Journal of Periodontal Research

Article	Citations
Hyperglycemia modulates M1/M2 macrophage polarization via reactive oxygen species overproduction in ligature‐induced periodontitis	118
Analysis of galectin‐3 levels as a source of coronary heart disease risk during periodontitis	76
Impact of periodontitis on gingival crevicular fluid miRNAs profiles associated with cardiovascular disease risk	52
Porphyromonasgingivalis survival skills: Immune evasion	46
Ingestion of Porphyromonas gingivalis exacerbates colitis via intestinal epithelial barrier disruption in mice	45
Deep learning in periodontology and oral implantology: A scoping review	40
Mechanisms involved in regulation of periodontal ligament cell production of pro‐inflammatory cytokines: Implications in periodontitis	37
The Th17/Treg cell balance: crosstalk among the immune system, bone and microbes in periodontitis	35
The emerging role of small extracellular vesicles in saliva and gingival crevicular fluid as diagnostics for periodontitis	33
Metabolomics of gingival crevicular fluid to identify biomarkers for periodontitis: A systematic review with meta‐analysis	32
Metagenomic sequencing provides new insights into the subgingival bacteriome and aetiopathology of periodontitis	28
Curcumin: A review of experimental studies and mechanisms related to periodontitis treatment	28
Hydrophilic titanium surface modulates early stages of osseointegration in osteoporosis	25
Heat‐not‐burn tobacco (IQOS), oral fibroblasts and keratinocytes: cytotoxicity, morphological analysis, apoptosis and cellular cycle. An in vitro study	25
Exosomes from dental pulp cells attenuate bone loss in mouse experimental periodontitis	24
MiR‐153‐3p inhibits osteogenic differentiation of periodontal ligament stem cells through KDM6A‐induced demethylation of H3K27me3	23
Autophagy and its significance in periodontal disease	22
Association between TNF‐α G‐308A (rs1800629) polymorphism and susceptibility to chronic periodontitis and type 2 diabetes mellitus: A meta‐analysis	21
Resveratrol enhances bone formation by modulating inflammation in the mouse periodontitis model	20
Impaired dental implant osseointegration in rat with streptozotocin‐induced diabetes	20
Mesenchymal stem cell‐derived small extracellular vesicles as cell‐free therapy: Perspectives in periodontal regeneration	20
A deficiency of Dec2 triggers periodontal inflammation and pyroptosis	19
NCOA4‐mediated ferritinophagy promoted inflammatory responses in periodontitis	19
Does the use of omega‐3 fatty acids as an adjunct to non‐surgical periodontal therapy provide additional benefits in the treatment of periodontitis? A systematic review and meta‐analysis	19
IL‐1B(3954) polymorphism and red complex bacteria increase IL‐1β (GCF) levels in periodontitis	18

Macro and trace elements signature of periodontitis in saliva: A systematic review with quality assessment of ionomics studies	18
Adjunctive systemic antimicrobials in the treatment of chronic periodontitis: A systematic review and network meta‐analysis	18
Relationship between periodontitis and microangiopathy in type 2 diabetes mellitus: a meta‐analysis	18
Periodontitis and edentulism as risk indicators for mortality: Results from a prospective cohort study with 20 years of follow‐up	18
Interdental and subgingival microbiota may affect the tongue microbial ecology and oral malodour in health, gingivitis and periodontitis	17
Interruption of regular dental visits during the COVID‐19 pandemic due to concerns regarding dental visits was associated with periodontitis in Japanese office workers	17
Ability of matrix metalloproteinase‐8 biosensor, IFMA, and ELISA immunoassays to differentiate between periodontal health, gingivitis, and periodontitis	17
The role of endoplasmic reticulum stress in the pathophysiology of periodontal disease	17
Diagnostic accuracy of active matrix metalloproteinase‐8 point‐of‐care test for the discrimination of periodontal health status: Comparison of saliva and oral rinse samples	17
Membrane vesicles from periodontal pathogens and their potential roles in periodontal disease and systemic illnesses	16
The role of mitochondrial dysfunction in periodontitis: From mechanisms to therapeutic strategy	16
PTH/PTHrP in controlled release hydrogel enhances orthodontic tooth movement by regulating periodontal bone remodaling	16
The role of vitamin D in periodontal health and disease	15
Abnormal mitochondrial structure and function are retained in gingival tissues and human gingival fibroblasts from patients with chronic periodontitis	15
Sirtuin 3 deficiency exacerbates age‐related periodontal disease	15
Association between periodontitis and the Mediterranean diet in young Moroccan individuals	15
Hyperglycemia accelerates inflammaging in the gingival epithelium through inflammasomes activation	14
Influence of anti‐rheumatic agents on the periodontal condition of patients with rheumatoid arthritis and periodontitis: A systematic review and meta‐analysis	14
Oral microbiota and atherothrombotic carotid plaque vulnerability in periodontitis patients. A cross‐sectional study	14
New putative periodontopathogens and periodontal health‐associated species: A systematic review and meta‐analysis	14
Periodontitis and Systemic Lupus Erythematosus: A systematic review and meta‐analysis	14
The miR‐155‐5p inhibits osteoclast differentiation through targeting CXCR2 in orthodontic root resorption	13
Inhibition of acid sphingomyelinase by imipramine abolishes the synergy between metabolic syndrome and periodontitis on alveolar bone loss	13
Pro‐inflammatory cytokine interleukin‐6‐induced hepcidin, a key mediator of periodontitis‐related anemia of inflammation	13
Long‐term exposure to cigarette smoke influences characteristics in human gingival fibroblasts	13
Study on the role of pyroptosis in bone resorption induced by occlusal trauma with or without periodontitis	13
Proteoglycans in the periodontium: A review with emphasis on specific distributions, functions, and potential applications	13
Wound healing in periodontal disease induces macrophage polarization characterized by different arginine‐metabolizing enzymes	13
The role of strontium ranelate and guided bone regeneration in osteoporotic and healthy conditions	13
Herpes simplex virus type 1 in subgingival plaque and periodontal diseases. Meta‐analysis of observational studies	12
Roles of trained immunity in the pathogenesis of periodontitis	12
Pyroptosis may play a crucial role in modifications of the immune microenvironment in periodontitis	12
ZNF718, HOXA4, and ZFP57 are differentially methylated in periodontitis in comparison with periodontal health: Epigenome‐wide DNA methylation pilot study	12
Molecular profiling of intrabony defects' gingival crevicular fluid	12
Potential biomarkers reflecting inflammation in patients with severe periodontitis: Fractalkine (CX3CL1) and its receptor (CX3CR1)	12
Long non‐coding RNAs: Emerging roles in periodontitis	12
LiCl‐induced immunomodulatory periodontal regeneration via the activation of the Wnt/β‐catenin signaling pathway	12
Association of probable bruxism with periodontal status: A cross‐sectional study in patients seeking periodontal care	11
Survival rate and potential risk indicators of implant loss in non‐smokers and systemically healthy periodontitis patients: An up to 9‐year retrospective study	11
Identification and integrated analysis of differentially expressed long non‐coding RNAs associated with periodontitis in humans	11
Oral‐gut bacterial profiles discriminate between periodontal health and diseases	11
Is TIMP‐1 a biomarker for periodontal disease? A systematic review and meta‐analysis	11
Cross‐sectional analysis of the association of periodontitis with carotid intima media thickness and atherosclerotic plaque in the Hamburg City health study	11
An in vitro study into three different PRF preparations for osteogenesis potential	11
Generation of a novel model of bioengineered human oral mucosa with increased vascularization potential	11
Poly(lactic acid/caprolactone) bilayer membrane blocks bacterial penetration	10
Enamel matrix derivative effects on palatal mucosa wound healing: Randomized clinical trial	10
Gingival crevicular fluid lipocalin‐2 and semaphorin3A in stage III periodontitis: Non‐surgical periodontal treatment effects	10
Periodontitis links to concurrent systemic comorbidities among ‘self‐perceived health’ individuals	10
The effect of Porphyromonas gingivalis on the gut microbiome of mice in relation to aging	10

Simvastatin loaded chitosan guided bone regeneration membranes stimulate bone healing	10
Cross‐sectional comparisons of subgingival microbiome and gingival fluid inflammatory cytokines in periodontally healthy vegetarians versus non‐vegetarians	10
Phytocannabinoids regulate inflammation in IL‐1β‐stimulated human gingival fibroblasts	10
Differences in chlorhexidine mouthrinses formulations influence the quantitative and qualitative changes in in‐vitro oral biofilms	9
Optimizing citric acid protocol to control implant‐related infections: Anin vitroandin situstudy	9
MZB1 targeted by miR‐185‐5p inhibits the migration of human periodontal ligament cells through NF‐κB signaling and promotes alveolar bone loss	9
A novel adiponectin receptor agonist (AdipoAI) ameliorates type 2 diabetes‐associated periodontitis by enhancing autophagy in osteoclasts.	9
microRNAs in inflammatory alveolar bone defect: A review	9
Regular dental visits, periodontitis, tooth loss, and atherosclerosis: The Ohasama study	9
Regeneration of rat periodontium by cementum protein 1‐derived peptide	9
Porphyromonas gingivalis facilitated the foam cell formation via lysosomal integral membrane protein 2 (LIMP2)	9
LncRNA DCST1‐AS1 inhibits PDLCs’ proliferation in periodontitis and may bind with miR‐21 precursor to upregulate PLAP‐1	9
Comparative proteomic analysis of dental cementum from deciduous and permanent teeth	9
Cytokines in gingival crevicular fluid in elderly rheumatoid arthritis patients in a population‐based cross‐sectional study: RANTES was associated with periodontitis	8
Association among periodontitis severity, anti‐agalactosyl immunoglobulin G titer, and the disease activity of rheumatoid arthritis	8
Wnt4 regulates bone metabolism through IKK‐NF‐κB and ROCK signaling under occlusal traumatic periodontitis	8
Different applications forms of green tea (Camelliasinensis (L.) Kuntze) for the treatment of periodontitis: a systematic review and meta‐analysis	8
Melatonin promoted osteogenesis of human periodontal ligament cells by regulating mitochondrial functions through the translocase of the outer mitochondrial membrane 20	8
Antioxidants protect against gingival overgrowth induced by cyclosporine A	8
A population‐based cross‐sectional study of the association between periodontitis and arterial stiffness among the older Japanese population	8
CircRNA Lrp6 promotes cementoblast differentiation via miR‐145a‐5p/Zeb2 axis	8
Lactic acid bacteria prevent both periodontitis and atherosclerosis exacerbated by periodontitis in spontaneously hyperlipidemic mice	8
Variations in IgG antibody subclass responses to oral bacteria: Effects of periodontal disease and modifying factors	8
The accuracy of probing, ultrasound and cone‐beam CT scans for determining the buccal bone plate dimensions around oral implants – A systematic review	8
Identification of potentially functional circRNAs and prediction of circRNA‐miRNA‐mRNA regulatory network in periodontitis: Bridging the gap between bioinformatics and clinical needs	8
Abnormal hsa_circ_0003948 expression affects chronic periodontitis development by regulating miR‐144‐3p/NR2F2/PTEN signaling	8
Remnant oral biofilm and microorganisms after autoclaving sterilization of retrieved healing abutments	8
Iron accumulation is associated with periodontal destruction in a mouse model of HFE‐related haemochromatosis	8
In vitro evaluation of the effect of the electronic cigarette aerosol, Cannabis smoke, and conventional cigarette smoke on the properties of gingival fibroblasts/gingival mesenchymal stem cells	7
Impaired function of epithelial plakophilin‐2 is associated with periodontal disease	7
Covid‐19 and SARS‐CoV‐2 infection in periodontology: A narrative review	7
Systemic administration of cytotoxic T lymphocyte‐associated antigen 4 (CTLA‐4)‐Ig abrogates alveolar bone resorption in induced periodontitis through inhibition of osteoclast differentiation and acti	7
Polarization of human gingival fibroblasts by Th1‐, Th2‐, Th17‐, and Treg‐derived cytokines	7
Changes in serum omega fatty acids on a Mediterranean diet intervention in patients with gingivitis: An exploratory study	7
IFN‐γ or IL‐4 polarization impacts the response of gingival fibroblasts to oral bacteria	7
Canonical and noncanonical pyroptosis are both activated in periodontal inflammation and bone resorption	7
Short‐term efficacy of a gel containing propolis extract, nanovitamin C and nanovitamin E on peri‐implant mucositis: A double‐blind, randomized, clinical trial	7
Alcohol use disorders are associated with higher prevalence of periodontitis in a rural area of Brazil	7
Hyaluronic acid enhances cell migration, viability, and mineralized tissue‐specific genes in cementoblasts	7
Adjunctive Er:YAG laser in non‐surgical periodontal therapy of patients with inadequately controlled type 2 diabetes mellitus: A split‐mouth randomized controlled study	7
Salivary histone deacetylase in periodontal disease: A cross‐sectional pilot study	7
Validity of a combination of periodontal pathogens and salivary biomarkers as predictors of periodontitis	7
TNFα expression by Porphyromonas gingivalis‐stimulated macrophages relies on Sirt1 cleavage	7
Effect of vitamin D3 on the osteogenic differentiation of human periodontal ligament stromal cells under inflammatory conditions	7
Pyrophosphate inhibits periodontal ligament stem cell differentiation and mineralization through MAPK signaling pathways	7
Influence of periodontitis on levels of autoantibodies in rheumatoid arthritis patients: A systematic review	7
Effects of periodontal cells‐derived extracellular vesicles on mesenchymal stromal cell function	7
Six miRNA expressions in the saliva of smokers and non‐smokers with periodontal disease	7
ODAM promotes junctional epithelium‐related gene expression via activation of WNT1 signaling pathway in an ameloblast‐like cell line ALC	7
Protective mechanisms of Taiwanese green propolis toward high glucose‐induced inflammation via NLRP3 inflammasome signaling pathway in human gingival fibroblasts	7
Meta‐analysis of the association between periodontal disease, periodontal treatment and carotid intima–media thickness	7
Periodontal tissue engineering using an apatite/collagen scaffold obtained by a plasma‐ and precursor‐assisted biomimetic process	7
Identification of hub genes related to immune cell infiltration in periodontitis using integrated bioinformatic analysis	7
Distribution of neutrophil and monocyte/macrophage populations induced by the CXCR4 inhibitor AMD3100 in blood and periodontal tissue early after periodontitis induction	7
MicroRNA sequence and function analysis in peri‐implantitis and periodontitis: An animal study	7
Semaphorin 3A attenuates the hypoxia suppression of osteogenesis in periodontal ligament stem cells	7
Expression of Wnt signaling agonists and antagonists in periodontitis and healthy subjects, before and after non‐surgical periodontal treatment: A systematic review	6
Renal alterations caused by ligature‐induced periodontitis persist after ligature removal in rats	6
Chalcone T4, a novel chalconic compound, inhibits inflammatory bone resorption in vivo and suppresses osteoclastogenesis in vitro	6
Effects of titanium dioxide microparticles and nanoparticles on cytoskeletal organization, cell adhesion, migration, and proliferation in human gingival fibroblasts in the presence of lipopolysacchari	6
LncRNA LOXL1‐AS1 inhibits proliferation of PDLSCs and downregulates IL‐1β in periodontitis patients	6
Effect of quadrantwise versus full‐mouth subgingival instrumentation on clinical and microbiological parameters in periodontitis patients: A randomized clinical trial	6
Effects of combined use of recombinant human fibroblast growth factor‐2 and β‐tricalcium phosphate on ridge preservation in dehiscence bone defects after tooth extraction: A split‐mouth study in dogs	6
Salivary levels of last generation specific pro‐resolving lipid mediators (SPMs) (protectin and maresin) in patients with cardiovascular and periodontal disease: A case‐control study	6
Design, synthesis, and evaluation of mono‐carbonyl analogues of curcumin (MCACs) as potential antioxidants against periodontitis	6
The periodontal ligament, temperature‐sensitive ion channels TRPV1–4, and the mechanosensitive ion channels Piezo1 and 2: A Nobel connection	6
Quercetin promotes autophagy to alleviate cigarette smoke‐related periodontitis	6
Higher expression of Th1/Th2‐related cytokines in the intestine of Wistar rats with ligature‐induced periodontitis	6
Association between Mediterranean diet and periodontitis among US adults: The mediating roles of obesity indicators	6
Cannabidiol attenuates periodontal inflammation through inhibiting TLR4/NF‐κB pathway	6
Salivary levels of BAFF, TWEAK, and soluble CD163 and salivary arginase activity before and after periodontal treatment	6
Obesity influences the proteome of periodontal ligament tissues following periodontitis induction in rats	6
Semaphorin 3A protects against alveolar bone loss during orthodontic tooth movement in mice with periodontitis	6
Demystifying the connection between periodontal disease and chronic kidney disease – An umbrella review	6
Low association between bleeding on probing propensity and the salivary aMMP‐8 levels in adolescents with gingivitis and stage I periodontitis	6
Expression of periodontitis susceptibility genes in human gingiva using single‐cell RNA sequencing	6
Periodontal disease inequities among Indigenous populations: A systematic review and meta‐analysis	6
Periodontal inflammation triggers a site‐specific and wide radius of calcium metabolic effects on alveolar bone	6
High‐mobility group box 1 released by traumatic occlusion accelerates bone resorption in the root furcation area in mice	6
Decellularized matrix could affect the proliferation and differentiation of periodontal ligament stem cells in vitro	6

Regulation of osteogenesis in bone marrow‐derived mesenchymal stem cells via histone deacetylase 1 and 2 co‐cultured with human gingival fibroblasts and periodontal ligament cells

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