OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Investigative Dermatology is 39. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Treatment of Advanced Melanoma in 2020 and Beyond	215
Connective Tissue and Fibroblast Senescence in Skin Aging	132
Environmentally-Induced (Extrinsic) Skin Aging: Exposomal Factors and Underlying Mechanisms	110
Inflammaging and the Skin	109
Cellular Senescence and the Senescence-Associated Secretory Phenotype as Drivers of Skin Photoaging	107
Differential Changes in Inflammatory Mononuclear Phagocyte and T-Cell Profiles within Psoriatic Skin during Treatment with Guselkumab vs. Secukinumab	80
High Expression of ACE2 on Keratinocytes Reveals Skin as a Potential Target for SARS-CoV-2	79
Human Dermal Fibroblast Subpopulations Are Conserved across Single-Cell RNA Sequencing Studies	74
TYK2/JAK1 Inhibitor PF-06700841 in Patients with Plaque Psoriasis: Phase IIa, Randomized, Double-Blind, Placebo-Controlled Trial	70
T Helper 2 IL-4/IL-13 Dual Blockade with Dupilumab Is Linked to Some Emergent T Helper 17‒Type Diseases, Including Seronegative Arthritis and Enthesitis/Enthesopathy, but Not to Humoral Autoimmune Dis	69
Single-Cell RNA-Sequencing Reveals Lineage-Specific Regulatory Changes of Fibroblasts and Vascular Endothelial Cells in Keloids	64
Enhanced Inflammasome Activity in Patients with Psoriasis Promotes Systemic Inflammation	63
TGFβ Signaling in Photoaging and UV-Induced Skin Cancer	61
Prurigo Nodularis Is Characterized by Systemic and Cutaneous T Helper 22 Immune Polarization	59
Mouse Models of Psoriasis: A Comprehensive Review	57
MRGPRX2 Activation Causes Increased Skin Reactivity in Patients with Chronic Spontaneous Urticaria	54
miR-19a/b and miR-20a Promote Wound Healing by Regulating the Inflammatory Response of Keratinocytes	52
Induction of Regulatory T Cells and Correction of Cytokine Disbalance by Short-Chain Fatty Acids: Implications for Psoriasis Therapy	50
Hypoxia and HIF-1α Regulate Collagen Production in Keloids	48
CAMKK2 Defines Ferroptosis Sensitivity of Melanoma Cells by Regulating AMPK‒NRF2 Pathway	48
Early and Long-Term Effects of Dupilumab Treatment on Circulating T-Cell Functions in Patients with Moderate-to-Severe Atopic Dermatitis	48
A Systematic Review of Promising Therapeutic Targets in Hidradenitis Suppurativa: A Critical Evaluation of Mechanistic and Clinical Relevance	48
EZH2 Cooperates with DNA Methylation to Downregulate Key Tumor Suppressors and IFN Gene Signatures in Melanoma	47
CYP1A1 Enzymatic Activity Influences Skin Inflammation Via Regulation of the AHR Pathway	46
Comparison of Three Diagnostic Frameworks for Pyoderma Gangrenosum	46

Principles of the Molecular and Cellular Mechanisms of Aging	44
The Genetic Basis of Vitiligo	43
Aging-Associated Changes in the Adult Human Skin Microbiome and the Host Factors that Affect Skin Microbiome Composition	42
Epilipidomics of Senescent Dermal Fibroblasts Identify Lysophosphatidylcholines as Pleiotropic Senescence-Associated Secretory Phenotype (SASP) Factors	42
Enhanced Thermal Sensitivity of TRPV3 in Keratinocytes Underlies Heat-Induced Pruritogen Release and Pruritus in Atopic Dermatitis	42
Exosomes Derived from Epidermal Stem Cells Improve Diabetic Wound Healing	42
Altered Skin and Gut Microbiome in Hidradenitis Suppurativa	42
The Genomic Landscape of Actinic Keratosis	41
An Autocrine Circuit of IL-33 in Keratinocytes Is Involved in the Progression of Psoriasis	41
Dermal Adipose Tissue Secretes HGF to Promote Human Hair Growth and Pigmentation	40
QR-313, an Antisense Oligonucleotide, Shows Therapeutic Efficacy for Treatment of Dominant and Recessive Dystrophic Epidermolysis Bullosa: A Preclinical Study	40
Which Way Do We Go? Complex Interactions in Atopic Dermatitis Pathogenesis	40
From Empirical to Pathogenesis-Based Treatments for Psoriasis	39
In-Depth Analysis of the Hidradenitis Suppurativa Serum Proteome Identifies Distinct Inflammatory Subtypes	39
MRGPRX2 Is the Codeine Receptor of Human Skin Mast Cells: Desensitization through β-Arrestin and Lack of Correlation with the FcεRI Pathway	39