Journal of Lipid Research

Article	Citations
Plasma S1P and Sphingosine are not Different Prior to Pre-Eclampsia in Women at High Risk of Developing the Disease	157
Bioorthogonal azido-S1P works as substrate for S1PR1	106
Specific approaches and limitations in (multi)-omic Mendelian randomization	67
A simplified method for preventing postmortem alterations of brain prostanoids for true in situ level quantification	55
Four-dimensional lipidomics profiling in X-linked adrenoleukodystrophy using trapped ion mobility mass spectrometry	54
A comprehensive measure of Golgi sphingolipid flux using NBD C6-ceramide: evaluation of sphingolipid inhibitors	51
Nuclear lipid droplets in Caco2 cells originate from nascent precursors and in situ at the nuclear envelope	47
Measuring Lp(a) particles with a novel isoform-insensitive immunoassay illustrates efficacy of muvalaplin	46
Cardiomyopathy in a c.1528G>C Hadha mouse is associated with cardiac tissue lipotoxicity and altered cardiolipin species	42
Elevation of hepatic de novo lipogenesis in mice with overnutrition is dependent on multiple substrates	40
Functional characterization of 16 variants found in the low-density lipoprotein receptor (LDLR) gene	39
Altered hepatic lipid droplet morphology and lipid metabolism in fasted Plin2-null mice	39
TMEM241 is a UDP-N-acetylglucosamine transporter required for M6P modification of NPC2 and cholesterol transport	35
Development of a novel spatiotemporal depletion system for cellular cholesterol	33
The role of lysosomal phospholipase A2 in the catabolism of bis(monoacylglycerol)phosphate and association with phospholipidosis	30
Generation of hepatoma cell lines deficient in microsomal triglyceride transfer protein	28
Dietary docosahexaenoic acid (DHA) downregulates liver DHA synthesis by inhibiting eicosapentaenoic acid elongation	25
Cover	24
In memoriam: Ana Jonas, PhD	24
Effects of exercise training on ANGPTL3/8 and ANGPTL4/8 and their associations with cardiometabolic traits	24
Cover	24
ABHD4 regulates adipocyte differentiation in vitro but does not affect adipose tissue lipid metabolism in mice	23
The role of high-density lipoproteins in sepsis	23
Hepatocytes Deficient in Nuclear Envelope Protein Lamina-associated Polypeptide 1 are an Ideal Mammalian System to Study Intranuclear Lipid Droplets	23
Creation of a novel zebrafish model with low DHA status to study the role of maternal nutrition during neurodevelopment	23

KIAA1363 affects retinyl ester turnover in cultured murine and human hepatic stellate cells	22
Choline kinase inhibition promotes ER-phagy	21
A fluorogenic substrate for the detection of lipid amidases in intact cells	21
Dietary modulation of Lp(a): more questions than answers	21
Lipidomics and mass spectrometry imaging unveil alterations in mice hippocampus lipid composition exposed to hypoxia	21
Brown adipose tissue facilitates the fever response following infection with Salmonella enterica serovar Typhimurium in mice	20
The one-key-to-two-doors role of lipidomics: plasma lipidome, cardiovascular risk and statin usage	19
Eicosapentaenoic Acid Ameliorates Cardiac Fibrosis and Tissue Inflammation in Spontaneously Hypertensive Rats	19
Widespread but moderate genetic overlap between circulating polyunsaturated fatty acids and brain disorders	19
Effect of IL-6R blockade on plasma lipids and clinical outcomes among hospitalized patients with COVID-19 infection	19
Development and application of an LC-MS/MS method for the combined quantification of oxysterols and bile acids	19
The adipocyte apolipoprotein M is negatively associated with inflammation	19
Introduction of a lipidomics scoring system for data quality assessment	18
Cover	18
Deep-lipidotyping by mass spectrometry: recent technical advances and applications	18
Corrigendum to Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway	18
TLR4 in POMC neurons regulates thermogenesis in a sex-dependent manner	17
Diet-induced obesity dampens the temporal oscillation of hepatic mitochondrial lipids	17
Efficacy of a novel PCSK9 inhibitory peptide alone and with evinacumab in a mouse model of atherosclerosis	17
The role of N-terminal phosphorylation of DGK-θ	17
Saroglitazar is noninferior to fenofibrate in reducing triglyceride levels in hypertriglyceridemic patients in a randomized clinical trial	16
Characterizing genetic profiles for high triglyceride levels in U.S. patients of African ancestry	16
Detergent-induced quantitatively limited formation of diacyl phosphatidylinositol dimannoside in Mycobacterium smegmatis	16
DFCP1 is a regulator of starvation-driven ATGL-mediated lipid droplet lipolysis	16
2-Hydroxypropyl-β-cyclodextrin mitigates pathological changes in a mouse model of retinal cholesterol dyshomeostasis	16
Dissecting cell type–specific impact in lysosomal acid lipase deficiency–associated disorders	16
Metabolic switch from glycogen to lipid in the liver maintains glucose homeostasis in neonatal mice	16
Polyunsaturated fatty acids stimulate immunity and eicosanoid production in Drosophila melanogaster	15
Hepatic Deletion of X-Box Binding Protein 1 in FXR Null Mice Leads to Enhanced Liver Injury	15
Cover	15
Fatty acid nitroalkenes regulate intestinal lipid absorption	15
Highly tail-asymmetric lipids interdigitate and cause bidirectional ordering	15
In Memoriam: Jan B Sjövall, MD, PhD, (1928–2024)	15
Elevated high-density lipoprotein triglycerides increase atherosclerotic risk	15
A facile assay for zDHHC palmitoyl transferase activation elucidates effects of mutation and modification	15
Glucosylceramide flippases contribute to cellular glucosylceramide homeostasis	14
EBF2 regulates cardiolipin and phosphatidylethanolamine remodeling and mitochondrial dynamics in brown fat	14
Phosphatidylserine-decorated delivery platform helps alleviate acute lung injury via potentiating macrophage targeting	14
Elevated n-3/n-6 PUFA ratio in early life diet reverses adverse intrauterine kidney programming in female rats	14
Associations between serum cholesterol and immunophenotypical characteristics of circulatory B cells and Tregs	14
Circadian PER1 controls daily fat absorption with the regulation of PER1-PKA on phosphorylation of bile acid synthetase	14
Apolipoprotein A1 and high-density lipoprotein limit low-density lipoprotein transcytosis by binding SR-B1	14
Heptanol-mediated phase separation determines phase preference of molecules in live cell membranes	14
Mice deficient in ER protein seipin have reduced adrenal cholesteryl ester lipid droplet formation and utilization	14
Cover	14
Repurposing daclatasvir for MASLD Therapy—A promising step forward with challenges ahead	14
Spatial lipidomics of coronary atherosclerotic plaque development in a familial hypercholesterolemia swine model	14
Phosphatidic Acid Mediates the Nem1-Spo7/Pah1 Phosphatase Cascade in Yeast Lipid Synthesis	14
Lipidomic analysis of Porphyromonas gingivalis reveals novel glycerol bisphosphoceramide, phosphatidyl-, and phosphoglycerol dipeptide lipid families	14
GCKIII kinases control hepatocellular lipid homeostasis via shared mode of action	13

High-density lipoproteins mediate small RNA intercellular communication between dendritic cells and macrophages	13
Metallothionein 1B attenuates inflammation and hepatic steatosis in MASH by inhibiting the AKT/PI3K pathway	13
Cardiolipin remodeling maintains the inner mitochondrial membrane in cells with saturated lipidomes	13
Decreased sarcoplasmic reticulum phospholipids in human skeletal muscle are associated with metabolic syndrome	13
Association of plasma ceramide with decline in kidney function in patients with type 2 diabetes	13
Dysregulation of mitochondrial dynamics and mitophagy are involved in high-fat diet-induced steroidogenesis inhibition	13
Consequences of excessive glucosylsphingosine in glucocerebrosidase-deficient zebrafish.	13
Tripartite motif 38 alleviates the pathological process of NAFLD–NASH by promoting TAB2 degradation	13
Intravital lipid droplet labeling and imaging reveals the phenotypes and functions of individual macrophages in vivo	13
ORMDL mislocalization by impaired autophagy in Niemann-Pick type C disease leads to increased de novo sphingolipid biosynthesis	13
HBV-miR-3 induces hepatic cholesterol accumulation by targeting ABCA1: Evidence for potential benefits of statin usage	13
Quantitative characterizations of the cholesterol-related pathways in the retina and brain of hamsters	12
Reducing saturated fat intake lowers LDL-C but increases Lp(a) levels in African Americans: the GET-READI feeding trial	12
Untargeted lipidomics reveals novel HDL metabotypes and lipid-clinical correlates	12
Liver proteomics identifies a disconnect between proteins associated with de novo lipogenesis and triglyceride storage	12
Alternative fatty acid desaturation pathways revealed by deep profiling of total fatty acids in RAW 264.7 cell line	12
Disruption of nucleotide biosynthesis reprograms mitochondrial metabolism to inhibit adipogenesis	12
Combining ASBT inhibitor and FGF15 treatments enhances therapeutic efficacy against cholangiopathy in female but not male Cyp2c70 KO mice	12
Microbial products linked to steatohepatitis are reduced by deletion of nuclear hormone receptor SHP in mice	12
Comprehensive mass spectrometry lipidomics of human biofluids and ocular tissues	12
Individual and simultaneous treatment with antipsychotic aripiprazole and antidepressant trazodone inhibit sterol biosynthesis in the adult brain	12
Triglyceride-rich lipoprotein, remnant cholesterol, and apolipoproteins CII, CIII, and E in patients with schizophrenia	12
Comparison between genetic and pharmaceutical disruption of Ldlr expression for the development of atherosclerosis	11
Hormone-sensitive lipase protects adipose triglyceride lipase-deficient mice from lethal lipotoxic cardiomyopathy	11
Differential expression patterns of phospholipase D isoforms 1 and 2 in the mammalian brain and retina	11
Magnetic resonance imaging detects white adipose tissue beiging in mice following PDE10A inhibitor treatment	11
Detecting white adipose tissue browning in mice with in vivo R2∗ mapping at 9.4T MRI	11
Causal association of blood lipids with all-cause and cause-specific mortality risk: a Mendelian randomization study	11
Substrate-dependent incorporation of 15-lipoxygenase products in glycerophospholipids: 15-HETE and 15-HEPE in PI, 17-HDHA in plasmalogen PE, and 13-HODE in PC	11
Participation of lipids in the tumor response to photodynamic therapy and its exploitation for therapeutic gain	11
Distinct pathways for the absorption and metabolism of β-carotene and zeaxanthin in the mouse intestine	11
Unraveling the genetic background of individuals with a clinical familial hypercholesterolemia phenotype	11
NEGR1 deficiency disrupts lipid metabolism and steroidogenesis in Leydig cells, linking testosterone to behavior	11
Cover	11
De(C1P)hering the role of ceramide-1-phosphate levels in skin wound healing	11
Strategies for consistent and automated quantification of HDL proteome using data-independent acquisition	11
APOA5 deficiency causes hypertriglyceridemia by reducing amounts of lipoprotein lipase in capillaries	11
Lipid and Lipoprotein Metabolism in Microglia: Alzheimer’s Disease Mechanisms and Interventions	11
Measurement of 7-dehydrocholesterol and cholesterol in hair can be used in the diagnosis of Smith-Lemli-Opitz syndrome	11
Cover	11
Potential causal evidence for an ApoB-independent and HDL-related risk profile associated with coronary artery disease	10
Hsp90α promotes lipogenesis by stabilizing FASN and promoting FASN transcription via LXRα in hepatocellular carcinoma	10
Characteristic distribution of eicosapentaenoic acid in human abdominal aortic aneurysm wall	10
Brown fat fuels the fire in fever	10
Peridroplet mitochondria are associated with the severity of MASLD and the prevention of MASLD by diethyldithiocarbamate	10
A multi-ancestry genome-wide association study and evaluation of polygenic scores of LDL-C levels	10
Sorting through the extensive and confusing roles of sortilin in metabolic disease	10
Blocking Lipid Uptake Pathways Does not Prevent Toxicity in Adipose Triglyceride Lipase (ATGL) Deficiency	10
Effects of apolipoprotein H downregulation on lipid metabolism, fatty liver disease, and gut microbiota dysbiosis	10
Global deletion of COX-2 attenuates hepatic inflammation but impairs metabolic homeostasis in diet-induced obesity	10
Cover	10
Competitive displacement of lipoprotein lipase from heparan sulfate is orchestrated by a disordered acidic cluster in GPIHBP1	10
Maternal DHA intake in mice increased DHA metabolites in the pup brain and ameliorated MeHg-induced behavioral disorder	10
Ceramide kinase regulates acute wound healing by suppressing 5-oxo-ETE biosynthesis and signaling via its receptor OXER1	10
6-O-alkyl 4-methylumbelliferyl-β-D-glucosides as selective substrates for GBA1 in the discovery of glycosylated sterols	10
A high-cholesterol zebrafish diet promotes hypercholesterolemia and fasting-associated liver steatosis	9
Flavonoids regulate LDLR through different mechanisms tied to their specific structures	9
Sphingomyelin is involved in regulating UCP1-mediated nonshivering thermogenesis	9
SDCCAG3 inhibits adipocyte hypertrophy and improves obesity-related metabolic disorders via SDCCAG3/SMURF1/PPARγ axis	9
Unbiased insights into the multiplicity of the CYP46A1 brain effects in 5XFAD mice treated with low dose-efavirenz	9
The Non Catalytic Protein ERG28 has a Functional Role in Cholesterol Synthesis and is Coregulated Transcriptionally	9
The lipidomics reporting checklist a framework for transparency of lipidomic experiments and repurposing resource data	9
Vascular lipid droplets formed in response to TNF, hypoxia, or OA: biochemical composition and prostacyclin generation	9
In Memoriam: G. Stephen (Steve) Tint, PhD (1935–2022)	9
A targeted proteomics method for quantifying plasma apolipoprotein kinetics in individual mice using stable isotope labeling	9
Decoding the role of angiopoietin-like protein 4/8 complex–mediated plasmin generation in the regulation of LPL activity	9
Associations between insulin-like growth factor binding protein-2 and lipoprotein kinetics in men	9
Adipose Tissue, Bile Acids, and Gut Microbiome Species Associated With Gallstones After Bariatric Surgery	9
Insulin dysregulation drives mitochondrial cholesterol metabolite accumulation: initiating hepatic toxicity in nonalcoholic fatty liver disease	9
Loss of Splicing Factor SRSF3 Impairs Lipophagy Through Ubiquitination and Degradation of Syntaxin17 in Hepatocytes	9
Sphingosine kinase 1 is involved in triglyceride breakdown by maintaining lysosomal integrity in brown adipocytes	9
Cover	9
Pharmacological SERCA activation limits diet-induced steatohepatitis and restores liver metabolic function in mice	9
A historical, evidence-based, and narrative review on commonly used dietary supplements in lipid-lowering	9
The DNA methyltransferase inhibitor decitabine blunts the response to a high-animal fat and protein diet in mice	9
The SGLT2 inhibitor dapagliflozin promotes systemic FFA mobilization, enhances hepatic β-oxidation, and induces ketosis	9
Targeting to high density lipoprotein cholesterol: new insights for inflammatory bowel disease treatment	9
Pioglitazone alleviates lacrimal gland impairments induced by high-fat diet by suppressing M1 polarization	9
Mining cholesterol genes from thousands of mouse livers identifies aldolase C as a regulator of cholesterol biosynthesis	9
Cover	8

The Risk of Going Outside: Amino Phospholipids in Rheumatoid Arthritis	8
A high-resolution 13C NMR approach for profiling fatty acid unsaturation in lipid extracts and in live Caenorhabditis elegans	8
Lipidomics of phospholipase A2 reveals exquisite specificity in macrophages	8
Potential causal and temporal relationship between plasma triglyceride levels and circulating leukocyte	8
Changes in soluble LDL receptor and lipoprotein fractions in response to diet in the DIETFITS weight loss study	8
Does small HDL’s function improve when lipid-lowering alters its composition?	8
Apolipoprotein F concentration, activity, and the properties of LDL controlling ApoF activation in hyperlipidemic plasma	8
Unmasking crucial residues in adipose triglyceride lipase for coactivation with comparative gene identification-58	8
Determination of tissue contributions to the circulating lipid pool in cold exposure via systematic assessment of lipid profiles	8
Cover	8
Hexokinase 2 promotes ISGylation of Acyl-CoA synthetase long-chain family member 4 in sepsis-induced microglia cells	8
Spatial lipidomics reveals zone-specific hepatic lipid alteration and remodeling in metabolic dysfunction-associated steatohepatitis	8
Maternal obesogenic diet enhances cholestatic liver disease in offspring	8
The antidepressant drug sertraline is a novel inhibitor of yeast Pah1 and human lipin 1 phosphatidic acid phosphatases	8
1-Deoxysphinganine initiates adaptive responses to serine and glycine starvation in cancer cells via proteolysis of sphingosine kinase	8
Specific FAHFAs predict worsening glucose tolerance in non-diabetic relatives of people with Type 2 diabetes	8
All-trans retinoic acid induces lipophagy by reducing Rubicon in Hepa1c1c7 cells	8
Acute retinol mobilization by retinol-binding protein 4 in mouse liver induces fibroblast growth factor 21 expression	8
Relationship of apolipoprotein(a) isoform size with clearance and production of lipoprotein(a) in a diverse cohort	8
Circulating membrane aminophospholipids contribute to thrombotic risk in rheumatoid arthritis	8
A basic model for the association of ligands with membrane cholesterol: application to cytolysin binding	8
2-fluoro-1-methylpyridinium p-toluene sulfonate: a new LC-MS/MS derivatization reagent for vitamin D metabolites	8
A novel mutation, Ile344Asn, in microsomal triglyceride transfer protein abolishes binding to protein disulfide isomerase	8
Human apoA-I[Lys107del] mutation affects lipid surface behavior of apoA-I and its ability to form large nascent HDL	8
LC-MS based simultaneous profiling of adrenal hormones of steroids, catecholamines, and metanephrines	8