OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Neuropathology and Experimental Neurology is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
What every neuropathologist needs to know: condensed protocol work-up for clinical dementia syndromes	122
Progressive Hereditary Transthyretin-Related Amyloidosis (ATTRv) Aggravated by ATTR Wild-Type and Complement Activation	37
Prognostic Relevance of Transforming Growth Factor-β Receptor Expression and Signaling in Glioblastoma, Isocitrate Dehydrogenase-Wildtype	33
Vasculocentric Axonal NfH in Small Vessel Disease	31
A Neuropathological Study of Diffuse Vascular Injury in Fatal Motor Vehicle Collisions	27
A novel grading system combining histological grade and CDKN2A homozygous and hemizygous deletion to predict prognosis in IDH-mutant astrocytoma	27
Clinicopathologic features of a novel star-shaped transactive response DNA-binding protein 43 (TDP-43) pathology in the oldest old	26
Chronic traumatic encephalopathy pathognomonic lesions occurring in isolation adjacent to infiltrative and non-infiltrative white matter lesions	23
Primary CNS histiocytic sarcoma: Two case reports highlighting a novel MIGA2::BRAF gene fusion and genome-wide DNA methylation profiling results	21
Revealing the potential role of hsa-miR-663a in modulating the PI3K-Akt signaling pathway via miRNA microarray in spinal muscular atrophy patient fibroblast-derived iPSCs	20
Tau Pathology in Chronic Traumatic Encephalopathy is Primarily Neuronal	19
Molecular Alterations in Pediatric Low-Grade Gliomas That Led to Death	17
Maturation of metastases in peripheral neuroblastic tumors (neuroblastoma) of children	17
Chronic Traumatic Encephalopathy in a Routine Neuropathology Service in Australia	16
ANKRD22 promotes glioma proliferation, migration, invasion, and epithelial-mesenchymal transition by upregulating E2F1-mediated MELK expression	16
Entrapped Megakaryocytes in the Microvasculature of Brain Tissues are not Specific to COVID-19 but can be Seen Across a Spectrum of Acute Lung Injuries	16
Diagnostic yield of postmortem brain examination following premortem brain biopsy for neoplastic and nonneoplastic disease	15
Focal Chronic Meningitis With Lymphoid Follicle-Like Structures Associated With Cocaine-Induced Midline Destructive Lesion: A Case Report	14
Survival in sporadic ALS is associated with lower p62 burden in the spinal cord	14
What Every Neuropathologist Needs to Know: Practical Aspects and Pitfalls in Molecular Diagnosis of Brain Tumors	14
A Novel, Heterozygous BSCL2 Variant in Association With Early-Onset Epileptic Encephalopathy	14
Vitamin D alleviates neuronal injury in cerebral ischemia-reperfusion via enhancing the Nrf2/HO-1 antioxidant pathway to counteract NLRP3-mediated pyroptosis	14
Dysregulated Protein Phosphorylation in a Mouse Model of FTLD-Tau	14
Azetidine-2-Carboxylic Acid-Induced Oligodendrogliopathy: Relevance to the Pathogenesis of Multiple Sclerosis	14
Microglial heterogeneity in amyotrophic lateral sclerosis	13

Diffuse hemispheric glioma with H3-3B G34R mutation: Expanding the spectrum of histone H3 genes in diffuse hemispheric glioma, H3 G34-mutant	13
Pathologic Findings Associated With a Case of Acute Flaccid Myelitis	12
Neural Injury and Repair in a Novel Neonatal Mouse Model of Listeria Monocytogenes Meningoencephalitis	12
In This Issue	12
Application of Genome-Wide DNA Methylation Analysis to Differentiate a Case of Radiation-Induced Glioblastoma From Late-Relapsed Medulloblastoma	12
Appreciation of Reviewers	11
Histological Findings After Aortic Cross-Clamping in Preclinical Animal Models	11
LncRNA HAGLR promotes the proliferation, migration, and neurotrophic factor production of Schwann cells via miR-204/CDK5R1 after sciatic nerve injury	11
A Rare Diagnostic Challenge: Choroid Plexus Xanthogranuloma Harboring a Low-Grade Marginal Zone B-Cell Lymphoma	11
Tissue clearing to examine glioma complexity in 3 dimensions	10
Extensive Postnatal Brainstem Calcification in a Premature Infant	10
Stirling Carpenter, MD February 27, 1929–February 19, 2021	10
An unusual case of metastatic diffuse midline glioma in an adult	10
Glioblastoma, IDH-Wildtype Harboring a KIAA1549::BRAF Fusion: Report of a Case With Comprehensive Molecular Profiling	10
In This Issue	10
DNA methylation profile of human dura and leptomeninges	10
Extradural Chordoma of the Thoracic Spine without Bony Involvement: A Rare Presentation and Case Report	10
A pleomorphic xanthoastrocytoma highlighting the morphological heterogeneity of this uncommon tumor	9
The Neuropathology of 1p36 Deletion Syndrome: An Autopsy Case Series	9
John Q. Trojanowski, MD, PhDDecember 17, 1946–February 8, 2022	9
Translocator protein (TSPO) expression in neoplastic cells and tumor-associated macrophages in meningiomas	9
Dexmedetomidine Inhibits NF-κB-Transcriptional Activity in Neurons Undergoing Ischemia-Reperfusion by Regulating O-GlcNAcylation of SNW1	9
Autopsy findings in a 6-month-old infant with rhabdoid tumor predisposition syndrome 1: Case report with literature review	9
Dural Marginal Zone Lymphoma With Extensive Crystal Storing Histiocytosis: Spotting the Zebra Among the Horses	9
Heterogenous driving genetic events contribute to the dissemination of choroid plexus papilloma	8
Supratentorial ependymoma, ZFTA fusion-positive, with extensive mesenchymal differentiation	8
Multiple Sclerosis: Microglia, Monocytes, and Macrophage-Mediated Demyelination	8
Breviscapine ameliorates autophagy by activating the JAK2/STAT5/BCL2 pathway in a transient cerebral ischemia rat model	8
Pronounced decline of absolute cell numbers in the brain of a newborn with congenital syphilis	8
Multidimensional analysis of matched primary and recurrent glioblastoma identifies contributors to tumor recurrence influencing time to relapse	8
Targeted Next-Generation Sequencing Reveals Divergent Clonal Evolution in Components of Composite Pleomorphic Xanthoastrocytoma-Ganglioglioma	8
The Effect of Curcumin on Idiopathic Parkinson Disease: A Clinical and Skin Biopsy Study	8
Differentiating pathologic tau in chronic traumatic encephalopathy (CTE) from other tauopathies: A potential antibody panel assessment	8
SMP30 alleviates cerebral ischemia/reperfusion-induced neuronal injury by inhibiting HDAC4/PSD-95 to preserve mitochondrial function	8
In This Issue	8
Charcot Bouchard aneurysm: Case report and critical literature review	7
Bone Marrow Stem Cell-Exo-Derived TSG-6 Attenuates 1-Methyl-4-Phenylpyridinium+-Induced Neurotoxicity via the STAT3/miR-7/NEDD4/LRRK2 Axis	7
Traumatic Brain Injury-Related Optic Nerve Damage	7
Dynamic changes in key factors of the blood-brain barrier in early diabetic mice	7
Lipid and protein imbalances in muscle of a FAR1-patient with a heterozygous de novo variant	7
AMPA receptors in Alzheimer disease: Pathological changes and potential therapeutic targets	7
LATE Neuropathologic Changes with Little or No Alzheimer Disease is Common and is Associated with Cognitive Impairment but Not Frontotemporal Dementia	7
The GPER1 agonist G1 reduces brain injury and improves the qEEG and behavioral outcome of experimental ischemic stroke	7
MicroRNA-155-5p Targets SKP2, Activates IKKβ, Increases Aβ Aggregation, and Aggravates a Mouse Alzheimer Disease Model	7
Dual white matter pathology in fetal holoprosencephaly featuring concurrent malformative and destructive features: A case series	7
Neuroprotection of Heme Oxygenase-2 in Mice AfterIntracerebral Hemorrhage	7
Ferritin is closely associated with microglia in amyotrophic lateral sclerosis	7
Omega-3 polyunsaturated fatty acids alleviate endoplasmic reticulum stress-induced neuroinflammation by protecting against traumatic spinal cord injury through the histone deacetylase 3/ peroxisome pr	7
First-time identification of a KIF5B-NTRK2 fusion in extraventricular neurocytoma	7
Reliability assessment of methylthioadenosine phosphorylase immunohistochemistry as a surrogate biomarker for CDKN2A homozygous deletion in adult-type IDH-mutant diffuse gliomas	7

Postmortem 7T MRI for guided histopathology and evaluation of cerebrovascular disease	7
Evolving driver mutations in adult-onset SHH-medulloblastoma originated from radiological cerebellar abnormality	7
Accumulation of TMEM106B C-terminal fragments in Niemann-Pick type C disease	7
Skin biopsy detection of phosphorylated α-synuclein to identify patients with synucleinopathies	7
NFYB increases chemosensitivity in glioblastoma by promoting HDAC5-mediated transcriptional inhibition of SHMT2	7
Limbic-predominant age-related TDP-43 encephalopathy (LATE-NC): Co-pathologies and genetic risk factors provide clues about pathogenesis	7
METTL3 confers protection against mitochondrial dysfunction and cognitive impairment in an Alzheimer disease mouse model by upregulating Mfn2 via N6-methyladenosine modification	6
The Cryo-EM Effect: Structural Biology of Neurodegenerative Disease Proteostasis Factors	6
In This Issue	6
Leptomeningeal metastases and dural spread in adult high-grade astrocytomas	6
Characterizing Lewy Pathology in 231 Essential Tremor Brains From the Essential Tremor Centralized Brain Repository	6
Cognitive symptoms progress with limbic-predominant age-related TDP-43 encephalopathy stage and co-occurrence with Alzheimer disease	6
miR-15b-5p transcription mediated by CREB1 protects against inflammation and apoptosis in Parkinson disease models by inhibiting AXIN2 and activating Wnt/β-catenin	6
Comparing loss of p16 and MTAP expression in detecting CDKN2A homozygous deletion in pleomorphic xanthoastrocytoma	6
Transdifferentiation of metastatic melanoma into cerebellar angiosarcoma	6
Polymorphous Low-Grade Neuroepithelial Tumor of the Young (PLNTY): Molecular Profiling Confirms Frequent MAPK Pathway Activation	6
Fundamentals of the Development of Connectivity in the Human Fetal Brain in Late Gestation: From 24 Weeks Gestational Age to Term	6
Postmortem neuropathology in early Huntington disease	6
Pediatric Gliomas Presenting with Gliomatosis-Like Spread, Lack of Contrast Enhancement, EGFR Mutation, and TERT Promoter Variants	6
Analyses of DNA Methylation Profiling in the Diagnosis of Intramedullary Astrocytomas	6
Secondary IDH-mutant gliosarcoma in a patient with prior IDH-mutant grade 2 astrocytoma	5
Microglia subtypes in acute, subacute, and chronic multiple sclerosis	5
YTHDF2-regulated matrilin-3 mitigates post-reperfusion hemorrhagic transformation in ischemic stroke via the PI3K/AKT pathway	5
Rat and Mouse Brain Tumor Models for Experimental Neuro-Oncology Research	5
Sevoflurane anesthesia during late gestation induces cognitive disorder in rat offspring via the TLR4/BDNF/TrkB/CREB pathway	5
Effects of STN/SNr deep brain stimulation in a case of progressive supranuclear palsy with a Parkinson disease phenotype	5
PDGFB:APOBEC3C fusion in congenital diffuse high-grade glioma of the brainstem	5
Novel Glutamine Antagonist JHU395 Suppresses MYC-Driven Medulloblastoma Growth and Induces Apoptosis	5
Alterations in the RB Pathway With Inactivation of RB1 Characterize Glioblastomas With a Primitive Neuronal Component	5
Phosphorylation of Tau at Threonine 231 in Patients With Multiple System Atrophy and in a Mouse Model	5
Could conditioned medium be used instead of stem cell transplantation to repair spinal cord injury in animal models? Identifying knowledge gaps	5
Prostate-Specific Membrane Antigen Expression in Meningioma: A Promising Theranostic Target	5
Bioengineered Models to Study Microenvironmental Regulation of Glioblastoma Metabolism	5
Distinct Brain Proteomic Signatures in Cerebral Small Vessel Disease Rat Models of Hypertension and Cerebral Amyloid Angiopathy	5
An Unusual Presentation of CLN3-Associated Batten Disease With Classic Histopathologic and Ultrastructural Findings	5
Olfactory Bulb Amyloid-β Correlates With Brain Thal Amyloid Phase and Severity of Cognitive Impairment	5
Ultrastructural endothelial cell alterations in methanol poisoning with bilateral putaminal hemorrhages: An autopsy case report	5
Hippocampal synaptic alterations associated with tau pathology in primary age-related tauopathy	5
The frequency and distribution of TDP-43 pathology in argyrophilic grain disease	5
Chronological Changes in the Expression Pattern of Hippocampal Prion Proteins During Disease Progression in Sporadic Creutzfeldt-Jakob Disease MM1 Subtype	4
D-2-hydroxyglutarate regulates human brain vascular endothelial cell proliferation and barrier function	4
LEF-1 immunohistochemistry, a better diagnostic biomarker than β-catenin for medulloblastoma, WNT-activated subtyping	4
C9orf72 proline-arginine dipeptide repeats disrupt the proteasome and perturb proteolytic activities	4
Authors’ reply to: “Neuropathologic findings in COVID-19 patients should be correlated with clinical neurologic abnormalities”	4
Neuropathology of classic myotonic dystrophy type 1 is characterized by both early initiation of primary age-related tauopathy of the hippocampus and unique 3-repeat tauopathy of the brainstem	4
Neuroprotection by Trans-Resveratrol in Rats With Intracerebral Hemorrhage: Insights into the Role of Adenosine A1 Receptors	4
In This Issue	4
The AANP, JNEN, and Me	4
A case of dedifferentiated meningeal solitary fibrous tumor	4
In This Issue	4
In This Issue	4
Meritorious Contributions to Neuropathology	4
Whole gain of chromosome 19, not co-gain of chromosomes 19 and 20, characterizes a class of glioblastomas with more favorable outcomes	4
American Association of Neuropathologists, Inc. Abstracts of the 99th Annual Meeting June 8–11, 2023 Monterey, California	4
Correction to: Basal Recess in Third Ventricle Tumors: A Pathological Feature Defining a Clinical-Topographical Subpopulation of Papillary Craniopharyngiomas	4
Neuropathology and Ophthalmological Pathology of Fatal Central Nervous System Injuries in Young Children: Forensic Neuropathology of Deaths of Children Under Age 2, 2008–2016, in Central Missouri	4
American Association of Neuropathologists, Inc. Abstracts of the 98th Annual Meeting June 9-12, 2022 Bonita Springs, Florida	4
In This Issue	3
Lipohyalinosis and Fibrinoid: Consistent and Important Failure to Understand These Are Synonyms	3
Deposition of Phosphorylated α-Synuclein and Activation of GSK-3β and PP2A in the PS19 Mouse Model of Tauopathy	3
The comprehensive morphological and molecular characteristics of lipoastrocytoma: A case report	3
Altered expression of human myxovirus resistance protein A in amyotrophic lateral sclerosis	3
American Association of Neuropathologists, Inc. Abstracts of the 97th Annual Meeting June 10-13, 2021 St. Louis, Missouri	3
A Pathologically Verified Case of Peripheral Intracranial Aneurysmal Formation With Massively Infiltrating Meningioma Cells	3
Pathological Characteristics of Malformations of Cortical Development in Golden Syrian Hamsters with LDLR Deficiency	3
Non-canonical IDH Mutation Frequency in IDH1-R132H-Negative Glioblastoma Patients Older Than 54 Years	3
Cephalic electroacupuncture restores learning and memory in rats with induced ischemic stroke via inhibition of NF-κB nuclear translocation	3
Elevated Oxidative Stress and DNA Damage in Cortical Neurons of Chemotherapy Patients	3
Asymmetry of Hippocampal Tau Pathology in Primary Age-Related Tauopathy and Alzheimer Disease	3
SARS-CoV-2 Brain Regional Detection, Histopathology, Gene Expression, and Immunomodulatory Changes in Decedents with COVID-19	3
Cycad Genotoxin Methylazoxymethanol Disrupts the Brain Ubiquitin-Proteasome Pathway, Tau and α-Synuclein, as Reported in ALS-PDC	3
In This Issue	3
In This Issue	3
The Epigenetic Regulator Jumonji Domain-Containing Protein 6 (JMJD6) Is Highly Expressed but Not Prognostic in IDH-Wildtype Glioblastoma Patients	3
Endothelial cell malfunction in unruptured intracranial aneurysm lesions revealed using a 3D-casted mold	3
Systematic Classification of Spina Bifida	3
In This Issue	3
β-Amyloid species production and tau phosphorylation in iPSC-neurons with reference to neuropathologically characterized matched donor brains	3
Corrigendum to: Cerebellar Pilocytic Astrocytoma with a Sacral Drop Metastasis in an Adult	3
In This Issue	3