OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Pharmacology and Experimental Therapeutics is 25. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
The Pharmacological Case for Cannabigerol	89
Drug Discovery Strategies for SARS-CoV-2	82
Comparative Pharmacokinetics of Δ⁹-Tetrahydrocannabinol in Adolescent and Adult Male Mice	55
RNAi-Based Therapeutics and Novel RNA Bioengineering Technologies	50
Pharmacological Comparison of Mitragynine and 7-Hydroxymitragynine: In Vitro Affinity and Efficacy forμ-Opioid Receptor and Opioid-Like Behavioral Effects in Rats	50
MK-8719, a Novel and Selective O-GlcNAcase Inhibitor That Reduces the Formation of Pathological Tau and Ameliorates Neurodegeneration in a Mouse Model of Tauopathy	45
Empagliflozin Improves the MicroRNA Signature of Endothelial Dysfunction in Patients with Heart Failure with Preserved Ejection Fraction and Diabetes	39
Discovery of M5049: A Novel Selective Toll-Like Receptor 7/8 Inhibitor for Treatment of Autoimmunity	38
Strategies for DevelopingκOpioid Receptor Agonists for the Treatment of Pain with Fewer Side Effects	37
Nonclinical Characterization of the Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor Roxadustat, a Novel Treatment of Anemia of Chronic Kidney Disease	37
Apigenin Ameliorates Insulin Resistance and Lipid Accumulation by Endoplasmic Reticulum Stress and SREBP-1c/SREBP-2 Pathway in Palmitate-Induced HepG2 Cells and High-Fat Diet–Fed Mice	33
Analgesia with Gabapentin and Pregabalin May Involve N-Methyl-d-Aspartate Receptors, Neurexins, and Thrombospondins	32
Acetate, a Short-Chain Fatty Acid, Acutely Lowers Heart Rate and Cardiac Contractility Along with Blood Pressure	32
Monoclonal Antibodies Counteract Opioid-Induced Behavioral and Toxic Effects in Mice and Rats	32
Dual-Modified Liposome for Targeted and Enhanced Gene Delivery into Mice Brain	31
Fentanyl but not Morphine Interacts with Nonopioid Recombinant Human Neurotransmitter Receptors and Transporters	31
ELX-02 Generates Protein via Premature Stop Codon Read-Through without Inducing Native Stop Codon Read-Through Proteins	30
Chronic Morphine-Induced Changes in Signaling at the A₃Adenosine Receptor Contribute to Morphine-Induced Hyperalgesia, Tolerance, and Withdrawal	28
AM833 Is a Novel Agonist of Calcitonin Family G Protein–Coupled Receptors: Pharmacological Comparison with Six Selective and Nonselective Agonists	27
Pharmacologic Characterization of ALD403, a Potent Neutralizing Humanized Monoclonal Antibody Against the Calcitonin Gene-Related Peptide	27
Parsaclisib Is a Next-Generation Phosphoinositide 3-Kinase δ Inhibitor with Reduced Hepatotoxicity and Potent Antitumor and Immunomodulatory Activities in Models of B-Cell Malignancy	26
p38α Regulates Expression of DUX4 in a Model of Facioscapulohumeral Muscular Dystrophy	25
Different Antioxidative and Antiapoptotic Effects of Piceatannol and Resveratrol	25
Microglia and Other Myeloid Cells in Central Nervous System Health and Disease	25
Shaping Microglial Phenotypes Through Estrogen Receptors: Relevance to Sex-Specific Neuroinflammatory Responses to Brain Injury and Disease	25

The Role of Smoking and Nicotine in the Transmission and Pathogenesis of COVID-19