Journal of Pathology

Article	Citations
Artificial intelligence to identify genetic alterations in conventional histopathology	97
Escape from senescence: molecular basis and therapeutic ramifications	85
CXCR4 mediates leukemic cell migration and survival in the testicular microenvironment	79
A new FGF15/19‐mediated gut‐to‐heart axis controls cardiac hypertrophy	74
Integration of peripheral blood‐ and tissue‐based biomarkers of response to immune checkpoint blockade in urothelial carcinoma	73
Issue Information	67
Collagen VI promotes recovery from colitis by inducing lymphangiogenesis and drainage of inflammatory cells	66
Spatial profiling of ANO7 in prostate tissue: links to AR‐signalling‐associated lipid metabolism and inflammation	63
Breathing in danger: how particulate matter pollution is putting the public at risk of lung cancer†	60
Ovarian high‐grade serous carcinoma cells with low SMARCA4 expression and high SMARCA2 expression contribute to platinum resistance	58
Novel prognostication biomarker adipophilin reveals a metabolic shift in uveal melanoma and new therapeutic opportunities	56
The association between the tumor immune microenvironments and clinical outcome in low‐grade, early‐stage endometrial cancer patients	52
‘Know thyself’ – host factors influencing cancer response to immune checkpoint inhibitors	51
Intravenous iron treatment fuels chronic kidney disease‐induced arterial media calcification in rats	50
High‐resolution and quantitative spatial analysis reveal intra‐ductal phenotypic and functional diversification in pancreatic cancer	46
Identification of actionable targets using DEPArray ‐based sorting of pure carcinoma and stromal populations from formalin‐fixed paraffin‐embedded ti	45
Presence of Tim3+ and PD‐1+CD8+T cells identifies microsatellite stable colorectal carcinomas with immune exhaustion and di	45
Field cancerization in breast cancer	44
	41
CRISPR –Cas9 screening identifies the role of FER as a tumor suppressor	41
Silencing GRHL3 promotes multiple organ distant metastasis of lung squamous cell carcinoma cells by enhancing SOX2 stability via SIRT1	40
Identification of tumour‐infiltrating myeloid subsets associated with overall survival in lung squamous cell carcinoma	40
The E2F1–HOXB9/PBX2–CDK6 axis drives gastric tumorigenesis and serves as a therapeutic target in gastric cancer	37
Platelet C3G protects from liver fibrosis, while enhancing tumor growth through regulation of the immune response	37
In high‐grade ovarian carcinoma, platinum‐sensitive tumor recurrence and acquired‐resistance derive from quiescent residual cancer cells that overexpress CRYAB, CEACAM6, and	37

Pseudobudding: ruptured glands do not represent true tumor buds	36
Human scattered tubular cells represent a heterogeneous population of glycolytic dedifferentiated proximal tubule cells	35
	33
Integrating computational pathology and proteomics to address tumor heterogeneity	33
KMT2D deficiency potentiates antitumor immunity and sensitizes immune checkpoint blockade in urologic cancers	33
Genomic features of Helicobacter pylori‐naïve diffuse‐type gastric cancer	33
Development of a multi‐scanner facility for data acquisition for digital pathology artificial intelligence	32
Issue Information	31
Integrative analysis of genomic and transcriptomic data of normal, tumour, and co‐occurring leukoplakia tissue triads drawn from patients with gingivobuccal oral cancer identifies signatures of tumour	31
Prediction of coexisting invasive carcinoma on ductal carcinoma in situ (DCIS) lesions by mass spectrometry imaging	31
On the origin of gastric tumours: analysis of a case with intramucosal gastric carcinoma and oxyntic gland adenoma	31
Minigene‐based splicing analysis and ACMG/AMP‐based tentative classification of 56 ATM variants	30
Adrenomedullin2 stimulates progression of thyroid cancer in mice and humans under nutrient excess conditions	29
	27
PCDHGC3 hypermethylation as a potential biomarker of intestinal neuroendocrine carcinomas	27
Downregulated BMP –Smad1/5/8 signaling causes emphysema via dysfunction of alveolar type II epithe	27
	27
Primary thyroid B‐cell lymphoma: molecular insights into its clonal evolution and relapse	27
Genetic and epigenetic alterations in precursor lesions of endometrial endometrioid carcinoma	27
	26
	26
	26
Tumor immune microenvironment alterations associated with progression in human intraductal papillary mucinous neoplasms	25
Integrated molecular characterization of esophageal basaloid squamous cell carcinoma: a subtype with distinct RNA expression pattern and immune characteristics, but no specific genetic muta	25
BMP signalling in colorectal cancer: losing the yin to WNTs yang	25
The earliest events in BRAF‐mutant colorectal cancer: exome sequencing of sessile serrated lesions with a tiny focus dysplasia or cancer reveals recurring mutations in two distinct p	24
PIK3CA mutation subtype delineates distinct immune profiles in gastric carcinoma	24
Issue Information	23
Canonical Kaiso target genes define a functional signature that associates with breast cancer survival and the invasive lobular carcinoma histological type	23
Lineage tracing in human tissues	23
	23
Deep learning based on hematoxylin–eosin staining outperforms immunohistochemistry in predicting molecular subtypes of gastric adenocarcinoma	23
Random forest modelling demonstrates microglial and protein misfolding features to be key phenotypic markers in C9orf72‐ALS	22
	22
Pitfalls in machine learning‐based assessment of tumor‐infiltrating lymphocytes in breast cancer: A report of the International Immuno‐Oncology Biomarker Working Group on Breast Cancer	22
Copy‐number intratumor heterogeneity increases the risk of relapse in chemotherapy‐naive stage II colon cancer	22
Somatic loss of ATM is a late event in pancreatic tumorigenesis	22
Increased expression of phosphodiesterase 4 in activated hepatic stellate cells promotes cytoskeleton remodeling and cell migration	21
Liver insulin‐like growth factor‐1 mediates effects of low‐intensity vibration on wound healing in diabetic mice	21
Caspase activation in tumour‐infiltrating lymphocytes is associated with lymph node metastasis in oral squamous cell carcinoma	21
Long‐term treatment of cancer‐prone germline PTEN mutant mice with low‐dose rapamycin extends lifespan and delays tumour development	21
Issue Information	21
Transcriptomics and proteomics reveal distinct biology for lymph node metastases and tumour deposits in colorectal cancer	21
Assessing spatial sequencing and imaging approaches to capture the molecular and pathological heterogeneity of archived cancer tissues	20
Multiregion exome sequencing indicates a monoclonal origin of esophageal spindle‐cell squamous cell carcinoma	20
DNA methylation patterns are influenced by Pax3 ::	19
C1GALT1 expression predicts poor survival in osteosarcoma and is crucial for ABCC1 transporter‐mediated doxorubicin re	19
Issue Information	19
Cell division‐dependent dissemination following E‐cadherin loss underlies initiation of diffuse‐type gastric cancer	19
Genetic alterations during the neoplastic cascade towards cholangiocarcinoma in primary sclerosing cholangitis	18

APC‐related multiple salivary gland lesions: spatial transcriptomic analysis reveals progressive WNT activation	18
Issue Information	18
Macrophages producing chondroitin sulfate proteoglycan‐4 induce neuro‐cardiac junction impairment in Duchenne muscular dystrophy	18
The state of the art for artificial intelligence in lung digital pathology	18
Pancancer cytotoxic T‐cell trapping: are neutrophil extracellular traps a viable biomarker for immunotherapy response?†	18
Expanding the clinicopathologic spectrum and genomic landscape of tumors with SMARCA2/4::CREM fusions	18
Mutation profiling in differential diagnosis between TdT‐positive high‐grade/large B‐cell lymphoma and B‐lymphoblastic leukaemia/lymphoma	18
Revisionist history uncovers a simplified molecular‐based classification of differentiated thyroid cancer	18
	18
Defining the first bona fide cell model for SMARCA4‐deficient, undifferentiated tumor	17
Issue Information	17
Spasmolytic polypeptide‐expressing metaplasia (SPEM) cell lineages can be an origin of gastric cancer	17
Re‐interpreting tumour behaviour and the tumour microenvironment as normal responses to tissue disorganisation	17
Correction to ‘Dual inhibition of the endothelin and angiotensin receptor ameliorates renal and inner ear pathologies in Alport mice’	17
Proteomic profiling identifies novel diagnostic biomarkers and molecular subtypes for mucinous tubular and spindle cell carcinoma of the kidney	17
Transcriptomic profiles of myxofibrosarcoma and undifferentiated pleomorphic sarcoma correlate with clinical and genomic features	16
Differential involvement of LUBAC‐mediated linear ubiquitination in intestinal epithelial cells and macrophages during intestinal inflammation	16
Histone deacetylase 6 inhibition attenuates pathological cardiac hypertrophy by promoting autophagy through MAP1LC3B ubiquitination	16
Cdt1 overexpression drives colorectal carcinogenesis through origin overlicensing and DNA damage	16
Fusion with type 2 macrophages induces melanoma cell heterogeneity that potentiates immunological escape from cytotoxic T lymphocytes	16
Human colonic organoids for understanding early events of familial adenomatous polyposis pathogenesis	16
Unleashing the potential of AI for pathology: challenges and recommendations	16
Divergent evolution of metachronous follicular lymphoma and extranodal marginal zone lymphoma of mucosa‐associated lymphoid tissue from a common precursor	16
Anti‐CD40L therapy prevents the formation of precursor lesions to gastric B‐cell MALT lymphoma in a mouse model	16
	16
Immune‐related gene expression signatures: a step forward in the stratification of patients with ovarian clear cell carcinoma †	15
RAF1–MEK/ERK pathway‐dependent ARL4C expression promotes ameloblastoma cell proliferation and osteoclast formation	15
UPK3A+ umbrella cell damage mediated by TLR3–NR2F6 triggers programmed destruction of urothelium in Hunner‐type interstitial cystitis/painful bladder syndrome	15
The importance of tumor microenvironment modulations in the progression of pancreatic intraductal papillary mucinous neoplasms†	15
The spectrum and significance of secondary (co‐occurring) genetic alterations in sarcomas: the hallmarks of sarcomagenesis	15
Evidence for etiologic field changes in tongue distant from tumor in patients with squamous cell carcinoma of the oral tongue	14
Consensus molecular subtype transition during progression of colorectal cancer	14
Stress testing deep learning models for prostate cancer detection on biopsies and surgical specimens	14
Tracing metastatic spread in pediatric solid tumors using copy number and targeted deep sequencing	14
Jeremy Jass Prize for Research Excellence in Pathology 2021	14
Issue Information	14
‘Experimentally‐induced anti‐myeloperoxidase vasculitis does not require properdin, MASP‐2 or bone marrow‐derived C5’	14
Issue Information	14
PI3 expression predicts recurrence after chemotherapy with DNA‐damaging drugs in gastric cancer	14
Metformin confers sensitisation to syrosingopine in multiple myeloma cells by metabolic blockage and inhibition of protein synthesis	14
Application of digital pathology‐based advanced analytics of tumour microenvironment organisation to predict prognosis and therapeutic response	14
Issue Information	14
Lack of EGFR catalytic activity in hepatocytes improves liver regeneration following DDC‐induced cholestatic injury by promoting a pro‐restorative inflammatory response	13
Nuclear pCHK1 as a potential biomarker of increased sensitivity to ATR inhibition	13
Indoleamine 2,3‐dioxygenase (IDO)‐1 and IDO‐2 activity and severe course of COVID‐19	13
Clinical significance of pancreatic ductal metaplasia	13
Fibrinogen Aα‐chain amyloidosis outbreaks in Japanese squirrels (Sciurus lis): a potential disease model	13
Issue Information	13
Issue Information	13
Local factor H production by human choroidal endothelial cells mitigates complement deposition: implications for macular degeneration	13
Genomic analysis defines distinct pancreatic and neuronal subtypes of lung carcinoid	13
	13
Enhanced diagnostic potential of CSPG4 in melanoma and nevi: a comparative study with PRAME, CDC7 and Ki67	13
Tumor‐infiltrating lymphocytes‐based subtypes and genomic characteristics of EBV‐associated lymphoepithelioma‐like carcinoma	13
Interaction of the tumor suppressor SMAD4 and WNT signaling in progression to oral squamous cell carcinoma	13
Abstracts	13
Integrative analysis of transcriptomic and metabolomic profiles reveals abnormal phosphatidylinositol metabolism in follicles from endometriosis‐associated infertility patients	13
CD27 / CD70 pathway activation in primary cutaneous CD4 + small/med	12
Extracellular vesicles arising from apoptosis: forms, functions, and applications	12
Computer‐extracted features of nuclear morphology in hematoxylin and eosin images distinguish stage II and IV colon tumors	12
Disseminated cancer cells detected by immunocytology in lymph nodes of NSCLC patients are highly prognostic and undergo parallel molecular evolution	12
Issue Information	12
Contribution of alterations in peritubular capillary density and microcirculation to the progression of tubular injury and kidney fibrosis	12
Validated biomarker assays confirm that ARID1A loss is confounded with MMR deficiency,	12
Issue Information	12
Computational pathology in cancer diagnosis, prognosis, and prediction – present day and prospects	12
Clonal dynamics of chronic myelomonocytic leukemia progression: paired‐sample comparison	12
Role of Toll‐like receptor 4 in intravascular hemolysis‐mediated injury	12
A Tc1‐ and Th1‐T‐lymphocyte‐rich tumor microenvironment is a hallmark of MSI colorectal cancer	12
Ferrostatin‐1 modulates dysregulated kidney lipids in acute kidney injury	11
	11
Issue Information	11
Comprehensive splicing analysis of the alternatively spliced CHEK2 exons 8 and 10 reveals three en	11
Dual inhibition of the endothelin and angiotensin receptor ameliorates renal and inner ear pathologies in Alport mice	11
The phospholipid flippase ATP9A enhances macropinocytosis to promote nutrient starvation tolerance in hepatocellular carcinoma	11
Oronasal mucosal melanoma is defined by two transcriptional subtypes in humans and dogs with implications for diagnosis and therapy	11
FOXL2C134W: much ado about something!†	11
Disorganisation of basement membrane zone architecture impairs melanocyte residence in vitiligo	11
	10
Super resolution of pathology images with hierarchical feature integration and local image patterns	10

Downregulation of HDAC9 by the ketone metabolite β‐hydroxybutyrate suppresses vascular calcification	10
Discoidin domain receptor 2 signaling through PIK3C2α in fibroblasts promotes lung fibrosis	10
Distinct genomic landscapes in radiation‐associated angiosarcoma compared with other radiation‐associated sarcoma histologies	10
Cell state dynamics during early stages of serous endometrial carcinoma	10
Reducing the risks of nuclear war – the role of health professionals	10
P2X4 purinergic receptors offer a therapeutic target for aggressive prostate cancer	10
NEIL3 promotes hepatoma epithelial–mesenchymal transition by activating the BRAF/MEK/ERK/TWIST signaling pathway	10
Afadin loss induces breast cancer metastasis through destabilisation of E‐cadherin to F‐actin linkage	10