Journal of Immunology

Article	Citations
Inflammasomes and Pyroptosis as Therapeutic Targets for COVID-19	197
A Potently Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection	176
COVID-19 as an Acute Inflammatory Disease	126
COVID-19: Complement, Coagulation, and Collateral Damage	118
Cutting Edge: Nucleocapsid Vaccine Elicits Spike-Independent SARS-CoV-2 Protective Immunity	118
Cutting Edge: Severe SARS-CoV-2 Infection in Humans Is Defined by a Shift in the Serum Lipidome, Resulting in Dysregulation of Eicosanoid Immune Mediators	114
African Swine Fever Virus MGF-505-7R Negatively Regulates cGAS–STING-Mediated Signaling Pathway	99
SARS-CoV-2 Antibody Responses Are Correlated to Disease Severity in COVID-19 Convalescent Individuals	92
Function and Regulation of Noncanonical Caspase-4/5/11 Inflammasome	88
Metformin Enhances the Antitumor Activity of CD8+ T Lymphocytes via the AMPK–miR-107–Eomes–PD-1 Pathway	81
Cancer Cell–Intrinsic Expression of MHC Class II Regulates the Immune Microenvironment and Response to Anti–PD-1 Therapy in Lung Adenocarcinoma	75
Tertiary Lymphoid Structures: Diversity in Their Development, Composition, and Role	73
Mouse 4T1 Breast Cancer Cell–Derived Exosomes Induce Proinflammatory Cytokine Production in Macrophages via miR-183	71
Expansion of SARS-CoV-2–Specific Antibody-Secreting Cells and Generation of Neutralizing Antibodies in Hospitalized COVID-19 Patients	70
Zebrafish GSDMEb Cleavage-Gated Pyroptosis Drives Septic Acute Kidney Injury In Vivo	67
Cutting Edge: Circulating Exosomes with COVID Spike Protein Are Induced by BNT162b2 (Pfizer–BioNTech) Vaccination prior to Development of Antibodies: A Novel Mechanism for Immune Activation by mRNA Va	67
Antibody Responses to SARS-CoV-2: Let’s Stick to Known Knowns	67
A Case for Targeting Th17 Cells and IL-17A in SARS-CoV-2 Infections	62
Collagen Density Modulates the Immunosuppressive Functions of Macrophages	62
The Inflammatory Factors Associated with Disease Severity to Predict COVID-19 Progression	59
New Insights into the Immune System Using Dirty Mice	58
Development of a SARS-CoV-2 Total Antibody Assay and the Dynamics of Antibody Response over Time in Hospitalized and Nonhospitalized Patients with COVID-19	57
Role of Aging and the Immune Response to Respiratory Viral Infections: Potential Implications for COVID-19	57
A Transgenic Line That Reports CSF1R Protein Expression Provides a Definitive Marker for the Mouse Mononuclear Phagocyte System	57
Fc Galactosylation Promotes Hexamerization of Human IgG1, Leading to Enhanced Classical Complement Activation	56

AMP-Activated Protein Kinase Restricts Zika Virus Replication in Endothelial Cells by Potentiating Innate Antiviral Responses and Inhibiting Glycolysis	55
Endothelial Pannexin 1 Channels Control Inflammation by Regulating Intracellular Calcium	54
Microglial NLRP3 Inflammasome Activation upon TLR2 and TLR5 Ligation by Distinct α-Synuclein Assemblies	54
Salmonella Flagellin Activates NAIP/NLRC4 and Canonical NLRP3 Inflammasomes in Human Macrophages	54
Dynamic Roles for IL-2–STAT5 Signaling in Effector and Regulatory CD4+ T Cell Populations	53
African Swine Fever Virus pI215L Negatively Regulates cGAS-STING Signaling Pathway through Recruiting RNF138 to Inhibit K63-Linked Ubiquitination of TBK1	53
NOD1 Promotes Antiviral Signaling by Binding Viral RNA and Regulating the Interaction of MDA5 and MAVS	52
Preclinical Efficacy and Anti-Inflammatory Mechanisms of Action of the Bruton Tyrosine Kinase Inhibitor Rilzabrutinib for Immune-Mediated Disease	50
SARS-CoV-2 NSP13 Inhibits Type I IFN Production by Degradation of TBK1 via p62-Dependent Selective Autophagy	50
PANoptosis: A Unique Innate Immune Inflammatory Cell Death Modality	50
Malat1 Suppresses Immunity to Infection through Promoting Expression of Maf and IL-10 in Th Cells	49
Genome-Wide B Cell, CD4+, and CD8+ T Cell Epitopes That Are Highly Conserved between Human and Animal Coronaviruses, Identified from SARS-CoV-2 as Targets for Preemptive Pan-Coronavirus Vaccines	49
Depletion of NK Cells Improves Cognitive Function in the Alzheimer Disease Mouse Model	48
IL-1 Receptor Antagonist Anakinra in the Treatment of COVID-19 Acute Respiratory Distress Syndrome: A Retrospective, Observational Study	48
Asah2 Represses the p53–Hmox1 Axis to Protect Myeloid-Derived Suppressor Cells from Ferroptosis	48
Neutrophil Extracellular Trap–Associated CEACAM1 as a Putative Therapeutic Target to Prevent Metastatic Progression of Colon Carcinoma	48
Early Insights into Immune Responses during COVID-19	47
Insights into the Mechanism of Action of Highly Diluted Biologics	47
OTUD1 Negatively Regulates Type I IFN Induction by Disrupting Noncanonical Ubiquitination of IRF3	46
The Butyrate-Producing Bacterium Clostridium butyricum Suppresses Clostridioides difficile Infection via Neutrophil- and Antimicrobial Cytokine–Dependent but GPR43/109a-Independent Mecha	46
Galectin-9 and VISTA Expression Define Terminally Exhausted T Cells in HIV-1 Infection	45
Translating JAKs to Jakinibs	44
Interplay between RAGE and TLR4 Regulates HMGB1-Induced Inflammation by Promoting Cell Surface Expression of RAGE and TLR4	43
AKT Regulates NLRP3 Inflammasome Activation by Phosphorylating NLRP3 Serine 5	42
Low Vitamin D Status Is Associated with Inflammation in Patients with Chronic Obstructive Pulmonary Disease	41
Soluble Uric Acid Is an Intrinsic Negative Regulator of Monocyte Activation in Monosodium Urate Crystal–Induced Tissue Inflammation	41
TGF-β and IL-15 Synergize through MAPK Pathways to Drive the Conversion of Human NK Cells to an Innate Lymphoid Cell 1–like Phenotype	41
KLRG1+ Memory CD8 T Cells Combine Properties of Short-Lived Effectors and Long-Lived Memory	40
IL-10 Dampens an IL-17–Mediated Periodontitis-Associated Inflammatory Network	40
HMGB1-Mediated Neutrophil Extracellular Trap Formation Exacerbates Intestinal Ischemia/Reperfusion-Induced Acute Lung Injury	40
Inducible MicroRNA-217 Inhibits NF-κB– and IRF3-Driven Immune Responses in Lower Vertebrates through Targeting TAK1	40
Human Term Pregnancy Decidual NK Cells Generate Distinct Cytotoxic Responses	40
Development and Immunological Function of Lymph Node Stromal Cells	40
IFN Regulatory Factor 3 in Health and Disease	39
Sex Differences in Macrophage Responses to Obesity-Mediated Changes Determine Migratory and Inflammatory Traits	38
Tuning Macrophage Phenotype to Mitigate Skeletal Muscle Fibrosis	38
Nanoparticles Displaying Allergen and Siglec-8 Ligands Suppress IgE-FcεRI–Mediated Anaphylaxis and Desensitize Mast Cells to Subsequent Antigen Challenge	38
SLAMF7 Signaling Reprograms T Cells toward Exhaustion in the Tumor Microenvironment	38
Dendritic Cell Maturation Defines Immunological Responsiveness of Tumors to Radiation Therapy	37
Regulatory T Cells in Angiogenesis	37
Novel SIRPα Antibodies That Induce Single-Agent Phagocytosis of Tumor Cells while Preserving T Cells	37
C5aR2 Activation Broadly Modulates the Signaling and Function of Primary Human Macrophages	37
TCR Signal Strength and Antigen Affinity Regulate CD8+ Memory T Cells	37
Triggering of the cGAS–STING Pathway in Human Plasmacytoid Dendritic Cells Inhibits TLR9-Mediated IFN Production	37
Biomarkers for Predicting Cytokine Release Syndrome following CD19-Targeted CAR T Cell Therapy	36
Neutrophils Recirculate through Lymph Nodes to Survey Tissues for Pathogens	36
Regulation of the NLRP3 Inflammasome by Posttranslational Modifications	36
Zebrafish IL-4–like Cytokines and IL-10 Suppress Inflammation but Only IL-10 Is Essential for Gill Homeostasis	36
Porphyromonas gingivalis Promotes Immunoevasion of Oral Cancer by Protecting Cancer from Macrophage Attack	36
Influenza Suppresses Neutrophil Recruitment to the Lung and Exacerbates Secondary Invasive Pulmonary Aspergillosis	36

Focused Ultrasound for Immunomodulation of the Tumor Microenvironment	36
Efficient CRISPR/Cas9 Gene Editing in Uncultured Naive Mouse T Cells for In Vivo Studies	35
Prevailing Role of Mucosal Igs and B Cells in Teleost Skin Immune Responses to Bacterial Infection	35
Cutting Edge: Mouse SARS-CoV-2 Epitope Reveals Infection and Vaccine-Elicited CD8 T Cell Responses	35
TRIM14 Is a Key Regulator of the Type I IFN Response during Mycobacterium tuberculosis Infection	35
Cancer-Associated Fibroblasts and T Cells: From Mechanisms to Outcomes	35
Long Noncoding RNA AW112010 Promotes the Differentiation of Inflammatory T Cells by Suppressing IL-10 Expression through Histone Demethylation	34
A 2020 View of Thymus Stromal Cells in T Cell Development	34
Zhx2 Accelerates Sepsis by Promoting Macrophage Glycolysis via Pfkfb3	34
Hyperglycemic Memory of Innate Immune Cells Promotes In Vitro Proinflammatory Responses of Human Monocytes and Murine Macrophages	34
Cutting Edge: Characterization of Human Tissue-Resident Memory T Cells at Different Infection Sites in Patients with Tuberculosis	34
Combination of Fruquintinib and Anti–PD-1 for the Treatment of Colorectal Cancer	34
Anti-Inflammatory and Proresolving Effects of the Omega-6 Polyunsaturated Fatty Acid Adrenic Acid	33
Influenza Infection Induces Alveolar Macrophage Dysfunction and Thereby Enables Noninvasive Streptococcus pneumoniae to Cause Deadly Pneumonia	33
TNF-α and IL-10 Control CXCL13 Expression in Human Macrophages	33
Genetic, Immunological, and Clinical Features of 32 Patients with Autosomal Recessive STAT1 Deficiency	33
TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide–HLA Complex	33
HLA-DR Marks Recently Divided Antigen-Specific Effector CD4 T Cells in Active Tuberculosis Patients	32
The Quality of SARS-CoV-2–Specific T Cell Functions Differs in Patients with Mild/Moderate versus Severe Disease, and T Cells Expressing Coinhibitory Receptors Are Highly Activated	32
Reinvestigation of Classic T Cell Subsets and Identification of Novel Cell Subpopulations by Single-Cell RNA Sequencing	32
TNF-α Regulates Human Plasmacytoid Dendritic Cells by Suppressing IFN-α Production and Enhancing T Cell Activation	32
Affinity Maturation of B7-H6 Translates into Enhanced NK Cell–Mediated Tumor Cell Lysis and Improved Proinflammatory Cytokine Release of Bispecific Immunoligands via NKp30 Engagement	32
Single-Cell Analysis Reveals the Range of Transcriptional States of Circulating Human Neutrophils	32
Naive- and Memory-like CD21low B Cell Subsets Share Core Phenotypic and Signaling Characteristics in Systemic Autoimmune Disorders	31
Human Gut Commensal Membrane Vesicles Modulate Inflammation by Generating M2-like Macrophages and Myeloid-Derived Suppressor Cells	31
CD11c+ T-bet+ B Cells Require IL-21 and IFN-γ from Type 1 T Follicular Helper Cells and Intrinsic Bcl-6 Expression but Develop Normally in the Absence of T-bet	31
γδ T Cells Kill Plasmodium falciparum in a Granzyme- and Granulysin-Dependent Mechanism during the Late Blood Stage	31
A Critical Role for the CXCL3/CXCL5/CXCR2 Neutrophilic Chemotactic Axis in the Regulation of Type 2 Responses in a Model of Rhinoviral-Induced Asthma Exacerbation	31
Baby’s First Macrophage: Temporal Regulation of Hofbauer Cell Phenotype Influences Ligand-Mediated Innate Immune Responses across Gestation	31
Leishmania donovani Subverts Host Immune Response by Epigenetic Reprogramming of Macrophage M(Lipopolysaccharides + IFN-γ)/M(IL-10) Polarization	30
Damage-Associated Molecular Patterns and the Systemic Immune Consequences of Severe Thermal Injury	30
Chemokine Signatures of Pathogen-Specific T Cells I: Effector T Cells	30
Airway Macrophages Mediate Mucosal Vaccine–Induced Trained Innate Immunity against Mycobacterium tuberculosis in Early Stages of Infection	30
Gut Microbiota Regulate Gut–Lung Axis Inflammatory Responses by Mediating ILC2 Compartmental Migration	29
The Ugly Duckling Turned to Swan: A Change in Perception of Bystander-Activated Memory CD8 T Cells	29
Regulation and Role of αE Integrin and Gut Homing Integrins in Migration and Retention of Intestinal Lymphocytes during Inflammatory Bowel Disease	29
Regulatory T Cells Induced by Single-Peptide Liposome Immunotherapy Suppress Islet-Specific T Cell Responses to Multiple Antigens and Protect from Autoimmune Diabetes	29
SARS-CoV-2 Neutralizing Antibody Responses towards Full-Length Spike Protein and the Receptor-Binding Domain	29
Transcriptomic Profiling Identifies CD8+ T Cells in the Brain of Aged and Alzheimer’s Disease Transgenic Mice as Tissue-Resident Memory T Cells	28
A Defect in Thymic Tolerance Causes T Cell–Mediated Autoimmunity in a Murine Model of COPA Syndrome	28
Middle East Respiratory Syndrome Coronavirus ORF8b Accessory Protein Suppresses Type I IFN Expression by Impeding HSP70-Dependent Activation of IRF3 Kinase IKKε	28
Pyroptosis Mediates Neutrophil Extracellular Trap Formation during Bacterial Infection in Zebrafish	28
Seneca Valley Virus 3C Protease Induces Pyroptosis by Directly Cleaving Porcine Gasdermin D	28
IL-6 Deficiency Exacerbates Allergic Asthma and Abrogates the Protective Effect of Allergic Inflammation against Streptococcus pneumoniae Pathogenesis	28
β-Glucan Induces Distinct and Protective Innate Immune Memory in Differentiated Macrophages	28
Localized Immunomodulation with PD-L1 Results in Sustained Survival and Function of Allogeneic Islets without Chronic Immunosuppression	27
Broad-Spectrum Robust Direct Bactericidal Activity of Fish IFNφ1 Reveals an Antimicrobial Peptide–like Function for Type I IFNs in Vertebrates	27
A Comprehensive Workflow for Applying Single-Cell Clustering and Pseudotime Analysis to Flow Cytometry Data	27
IL-10 as a Th2 Cytokine: Differences Between Mice and Humans	27
Serum- and Glucocorticoid-Inducible Kinase 1 Promotes Alternative Macrophage Polarization and Restrains Inflammation through FoxO1 and STAT3 Signaling	27
Beyond Good and Evil: Molecular Mechanisms of Type I and III IFN Functions	27
Afferent Lymphatic Transport and Peripheral Tissue Immunity	27
Porcine Epidemic Diarrhea Virus Membrane Protein Interacted with IRF7 to Inhibit Type I IFN Production during Viral Infection	26
Cutting Edge: Distinct B Cell Repertoires Characterize Patients with Mild and Severe COVID-19	26
The Expression of P2X7 Receptor on Th1, Th17, and Regulatory T Cells in Patients with Systemic Lupus Erythematosus or Rheumatoid Arthritis and Its Correlations with Active Disease	26
NLRP3 Inflammasome Activation in Lung Vascular Endothelial Cells Contributes to Intestinal Ischemia/Reperfusion-Induced Acute Lung Injury	26
Systematic Examination of Antigen-Specific Recall T Cell Responses to SARS-CoV-2 versus Influenza Virus Reveals a Distinct Inflammatory Profile	26
Complex Autoantibody Responses Occur following Moderate to Severe Traumatic Brain Injury	26
Targeting Antigens to Different Receptors on Conventional Type 1 Dendritic Cells Impacts the Immune Response	26
A MicroRNA-1–Mediated Inhibition of the NF-κB Pathway by the JAK-STAT Pathway in the Invertebrate Litopenaeus vannamei	26
The Bile Acid Receptor GPBAR1 Modulates CCL2/CCR2 Signaling at the Liver Sinusoidal/Macrophage Interface and Reverses Acetaminophen-Induced Liver Toxicity	25
Nutritional Modulation of the Microbiome and Immune Response	25
Proinflammatory S100A8 Induces PD-L1 Expression in Macrophages, Mediating Tumor Immune Escape	25
mTORC1 Signaling Regulates Proinflammatory Macrophage Function and Metabolism	25
RORγt Promotes Foxp3 Expression by Antagonizing the Effector Program in Colonic Regulatory T Cells	25
SARS-CoV-2 Cysteine-like Protease Antibodies Can Be Detected in Serum and Saliva of COVID-19–Seropositive Individuals	25
Upregulated PKM2 in Macrophages Exacerbates Experimental Arthritis via STAT1 Signaling	25
Loss of Mitochondrial Protease CLPP Activates Type I IFN Responses through the Mitochondrial DNA–cGAS–STING Signaling Axis	25
Single-Cell Transcriptional Profiling Reveals Signatures of Helper, Effector, and Regulatory MAIT Cells during Homeostasis and Activation	25
Longitudinal Peripheral Blood Transcriptional Analysis Reveals Molecular Signatures of Disease Progression in COVID-19 Patients	25
Cutting Edge: Activation-Induced Iron Flux Controls CD4 T Cell Proliferation by Promoting Proper IL-2R Signaling and Mitochondrial Function	25
Efficient Expansion of Human Granzyme B–Expressing B Cells with Potent Regulatory Properties	25
IL-1R Regulates Disease Tolerance and Cachexia in Toxoplasma gondii Infection	24
Cross-Talk between the Complement Pathway and the Contact Activation System of Coagulation: Activated Factor XI Neutralizes Complement Factor H	24
Metformin and 2-Deoxyglucose Collaboratively Suppress Human CD4+ T Cell Effector Functions and Activation-Induced Metabolic Reprogramming	24
GPA33: A Marker to Identify Stable Human Regulatory T Cells	24
Network Analysis Reveals a Distinct Axis of Macrophage Activation in Response to Conflicting Inflammatory Cues	24
Cutting Edge: Batf3 Expression by CD8 T Cells Critically Regulates the Development of Memory Populations	24
Enhanced Proliferation of Ly6C+ Monocytes/Macrophages Contributes to Chronic Inflammation in Skin Wounds of Diabetic Mice	24
In Primitive Zebrafish, MHC Class II Expression Is Regulated by IFN-γ, IRF1, and Two Forms of CIITA	24

Serotonin (5-HT) Shapes the Macrophage Gene Profile through the 5-HT2B–Dependent Activation of the Aryl Hydrocarbon Receptor	24
Multibatch Cytometry Data Integration for Optimal Immunophenotyping	23
Innate Immune Memory and the Host Response to Infection	23
Activation of the Tec Kinase ITK Controls Graded IRF4 Expression in Response to Variations in TCR Signal Strength	23
Human CD8+ T Cells Exhibit a Shared Antigen Threshold for Different Effector Responses	23
RNA-Binding Protein HuR Promotes Th17 Cell Differentiation and Can Be Targeted to Reduce Autoimmune Neuroinflammation	23
The Regulatory Subunit PPP2R2A of PP2A Enhances Th1 and Th17 Differentiation through Activation of the GEF-H1/RhoA/ROCK Signaling Pathway	23
Cytomegalovirus Coinfection Is Associated with Increased Vascular-Homing CD57+ CD4 T Cells in HIV Infection	23
Integration of the Transcriptome and Genome-Wide Landscape of BRD2 and BRD4 Binding Motifs Identifies Key Superenhancer Genes and Reveals the Mechanism of Bet Inhibitor Action in Rheumatoid Arthritis	23
E3 Ubiquitin Ligase RNF114 Inhibits Innate Immune Response to Red-Spotted Grouper Nervous Necrosis Virus Infection in Sea Perch by Targeting MAVS and TRAF3 to Mediate Their Degradation	23
Redistribution of Monocyte Subsets in Obstructive Sleep Apnea Syndrome Patients Leads to an Imbalanced PD-1/PD-L1 Cross-Talk with CD4/CD8 T Cells	23
Extracellular ATP Augments Antigen-Induced Murine Mast Cell Degranulation and Allergic Responses via P2X4 Receptor Activation	23
Immunopeptidome Analysis of HLA-DPB1 Allelic Variants Reveals New Functional Hierarchies	23
Encephalitogenic and Regulatory CD8 T Cells in Multiple Sclerosis and Its Animal Models	22
Helminth Imprinting of Hematopoietic Stem Cells Sustains Anti-Inflammatory Trained Innate Immunity That Attenuates Autoimmune Disease	22
Neonatal and Children’s Immune System and COVID-19: Biased Immune Tolerance versus Resistance Strategy	22
Critical Role of Zinc Transporter (ZIP8) in Myeloid Innate Immune Cell Function and the Host Response against Bacterial Pneumonia	22
Small-Molecule Inhibitor of 8-Oxoguanine DNA Glycosylase 1 Regulates Inflammatory Responses during Pseudomonas aeruginosa Infection	22
Characterization of the SARS-CoV-2 Neutralization Potential of COVID-19–Convalescent Donors	22
C-Type Lectin Maintains the Homeostasis of Intestinal Microbiota and Mediates Biofilm Formation by Intestinal Bacteria in Shrimp	22
Exosomal miRNA-19a and miRNA-614 Induced by Air Pollutants Promote Proinflammatory M1 Macrophage Polarization via Regulation of RORα Expression in Human Respiratory Mucosal Microenvironment	21
CD29 Enriches for Cytotoxic Human CD4+ T Cells	21
CXCL20a, a Teleost-Specific Chemokine That Orchestrates Direct Bactericidal, Chemotactic, and Phagocytosis-Killing–Promoting Functions, Contributes to Clearance of Bacterial Infections	21
Simultaneous Aerosol and Intramuscular Immunization with Influenza Vaccine Induces Powerful Protective Local T Cell and Systemic Antibody Immune Responses in Pigs	21
Maternal T Cells in the Human Placental Villi Support an Allograft Response during Noninfectious Villitis	21
Self RNA Sensing by RIG-I–like Receptors in Viral Infection and Sterile Inflammation	21
Comprehensive Immunologic Evaluation of Bronchoalveolar Lavage Samples from Human Patients with Moderate and Severe Seasonal Influenza and Severe COVID-19	21
Mannose-Binding Lectin Possesses Agglutination Activity and Promotes Opsonophagocytosis of Macrophages with Calreticulin Interaction in an Early Vertebrate	21
Radiation-Induced Macrophage Senescence Impairs Resolution Programs and Drives Cardiovascular Inflammation	21
ERAP1 Controls the Autoimmune Response against Melanocytes in Psoriasis by Generating the Melanocyte Autoantigen and Regulating Its Amount for HLA-C*06:02 Presentation	21
CCL17 in Inflammation and Pain	21
Macrophagic Extracellular Vesicle CXCL2 Recruits and Activates the Neutrophil CXCR2/PKC/NOX4 Axis in Sepsis	21
NK Cell–Derived IL-10 Supports Host Survival during Sepsis	21
Fermentable Dietary Fiber Promotes Helminth Infection and Exacerbates Host Inflammatory Responses	21
A Whole Blood Enzyme-Linked Immunospot Assay for Functional Immune Endotyping of Septic Patients	20
Adoptive T Cell Therapy with IL-12–Preconditioned Low-Avidity T Cells Prevents Exhaustion and Results in Enhanced T Cell Activation, Enhanced Tumor Clearance, and Decreased Risk for Autoimmunity	20
Discordance between Serum Neutralizing Antibody Titers and the Recovery from COVID-19	20
Complement as Prognostic Biomarker and Potential Therapeutic Target in Renal Cell Carcinoma	20
Herpes Simplex Virus Type 2 Inhibits Type I IFN Signaling Mediated by the Novel E3 Ubiquitin Protein Ligase Activity of Viral Protein ICP22	20
Metabolomic Profiles in the Intestine of Shrimp Infected by White Spot Syndrome Virus and Antiviral Function of the Metabolite Linoleic Acid in Shrimp	20
Apolipoprotein E Triggers Complement Activation in Joint Synovial Fluid of Rheumatoid Arthritis Patients by Binding C1q	20
Development of an Optimized Culture System for Generating Mouse Alveolar Macrophage–like Cells	20
Zika Virus–Infected Decidual Cells Elicit a Gestational Age–Dependent Innate Immune Response and Exaggerate Trophoblast Zika Permissiveness: Implication for Vertical Transmission	20
Display of Native Antigen on cDC1 That Have Spatial Access to Both T and B Cells Underlies Efficient Humoral Vaccination	20
IFN-Stimulated Gene 15 Is an Alarmin that Boosts the CTL Response via an Innate, NK Cell–Dependent Route	20
Moderate Exercise Inhibits Age-Related Inflammation, Liver Steatosis, Senescence, and Tumorigenesis	20
IgG Immune Complexes Break Immune Tolerance of Human Microglia	20
Mitochondrial Reactive Oxygen Species Participate in Signaling Triggered by Heme in Macrophages and upon Hemolysis	20
Mapping Human Monoclonal IgE Epitopes on the Major Dust Mite Allergen Der p 2	20
Phosphoflow Protocol for Signaling Studies in Human and Murine B Cell Subpopulations	20
IgA Nephropathy Benefits from Compound K Treatment by Inhibiting NF-κB/NLRP3 Inflammasome and Enhancing Autophagy and SIRT1	19
Surfactant Protein-A Protects against IL-13–Induced Inflammation in Asthma	19
Seletalisib for Activated PI3Kδ Syndromes: Open-Label Phase 1b and Extension Studies	19
Complement Receptor 3 Forms a Compact High-Affinity Complex with iC3b	19
Establishment of a Pig Influenza Challenge Model for Evaluation of Monoclonal Antibody Delivery Platforms	19
Analysis of Gene Expression and TCR/B Cell Receptor Profiling of Immune Cells in Primary Sjögren’s Syndrome by Single-Cell Sequencing	19
TRAF3 Acts as a Checkpoint of B Cell Receptor Signaling to Control Antibody Class Switch Recombination and Anergy	19
CARD9-Associated Dectin-1 and Dectin-2 Are Required for Protective Immunity of a Multivalent Vaccine against Coccidioides posadasii Infection	19
Zebrafish F-box Protein fbxo3 Negatively Regulates Antiviral Response through Promoting K27-Linked Polyubiquitination of the Transcription Factors irf3 and irf7	19
Murine Glucocorticoid Receptors Orchestrate B Cell Migration Selectively between Bone Marrow and Blood	19
Engineering Human MAIT Cells with Chimeric Antigen Receptors for Cancer Immunotherapy	19
Exon–Intron Circular RNA circRNF217 Promotes Innate Immunity and Antibacterial Activity in Teleost Fish by Reducing miR-130-3p Function	19
Autoreactivity of Peripheral Helper T Cells in the Joints of Rheumatoid Arthritis	19
Dengue Virus Degrades USP33–ATF3 Axis via Extracellular Vesicles to Activate Human Microglial Cells	19
Noncanonical Roles of Caspase-4 and Caspase-5 in Heme-Driven IL-1β Release and Cell Death	19
Identification and Characterization of Zebrafish Tlr4 Coreceptor Md-2	19
B Lymphocyte–Derived CCL7 Augments Neutrophil and Monocyte Recruitment, Exacerbating Acute Kidney Injury	19
Homeostatic Milieu Induces Production of Deoxyribonuclease 1–like 3 from Myeloid Cells	19
Epigenetic Regulation of TLR4 in Diabetic Macrophages Modulates Immunometabolism and Wound Repair	19
Features of B Cell Responses Relevant to Allergic Disease	18
IRF8 Regulates Gram-Negative Bacteria–Mediated NLRP3 Inflammasome Activation and Cell Death	18
G3BP1 Inhibition Alleviates Intracellular Nucleic Acid–Induced Autoimmune Responses	18
Kdm6b Regulates the Generation of Effector CD8+ T Cells by Inducing Chromatin Accessibility in Effector-Associated Genes	18
Comparative Analysis of Antigen-Specific Anti–SARS-CoV-2 Antibody Isotypes in COVID-19 Patients	18
Leptin Augments Antitumor Immunity in Obesity by Repolarizing Tumor-Associated Macrophages	18
Peptide Binding to HLA-E Molecules in Humans, Nonhuman Primates, and Mice Reveals Unique Binding Peptides but Remarkably Conserved Anchor Residues	18
Regulatory T Cells Limit Pneumococcus-Induced Exacerbation of Lung Fibrosis in Mice	18
Systematic Profiling of Full-Length Ig and TCR Repertoire Diversity in Rhesus Macaque through Long Read Transcriptome Sequencing	18
A Critical Role of CD40 and CD70 Signaling in Conventional Type 1 Dendritic Cells in Expansion and Antitumor Efficacy of Adoptively Transferred Tumor-Specific T Cells	18
AMPKα1 in B Cells Dampens Primary Antibody Responses yet Promotes Mitochondrial Homeostasis and Persistence of B Cell Memory	18
Fewer LAG-3+ T Cells in Relapsing-Remitting Multiple Sclerosis and Type 1 Diabetes	18
COX Inhibition Increases Alternaria-Induced Pulmonary Group 2 Innate Lymphoid Cell Responses and IL-33 Release in Mice	18
Mettl14-Mediated m6A Modification Is Essential for Germinal Center B Cell Response	18
Selective Inhibition of the Interaction between SARS-CoV-2 Spike S1 and ACE2 by SPIDAR Peptide Induces Anti-Inflammatory Therapeutic Responses	18
Differential Effects of Myeloid Cell PPARδ and IL-10 in Regulating Macrophage Recruitment, Phenotype, and Regeneration following Acute Muscle Injury	18
Chaperone-Mediated Autophagy Suppresses Apoptosis via Regulation of the Unfolded Protein Response during Chronic Obstructive Pulmonary Disease Pathogenesis	18
Bidirectional Transport of IgE by CD23 in the Inner Ear of Patients with Meniere’s Disease	18
Lipopolysaccharide Induces GFAT2 Expression to Promote O-Linked β-N-Acetylglucosaminylation and Attenuate Inflammation in Macrophages	18
Identification of a T-bethi Quiescent Exhausted CD8 T Cell Subpopulation That Can Differentiate into TIM3+CX3CR1+ Effectors and Memory-like Cells	18
Human Cord Blood B Cells Differ from the Adult Counterpart by Conserved Ig Repertoires and Accelerated Response Dynamics	18
A Novel Fusion of IL-10 Engineered to Traffic across Intestinal Epithelium to Treat Colitis	18
N-Glycan Branching Is Required for Development of Mature B Cells	18
An Alternative Splicing of Tupaia STING Modulated Anti-RNA Virus Responses by Targeting MDA5-LGP2 and IRF3	18
SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity	18
MicroRNA-21 Deficiency Promotes the Early Th1 Immune Response and Resistance toward Visceral Leishmaniasis	17