Journal of Molecular and Cellular Cardiology

Papers
(The TQCC of Journal of Molecular and Cellular Cardiology is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
Clonal hematopoiesis of indeterminate potential (CHIP): Linking somatic mutations, hematopoiesis, chronic inflammation and cardiovascular disease117
MicroRNAs targeting the SARS-CoV-2 entry receptor ACE2 in cardiomyocytes87
HSF1 functions as a key defender against palmitic acid-induced ferroptosis in cardiomyocytes72
Cardiac mechanisms of the beneficial effects of SGLT2 inhibitors in heart failure: Evidence for potential off-target effects71
Gut microbiome - A potential mediator of pathogenesis in heart failure and its comorbidities: State-of-the-art review65
Targeting endothelial dysfunction and inflammation61
The role of autophagy in death of cardiomyocytes57
Under construction: The dynamic assembly, maintenance, and degradation of the cardiac sarcomere57
BRD4 inhibition by JQ1 prevents high-fat diet-induced diabetic cardiomyopathy by activating PINK1/Parkin-mediated mitophagy in vivo57
FNDC5/Irisin attenuates diabetic cardiomyopathy in a type 2 diabetes mouse model by activation of integrin αV/β5-AKT signaling and reduction of oxidative/nitrosative stress55
Mitochondrial permeability transition pore-dependent necrosis53
Organ-on-a-chip systems for vascular biology49
Systematic transcriptomic and phenotypic characterization of human and murine cardiac myocyte cell lines and primary cardiomyocytes reveals serious limitations and low resemblances to adult cardiac ph48
Matters of the heart: Cellular sex differences47
Reconstructing the heart using iPSCs: Engineering strategies and applications47
Programmed cell death in aortic aneurysm and dissection: A potential therapeutic target45
Adenosine-to-inosine Alu RNA editing controls the stability of the pro-inflammatory long noncoding RNA NEAT1 in atherosclerotic cardiovascular disease44
MyD88: At the heart of inflammatory signaling and cardiovascular disease43
Ferroptosis in heart failure43
Exosomes from adipose-derived stem cells alleviate myocardial infarction via microRNA-31/FIH1/HIF-1α pathway42
MITOL/MARCH5 determines the susceptibility of cardiomyocytes to doxorubicin-induced ferroptosis by regulating GSH homeostasis41
Reverse cardio-oncology: Exploring the effects of cardiovascular disease on cancer pathogenesis40
Endothelial contribution to COVID-19: an update on mechanisms and therapeutic implications39
DCA-TGR5 signaling activation alleviates inflammatory response and improves cardiac function in myocardial infarction39
Piezo1 and BKCa channels in human atrial fibroblasts: Interplay and remodelling in atrial fibrillation36
Mitochondrial protein hyperacetylation underpins heart failure with preserved ejection fraction in mice35
Minimally invasive delivery of a hydrogel-based exosome patch to prevent heart failure35
Pharmacological inhibition of the mitochondrial Ca2+ uniporter: Relevance for pathophysiology and human therapy34
Mitochondrial Ca2+ in heart failure: Not enough or too much?32
Branched chain amino acids selectively promote cardiac growth at the end of the awake period32
Calcium influx through the mitochondrial calcium uniporter holocomplex, MCUcx31
An organ-on-a-chip model for pre-clinical drug evaluation in progressive non-genetic cardiomyopathy31
What we know about cardiomyocyte dedifferentiation31
Sex- and age-specific regulation of ACE2: Insights into severe COVID-19 susceptibility31
Endothelin-1 is increased in the plasma of patients hospitalised with Covid-1927
CircHelz activates NLRP3 inflammasome to promote myocardial injury by sponging miR-133a-3p in mouse ischemic heart27
The role of demethylases in cardiac development and disease26
How to repair a broken heart with pluripotent stem cell-derived cardiomyocytes26
Sex differences underlying preexisting cardiovascular disease and cardiovascular injury in COVID-1926
Mitochondrial Ca2+, redox environment and ROS emission in heart failure: Two sides of the same coin?26
Necroptosis in heart disease: Molecular mechanisms and therapeutic implications26
Remodeling of the m6A landscape in the heart reveals few conserved post-transcriptional events underlying cardiomyocyte hypertrophy25
Function of histone methylation and acetylation modifiers in cardiac hypertrophy25
Circular RNA PVT1 silencing prevents ischemia-reperfusion injury in rat by targeting microRNA-125b and microRNA-200a24
Krüppel-like factor (KLF)5: An emerging foe of cardiovascular health23
Targeting the population for gene therapy with MYBPC323
Integrins in cardiac fibrosis23
Increasing fatty acid oxidation elicits a sex-dependent response in failing mouse hearts23
Myofilament glycation in diabetes reduces contractility by inhibiting tropomyosin movement, is rescued by cMyBPC domains22
Role of myeloid-derived chemokine CCL5/RANTES at an early stage of atherosclerosis21
Endothelial repair by stem and progenitor cells21
B cells modulate the expression of MHC-II on cardiac CCR2− macrophages21
Nano-scale morphology of cardiomyocyte t-tubule/sarcoplasmic reticulum junctions revealed by ultra-rapid high-pressure freezing and electron tomography21
NAFLD as a continuous driver in the whole spectrum of vascular disease21
Autotaxin inhibition reduces cardiac inflammation and mitigates adverse cardiac remodeling after myocardial infarction21
Metabolic remodeling precedes mTORC1-mediated cardiac hypertrophy21
Dimethyl fumarate preserves left ventricular infarct integrity following myocardial infarction via modulation of cardiac macrophage and fibroblast oxidative metabolism21
Translational investigation of electrophysiology in hypertrophic cardiomyopathy21
Cardiovascular disease and the biology of aging20
Circadian influence on the microbiome improves heart failure outcomes20
Delineating chromatin accessibility re-patterning at single cell level during early stage of direct cardiac reprogramming20
Computational model of cardiomyocyte apoptosis identifies mechanisms of tyrosine kinase inhibitor-induced cardiotoxicity20
Heart failure impairs the mechanotransduction properties of human cardiac pericytes20
miR-564: A potential regulator of vascular smooth muscle cells and therapeutic target for aortic dissection20
Spatial N-glycomics of the human aortic valve in development and pediatric endstage congenital aortic valve stenosis20
Mechanisms underlying age-associated manifestation of cardiac sodium channel gain-of-function20
Sarcoplasmic reticulum-mitochondria communication; implications for cardiac arrhythmia20
Production of functional cardiomyocytes and cardiac tissue from human induced pluripotent stem cells for regenerative therapy19
Early adaptive chromatin remodeling events precede pathologic phenotypes and are reinforced in the failing heart19
Glycogen synthase kinase-3β inhibition alleviates activation of the NLRP3 inflammasome in myocardial infarction19
β1-adrenergic receptor N-terminal cleavage by ADAM17; the mechanism for redox-dependent downregulation of cardiomyocyte β1-adrenergic receptors19
Amino terminus of cardiac myosin binding protein-C regulates cardiac contractility19
Diabetes changes gene expression but not DNA methylation in cardiac cells19
CaMKII exacerbates heart failure progression by activating class I HDACs19
Current knowledge of pyroptosis in heart diseases19
Enhanced NCLX-dependent mitochondrial Ca2+ efflux attenuates pathological remodeling in heart failure18
Suppression of canonical TGF-β signaling enables GATA4 to interact with H3K27me3 demethylase JMJD3 to promote cardiomyogenesis18
Hallmarks of exercised heart18
NLRP3 inflammasome-driven IL-1β and IL-18 contribute to lipopolysaccharide-induced septic cardiomyopathy17
Glutamine uptake and catabolism is required for myofibroblast formation and persistence17
3D-cardiomics: A spatial transcriptional atlas of the mammalian heart17
Human engineered heart tissue transplantation in a guinea pig chronic injury model17
Targeting senescent cells for vascular aging and related diseases17
A roadmap for the characterization of energy metabolism in human cardiomyocytes derived from induced pluripotent stem cells17
Decreased inspired oxygen stimulates de novo formation of coronary collaterals in adult heart16
Soluble epoxide hydrolase deficiency attenuates lipotoxic cardiomyopathy via upregulation of AMPK-mTORC mediated autophagy16
Beclin1 Haploinsufficiency accentuates second-hand smoke exposure -induced myocardial Remodeling and contractile dysfunction through a STING-mediated mechanism16
YAP1/TEAD1 upregulate platelet-derived growth factor receptor beta to promote vascular smooth muscle cell proliferation and neointima formation16
Exogenous extracellular matrix proteins decrease cardiac fibroblast activation in stiffening microenvironment through CAPG16
Downregulation of the zinc transporter SLC39A13 (ZIP13) is responsible for the activation of CaMKII at reperfusion and leads to myocardial ischemia/reperfusion injury in mouse hearts15
Spen deficiency interferes with Connexin 43 expression and leads to heart failure in zebrafish15
Genetics of cancer therapy-associated cardiotoxicity15
Updated and enhanced pig cardiac transcriptome based on long-read RNA sequencing and proteomics15
Mep1a contributes to Ang II-induced cardiac remodeling by promoting cardiac hypertrophy, fibrosis and inflammation15
The effect of variable troponin C mutation thin filament incorporation on cardiac muscle twitch contractions15
RBM20S639G mutation is a high genetic risk factor for premature death through RNA-protein condensates15
Phosphodiesterase type 4 anchoring regulates cAMP signaling to Popeye domain-containing proteins15
KMT2B-dependent RFK transcription activates the TNF-α/NOX2 pathway and enhances ferroptosis caused by myocardial ischemia-reperfusion15
Mitochondrial architecture in cardiac myocytes depends on cell shape and matrix rigidity15
Loss of Acta2 in cardiac fibroblasts does not prevent the myofibroblast differentiation or affect the cardiac repair after myocardial infarction15
Impact of etiology on force and kinetics of left ventricular end-stage failing human myocardium15
The role of autophagic cell death in cardiac disease14
The selective RyR2 inhibitor ent-verticilide suppresses atrial fibrillation susceptibility caused by Pitx2 deficiency14
High frequency of anti-DSG 2 antibodies in post COVID-19 serum samples14
Systems analysis of the mechanisms governing the cardiovascular response to changes in posture and in peripheral demand during exercise14
Triiodothyronine and dexamethasone alter potassium channel expression and promote electrophysiological maturation of human-induced pluripotent stem cell-derived cardiomyocytes14
Inhibiting microRNA-155 attenuates atrial fibrillation by targeting CACNA1C14
m6A methyltransferase METTL3 participated in sympathetic neural remodeling post-MI via the TRAF6/NF-κB pathway and ROS production14
MicroRNA-663 prevents monocrotaline-induced pulmonary arterial hypertension by targeting TGF-β1/smad2/3 signaling14
5-Methoxytryptophan attenuates postinfarct cardiac injury by controlling oxidative stress and immune activation14
MiR-185-5p regulates the development of myocardial fibrosis14
Upregulated hepatokine fetuin B aggravates myocardial ischemia/reperfusion injury through inhibiting insulin signaling in diabetic mice13
Advances in three-dimensional bioprinted stem cell-based tissue engineering for cardiovascular regeneration13
Pathophysiology and pharmacological management of pulmonary and cardiovascular features of COVID-1913
Adverse effects of hydroxychloroquine and azithromycin on contractility and arrhythmogenicity revealed by human engineered cardiac tissues13
Clinical epigenomics for cardiovascular disease: Diagnostics and therapies13
Generation of microRNA-378a-deficient hiPSC as a novel tool to study its role in human cardiomyocytes13
Proximity to injury, but neither number of nuclei nor ploidy define pathological adaptation and plasticity in cardiomyocytes13
Tissue-engineered vascular grafts and regeneration mechanisms13
Three-dimensional chromatin organization in cardiac development and disease13
Benefits in cardiac function by CD38 suppression: Improvement in NAD+ levels, exercise capacity, heart rate variability and protection against catecholamine-induced ventricular arrhythmias13
Engineering stem cell therapeutics for cardiac repair13
Blocking endothelial TRPV4-Nox2 interaction helps reduce ROS production and inflammation, and improves vascular function in obese mice13
IL4Rα signaling promotes neonatal cardiac regeneration and cardiomyocyte cell cycle activity13
Ion current profiles in canine ventricular myocytes obtained by the “onion peeling” technique13
Periostin-expressing Schwann cells and endoneurial cardiac fibroblasts contribute to sympathetic nerve fasciculation after birth13
Amino acid differences between diabetic older adults and non-diabetic older adults and their associations with cardiovascular function12
The role of the PlGF/Flt-1 signaling pathway in the cardiorenal connection12
Epigenetic alterations of TGFβ and its main canonical signaling mediators in the context of cardiac fibrosis12
Direct proteomic and high-resolution microscopy biopsy analysis identifies distinct ventricular fates in severe aortic stenosis12
Differential effects of Smad2 and Smad3 in regulation of macrophage phenotype and function in the infarcted myocardium12
Inhibition of Pyk2 and Src activity improves Cx43 gap junction intercellular communication12
GALNT4 primes monocytes adhesion and transmigration by regulating O-Glycosylation of PSGL-1 in atherosclerosis12
Smooth muscle cell CYB5R3 preserves cardiac and vascular function under chronic hypoxic stress12
Mutation location of HCM-causing troponin T mutations defines the degree of myofilament dysfunction in human cardiomyocytes12
Computational modeling of aberrant electrical activity following remuscularization with intramyocardially injected pluripotent stem cell-derived cardiomyocytes12
Bone marrow- or adipose-mesenchymal stromal cell secretome preserves myocardial transcriptome profile and ameliorates cardiac damage following ex vivo cold storage12
Eicosapentaenoic acid ameliorates pulmonary hypertension via inhibition of tyrosine kinase Fyn12
Nestin represents a potential marker of pulmonary vascular remodeling in pulmonary arterial hypertension associated with congenital heart disease12
Conditional depletion of the acetyltransferase Tip60 protects against the damaging effects of myocardial infarction12
The role of β-adrenergic system remodeling in human heart failure: A mechanistic investigation11
Ventricular SK2 upregulation following angiotensin II challenge: Modulation by p21-activated kinase-111
Cardiac energy metabolism may play a fundamental role in congenital diaphragmatic hernia-associated ventricular dysfunction11
Global identification of S-palmitoylated proteins and detection of palmitoylating (DHHC) enzymes in heart11
Phosphorylation of Troponin I finely controls the positioning of Troponin for the optimal regulation of cardiac muscle contraction11
Increased atrial effectiveness of flecainide conferred by altered biophysical properties of sodium channels11
Molecular determinants of pro-arrhythmia proclivity of d- and l-sotalol via a multi-scale modeling pipeline11
Prostaglandin D2 signaling and cardiovascular homeostasis11
Txnip C247S mutation protects the heart against acute myocardial infarction11
ILF3 is responsible for hyperlipidemia-induced arteriosclerotic calcification by mediating BMP2 and STAT1 transcription11
EFHD1 ablation inhibits cardiac mitoflash activation and protects cardiomyocytes from ischemia11
Unlocking cardiomyocyte renewal potential for myocardial regeneration therapy11
YAP inhibition promotes endothelial cell differentiation from pluripotent stem cell through EC master transcription factor FLI111
Comprehensive evaluation of electrophysiological and 3D structural features of human atrial myocardium with insights on atrial fibrillation maintenance mechanisms11
Computation-assisted targeted proteomics of alternative splicing protein isoforms in the human heart11
Multi-omics analyses identify molecular signatures with prognostic values in different heart failure aetiologies11
Evidence that the acetyltransferase Tip60 induces the DNA damage response and cell-cycle arrest in neonatal cardiomyocytes11
Deficiency of cystathionine gamma-lyase promotes aortic elastolysis and medial degeneration in aged mice11
Zika virus induces myocardial immune response and myocarditis in mice10
Splicing factors in the heart: Uncovering shared and unique targets10
Creld1 regulates myocardial development and function10
Exercise training reveals micro-RNAs associated with improved cardiac function and electrophysiology in rats with heart failure after myocardial infarction10
Nuclear receptor Nur77 protects against oxidative stress by maintaining mitochondrial homeostasis via regulating mitochondrial fission and mitophagy in smooth muscle cell10
Pharmacological and cell-specific genetic PI3Kα inhibition worsens cardiac remodeling after myocardial infarction10
Engineering the aortic valve extracellular matrix through stages of development, aging, and disease10
A peptide of the amino-terminus of GRK2 induces hypertrophy and yet elicits cardioprotection after pressure overload10
Comparing the effects of chemical Ca2+ dyes and R-GECO on contractility and Ca2+ transients in adult and human iPSC cardiomyocytes10
Standardised method for cardiomyocyte isolation and purification from individual murine neonatal, infant, and adult hearts10
Methods of mouse cardiomyocyte isolation from postnatal heart10
Bottom-up proteomic analysis of human adult cardiac tissue and isolated cardiomyocytes10
Genetic and functional analyses of TBX4 reveal novel mechanisms underlying pulmonary arterial hypertension10
Combined high-throughput library screening and next generation RNA sequencing uncover microRNAs controlling human cardiac fibroblast biology10
Computational model of brain endothelial cell signaling pathways predicts therapeutic targets for cerebral pathologies10
Rad-GTPase contributes to heart rate via L-type calcium channel regulation10
Considerations for using isolated cell systems to understand cardiac metabolism and biology10
The harder the climb the better the view: The impact of substrate stiffness on cardiomyocyte fate10
With a grain of salt: Sodium elevation and metabolic remodelling in heart failure10
Intracoronary transplantation of pluripotent stem cell-derived cardiomyocytes: Inefficient procedure for cardiac regeneration10
microRNA neural networks improve diagnosis of acute coronary syndrome (ACS)9
Synergistic FRET assays for drug discovery targeting RyR2 channels9
Evidence for synergy between sarcomeres and fibroblasts in an in vitro model of myocardial reverse remodeling9
GRK2 in cardiovascular disease and its potential as a therapeutic target9
PPAR-δ: A key nuclear receptor in vascular function and remodeling9
Mapping genetic changes in the cAMP-signaling cascade in human atria9
CineCT platform for in vivo and ex vivo measurement of 3D high resolution Lagrangian strains in the left ventricle following myocardial infarction and intramyocardial delivery of theranostic hydrogel9
Inhibition of endoplasmic reticulum stress mediates the ameliorative effect of apelin on vascular calcification9
The heart of cardiac reprogramming: The cardiac fibroblasts9
Blockade of sodium‑calcium exchanger via ORM-10962 attenuates cardiac alternans9
Triiodothyronine maintains cardiac transverse-tubule structure and function9
Relevance of N6-methyladenosine regulators for transcriptome: Implications for development and the cardiovascular system9
Phosphoproteomics of the developing heart identifies PERM1 - An outer mitochondrial membrane protein9
Protective role of ErbB3 signaling in myeloid cells during adaptation to cardiac pressure overload9
Regulation of endogenous cardiomyocyte proliferation: The known unknowns9
Ythdf2 regulates cardiac remodeling through its mRNA target transcripts9
Improved epicardial cardiac fibroblast generation from iPSCs9
Dual role of miR-1 in the development and function of sinoatrial cells9
DELE1 is protective for mitochondrial cardiomyopathy9
Diverging consequences of hexosamine biosynthesis in cardiovascular disease9
Klf4 deficiency exacerbates myocardial ischemia/reperfusion injury in mice via enhancing ROCK1/DRP1 pathway-dependent mitochondrial fission9
MicroRNA-21 regulates right ventricular remodeling secondary to pulmonary arterial pressure overload9
Adaptation to exercise-induced stress is not dependent on cardiomyocyte α1A-adrenergic receptors9
Hippo/yes-associated protein signaling functions as a mechanotransducer in regulating vascular homeostasis9
Induction of GLI1 by miR-27b-3p/FBXW7/KLF5 pathway contributes to pulmonary arterial hypertension9
Coronary vessel formation in development and regeneration: origins and mechanisms8
Distinct effects of cardiac mitochondrial calcium uniporter inactivation via EMRE deletion in the short and long term8
Time series RNA-seq analysis identifies MAPK10 as a critical gene in diabetes mellitus-induced atrial fibrillation in mice8
Elevated EZH2 in ischemic heart disease epigenetically mediates suppression of NaV1.5 expression8
FBXW5 acts as a negative regulator of pathological cardiac hypertrophy by decreasing the TAK1 signaling to pro-hypertrophic members of the MAPK signaling pathway8
Xanthine oxidoreductase-mediated injury is amplified by upregulated AMP deaminase in type 2 diabetic rat hearts under the condition of pressure overload8
The cell-autonomous and non–cell-autonomous roles of the Hippo pathway in heart regeneration8
Suppression of myeloid YAP antagonizes adverse cardiac remodeling during pressure overload stress8
Deficiency of proline/serine-rich coiled-coil protein 1 (PSRC1) accelerates trimethylamine N-oxide-induced atherosclerosis in ApoE−/− mice8
Targeting immunoregulation for cardiac regeneration8
Inhibition of sphingomyelinase attenuates diet – Induced increases in aortic stiffness8
Identification of a novel cardiac epitope triggering T-cell responses in patients with myocardial infarction8
Regulation of extracellular matrix composition by fibroblasts during perinatal cardiac maturation8
Oxidized LDL but not angiotensin II induces cardiomyocyte hypertrophic responses through the interaction between LOX-1 and AT1 receptors8
Computational modeling of mitochondrial K+- and H+-driven ATP synthesis8
Protein acetylation in cardiac aging8
Human cardiac myosin-binding protein C phosphorylation- and mutation-dependent structural dynamics monitored by time-resolved FRET7
Direct coculture of human pluripotent stem cell-derived cardiac progenitor cells with epicardial cells induces cardiomyocyte proliferation and reduces sarcomere organization7
PGE2 protects against heart failure through inhibiting TGF-β1 synthesis in cardiomyocytes and crosstalk between TGF-β1 and GRK27
Insights on aortic aneurysm and dissection: Role of the extracellular environment in vascular homeostasis7
A junctional cAMP compartment regulates rapid Ca2+ signaling in atrial myocytes7
In vivo deep network tracing reveals phosphofructokinase-mediated coordination of biosynthetic pathway activity in the myocardium7
Prostaglandin E1 attenuates AngII-induced cardiac hypertrophy via EP3 receptor activation and Netrin-1upregulation7
Partial and complete loss of myosin binding protein H-like cause cardiac conduction defects7
Aldo-keto reductase family 1 member B induces aortic valve calcification by activating hippo signaling in valvular interstitial cells7
CXCR4 blockade in macrophage promotes angiogenesis in ischemic hindlimb by modulating autophagy7
Preserved cardiac performance and adrenergic response in a rabbit model with decreased ryanodine receptor 2 expression7
Hypoxia signaling and oxygen metabolism in cardio-oncology7
Computational modeling approaches to cAMP/PKA signaling in cardiomyocytes7
Stabilin-1 mediates beneficial monocyte recruitment and tolerogenic macrophage programming during CVB3-induced viral myocarditis7
Multilayer control of cardiac electrophysiology by microRNAs7
Can polarization of macrophage metabolism enhance cardiac regeneration?7
Individual variability in animal-specific hemodynamic compensation following myocardial infarction7
Systemic iron deficiency does not affect the cardiac iron content and progression of heart failure7
Epigallocatechin gallate facilitates extracellular elastin fiber formation in induced pluripotent stem cell derived vascular smooth muscle cells for tissue engineering7
Cellular reprogramming of fibroblasts in heart regeneration7
MNK2-eIF4E axis promotes cardiac repair in the infarcted mouse heart by activating cyclin D17
A novel transcription factor combination for direct reprogramming to a spontaneously contracting human cardiomyocyte-like state7
RyR2 inhibition with dantrolene is antiarrhythmic, prevents further pathological remodeling, and improves cardiac function in chronic ischemic heart disease7
Distinct effects of intracellular vs. extracellular acidic pH on the cardiac metabolome during ischemia and reperfusion7
E-cigarette exposure with or without heating the e-liquid induces differential remodeling in the lungs and right heart of mice7
Drp1/p53 interaction mediates p53 mitochondrial localization and dysfunction in septic cardiomyopathy6
Molecular remodeling of Cx43, but not structural remodeling, promotes arrhythmias in an arrhythmogenic canine model of nonischemic heart failure6
Reading the heart at single-cell resolution6
ICAM-1-related noncoding RNA accelerates atherosclerosis by amplifying NF-κB signaling6
Signaling network model of cardiomyocyte morphological changes in familial cardiomyopathy6
Cardiac epigenetics: Driving signals to the cardiac epigenome in development and disease6
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