors and the clinical importance of therapeutic drug monitoring	6
An evaluation of the quality of Annona muricata leaf products	6
Co-administration of Ceratonia siliqua extract nanoparticles promotes the oral bioavailability and neurotherapeutic efficacy of donepezil in a dementia model	6
Protective effects of piperlongumine against adjuvant-induced arthritis in rats through modulating OPG/RANKL/NF-κB signaling pathway	6
Inula japonica ameliorated the inflammation and oxidative stress in LPS-induced acute lung injury through the MAPK/NF-κB and Keap1/Nrf2 signalling pathways	6
Tiaogan Jiejiu Tongluo formula alleviates hepatic steatosis in NAFLD mice by regulating AMPK signaling pathway	6
Protein phosphatase 2A inhibitors: a possible pharmacotherapy for benzodiazepine dependence	6
Engineering carrier nanoparticles with biomimetic moieties for improved intracellular targeted delivery of mRNA therapeutics and vaccines	6
A prediction method for the individual serum concentration and therapeutic effect for optimizing adalimumab therapy in inflammatory bowel disease	6
Phenylethanoid glycosides extract from Cistanche deserticola ameliorates atherosclerosis in apolipoprotein E-deficient mice and regulates intestinal PPARγ-LXRα-ABCA1 pathway	6
Intervention of non-alcoholic fatty liver disease by Ling Gui Zhu Gan Granules and its volatile components through the metabolism of intestinal microbiota and short-chain fatty acids	6
Research progress on chemical components and pharmacological action of Solanum lyratum Thunb	6
The Clock gene regulates kainic acid-induced seizures through inhibiting ferroptosis in mice	6
The mechanism of action of Botrychium (Thunb.) Sw. for prevention of idiopathic pulmonary fibrosis based on 1H-NMR-based metabolomics	6
Correction to: Modulation of NADPH oxidase and Nrf2/HO-1 pathway by vanillin in cisplatin-induced nephrotoxicity in rats	6
Unlocking molecular mechanisms of Saussurea costus (Falc.) Lipsch. root extract against experimentally induced hypothyroidism through integrated ultra-pe	6
Deciphering farnesol’s anti-arthritic and immunomodulatory potential by targeting multiple pathways: a combination of network pharmacology guided exploration and experimental verification	6
Chrysin ameliorates D-galactose-induced liver aging in mice: the impact of targeting Nrf2/AKT and CXCL1/TNF-α/P53 signaling pathways	6
Precision pharmaceutics: bioinformatics and pharmacogenomics as catalysts for personalized drug therapy	6
Integrated metabolomics and network pharmacology analysis to reveal the mechanisms of naringin against atherosclerosis	6
Population pharmacokinetic/pharmacodynamic evaluations of amikacin dosing in critically ill patients undergoing continuous venovenous hemodiafiltration	6
Coptisine protects against transient focal cerebral ischaemic injury by regulation of arachidonic acid metabolism	6
Clonidine ameliorates cisplatin-induced nephrotoxicity: impact on OCT2 and p38 MAPK pathway	5
Identification of the perpetrator imperatorin in Xin-yi-san-theophylline interaction: observed and predicted herb-drug interaction in rats	5
Metabolic reprogramming in head and neck cancer: therapeutic opportunities and challenges	5
Exploring the effects of a multicomponent phytoceutical health product in a Drosophila melanogaster ageing and repetitive concussion model	5
Activation of HSPA5 contributes to pazopanib-induced hepatotoxicity through l-ornithine metabolism pathway and endoplasmic reticulum stress	5
Piceatannol-3ʹ-O-β-d-glucopyranoside alleviates nephropathy via regulation of High mobility group B-1 (HMGB1)/Toll-like receptor 4 (TLR4)/Nuclear factor kappa B (NF-κB) signalling pathway	5
Antiovarian cancer mechanism of esculetin: inducing G0/G1 arrest and apoptosis via JAK2/STAT3 signalling pathway	5
Rosavin and salidroside attenuate microglia injury via nuclear factor κ -B signaling pathway	5
γ-Terpinene complexed with β-cyclodextrin attenuates spinal neuroactivity in animals with cancer pain by Ca2+ channel block	5
Anti-tumor effects of Thymus Caramanicus Jalas extract in mice through oxidative stress, inflammation and apoptosis	5
Biochemical changes to the inner ear contributing to diabetes-induced hearing loss: possible pharmacological targets for therapy	5
Ciprofol alleviates remifentanil-induced hyperalgesia by regulating α2GABAARs, NR2B, and P-CaMKIIα levels in the spinal cord and hippocampus	5
Neuropeptide W protects against ovarian oxidative injury and reinforces ovarian steroidogenic activity via the upregulation of ERα expression	5
Emerging avenues for the management of cerebral malaria	5
Isoliquiritigenin regulates microglial M1/M2 polarisation by mediating the P38/MAPK pathway in cerebral stroke	5
Trilobatin regulates glucose metabolism by ameliorating oxidative stress and insulin resistance in vivo and in vitro	5
Exploration of medicinal plants as potential therapeutics against COVID-19: molecular insights and drug development prospects with other significant medicinal information a retrospective exposition	5
Piperlongumine inhibits glioblastoma proliferation by inducing ferroptosis	5
Protective role of geraniol in high fat diet-induced NAFLD: balancing lipid homeostasis, antioxidant defence, and inflammatory responses	5
Targeting MAPK14 in microglial cells: neuroimmune implications of Panax ginseng in post-stroke inflammation	5
Oridonin inhibits Hela cell proliferation via downregulation of glutathione metabolism: a new insight from metabolomics	5
Investigating the nitric oxide pathway stimulated by rosuvastatin on the pathological effects of renal ischemia–reperfusion in rats	5
Brain uptake and distribution patterns of 2-hydroxypropyl-ß-cyclodextrin after intrathecal and intranasal administration	5
Exosome-like nanoparticles derived from Allium tuberosum prevent neuroinflammation in microglia-like cells	5
Si-Zhi Wan regulates osteoclast autophagy in osteoporosis through the AMPK signaling pathway to attenuate osteoclastogenesis	5
Puerarin improves Dioscorea bulbifera L.-induced liver injury by regulating drug transporters and the Nrf2/NF-κB/Bcl-2 signaling pathway	5
Exploration of anti-diabetic activity and metabolite profiling of Bruguiera cylindrica (l.) Bl.—in vivo anti-diabetic activity, exploration of molecular mechanism, and network pharmacolo	5
Homoharringtonine promotes non-small-cell lung cancer cell death via modulating HIF-1α/ERβ/E2F1 feedforward loop	5
Retraction to: Inhibiting the PI3K/Akt, NF-κB signalling pathways with syringic acid for attenuating the development of oral squamous cell carcinoma cells SCC131	5
Recent progress in three-dimensionally-printed dosage forms from a pharmacist perspective	5
Flavonoids as new regulators of mitochondrial potassium channels: contribution to cardioprotection	5
In vitro and in vivo performance of amorphous solid dispersions of ursolic acid as a function of polymer type and excipient addition	5
A network pharmacology-based approach to explore the active ingredients and molecular mechanism of Shen-Kui-Tong-Mai granules on a rat model with chronic heart failure	4
Ezetimibe alleviates acetic acid-induced ulcerative colitis in rats: targeting the Akt/NF-κB/STAT3/CXCL10 signaling axis	4
Peimisine ameliorates DSS-induced colitis by suppressing Jak–Stat activation and alleviating gut microbiota dysbiosis in mice	4
Inhalation of Curcumae Rhizoma volatile oil attenuates depression-like behaviours via activating the Nrf2 pathway to alleviate oxidative stress and improve mitochondrial dysfunction	4
Curcuma longa L. extract and residue prevent Alzheimer’s disease in mice by regulating microglia and TLR4/NF-κB signaling pathway	4
Paeonol protects against acute pancreatitis by Nrf2 and NF-κB pathways in mice	4
Mitracarpus frigidus reduces lipid metabolism and PGE2 levels in inflammatory cells	4
Juglans mandshurica Maximowicz as a traditional medicine: review of its phytochemistry and pharmacological activity in East Asia	4
Scutellarein: a review of chemistry and pharmacology	4
Correction to: Evaluating the protective effect of dapsone on experimental osteoarthritis models induced by MIA in male rats	4
Phytochemical analysis, anti-inflammatory property, wound-healing, and anti-granuloma effect of Moroccan aqueous leave extract of Moringa oleifera	4
Natural products derived from herbs as promising source for diarrhea predominant-irritable bowel syndrome via gut microbiota–serotonin pathway	4
Role of cyclooxygenase pathways in bowel fibrotic remodelling in a murine model of experimental colitis	4
Comparison of capecitabine concentrations determined by microsampling versus plasma concentrations for therapeutic drug monitoring: a pilot study	4
Doxorubicin-induced cardiotoxicity: causative factors and possible interventions	4
Limonin delays the progression of intervertebral disc degeneration in vivo and in vitro: the key role of the MAPK/NF-κB and necroptosis pathways	4