Journal of Pharmacy and Pharmacology

Papers
(The median citation count of Journal of Pharmacy and Pharmacology is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)
ArticleCitations
Improvement of primary Sjögren’s syndrome salivary gland function by Xinfeng capsule and its effect on EGR1-STAT3 signaling pathway59
Chrysin bonded to β-d-glucose tetraacetate enhances its protective effects against the neurotoxicity induced by aluminum in Swiss mice48
Comparative bioavailability of curcuminoids from a water-dispersible high curcuminoid turmeric extract against a generic turmeric extract: a randomized, cross-over, comparative, pharmacokinetic study39
A network pharmacology-based approach to explore the active ingredients and molecular mechanism of Shen-Kui-Tong-Mai granules on a rat model with chronic heart failure36
Patchouli alcohol against renal fibrosis of spontaneously hypertensive rats via Ras/Raf-1/ERK1/2 signalling pathway36
Study on the targeted regulation of Scutellaria baicalensis leaf on glutamine–glutamate metabolism and glutathione synthesis in the liver of d-gal ageing rats36
Pinus roxburghii alleviates bone porosity and loss in postmenopausal osteoporosis by regulating estrogen, calcium homeostasis and receptor activator of nuclear factor-κB, osteoprotegerin, cathe31
Design and optimization of 3D-bioprinted scaffold framework based on a new natural polymeric bioink31
Δ(9)-tetrahydrocannabinol protects cardiac tissue against endoplasmic reticulum and oxidative stresses, apoptosis, and inflammation in rats with hyperinsulinemia29
Peimisine ameliorates DSS-induced colitis by suppressing Jak–Stat activation and alleviating gut microbiota dysbiosis in mice28
Ganoderma lucidum ameliorates the diabetic nephropathy via down-regulatory effect on TGFβ-1 and TLR-4/NFκB signalling pathways25
Isoliquiritigenin attenuates inflammation and modulates Nrf2/caspase-3 signalling in STZ-induced aortic injury25
MTH-3 sensitizes oral cancer cells to cisplatin via regulating TFEB24
Docetaxel in combination with metformin enhances antitumour efficacy in metastatic breast carcinoma models: a promising cancer targeting based on PEGylated liposomes24
Corrigendum to: Distinct metabonomic signatures of Polygoni Multiflori Radix Praeparata against glucolipid metabolic disorders22
A comprehensive review of traditional uses, phytochemistry and pharmacology of Reynoutria genus22
Research progress on the pharmacy of tetramethylpyrazine and its pharmacological activity in cardiovascular and cerebrovascular diseases22
Synergistic anti-tumour activity of ginsenoside Rg3 and doxorubicin on proliferation, metastasis and angiogenesis in osteosarcoma by modulating mTOR/HIF-1α/VEGF and EMT signalling pathways22
3D Printing: an appealing technology for the manufacturing of solid oral dosage forms21
The potential of Ginkgo biloba in the treatment of human diseases and the relationship to Nrf2–mediated antioxidant protection21
A honokiol-enriched Magnolia officinalis Rehder & E.H. Wilson. bark extract possesses anxiolytic-like activity with neuroprotective effect through the modulation of CB1 receptor20
Gap junction is essential for the antidepressant effects of fluoxetine20
Ginsenoside Rg3 inhibits renal cell carcinoma cell migration, invasion, colony formation, and tube formation and enhances apoptosis through promoting the DNA demethylation and histone acetylation19
Isatis indigotica: a review of phytochemistry, pharmacological activities and clinical applications19
Vesicular drug delivery for the treatment of topical disorders: current and future perspectives18
Combination of metabolomics and network pharmacology analysis to decipher the mechanisms of total flavonoids of Litchi seed against prostate cancer18
Photoactivation of pheophorbide-a utilizing 670 nm LEDs elicits cancer suppressive effects in androgen-independent prostate cancer cellular models17
Near-infrared spectroscopy and HPLC combined with chemometrics for comprehensive evaluation of six organic acids in Ginkgo biloba leaf extract17
The inhibitory effect of trimetazidine on detrusor contractility – a potential repositioning of trimetazidine for the treatment of overactive bladder17
Targeting the CCL2–CCR2 signaling pathway: potential implications of statins beyond cardiovascular diseases16
β-Cyclodextrin-containing chitosan-oligonucleotide nanoparticles improve insulin bioactivity, gut cellular permeation and glucose consumption16
Icariside I reduces breast cancer proliferation, apoptosis, invasion, and metastasis probably through inhibiting IL-6/STAT3 signaling pathway16
Protective effects of duloxetine against chronic immobilisation stress-induced anxiety, depression, cognitive impairment and neurodegeneration in mice16
Medicinal plants from the Himalayan region for potential novel antimicrobial and anti-inflammatory skin treatments15
Phosphatidylinositol 3-kinase gamma participates in nimesulide-induced hepatic damage15
The application of natural compounds in uveal melanoma drug discovery15
Hepatoprotective effect of Spirulina platensis against carbon tetrachloride-induced liver injury in male rats15
Novel therapeutic approaches for Parkinson’s disease by targeting brain cholesterol homeostasis15
Pharmacokinetics-based chronoefficacy of Fuzi against chronic kidney disease15
3D-printed long-acting 5-fluorouracil implant to prevent conjunctival fibrosis in glaucoma15
Phillyrin improves myocardial remodeling in salt-sensitive hypertensive mice by reducing endothelin1 signaling15
Schisandrin B ameliorates adjuvant-induced arthritis in rats via modulation of inflammatory mediators, oxidative stress, and HIF-1α/VEGF pathway15
Dietary supplements and medicinal plants in urolithiasis: diet, prevention, and cure15
Lianhuaqingwen alleviates p53-mediated apoptosis in alveolar epithelial cells to prevent LPS-induced ALI14
In vitro and in vivo antihyperglycemic activity of the ethanol extract of Heritiera fomes bark and characterization of pharmacologically active phytomolecules14
Different protective capability of chlorogenic acid and quercetin against indomethacin-induced gastrointestinal ulceration14
Azithromycin concentration in rabbits’ plasma and posterior segment of the eyes following oral drug administration: a dose-finding study for the application in ocular toxoplasmosis14
Development of a comprehensive method based on quantitative 1H NMR for quality evaluation of Traditional Chinese Medicine injection: a case study of Danshen Injection14
Phytochemicals from medicinal plants from African forests with potentials in rheumatoid arthritis management14
Investigation of the effect of concurrently administered carvedilol, atorvastatin and bile salts on intestinal absorption of linagliptin14
Ginkgo biloba extracts (GBE) protect human RPE cells from t-BHP-induced oxidative stress and necrosis by activating the Nrf2-mediated antioxidant defence14
Genus Barleria L. (Acanthaceae): a review of its taxonomy, cytogenetics, phytochemistry and pharmacological potential13
Nrf2 signalling pathway and autophagy impact on the preventive effect of green tea extract against alcohol-induced liver injury13
Assessment of efficacy of chrysin in diabetes-associated cardiac complications in chick embryo and murine model13
Anti-inflammatory, anti-oxidant and anti-apoptotic effects of olive leaf extract in cardiac tissue of diabetic rats13
Effects of artemether on pancreatic islet morphology, islet cell turnover and α-cell transdifferentiation in insulin-deficient Glu CreERT2;ROSA26-eYFP diabetic m13
Dihydroisotanshinone I regulates ferroptosis via PI3K/AKT pathway to enhance cisplatin sensitivity in lung adenocarcinoma13
Jie Geng Tang reverses cisplatin resistance through the Nrf2 pathway in lung cancer13
Inhibition of human ether-à-go-go-related gene K+ currents expressed in HEK293 cells by three gingerol components from ginger13
Scutellarein: a review of chemistry and pharmacology13
Antiviral activity against Zika virus of a new formulation of curcumin in poly lactic-co-glycolic acid nanoparticles13
An in vitro evaluation of antitumor activity of sirolimus-encapsulated liposomes in breast cancer cells13
Mechanisms facilitating the uptake of carboxyl–polythene glycol-functionalized gold nanoparticles into multicellular spheroids12
Hydroxyapatite-based nano-drug delivery system for nicotinamide mononucleotide (NMN): significantly enhancing NMN bioavailability and replenishing in vivo nicotinamide adenine dinucleotide (NAD12
Indobufen alleviates ischemic stroke injury by regulating transcription factor NRF2 and inhibiting ATG5 expression12
Genipin improves obesity through promoting bile secretion and changing bile acids composition in diet-induced obese rats12
Disulfiram attenuates lipopolysaccharide-induced acute kidney injury by suppressing oxidative stress and NLRP3 inflammasome activation in mice12
A review on the ethnopharmacology, phytochemistry and pharmacology of Polygonum hydropiper Linn.12
Potential interactions between triazole antifungal agents and lorlatinib based on ultra-performance liquid chromatography-tandem mass spectrometry in rat plasma12
Attenuation of opioid tolerance by ETA receptor antagonist, BQ123, administered intravenously in mice12
Research progress regarding potential effects of traditional Chinese medicine on postoperative intestinal obstruction12
Protopanaxadiol prevents cisplatin-induced acute kidney injury by regulating ferroptosis12
Enhancement of antiproliferative potential of metformin against melanoma mice B16 cells using an optimized liposomal drug delivery system12
Epidermal growth factor receptor as a potential target of momordin Ic to promote apoptosis of cholangiocarcinoma cells12
3-Demethyl-2-geranyl-4-prenylbellidifoline, a natural xanthone with diuretic and kidney protective properties12
The role of lncRNA ANRIL in the progression of hepatocellular carcinoma12
GL-V9 synergizes with oxaliplatin of colorectal cancer via Wee1 degradation mediated by HSP90 inhibition12
Inhalation of Curcumae Rhizoma volatile oil attenuates depression-like behaviours via activating the Nrf2 pathway to alleviate oxidative stress and improve mitochondrial dysfunction11
β-Caryophyllene attenuates lipopolysaccharide-induced acute lung injury via inhibition of the MAPK signalling pathway11
Spotlight on Coenzyme Q10 in scopolamine-induced Alzheimer’s disease: oxidative stress/PI3K/AKT/GSK 3ß/CREB/BDNF/TrKB11
The hepatoprotective effect of silibinin after hepatic ischemia/reperfusion in a rat model is confirmed by immunohistochemistry and qRT-PCR11
Melatonin alleviates high glucose-induced cardiomyocyte injury through suppressing mitochondrial FUNDC1-DRP1 axis11
Tilianin obtained from Agastache mexicana inhibits monoamine oxidase and modifies depressive behavior in rats11
Effects of borneol combined with astragaloside IV and Panax notoginseng saponins regulation of microglia polarization to promote neurogenesis after cerebral ischaemia11
Atractylodin inhibited the migration and induced autophagy in cholangiocarcinoma cells via PI3K/AKT/mTOR and p38MAPK signalling pathways11
Narrow Therapeutic Index drugs: clinical pharmacology perspective11
Network pharmacology prediction, molecular docking, and molecular dynamics simulation-based strategy to explore the potential mechanism of Huashanshen dripping pill against asthma11
Study of the cardioprotective effects of crocin on Human Cardiac Myocyte cells and reduction of oxidative stress produced by aluminum phosphide poisoning11
Doxorubicin-induced cardiotoxicity: causative factors and possible interventions11
The natural polyphenol fisetin in atherosclerosis prevention: a mechanistic review10
Serum autotaxin level: a promising diagnostic biomarker in differentiating Graves’ disease and thyroiditis10
PI3K/AKT/Nrf2 signalling pathway is involved in the ameliorative effects of xanthohumol on amyloid β-induced oxidative damage and bone loss10
Decoding the power of saponins in ferroptosis regulation and disease intervention: a review10
GC-MS- and LC-TOF-MS/MS-based ginger volatile oil serum analysis and the potential mechanism of the anticancer effect of serum component citral on MCF-7 breast cancer cells10
Anti-liver cancer therapeutic targets and safety of usenamine A in experimental liver cancer10
Pharmacological investigation of genistein for its therapeutic potential against nitroglycerin-induced migraine headache10
Hyperoside, a natural flavonoid compound, attenuates Triptolide-induced testicular damage by activating the Keap1-Nrf2 and SIRT1-PGC1α signalling pathway10
Homoharringtonine sensitizes pancreatic cancer to erlotinib by direct targeting and miRNA-130b-3p-mediated EphB4-JAK2-STAT3 axis10
Solanine induces ferroptosis in colorectal cancer cells through ALOX12B/ADCY4 molecular axis10
Deciphering farnesol’s anti-arthritic and immunomodulatory potential by targeting multiple pathways: a combination of network pharmacology guided exploration and experimental verification10
Potential therapeutic efficacy of pachymic acid in chronic kidney disease induced in rats: role of Wnt/β-catenin/renin–angiotensin axis10
A synthetic resveratrol–curcumin hybrid derivative exhibits chemopreventive effects on colon pre-neoplastic lesions by targeting Wnt/β-catenin signaling, anti-inflammatory and antioxidant pathways10
The beneficial impact of curcumin on cardiac lipotoxicity9
Exploration of the potential mechanism of aqueous extract of Artemisia capillaris for the treatment of non-alcoholic fatty liver disease based on network pharmacology and experimental verificat9
Lupeol induces autophagy and apoptosis with reduced cancer stem-like properties in retinoblastoma via phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin inhibition9
Hypericin-mediated photodynamic therapy for the treatment of cancer: a review9
Paeonol protects against acute pancreatitis by Nrf2 and NF-κB pathways in mice9
Repurposing of sildenafil as antitumour; induction of cyclic guanosine monophosphate/protein kinase G pathway, caspase-dependent apoptosis and pivotal reduction of Nuclear factor kappa light chain enh9
Correction to: Current treatments for oropharyngeal squamous cell carcinoma and the move towards molecular therapy9
The therapeutic potential of curculigoside in poststroke depression: a focus on hippocampal neurogenesis and mitochondrial function9
New insight into the molecular mechanism of TCM Bufei Huoxue formula for chronic obstructive pulmonary disease based on network pharmacology and experimental verification9
PAMAM dendrimers as mediators of dermal and transdermal drug delivery: a review9
Renoprotective effect of liraglutide on diabetic nephropathy by modulation of Krüppel-like transcription factor 5 expression in rats9
Phoenixin 14 ameloriates pancreatic injury in streptozotocin-induced diabetic rats by alleviating oxidative burden9
Mechanisms exploration of Xiaojin Pills on lung cancer based on metabolomics and network pharmacology9
Hydroalcoholic extract of Araucaria sp. brown propolis alleviates ulcerative colitis induced by TNBS in rats by reducing inflammatory cell infiltration and oxidative damage9
A prediction method for the individual serum concentration and therapeutic effect for optimizing adalimumab therapy in inflammatory bowel disease9
Schisandrin B restores M1/M2 balance through miR-124 in lipopolysaccharide-induced BV2 cells9
Production of mRNA lipid nanoparticles using advanced crossflow micromixing9
Dose individualization of intravenous busulfan in pediatric patients undergoing bone marrow transplantation: impact and in vitro evaluation of infusion lag-time9
Preparation and evaluation of reduction-responsive micelles based on disulfide-linked chondroitin sulfate A-tocopherol succinate for controlled antitumour drug release9
Insulinotropic and antidiabetic properties of Eucalyptus citriodora leaves and isolation of bioactive phytomolecules9
Advantages of introducing an effective crystalline inhibitor in curcumin amorphous solid dispersions formulated by Eudragit E1008
Correction to: Evaluating the protective effect of dapsone on experimental osteoarthritis models induced by MIA in male rats8
Identification of human uridine diphosphate-glucuronosyltransferase isoforms responsible for the glucuronidation of 10,11-dihydro-10-hydroxy-carbazepine8
Physcion-8-O-β-d-glucoside interferes with the nuclear factor-κB pathway and downregulates P-glycoprotein expression to reduce paclitaxel resistance in ovarian cancer cells8
Chronotoxicity of Semen Strychni is associated with circadian metabolism and transport in mice8
Phenylethanoid glycosides extract from Cistanche deserticola ameliorates atherosclerosis in apolipoprotein E-deficient mice and regulates intestinal PPARγ-LXRα-ABCA1 pathway8
Angiotensin II upregulates endothelin receptors through the adenosine monophosphate-activated protein kinase/sirtuin 1 pathway in vascular smooth muscle cells8
Eupafolin induces autophagy and apoptosis in B-cell non-Hodgkin lymphomas8
Targeting of MNK/eIF4E overcomes chemoresistance in cervical cancer8
Treatment of liver cancer cells with ethyl acetate extract of Crithmum maritimum permits reducing sorafenib dose and toxicity maintaining its efficacy8
Thyme extract could overcome diabetes-induced reproductive dysfunction by inhibiting oxidative damage and increasing the expression of insulin receptor substrate and pyruvate kinase in the rat sperm8
Augmented cytotoxicity using the physical adsorption of Poloxamer 188 on allicin-loaded gelatin nanoparticles8
Alamandine protects against renal ischaemia–reperfusion injury in rats via inhibiting oxidative stress8
Ling-Gui-Zhu-Gan decoction protects against doxorubicin-induced myocardial injury by downregulating ferroptosis8
Phloretin: a comprehensive review of its potential against diabetes and associated complications8
Deciphering the mechanism of Chaihu Shugan San in the treatment of nonalcoholic steatohepatitis using network pharmacology and molecular docking8
Engineering carrier nanoparticles with biomimetic moieties for improved intracellular targeted delivery of mRNA therapeutics and vaccines8
Antimicrobial and anthelmintic activities of the ethanolic extract, fractions and isolated compounds from Manilkara zapota L. P. Royen (Sapotaceae)8
An integrated strategy to explore the wine-processed mechanism of Corni Fructus on chronic renal failure based on metabolomics, network analysis and bioinformatics approaches8
Jujuboside A ameliorates cognitive deficiency in delirium through promoting hippocampal E4BP4 in mice8
Modulation of NF-κB and MAPK signalling pathways by hydrolysable tannin fraction from Terminalia chebula fruits contributes to its anti-inflammatory action in RAW 264.7 cells7
Correction to: Patchouli alcohol against renal fibrosis of spontaneously hypertensive rats via Ras/Raf-1/ERK1/2 signalling pathway7
A comprehensive review of phytochemistry, pharmacology and quality control of plants from the genus Viola7
Ezetimibe alleviates acetic acid-induced ulcerative colitis in rats: targeting the Akt/NF-κB/STAT3/CXCL10 signaling axis7
Oligo/polysaccharides from Cyathula officinalis and Achyranthes bidentata: a review of structures and bioactivities7
Roles of pigment epithelium-derived factor in cardiomyocytes: implications for use as a cardioprotective therapeutic7
N-palmitoylethanolamide synergizes the antinociception of morphine and gabapentin in the formalin test in mice7
Mitracarpus frigidus reduces lipid metabolism and PGE2 levels in inflammatory cells7
In silico evidence of bitopertin’s broad interactions within the SLC6 transporter family7
Pharmacological intervention in oxidative stress as a therapeutic target in neurological disorders7
Effect of carrier material on the thermodynamic properties and recrystallization kinetics of andrographolide-solid dispersion7
Shaoyao Gancao Decoction protects against dextran sulfate sodium-induced ulcerative colitis by down-regulating ferroptosis7
Juglans mandshurica Maximowicz as a traditional medicine: review of its phytochemistry and pharmacological activity in East Asia7
Comparison of capecitabine concentrations determined by microsampling versus plasma concentrations for therapeutic drug monitoring: a pilot study7
Anti-inflammatory effect of Adelia ricinella L. aerial parts7
Exploring the clinical relevance of “Angico Gum”: an effective biopolymer for topical protection of oesophageal mucosa in gastroesophageal reflux disease patients7
Wei-Tong-Xin exerts anti-inflammatory effects through TLR4-mediated macrophages M1/M2 polarization and affects GLP-1 secretion7
Novel peptide calcitonin gene-related peptide antagonists for migraine therapy7
The pleiotropic effects of statins in rheumatoid arthritis7
Pharmacological properties and derivatives of saikosaponins—a review of recent studies6
Erythrocyte membrane-camouflaged mesoporous silica composite nanoparticles for loading and controlled release of the hepatoprotective agent silibinin: A-synthesis and physicochemical characterization6
Improvement of the bioavailability of curcumin by a supersaturatable self nanoemulsifying drug delivery system with incorporation of a hydrophilic polymer: in vitro and in vivo character6
Effect of carvedilol on pharmacokinetics of sofosbuvir and its metabolite GS-331007: role of P-glycoprotein6
Oxymatrine screened from Sophora flavescens by cell membrane immobilized chromatography relieves histamine-independent itch6
Eleutheroside E functions as anti-cervical cancer drug by inhibiting the phosphatidylinositol 3-kinase pathway and reprogramming the metabolic responses6
In-line monitoring and endpoint determination of percolation process of herbal medicine using ultraviolet spectroscopy combined with convolutional neural network6
Protective effect of Allium scorodoprasum L. ethanolic extract in cyclophosphamide-induced hepatotoxicity model in rats6
A review on phytochemical and therapeutic potential of Iris germanica6
Evaluation of the effects of nanoparticles on the therapeutic function of platelet: a review6
Tubastatin A suppresses the proliferation of fibroblasts in epidural fibrosis through phosphatidylinositol-3-kinase/protein kinase B/mammalian target of rapamycin (PI3K/AKT/mTOR) signalling pathway6
Remifentanil protects heart from myocardial ischaemia/reperfusion (I/R) injury via miR-206-3p/TLR4/NF-κB signalling axis6
Doxorubicin alters the disposition of phenytoin by reducing its metabolic elimination and binding affinity to serum albumin in rats6
Chalcone-rich extracts from Lonchocarpus cultratus roots present in vitro leishmanicidal and immunomodulatory activity6
Dopamine signalling in pancreatic islet cells and role in adaptations to metabolic stress6
Environmental toxicants, oxidative stress and health adversities: interventions of phytochemicals6
Glucosamine attenuates drug resistance in Mitoxantrone-resistance breast cancer cells6
Rosmarinic acid ameliorates septic-associated mortality and lung injury in mice via GRP78/IRE1α/JNK pathway6
Wedelolactone suppresses breast cancer growth and metastasis via regulating TGF-β1/Smad signaling pathway6
Protective effects of Radix Isatidis polysaccharide ameliorates obesity via promotion AMPK pathway in high-fat-diet-induced obese rats and 3T3-L1 adipocyte cells6
Limonin delays the progression of intervertebral disc degeneration in vivo and in vitro: the key role of the MAPK/NF-κB and necroptosis pathways6
Berberine suppresses the migration and invasion of colon cancer cells by inhibition of lipogenesis through modulation of promyelocytic leukemia zinc finger-mediated sterol-regulatory element binding p6
Antimalarial primaquine for spinal sensory and motor blockade in rats6
Rhamnetin: a review of its pharmacology and toxicity6
Study of the inclusion complexes formed between 4-phenylbutyrate and α-, β- and γ-cyclodextrin in solution and evaluation on their taste-masking properties6
A simple and effective method for the preparation of high-purity shikimic acid from chromatography wash effluent of Ginkgo biloba leaf extract by macroporous resin considering the effect of var6
Fused deposition modelling 3D printing proof-of-concept study for personalised inner ear therapy6
Ephedra sinica polysaccharide alleviates airway inflammations of mouse asthma-like induced by PM2.5 and ovalbumin via the regulation of gut microbiota and short chain fatty acid6
Drug resistance via radixin-mediated increase of P-glycoprotein membrane expression during SNAI1-induced epithelial-mesenchymal transition in HepG2 cells6
Prediction of the potential mechanism of compound gingerol against liver cancer based on network pharmacology and experimental verification6
Propolis prevents vascular endothelial dysfunction by attenuating inflammation and oxidative damage in the chronic unpredictable stress model of depression in rats6
Oral biopharmaceutics tools: recent progress from partnership through the Pharmaceutical Education and Research with Regulatory Links collaboration6
Raspberry ketone improves non-alcoholic fatty liver disease induced in rats by modulating sphingosine kinase/sphingosine-1-phosphate and toll-like receptor 4 pathways6
Fructus arctii: an overview on its traditional uses, pharmacology and phytochemistry6
Legumain: a potential biomarker for atherosclerosis6
Astaxanthin protects against pirarubicin-induced H9c2 cardiomyocytes by adjusting microRNA-494-3p-mediated MDM4/p53 signalling pathway6
Short overview on the relevance of microRNA–reactive oxygen species (ROS) interactions and lipid peroxidation for modulation of oxidative stress-mediated signalling pathways in cancer treatment5
Rhein induces apoptosis of AGS and MGC803 cells by regulating the Ras/PI3K/AKT and p38/MAPK signaling pathway5
p-Coumaric acid mitigates lipopolysaccharide induced brain damage via alleviating oxidative stress, inflammation and apoptosis5
Effect of total glucosides of paeony and Tripterygium wilfordii polyglycosides on erythrocyte methotrexate polyglutamates in rats, analysed using ultra-high-performance liquid chromatography-ta5
Cilostazol attenuated prenatal valproic acid-induced behavioural and biochemical deficits in a rat model of autism spectrum disorder5
Role of cyclooxygenase pathways in bowel fibrotic remodelling in a murine model of experimental colitis5
Mechanism of Guishao Yigong decoction in treating colorectal cancer based on network pharmacology and experimental validation5
Naringenin ameliorates vascular senescence and atherosclerosis involving SIRT1 activation5
Remimazolam alleviates neuropathic pain via regulating bradykinin receptor B1 and autophagy5
Therapeutically important bioactive compounds of the genus Polygonum L. and their possible interventions in clinical medicine5
Ganoderma lucidum polysaccharides protect against sepsis-induced cardiac dysfunction by activating SIRT15
The potential protective effect of the Polygonum hydropiper L against the development of fructose-induced oxidative stress and metabolic disorders in male Sprague-Dawely rats5
Ginsenoside Rb1 ameliorates hippocampal neuroinflammation in rats after intracerebral hemorrhage by inactivating the TLR4/NF-kB pathway5
Preparation, characteristic, biological activities, and application of polysaccharide from Lilii Bulbus: a review5
Correction to: Curcumin solid dispersion-loaded in situ hydrogels for local treatment of injured vaginal bacterial infection and improvement of vaginal wound healing5
Aprepitant: an antiemetic drug, contributes to the prevention of acute lung injury with its anti-inflammatory and antioxidant properties5
The mechanism of action of Botrychium (Thunb.) Sw. for prevention of idiopathic pulmonary fibrosis based on 1H-NMR-based metabolomics5
Function and inhibition of Haspin kinase: targeting multiple cancer therapies by antimitosis5
Homoplantaginin attenuates high glucose-induced vascular endothelial dysfunction via inhibiting store-operated calcium entry channel and endoplasmic reticulum stress5
Advances in inhaler therapy for asthma and chronic obstructive pulmonary disease: a comprehensive review of Fostair™ and Trimbow™5
Modulation of multiple cellular signalling pathways as targets for anti-inflammatory and anti-tumorigenesis action of Scopoletin5
The role of microRNAs on doxorubicin drug resistance in breast cancer5
Inhaled exogenous thymosin beta 4 suppresses bleomycin-induced pulmonary fibrosis in mice via TGF-β1 signalling pathway5
Natural products derived from herbs as promising source for diarrhea predominant-irritable bowel syndrome via gut microbiota–serotonin pathway5
Polysaccharides of Grifola frondosa ameliorate oxidative stress and hypercholesterolaemia in hamsters fed a high-fat, high-cholesterol diet5
Fat mass and obesity-associated protein inhibit the pathology of rheumatoid arthritis through the NSUN2/SFRP1/Wnt/β-catenin signal axis5
1,8-cineole ameliorates ischaemic brain damage via TRPC6/CREB pathways in rats5
Cannabidiol prevents chemotherapy-induced neuropathic pain by modulating spinal TLR4 via endocannabinoid system activation5
Pharmacokinetics of nano- and microcrystal formulations of low solubility compounds after intramuscular injection to mice5
Ameliorative effects of garlic oil on FNDC5 and irisin sensitivity in liver of streptozotocin-induced diabetic rats4
The methanol extract of red algae, Dichotomaria obtusata, from Persian Gulf promotes in vitro osteogenic differentiation of bone marrow mesenchymal stem cells; a biological and phytochem4
Population pharmacokinetic/pharmacodynamic evaluations of amikacin dosing in critically ill patients undergoing continuous venovenous hemodiafiltration4
The effect of patient’s body weight, infusion connection point, and infusion pump position on intravenous multi-infusion drug delivery at low infusion rates suitable for premature neonates4
Exploring various measures of the area under the curve for the assessment of dose-proportionality and estimation of bioavailability4
NUPR1 participates in YAP-mediate gastric cancer malignancy and drug resistance via AKT and p21 activation4
Novel resveratrol smart lipids; design, formulation, and biological evaluation of anticancer activity4
Performance and paroxetine stability in tablets manufactured by fused deposition modelling-based 3D printing4
N(Omega)-nitro-l-arginine methyl ester potentiates lidocaine analgesic and anaesthetic effect in rats4
Systemic administration of sunflower oil exerts neuroprotection in a mouse model of transient focal cerebral ischaemia4
Moringa oleifera: a systematic review of its botany, traditional uses, phytochemistry, pharmacology and toxicity4
Monotropein alleviates sepsis-elicited acute lung injury via the NF-κB pathway4
Dioscorea zingiberensis ameliorates diabetic nephropathy by inhibiting NLRP3 inflammasome and curbing the expression of p66Shc in high-fat diet/streptozotocin-induced diabetic mice4
Grape seed extract improved the fertility-enhancing effect of atorvastatin in high-fat diet-induced testicular injury in rats: involvement of antioxidant and anti-apoptotic effects4
Albiflorin alleviation efficacy in osteoarthritis injury using in-vivo and in-vitro models4
Phytochemical study and immunomodulatory activity of Fraxinus excelsior L.4
Analysis of the clinical characteristics of the liver injury induced by levetiracetam4
Toxicological and chemoprevention studies of Dalbergia ecastaphyllum (L.) Taub. stem, the botanical source of Brazilian red propolis4
Role of heme oxygenase-1 in the antidepressant-like effect of ursolic acid in the tail suspension test4
Styrax (Liquidambar orientalis Mill.) promotes mitochondrial function and reduces cardiac damage following myocardial ischemic injury: the role of the AMPK-PGC1α signaling pathway4
Examination of Hibiscus sabdariffa’s bioactive arsenal: pharmacological prospects and comprehensive insights into catalysing health and wellness through its therapeutic attributes—an exposition4
Evaluation of in vivo and ex vivo pre-treated bone marrow-derived mesenchymal stem cells with resveratrol in streptozotocin-induced type 1 diabetic rats4
Cinobufagin: a promising therapeutic agent for cancer4
Inula japonica ameliorated the inflammation and oxidative stress in LPS-induced acute lung injury through the MAPK/NF-κB and Keap1/Nrf2 signalling pathways4
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