Journal of Neurochemistry

Papers
(The median citation count of Journal of Neurochemistry is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
Colony‐stimulating factor‐1 receptor inhibition attenuates microgliosis and myelin loss but exacerbates neurodegeneration in the chronic cuprizone model136
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The antiseizure medication valproate increases hemichannel activity found in brain cells, which could worsen disease outcomes80
The following article for this Special Issue was previously published and can be found in its respective issue online: “Amyloid processing in COVID‐19‐associated neurological syndromes”80
Synaptotagmin‐11 regulates immune functions of microglia in vivo69
A novel strategy for deliveringNiemann‐Pick typeC2proteins across the blood–brain barrier using the brain endothelial‐specificAAV‐BR1virus68
ESN‐YMS64
Issue Information56
Dendrimer nanotherapy targeting of glial dysfunction improves inflammation and neurobehavioral phenotype in adult female Mecp2‐heterozygous mouse model of Rett syndrome55
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IL‐1β/IL‐1R1 signaling is involved in the propagation of α‐synuclein pathology of the gastrointestinal tract to the brain49
HSP110 is a modulator of amyloid beta (Aβ) aggregation and proteotoxicity48
Bioenergetic and excitotoxic determinants of cofilactin rod formation47
The activation of inflammatory responses in the brain is potentiated by over‐expressing acetylcholinesterase in myeloid lineage of transgenic mice46
MicroRNA‐29b‐3p degenerates terminally differentiated dopaminergic SH‐SY5Y cells by perturbation of mitochondrial functions46
PPARβ/δ Activation Improves Corticosterone‐Induced Oxidative Stress Damage in Astrocytes by Targeting UBR5/ATM Signaling45
Upregulation of FMRP Is Involved in Neuropathic Pain by Regulating GluN2B Activation in Rat Spinal Cord41
COVID‐19 and the impact on Alzheimer's disease pathology40
Dynamics of Neuronal and Astrocytic Energy Molecules in Epilepsy39
Serum amyloid A facilitates expansion of CD4+ T cell and CD19+ B cell subsets implicated in the severity of myasthenia gravis patients37
Pigment epithelium‐derived factor (PEDF) and derived peptides promote survival and differentiation of photoreceptors and induce neurite‐outgrowth in amacrine neurons37
Nimodipine accelerates the restoration of functional hyperemia during spreading oligemia36
DJ‐1 regulates astrocyte activation through miR‐155/SHP‐1 signaling in cerebral ischemia/reperfusion injury35
Enhanced tyrosine hydroxylase activity induces oxidative stress, causes accumulation of autotoxic catecholamine metabolites, and augments amphetamine effects in vivo33
Sex‐specific pleiotropic changes in emotional behavior and alcohol consumption in human α‐synuclein A53T transgenic mice during early adulthood33
From molecules to behavior: Implications for perineuronal net remodeling in learning and memory33
Apolipoprotein E ε4 disrupts oligodendrocyte differentiation by interfering with astrocyte‐derived lipid transport32
Fundamental Neurochemistry Review: GABAA receptor neurotransmission and epilepsy: Principles, disease mechanisms and pharmacotherapy29
Sex‐dependent differences in the ability of nicotine to modulate discrimination learning and cognitive flexibility in mice29
Milestone Review: Metabolic dynamics of glutamate and GABA mediated neurotransmission — The essential roles of astrocytes29
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Emerging_Group_Leaders_Symposia28
Acknowledgement of reviewers28
Distinct dose‐dependent effects of methamphetamine on real‐time dopamine transmission in the rat nucleus accumbens and behaviors28
Ependymal cells undergo astrocyte‐like reactivity in response to neuroinflammation27
Protein arginine methyltransferase 8 modulates mitochondrial bioenergetics and neuroinflammation after hypoxic stress27
Does the inability of CA1 area to respond to ischemia with early rapid adenosine release contribute to hippocampal vulnerability?26
EDITOR SPOTLIGHT: Interview with Brain Imaging Special Issue guest editors Victor Villemagne and Yulong Li26
Issue Information26
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The sphingosine 1‐phosphate analogue, FTY720, modulates the lipidomic signature of the mouse hippocampus25
AENK ameliorates cognitive impairment and prevents Tau hyperphosphorylation through inhibiting AEP‐mediated cleavage of SET in rats with ischemic stroke25
Mechanistic stoichiometric relationship between the rates of neurotransmission and neuronal glucose oxidation: Reevaluation of and alternatives to the pseudo‐malate‐aspartate shuttle model25
Psilocybin as a lead candidate molecule in preclinical therapeutic studies of psychiatric disorders: A systematic review25
α‐Synuclein induces deficiency in clathrin‐mediated endocytosis through inhibiting synaptojanin1 expression25
Transcriptome profile of subsynaptic myonuclei at the neuromuscular junction in embryogenesis24
Monitoring conformational changes in the human neurotransmitter transporter homologue LeuT with 19F‐NMR spectroscopy24
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The Evolution of Experimental Rodent Models for Prion Diseases22
Exploring the Structural Dynamics of LeuT Using EPR Spectroscopy: A Focus on Transmembrane Helix 1022
Ferroptosis mediated by TNFSF9 interferes in acute ischaemic stroke reperfusion injury with the progression of acute ischaemic stroke21
Exploring the reduction in aquaporin‐4 and increased expression of ciliary neurotrophic factor with the frontal–striatal gliosis induced by chronic high‐fat dietary stress21
Clinical, molecular, physiologic, and therapeutic feature of patients with CHRNA4 and CHRNB2 deficiency: A systematic review21
RNA editing‐mediated regulation of calcium‐dependent activator protein for secretion (CAPS1) localization and its impact on synaptic transmission21
Novel single‐nucleus transcriptomics unravels developmental and functionally controlled principles of mammalian neuromuscular junctions21
Characterisation and automated quantification of induced seizure‐related behaviours in Xenopus laevis tadpoles21
The relationship between serum neurofilament light chain and glial fibrillary acidic protein with the REM sleep behavior disorder subtype of Parkinson's disease21
Cerebrospinal fluid levels of L‐glutamate signal central inflammatory neurodegeneration in multiple sclerosis20
Morphine‐induced kinase activation and localization in the periaqueductal gray of male and female mice20
Roles of metabotropic signaling of nicotine receptors in the development and maintenance of nicotine reward through regulation of dopamine D3 receptor expression20
The polyphenol EGCG directly targets intracellular amyloid‐β aggregates and promotes their lysosomal degradation20
In memoriam: Frode Fonnum (1937–2023)20
The multifaceted roles of the brain glycogen20
Dysregulation of circadian clock gene expression patterns in a treatment‐resistant animal model of depression20
Single‐cell RNA‐seq uncovers novel metabolic functions of Schwann cells beyond myelination19
Extracellular vesicles in the study of Alzheimer's and Parkinson's diseases: Methodologies applied from cells to biofluids19
Differential regulation of nucleus accumbens glutamate and GABA in obesity‐prone and obesity‐resistant rats19
Voltage‐gated sodium channels in genetic epilepsy: up and down of excitability19
Chronic ecologically relevant stress effects on reverse‐translated touchscreen assays of reward responsivity and attentional processes in male rats: Implications for depression19
Viscerosensory signalling to the nucleus accumbens via the solitary tract nucleus19
Neurotensin and energy balance19
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Poster Sessions A19
TBC1Domain Family Member 25 deficiency aggravates cerebral ischemia‐reperfusion injury via TAK1‐JNK/p38 pathway19
Phosphacan acts as a repulsive cue in murine and rat cerebellar granule cells in a TAG‐1/GD3 rafts‐dependent manner19
Roles of eukaryotic elongation factor 2 kinase (eEF2K) in neuronal plasticity, cognition, and Alzheimer disease19
Endonuclease VIII‐like 1 deficiency potentiates nigrostriatal dopaminergic neuron degeneration in a male mouse model of Parkinson's disease18
Calcium‐Dependent Signaling in Astrocytes: Downstream Mechanisms and Implications for Cognition18
Preface to the Special Issue “Matrix Metalloproteinases in Health and Disease”18
Structural amyloid plaque polymorphism is associated with distinct lipid accumulations revealed by trapped ion mobility mass spectrometry imaging18
Circulating metabolites associated with incident myocardial infarction and stroke: A prospective cohort study of 90 438 participants18
A neurodegeneration gene, WDR45, links impaired ferritinophagy to iron accumulation18
Issue Information18
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Association of serum lipidomic profiles with risk of intracranial aneurysm: A Mendelian randomization study17
Molecular targets of endothelial phosphatidic acid regulating major depressive disorder17
Contribution of ceramides metabolism in psychiatric disorders17
Issue Information17
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α7 nicotinic receptors play a role in regulation of cardiac hemodynamics17
Poster Sessions Wednesday/Thursday17
Experimental approaches for altering the expression of Abeta‐degrading enzymes17
(Re)building the nervous system: A review of neuron–glia interactions from development to disease17
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Issue Information16
Diet‐Induced Obesity in the Rat Impairs Sphingolipid Metabolism in the Brain and This Metabolic Dysfunction Is Transmitted to the Offspring via Both the Maternal and the Paternal Lineage16
Altered metabolic function induced by Aβ‐oligomers and PSEN1 mutations in iPSC‐derived astrocytes16
Long‐term neurological dysfunction associated with COVID‐19: Lessons from influenza and inflammatory diseases?16
Presenilin deficiency enhances tau phosphorylation and its secretion16
Altered Mitochondrial Bioenergetics and Calcium Kinetics in Young‐Onset PLA2G6 Parkinson's Disease iPSCs16
Focal acetylcholinergic modulation of the human midcingulo‐insular network during attention: Meta‐analytic neuroimaging and behavioral evidence16
Correction to “Constitutive alpha‐secretase cleavage of the beta‐amyloid precursor protein in the furin‐deficient LoVo cell line: involvement of the pro‐hormone convertase 7 and the disinte16
Nanobodies against the myelin enzyme CNPase as tools for structural and functional studies16
Demethylase FTO Regulates P2X3R Expression Contributing to the Mechanism of Hyperalgesia in Lumbar Disc Herniation16
Metabolic aspects of genetic ion channel epilepsies15
Molecular insights into psychedelic drug action15
Issue Information15
Book Review: Posttraumatic Epilepsy: Basic and Clinical Aspects (Jonak, Peterson and Binder; Academic Press, 2023)15
Ferroptosis as a mechanism of neurodegeneration in Alzheimer's disease15
Spreading depolarizations pose critical energy challenges in acute brain injury15
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Issue Information15
Reviewer List15
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Regulation of Dendrite and Dendritic Spine Formation by TCF2014
Understanding stress‐induced transmission of peripherally derived factors into the brain and responses in non‐neuronal cells14
Brain‐specific glycosylation of protein tyrosine phosphatase receptor type Z (PTPRZ) marks a demyelination‐associated astrocyte subtype14
Identification of residues in the first transmembrane domain of the P2X7 that regulates receptor trafficking, sensitization, and dye uptake function14
Improving neuropathic pain treatment – by rigorous stratification from bench to bedside14
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Amyloid beta 1‐40 and 1‐42 fibril ratios and maturation level cause conformational differences with minimal impact on autophagy and cytotoxicity14
Strain‐dependent role of copper in prion disease through binding to histidine residues in the N‐terminal domain of prion protein14
Circulating medium‐ and long‐chain acylcarnitines are associated with plasma P‐tau181 in cognitively normal older adults13
Lipidome changes in alcohol‐related brain damage13
Selective activation and down‐regulation of Trk receptors by neurotrophins in human neurons co‐expressing TrkB and TrkC13
Thirty years of BDNF study in central myelination: From biology to therapy13
Omega‐3 polyunsaturated fatty acids and Parkinson's disease: A systematic review of animal studies13
Up‐regulation of miR‐335 and miR‐674‐3p in the rostral ventrolateral medulla contributes to stress‐induced hypertension13
Gas5 regulates early‐life stress‐induced anxiety and spatial memory13
Dissecting cell‐type‐specific pathways in medial entorhinal cortical‐hippocampal network for episodic memory13
Regulation of CNS Lipids by Protease Activated Receptor 113
Ganglioside GD3 is up‐regulated in microglia and regulates phagocytosis following global cerebral ischemia13
Attenuated responses to attention‐modulating drugs in the neuroligin‐3R451C mouse model of autism13
Maternal history of Alzheimer's disease predisposes to altered serum cholesterol levels in adult offspring13
A biallelic mutation in CACNA2D2 associated with developmental and epileptic encephalopathy affects calcium channel‐dependent as well as synaptic functions of α2δ‐213
From BBB to PPP: Bioenergetic requirements and challenges for oligodendrocytes in health and disease13
Reactive astrogliosis: A friend or foe in the pathogenesis of Alzheimer’s disease13
Kainate receptor modulation of glutamatergic synaptic transmission in the CA2 region of the hippocampus13
Phase separation of the mammalian prion protein: Physiological and pathological perspectives13
Issue Information13
Inhibiting Brd4 alleviated PTSD‐like behaviors and fear memory through regulating immediate early genes expression and neuroinflammation in rats12
Sex and brain region‐specific regulation of serotonin transporter activity in synaptosomes in guanine nucleotide‐binding protein G(q) alpha knockout mice12
PARP1 in the intersection of different DNA repair pathways, memory formation, and sleep pressure in neurons12
Preface to the special issue “Neuroimmunology”12
Toward discovering a novel family of peptides targeting neuroinflammatory states of brain microglia and astrocytes12
Issue Information12
Selenomethionine mis‐incorporation and redox‐dependent voltage‐gated sodium channel gain of function12
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TRIM9 Controls Growth Cone Responses to Netrin Through DCC and UNC5C12
In Vivo Assessment of Cortical Astrocyte Network Dysfunction During Autoimmune Demyelination: Correlation With Disease Severity12
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Preface: Mass spectrometry in Alzheimer disease12
Fundamental Neurochemistry Review: Copper availability as a potential therapeutic target in progressive supranuclear palsy: Insight from other neurodegenerative diseases12
Gut microbiota modification by diosgenin mediates antiepileptic effects in a mouse model of epilepsy12
Genetically Confirmed Optimal Causal Association of Cerebrospinal Fluid Metabolites With Hemorrhagic Stroke12
Role of palmitoylation on the neuronal glycine transporter GlyT212
Misprogramming of glucose metabolism impairs recovery of hippocampal slices from neuronal GLT‐1 knockout mice and contributes to excitotoxic injury through mitochondrial superoxide production11
Butyrylcholinesterase in lipid metabolism: A new outlook11
Cannabis use, abuse, and withdrawal: Cannabinergic mechanisms, clinical, and preclinical findings11
ESN‐YSLA11
Issue Information11
Inhibition of CD38 and supplementation of nicotinamide riboside ameliorate lipopolysaccharide‐induced microglial and astrocytic neuroinflammation by increasing NAD+11
Fundamental Neurochemistry Review: The role of enteroendocrine cells in visceral pain11
Phospholipid cofactor solubilization inhibits formation of native prions11
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Spontaneous, transient adenosine release is not enhanced in the CA1 region of hippocampus during severe ischemia models11
Critical period of exposure to mercury and the diagnostic of autism spectrum disorder: A systematic review11
Biological and methodological complexities of beta‐amyloid peptide: Implications for Alzheimer’s disease research11
CXCR2 immunomodulatory therapy protects against microstructural white matter injury and gait abnormalities but does not mitigate deficits of cognition in a preclinical model of cerebral pal11
Lipid metabolism in dopaminergic neurons influences light entrainment11
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The causal role of circulating amino acids on neurodegenerative disorders: A two‐sample Mendelian randomization study10
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Quantitative proteomics of tau and Aβ in detergent fractions from Alzheimer's disease brains10
Chronic in vivo sequelae of repetitive acute mfb‐DBS on accumbal dopamine and midbrain neuronal activity10
Cell density impacts the susceptibility to ferroptosis by modulating IRP1‐mediated iron homeostasis10
Cannabidiol Protects Against Neurotoxic Reactive Astrocytes‐Induced Neuronal Death in Mouse Model of Epilepsy10
Zinc induces reactive astrogliosis through ERK‐dependent activation of Stat3 and promotes synaptic degeneration10
Relationships between gene expression and behavior in mice in response to systemic modulation of the O‐GlcNAcylation pathway10
The GTPase Rab21 is required for neuronal development and migration in the cerebral cortex10
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Molecular signatures from multi‐omics of autism spectrum disorders and schizophrenia10
The role of the neuronal microenvironment in sensory function and pain pathophysiology10
SARS‐CoV‐2, aging, and Post‐COVID‐19 neurodegeneration10
Bioisosteric analogs of MDMA: Improving the pharmacological profile?10
Oxidative Stress Suppresses Trk Signaling While Stimulating JNK‐Mediated Endocytosis and Cleavage of p75NTR: A Targetable Pathway for Neuroprotection in a Parkinson's 10
Plasma C18:0‐ceramide is a novel potential biomarker for disease severity in myasthenia gravis10
Disruption of amphetamine sensitization by alteration of dendritic thin spines in the nucleus accumbens core10
EXPRESSION OF CONCERN: Antioxidant Compounds Have Potent Anti‐fibrillogenic and Fibril‐destabilizing Effects for α‐synuclein Fibrils In Vitro10
Function and regulation of cis P‐tau in the pathogenesis and treatment of conventional and nonconventional tauopathies10
Wnt5a modulates dendritic spine dynamics through the regulation of Cofilin via small Rho GTPase activity in hippocampal neurons10
FMRP regulation of aggrecan mRNA translation controls perineuronal net development10
Mutant SOD1 aggregates formed in vitro and in cultured cells are polymorphic and differ from those arising in the CNS10
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Who's in, who's out? Re‐evaluation of lipid raft residents9
Issue Information9
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Cross‐species translational paradigms for assessing positive valence system as defined by the RDoC matrix9
Neurochemical correlates of synapse density in a Huntington's disease mouse model9
Effects of anti‐tau immunotherapy on reactive microgliosis, cerebral endotheliopathy, and cognitive function in an experimental model of cerebral malaria9
Translational validity of neuropsychological tasks of sustained attention between rodents and humans: A systematic review of three rodent tasks9
Dopamine transporter endocytic trafficking: Neuronal mechanisms and potential impact on DA‐dependent behaviors9
A common variant in the iron regulatory gene (Hfe) alters the metabolic and transcriptional landscape in brain regions vulnerable to neurodegeneration9
Dense dopaminergic innervation of the peri‐infarct cortex despite dopaminergic cell loss after a pure motor‐cortical stroke in rats9
Acknowledgement of reviewers9
Glucose as a carbon source to synthesize palmitate de novo in the adult rodent brain: Adding to the carbon recycling story in the brain9
Protein aggregation: A detrimental symptom or an adaptation mechanism?9
Neuropeptide CART modulates dopamine turnover in the nucleus accumbens: Insights into the anatomy of rewarding circuits9
Iron, ferroptosis, and ischemic stroke9
RETRACTION: The oxysterol 27‐hydroxycholesterol regulates α‐synuclein and tyrosine hydroxylase expression levels in human neuroblastoma cells through modulation of liver X receptors and estrogen recep9
Variant‐specific in vitro neuronal network phenotypes and drug sensitivity in SCN2A developmental and epileptic encephalopathy9
Retraction: Broad DNA repair responses in neural injury are associated with activation of the IL‐6 pathway in cholesterol‐fed rabbits9
Muscarinic signaling regulates voltage‐gated potassium channel KCNQ2 phosphorylation in the nucleus accumbens via protein kinase C for aversive learning9
SHSY5Y cells undergo changes in peroxisomal metabolism when exposed to decanoic acid9
Mitophagy suppresses motor neuron necroptotic mitochondrial damage and alleviates necroptosis that converges to SARM1 in acrylamide‐induced dying‐back neuropathy9
Loss of the parkinsonism‐associated protein FBXO7 in glutamatergic forebrain neurons in mice leads to abnormal motor behavior and synaptic defects9
Kynurenine pathway metabolites in cerebrospinal fluid and blood as potential biomarkers in Huntington's disease9
Single intracerebroventricular progranulin injection adversely affects the blood–brain barrier in experimental traumatic brain injury9
Copper induces neuron‐sparing, ferredoxin 1‐independent astrocyte toxicity mediated by oxidative stress9
Acknowledgements to reviewers9
Chemical traits of cerebral amyloid angiopathy in familial British‐, Danish‐, and non‐Alzheimerʼs dementias9
Exosomal miR‐142‐3p from M1‐polarized macrophages suppresses cell growth and immune escape in glioblastoma through regulating HMGB1‐mediated PD‐1/PD9
Brain energy metabolism: A roadmap for future research8
Regional and sex differences in spontaneous striatal dopamine transmission8
Associations of circulating metabolites with cerebral white matter hyperintensities8
Mechanisms of synapse‐to‐nucleus calcium signalling in striatal neurons and impairments in Huntington's disease8
Hyaluronan hydrates and compartmentalises the CNS/PNS extracellular matrix and provides niche environments conducive to the optimisation of neuronal activity8
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Acknowledgement of reviewers8
Amyloid‐β exposed astrocytes induce iron transport from endothelial cells at the blood–brain barrier by altering the ratio of apo‐ and holo‐transferrin8
Heme oxygenase‐1: The roles of both good and evil in neurodegenerative diseases8
METTL14 is decreased and regulates m6A modification of α‐synuclein in Parkinson's disease8
Plasma high‐density lipoprotein cargo is altered in Alzheimer's disease and is associated with regional brain volume8
Antagonists targeting eEF2 kinase rescue multiple aspects of pathophysiology in Alzheimer’s disease model mice8
Xanthurenic acid: A role in brain intercellular signaling8
Association of serum Gasdermin D with anti‐N‐methyl‐D‐aspartate receptor encephalitis8
The drebrin/EB3 pathway regulates cytoskeletal dynamics to drive neuritogenesis in embryonic cortical neurons8
NLRP3‐directed antisense oligonucleotides reduce microglial immunoactivities in vitro8
A natural small molecule‐mediated inhibition of alpha‐synuclein aggregation leads to neuroprotection in Caenorhabditis elegans8
Systemic inflammation induced the delayed reduction of excitatory synapses in the CA3 during ageing8
The Glutamate/GABA‐Glutamine Cycle: Insights, Updates, and Advances8
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Clear‐headed into old age: Resilience and resistance against brain aging—A PET imaging perspective8
Brain iron acquisition: An overview of homeostatic regulation and disease dysregulation8
The effects of KTKEGV repeat motif and intervening ATVA sequence on α‐synuclein solubility and assembly8
Editorial: Exciting developments in neurochemistry research and publishing8
Anti‐Prion Systems in Saccharomyces cerevisiae8
Muscle‐building supplement β‐hydroxy β‐methylbutyrate stimulates the maturation of oligodendroglial progenitor cells to oligodendrocytes8
Poly (I:C)‐induced maternal immune activation generates impairment of reversal learning performance in offspring8
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