Journal of Periodontology

Article	Citations
Economic burden of periodontitis in the United States and Europe: An updated estimation	92
Periodontitis activates the NLRP3 inflammasome in serum and saliva	91
A re‐evaluation of scaling and root planing	71
Independent impact of periodontitis and cardiovascular disease on elevated soluble urokinase‐type plasminogen activator receptor (suPAR) levels	66
A case‐control study on the association between periodontitis and coronavirus disease (COVID‐19)	65
Global, regional, and national burden of periodontitis from 1990 to 2019: Results from the Global Burden of Disease study 2019	56
Dysbiosis revisited: Understanding the role of the oral microbiome in the pathogenesis of gingivitis and periodontitis: A critical assessment	51
Inflammation of the periodontium associates with risk of future cardiovascular events	46
Senescent cells exacerbate chronic inflammation and contribute to periodontal disease progression in old mice	39
Does the subepithelial connective tissue graft in conjunction with a coronally advanced flap remain as the gold standard therapy for the treatment of single gingival recession defects? A systematic re	36
Apoptotic extracellular vesicles alleviate Pg‐LPS induced inflammatory responses of macrophages via AMPK/SIRT1/NF‐κB pathway and inhibit osteoclast formation	33
Performance of the 2017 AAP/EFP case definition compared with the CDC/AAP definition in population‐based studies	32
Prevalence and risk indicators of midfacial peri‐implant soft tissue dehiscence at single site in the esthetic zone: A cross‐sectional clinical and ultrasonographic study	32
Role of thin gingival phenotype and inadequate keratinized mucosa width (<2 mm) as risk indicators for peri‐implantitis and peri‐implant mucositis	31
Porphyromonas gingivalis outer membrane vesicles inhibit the invasion of Fusobacterium nucleatum into oral epithelial cells by downregulating FadA and FomA	30
Specific inhibition of IL‐6 receptor attenuates inflammatory bone loss in experimental periodontitis	28
Fibromyalgia and periodontitis: Bidirectional associations in population‐based 15‐year retrospective cohorts	28
microRNA‐146a and ‐155, upregulated by periodontitis and type 2 diabetes in oral fluids, are predicted to regulate SARS‐CoV‐2 oral receptor genes	27
Microbial dysbiosis: The root cause of periodontal disease	27
Is bleeding on probing a reliable clinical indicator of peri‐implant diseases?	27
Efficacy of biologics for the treatment of periodontal infrabony defects: An American Academy of Periodontology best evidence systematic review and network meta‐analysis	26
Repeated delivery of chlorhexidine chips for the treatment of peri‐implantitis: A multicenter, randomized, comparative clinical trial	26
American Academy of Periodontology best evidence consensus statement on the use of biologics in clinical practice	25
Nitrate‐rich diet alters the composition of the oral microbiota in periodontal recall patients	25
Impact of N‐terminal pro‐B‐type natriuretic peptide and related inflammatory biomarkers on periodontal treatment outcomes in patients with periodontitis: An explorative human randomized‐controlled cli	24

Poor oral health status and adverse COVID‐19 outcomes: A preliminary study in hospitalized patients	22
Immediate single‐tooth implant placement with simultaneous bone augmentation versus delayed implant placement after alveolar ridge preservation in bony defect sites in the esthetic region: A 5‐year ra	22
Tonsillectomy as a risk factor of periodontitis: A population‐based cohort study	22
Periodontal regenerative therapy in patients with type 2 diabetes using minimally invasive surgical technique with enamel matrix derivative under 3‐year observation: A prospective cohort study	22
Adherence to Mediterranean diet, physical activity level, and severity of periodontitis: Results from a university‐based cross‐sectional study	21
Resolution of peri‐implantitis by means of implantoplasty as adjunct to surgical therapy: A retrospective study	20
Periodontitis and cognitive impairment in older adults: The mediating role of mitochondrial dysfunction	20
Salivary and serum oxidative stress biomarkers and advanced glycation end products in periodontitis patients with or without diabetes: A cross‐sectional study	20
Effect of adjunctive systemic antibiotics on microbial populations compared with scaling and root planing alone for the treatment of periodontitis: A pilot randomized clinical trial	19
Efficacy of biologics for alveolar ridge preservation/reconstruction and implant site development: An American Academy of Periodontology best evidence systematic review	19
The role of PHF8 and TLR4 in osteogenic differentiation of periodontal ligament cells in inflammatory environment	19
Efficacy of inorganic bovine bone combined with leukocyte and platelet‐rich fibrin or collagen membranes for treating unfavorable periodontal infrabony defects: Randomized non‐inferiority trial	19
Long‐term clinical outcomes of periodontal regeneration with enamel matrix derivative: A retrospective cohort study with a mean follow‐up of 10 years	18
Alveolar ridge preservation reduces the need for ancillary bone augmentation in the context of implant therapy	18
Interproximal attachment gain: The challenge of periodontal regeneration	18
Efficacy of biologics in root coverage and gingival augmentation therapy: An American Academy of Periodontology best evidence systematic review and network meta‐analysis	18
Treatment of periodontal intrabony defects using bovine porous bone mineral and guided tissue regeneration with/without platelet‐rich fibrin: A randomized controlled clinical trial	18
Clustering by periodontitis‐associated factors: A novel application to NHANES data	18
The “oral” history of COVID‐19: Primary infection, salivary transmission, and post‐acute implications	17
Porphyromonas gingivalis, the most influential pathogen in red‐complex bacteria: A cross‐sectional study on the relationship between bacterial count and clinical periodontal status in Japan	17
Association of hyaluronic acid with a deproteinized bovine graft improves bone repair and increases bone formation in critical‐size bone defects	17
Impact of systemic probiotics as adjuncts to subgingival instrumentation on the oral‐gut microbiota associated with periodontitis: A randomized controlled clinical trial	17
Fusobacterium nucleatum aggravates ulcerative colitis through promoting gut microbiota dysbiosis and dysmetabolism	17
Biome‐microbiome interactions in peri‐implantitis: A pilot investigation	16
Comparisons of various anthropometric indexes with localized Stage II/III periodontitis in young adults: The CHIEF oral health study	16
Efficacy of an Er:YAG laser in the decontamination of dental implant surfaces: An in vitro study	16
Periodontal inflammation and distinct inflammatory profiles in saliva and gingival crevicular fluid compared with serum and joints in rheumatoid arthritis patients	16
Agreement among international periodontal experts using the 2017 World Workshop classification of periodontitis	16
Prevalence and antimicrobial susceptibility of Gram‐negative bacilli in subgingival biofilm associated with periodontal diseases	15
Soft tissue augmentation with a volume‐stable collagen matrix or an autogenous connective tissue graft at implant sites: Five‐year results of a randomized controlled trial post implant loading	15
The impact of a change in classification criteria on the prevalence of peri‐implantitis: A cross‐sectional analysis	15
Long term comparison of the prognostic performance of PerioRisk, periodontal risk assessment, periodontal risk calculator, and staging and grading systems	15
Epidemiological and sociodemographic transitions of severe periodontitis incidence, prevalence, and disability‐adjusted life years for 21 world regions and globally from 1990 to 2019: An age‐period‐co	15
Impact of mucosal phenotype on marginal bone levels around tissue level implants: A prospective controlled trial	15
Impact of adjunctive procedures on recombinant human fibroblast growth factor‐2–mediated periodontal regeneration therapy: A retrospective study	15
Peri‐implant marginal mucosa defects: Classification and clinical management	14
The virulence factor GroEL directs the osteogenic and adipogenic differentiation of human periodontal ligament stem cells through the involvement of JNK/MAPK and NF‐κB signaling	14
Gingival landmarks and cutting points for gingival phenotype determination: A clinical and tomographic cross‐sectional study	14
Subgingival microbiota in overweight and obese young adults with no destructive periodontal disease	14
Combined association of cognitive impairment and poor oral health on mortality risk in older adults: Results from the NHANES with 15 years of follow‐up	14
Antibiofilm effect of ozonized physiological saline solution on peri‐implant–related biofilm	14
Diagnostic accuracy of severe periodontitis case definitions: Comparison of the CDC/AAP, EFP/AAP, and CPI criteria	14
Periodontitis and its higher levels of severity are associated with the triglyceride/high density lipoprotein cholesterol ratio	14
Maternal periodontal status, oral inflammatory load, and systemic inflammation are associated with low infant birth weight	14
Tooth loss in periodontally compromised patients: Retrospective long‐term results 10 years after active periodontal therapy – tooth‐related outcomes	14
Periodontitis prevalence and severity in inflammatory bowel disease: A case–control study	13
The 2018 classification of periodontal diseases: Its predictive value for tooth loss	13
Hypoxia stimulates collagen hydroxylation in gingival fibroblasts and periodontal ligament cells	13
Impact of the periodontal phenotype in premolar and molar sites on bone loss following full‐thickness mucoperiosteal flap: A 1‐year prospective clinical trial	13
Autophagy upregulates inflammatory cytokines in gingival tissue of patients with periodontitis and lipopolysaccharide‐stimulated human gingival fibroblasts	13

Validation of the Hospital Anxiety and Depression Scale and the Perceived Stress Scale and psychological features in patients with periodontitis	13
Single gingival recession associated with non‐carious cervical lesion treated by partial restoration and coronally advanced flap with or without xenogenous collagen matrix: A randomized clinical trial	12
The association between periodontitis and lung function: Results from the National Health and Nutrition Examination Survey 2009 to 2012	12
J‐shaped association between systemic immune‐inflammation index and periodontitis: Results from NHANES 2009–2014	12
Metformin accelerates wound healing by Akt phosphorylation of gingival fibroblasts in insulin‐resistant prediabetes mice	12
Randomized, controlled, clinical trial to evaluate a xenogeneic collagen matrix as an alternative to free gingival grafting for oral soft tissue augmentation: A 6‐ to 8‐year follow‐up	12
Factors influencing the prevalence of peri‐implantitis in implants inserted in augmented maxillary sinuses: A multicenter cross‐sectional study	12
Bacterial resistance to minocycline after adjunctive minocycline microspheres during periodontal maintenance: A randomized clinical trial	12
BMP4 micro‐immunotherapy increases collagen deposition and reduces PGE2 release in human gingival fibroblasts and increases tissue viability of engineered 3D gingiva under inflammatory conditions	12
Comparison of two types of xenogeneic matrices to treat single gingival recessions: A randomized clinical trial	12
Association of enhanced circulating trimethylamine N‐oxide with vascular endothelial dysfunction in periodontitis patients	12
Melatonin improves periodontitis‐induced kidney damage by decreasing inflammatory stress and apoptosis in rats	12
The effects of a novel non‐invasive application of platelet‐rich fibrin on periodontal clinical parameters and gingival crevicular fluid transforming growth factor‐β and collagen‐1 levels: A randomize	12
Evaluation of galectin‐3, peptidylarginine deiminase‐4, and tumor necrosis factor‐α levels in gingival crevicular fluid for periodontal health, gingivitis, and Stage III Grade C periodontitis: A pilot	12
Ion release and local effects of titanium metal particles from dental implants: An experimental study in rats	12
Diagnostic potential of peri‐implant crevicular fluid microRNA‐21‐3p and microRNA‐150‐5p and extracellular vesicles in peri‐implant diseases	11
An accuracy study of the clinical diagnosis of periodontitis in pregnant women	11
Probiotic Lactobacillus rhamnosus EM1107 prevents hyperglycemia, alveolar bone loss, and inflammation in a rat model of diabetes and periodontitis	11
Role of YAP1 gene in proliferation, osteogenic differentiation, and apoptosis of human periodontal ligament stem cells induced by TNF‐α	11
Antioxidant effect of enamel matrix derivative for early phase of periodontal tissue regeneration in diabetes	11
Gremlin aggravates periodontitis via activation of the nuclear factor‐kappa B signaling pathway	11
Relationship between periodontitis and risk of cardiovascular disease: Insights from the Tromsø Study	11
Inhibition of yes‐associated protein dephosphorylation prevents aggravated periodontitis with occlusal trauma	11
Therapeutic effect of fluvastatin on medication‐related osteonecrosis of the jaw	10
The association of mandibular third molar impaction with the dental and periodontal lesions in the adjacent second molars	10
On the value of the 2017 classification of phenotype and gingival recessions	10
Facial mucosal level of single immediately placed implants with either immediate provisionalization or delayed restoration: An intermediate‐term study	10
Patient‐reported outcomes of palatal donor site healing using four different wound dressing modalities following free epithelialized mucosal grafts: A four‐arm randomized controlled clinical trial	10
Are colored periodontal probes reliable to classify the gingival phenotype in terms of gingival thickness?	10
Salivary and serum concentrations of monocyte chemoattractant protein‐1, macrophage inhibitory factor, and fractalkine in relation to rheumatoid arthritis and periodontitis	10
Extending the vitamin D pathway to vitamin D3and CYP27A1 in periodontal ligament cells	10
Association between periodontitis and metabolic syndrome in the Hamburg City Health Study	10
Risk factors, diagnosis, and treatment of peri‐implantitis: A cross‐cultural comparison of U.S. and European periodontists’ considerations	10
The correlation between history of periodontitis according to staging and grading and the prevalence/severity of peri‐implantitis in patients enrolled in maintenance therapy	10
Effect of non‐surgical periodontal treatment on salivary and serum biomarkers in Stage III Grade B and C periodontitis	10
Poor oral hygiene behavior is associated with an increased risk of gastric cancer: A population‐based case‐control study in China	10
Significance of barrier membrane on the reconstructive therapy of peri‐implantitis: A randomized controlled trial	9
Adjunctive effects of photodynamic therapy using indocyanine green in residual pockets during periodontal maintenance therapy: A split‐mouth randomized controlled trial	9
Prevalence and risk indicators of peri‐implant diseases in a group of Moroccan patients	9
Multiplicative effect of stress and poor sleep quality on periodontitis: A university‐based cross‐sectional study	9
Occlusal trauma is associated with periodontitis: A retrospective case‐control study	9
Efficacy of a harvest graft substitute for recession coverage and soft tissue volume augmentation: A randomized controlled trial	9
Antimicrobial susceptibility and virulence of Enterococcus spp. isolated from periodontitis‐associated subgingival biofilm	9
The use of probiotics can reduce the severity of experimental periodontitis in rats with metabolic syndrome: An immunoenzymatic and microtomographic study	9
Porphyromonas gingivalis infection alters Nrf2‐phase II enzymes and nitric oxide in primary human aortic endothelial cells	9
Periodontal and caries status in unexplained female infertility: A case–control study	9
Genome‐wide DNA (hydroxy) methylation reveals the individual epigenetic landscape importance on osteogenic phenotype acquisition in periodontal ligament cells	9
Clinical, histological, immunohistochemical, and biomolecular analysis of hyaluronic acid in early wound healing of human gingival tissues: A randomized, split‐mouth trial	9
Influence of vestibular depth on the outcomes of root coverage therapy: A prospective case series study	9
Mid‐term outcomes and periodontal prognostic factors of autotransplanted third molars: A retrospective cohort study	9
Connective tissue growth factor promotes cell‐to‐cell communication in human periodontal ligament stem cells via MAPK and PI3K pathway	9
SARS‐CoV‐2 RNA in dental biofilms: Supragingival and subgingival findings from inpatients in a COVID‐19 intensive care unit	9
The spatial and temporal trends of severe periodontitis burden in Asia, 1990–2019: A population‐based epidemiological study	9
Compressive force regulates cementoblast migration via downregulation of autophagy	8
Clinical evaluation of impact of periodontal phenotype on the outcome of open flap debridement in patients with chronic periodontitis: A comparative interventional study	8
A Mendelian randomization study on the effect of 25‐hydroxyvitamin D levels on periodontitis	8
Volumetric assessment of changes in the alveolar ridge dimension following guided bone regeneration using a combination freeze‐dried bone allograft with collagen membrane or novel resorbable scaffold:	8
The effect of 3‐D printed polylactic acid scaffold with and without hyaluronic acid on bone regeneration	8
Recombinant thrombomodulin lectin‐like domain attenuates Porphyromonas gingivalis lipopolysaccharide‐induced osteoclastogenesis and periodontal bone resorption	8
Chemerin/ChemR23 regulates cementoblast function and tooth resorption in mice via inflammatory factors	8
Clinical effects of the adjunctive use of polynucleotide and hyaluronic acid‐based gel in the subgingival re‐instrumentation of residual periodontal pockets: A randomized, split‐mouth clinical trial	8
Relationship between supracrestal soft tissue dimensions and other periodontal phenotypic features: A cross‐sectional study	8
NELL1 augments osteogenesis and inhibits inflammation of human periodontal ligament stem cells induced by BMP9	8
Association between periodontal disease, tooth extraction, and medication‐related osteonecrosis of the jaw in women receiving bisphosphonates: A national cohort‐based study	8
Exploring the relationship among dental caries, nutritional habits, and peri‐implantitis	8
Association between gestational diabetes mellitus and periodontitis via the effect of reactive oxygen species in peripheral blood cells	8
Periodontitis is a potential risk factor for transient ischemic attack and minor ischemic stroke in young adults: A nationwide population‐based cohort study	8
The additive effect of periodontitis with hypertension on risk of systemic disease and mortality	8
Racial and ethnic disparities in periodontal health among adults seeking dental care in rural North Carolina communities: A retrospective study	8
Evaluation of stress, serum, and salivary ghrelin and cortisol levels in smokers and non‐smokers with Stage III periodontitis: A cross‐sectional study	8
Comparative analysis of proliferative and multilineage differentiation potential of human periodontal ligament stem cells from maxillary and mandibular molars	8
Association between peri‐implantitis and cardiovascular diseases: A case‐control study	8
Periodontal risk score: Initiation and model validation for 6,762 teeth	8
Evaluation of the accuracy of soft tissue thickness measurements with three different methodologies: An in vitro study	8
Tooth loss and radiographic bone loss in patients without regular supportive care: A retrospective study	8
Leucine‐rich alpha‐2 glycoprotein (LRG): A novel acute phase protein expressed in Stage 3 Grade C periodontitis before and after periodontal therapy	8
Fabrication and evaluation of antimicrobial biomimetic nanofiber coating for improved dental implant bioseal: An in vitro study	8
Pro‐inflammatory profiles in cardiovascular disease patients with peri‐implantitis	8
The effectiveness of using the perioscope as an adjunct to non‐surgical periodontal therapy: Clinical and radiographic results	8
Efficacy of Nd:YAG laser‐assisted periodontal therapy for the management of periodontitis: A double‐blind split‐mouth randomized controlled clinical trial	8

Periodontal conditions and incident dementia: A nationwide Swedish cohort study	8
Association between intracranial carotid artery calcifications and periodontitis: A cone‐beam computed tomography study	8
The causal effect of life course adiposity on periodontitis: A Mendelian randomization study	7
Effect of individual and neighborhood social capital on gingival bleeding in children: A 7‐year cohort study	7
Long‐term stability of regenerative periodontal surgery and orthodontic tooth movement in stage IV periodontitis: 10‐year data of a retrospective study	7
Clinical, radiographic, and patient‐centered outcomes after use of enamel matrix proteins for the treatment of intrabony defects in patients with aggressive periodontitis: A 12‐month multicenter clini	7
Periodontitis prevalence and severity in an African population: A cross‐sectional study in the Greater Accra Region of Ghana	7
Effects of periodontitis and periodontal treatment on systemic inflammatory markers and metabolic profile in obese and non‐obese rats	7
Longitudinal changes in subgingival biofilm composition following periodontal treatment	7
Comparing the histological assessment following ridge preservation using a composite bovine‐derived xenograft versus an alloplast hydroxyapatite‐sugar cross‐linked collagen matrix	7
Comparative evaluation of 1% melatonin gel in the treatment of intrabony defect: A randomized controlled clinical trial	7
Effects of hyaluronic acid and deproteinized bovine bone mineral with 10% collagen for ridge preservation in compromised extraction sockets	7
Antibody response to BNT162b2 mRNA vaccine in gingival crevicular fluid	7
Association of periodontitis, missing teeth, and oral hygiene behaviors with the incidence of hypertension in middle‐aged and older adults in Korea: A 10‐year follow‐up study	7
Spent culture supernatant of Streptococcus gordonii mitigates inflammation of human periodontal cells and inhibits proliferation of pathogenic oral microbes	7
Prognostic performance of the 2017 World Workshop classification on staging and grading of periodontitis compared with the British Society of Periodontology's implementation	7
Association between tooth loss, chronic conditions, and common risk factors: Results from the 2019 Brazilian Health Survey	7
Gender differences in immunological response of African‐American juveniles with Grade C molar incisor pattern periodontitis	7
Effects of collagen membranes and bone substitute differ in periodontal ligament cell microtissues and monolayers	7
Methods to mitigate infection spread from aerosol‐generating dental procedures	7
Diagnostic reproducibility of the 2018 Classification of Gingival Recession Defects and Gingival Phenotype: A multicenter inter‐ and intra‐examiner agreement study	7
Reliability assessment of the classification for facial peri‐implant soft tissue dehiscence/deficiencies (PSTDs): A multi‐center inter‐rater agreement study of different skill‐level practitioners	7
Evaluation of length and location of the maxillary sinus intraosseous artery using computerized tomography	7
Accelerated alveolar bone loss in a mouse model of inflammatory bowel disease and its relationship with intestinal inflammation	7