OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Neuropathology and Experimental Neurology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
In This Issue	43
Transdifferentiation of metastatic melanoma into cerebellar angiosarcoma	37
Extensive Postnatal Brainstem Calcification in a Premature Infant	34
Dual white matter pathology in fetal holoprosencephaly featuring concurrent malformative and destructive features: A case series	34
Diagnostic yield of postmortem brain examination following premortem brain biopsy for neoplastic and nonneoplastic disease	33
Tissue clearing to examine glioma complexity in 3 dimensions	33
In This Issue	33
Myxoid glioneuronal tumors can harbor unusual PDGFRA alterations	31
Charcot Bouchard aneurysm: Case report and critical literature review	31
Revealing the potential role of hsa-miR-663a in modulating the PI3K-Akt signaling pathway via miRNA microarray in spinal muscular atrophy patient fibroblast-derived iPSCs	31
Identification of disease-associated molecular signatures in the Prp-TDP-43A315T mouse model of ALS: Toward preclinical biomarker development	30
Evaluation of 6 monoclonal antibodies against Ser129-phosphorylated α-synuclein: Critical role of proteinase K antigen retrieval and superior sensitivity of the D1R1R clone in human skin biopsies	27
A novel grading system combining histological grade and CDKN2A homozygous and hemizygous deletion to predict prognosis in IDH-mutant astrocytoma	26
Plasticity of synapses innervating spinal motor neurons after spinal cord injury in rhesus monkeys	25
ANKRD22 promotes glioma proliferation, migration, invasion, and epithelial-mesenchymal transition by upregulating E2F1-mediated MELK expression	22
AMPA receptors in Alzheimer disease: Pathological changes and potential therapeutic targets	21
Sevoflurane anesthesia during late gestation induces cognitive disorder in rat offspring via the TLR4/BDNF/TrkB/CREB pathway	19
Limbic-predominant age-related TDP-43 encephalopathy (LATE-NC): Co-pathologies and genetic risk factors provide clues about pathogenesis	19
Aberrant accumulation of phosphorylated BRCA1 in brainstem-type and cortical-type Lewy bodies in Lewy body disease	18
Meritorious Contributions to Neuropathology	18
Altered expression of human myxovirus resistance protein A in amyotrophic lateral sclerosis	18
Therapeutic potential and challenges of mesenchymal stem cells in neurological disorders: A concise analysis	18
Contribution of major histocompatibility complex class II immunostaining in distinguishing idiopathic inflammatory myopathy subgroups: A histopathological cohort study	18
Phosphorylation of Tau at Threonine 231 in Patients With Multiple System Atrophy and in a Mouse Model	18
C9orf72 proline-arginine dipeptide repeats disrupt the proteasome and perturb proteolytic activities	18

The comprehensive morphological and molecular characteristics of lipoastrocytoma: A case report	18
Increased efficacy of adipose-derived mesenchymal stem cells transduced with klotho in differentiation and maturation of oligodendrocytes in a mouse model of experimental autoimmune encephalomyelitis	18
Persistent increase of Nogo-A-positive cells and dynamic reduction in oligodendroglia lineage cells in white matter regions following experimental and clinical traumatic brain injury	17
METTL14/IGF2BP2-mediated m6A modification of PD-L1 promotes proliferation, metastasis, and immune escape in high-grade gliomas	16
Could conditioned medium be used instead of stem cell transplantation to repair spinal cord injury in animal models? Identifying knowledge gaps	16
Significant contralaterality of temporal-predominant neuroastroglial tauopathy and FTLD-TDP type C presenting with the right temporal variant FTD	15
Concurrent Pit-1 and SALL4 staining in primitive component of pituitary blastoma: A case report with clinicopathologic features including Cushing syndrome presentation, germline DICER1 mutation	15
Increased inflammasome protein expression identified in microglia from postmortem brains with schizophrenia	15
Immune Microenvironment and Lineage Tracing Help to Decipher Rosette-Forming Glioneuronal Tumors: A Multi-Omics Analysis	14
In This Issue	14
Detection of Gram-positive and Gram-negative bacteria in brain abscesses by 16S rRNA in situ hybridization	14
FGFR1 fusions in genomically and epigenetically bona fide glioblastoma, IDH-wildtype	14
COVID-19 could worsen cerebral amyloid angiopathy	14
ZFTA-fused supratentorial ependymoma with a novel fusion partner, DUX4	14
In This Issue	13
Acquired intradiploic epidermoid cyst: A rare case report with literature review	13
In This Issue	13
Long noncoding RNA KCNQ1OT1 aggravates cerebral infarction by regulating PTBT1/SIRT1 via miR-16-5p	13
Exercise-induced acute thrombosis of a cavernous sinus hemangioma	13
Angiogenic responses are enhanced by recombinant human erythropoietin in a model of periventricular white matter damage of neonatal rats through EPOR-ERK1 signaling	13
Histological appearance of topical hemostatic agents and materials in neuropathology	12
Spatially resolved transcriptomics reveals a unique disease signature and potential biomarkers for chronic traumatic encephalopathy	12
Automated deep learning segmentation of neuritic plaques and neurofibrillary tangles in Alzheimer disease brain sections using a proprietary software	12
METTL3-mediated maturation of miR-192-5p targets ATG7 to prevent Schwann cell autophagy in peripheral nerve injury	12
Performance of a condensed protocol to assess limbic-predominant age-related TDP-43 encephalopathy neuropathologic change	11
In This Issue	11
Correction to: Polymicrogyria with Dysmorphic Neurons in a Patient with SCN2A Mutation	11
Multifocal demyelinating leukoencephalopathy and oligodendroglial lineage cell loss with immune effector cell-associated neurotoxicity syndrome (ICANS) following CD19 CAR T-cell therapy for mantle cel	11
Historical review: The golden age of the Golgi method in human neuropathology	11
Merlin immunoreactivity fails to predict neurofibromatosis type 2 mutations in human meningiomas	11
Neuropathological features of SARS-CoV-2 delta and omicron variants	11
Persistence of Kii amyotrophic lateral sclerosis after the 2000s and its characteristic aging-related tau astrogliopathy	11
Correction to: Novel Glial Fibrillary Acidic Protein Variant in a Probable Adult-Onset Alexander Disease	11
A rare case of fibromuscular dysplasia involving the cervicocephalic arterial tree highlighting the neuropathological findings	10
Abnormal phosphorylation of protein tyrosine in neurodegenerative diseases	10
What every neuropathologist needs to know: Update on neuro infectious disease workups and consultation resources	10
Locus coeruleus TDP-43 pathology in a community-based cohort: Clinical and pathological correlates	10
Neuropathologic Findings in Elderly HIV-Positive Individuals	10
Neuropathologic Findings in Galloway-Mowat Syndrome 3 With a Novel OSGEP Variant	10
Correction to: Mapping the expression of endothelial adhesion receptors for Plasmodium falciparum -infected erythrocytes in fatal cerebral malaria in Mal	10
Perinatal hypoxic-ischemic brain injury: What’s behind the “ribbon effect”?	10
Reactive astrocytes in spinal cord injury: An analysis of heterogeneity based on temporality and spatiality, potential therapies, and limitations	9
CAPNON: A rare entity with long-term follow-up	9
Progestin-associated meningiomatosis with unusual schwannoma-like morphology	9
Relationship between promyelocytic leukemia protein nuclear bodies and TAR DNA-binding protein-43 aggregation in spinal anterior horn cells in sporadic amyotrophic lateral sclerosis	9
Temporal progression of axonal degeneration in the visual system in experimental autoimmune encephalomyelitis: Insights from high-resolution neuropathology	9
Differential Vulnerability of Hippocampal Subfields in Primary Age-Related Tauopathy and Chronic Traumatic Encephalopathy	9
Analysis of a large case series of fatal familial insomnia to determine tests with the highest diagnostic value	9
Low clinical sensitivity and unexpectedly high incidence for neuropathologically diagnosed progressive supranuclear palsy	9
NOD-like receptor X1 promotes autophagy and inactivates NLR family pyrin domain containing 3 inflammasome signaling by binding autophagy-related gene 5 to alleviate cerebral ischemia/reperfusion-induc	8

Efficacy of deep brain stimulation for neuronal intranuclear inclusion disease tremor-dominant subtype	8
Atherogenic-like lesions associated with a progressive chronic vascular degeneration in a rat model of repetitive low-level blast brain injury	8
NAA10 overexpression dictates distinct epigenetic, genetic, and clinicopathological characteristics in adult gliomas	8
Biopsy-proven granulomatous neuromyopathy in a case of Blau syndrome	7
E-cadherin expression and gene expression profiles in corticotroph pituitary neuroendocrine tumor subtypes	7
Chronic traumatic encephalopathy and aging-related tau astrogliopathy in community-dwelling older persons with and without moderate-to-severe traumatic brain injury	7
A novel hypertensive rat model of cerebral small vessel disease: Pathological, cognitive, and neuroimaging implications	7
In This Issue	7
DNA methylation profiling and histologic analysis of sellar TTF-1-positive papillary epithelial tumor supports a novel CNS entity	7
Alzheimer disease-associated tau post-translational modification mimics impact tau propagation and uptake	7
In This Issue	7
Transthyretin immunohistochemistry on muscle and nerve biopsies detects hereditary and wild-type transthyretin amyloidosis with high sensitivity and specificity	7
RagC and Map4K3 deficiency in high-grade gliomas drives proliferation and modulates mTORC1-dependent cellular functions	7
Clinicopathological study of chronic traumatic encephalopathy pathology in a population-based cohort	7
Donald L. Price, MD 1935–2023	7
Prevalence of Lewy pathology in essential tremor is twice as high as expected: A plausible explanation for the enhanced risk for Parkinson disease seen in essential tremor cases	6
Dexmedetomidine Inhibits NF-κB-Transcriptional Activity in Neurons Undergoing Ischemia-Reperfusion by Regulating O-GlcNAcylation of SNW1	6
α-Synuclein distribution in olfactory mucosa and skin nerves in Parkinson disease associated with an EIF4G1 gene mutation	6
In This Issue	6
Rapid assessment of MGMT promoter methylation status by droplet digital polymerase chain reaction on intraoperative smear preparation: A proof-of-concept	6
Antemortem radiologic and histopathologic presentation of Marchiafava-Bignami disease	6
C5aR antagonism by PMX205 confers neuroprotection in hypoxic-ischemic brain injury models via anti-inflammatory and anti-apoptotic mechanisms	6
A Rare Diagnostic Challenge: Choroid Plexus Xanthogranuloma Harboring a Low-Grade Marginal Zone B-Cell Lymphoma	6
LncRNA HAGLR promotes the proliferation, migration, and neurotrophic factor production of Schwann cells via miR-204/CDK5R1 after sciatic nerve injury	6
Chronological Changes in the Expression Pattern of Hippocampal Prion Proteins During Disease Progression in Sporadic Creutzfeldt-Jakob Disease MM1 Subtype	6
Muscle mitochondrial changes in antisynthetase syndrome and other idiopathic inflammatory myopathies	6
A pleomorphic xanthoastrocytoma highlighting the morphological heterogeneity of this uncommon tumor	6
Bone Marrow Stem Cell-Exo-Derived TSG-6 Attenuates 1-Methyl-4-Phenylpyridinium+-Induced Neurotoxicity via the STAT3/miR-7/NEDD4/LRRK2 Axis	6
Chronic traumatic encephalopathy pathognomonic lesions occurring in isolation adjacent to infiltrative and non-infiltrative white matter lesions	6
Neuropathology of classic myotonic dystrophy type 1 is characterized by both early initiation of primary age-related tauopathy of the hippocampus and unique 3-repeat tauopathy of the brainstem	6
Authors’ response to: “Alexander disease genetics: Beyond GFAP exon sequencing?”	5
Frontotemporal Lobar Degeneration With Unclassifiable 4-Repeat Tauopathy Mimicking Globular Glial Tauopathy	5
Molecular characterization of benign intracranial glioependymal and arachnoid cysts suggest heterogeneous mechanisms of action	5
Cavernous sinus hemangioma: Histopathological spectrum of 8 cases	5
In situ seeding assay: A novel technique for direct tissue localization of bioactive tau	5
PAS+/PASD- intracytoplasmic glycogen is not specific for clear cell meningioma	5
A comparison of CDKN2A status in gliomas using different techniques: The loss of p16 as a surrogate marker	5
In This Issue	5
The association between virus-induced spinal cord pathology and the genetic background of the host	5
Expanding the differential diagnosis for dural-based spindle cell neoplasms: A report of a rare GLI1 -altered mesenchymal tumor of the CNS	5
Cortical variant multiple sclerosis presenting clinically as Lewy body dementia	5
Prostate-Specific Membrane Antigen Expression in Meningioma: A Promising Theranostic Target	5
Cardiotrophin-like cytokine factor 1 regulated by Sry-related HMG-box transcription factor 9 promotes malignant behavior and immune evasion of glioblastoma multiforme	5
β-Amyloid species production and tau phosphorylation in iPSC-neurons with reference to neuropathologically characterized matched donor brains	5
Intratumoral heterogeneity of MYC status and methylation subtyping in group 3 medulloblastoma: A case report	5
Comparative analysis of histopathological parameters, genome-wide copy number alterations, and variants in genes involved in cell cycle regulation in chordomas of the skull base and sacrum	5
Comorbidities in early-onset sporadic versus presenilin-1 mutation-associated Alzheimer disease dementia: Evidence for dependency on Alzheimer disease neuropathological changes	5
Skin Biopsy as a Novel Diagnostic Aid in Immune-Mediated Neuropathies	5
Impact of COVID-19 pandemic on neuropathology service: Experience at one Canadian center	5
Unusual immunohistochemical profiles in hemangioblastomas and their relevance in differential diagnosis: A comprehensive study of 112 cases	5
In This Issue	5
Hippocampal synaptic alterations associated with tau pathology in primary age-related tauopathy	5
Different cortical and subcortical astroglial responsiveness in rats with acute liver failure	5
A custom next-generation sequencing panel for 1p/19q codeletion and mutational analysis in gliomas	4
Cytoplasmic expression of trans-active response DNA-binding protein-43 in aged mice display hippocampal sclerosis-like degeneration and neuronal loss with reduced lifespan	4
Intracellular calcium dysregulation in heart and brain diseases: Insights from induced pluripotent stem cell studies	4
Gliomas with succinate dehydrogenase deficiency: A case series and brief review of the literature of oncometabolite-driven gliomagenesis	4
Altered 5-HT2A/C receptor binding in the medulla oblongata in the sudden infant death syndrome (SIDS): Part II. Age-associated alterations in serotonin receptor binding profiles within medullary nucle	4
Comprehensive analysis of distinct circadian clock subtypes of adult diffuse glioma and their associations with clinicopathological, genetic, and epigenetic profiles	4
Ependymal-like tumor with SMARCA2::PLAGL1 fusion: A novel molecular driver in neuroepithelial tumors with PLAGL1	4
In This Issue	4
In This Issue	4
In severe ADNC, hippocampi with comorbid LATE-NC and hippocampal sclerosis have substantially more astrocytosis than those with LATE-NC or hippocampal sclerosis alone	4
Comparison of multiple quantitative strategies for neuropathologic image analyses	4
Downregulating Cdk5 reverses hippocampal neuron ferroptosis by regulating the AMP-activated protein kinase pathway and “M1” polarized microglia	4
EGFR Exon 20 Insertion in Bithalamic and Unithalamic Glioma: A Report of 2 Cases and Literature Review	4
Alteration of Vesicle-Associated Membrane Protein-Binding Protein B in α-Synuclein Aggregates in Lewy Body Disease	4
Integrating molecular analyses with the 2021 WHO classification of adult pilocytic astrocytomas	4
In This Issue	4
Digital Histological Study of Neocortical Grey and White Matter Tau Burden Across Tauopathies	4
Identification of diagnostic biomarkers for relapsing-remitting multiple sclerosis in plasma by mass spectrometry-based proteomics	4
Preanalytic variable effects on segmentation and quantification machine learning algorithms for amyloid-β analyses on digitized human brain slides	4
In This Issue	4
Comparing Gallyas and AT8 staining for quantification of tau pathology in subregions of the human hippocampus	4