Journal of Molecular and Cellular Cardiology

Papers
(The TQCC of Journal of Molecular and Cellular Cardiology is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-06-01 to 2024-06-01.)
ArticleCitations
p38 MAPK inhibition: A promising therapeutic approach for COVID-19197
SARS-CoV-2 receptor ACE2-dependent implications on the cardiovascular system: From basic science to clinical implications106
Clonal hematopoiesis of indeterminate potential (CHIP): Linking somatic mutations, hematopoiesis, chronic inflammation and cardiovascular disease93
MicroRNAs targeting the SARS-CoV-2 entry receptor ACE2 in cardiomyocytes83
HSF1 functions as a key defender against palmitic acid-induced ferroptosis in cardiomyocytes66
Gut microbiome - A potential mediator of pathogenesis in heart failure and its comorbidities: State-of-the-art review62
Longitudinal correlation of biomarkers of cardiac injury, inflammation, and coagulation to outcome in hospitalized COVID-19 patients62
Cardiac mechanisms of the beneficial effects of SGLT2 inhibitors in heart failure: Evidence for potential off-target effects57
Metformin protects against ischaemic myocardial injury by alleviating autophagy-ROS-NLRP3-mediated inflammatory response in macrophages56
BRD4 inhibition by JQ1 prevents high-fat diet-induced diabetic cardiomyopathy by activating PINK1/Parkin-mediated mitophagy in vivo54
Molecular nature and regulation of the mitochondrial permeability transition pore(s), drug target(s) in cardioprotection52
Targeting endothelial dysfunction and inflammation51
ATP synthase c-subunit ring as the channel of mitochondrial permeability transition: Regulator of metabolism in development and degeneration51
The role of autophagy in death of cardiomyocytes49
Under construction: The dynamic assembly, maintenance, and degradation of the cardiac sarcomere48
A 20/20 view of ANT function in mitochondrial biology and necrotic cell death48
Extracellular vesicular MicroRNA-27a* contributes to cardiac hypertrophy in chronic heart failure47
FNDC5/Irisin attenuates diabetic cardiomyopathy in a type 2 diabetes mouse model by activation of integrin αV/β5-AKT signaling and reduction of oxidative/nitrosative stress46
Isogenic models of hypertrophic cardiomyopathy unveil differential phenotypes and mechanism-driven therapeutics43
Coagulopathy in COVID-19: Focus on vascular thrombotic events43
Piezo1 is required for outflow tract and aortic valve development.42
Matters of the heart: Cellular sex differences42
Adenosine-to-inosine Alu RNA editing controls the stability of the pro-inflammatory long noncoding RNA NEAT1 in atherosclerotic cardiovascular disease42
Systematic transcriptomic and phenotypic characterization of human and murine cardiac myocyte cell lines and primary cardiomyocytes reveals serious limitations and low resemblances to adult cardiac ph42
Reconstructing the heart using iPSCs: Engineering strategies and applications40
Cardiomyocyte cell cycling, maturation, and growth by multinucleation in postnatal swine40
Exogenous IL-4 shuts off pro-inflammation in neutrophils while stimulating anti-inflammation in macrophages to induce neutrophil phagocytosis following myocardial infarction39
Reverse cardio-oncology: Exploring the effects of cardiovascular disease on cancer pathogenesis38
Mitochondrial permeability transition pore-dependent necrosis38
DCA-TGR5 signaling activation alleviates inflammatory response and improves cardiac function in myocardial infarction38
MyD88: At the heart of inflammatory signaling and cardiovascular disease38
Exosomes from adipose-derived stem cells alleviate myocardial infarction via microRNA-31/FIH1/HIF-1α pathway38
Programmed cell death in aortic aneurysm and dissection: A potential therapeutic target36
Organ-on-a-chip systems for vascular biology35
MITOL/MARCH5 determines the susceptibility of cardiomyocytes to doxorubicin-induced ferroptosis by regulating GSH homeostasis35
The debate continues – What is the role of MCU and mitochondrial calcium uptake in the heart?34
Endothelial contribution to COVID-19: an update on mechanisms and therapeutic implications34
Ferroptosis in heart failure33
Minimally invasive delivery of a hydrogel-based exosome patch to prevent heart failure33
Pharmacological inhibition of the mitochondrial Ca2+ uniporter: Relevance for pathophysiology and human therapy31
Acute effects of alcohol on cardiac electrophysiology and arrhythmogenesis: Insights from multiscale in silico analyses31
Mitochondrial protein hyperacetylation underpins heart failure with preserved ejection fraction in mice31
Piezo1 and BKCa channels in human atrial fibroblasts: Interplay and remodelling in atrial fibrillation30
Mitochondrial Ca2+ in heart failure: Not enough or too much?30
OxLDL-mediated immunologic memory in endothelial cells28
Sex- and age-specific regulation of ACE2: Insights into severe COVID-19 susceptibility28
Branched chain amino acids selectively promote cardiac growth at the end of the awake period28
What we know about cardiomyocyte dedifferentiation27
Pathogenesis of SARS-CoV-2 induced cardiac injury from the perspective of the virus27
MiR-144-5p limits experimental abdominal aortic aneurysm formation by mitigating M1 macrophage-associated inflammation: Suppression of TLR2 and OLR126
Calcium influx through the mitochondrial calcium uniporter holocomplex, MCUcx26
Cardiolipin deficiency elevates susceptibility to a lipotoxic hypertrophic cardiomyopathy26
Sex differences underlying preexisting cardiovascular disease and cardiovascular injury in COVID-1926
Cardiac injuries in coronavirus disease 2019 (COVID-19)25
An organ-on-a-chip model for pre-clinical drug evaluation in progressive non-genetic cardiomyopathy25
Function of histone methylation and acetylation modifiers in cardiac hypertrophy24
Mitochondrial Ca2+, redox environment and ROS emission in heart failure: Two sides of the same coin?24
Remodeling of the m6A landscape in the heart reveals few conserved post-transcriptional events underlying cardiomyocyte hypertrophy23
Apelin-potential therapy for COVID-19?23
Necroptosis in heart disease: Molecular mechanisms and therapeutic implications22
Targeting the population for gene therapy with MYBPC322
POPDC2 a novel susceptibility gene for conduction disorders22
How to repair a broken heart with pluripotent stem cell-derived cardiomyocytes21
The role of demethylases in cardiac development and disease21
Endothelin-1 is increased in the plasma of patients hospitalised with Covid-1921
Genes encoding ACE2, TMPRSS2 and related proteins mediating SARS-CoV-2 viral entry are upregulated with age in human cardiomyocytes20
Endothelial repair by stem and progenitor cells20
CircHelz activates NLRP3 inflammasome to promote myocardial injury by sponging miR-133a-3p in mouse ischemic heart20
Cyclic AMP represses pathological MEF2 activation by myocyte-specific hypo-phosphorylation of HDAC520
Krüppel-like factor (KLF)5: An emerging foe of cardiovascular health20
Increasing fatty acid oxidation elicits a sex-dependent response in failing mouse hearts20
Circadian influence on the microbiome improves heart failure outcomes19
Delineating chromatin accessibility re-patterning at single cell level during early stage of direct cardiac reprogramming19
Computational model of cardiomyocyte apoptosis identifies mechanisms of tyrosine kinase inhibitor-induced cardiotoxicity19
Nano-scale morphology of cardiomyocyte t-tubule/sarcoplasmic reticulum junctions revealed by ultra-rapid high-pressure freezing and electron tomography19
CaMKII exacerbates heart failure progression by activating class I HDACs19
Amino terminus of cardiac myosin binding protein-C regulates cardiac contractility19
Autotaxin inhibition reduces cardiac inflammation and mitigates adverse cardiac remodeling after myocardial infarction19
Early adaptive chromatin remodeling events precede pathologic phenotypes and are reinforced in the failing heart19
Heart failure impairs the mechanotransduction properties of human cardiac pericytes19
Circular RNA PVT1 silencing prevents ischemia-reperfusion injury in rat by targeting microRNA-125b and microRNA-200a19
B cells modulate the expression of MHC-II on cardiac CCR2− macrophages19
Myofilament glycation in diabetes reduces contractility by inhibiting tropomyosin movement, is rescued by cMyBPC domains19
Metabolic remodeling precedes mTORC1-mediated cardiac hypertrophy19
Glycogen synthase kinase-3β inhibition alleviates activation of the NLRP3 inflammasome in myocardial infarction18
Spatial N-glycomics of the human aortic valve in development and pediatric endstage congenital aortic valve stenosis18
Sarcoplasmic reticulum-mitochondria communication; implications for cardiac arrhythmia18
Integrins in cardiac fibrosis18
Suppression of canonical TGF-β signaling enables GATA4 to interact with H3K27me3 demethylase JMJD3 to promote cardiomyogenesis18
NAFLD as a continuous driver in the whole spectrum of vascular disease18
CYLD exaggerates pressure overload-induced cardiomyopathy via suppressing autolysosome efflux in cardiomyocytes18
Role of myeloid-derived chemokine CCL5/RANTES at an early stage of atherosclerosis18
Mechanisms underlying age-associated manifestation of cardiac sodium channel gain-of-function18
miR-564: A potential regulator of vascular smooth muscle cells and therapeutic target for aortic dissection18
Translational investigation of electrophysiology in hypertrophic cardiomyopathy17
Mcl-1-mediated mitochondrial fission protects against stress but impairs cardiac adaptation to exercise17
Quantitative analysis of variability in an integrated model of human ventricular electrophysiology and β-adrenergic signaling17
Current knowledge of pyroptosis in heart diseases17
β1-adrenergic receptor N-terminal cleavage by ADAM17; the mechanism for redox-dependent downregulation of cardiomyocyte β1-adrenergic receptors17
Enhanced NCLX-dependent mitochondrial Ca2+ efflux attenuates pathological remodeling in heart failure17
Production of functional cardiomyocytes and cardiac tissue from human induced pluripotent stem cells for regenerative therapy16
A directed network analysis of the cardiome identifies molecular pathways contributing to the development of HFpEF16
Glucose fluctuations promote vascular BK channels dysfunction via PKCα/NF-κB/MuRF1 signaling16
Targeting senescent cells for vascular aging and related diseases16
A roadmap for the characterization of energy metabolism in human cardiomyocytes derived from induced pluripotent stem cells16
Circulating microRNAs differentiate Kawasaki Disease from infectious febrile illnesses in childhood16
Beclin1 Haploinsufficiency accentuates second-hand smoke exposure -induced myocardial Remodeling and contractile dysfunction through a STING-mediated mechanism16
Exogenous extracellular matrix proteins decrease cardiac fibroblast activation in stiffening microenvironment through CAPG16
Updated and enhanced pig cardiac transcriptome based on long-read RNA sequencing and proteomics15
Cardiovascular disease and the biology of aging15
3D-cardiomics: A spatial transcriptional atlas of the mammalian heart15
Decreased inspired oxygen stimulates de novo formation of coronary collaterals in adult heart15
Diabetes changes gene expression but not DNA methylation in cardiac cells15
RBM20S639G mutation is a high genetic risk factor for premature death through RNA-protein condensates15
miR-374b-5p is increased in deep vein thrombosis and negatively targets IL-1015
Mep1a contributes to Ang II-induced cardiac remodeling by promoting cardiac hypertrophy, fibrosis and inflammation15
Dimethyl fumarate preserves left ventricular infarct integrity following myocardial infarction via modulation of cardiac macrophage and fibroblast oxidative metabolism15
Spen deficiency interferes with Connexin 43 expression and leads to heart failure in zebrafish14
5-Methoxytryptophan attenuates postinfarct cardiac injury by controlling oxidative stress and immune activation14
Downregulation of the zinc transporter SLC39A13 (ZIP13) is responsible for the activation of CaMKII at reperfusion and leads to myocardial ischemia/reperfusion injury in mouse hearts14
Soluble epoxide hydrolase deficiency attenuates lipotoxic cardiomyopathy via upregulation of AMPK-mTORC mediated autophagy14
Proteomic analysis of the cardiac myocyte secretome reveals extracellular protective functions for the ER stress response14
Nuclear-mitochondrial communication involving miR-181c plays an important role in cardiac dysfunction during obesity14
Hallmarks of exercised heart14
Impact of etiology on force and kinetics of left ventricular end-stage failing human myocardium14
Pathophysiology and pharmacological management of pulmonary and cardiovascular features of COVID-1913
Human engineered heart tissue transplantation in a guinea pig chronic injury model13
Advances in three-dimensional bioprinted stem cell-based tissue engineering for cardiovascular regeneration13
Global analysis of histone modifications and long-range chromatin interactions revealed the differential cistrome changes and novel transcriptional players in human dilated cardiomyopathy13
Inhibition of endoplasmic reticulum stress ameliorates cardiovascular injury in a rat model of metabolic syndrome13
BMP9 attenuates occurrence of venous malformation by maintaining endothelial quiescence and strengthening vessel walls via SMAD1/5/ID1/α-SMA pathway13
Glutamine uptake and catabolism is required for myofibroblast formation and persistence13
Phosphodiesterase type 4 anchoring regulates cAMP signaling to Popeye domain-containing proteins13
Triiodothyronine and dexamethasone alter potassium channel expression and promote electrophysiological maturation of human-induced pluripotent stem cell-derived cardiomyocytes13
Inhibiting microRNA-155 attenuates atrial fibrillation by targeting CACNA1C13
Engineering stem cell therapeutics for cardiac repair13
Proximity to injury, but neither number of nuclei nor ploidy define pathological adaptation and plasticity in cardiomyocytes13
MiR-185-5p regulates the development of myocardial fibrosis12
Sarcomere integrated biosensor detects myofilament-activating ligands in real time during twitch contractions in live cardiac muscle12
Amino acid differences between diabetic older adults and non-diabetic older adults and their associations with cardiovascular function12
Identifying modifier genes for hypertrophic cardiomyopathy12
Periostin-expressing Schwann cells and endoneurial cardiac fibroblasts contribute to sympathetic nerve fasciculation after birth12
High frequency of anti-DSG 2 antibodies in post COVID-19 serum samples12
Systems analysis of the mechanisms governing the cardiovascular response to changes in posture and in peripheral demand during exercise12
Three-dimensional chromatin organization in cardiac development and disease12
The effect of variable troponin C mutation thin filament incorporation on cardiac muscle twitch contractions12
Nestin represents a potential marker of pulmonary vascular remodeling in pulmonary arterial hypertension associated with congenital heart disease12
YAP1/TEAD1 upregulate platelet-derived growth factor receptor beta to promote vascular smooth muscle cell proliferation and neointima formation12
Computational modeling of aberrant electrical activity following remuscularization with intramyocardially injected pluripotent stem cell-derived cardiomyocytes12
Inhibition of Pyk2 and Src activity improves Cx43 gap junction intercellular communication12
MicroRNA-663 prevents monocrotaline-induced pulmonary arterial hypertension by targeting TGF-β1/smad2/3 signaling12
Type 2 innate lymphoid cells regulation by regulatory T cells attenuates atherosclerosis12
Pleiotropic cardiac functions controlled by ischemia-induced lncRNA H1912
Ion current profiles in canine ventricular myocytes obtained by the “onion peeling” technique11
Mitochondrial architecture in cardiac myocytes depends on cell shape and matrix rigidity11
Increased atrial effectiveness of flecainide conferred by altered biophysical properties of sodium channels11
Implications of the complex biology and micro-environment of cardiac sarcomeres in the use of high affinity troponin antibodies as serum biomarkers for cardiac disorders11
Ventricular SK2 upregulation following angiotensin II challenge: Modulation by p21-activated kinase-111
m6A methyltransferase METTL3 participated in sympathetic neural remodeling post-MI via the TRAF6/NF-κB pathway and ROS production11
Misoprostol attenuates neonatal cardiomyocyte proliferation through Bnip3, perinuclear calcium signaling, and inhibition of glycolysis11
The role of autophagic cell death in cardiac disease11
Eicosapentaenoic acid ameliorates pulmonary hypertension via inhibition of tyrosine kinase Fyn11
The selective RyR2 inhibitor ent-verticilide suppresses atrial fibrillation susceptibility caused by Pitx2 deficiency11
Upregulated hepatokine fetuin B aggravates myocardial ischemia/reperfusion injury through inhibiting insulin signaling in diabetic mice11
Conditional depletion of the acetyltransferase Tip60 protects against the damaging effects of myocardial infarction11
Genetics of cancer therapy-associated cardiotoxicity11
Enhancing fatty acid oxidation negatively regulates PPARs signaling in the heart11
Is MCU dispensable for normal heart function?11
The role of the PlGF/Flt-1 signaling pathway in the cardiorenal connection11
Adverse effects of hydroxychloroquine and azithromycin on contractility and arrhythmogenicity revealed by human engineered cardiac tissues11
Association with SERCA2a directs phospholamban trafficking to sarcoplasmic reticulum from a nuclear envelope pool11
IL4Rα signaling promotes neonatal cardiac regeneration and cardiomyocyte cell cycle activity11
Benefits in cardiac function by CD38 suppression: Improvement in NAD+ levels, exercise capacity, heart rate variability and protection against catecholamine-induced ventricular arrhythmias11
Regulatory T cells in ischemic cardiovascular injury and repair11
Generation of microRNA-378a-deficient hiPSC as a novel tool to study its role in human cardiomyocytes11
Txnip C247S mutation protects the heart against acute myocardial infarction11
Tissue-engineered vascular grafts and regeneration mechanisms11
Molecular determinants of pro-arrhythmia proclivity of d- and l-sotalol via a multi-scale modeling pipeline10
Bottom-up proteomic analysis of human adult cardiac tissue and isolated cardiomyocytes10
Systolic overload-induced pulmonary inflammation, fibrosis, oxidative stress and heart failure progression through interleukin-1β10
KMT2B-dependent RFK transcription activates the TNF-α/NOX2 pathway and enhances ferroptosis caused by myocardial ischemia-reperfusion10
Global identification of S-palmitoylated proteins and detection of palmitoylating (DHHC) enzymes in heart10
Comparing the effects of chemical Ca2+ dyes and R-GECO on contractility and Ca2+ transients in adult and human iPSC cardiomyocytes10
Clinical epigenomics for cardiovascular disease: Diagnostics and therapies10
Loss of Acta2 in cardiac fibroblasts does not prevent the myofibroblast differentiation or affect the cardiac repair after myocardial infarction10
Mutation location of HCM-causing troponin T mutations defines the degree of myofilament dysfunction in human cardiomyocytes10
Comprehensive evaluation of electrophysiological and 3D structural features of human atrial myocardium with insights on atrial fibrillation maintenance mechanisms10
Distinct mechanisms mediate pacemaker dysfunction associated with catecholaminergic polymorphic ventricular tachycardia mutations: Insights from computational modeling10
Zika virus induces myocardial immune response and myocarditis in mice10
Evidence that the acetyltransferase Tip60 induces the DNA damage response and cell-cycle arrest in neonatal cardiomyocytes10
NLRP3 inflammasome-driven IL-1β and IL-18 contribute to lipopolysaccharide-induced septic cardiomyopathy10
Validation of quantitative measure of repolarization reserve as a novel marker of drug induced proarrhythmia10
Methods of mouse cardiomyocyte isolation from postnatal heart10
Blocking endothelial TRPV4-Nox2 interaction helps reduce ROS production and inflammation, and improves vascular function in obese mice10
Quantitative proteomics characterization of acutely isolated primary adult rat cardiomyocytes and fibroblasts10
Combined high-throughput library screening and next generation RNA sequencing uncover microRNAs controlling human cardiac fibroblast biology10
GALNT4 primes monocytes adhesion and transmigration by regulating O-Glycosylation of PSGL-1 in atherosclerosis10
Phosphorylation of Troponin I finely controls the positioning of Troponin for the optimal regulation of cardiac muscle contraction10
Creld1 regulates myocardial development and function10
Epigenetic alterations of TGFβ and its main canonical signaling mediators in the context of cardiac fibrosis9
Smooth muscle cell CYB5R3 preserves cardiac and vascular function under chronic hypoxic stress9
Mapping genetic changes in the cAMP-signaling cascade in human atria9
Adaptation to exercise-induced stress is not dependent on cardiomyocyte α1A-adrenergic receptors9
Protective role of ErbB3 signaling in myeloid cells during adaptation to cardiac pressure overload9
Pharmacological and cell-specific genetic PI3Kα inhibition worsens cardiac remodeling after myocardial infarction9
A peptide of the amino-terminus of GRK2 induces hypertrophy and yet elicits cardioprotection after pressure overload9
Diverging consequences of hexosamine biosynthesis in cardiovascular disease9
Relevance of N6-methyladenosine regulators for transcriptome: Implications for development and the cardiovascular system9
Human epicardium-derived cells reinforce cardiac sympathetic innervation9
Phosphoproteomics of the developing heart identifies PERM1 - An outer mitochondrial membrane protein9
Exercise training reveals micro-RNAs associated with improved cardiac function and electrophysiology in rats with heart failure after myocardial infarction9
Considerations for using isolated cell systems to understand cardiac metabolism and biology9
Hippo/yes-associated protein signaling functions as a mechanotransducer in regulating vascular homeostasis9
Genetic and functional analyses of TBX4 reveal novel mechanisms underlying pulmonary arterial hypertension9
Engineering the aortic valve extracellular matrix through stages of development, aging, and disease9
Synergistic FRET assays for drug discovery targeting RyR2 channels9
Contribution of estrogen to the pregnancy-induced increase in cardiac automaticity9
The role of β-adrenergic system remodeling in human heart failure: A mechanistic investigation9
Differential effects of Smad2 and Smad3 in regulation of macrophage phenotype and function in the infarcted myocardium9
Prostaglandin D2 signaling and cardiovascular homeostasis9
A distinct molecular mechanism by which phenytoin rescues a novel long QT 3 variant9
Computation-assisted targeted proteomics of alternative splicing protein isoforms in the human heart9
With a grain of salt: Sodium elevation and metabolic remodelling in heart failure9
Intracoronary transplantation of pluripotent stem cell-derived cardiomyocytes: Inefficient procedure for cardiac regeneration9
ILF3 is responsible for hyperlipidemia-induced arteriosclerotic calcification by mediating BMP2 and STAT1 transcription9
Bone marrow- or adipose-mesenchymal stromal cell secretome preserves myocardial transcriptome profile and ameliorates cardiac damage following ex vivo cold storage9
The heart of cardiac reprogramming: The cardiac fibroblasts8
Triiodothyronine maintains cardiac transverse-tubule structure and function8
FBXW5 acts as a negative regulator of pathological cardiac hypertrophy by decreasing the TAK1 signaling to pro-hypertrophic members of the MAPK signaling pathway8
MicroRNA-21 regulates right ventricular remodeling secondary to pulmonary arterial pressure overload8
Direct proteomic and high-resolution microscopy biopsy analysis identifies distinct ventricular fates in severe aortic stenosis8
The harder the climb the better the view: The impact of substrate stiffness on cardiomyocyte fate8
Cardiac energy metabolism may play a fundamental role in congenital diaphragmatic hernia-associated ventricular dysfunction8
Suppression of myeloid YAP antagonizes adverse cardiac remodeling during pressure overload stress8
Blockade of sodium‑calcium exchanger via ORM-10962 attenuates cardiac alternans8
Computational model of brain endothelial cell signaling pathways predicts therapeutic targets for cerebral pathologies8
Computational modeling of mitochondrial K+- and H+-driven ATP synthesis8
GRK2 in cardiovascular disease and its potential as a therapeutic target8
Dexamethasone inhibits regeneration and causes ventricular aneurysm in the neonatal porcine heart after myocardial infarction8
Induction of GLI1 by miR-27b-3p/FBXW7/KLF5 pathway contributes to pulmonary arterial hypertension8
Inhibition of endoplasmic reticulum stress mediates the ameliorative effect of apelin on vascular calcification8
Dual role of miR-1 in the development and function of sinoatrial cells8
DELE1 is protective for mitochondrial cardiomyopathy8
Rad-GTPase contributes to heart rate via L-type calcium channel regulation8
Evidence for synergy between sarcomeres and fibroblasts in an in vitro model of myocardial reverse remodeling8
Identifying functional non-coding variants in APOA5/A4/C3/A1 gene cluster associated with coronary heart disease8
Microtubule polymerization state and clathrin-dependent internalization regulate dynamics of cardiac potassium channel8
Nuclear receptor Nur77 protects against oxidative stress by maintaining mitochondrial homeostasis via regulating mitochondrial fission and mitophagy in smooth muscle cell8
CineCT platform for in vivo and ex vivo measurement of 3D high resolution Lagrangian strains in the left ventricle following myocardial infarction and intramyocardial delivery of theranostic hydrogel7
Prostaglandin E1 attenuates AngII-induced cardiac hypertrophy via EP3 receptor activation and Netrin-1upregulation7
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