OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Neuropathology and Experimental Neurology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
In This Issue	42
Transdifferentiation of metastatic melanoma into cerebellar angiosarcoma	40
Dual white matter pathology in fetal holoprosencephaly featuring concurrent malformative and destructive features: A case series	36
Extensive Postnatal Brainstem Calcification in a Premature Infant	34
In This Issue	29
Charcot Bouchard aneurysm: Case report and critical literature review	28
Diagnostic yield of postmortem brain examination following premortem brain biopsy for neoplastic and nonneoplastic disease	28
Myxoid glioneuronal tumors can harbor unusual PDGFRA alterations	25
Revealing the potential role of hsa-miR-663a in modulating the PI3K-Akt signaling pathway via miRNA microarray in spinal muscular atrophy patient fibroblast-derived iPSCs	24
Evaluation of 6 monoclonal antibodies against Ser129-phosphorylated α-synuclein: Critical role of proteinase K antigen retrieval and superior sensitivity of the D1R1R clone in human skin biopsies	23
Atorvastatin and ischemic stroke: Mechanisms and therapeutic applications	21
Plasticity of synapses innervating spinal motor neurons after spinal cord injury in rhesus monkeys	21
A novel grading system combining histological grade and CDKN2A homozygous and hemizygous deletion to predict prognosis in IDH-mutant astrocytoma	21
ANKRD22 promotes glioma proliferation, migration, invasion, and epithelial-mesenchymal transition by upregulating E2F1-mediated MELK expression	20
Tissue clearing to examine glioma complexity in 3 dimensions	20
Identification of disease-associated molecular signatures in the Prp-TDP-43A315T mouse model of ALS: Toward preclinical biomarker development	20
Aberrant accumulation of phosphorylated BRCA1 in brainstem-type and cortical-type Lewy bodies in Lewy body disease	19
YAP1::MAML2 fusion-positive high-grade neuroepithelial tumors with rhabdoid morphology and inflammatory microenvironment: Implications for integrated diagnosis	19
Limbic-predominant age-related TDP-43 encephalopathy (LATE-NC): Co-pathologies and genetic risk factors provide clues about pathogenesis	19
AMPA receptors in Alzheimer disease: Pathological changes and potential therapeutic targets	19
C9orf72 proline-arginine dipeptide repeats disrupt the proteasome and perturb proteolytic activities	18
Phosphorylation of Tau at Threonine 231 in Patients With Multiple System Atrophy and in a Mouse Model	18
Altered expression of human myxovirus resistance protein A in amyotrophic lateral sclerosis	17
The comprehensive morphological and molecular characteristics of lipoastrocytoma: A case report	17
Could conditioned medium be used instead of stem cell transplantation to repair spinal cord injury in animal models? Identifying knowledge gaps	16

Increased efficacy of adipose-derived mesenchymal stem cells transduced with klotho in differentiation and maturation of oligodendrocytes in a mouse model of experimental autoimmune encephalomyelitis	16
Therapeutic potential and challenges of mesenchymal stem cells in neurological disorders: A concise analysis	15
Sevoflurane anesthesia during late gestation induces cognitive disorder in rat offspring via the TLR4/BDNF/TrkB/CREB pathway	15
Contribution of major histocompatibility complex class II immunostaining in distinguishing idiopathic inflammatory myopathy subgroups: A histopathological cohort study	15
Persistent increase of Nogo-A-positive cells and dynamic reduction in oligodendroglia lineage cells in white matter regions following experimental and clinical traumatic brain injury	15
Concurrent Pit-1 and SALL4 staining in primitive component of pituitary blastoma: A case report with clinicopathologic features including Cushing syndrome presentation, germline DICER1 mutation	14
Increased inflammasome protein expression identified in microglia from postmortem brains with schizophrenia	14
Significant contralaterality of temporal-predominant neuroastroglial tauopathy and FTLD-TDP type C presenting with the right temporal variant FTD	14
METTL14/IGF2BP2-mediated m6A modification of PD-L1 promotes proliferation, metastasis, and immune escape in high-grade gliomas	14
Multifocal demyelinating leukoencephalopathy and oligodendroglial lineage cell loss with immune effector cell-associated neurotoxicity syndrome (ICANS) following CD19 CAR T-cell therapy for mantle cel	12
Spatially resolved transcriptomics reveals a unique disease signature and potential biomarkers for chronic traumatic encephalopathy	12
Immune Microenvironment and Lineage Tracing Help to Decipher Rosette-Forming Glioneuronal Tumors: A Multi-Omics Analysis	12
In This Issue	12
METTL3-mediated maturation of miR-192-5p targets ATG7 to prevent Schwann cell autophagy in peripheral nerve injury	12
Exercise-induced acute thrombosis of a cavernous sinus hemangioma	12
In This Issue	12
ZFTA-fused supratentorial ependymoma with a novel fusion partner, DUX4	12
Long noncoding RNA KCNQ1OT1 aggravates cerebral infarction by regulating PTBT1/SIRT1 via miR-16-5p	12
Acquired intradiploic epidermoid cyst: A rare case report with literature review	12
In This Issue	12
Historical review: The golden age of the Golgi method in human neuropathology	11
COVID-19 could worsen cerebral amyloid angiopathy	11
Performance of a condensed protocol to assess limbic-predominant age-related TDP-43 encephalopathy neuropathologic change	11
Neuropathological features of SARS-CoV-2 delta and omicron variants	11
FGFR1 fusions in genomically and epigenetically bona fide glioblastoma, IDH-wildtype	11
Automated deep learning segmentation of neuritic plaques and neurofibrillary tangles in Alzheimer disease brain sections using a proprietary software	11
Histological appearance of topical hemostatic agents and materials in neuropathology	11
Correction to: Polymicrogyria with Dysmorphic Neurons in a Patient with SCN2A Mutation	11
Angiogenic responses are enhanced by recombinant human erythropoietin in a model of periventricular white matter damage of neonatal rats through EPOR-ERK1 signaling	11
Detection of Gram-positive and Gram-negative bacteria in brain abscesses by 16S rRNA in situ hybridization	11
What every neuropathologist needs to know: Update on neuro infectious disease workups and consultation resources	10
Comprehensive identification of FoxO signaling as a promising prognostic and immunotherapeutic biomarker in glioma	10
Merlin immunoreactivity fails to predict neurofibromatosis type 2 mutations in human meningiomas	10
In This Issue	10
Spatial mapping, isolation, and culture of primary human microglia and astrocytes: A systematic review and framework for glial cell-based models	10
Novel YWHAE-NTRK3 fusion in a pediatric glioma	9
Correction to: Mapping the expression of endothelial adhesion receptors for Plasmodium falciparum -infected erythrocytes in fatal cerebral malaria in Mal	9
Persistence of Kii amyotrophic lateral sclerosis after the 2000s and its characteristic aging-related tau astrogliopathy	9
Locus coeruleus TDP-43 pathology in a community-based cohort: Clinical and pathological correlates	9
Perinatal hypoxic-ischemic brain injury: What’s behind the “ribbon effect”?	9
An unusual extra-axial supratentorial presentation of atypical teratoid/rhabdoid tumor in a child	9
Abnormal phosphorylation of protein tyrosine in neurodegenerative diseases	9
Analysis of a large case series of fatal familial insomnia to determine tests with the highest diagnostic value	8
Temporal progression of axonal degeneration in the visual system in experimental autoimmune encephalomyelitis: Insights from high-resolution neuropathology	8
Relationship between promyelocytic leukemia protein nuclear bodies and TAR DNA-binding protein-43 aggregation in spinal anterior horn cells in sporadic amyotrophic lateral sclerosis	8
A rare case of fibromuscular dysplasia involving the cervicocephalic arterial tree highlighting the neuropathological findings	8
Atherogenic-like lesions associated with a progressive chronic vascular degeneration in a rat model of repetitive low-level blast brain injury	8
Differential Vulnerability of Hippocampal Subfields in Primary Age-Related Tauopathy and Chronic Traumatic Encephalopathy	8
Neuropathologic Findings in Galloway-Mowat Syndrome 3 With a Novel OSGEP Variant	8
NOD-like receptor X1 promotes autophagy and inactivates NLR family pyrin domain containing 3 inflammasome signaling by binding autophagy-related gene 5 to alleviate cerebral ischemia/reperfusion-induc	8

NAA10 overexpression dictates distinct epigenetic, genetic, and clinicopathological characteristics in adult gliomas	8
Low clinical sensitivity and unexpectedly high incidence for neuropathologically diagnosed progressive supranuclear palsy	8
Progestin-associated meningiomatosis with unusual schwannoma-like morphology	8
CAPNON: A rare entity with long-term follow-up	8
In This Issue	7
Reactive astrocytes in spinal cord injury: An analysis of heterogeneity based on temporality and spatiality, potential therapies, and limitations	7
Biopsy-proven granulomatous neuromyopathy in a case of Blau syndrome	7
Efficacy of deep brain stimulation for neuronal intranuclear inclusion disease tremor-dominant subtype	7
Donald L. Price, MD 1935–2023	7
In This Issue	6
A novel hypertensive rat model of cerebral small vessel disease: Pathological, cognitive, and neuroimaging implications	6
DNA methylation profiling and histologic analysis of sellar TTF-1-positive papillary epithelial tumor supports a novel CNS entity	6
E-cadherin expression and gene expression profiles in corticotroph pituitary neuroendocrine tumor subtypes	6
Antemortem radiologic and histopathologic presentation of Marchiafava-Bignami disease	6
A Rare Diagnostic Challenge: Choroid Plexus Xanthogranuloma Harboring a Low-Grade Marginal Zone B-Cell Lymphoma	6
Transthyretin immunohistochemistry on muscle and nerve biopsies detects hereditary and wild-type transthyretin amyloidosis with high sensitivity and specificity	6
LncRNA HAGLR promotes the proliferation, migration, and neurotrophic factor production of Schwann cells via miR-204/CDK5R1 after sciatic nerve injury	6
Alzheimer disease-associated tau post-translational modification mimics impact tau propagation and uptake	6
Muscle mitochondrial changes in antisynthetase syndrome and other idiopathic inflammatory myopathies	6
Clinicopathological study of chronic traumatic encephalopathy pathology in a population-based cohort	6
Chronic traumatic encephalopathy and aging-related tau astrogliopathy in community-dwelling older persons with and without moderate-to-severe traumatic brain injury	6
In This Issue	6
Rapid assessment of MGMT promoter methylation status by droplet digital polymerase chain reaction on intraoperative smear preparation: A proof-of-concept	6
C5aR antagonism by PMX205 confers neuroprotection in hypoxic-ischemic brain injury models via anti-inflammatory and anti-apoptotic mechanisms	6
Prevalence of Lewy pathology in essential tremor is twice as high as expected: A plausible explanation for the enhanced risk for Parkinson disease seen in essential tremor cases	6
RagC and Map4K3 deficiency in high-grade gliomas drives proliferation and modulates mTORC1-dependent cellular functions	6
A pleomorphic xanthoastrocytoma highlighting the morphological heterogeneity of this uncommon tumor	6
Chronological Changes in the Expression Pattern of Hippocampal Prion Proteins During Disease Progression in Sporadic Creutzfeldt-Jakob Disease MM1 Subtype	6
Chronic traumatic encephalopathy pathognomonic lesions occurring in isolation adjacent to infiltrative and non-infiltrative white matter lesions	6
Impact of COVID-19 pandemic on neuropathology service: Experience at one Canadian center	5
Cardiotrophin-like cytokine factor 1 regulated by Sry-related HMG-box transcription factor 9 promotes malignant behavior and immune evasion of glioblastoma multiforme	5
In situ seeding assay: A novel technique for direct tissue localization of bioactive tau	5
PAS+/PASD- intracytoplasmic glycogen is not specific for clear cell meningioma	5
In This Issue	5
Authors’ response to: “Alexander disease genetics: Beyond GFAP exon sequencing?”	5
GRN rs5848 variant associates with TDP-43 pathology and cancer in opposite directions	5
Comparative analysis of histopathological parameters, genome-wide copy number alterations, and variants in genes involved in cell cycle regulation in chordomas of the skull base and sacrum	5
Cavernous sinus hemangioma: Histopathological spectrum of 8 cases	5
Unusual immunohistochemical profiles in hemangioblastomas and their relevance in differential diagnosis: A comprehensive study of 112 cases	5
Different cortical and subcortical astroglial responsiveness in rats with acute liver failure	5
Intratumoral heterogeneity of MYC status and methylation subtyping in group 3 medulloblastoma: A case report	5
α-Synuclein distribution in olfactory mucosa and skin nerves in Parkinson disease associated with an EIF4G1 gene mutation	5
Intracellular calcium dysregulation in heart and brain diseases: Insights from induced pluripotent stem cell studies	5
Skin Biopsy as a Novel Diagnostic Aid in Immune-Mediated Neuropathies	5
Cortical variant multiple sclerosis presenting clinically as Lewy body dementia	5
In This Issue	5
Neuropathology of classic myotonic dystrophy type 1 is characterized by both early initiation of primary age-related tauopathy of the hippocampus and unique 3-repeat tauopathy of the brainstem	5
Prostate-Specific Membrane Antigen Expression in Meningioma: A Promising Theranostic Target	5
Hippocampal synaptic alterations associated with tau pathology in primary age-related tauopathy	5
A comparison of CDKN2A status in gliomas using different techniques: The loss of p16 as a surrogate marker	5
β-Amyloid species production and tau phosphorylation in iPSC-neurons with reference to neuropathologically characterized matched donor brains	5
The association between virus-induced spinal cord pathology and the genetic background of the host	5
Comparison of multiple quantitative strategies for neuropathologic image analyses	5
Clinical, Pathological, and Molecular Characteristics of Diffuse Spinal Cord Gliomas	4
Alteration of Vesicle-Associated Membrane Protein-Binding Protein B in α-Synuclein Aggregates in Lewy Body Disease	4
Comparing Gallyas and AT8 staining for quantification of tau pathology in subregions of the human hippocampus	4
EGFR Exon 20 Insertion in Bithalamic and Unithalamic Glioma: A Report of 2 Cases and Literature Review	4
Digital Histological Study of Neocortical Grey and White Matter Tau Burden Across Tauopathies	4
In This Issue	4
In This Issue	4
Downregulating Cdk5 reverses hippocampal neuron ferroptosis by regulating the AMP-activated protein kinase pathway and “M1” polarized microglia	4
Gliomas with succinate dehydrogenase deficiency: A case series and brief review of the literature of oncometabolite-driven gliomagenesis	4
Mapping the expression of endothelial adhesion receptors for Plasmodium falciparum -infected erythrocytes in fatal cerebral malaria in Malawian children	4
Leucine-rich pentatricopeptide repeat-containing protein silencing transcriptionally regulated by GATA-binding protein 3 has an anti-glioma effect by regulating glycolysis and ferroptosis by mediating	4
Comprehensive analysis of distinct circadian clock subtypes of adult diffuse glioma and their associations with clinicopathological, genetic, and epigenetic profiles	4
Potential of the pharmacological inhibition of CCL2-CCR2 axis via targeting FROUNT to prevent the initiation and the progression of intracranial aneurysms in rats	4
In severe ADNC, hippocampi with comorbid LATE-NC and hippocampal sclerosis have substantially more astrocytosis than those with LATE-NC or hippocampal sclerosis alone	4
Expanding the differential diagnosis for dural-based spindle cell neoplasms: A report of a rare GLI1 -altered mesenchymal tumor of the CNS	4
A custom next-generation sequencing panel for 1p/19q codeletion and mutational analysis in gliomas	4
Preanalytic variable effects on segmentation and quantification machine learning algorithms for amyloid-β analyses on digitized human brain slides	4
Molecular characterization of benign intracranial glioependymal and arachnoid cysts suggest heterogeneous mechanisms of action	4
In This Issue	4
Ependymal-like tumor with SMARCA2::PLAGL1 fusion: A novel molecular driver in neuroepithelial tumors with PLAGL1	4
Identification of diagnostic biomarkers for relapsing-remitting multiple sclerosis in plasma by mass spectrometry-based proteomics	4
In This Issue	4
Integrating molecular analyses with the 2021 WHO classification of adult pilocytic astrocytomas	4
Comorbidities in early-onset sporadic versus presenilin-1 mutation-associated Alzheimer disease dementia: Evidence for dependency on Alzheimer disease neuropathological changes	4
In This Issue	4
Cytoplasmic expression of trans-active response DNA-binding protein-43 in aged mice display hippocampal sclerosis-like degeneration and neuronal loss with reduced lifespan	4
Altered 5-HT2A/C receptor binding in the medulla oblongata in the sudden infant death syndrome (SIDS): Part II. Age-associated alterations in serotonin receptor binding profiles within medullary nucle	4