Journal of Lipid Research

Article	Citations
Cardiomyopathy in a c.1528G>C Hadha mouse is associated with cardiac tissue lipotoxicity and altered cardiolipin species	170
Functional characterization of 16 variants found in the LDL receptor gene	133
Development of a novel spatiotemporal depletion system for cellular cholesterol	71
Expression of SREBF2 and HMGCR discriminates the viability of steatotic grafts for human liver transplantation	60
The role of lysosomal phospholipase A2 in the catabolism of bis(monoacylglycerol)phosphate and association with phospholipidosis	54
Erratum to: The antidepressant drug sertraline is a novel inhibitor of yeast Pah1 and human lipin 1 phosphatidic acid phosphatases [Journal of Lipid Research 66/1 (2025) 100711]	53
Measuring Lp(a) particles with a novel isoform-insensitive immunoassay illustrates efficacy of muvalaplin	51
Nuclear lipid droplets in Caco2 cells originate from nascent precursors and in situ at the nuclear envelope	51
Bioorthogonal azido-S1P works as substrate for S1PR1	46
Dietary docosahexaenoic acid (DHA) downregulates liver DHA synthesis by inhibiting eicosapentaenoic acid elongation	43
A comprehensive measure of Golgi sphingolipid flux using NBD C6-ceramide: evaluation of sphingolipid inhibitors	43
A simplified method for preventing postmortem alterations of brain prostanoids for true in situ level quantification	40
Four-dimensional lipidomics profiling in X-linked adrenoleukodystrophy using trapped ion mobility mass spectrometry	38
Plasma S1P and Sphingosine are not Different Prior to Pre-Eclampsia in Women at High Risk of Developing the Disease	35
Elevation of hepatic de novo lipogenesis in mice with overnutrition is dependent on multiple substrates	32
Altered hepatic lipid droplet morphology and lipid metabolism in fasted Plin2-null mice	29
Specific approaches and limitations in (multi)-omic Mendelian randomization	29
Generation of hepatoma cell lines deficient in microsomal triglyceride transfer protein	27
In memoriam: Ana Jonas, PhD	26
TMEM241 is a UDP-N-acetylglucosamine transporter required for M6P modification of NPC2 and cholesterol transport	26
Cover	25
Brown adipose tissue facilitates the fever response following infection with Salmonella enterica serovar Typhimurium in mice	25
Development and application of an LC-MS/MS method for the combined quantification of oxysterols and bile acids	25
Dietary modulation of Lp(a): more questions than answers	25
Choline kinase inhibition promotes ER-phagy	24

A fluorogenic substrate for the detection of lipid amidases in intact cells	24
Hepatocytes Deficient in Nuclear Envelope Protein Lamina-associated Polypeptide 1 are an Ideal Mammalian System to Study Intranuclear Lipid Droplets	23
Cover	23
Eicosapentaenoic Acid Ameliorates Cardiac Fibrosis and Tissue Inflammation in Spontaneously Hypertensive Rats	22
The one-key-to-two-doors role of lipidomics: plasma lipidome, cardiovascular risk and statin usage	22
Introduction of a lipidomics scoring system for data quality assessment	21
The adipocyte apolipoprotein M is negatively associated with inflammation	20
Creation of a novel zebrafish model with low DHA status to study the role of maternal nutrition during neurodevelopment	20
Effects of exercise training on ANGPTL3/8 and ANGPTL4/8 and their associations with cardiometabolic traits	20
Lipidomics and mass spectrometry imaging unveil alterations in mice hippocampus lipid composition exposed to hypoxia	19
Widespread but moderate genetic overlap between circulating polyunsaturated fatty acids and brain disorders	19
METTL3-mediated m6A modification of TNFAIP3 promotes endothelial to mesenchymal transition and atherosclerosis via the NF-κB/Snail signaling pathway	19
Effect of IL-6R blockade on plasma lipids and clinical outcomes among hospitalized patients with COVID-19 infection	19
Fatty acid nitroalkenes regulate intestinal lipid absorption	18
KIAA1363 affects retinyl ester turnover in cultured murine and human hepatic stellate cells	18
In Memoriam: Jan B Sjövall, MD, PhD, (1928–2024)	18
Efficacy of a novel PCSK9 inhibitory peptide alone and with evinacumab in a mouse model of atherosclerosis	18
ABHD4 regulates adipocyte differentiation in vitro but does not affect adipose tissue lipid metabolism in mice	18
DFCP1 is a regulator of starvation-driven ATGL-mediated lipid droplet lipolysis	18
Deep-lipidotyping by mass spectrometry: recent technical advances and applications	18
The role of high-density lipoproteins in sepsis	18
Elevated high-density lipoprotein triglycerides increase atherosclerotic risk	17
Cover	17
TLR4 in POMC neurons regulates thermogenesis in a sex-dependent manner	17
Corrigendum to Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway	17
The role of N-terminal phosphorylation of DGK-θ	17
Highly tail-asymmetric lipids interdigitate and cause bidirectional ordering	17
Dissecting cell type–specific impact in lysosomal acid lipase deficiency–associated disorders	17
Metabolic switch from glycogen to lipid in the liver maintains glucose homeostasis in neonatal mice	17
Asprosin as a regulator of hepatic lipogenesis and its association with hepatic steatosis	16
Apolipoprotein A5 reduces clearance of VLDL by altering apolipoprotein E content	16
Hepatic Deletion of X-Box Binding Protein 1 in FXR Null Mice Leads to Enhanced Liver Injury	16
Diet-induced obesity dampens the temporal oscillation of hepatic mitochondrial lipids	16
Resolving versus non-resolving sphingolipid dynamics during macrophage activation: a time-resolved metabolic analysis	16
2-Hydroxypropyl-β-cyclodextrin mitigates pathological changes in a mouse model of retinal cholesterol dyshomeostasis	16
Characterizing genetic profiles for high triglyceride levels in U.S. patients of African ancestry	16
Detergent-induced quantitatively limited formation of diacyl phosphatidylinositol dimannoside in Mycobacterium smegmatis	16
Mitochondrial cardiolipin remodeling facilitates efficient myoblast differentiation	16
Polyunsaturated fatty acids stimulate immunity and eicosanoid production in Drosophila melanogaster	16
Saroglitazar is noninferior to fenofibrate in reducing triglyceride levels in hypertriglyceridemic patients in a randomized clinical trial	15
Circadian PER1 controls daily fat absorption with the regulation of PER1-PKA on phosphorylation of bile acid synthetase	15
Heptanol-mediated phase separation determines phase preference of molecules in live cell membranes	15
Spatial lipidomics of coronary atherosclerotic plaque development in a familial hypercholesterolemia swine model	15
Cover	15
Phosphatidic Acid Mediates the Nem1-Spo7/Pah1 Phosphatase Cascade in Yeast Lipid Synthesis	15
Phosphatidylserine-decorated delivery platform helps alleviate acute lung injury via potentiating macrophage targeting	15
Lipidomic analysis of Porphyromonas gingivalis reveals novel glycerol bisphosphoceramide, phosphatidyl-, and phosphoglycerol dipeptide lipid families	15
Associations between serum cholesterol and immunophenotypical characteristics of circulatory B cells and Tregs	15
A facile assay for zDHHC palmitoyl transferase activation elucidates effects of mutation and modification	15
Elevated n-3/n-6 PUFA ratio in early life diet reverses adverse intrauterine kidney programming in female rats	15

Glucosylceramide flippases contribute to cellular glucosylceramide homeostasis	15
Repurposing daclatasvir for MASLD Therapy—A promising step forward with challenges ahead	15
EBF2 regulates cardiolipin and phosphatidylethanolamine remodeling and mitochondrial dynamics in brown fat	14
Tripartite motif 38 alleviates the pathological process of NAFLD–NASH by promoting TAB2 degradation	14
Mice deficient in ER protein seipin have reduced adrenal cholesteryl ester lipid droplet formation and utilization	14
Cover	14
Cover	14
Apolipoprotein A1 and high-density lipoprotein limit low-density lipoprotein transcytosis by binding SR-B1	14
Association of plasma ceramide with decline in kidney function in patients with type 2 diabetes	14
High-density lipoproteins mediate small RNA intercellular communication between dendritic cells and macrophages	13
Intravital lipid droplet labeling and imaging reveals the phenotypes and functions of individual macrophages in vivo	13
Decreased sarcoplasmic reticulum phospholipids in human skeletal muscle are associated with metabolic syndrome	13
Metallothionein 1B attenuates inflammation and hepatic steatosis in MASH by inhibiting the AKT/PI3K pathway	13
Dysregulation of mitochondrial dynamics and mitophagy are involved in high-fat diet-induced steroidogenesis inhibition	13
GCKIII kinases control hepatocellular lipid homeostasis via shared mode of action	13
ORMDL mislocalization by impaired autophagy in Niemann-Pick type C disease leads to increased de novo sphingolipid biosynthesis	13
Participation of lipids in the tumor response to photodynamic therapy and its exploitation for therapeutic gain	13
Consequences of excessive glucosylsphingosine in glucocerebrosidase-deficient zebrafish.	13
HBV-miR-3 induces hepatic cholesterol accumulation by targeting ABCA1: Evidence for potential benefits of statin usage	13
Cardiolipin remodeling maintains the inner mitochondrial membrane in cells with saturated lipidomes	13
Individual and simultaneous treatment with antipsychotic aripiprazole and antidepressant trazodone inhibit sterol biosynthesis in the adult brain	12
Measurement of 7-dehydrocholesterol and cholesterol in hair can be used in the diagnosis of Smith-Lemli-Opitz syndrome	12
Combining ASBT inhibitor and FGF15 treatments enhances therapeutic efficacy against cholangiopathy in female but not male Cyp2c70 KO mice	12
Comprehensive mass spectrometry lipidomics of human biofluids and ocular tissues	12
NEGR1 deficiency disrupts lipid metabolism and steroidogenesis in Leydig cells, linking testosterone to behavior	12
Detecting white adipose tissue browning in mice with in vivo R2∗ mapping at 9.4T MRI	12
Microbial products linked to steatohepatitis are reduced by deletion of nuclear hormone receptor SHP in mice	12
Triglyceride-rich lipoprotein, remnant cholesterol, and apolipoproteins CII, CIII, and E in patients with schizophrenia	12
Causal association of blood lipids with all-cause and cause-specific mortality risk: a Mendelian randomization study	12
Alternative fatty acid desaturation pathways revealed by deep profiling of total fatty acids in RAW 264.7 cell line	12
Disruption of nucleotide biosynthesis reprograms mitochondrial metabolism to inhibit adipogenesis	12
Quantitative characterizations of the cholesterol-related pathways in the retina and brain of hamsters	12
Reducing saturated fat intake lowers LDL-C but increases Lp(a) levels in African Americans: the GET-READI feeding trial	12
Untargeted lipidomics reveals novel HDL metabotypes and lipid-clinical correlates	12
Liver proteomics identifies a disconnect between proteins associated with de novo lipogenesis and triglyceride storage	12
Unraveling the genetic background of individuals with a clinical familial hypercholesterolemia phenotype	11
Characteristic distribution of eicosapentaenoic acid in human abdominal aortic aneurysm wall	11
Cover	11
Comparison between genetic and pharmaceutical disruption of Ldlr expression for the development of atherosclerosis	11
Hormone-sensitive lipase protects adipose triglyceride lipase-deficient mice from lethal lipotoxic cardiomyopathy	11
Substrate-dependent incorporation of 15-lipoxygenase products in glycerophospholipids: 15-HETE and 15-HEPE in PI, 17-HDHA in plasmalogen PE, and 13-HODE in PC	11
Lipid and lipoprotein metabolism in microglia: Alzheimer’s disease mechanisms and interventions	11
Differential expression patterns of phospholipase D isoforms 1 and 2 in the mammalian brain and retina	11
APOA5 deficiency causes hypertriglyceridemia by reducing amounts of lipoprotein lipase in capillaries	11
Cover	11
Cover	11
Distinct pathways for the absorption and metabolism of β-carotene and zeaxanthin in the mouse intestine	11
Magnetic resonance imaging detects white adipose tissue beiging in mice following PDE10A inhibitor treatment	11
Endothelial SR-B1 is dispensable for thermogenesis but promotes selective cholesterol uptake in brown adipose tissue	11
Competitive displacement of lipoprotein lipase from heparan sulfate is orchestrated by a disordered acidic cluster in GPIHBP1	11
Hsp90α promotes lipogenesis by stabilizing FASN and promoting FASN transcription via LXRα in hepatocellular carcinoma	11
Strategies for consistent and automated quantification of HDL proteome using data-independent acquisition	11
De(C1P)hering the role of ceramide-1-phosphate levels in skin wound healing	11
A multi-ancestry genome-wide association study and evaluation of polygenic scores of LDL-C levels	11
Sorting through the extensive and confusing roles of sortilin in metabolic disease	11
Global deletion of COX-2 attenuates hepatic inflammation but impairs metabolic homeostasis in diet-induced obesity	10
The Non Catalytic Protein ERG28 has a Functional Role in Cholesterol Synthesis and is Coregulated Transcriptionally	10
Sphingomyelin is involved in regulating UCP1-mediated nonshivering thermogenesis	10
Vascular lipid droplets formed in response to TNF, hypoxia, or OA: biochemical composition and prostacyclin generation	10
Decoding the role of angiopoietin-like protein 4/8 complex–mediated plasmin generation in the regulation of LPL activity	10
The lipidomics reporting checklist a framework for transparency of lipidomic experiments and repurposing resource data	10
Potential causal evidence for an ApoB-independent and HDL-related risk profile associated with coronary artery disease	10
Insulin dysregulation drives mitochondrial cholesterol metabolite accumulation: initiating hepatic toxicity in nonalcoholic fatty liver disease	10
Adipose Tissue, Bile Acids, and Gut Microbiome Species Associated With Gallstones After Bariatric Surgery	10
6-O-alkyl 4-methylumbelliferyl-β-D-glucosides as selective substrates for GBA1 in the discovery of glycosylated sterols	10
Mitochondria-specific photorelease of ceramide induces apoptosis	10
Pharmacological SERCA activation limits diet-induced steatohepatitis and restores liver metabolic function in mice	10
The SGLT2 inhibitor dapagliflozin promotes systemic FFA mobilization, enhances hepatic β-oxidation, and induces ketosis	10
The DNA methyltransferase inhibitor decitabine blunts the response to a high-animal fat and protein diet in mice	10
Blocking Lipid Uptake Pathways Does not Prevent Toxicity in Adipose Triglyceride Lipase (ATGL) Deficiency	10
Peridroplet mitochondria are associated with the severity of MASLD and the prevention of MASLD by diethyldithiocarbamate	10
Maternal DHA intake in mice increased DHA metabolites in the pup brain and ameliorated MeHg-induced behavioral disorder	10
Targeting to high density lipoprotein cholesterol: new insights for inflammatory bowel disease treatment	10
Unbiased insights into the multiplicity of the CYP46A1 brain effects in 5XFAD mice treated with low dose-efavirenz	10
Associations between insulin-like growth factor binding protein-2 and lipoprotein kinetics in men	10
Ceramide kinase regulates acute wound healing by suppressing 5-oxo-ETE biosynthesis and signaling via its receptor OXER1	10
Effects of apolipoprotein H downregulation on lipid metabolism, fatty liver disease, and gut microbiota dysbiosis	10
Brown fat fuels the fire in fever	10
Cover	9
A high-cholesterol zebrafish diet promotes hypercholesterolemia and fasting-associated liver steatosis	9

Mining cholesterol genes from thousands of mouse livers identifies aldolase C as a regulator of cholesterol biosynthesis	9
Acute retinol mobilization by retinol-binding protein 4 in mouse liver induces fibroblast growth factor 21 expression	9
Lipidomics of phospholipase A2 reveals exquisite specificity in macrophages	9
Sphingosine kinase 1 is involved in triglyceride breakdown by maintaining lysosomal integrity in brown adipocytes	9
A historical, evidence-based, and narrative review on commonly used dietary supplements in lipid-lowering	9
SDCCAG3 inhibits adipocyte hypertrophy and improves obesity-related metabolic disorders via SDCCAG3/SMURF1/PPARγ axis	9
Loss of Splicing Factor SRSF3 Impairs Lipophagy Through Ubiquitination and Degradation of Syntaxin17 in Hepatocytes	9
Cover	9
A novel mutation, Ile344Asn, in microsomal triglyceride transfer protein abolishes binding to protein disulfide isomerase	9
A targeted proteomics method for quantifying plasma apolipoprotein kinetics in individual mice using stable isotope labeling	9
Flavonoids regulate LDLR through different mechanisms tied to their specific structures	9
Pioglitazone alleviates lacrimal gland impairments induced by high-fat diet by suppressing M1 polarization	9
All-trans retinoic acid induces lipophagy by reducing Rubicon in Hepa1c1c7 cells	9
Unmasking crucial residues in adipose triglyceride lipase for coactivation with comparative gene identification-58	9
Circulating membrane aminophospholipids contribute to thrombotic risk in rheumatoid arthritis	9
Determination of tissue contributions to the circulating lipid pool in cold exposure via systematic assessment of lipid profiles	8
Potential causal and temporal relationship between plasma triglyceride levels and circulating leukocyte	8
In Memoriam: G. Stephen (Steve) Tint, PhD (1935–2022)	8
LC-MS based simultaneous profiling of adrenal hormones of steroids, catecholamines, and metanephrines	8
WITHDRAWN: The Risk of Going Outside: Amino Phospholipids in Rheumatoid Arthritis	8
Apolipoprotein F concentration, activity, and the properties of LDL controlling ApoF activation in hyperlipidemic plasma	8
1-Deoxysphinganine initiates adaptive responses to serine and glycine starvation in cancer cells via proteolysis of sphingosine kinase	8
Cover	8
Relationship of apolipoprotein(a) isoform size with clearance and production of lipoprotein(a) in a diverse cohort	8
Hexokinase 2 promotes ISGylation of Acyl-CoA synthetase long-chain family member 4 in sepsis-induced microglia cells	8
Spatial lipidomics reveals zone-specific hepatic lipid alteration and remodeling in metabolic dysfunction-associated steatohepatitis	8
Specific FAHFAs predict worsening glucose tolerance in non-diabetic relatives of people with Type 2 diabetes	8
2-fluoro-1-methylpyridinium p-toluene sulfonate: a new LC-MS/MS derivatization reagent for vitamin D metabolites	8
Dietary phospholipid carriers of DHA do not increase brain DHA levels: A replication study	8