OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Neuropathology and Experimental Neurology is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
The Second NINDS/NIBIB Consensus Meeting to Define Neuropathological Criteria for the Diagnosis of Chronic Traumatic Encephalopathy	91
Prognostic Value of Histopathological Features and Loss of H3K27me3 Immunolabeling in Anaplastic Meningioma: A Multicenter Retrospective Study	39
Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy	35
Molecular Correlates of Long Survival in IDH-Wildtype Glioblastoma Cohorts	31
Fundamentals of the Development of Connectivity in the Human Fetal Brain in Late Gestation: From 24 Weeks Gestational Age to Term	28
Advances in Deep Neuropathological Phenotyping of Alzheimer Disease: Past, Present, and Future	25
What Every Neuropathologist Needs to Know: The Muscle Biopsy	25
Chronic Traumatic Encephalopathy (CTE)-Type Neuropathology in a Young Victim of Domestic Abuse	24
Risk of Transmissibility From Neurodegenerative Disease-Associated Proteins: Experimental Knowns and Unknowns	23
LATE Neuropathologic Changes with Little or No Alzheimer Disease is Common and is Associated with Cognitive Impairment but Not Frontotemporal Dementia	23
Multiple Sclerosis: Microglia, Monocytes, and Macrophage-Mediated Demyelination	22
Myelin Pathology Beyond White Matter in Tuberous Sclerosis Complex (TSC) Cortical Tubers	22
SARS-CoV-2 Brain Regional Detection, Histopathology, Gene Expression, and Immunomodulatory Changes in Decedents with COVID-19	22
Deep Learning-Based Image Classification in Differentiating Tufted Astrocytes, Astrocytic Plaques, and Neuritic Plaques	21
Hemodynamic Force as a Potential Regulator of Inflammation-Mediated Focal Growth of Saccular Aneurysms in a Rat Model	18
Periostin Is Expressed by Pericytes and Is Crucial for Angiogenesis in Glioma	18
Detailed Clinical and Histopathological Description of 8 Cases of Molecularly Defined CNS Neuroblastomas	18
Vascular Lesions, APOE ε4, and Tau Pathology in Alzheimer Disease	17
Asymmetry of Hippocampal Tau Pathology in Primary Age-Related Tauopathy and Alzheimer Disease	17
Rat and Mouse Brain Tumor Models for Experimental Neuro-Oncology Research	15
Expression of GFAP and Tau Following Blast Exposure in the Cerebral Cortex of Ferrets	15
Novel Glutamine Antagonist JHU395 Suppresses MYC-Driven Medulloblastoma Growth and Induces Apoptosis	14
The Role of Liquid Biopsies in Pediatric Brain Tumors	14
Muscle Biopsy Findings in a Case of SARS-CoV-2-Associated Muscle Injury	14
Glioma-Derived TSP2 Promotes Excitatory Synapse Formation and Results in Hyperexcitability in the Peritumoral Cortex of Glioma	14

Overcoming the Odds: Toward a Molecular Profile of Long-Term Survival in Glioblastoma	14
Activation of CaMKII and GluR1 by the PSD-95-GluN2B Coupling-Dependent Phosphorylation of GluN2B in the Spinal Cord in a Rat Model of Type-2 Diabetic Neuropathic Pain	13
Emergent Viral Infections of the CNS	13
Ketamine Regulates the Autophagy Flux and Polarization of Microglia through the HMGB1-RAGE Axis and Exerts Antidepressant Effects in Mice	13
Molecular Signatures of Chromosomal Instability Correlate With Copy Number Variation Patterns and Patient Outcome in IDH-Mutant and IDH-Wildtype Astrocytomas	13
Expression and Prognostic Value of the Immune Checkpoints Galectin-9 and PD-L1 in Glioblastomas	13
Polymorphous Low-Grade Neuroepithelial Tumor of the Young (PLNTY): Molecular Profiling Confirms Frequent MAPK Pathway Activation	13
Expression Profiling of Primary and Recurrent Glioblastomas Reveals a Reduced Level of Pentraxin 3 in Recurrent Glioblastomas	13
Membrane Structures Between Craniopharyngioma and the Third Ventricle Floor Based on the QST Classification and Its Significance: A Pathological Study	13
Downregulation of Long Noncoding RNA TUG1 Attenuates MTDH-Mediated Inflammatory Damage via Targeting miR-29b-1-5p After Spinal Cord Ischemia Reperfusion	13
Inflammatory Pathways Are Impaired in Alzheimer Disease and Differentially Associated With Apolipoprotein E Status	12
Differences in Symptomatic Presentation and Cognitive Performance Among Participants With LATE-NC Compared to FTLD-TDP	12
Tau Pathology in Chronic Traumatic Encephalopathy is Primarily Neuronal	12
Practical Considerations in the Diagnosis of Mild Chronic Traumatic Encephalopathy and Distinction From Age-Related Tau Astrogliopathy	12
Dysregulation of the MMP/TIMP Proteolytic System in Subependymal Giant Cell Astrocytomas in Patients With Tuberous Sclerosis Complex: Modulation of MMP by MicroRNA-320d In Vitro	12
The Effect of Curcumin on Idiopathic Parkinson Disease: A Clinical and Skin Biopsy Study	12
TDP-43 Vasculopathy in the Spinal Cord in Sporadic Amyotrophic Lateral Sclerosis (sALS) and Frontal Cortex in sALS/FTLD-TDP	12
Neuropathological findings in COVID-19: an autopsy cohort	12
Chronic Treatment With Hydrogen Sulfide Donor GYY4137 Mitigates Microglial and Astrocyte Activation in the Spinal Cord of Streptozotocin-Induced Diabetic Rats	11
Correlation of MTAP Immunohistochemistry With CDKN2A Status Assessed by Fluorescence In Situ Hybridization and Clinicopathological Features in CNS WHO Grade 2 and 3 Meningiomas: A Single Center Cohort	11
PTEN Blocking Stimulates Corticospinal and Raphespinal Axonal Regeneration and Promotes Functional Recovery After Spinal Cord Injury	11
The Cryo-EM Effect: Structural Biology of Neurodegenerative Disease Aggregates	11
Molecular Characterization of “True” Low-Grade IDH-Wildtype Astrocytomas	11
Cognitive resistance to and resilience against multiple comorbid neurodegenerative pathologies and the impact of APOE status	11
Apolipoprotein E ε4 Mediates Myelin Breakdown by Targeting Oligodendrocytes in Sporadic Alzheimer Disease	10
The Alzheimer Disease-Causing Presenilin-1 L435F Mutation Causes Increased Production of Soluble Aβ43 Species in Patient-Derived iPSC-Neurons, Closely Mimicking Matched Patient Brain Tissue	10
Tau Isoform Profile in Essential Tremor Diverges From Other Tauopathies	10
Bone Marrow-Derived Mesenchymal Stem Cell-Derived Exosomes Containing Gli1 Alleviate Microglial Activation and Neuronal Apoptosis In Vitro and in a Mouse Parkinson Disease Model by Direct Inhibition o	10
Aggressive Medulloblastoma-Derived Exosomal miRNAs Promote In Vitro Invasion and Migration of Tumor Cells Via Ras/MAPK Pathway	10
COVID-19 Patients With CNS Complications and Neuropathologic Features of Acute Disseminated Encephalomyelitis and Acute Hemorrhagic Leukoencephalopathy	10
The Multipotential of Leucine-Rich α-2 Glycoprotein 1 as a Clinicopathological Biomarker of Glioblastoma	9
Injection of Cerium Oxide Nanoparticles to Treat Spinal Cord Injury in Rats	9
Symptomatic Profile and Cognitive Performance in Autopsy-Confirmed Limbic-Predominant Age-Related TDP-43 Encephalopathy With Comorbid Alzheimer Disease	9
Traumatic Brain Injury-Related Optic Nerve Damage	9
A Heterozygous Mutation in the Filamin C Gene Causes an Unusual Nemaline Myopathy With Ring Fibers	9
A Fatal Case of Powassan Virus Encephalitis	9
Alterations in the RB Pathway With Inactivation of RB1 Characterize Glioblastomas With a Primitive Neuronal Component	9
Exploring DNA Methylation for Prognosis and Analyzing the Tumor Microenvironment in Pleomorphic Xanthoastrocytoma	9
Spatially Resolved and Quantitative Analysis of the Immunological Landscape in Human Meningiomas	9
Distribution of TDP-43 Pathology in Hippocampal Synaptic Relays Suggests Transsynaptic Propagation in Frontotemporal Lobar Degeneration	9
Repetitive Traumatic Brain Injury Is Associated With TDP-43 Alterations, Neurodegeneration, and Glial Activation in Mice	9
Broadening the Age of Incidence of Intracranial Angiomatoid Fibrous Histiocytoma With EWSR1-CREM Fusion: A Case Report	8
Induction of CCN1 in Growing Saccular Aneurysms: A Potential Marker Predicting Unstable Lesions	8
Pathology Features of Immune and Inflammatory Myopathies, Including a Polymyositis Pattern, Relate Strongly to Serum Autoantibodies	8
Nuclear IMPDH Filaments in Human Gliomas	8
Brain Cell Senescence: A New Therapeutic Target for the Acute Treatment of Ischemic Stroke	8
Reduced Levels of Intestinal Neuropeptides and Neurotrophins in Neurotoxin-Induced Parkinson Disease Mouse Models	8
High-Throughput Digital Image Analysis Reveals Distinct Patterns of Dystrophin Expression in Dystrophinopathy Patients	8
Knockout of Transient Receptor Potential Melastatin 4 Channel Mitigates Cerebral Edema and Neuronal Injury After Status Epilepticus in Mice	8
Neuropathological features of SARS-CoV-2 delta and omicron variants	8

MGMT Promoter Methylation Status Is Not Related to Histological or Radiological Features in IDH Wild-type Glioblastomas	8
Aberrant Expression of Nodal and Paranodal Molecules in Neuropathy Associated With IgM Monoclonal Gammopathy With Anti-Myelin-Associated Glycoprotein Antibodies	8
Clinicopathological Staging of Dynamics of Neurodegeneration and Neuronal Loss in Alzheimer Disease	8
Authors’ Response	8
Medulloblastoma in Adults: Cytogenetic Phenotypes Identify Prognostic Subgroups	8
LncRNA BC083743 Promotes the Proliferation of Schwann Cells and Axon Regeneration Through miR-103-3p/BDNF After Sciatic Nerve Crush	8
NOTCH2NLC CGG Repeats Are Not Expanded and Skin Biopsy Was Negative in an Infantile Patient With Neuronal Intranuclear Inclusion Disease	8
Calcitriol Pretreatment Attenuates Glutamate Neurotoxicity by Regulating NMDAR and CYP46A1 Gene Expression in Rats Subjected to Transient Middle Cerebral Artery Occlusion	7
Entrapped Megakaryocytes in the Microvasculature of Brain Tissues are not Specific to COVID-19 but can be Seen Across a Spectrum of Acute Lung Injuries	7
Pontine Arteriolosclerosis and Locus Coeruleus Oxidative Stress Differentiate Resilience from Mild Cognitive Impairment in a Clinical Pathologic Cohort	7
Vascular injury is associated with repetitive head impacts and tau pathology in chronic traumatic encephalopathy	7
Fast Progression in Amyotrophic Lateral Sclerosis Is Associated With Greater TDP-43 Burden in Spinal Cord	7
Advanced Glycation End Product Formation in Human Cerebral Cortex Increases With Alzheimer-Type Neuropathologic Changes but Is Not Independently Associated With Dementia in a Population-Derived Aging	7
Molecular Alterations in Pediatric Low-Grade Gliomas That Led to Death	7
Rosette-Forming Glioneuronal Tumor in the Pineal Region: A Series of 6 Cases and Literature Review	7
Multifocal Necrotizing Leukoencephalopathy With Preferential Microglia Toxicity in a Patient Treated With Chimeric Antigen Receptor T-Cells and Review of the Literature	7
PCBP2 Is Downregulated in Degenerating Neurons and Rarely Observed in TDP-43-Positive Inclusions in Sporadic Amyotrophic Lateral Sclerosis	7
Aβ Deposits in the Neocortex of Adult and Infant Hypoxic Brains, Including in Cases of COVID-19	7
A Longitudinal Skin Biopsy Study of Phosphorylated Alpha-Synuclein in a Patient With Parkinson Disease and Orthostatic Hypotension	7
Widespread Mislocalization of FUS Is Associated With Mitochondrial Abnormalities in Skeletal Muscle in Amyotrophic Lateral Sclerosis With FUS Mutations	7
Electroacupuncture Alleviates Neuroinflammation and Motor Dysfunction by Regulating Intestinal Barrier Function in a Mouse Model of Parkinson Disease	7
Somatic Focal Copy Number Gains of Noncoding Regions of Receptor Tyrosine Kinase Genes in Treatment-Resistant Epilepsy	7
Inhibition of circ_0004381 improves cognitive function via miR-647/PSEN1 axis in an Alzheimer disease mouse model	6
Distinct Brain Proteomic Signatures in Cerebral Small Vessel Disease Rat Models of Hypertension and Cerebral Amyloid Angiopathy	6
PRKCA D463H Mutation in Chordoid Glioma of the Third Ventricle: A Cohort of 16 Cases, Including Two Cases Harboring BRAFV600E Mutation	6
Characterizing Lewy Pathology in 231 Essential Tremor Brains From the Essential Tremor Centralized Brain Repository	6
OLIG2 Immunolabeling of Mesenchymal Chondrosarcoma: Report of 14 Cases	6
Differential Vulnerability of Hippocampal Subfields in Primary Age-Related Tauopathy and Chronic Traumatic Encephalopathy	6
Localized Hypertrophic Neuropathy as a Neoplastic Manifestation of KRAS-Mediated RASopathy	6
Insoluble Tau From Human FTDP-17 Cases Exhibit Unique Transmission Properties In Vivo	6
American Association of Neuropathologists, Inc. Abstracts of the 98th Annual Meeting June 9-12, 2022 Bonita Springs, Florida	6
Infiltrating Hematogenous Macrophages Aggregate Around β-Amyloid Plaques in an Age- and Sex-Dependent Manner in a Mouse Model of Alzheimer Disease	6
Microglial heterogeneity in amyotrophic lateral sclerosis	6
CD33 and SIGLECL1 Immunoglobulin Superfamily Involved in Dementia	6
Von Economo Neuron Pathology in Familial Dysautonomia: Quantitative Assessment and Possible Implications	6
Novel RAF Fusions in Pediatric Low-Grade Gliomas Demonstrate MAPK Pathway Activation	6
Medial Gap: A Structural Factor at the Arterial Bifurcation Aggravating Hemodynamic Insult	6
Systematic Classification of Spina Bifida	6
Chronic Traumatic Encephalopathy in a Routine Neuropathology Service in Australia	6
Cobblestone Malformation in LAMA2 Congenital Muscular Dystrophy (MDC1A)	6
MicroRNA-155-5p Targets SKP2, Activates IKKβ, Increases Aβ Aggregation, and Aggravates a Mouse Alzheimer Disease Model	6
Expression of Mutant Ubiquitin and Proteostasis Impairment in Kii Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex Brains	6
Neuromuscular Choristoma: Report of Five Cases With CTNNB1 Sequencing	6
Is Next-Generation Sequencing Alone Sufficient to Reliably Diagnose Gliomas?	6
Serum Amyloid A Is Present in Human Saccular Intracranial Aneurysm Walls and Associates With Aneurysm Rupture	5
GLI3 Is Associated With Neuronal Differentiation in SHH-Activated and WNT-Activated Medulloblastoma	5
Genetic and Pathological Characteristic Patterns of a Family With Neuronal Intranuclear Inclusion Disease	5
Accumulation of Nonfibrillar TDP-43 in the Rough Endoplasmic Reticulum Is the Early-Stage Pathology in Amyotrophic Lateral Sclerosis	5
Cytoplasmic Mislocalization of RNA Polymerase II Subunit RPB1 in Alzheimer Disease Is Linked to Pathologic Tau	5
Diagnosis and Clinical Development of Sporadic Inclusion Body Myositis and Polymyositis With Mitochondrial Pathology: A Single-Center Retrospective Analysis	5
American Association of Neuropathologists, Inc. Abstracts of the 97th Annual Meeting June 10-13, 2021 St. Louis, Missouri	5
Targeted Next-Generation Sequencing Reveals Divergent Clonal Evolution in Components of Composite Pleomorphic Xanthoastrocytoma-Ganglioglioma	5
Familial Pediatric Clear Cell Meningioma With Germline SMARCE1 Mutation in the United States	5
Hippocampal Sclerosis in Frontotemporal Dementia: When Vascular Pathology Meets Neurodegeneration	5
Phenotypic Spectrum of α-Dystroglycanopathies Associated With the c.919T>a Variant in the FKRP Gene in Humans and Mice	5
Periventricular White Matter Alterations From Explosive Blast in a Large Animal Model: Mild Traumatic Brain Injury or “Subconcussive” Injury?	5
NTRK Fusions Can Co-Occur With H3K27M Mutations and May Define Druggable Subclones Within Diffuse Midline Gliomas	5
Mechanisms of Cerebral Microbleeds	5
Elevated Oxidative Stress and DNA Damage in Cortical Neurons of Chemotherapy Patients	5
Azetidine-2-Carboxylic Acid-Induced Oligodendrogliopathy: Relevance to the Pathogenesis of Multiple Sclerosis	5
Tumor-Infiltrating Lymphocytes Are Enriched in Nonhypoxic Glioblastoma Niches	5
Alterations in the Expression of the Genes Responsible for the Synthesis of Heparan Sulfate in Brains With Alzheimer Disease	5
Expanding the Phenotype of Frontotemporal Lobar Degeneration With FUS-Positive Pathology (FTLD-FUS)	5
Immunohistochemical Phenotype of T Cells Invading Muscle in Inclusion Body Myositis	5
Preanalytic variable effects on segmentation and quantification machine learning algorithms for amyloid-β analyses on digitized human brain slides	5
A History of Senile Plaques: From Alzheimer to Amyloid Imaging	5
Preferentially Expressed Antigen in Melanoma (PRAME) Expression in Malignant, but Not Benign, Peripheral Nerve Sheath Tumors	5
Combining Hypothermia and Oleuropein Subacutely Protects Subcortical White Matter in a Swine Model of Neonatal Hypoxic-Ischemic Encephalopathy	5
Histological Findings After Aortic Cross-Clamping in Preclinical Animal Models	5
Primary Progressive Aphasia has a Unique Signature Distinct from Dementia of the Alzheimer’s Type and Behavioral Variant Frontotemporal Dementia Regardless of Pathology	5