Journal of Lipid Research

Papers
(The median citation count of Journal of Lipid Research is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
A simplified method for preventing postmortem alterations of brain prostanoids for true in situ level quantification133
Nuclear lipid droplets in Caco2 cells originate from nascent precursors and in situ at the nuclear envelope70
Generation of hepatoma cell lines deficient in microsomal triglyceride transfer protein55
Plasma S1P and Sphingosine are not Different Prior to Pre-Eclampsia in Women at High Risk of Developing the Disease46
Bioorthogonal azido-S1P works as substrate for S1PR145
Measuring Lp(a) particles with a novel isoform-insensitive immunoassay illustrates efficacy of muvalaplin43
Specific approaches and limitations in (multi)-omic Mendelian randomization41
TMEM241 is a UDP-N-acetylglucosamine transporter required for M6P modification of NPC2 and cholesterol transport38
Development of a novel spatiotemporal depletion system for cellular cholesterol35
Four-dimensional lipidomics profiling in X-linked adrenoleukodystrophy using trapped ion mobility mass spectrometry34
Altered hepatic lipid droplet morphology and lipid metabolism in fasted Plin2-null mice32
A comprehensive measure of Golgi sphingolipid flux using NBD C6-ceramide: evaluation of sphingolipid inhibitors31
Cardiomyopathy in a c.1528G>C Hadha mouse is associated with cardiac tissue lipotoxicity and altered cardiolipin species29
The role of lysosomal phospholipase A2 in the catabolism of bis(monoacylglycerol)phosphate and association with phospholipidosis27
Dietary docosahexaenoic acid (DHA) downregulates liver DHA synthesis by inhibiting eicosapentaenoic acid elongation25
In memoriam: Ana Jonas, PhD24
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ABHD4 regulates adipocyte differentiation in vitro but does not affect adipose tissue lipid metabolism in mice22
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Eicosapentaenoic Acid Ameliorates Cardiac Fibrosis and Tissue Inflammation in Spontaneously Hypertensive Rats20
Hepatocytes Deficient in Nuclear Envelope Protein Lamina-associated Polypeptide 1 are an Ideal Mammalian System to Study Intranuclear Lipid Droplets20
Effect of IL-6R blockade on plasma lipids and clinical outcomes among hospitalized patients with COVID-19 infection19
Effects of exercise training on ANGPTL3/8 and ANGPTL4/8 and their associations with cardiometabolic traits19
The role of high-density lipoproteins in sepsis19
Lipidomics and mass spectrometry imaging unveil alterations in mice hippocampus lipid composition exposed to hypoxia19
Development and application of an LC-MS/MS method for the combined quantification of oxysterols and bile acids19
A fluorogenic substrate for the detection of lipid amidases in intact cells18
Choline kinase inhibition promotes ER-phagy18
The adipocyte apolipoprotein M is negatively associated with inflammation17
Creation of a novel zebrafish model with low DHA status to study the role of maternal nutrition during neurodevelopment16
Dietary modulation of Lp(a): more questions than answers16
Brown adipose tissue facilitates the fever response following infection with Salmonella enterica serovar Typhimurium in mice16
KIAA1363 affects retinyl ester turnover in cultured murine and human hepatic stellate cells16
Deep-lipidotyping by mass spectrometry: recent technical advances and applications15
Polyunsaturated fatty acids stimulate immunity and eicosanoid production in Drosophila melanogaster15
The one-key-to-two-doors role of lipidomics: Plasma lipidome, cardiovascular risk and statin usage15
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Corrigendum to Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway14
Saroglitazar is noninferior to fenofibrate in reducing triglyceride levels in hypertriglyceridemic patients in a randomized clinical trial14
The role of N-terminal phosphorylation of DGK-θ14
Hepatic Deletion of X-Box Binding Protein 1 in FXR Null Mice Leads to Enhanced Liver Injury14
Diet-induced obesity dampens the temporal oscillation of hepatic mitochondrial lipids13
Metabolic switch from glycogen to lipid in the liver maintains glucose homeostasis in neonatal mice13
Characterizing genetic profiles for high triglyceride levels in U.S. patients of African ancestry13
Mice deficient in ER protein seipin have reduced adrenal cholesteryl ester lipid droplet formation and utilization13
Highly tail-asymmetric lipids interdigitate and cause bidirectional ordering13
DFCP1 is a regulator of starvation-driven ATGL-mediated lipid droplet lipolysis13
Elevated high-density lipoprotein triglycerides increase atherosclerotic risk13
Detergent-induced quantitatively limited formation of diacyl phosphatidylinositol dimannoside in Mycobacterium smegmatis13
Efficacy of a novel PCSK9 inhibitory peptide alone and with evinacumab in a mouse model of atherosclerosis13
TLR4 in POMC neurons regulates thermogenesis in a sex-dependent manner13
Dissecting cell type–specific impact in lysosomal acid lipase deficiency–associated disorders13
2-Hydroxypropyl-β-cyclodextrin mitigates pathological changes in a mouse model of retinal cholesterol dyshomeostasis13
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A facile assay for zDHHC palmitoyl transferase activation elucidates effects of mutation and modification12
Lipidomic analysis of Porphyromonas gingivalis reveals novel glycerol bisphosphoceramide, phosphatidyl-, and phosphoglycerol dipeptide lipid families12
Spatial lipidomics of coronary atherosclerotic plaque development in a familial hypercholesterolemia swine model12
Consequences of excessive glucosylsphingosine in glucocerebrosidase-deficient zebrafish.12
Heptanol-mediated phase separation determines phase preference of molecules in live cell membranes12
Glucosylceramide flippases contribute to cellular glucosylceramide homeostasis12
Phosphatidylserine decorated delivery platform helps alleviate acute lung injury via potentiating macrophage targeting12
ORMDL mislocalization by impaired autophagy in Niemann-Pick type C disease leads to increased de novo sphingolipid biosynthesis12
Elevated n-3/n-6 PUFA ratio in early life diet reverses adverse intrauterine kidney programming in female rats12
Circadian PER1 controls daily fat absorption with the regulation of PER1-PKA on phosphorylation of bile acid synthetase12
Phosphatidic Acid Mediates the Nem1-Spo7/Pah1 Phosphatase Cascade in Yeast Lipid Synthesis12
Associations between serum cholesterol and immunophenotypical characteristics of circulatory B cells and Tregs12
Apolipoprotein A1 and high-density lipoprotein limit low-density lipoprotein transcytosis by binding SR-B112
Dysregulation of mitochondrial dynamics and mitophagy are involved in high-fat diet-induced steroidogenesis inhibition12
Detecting white adipose tissue browning in mice with in vivo R2∗ mapping at 9.4T MRI11
Combining ASBT inhibitor and FGF15 treatments enhances therapeutic efficacy against cholangiopathy in female but not male Cyp2c70 KO mice11
Intravital lipid droplet labeling and imaging reveals the phenotypes and functions of individual macrophages in vivo11
Association of plasma ceramide with decline in kidney function in patients with type 2 diabetes11
Metallothionein 1B attenuates inflammation and hepatic steatosis in MASH by inhibiting the AKT/PI3K pathway11
Liver proteomics identifies a disconnect between proteins associated with de novo lipogenesis and triglyceride storage11
Tripartite motif 38 alleviates the pathological process of NAFLD–NASH by promoting TAB2 degradation11
Decreased sarcoplasmic reticulum phospholipids in human skeletal muscle are associated with metabolic syndrome11
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Participation of lipids in the tumor response to photodynamic therapy and its exploitation for therapeutic gain11
Microbial products linked to steatohepatitis are reduced by deletion of nuclear hormone receptor SHP in mice11
GCKIII kinases control hepatocellular lipid homeostasis via shared mode of action11
Cardiolipin remodeling maintains the inner mitochondrial membrane in cells with saturated lipidomes11
High-density lipoproteins mediate small RNA intercellular communication between dendritic cells and macrophages11
Untargeted lipidomics reveals novel HDL metabotypes and lipid-clinical correlates10
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Reducing saturated fat intake lowers LDL-C but increases Lp(a) levels in African Americans: the GET-READI feeding trial10
Individual and simultaneous treatment with antipsychotic aripiprazole and antidepressant trazodone inhibit sterol biosynthesis in the adult brain10
Hsp90α promotes lipogenesis by stabilizing FASN and promoting FASN transcription via LXRα in hepatocellular carcinoma10
Measurement of 7-dehydrocholesterol and cholesterol in hair can be used in the diagnosis of Smith-Lemli-Opitz syndrome10
Magnetic resonance imaging detects white adipose tissue beiging in mice following PDE10A inhibitor treatment10
Alternative fatty acid desaturation pathways revealed by deep profiling of total fatty acids in RAW 264.7 cell line10
Disruption of nucleotide biosynthesis reprograms mitochondrial metabolism to inhibit adipogenesis10
Triglyceride-rich lipoprotein, remnant cholesterol, and apolipoproteins CII, CIII, and E in patients with schizophrenia10
Strategies for consistent and automated quantification of HDL proteome using data-independent acquisition10
Causal association of blood lipids with all-cause and cause-specific mortality risk: a Mendelian randomization study10
Differential expression patterns of phospholipase D isoforms 1 and 2 in the mammalian brain and retina10
De(C1P)hering the role of ceramide-1-phosphate levels in skin wound healing10
Quantitative characterizations of the cholesterol-related pathways in the retina and brain of hamsters10
Comprehensive mass spectrometry lipidomics of human biofluids and ocular tissues10
APOA5 deficiency causes hypertriglyceridemia by reducing amounts of lipoprotein lipase in capillaries10
A multi-ancestry genome-wide association study and evaluation of polygenic scores of LDL-C levels9
Unraveling the genetic background of individuals with a clinical familial hypercholesterolemia phenotype9
Competitive displacement of lipoprotein lipase from heparan sulfate is orchestrated by a disordered acidic cluster in GPIHBP19
6-O-alkyl 4-methylumbelliferyl-β-D-glucosides as selective substrates for GBA1 in the discovery of glycosylated sterols9
The Non Catalytic Protein ERG28 has a Functional Role in Cholesterol Synthesis and is Coregulated Transcriptionally9
Comparison between genetic and pharmaceutical disruption of Ldlr expression for the development of atherosclerosis9
Sorting through the extensive and confusing roles of sortilin in metabolic disease9
Adipose Tissue, Bile Acids, and Gut Microbiome Species Associated With Gallstones After Bariatric Surgery9
Brown fat fuels the fire in fever9
Blocking Lipid Uptake Pathways Does not Prevent Toxicity in Adipose Triglyceride Lipase (ATGL) Deficiency9
Hormone-sensitive lipase protects adipose triglyceride lipase-deficient mice from lethal lipotoxic cardiomyopathy9
Distinct pathways for the absorption and metabolism of β-carotene and zeaxanthin in the mouse intestine9
Characteristic distribution of eicosapentaenoic acid in human abdominal aortic aneurysm wall9
Unbiased insights into the multiplicity of the CYP46A1 brain effects in 5XFAD mice treated with low dose-efavirenz9
Mining cholesterol genes from thousands of mouse livers identifies aldolase C as a regulator of cholesterol biosynthesis8
The lipidomics reporting checklist a framework for transparency of lipidomic experiments and repurposing resource data8
Insulin dysregulation drives mitochondrial cholesterol metabolite accumulation: initiating hepatic toxicity in nonalcoholic fatty liver disease8
Pioglitazone alleviates lacrimal gland impairments induced by high-fat diet by suppressing M1 polarization8
A high-cholesterol zebrafish diet promotes hypercholesterolemia and fasting-associated liver steatosis8
Sphingomyelin is involved in regulating UCP1-mediated nonshivering thermogenesis8
Decoding the role of angiopoietin-like protein 4/8 complex–mediated plasmin generation in the regulation of LPL activity8
A historical, evidence-based, and narrative review on commonly used dietary supplements in lipid-lowering8
Ceramide kinase regulates acute wound healing by suppressing 5-oxo-ETE biosynthesis and signaling via its receptor OXER18
Potential causal evidence for an ApoB-independent and HDL-related risk profile associated with coronary artery disease8
Maternal DHA intake in mice increased DHA metabolites in the pup brain and ameliorated MeHg-induced behavioral disorder8
Vascular lipid droplets formed in response to TNF, hypoxia, or OA: biochemical composition and prostacyclin generation8
Flavonoids regulate LDLR through different mechanisms tied to their specific structures8
The DNA methyltransferase inhibitor decitabine blunts the response to a high-animal fat and protein diet in mice8
SDCCAG3 inhibits adipocyte hypertrophy and improves obesity-related metabolic disorders via SDCCAG3/SMURF1/PPARγ axis8
The SGLT2 inhibitor dapagliflozin promotes systemic FFA mobilization, enhances hepatic β-oxidation, and induces ketosis8
Effects of apolipoprotein H downregulation on lipid metabolism, fatty liver disease, and gut microbiota dysbiosis8
Peridroplet mitochondria are associated with the severity of MASLD and the prevention of MASLD by diethyldithiocarbamate8
Associations between insulin-like growth factor binding protein-2 and lipoprotein kinetics in men8
Loss of Splicing Factor SRSF3 Impairs Lipophagy Through Ubiquitination and Degradation of Syntaxin17 in Hepatocytes8
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Pharmacological SERCA activation limits diet-induced steatohepatitis and restores liver metabolic function in mice7
All-trans retinoic acid induces lipophagy by reducing Rubicon in Hepa1c1c7 cells7
Unmasking crucial residues in adipose triglyceride lipase for coactivation with comparative gene identification-587
Acute retinol mobilization by retinol-binding protein 4 in mouse liver induces fibroblast growth factor 21 expression7
In Memoriam: G. Stephen (Steve) Tint, PhD (1935–2022)7
A targeted proteomics method for quantifying plasma apolipoprotein kinetics in individual mice using stable isotope labeling7
Lipidomics of phospholipase A2 reveals exquisite specificity in macrophages7
Determination of tissue contributions to the circulating lipid pool in cold exposure via systematic assessment of lipid profiles7
LC-MS based simultaneous profiling of adrenal hormones of steroids, catecholamines, and metanephrines7
A novel mutation, Ile344Asn, in microsomal triglyceride transfer protein abolishes binding to protein disulfide isomerase7
2-fluoro-1-methylpyridinium p-toluene sulfonate: a new LC-MS/MS derivatization reagent for vitamin D metabolites7
Sphingosine kinase 1 is involved in triglyceride breakdown by maintaining lysosomal integrity in brown adipocytes7
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Relationship of apolipoprotein(a) isoform size with clearance and production of lipoprotein(a) in a diverse cohort7
Apolipoprotein F concentration, activity, and the properties of LDL controlling ApoF activation in hyperlipidemic plasma7
Potential causal and temporal relationship between plasma triglyceride levels and circulating leukocyte6
A basic model for the association of ligands with membrane cholesterol: application to cytolysin binding6
Does small HDL’s function improve when lipid-lowering alters its composition?6
Inositol acylation of phosphatidylinositol mannosides: a rapid mass response to membrane fluidization in mycobacteria6
Hexokinase 2 promotes ISGylation of Acyl-CoA synthetase long-chain family member 4 in sepsis-induced microglia cells6
Toxoplasma acyl-CoA synthetase TgACS3 is crucial to channel host fatty acids in lipid droplets and for parasite propagation6
Insights into the molecular changes of adipocyte dedifferentiation and its future research opportunities6
Correction: Unmasking crucial residues in adipose triglyceride lipase for coactivation with comparative gene identification-586
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Elovl4b knockout zebrafish as a model for ocular very-long-chain PUFA deficiency6
Human apoA-I[Lys107del] mutation affects lipid surface behavior of apoA-I and its ability to form large nascent HDL6
Maternal obesogenic diet enhances cholestatic liver disease in offspring6
A high-resolution 13C NMR approach for profiling fatty acid unsaturation in lipid extracts and in live Caenorhabditis elegans6
Unveiling the role of Mfsd2a and LPC-DHA in kidney repair6
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Spatial lipidomics reveals zone-specific hepatic lipid alteration and remodeling in metabolic dysfunction-associated steatohepatitis6
Changes in soluble LDL receptor and lipoprotein fractions in response to diet in the DIETFITS weight loss study6
The antidepressant drug sertraline is a novel inhibitor of yeast Pah1 and human lipin 1 phosphatidic acid phosphatases6
The sphingosine kinase 2 inhibitors ABC294640 and K145 elevate (dihydro)sphingosine 1-phosphate levels in various cells6
ANGPTL4/8 promotes plasmin-mediated cleavage of LPL inhibitors6
Effect of type 2 diabetes on the inducible degrader of LDL receptor6
1-Deoxysphinganine initiates adaptive responses to serine and glycine starvation in cancer cells via proteolysis of sphingosine kinase6
A fatty acid-ordered plasma membrane environment is critical for Ebola virus matrix protein assembly and budding5
Whole picture of human stratum corneum ceramides, including the chain-length diversity of long-chain bases5
Visualize neuronal membrane cholesterol with split-fluorescent protein tagged YDQA sensor5
Ichthyosis linked to sphingosine 1-phosphate lyase insufficiency is due to aberrant sphingolipid and calcium regulation5
Cholesteryl hemiazelate identified in CVD patients causes in vitro and in vivo inflammation5
Chronic cholesterol depletion increases F-actin levels and induces cytoskeletal reorganization via a dual mechanism5
Bioactive lipid mediators in plasma are predictors of preeclampsia irrespective of aspirin therapy5
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Cholesterol affects the binding of proteins to phosphatidic acid without influencing its ionization properties5
ASTER-B regulates mitochondrial carotenoid transport and homeostasis5
Sulfatide with ceramide composed of phytosphingosine (t18:0) and 2-hydroxy FAs in renal intercalated cells5
Genetic deletion or pharmacologic inhibition of the Nlrp3 inflammasome did not ameliorate experimental NASH5
Effects of coconut oil, olive oil, and butter on plasma fatty acids and metabolic risk factors: a randomized trial5
High Sensitivity and Wide Linearity LC-MS/MS Method for Oxylipin Quantification in Multiple Biological Samples5
HDL Meets Triglyceride5
Loss of plasma membrane lipid asymmetry can induce ordered domain (raft) formation5
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Modification in mitochondrial function is associated with the FADS1 variant and its interaction with alpha-linolenic acid-enriched diet—An exploratory study5
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Pulmonary surfactant protein B carried by HDL predicts incident CVD in patients with type 1 diabetes5
Cholesterol sulfate fluidizes the sterol fraction of the stratum corneum lipid phase and increases its permeability5
Deducing formation routes of oxylipins by quantitative multiple heart-cutting achiral-chiral 2D-LC-MS5
Analysis of omega-3 and omega-6 polyunsaturated fatty acid metabolism by compound-specific isotope analysis in humans5
Gly-β-MCA is a potent anti-cholestasis agent against “human-like” hydrophobic bile acid-induced biliary injury in mice5
1-Deoxysphingolipid synthesis compromises anchorage-independent growth and plasma membrane endocytosis in cancer cells5
Modeling enzyme competition in eicosanoid metabolism in macrophage cells using a cybernetic framework5
Serum opacity factor normalizes erythrocyte morphology in Scarb1−/− mice in an HDL-free cholesterol-dependent way5
Wide-scope targeted analysis of bioactive lipids in human plasma by LC/MS/MS4
Oxidized phospholipids cause changes in jejunum mucus that induce dysbiosis and systemic inflammation4
Identification of a Feed-Forward Loop Between 15(S)-HETE and PGE2 in Human Amnion at Parturition4
Exogenous oxygen is required for prostanoid induction under brain ischemia as evidence for a novel regulatory mechanism4
Dysregulated ceramide metabolism in mouse progressive dermatitis resulting from constitutive activation of Jak14
Uterine prostaglandin DP receptor-induced upon implantation contributes to decidualization together with EP4 receptor4
Ceramide Analysis in Combination With Genetic Testing May Provide a Precise Diagnosis for Self-Healing Collodion Babies4
MUSTN1 and FABP3 interact to regulate adipogenesis and lipid deposition4
Isomerization of bis(monoacylglycero)phosphate by acyl migration4
Selective measurement of NAPE-PLD activity via a PLA1/2-resistant fluorogenic N-acyl-phosphatidylethanolamine analog4
Sphingolipid profiling reveals differential functions of sphingolipid biosynthesis isozymes of Caenorhabditis elegans4
Identification of plasma proteins binding oxidized phospholipids using pull-down proteomics and OxLDL masking assay4
SCD4 deficiency decreases cardiac steatosis and prevents cardiac remodeling in mice fed a high-fat diet4
Alterations in LDL and HDL after an ischemic stroke associated with carotid atherosclerosis are reversed after 1 year4
Phosphatidylthreonine is a procoagulant lipid detected in human blood and elevated in coronary artery disease4
Apolipoprotein A1 deficiency increases macrophage apoptosis and necrotic core development in atherosclerotic plaques in a Bim-dependent manner4
Resolvin D2/GPR 18 axis ameliorates pressure overload-induced heart failure by inhibiting pro-inflammatory macrophage polarization4
Deletion of hepatic small heterodimer partner ameliorates development of nonalcoholic steatohepatitis in mice4
Stromal cell-derived NGF controls sympathetic innervation in subcutaneous fat4
Corrigendum: PCSK9 is not secreted from mature differentiated intestinal cells4
A high-throughput platform for the rapid screening of vitamin D status by direct infusion-MS/MS4
Glycosylation of ceramide synthase 6 is required for its activity4
CD14loCD301b+ macrophages gathering as a proangiogenic marker in adipose tissues4
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A sterol panel for rare lipid disorders: sitosterolemia, cerebrotendinous xanthomatosis and Smith-Lemli-Opitz syndrome4
Novel odd-chain cyclopropane fatty acids: detection in a mammalian lipidome and uptake by hepatosplanchnic tissues4
Type I IFN induces long-chain acyl-CoA synthetase 1 to generate a phosphatidic acid reservoir for lipotoxic saturated fatty acids4
A simple, highly sensitive, and facile method to quantify ceramide at the plasma membrane3
The oxidized phospholipid PGPC impairs endothelial function by promoting endothelial cell ferroptosis via FABP33
Novel 13C enrichment technique reveals early turnover of DHA in peripheral tissues3
Cellular cholesterol loss by DHCR24 knockdown leads to Aβ production by changing APP intracellular localization3
Lipoprotein(a) and diet: consuming sugar-sweetened beverages lowers lipoprotein(a) levels in obese and overweight adults3
Identification of genetic drivers of plasma lipoprotein size in the Diversity Outbred mouse population3
Apolipoprotein E-containing HDL decreases caspase-dependent apoptosis of memory regulatory T lymphocytes3
Lipid trajectories improve risk models for Alzheimer’s disease and mild cognitive impairment3
The lipogenic enzyme acetoacetyl-CoA synthetase and ketone body utilization for denovo lipid synthesis, a review3
The reaction specificity of mammalian ALOX15B orthologs does not depend on the evolutionary ranking of the animals3
ApoB100 remodeling and stiffened cholesteryl ester core raise LDL aggregation in familial hypercholesterolemia patients3
Evaluation of antisense oligonucleotide therapy targeting Hsd17b13 in a fibrosis mice model3
Development of a monoclonal antibody to study MARCH6, an E3 ligase that regulates proteins that control lipid homeostasis3
Whole-exome sequencing reveals damaging gene variants associated with hypoalphalipoproteinemia3
Deep generative models of LDLR protein structure to predict variant pathogenicity3
Alveolar macrophage lipid burden correlates with clinical improvement in patients with pulmonary alveolar proteinosis3
Impaired intestinal free fatty acid transport followed by chylomicron malformation, not pancreatic insufficiency, cause metabolic defects in cystic fibrosis3
Diacylglycerol kinase-ε is S-palmitoylated on cysteine in the cytoplasmic end of its N-terminal transmembrane fragment3
An anti-ANGPTL3/8 antibody decreases circulating triglycerides by binding to a LPL-inhibitory leucine zipper-like motif3
ω-O-Acylceramides but not ω-hydroxy ceramides are required for healthy lamellar phase architecture of skin barrier lipids3
Comparison of the capillary and venous blood plasma lipidomes: validation of self-collected blood for plasma lipidomics3
Multilayer regulation of postprandial triglyceride metabolism in response to acute cold exposure3
Lipoxin A4 yields an electrophilic 15-oxo metabolite that mediates FPR2 receptor-independent anti-inflammatory signaling3
Library screening identifies commercial drugs as potential structure correctors of abnormal apolipoprotein A-I3
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