Journal of Lipid Research

Papers
(The TQCC of Journal of Lipid Research is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)
ArticleCitations
Plasma S1P and Sphingosine are not Different Prior to Pre-Eclampsia in Women at High Risk of Developing the Disease157
Bioorthogonal azido-S1P works as substrate for S1PR1106
Specific approaches and limitations in (multi)-omic Mendelian randomization67
A simplified method for preventing postmortem alterations of brain prostanoids for true in situ level quantification55
Four-dimensional lipidomics profiling in X-linked adrenoleukodystrophy using trapped ion mobility mass spectrometry54
A comprehensive measure of Golgi sphingolipid flux using NBD C6-ceramide: evaluation of sphingolipid inhibitors51
Nuclear lipid droplets in Caco2 cells originate from nascent precursors and in situ at the nuclear envelope47
Measuring Lp(a) particles with a novel isoform-insensitive immunoassay illustrates efficacy of muvalaplin46
Cardiomyopathy in a c.1528G>C Hadha mouse is associated with cardiac tissue lipotoxicity and altered cardiolipin species42
Elevation of hepatic de novo lipogenesis in mice with overnutrition is dependent on multiple substrates40
Altered hepatic lipid droplet morphology and lipid metabolism in fasted Plin2-null mice39
Functional characterization of 16 variants found in the low-density lipoprotein receptor (LDLR) gene39
TMEM241 is a UDP-N-acetylglucosamine transporter required for M6P modification of NPC2 and cholesterol transport35
Development of a novel spatiotemporal depletion system for cellular cholesterol33
The role of lysosomal phospholipase A2 in the catabolism of bis(monoacylglycerol)phosphate and association with phospholipidosis30
Generation of hepatoma cell lines deficient in microsomal triglyceride transfer protein28
Dietary docosahexaenoic acid (DHA) downregulates liver DHA synthesis by inhibiting eicosapentaenoic acid elongation25
In memoriam: Ana Jonas, PhD24
Effects of exercise training on ANGPTL3/8 and ANGPTL4/8 and their associations with cardiometabolic traits24
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Creation of a novel zebrafish model with low DHA status to study the role of maternal nutrition during neurodevelopment23
ABHD4 regulates adipocyte differentiation in vitro but does not affect adipose tissue lipid metabolism in mice23
The role of high-density lipoproteins in sepsis23
Hepatocytes Deficient in Nuclear Envelope Protein Lamina-associated Polypeptide 1 are an Ideal Mammalian System to Study Intranuclear Lipid Droplets23
KIAA1363 affects retinyl ester turnover in cultured murine and human hepatic stellate cells22
Lipidomics and mass spectrometry imaging unveil alterations in mice hippocampus lipid composition exposed to hypoxia21
Choline kinase inhibition promotes ER-phagy21
A fluorogenic substrate for the detection of lipid amidases in intact cells21
Dietary modulation of Lp(a): more questions than answers21
Brown adipose tissue facilitates the fever response following infection with Salmonella enterica serovar Typhimurium in mice20
Development and application of an LC-MS/MS method for the combined quantification of oxysterols and bile acids19
The adipocyte apolipoprotein M is negatively associated with inflammation19
The one-key-to-two-doors role of lipidomics: plasma lipidome, cardiovascular risk and statin usage19
Eicosapentaenoic Acid Ameliorates Cardiac Fibrosis and Tissue Inflammation in Spontaneously Hypertensive Rats19
Widespread but moderate genetic overlap between circulating polyunsaturated fatty acids and brain disorders19
Effect of IL-6R blockade on plasma lipids and clinical outcomes among hospitalized patients with COVID-19 infection19
Deep-lipidotyping by mass spectrometry: recent technical advances and applications18
Corrigendum to Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway18
Introduction of a lipidomics scoring system for data quality assessment18
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The role of N-terminal phosphorylation of DGK-θ17
TLR4 in POMC neurons regulates thermogenesis in a sex-dependent manner17
Diet-induced obesity dampens the temporal oscillation of hepatic mitochondrial lipids17
Efficacy of a novel PCSK9 inhibitory peptide alone and with evinacumab in a mouse model of atherosclerosis17
Detergent-induced quantitatively limited formation of diacyl phosphatidylinositol dimannoside in Mycobacterium smegmatis16
DFCP1 is a regulator of starvation-driven ATGL-mediated lipid droplet lipolysis16
2-Hydroxypropyl-β-cyclodextrin mitigates pathological changes in a mouse model of retinal cholesterol dyshomeostasis16
Dissecting cell type–specific impact in lysosomal acid lipase deficiency–associated disorders16
Metabolic switch from glycogen to lipid in the liver maintains glucose homeostasis in neonatal mice16
Saroglitazar is noninferior to fenofibrate in reducing triglyceride levels in hypertriglyceridemic patients in a randomized clinical trial16
Characterizing genetic profiles for high triglyceride levels in U.S. patients of African ancestry16
In Memoriam: Jan B Sjövall, MD, PhD, (1928–2024)15
Elevated high-density lipoprotein triglycerides increase atherosclerotic risk15
A facile assay for zDHHC palmitoyl transferase activation elucidates effects of mutation and modification15
Polyunsaturated fatty acids stimulate immunity and eicosanoid production in Drosophila melanogaster15
Hepatic Deletion of X-Box Binding Protein 1 in FXR Null Mice Leads to Enhanced Liver Injury15
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Fatty acid nitroalkenes regulate intestinal lipid absorption15
Highly tail-asymmetric lipids interdigitate and cause bidirectional ordering15
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Repurposing daclatasvir for MASLD Therapy—A promising step forward with challenges ahead14
Spatial lipidomics of coronary atherosclerotic plaque development in a familial hypercholesterolemia swine model14
Phosphatidic Acid Mediates the Nem1-Spo7/Pah1 Phosphatase Cascade in Yeast Lipid Synthesis14
Lipidomic analysis of Porphyromonas gingivalis reveals novel glycerol bisphosphoceramide, phosphatidyl-, and phosphoglycerol dipeptide lipid families14
Glucosylceramide flippases contribute to cellular glucosylceramide homeostasis14
EBF2 regulates cardiolipin and phosphatidylethanolamine remodeling and mitochondrial dynamics in brown fat14
Phosphatidylserine-decorated delivery platform helps alleviate acute lung injury via potentiating macrophage targeting14
Elevated n-3/n-6 PUFA ratio in early life diet reverses adverse intrauterine kidney programming in female rats14
Associations between serum cholesterol and immunophenotypical characteristics of circulatory B cells and Tregs14
Circadian PER1 controls daily fat absorption with the regulation of PER1-PKA on phosphorylation of bile acid synthetase14
Apolipoprotein A1 and high-density lipoprotein limit low-density lipoprotein transcytosis by binding SR-B114
Heptanol-mediated phase separation determines phase preference of molecules in live cell membranes14
Mice deficient in ER protein seipin have reduced adrenal cholesteryl ester lipid droplet formation and utilization14
Association of plasma ceramide with decline in kidney function in patients with type 2 diabetes13
Dysregulation of mitochondrial dynamics and mitophagy are involved in high-fat diet-induced steroidogenesis inhibition13
Consequences of excessive glucosylsphingosine in glucocerebrosidase-deficient zebrafish.13
Tripartite motif 38 alleviates the pathological process of NAFLD–NASH by promoting TAB2 degradation13
Intravital lipid droplet labeling and imaging reveals the phenotypes and functions of individual macrophages in vivo13
ORMDL mislocalization by impaired autophagy in Niemann-Pick type C disease leads to increased de novo sphingolipid biosynthesis13
HBV-miR-3 induces hepatic cholesterol accumulation by targeting ABCA1: Evidence for potential benefits of statin usage13
GCKIII kinases control hepatocellular lipid homeostasis via shared mode of action13
High-density lipoproteins mediate small RNA intercellular communication between dendritic cells and macrophages13
Metallothionein 1B attenuates inflammation and hepatic steatosis in MASH by inhibiting the AKT/PI3K pathway13
Cardiolipin remodeling maintains the inner mitochondrial membrane in cells with saturated lipidomes13
Decreased sarcoplasmic reticulum phospholipids in human skeletal muscle are associated with metabolic syndrome13
Quantitative characterizations of the cholesterol-related pathways in the retina and brain of hamsters12
Reducing saturated fat intake lowers LDL-C but increases Lp(a) levels in African Americans: the GET-READI feeding trial12
Untargeted lipidomics reveals novel HDL metabotypes and lipid-clinical correlates12
Triglyceride-rich lipoprotein, remnant cholesterol, and apolipoproteins CII, CIII, and E in patients with schizophrenia12
Liver proteomics identifies a disconnect between proteins associated with de novo lipogenesis and triglyceride storage12
Alternative fatty acid desaturation pathways revealed by deep profiling of total fatty acids in RAW 264.7 cell line12
Disruption of nucleotide biosynthesis reprograms mitochondrial metabolism to inhibit adipogenesis12
Microbial products linked to steatohepatitis are reduced by deletion of nuclear hormone receptor SHP in mice12
Comprehensive mass spectrometry lipidomics of human biofluids and ocular tissues12
Individual and simultaneous treatment with antipsychotic aripiprazole and antidepressant trazodone inhibit sterol biosynthesis in the adult brain12
Combining ASBT inhibitor and FGF15 treatments enhances therapeutic efficacy against cholangiopathy in female but not male Cyp2c70 KO mice12
Differential expression patterns of phospholipase D isoforms 1 and 2 in the mammalian brain and retina11
Magnetic resonance imaging detects white adipose tissue beiging in mice following PDE10A inhibitor treatment11
Detecting white adipose tissue browning in mice with in vivo R2∗ mapping at 9.4T MRI11
Causal association of blood lipids with all-cause and cause-specific mortality risk: a Mendelian randomization study11
Substrate-dependent incorporation of 15-lipoxygenase products in glycerophospholipids: 15-HETE and 15-HEPE in PI, 17-HDHA in plasmalogen PE, and 13-HODE in PC11
Participation of lipids in the tumor response to photodynamic therapy and its exploitation for therapeutic gain11
Distinct pathways for the absorption and metabolism of β-carotene and zeaxanthin in the mouse intestine11
Unraveling the genetic background of individuals with a clinical familial hypercholesterolemia phenotype11
NEGR1 deficiency disrupts lipid metabolism and steroidogenesis in Leydig cells, linking testosterone to behavior11
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De(C1P)hering the role of ceramide-1-phosphate levels in skin wound healing11
Strategies for consistent and automated quantification of HDL proteome using data-independent acquisition11
APOA5 deficiency causes hypertriglyceridemia by reducing amounts of lipoprotein lipase in capillaries11
Lipid and Lipoprotein Metabolism in Microglia: Alzheimer’s Disease Mechanisms and Interventions11
Measurement of 7-dehydrocholesterol and cholesterol in hair can be used in the diagnosis of Smith-Lemli-Opitz syndrome11
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Comparison between genetic and pharmaceutical disruption of Ldlr expression for the development of atherosclerosis11
Hormone-sensitive lipase protects adipose triglyceride lipase-deficient mice from lethal lipotoxic cardiomyopathy11
Potential causal evidence for an ApoB-independent and HDL-related risk profile associated with coronary artery disease10
Hsp90α promotes lipogenesis by stabilizing FASN and promoting FASN transcription via LXRα in hepatocellular carcinoma10
Characteristic distribution of eicosapentaenoic acid in human abdominal aortic aneurysm wall10
Brown fat fuels the fire in fever10
Peridroplet mitochondria are associated with the severity of MASLD and the prevention of MASLD by diethyldithiocarbamate10
A multi-ancestry genome-wide association study and evaluation of polygenic scores of LDL-C levels10
Sorting through the extensive and confusing roles of sortilin in metabolic disease10
Blocking Lipid Uptake Pathways Does not Prevent Toxicity in Adipose Triglyceride Lipase (ATGL) Deficiency10
Effects of apolipoprotein H downregulation on lipid metabolism, fatty liver disease, and gut microbiota dysbiosis10
Global deletion of COX-2 attenuates hepatic inflammation but impairs metabolic homeostasis in diet-induced obesity10
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Competitive displacement of lipoprotein lipase from heparan sulfate is orchestrated by a disordered acidic cluster in GPIHBP110
Maternal DHA intake in mice increased DHA metabolites in the pup brain and ameliorated MeHg-induced behavioral disorder10
Ceramide kinase regulates acute wound healing by suppressing 5-oxo-ETE biosynthesis and signaling via its receptor OXER110
6-O-alkyl 4-methylumbelliferyl-β-D-glucosides as selective substrates for GBA1 in the discovery of glycosylated sterols10
Sphingomyelin is involved in regulating UCP1-mediated nonshivering thermogenesis9
SDCCAG3 inhibits adipocyte hypertrophy and improves obesity-related metabolic disorders via SDCCAG3/SMURF1/PPARγ axis9
Unbiased insights into the multiplicity of the CYP46A1 brain effects in 5XFAD mice treated with low dose-efavirenz9
The Non Catalytic Protein ERG28 has a Functional Role in Cholesterol Synthesis and is Coregulated Transcriptionally9
The lipidomics reporting checklist a framework for transparency of lipidomic experiments and repurposing resource data9
Vascular lipid droplets formed in response to TNF, hypoxia, or OA: biochemical composition and prostacyclin generation9
In Memoriam: G. Stephen (Steve) Tint, PhD (1935–2022)9
A targeted proteomics method for quantifying plasma apolipoprotein kinetics in individual mice using stable isotope labeling9
Decoding the role of angiopoietin-like protein 4/8 complex–mediated plasmin generation in the regulation of LPL activity9
Associations between insulin-like growth factor binding protein-2 and lipoprotein kinetics in men9
Adipose Tissue, Bile Acids, and Gut Microbiome Species Associated With Gallstones After Bariatric Surgery9
Insulin dysregulation drives mitochondrial cholesterol metabolite accumulation: initiating hepatic toxicity in nonalcoholic fatty liver disease9
Loss of Splicing Factor SRSF3 Impairs Lipophagy Through Ubiquitination and Degradation of Syntaxin17 in Hepatocytes9
Sphingosine kinase 1 is involved in triglyceride breakdown by maintaining lysosomal integrity in brown adipocytes9
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Pharmacological SERCA activation limits diet-induced steatohepatitis and restores liver metabolic function in mice9
A historical, evidence-based, and narrative review on commonly used dietary supplements in lipid-lowering9
The DNA methyltransferase inhibitor decitabine blunts the response to a high-animal fat and protein diet in mice9
The SGLT2 inhibitor dapagliflozin promotes systemic FFA mobilization, enhances hepatic β-oxidation, and induces ketosis9
Targeting to high density lipoprotein cholesterol: new insights for inflammatory bowel disease treatment9
Pioglitazone alleviates lacrimal gland impairments induced by high-fat diet by suppressing M1 polarization9
Mining cholesterol genes from thousands of mouse livers identifies aldolase C as a regulator of cholesterol biosynthesis9
A high-cholesterol zebrafish diet promotes hypercholesterolemia and fasting-associated liver steatosis9
Flavonoids regulate LDLR through different mechanisms tied to their specific structures9
A high-resolution 13C NMR approach for profiling fatty acid unsaturation in lipid extracts and in live Caenorhabditis elegans8
Potential causal and temporal relationship between plasma triglyceride levels and circulating leukocyte8
Changes in soluble LDL receptor and lipoprotein fractions in response to diet in the DIETFITS weight loss study8
Does small HDL’s function improve when lipid-lowering alters its composition?8
Apolipoprotein F concentration, activity, and the properties of LDL controlling ApoF activation in hyperlipidemic plasma8
Unmasking crucial residues in adipose triglyceride lipase for coactivation with comparative gene identification-588
Determination of tissue contributions to the circulating lipid pool in cold exposure via systematic assessment of lipid profiles8
Circulating membrane aminophospholipids contribute to thrombotic risk in rheumatoid arthritis8
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2-fluoro-1-methylpyridinium p-toluene sulfonate: a new LC-MS/MS derivatization reagent for vitamin D metabolites8
Hexokinase 2 promotes ISGylation of Acyl-CoA synthetase long-chain family member 4 in sepsis-induced microglia cells8
Maternal obesogenic diet enhances cholestatic liver disease in offspring8
The antidepressant drug sertraline is a novel inhibitor of yeast Pah1 and human lipin 1 phosphatidic acid phosphatases8
1-Deoxysphinganine initiates adaptive responses to serine and glycine starvation in cancer cells via proteolysis of sphingosine kinase8
Specific FAHFAs predict worsening glucose tolerance in non-diabetic relatives of people with Type 2 diabetes8
All-trans retinoic acid induces lipophagy by reducing Rubicon in Hepa1c1c7 cells8
Acute retinol mobilization by retinol-binding protein 4 in mouse liver induces fibroblast growth factor 21 expression8
Lipidomics of phospholipase A2 reveals exquisite specificity in macrophages8
Relationship of apolipoprotein(a) isoform size with clearance and production of lipoprotein(a) in a diverse cohort8
A basic model for the association of ligands with membrane cholesterol: application to cytolysin binding8
A novel mutation, Ile344Asn, in microsomal triglyceride transfer protein abolishes binding to protein disulfide isomerase8
Human apoA-I[Lys107del] mutation affects lipid surface behavior of apoA-I and its ability to form large nascent HDL8
LC-MS based simultaneous profiling of adrenal hormones of steroids, catecholamines, and metanephrines8
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The Risk of Going Outside: Amino Phospholipids in Rheumatoid Arthritis8
Spatial lipidomics reveals zone-specific hepatic lipid alteration and remodeling in metabolic dysfunction-associated steatohepatitis8
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