Journal of Lipid Research

Article	Citations
Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures	461
Recommendations for good practice in MS-based lipidomics	109
The foundations and development of lipidomics	91
Novel method for quantification of lipoprotein(a)-cholesterol: implications for improving accuracy of LDL-C measurements	76
Biogeography of microbial bile acid transformations along the murine gut	73
Clinical lipidomics: realizing the potential of lipid profiling	68
Role and mechanism of the action of angiopoietin-like protein ANGPTL4 in plasma lipid metabolism	66
Lipid metabolism dysregulation in diabetic retinopathy	60
Fatty acid oxidation and photoreceptor metabolic needs	58
The roles of lipids in SARS-CoV-2 viral replication and the host immune response	56
ApoA5 lowers triglyceride levels via suppression of ANGPTL3/8-mediated LPL inhibition	51
Association of serum HDL-cholesterol and apolipoprotein A1 levels with risk of severe SARS-CoV-2 infection	50
Accurate quantification of lipid species affected by isobaric overlap in Fourier-transform mass spectrometry	47
Nonalcoholic fatty liver disease stratification by liver lipidomics	47
Whole picture of human stratum corneum ceramides, including the chain-length diversity of long-chain bases	46
Hepatic deletion of Mboat7 (LPIAT1) causes activation of SREBP-1c and fatty liver	45
Retinoids in the visual cycle: role of the retinal G protein-coupled receptor	43
Sphingolipids as critical players in retinal physiology and pathology	43
Very long chain fatty acid-containing lipids: a decade of novel insights from the study of ELOVL4	43
Distinct biological activities of isomers from several families of branched fatty acid esters of hydroxy fatty acids (FAHFAs)	41
EPA and DHA containing phospholipids have contrasting effects on membrane structure	39
Deep-lipidotyping by mass spectrometry: recent technical advances and applications	39
The lipid biology of sepsis	37
Lipid and metabolic syndrome traits in coronary artery disease: a Mendelian randomization study	36
Omega-3 versus Omega-6 fatty acid availability is controlled by hydrophobic site geometries of phospholipase A2s	36

Cholesterol metabolism: from lipidomics to immunology	36
The PCSK9 discovery, an inactive protease with varied functions in hypercholesterolemia, viral infections, and cancer	35
Insulin resistance dysregulates CYP7B1 leading to oxysterol accumulation: a pathway for NAFL to NASH transition	34
Cholesterol homeostasis in the vertebrate retina: biology and pathobiology	34
The SARS-CoV2 envelope differs from host cells, exposes procoagulant lipids, and is disrupted in vivo by oral rinses	34
The SGLT2 inhibitor dapagliflozin promotes systemic FFA mobilization, enhances hepatic β-oxidation, and induces ketosis	33
Lipoprotein metabolism in familial hypercholesterolemia	32
β-Carotene conversion to vitamin A delays atherosclerosis progression by decreasing hepatic lipid secretion in mice	32
Dietary sphinganine is selectively assimilated by members of the mammalian gut microbiome	32
SCD1 promotes lipid mobilization in subcutaneous white adipose tissue	31
The bidirectional link between HDL and COVID-19 infections	31
Lipid droplet-mitochondria coupling via perilipin 5 augments respiratory capacity but is dispensable for FA oxidation	30
Carboxylesterase 2 proteins are efficient diglyceride and monoglyceride lipases possibly implicated in metabolic disease	30
Evaluation of the available cholesterol concentration in the inner leaflet of the plasma membrane of mammalian cells	28
Lipid signature of advanced human carotid atherosclerosis assessed by mass spectrometry imaging	28
An anti-ANGPTL3/8 antibody decreases circulating triglycerides by binding to a LPL-inhibitory leucine zipper-like motif	28
Sorting through the extensive and confusing roles of sortilin in metabolic disease	28
Lipid conformational order and the etiology of cataract and dry eye	28
Shark liver oil supplementation enriches endogenous plasmalogens and reduces markers of dyslipidemia and inflammation	27
LDL-C calculated by Friedewald, Martin-Hopkins, or NIH equation 2 versus beta-quantification: pooled alirocumab trials	27
The emerging roles of the macular pigment carotenoids throughout the lifespan and in prenatal supplementation	27
Membrane cholesterol regulates TRPV4 function, cytoskeletal expression, and the cellular response to tension	27
Harmonized procedures lead to comparable quantification of total oxylipins across laboratories	27
Lipidomic and transcriptional analysis of the linoleoyl-omega-hydroxyceramide biosynthetic pathway in human psoriatic lesions	27
The anti-tubercular activity of simvastatin is mediated by cholesterol-driven autophagy via the AMPK-mTORC1-TFEB axis	26
Existing and emerging therapies for the treatment of familial hypercholesterolemia	26
Docosanoid signaling modulates corneal nerve regeneration: effect on tear secretion, wound healing, and neuropathic pain	25
Plasma ceramides containing saturated fatty acids are associated with risk of type 2 diabetes	25
Chylomicronemia from GPIHBP1 autoantibodies	25
The maternal blood lipidome is indicative of the pathogenesis of severe preeclampsia	25
Bisretinoid phospholipid and vitamin A aldehyde: shining a light	25
Perilipin 5 S155 phosphorylation by PKA is required for the control of hepatic lipid metabolism and glycemic control	24
Determination of tissue contributions to the circulating lipid pool in cold exposure via systematic assessment of lipid profiles	24
Suppressing postcollection lysophosphatidic acid metabolism improves the precision of plasma LPA quantification	23
Atherosclerosis-associated hepatic secretion of VLDL but not PCSK9 is dependent on cargo receptor protein Surf4	23
Plin2 deletion increases cholesteryl ester lipid droplet content and disturbs cholesterol balance in adrenal cortex	22
A novel phosphoglycerol serine-glycine lipodipeptide of Porphyromonas gingivalis is a TLR2 ligand	22
LRAT coordinates the negative-feedback regulation of intestinal retinoid biosynthesis from β-carotene	22
Angiopoietin-like 3 inhibition of endothelial lipase is not modulated by angiopoietin-like 8	22
Fatty acyl availability modulates cardiolipin composition and alters mitochondrial function in HeLa cells	22
CRISPR/Cas9 deletion of ORMDLs reveals complexity in sphingolipid metabolism	21
Skin fibroblast metabolomic profiling reveals that lipid dysfunction predicts the severity of Friedreich’s ataxia	21
Genetic testing for familial hypercholesterolemia—past, present, and future	21
From NAFLD to MASLD: updated naming and diagnosis criteria for fatty liver disease	21
Cholesterol transport between red blood cells and lipoproteins contributes to cholesterol metabolism in blood	21
Progression of chronic kidney disease in familial LCAT deficiency: a follow-up of the Italian cohort	20
Inhibition of lysosomal phospholipase A2 predicts drug-induced phospholipidosis	20
A liquid chromatography-mass spectrometry workflow for in-depth quantitation of fatty acid double bond location isomers	19
The role of full-length apoE in clearance of Gram-negative bacteria and their endotoxins	19
The lipidome in nonalcoholic fatty liver disease: actionable targets	19

Regulation of astrocyte lipid metabolism and ApoE secretion by the microglial oxysterol, 25-hydroxycholesterol	19
Overview of how N32 and N34 elovanoids sustain sight by protecting retinal pigment epithelial cells and photoreceptors	19
Nuclear translocation ability of Lipin differentially affects gene expression and survival in fed and fasting Drosophila	19
Metabolic profiling in serum, cerebrospinal fluid, and brain of patients with cerebrotendinous xanthomatosis	18
Membrane-bound O-acyltransferase 7 (MBOAT7)-driven phosphatidylinositol remodeling in advanced liver disease	18
Distinctive sphingolipid patterns in chronic multiple sclerosis lesions	18
The ligand-bound state of a G protein-coupled receptor stabilizes the interaction of functional cholesterol molecules	17
Altered HDL proteome predicts incident CVD in chronic kidney disease patients	17
Characterization of essential domains in HSD17B13 for cellular localization and enzymatic activity	17
Sar1b mutant mice recapitulate gastrointestinal abnormalities associated with chylomicron retention disease	17
Octanoate is differentially metabolized in liver and muscle and fails to rescue cardiomyopathy in CPT2 deficiency	17
25-Hydroxycholesterol 3-sulfate is an endogenous ligand of DNA methyltransferases in hepatocytes	17
Membrane-bound sn-1,2-diacylglycerols explain the dissociation of hepatic insulin resistance from hepatic steatosis in MTTP knockout mice	16
Phytosphingosine ceramide mainly localizes in the central layer of the unique lamellar phase of skin lipid model systems	16
Ceramide kinase regulates acute wound healing by suppressing 5-oxo-ETE biosynthesis and signaling via its receptor OXER1	16
Hsa-miRNA-23a-3p promotes atherogenesis in a novel mouse model of atherosclerosis	16
Bioavailability and spatial distribution of fatty acids in the rat retina after dietary omega-3 supplementation	15
Impact of vitamin A transport and storage on intestinal retinoid homeostasis and functions	15
Brown adipose tissue lipoprotein and glucose disposal is not determined by thermogenesis in uncoupling protein 1-deficient mice	15
The role of lipid second messengers in aldosterone synthesis and secretion	15
The Hylemon-Björkhem pathway of bile acid 7-dehydroxylation: history, biochemistry, and microbiology	15
Pregnancy is accompanied by larger high density lipoprotein particles and compositionally distinct subspecies	15
High-fat diet activates liver iPLA2γ generating eicosanoids that mediate metabolic stress	15
ATP-binding cassette transporters mediate differential biosynthesis of glycosphingolipid species	15
Differential contributions of choline phosphotransferases CPT1 and CEPT1 to the biosynthesis of choline phospholipids	15
PEGylated AdipoRon derivatives improve glucose and lipid metabolism under insulinopenic and high-fat diet conditions	15
Myc linked to dysregulation of cholesterol transport and storage in nonsmall cell lung cancer	15
Palmitoylation of acetylated tubulin and association with ceramide-rich platforms is critical for ciliogenesis	15
High density lipoprotein-associated miRNA is increased following Roux-en-Y gastric bypass surgery for severe obesity	14
Depletion of essential isoprenoids and ER stress induction following acute liver-specific deletion of HMG-CoA reductase	14
Platelets induce free and phospholipid-esterified 12-hydroxyeicosatetraenoic acid generation in colon cancer cells by delivering 12-lipoxygenase	14
Characterization of long-chain fatty acid-linked bile acids: a major conjugation form of 3β-hydroxy bile acids in feces	14
Baat Gene Knockout Alters Post-Natal Development, the Gut Microbiome, and Reveals Unusual Bile Acids in Mice	14
ANGPTL4 silencing via antisense oligonucleotides reduces plasma triglycerides and glucose in mice without causing lymphadenopathy	14
Simvastatin inhibits POVPC-mediated induction of endothelial-to-mesenchymal cell transition	13
Human cholesteryl ester transfer protein lacks lipopolysaccharide transfer activity, but worsens inflammation and sepsis outcomes in mice	13
Ileal bile acid transporter inhibition in Cyp2c70 KO mice ameliorates cholestatic liver injury	13
Adiponectin forms a complex with atherogenic LDL and inhibits its downstream effects	13
1-Deoxysphingolipid synthesis compromises anchorage-independent growth and plasma membrane endocytosis in cancer cells	12
Development and validation of an isoform-independent monoclonal antibody–based ELISA for measurement of lipoprotein(a)	12
Low production of 12α-hydroxylated bile acids prevents hepatic steatosis in Cyp2c70−/− mice by reducing fat absorption	12
Gene networks and pathways for plasma lipid traits via multitissue multiomics systems analysis	12
Mass spectrometry imaging of phosphatidylcholine metabolism in lungs administered with therapeutic surfactants and isotopic tracers	12
A closer look at the mysterious HSD17B13	12
The effects of cardiolipin on the structural dynamics of the mitochondrial ADP/ATP carrier in its cytosol-open state	12
Artifactual FA dimers mimic FAHFA signals in untargeted metabolomics pipelines	12
Deletion of lysophosphatidylcholine acyltransferase 3 in myeloid cells worsens hepatic steatosis after a high-fat diet	12
4β-Hydroxycholesterol is a prolipogenic factor that promotes SREBP1c expression and activity through the liver X receptor	12
Apolipoprotein A-I modulates HDL particle size in the absence of apolipoprotein A-II	12
Identification and characterization of 3-ketosphinganine reductase activity encoded at the BT_0972 locus in Bacteroides thetaiotaomicron	12
Hormone-sensitive lipase is localized at synapses and is necessary for normal memory functioning in mice	12
Simultaneous analyses of urinary eicosanoids and related mediators identified tetranor-prostaglandin E metabolite as a novel biomarker of diabetic nephropathy	12
Isomeric lipid signatures reveal compartmentalized fatty acid metabolism in cancer	12
A sensitive S-Trap-based approach to the analysis of T cell lipid raft proteome	12
Sterol regulatory element-binding protein Sre1 regulates carotenogenesis in the red yeast Xanthophyllomyces dendrorhous	12
Apolipoprotein E content of VLDL limits LPL-mediated triglyceride hydrolysis	11
Elevated de novo lipogenesis, slow liver triglyceride turnover, and clinical correlations in nonalcoholic steatohepatitis patients	11
10,12-Conjugated linoleic acid supplementation improves HDL composition and function in mice	11
Chronic cholesterol depletion increases F-actin levels and induces cytoskeletal reorganization via a dual mechanism	11
1-Deoxysphinganine initiates adaptive responses to serine and glycine starvation in cancer cells via proteolysis of sphingosine kinase	11
Serum dihydroceramides correlate with insulin sensitivity in humans and decrease insulin sensitivity in vitro	11
Insights into the kinetics and dynamics of the furin-cleaved form of PCSK9	11
Loss of plasma membrane lipid asymmetry can induce ordered domain (raft) formation	11
Antisense oligonucleotide–mediated inhibition of angiopoietin-like protein 3 increases reverse cholesterol transport in mice	11
Relationship of apolipoprotein(a) isoform size with clearance and production of lipoprotein(a) in a diverse cohort	11
ELOVL4 Mutations That Cause Spinocerebellar Ataxia-34 Differentially Alter Very Long Chain Fatty Acid Biosynthesis	11
Signaling roles of phosphoinositides in the retina	11
Cholesterol sulfate fluidizes the sterol fraction of the stratum corneum lipid phase and increases its permeability	11
MBOAT7-driven lysophosphatidylinositol acylation in adipocytes contributes to systemic glucose homeostasis	10
Consequences of excessive glucosylsphingosine in glucocerebrosidase-deficient zebrafish.	10
Spatial profiling of gangliosides in mouse brain by mass spectrometry imaging	10
A systematic review of the natural history and biomarkers of primary lecithin:cholesterol acyltransferase deficiency	10
Genetic dissection in mice reveals a dynamic crosstalk between the delivery pathways of vitamin A	10
Identification of unusual phospholipids from bovine heart mitochondria by HPLC-MS/MS	10
Quantification of common and planar bile acids in tissues and cultured cells	10
Red blood cell triglycerides—a unique pool that incorporates plasma-free fatty acids and relates to metabolic health	10
Assessing the role of glycosphingolipids in the phenotype severity of Fabry disease mouse model	10
Effect of sphingosine and phytosphingosine ceramide ratio on lipid arrangement and barrier function in skin lipid models	10
Imaging cholesterol depletion at the plasma membrane by methyl-β-cyclodextrin	10
Lipid droplet membrane proteome remodeling parallels ethanol-induced hepatic steatosis and its resolution	10

CXCL5 secreted from macrophages during cold exposure mediates white adipose tissue browning	10
Obesity reprograms the pulmonary polyunsaturated fatty acid-derived lipidome, transcriptome, and gene-oxylipin networks	10
PANDORA-Seq unveils the hidden small noncoding RNA landscape in atherosclerosis of LDL receptor-deficient mice	10
ω-O-Acylceramides but not ω-hydroxy ceramides are required for healthy lamellar phase architecture of skin barrier lipids	10
Myeloid deletion and therapeutic activation of AMPK do not alter atherosclerosis in male or female mice	10
Vitamin D deficiency promotes accumulation of bioactive lipids and increased endocannabinoid tone in zebrafish	10
Cannabinoid type 1 receptor inverse agonism attenuates dyslipidemia and atherosclerosis in APOE∗3-Leiden.CETP mice	10
Novel contact sites between lipid droplets, early endosomes, and the endoplasmic reticulum	9
Transgelin: a new gene involved in LDL endocytosis identified by a genome-wide CRISPR-Cas9 screen	9
Integrated LC-MS metabolomics with dual derivatization for quantification of FFAs in fecal samples of hepatocellular carcinoma patients	9
High Sensitivity and Wide Linearity LC-MS/MS Method for Oxylipin Quantification in Multiple Biological Samples	9
ASTER-B regulates mitochondrial carotenoid transport and homeostasis	9
Cholesterol synthesis enzyme SC4MOL is fine-tuned by sterols and targeted for degradation by the E3 ligase MARCHF6	9
Phosphatidic Acid Mediates the Nem1-Spo7/Pah1 Phosphatase Cascade in Yeast Lipid Synthesis	9
Oxidized phospholipids cause changes in jejunum mucus that induce dysbiosis and systemic inflammation	9
A simple, rapid, and sensitive fluorescence-based method to assess triacylglycerol hydrolase activity	9
Identification and characterization of LPLAT7 as an sn-1-specific lysophospholipid acyltransferase	9
Genetic Mimicry Analysis Reveals the Specific Lipases Targeted by the ANGPTL3-ANGPTL8 Complex and ANGPTL4	9
Liver-specific FGFR4 knockdown in mice on an HFD increases bile acid synthesis and improves hepatic steatosis	9
rHDL modeling and the anchoring mechanism of LCAT activation	9
Distinct patterns of apolipoprotein C-I, C-II, and C-III isoforms are associated with markers of Alzheimer’s disease	9
ANGPTL4 sensitizes lipoprotein lipase to PCSK3 cleavage by catalyzing its unfolding	9