OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Neuropathology and Experimental Neurology is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Application of Genome-Wide DNA Methylation Analysis to Differentiate a Case of Radiation-Induced Glioblastoma From Late-Relapsed Medulloblastoma	38
ANKRD22 promotes glioma proliferation, migration, invasion, and epithelial-mesenchymal transition by upregulating E2F1-mediated MELK expression	37
AMPA receptors in Alzheimer disease: Pathological changes and potential therapeutic targets	35
Charcot Bouchard aneurysm: Case report and critical literature review	31
Tissue clearing to examine glioma complexity in 3 dimensions	24
Diagnostic yield of postmortem brain examination following premortem brain biopsy for neoplastic and nonneoplastic disease	23
Dual white matter pathology in fetal holoprosencephaly featuring concurrent malformative and destructive features: A case series	23
Extensive Postnatal Brainstem Calcification in a Premature Infant	22
MicroRNA-155-5p Targets SKP2, Activates IKKβ, Increases Aβ Aggregation, and Aggravates a Mouse Alzheimer Disease Model	21
Transdifferentiation of metastatic melanoma into cerebellar angiosarcoma	20
Pediatric Gliomas Presenting with Gliomatosis-Like Spread, Lack of Contrast Enhancement, EGFR Mutation, and TERT Promoter Variants	20
Revealing the potential role of hsa-miR-663a in modulating the PI3K-Akt signaling pathway via miRNA microarray in spinal muscular atrophy patient fibroblast-derived iPSCs	20
A novel grading system combining histological grade and CDKN2A homozygous and hemizygous deletion to predict prognosis in IDH-mutant astrocytoma	19
In This Issue	19
Limbic-predominant age-related TDP-43 encephalopathy (LATE-NC): Co-pathologies and genetic risk factors provide clues about pathogenesis	18
Evaluation of 6 monoclonal antibodies against Ser129-phosphorylated α-synuclein: Critical role of proteinase K antigen retrieval and superior sensitivity of the D1R1R clone in human skin biopsies	18
Persistent increase of Nogo-A-positive cells and dynamic reduction in oligodendroglia lineage cells in white matter regions following experimental and clinical traumatic brain injury	17
Sevoflurane anesthesia during late gestation induces cognitive disorder in rat offspring via the TLR4/BDNF/TrkB/CREB pathway	17
The comprehensive morphological and molecular characteristics of lipoastrocytoma: A case report	16
Phosphorylation of Tau at Threonine 231 in Patients With Multiple System Atrophy and in a Mouse Model	16
Pathological Characteristics of Malformations of Cortical Development in Golden Syrian Hamsters with LDLR Deficiency	16
Altered expression of human myxovirus resistance protein A in amyotrophic lateral sclerosis	15
Could conditioned medium be used instead of stem cell transplantation to repair spinal cord injury in animal models? Identifying knowledge gaps	15
Meritorious Contributions to Neuropathology	15
Corrigendum to: Cerebellar Pilocytic Astrocytoma with a Sacral Drop Metastasis in an Adult	14

In This Issue	14
Aberrant accumulation of phosphorylated BRCA1 in brainstem-type and cortical-type Lewy bodies in Lewy body disease	13
Therapeutic potential and challenges of mesenchymal stem cells in neurological disorders: A concise analysis	13
Elevated Oxidative Stress and DNA Damage in Cortical Neurons of Chemotherapy Patients	13
Contribution of major histocompatibility complex class II immunostaining in distinguishing idiopathic inflammatory myopathy subgroups: A histopathological cohort study	13
Increased inflammasome protein expression identified in microglia from postmortem brains with schizophrenia	13
C9orf72 proline-arginine dipeptide repeats disrupt the proteasome and perturb proteolytic activities	13
Concurrent Pit-1 and SALL4 staining in primitive component of pituitary blastoma: A case report with clinicopathologic features including Cushing syndrome presentation, germline DICER1 mutation	12
Histological appearance of topical hemostatic agents and materials in neuropathology	12
Acupuncture at ST36 Alleviates the Behavioral Disorder of Autistic Rats by Inhibiting TXNIP-Mediated Activation of NLRP3	12
ZFTA-fused supratentorial ependymoma with a novel fusion partner, DUX4	12
Immune Microenvironment and Lineage Tracing Help to Decipher Rosette-Forming Glioneuronal Tumors: A Multi-Omics Analysis	12
Automated deep learning segmentation of neuritic plaques and neurofibrillary tangles in Alzheimer disease brain sections using a proprietary software	12
Advantages of an Automated Method Compared With Manual Methods for the Quantification of Intraepidermal Nerve Fiber in Skin Biopsy	12
Distinct Patterns of Amyloid Pathology in Autopsies of Transthyretin S77Y and A97S Amyloidosis: Significance of Symptomatology and Cell Biology	11
Detection of Gram-positive and Gram-negative bacteria in brain abscesses by 16S rRNA in situ hybridization	11
Significant contralaterality of temporal-predominant neuroastroglial tauopathy and FTLD-TDP type C presenting with the right temporal variant FTD	11
Performance of a condensed protocol to assess limbic-predominant age-related TDP-43 encephalopathy neuropathologic change	11
COVID-19 could worsen cerebral amyloid angiopathy	11
Angiogenic responses are enhanced by recombinant human erythropoietin in a model of periventricular white matter damage of neonatal rats through EPOR-ERK1 signaling	11
Multifocal demyelinating leukoencephalopathy and oligodendroglial lineage cell loss with immune effector cell-associated neurotoxicity syndrome (ICANS) following CD19 CAR T-cell therapy for mantle cel	11
In This Issue	10
Acquired intradiploic epidermoid cyst: A rare case report with literature review	10
In This Issue	10
Neuropathological features of SARS-CoV-2 delta and omicron variants	10
In This Issue	10
Long noncoding RNA KCNQ1OT1 aggravates cerebral infarction by regulating PTBT1/SIRT1 via miR-16-5p	10
METTL3-mediated maturation of miR-192-5p targets ATG7 to prevent Schwann cell autophagy in peripheral nerve injury	9
In This Issue	9
Historical review: The golden age of the Golgi method in human neuropathology	9
A Rare Presentation of Low-Grade Prostate Adenocarcinoma as Delayed Pineal Region Metastasis: A Case Report and Review of Multicenter Clinical Experience in Prostate Carcinoma Brain Metastases	9
Correction to: Polymicrogyria with Dysmorphic Neurons in a Patient with SCN2A Mutation	9
Correction to: Novel Glial Fibrillary Acidic Protein Variant in a Probable Adult-Onset Alexander Disease	9
Novel RAF Fusions in Pediatric Low-Grade Gliomas Demonstrate MAPK Pathway Activation	9
Persistence of Kii amyotrophic lateral sclerosis after the 2000s and its characteristic aging-related tau astrogliopathy	9
In This Issue	9
In This Issue	9
Neuropathologic Findings in Elderly HIV-Positive Individuals	9
Adenocarcinoma Arising in a Yolk Sac Tumor of the Pineal Gland	9
Perinatal hypoxic-ischemic brain injury: What’s behind the “ribbon effect”?	9
Optimized Flow Cytometry Strategy for Phenotyping Intramuscular Leukocytes: Application to the Evaluation of Myopathological Processes	8
Paraneoplastic Lower Motor Neuron Disease	8
Neuropathologic Findings in Galloway-Mowat Syndrome 3 With a Novel OSGEP Variant	8
Activating BRAF G469A Missense Mutation in a Pediatric Patient With High-Grade Glioma	8
Abnormal phosphorylation of protein tyrosine in neurodegenerative diseases	8
NOD-like receptor X1 promotes autophagy and inactivates NLR family pyrin domain containing 3 inflammasome signaling by binding autophagy-related gene 5 to alleviate cerebral ischemia/reperfusion-induc	8
NAA10 overexpression dictates distinct epigenetic, genetic, and clinicopathological characteristics in adult gliomas	8
Analysis of a large case series of fatal familial insomnia to determine tests with the highest diagnostic value	8
Novel Glial Fibrillary Acidic Protein Variant in a Probable Adult-Onset Alexander Disease	8
A Comparative Study of Site-Specific Distribution of Aging-Related Tau Astrogliopathy and Its Risk Factors Between Alzheimer Disease and Cognitive Healthy Brains: The Hisayama Study	8

Discrepancy between Mild Muscle Pathology and Severe Muscular Compromise in COVID-19 Suggests Nonviral Etiologies	8
Progestin-associated meningiomatosis with unusual schwannoma-like morphology	8
A rare case of fibromuscular dysplasia involving the cervicocephalic arterial tree highlighting the neuropathological findings	8
What every neuropathologist needs to know: Update on neuro infectious disease workups and consultation resources	8
Differential Vulnerability of Hippocampal Subfields in Primary Age-Related Tauopathy and Chronic Traumatic Encephalopathy	7
Alzheimer disease-associated tau post-translational modification mimics impact tau propagation and uptake	7
In This Issue	7
Microglia Activation in the Midbrain of the Human Neonate: The Effect of Perinatal Hypoxic-Ischemic Injury	7
Donald L. Price, MD 1935–2023	7
Efficacy of deep brain stimulation for neuronal intranuclear inclusion disease tremor-dominant subtype	7
Low clinical sensitivity and unexpectedly high incidence for neuropathologically diagnosed progressive supranuclear palsy	7
In This Issue	7
Molecular Alterations in Meningioangiomatosis Causing Epilepsy	6
Chronic traumatic encephalopathy pathognomonic lesions occurring in isolation adjacent to infiltrative and non-infiltrative white matter lesions	6
A Rare Diagnostic Challenge: Choroid Plexus Xanthogranuloma Harboring a Low-Grade Marginal Zone B-Cell Lymphoma	6
A pleomorphic xanthoastrocytoma highlighting the morphological heterogeneity of this uncommon tumor	6
Chronological Changes in the Expression Pattern of Hippocampal Prion Proteins During Disease Progression in Sporadic Creutzfeldt-Jakob Disease MM1 Subtype	6
Chronic traumatic encephalopathy and aging-related tau astrogliopathy in community-dwelling older persons with and without moderate-to-severe traumatic brain injury	6
Subarachnoid Fibrosis in Human Post-Traumatic Syringomyelia: A Prospective Observational Clinical Study	6
Appreciation of Reviewers	6
Entrapped Megakaryocytes in the Microvasculature of Brain Tissues are not Specific to COVID-19 but can be Seen Across a Spectrum of Acute Lung Injuries	6
Dexmedetomidine Inhibits NF-κB-Transcriptional Activity in Neurons Undergoing Ischemia-Reperfusion by Regulating O-GlcNAcylation of SNW1	6
Polymorphous Low-Grade Neuroepithelial Tumor of the Young (PLNTY): Molecular Profiling Confirms Frequent MAPK Pathway Activation	6
The Epigenetic Regulator Jumonji Domain-Containing Protein 6 (JMJD6) Is Highly Expressed but Not Prognostic in IDH-Wildtype Glioblastoma Patients	6
Prevalence of Lewy pathology in essential tremor is twice as high as expected: A plausible explanation for the enhanced risk for Parkinson disease seen in essential tremor cases	6
FUS Is Not Mislocalized in Spinal Motor Neurons Derived From Human Induced Pluripotent Stem Cells of Main Non-FUS ALS Subtypes	6
LncRNA HAGLR promotes the proliferation, migration, and neurotrophic factor production of Schwann cells via miR-204/CDK5R1 after sciatic nerve injury	6
E-cadherin expression and gene expression profiles in corticotroph pituitary neuroendocrine tumor subtypes	6
Bone Marrow Stem Cell-Exo-Derived TSG-6 Attenuates 1-Methyl-4-Phenylpyridinium+-Induced Neurotoxicity via the STAT3/miR-7/NEDD4/LRRK2 Axis	6
In This Issue	6
A Pathologically Verified Case of Peripheral Intracranial Aneurysmal Formation With Massively Infiltrating Meningioma Cells	6
Neuropathology of classic myotonic dystrophy type 1 is characterized by both early initiation of primary age-related tauopathy of the hippocampus and unique 3-repeat tauopathy of the brainstem	6
DNA methylation profiling and histologic analysis of sellar TTF-1-positive papillary epithelial tumor supports a novel CNS entity	6
Bioengineered Models to Study Microenvironmental Regulation of Glioblastoma Metabolism	5
In This Issue	5
Hippocampal synaptic alterations associated with tau pathology in primary age-related tauopathy	5
Alterations in the RB Pathway With Inactivation of RB1 Characterize Glioblastomas With a Primitive Neuronal Component	5
β-Amyloid species production and tau phosphorylation in iPSC-neurons with reference to neuropathologically characterized matched donor brains	5
Prostate-Specific Membrane Antigen Expression in Meningioma: A Promising Theranostic Target	5
α-Synuclein distribution in olfactory mucosa and skin nerves in Parkinson disease associated with an EIF4G1 gene mutation	5
Different cortical and subcortical astroglial responsiveness in rats with acute liver failure	5
In situ seeding assay: A novel technique for direct tissue localization of bioactive tau	5
Fast Progression in Amyotrophic Lateral Sclerosis Is Associated With Greater TDP-43 Burden in Spinal Cord	5
Authors’ response to: “Alexander disease genetics: Beyond GFAP exon sequencing?”	4
Frontotemporal Lobar Degeneration With Unclassifiable 4-Repeat Tauopathy Mimicking Globular Glial Tauopathy	4
Molecular characterization of benign intracranial glioependymal and arachnoid cysts suggest heterogeneous mechanisms of action	4
Digital Histological Study of Neocortical Grey and White Matter Tau Burden Across Tauopathies	4
A custom next-generation sequencing panel for 1p/19q codeletion and mutational analysis in gliomas	4
In This Issue	4
In This Issue	4
Intracellular calcium dysregulation in heart and brain diseases: Insights from induced pluripotent stem cell studies	4
Cavernous sinus hemangioma: Histopathological spectrum of 8 cases	4
Comorbidities in early-onset sporadic versus presenilin-1 mutation-associated Alzheimer disease dementia: Evidence for dependency on Alzheimer disease neuropathological changes	4
Clinical Importance of Molecular Testing in Neuromuscular Choristomas	4
Preanalytic variable effects on segmentation and quantification machine learning algorithms for amyloid-β analyses on digitized human brain slides	4
Medial Gap: A Structural Factor at the Arterial Bifurcation Aggravating Hemodynamic Insult	4
Cortical variant multiple sclerosis presenting clinically as Lewy body dementia	4
Comparative analysis of histopathological parameters, genome-wide copy number alterations, and variants in genes involved in cell cycle regulation in chordomas of the skull base and sacrum	4
Impact of COVID-19 pandemic on neuropathology service: Experience at one Canadian center	4
Pathology Features of Immune and Inflammatory Myopathies, Including a Polymyositis Pattern, Relate Strongly to Serum Autoantibodies	4
In severe ADNC, hippocampi with comorbid LATE-NC and hippocampal sclerosis have substantially more astrocytosis than those with LATE-NC or hippocampal sclerosis alone	4
PHOX2B as a Reliable Marker for Neuroblastoma in Tissue and Cytology Specimens	4
In This Issue	4
Skin Biopsy as a Novel Diagnostic Aid in Immune-Mediated Neuropathies	4