OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Experimental Medicine is 56. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Primary tumor–derived systemic nANGPTL4 inhibits metastasis	265
SARS-CoV-2 Spike protein suppresses CTL-mediated killing by inhibiting immune synapse assembly	159
The pathogenic role of retinoid nuclear receptor signaling in cancer and metabolic syndromes	140
Intestinal epithelial c-Maf expression determines enterocyte differentiation and nutrient uptake in mice	140
IL-21 shapes germinal center polarization via light zone B cell selection and cyclin D3 upregulation	127
Antibody feedback contributes to facilitating the development of Omicron-reactive memory B cells in SARS-CoV-2 mRNA vaccinees	121
B cell receptor ligation induces IgE plasma cell elimination	121
An iron-rich subset of macrophages promotes tumor growth through a Bach1-Ednrb axis	120
Familial pulmonary alveolar proteinosis and type I interferonopathy by mutation of STAT2 (TIMS2)	117
RORγt eTACs mediate oral tolerance and Treg induction	116
Leveraging cDC1 biology and function for enhanced immunotherapy	113
Epitope and HLA specificity of human TCRs against Plasmodium falciparum circumsporozoite protein	108
Local gene editing of fibroblasts in tumors reveals a new cancer-associated fibroblast state	103
ALK2/3 recruitment to the immunological synapse is required for T cell activation and death	103
Host factor TIMP1 sustains long-lasting myeloid-biased hematopoiesis after severe infection	102
Early innate role for CD8αα+ cells in tuberculosis	101
Common cold embecovirus imprinting primes broadly neutralizing antibody responses to SARS-CoV-2 S2	98
S1PR1, an endothelial-immune influencer	98
Prenatally derived macrophages support choroidal health and decline in age-related macular degeneration	92
Antigen-independent, autonomous B cell receptor signaling drives activated B cell DLBCL	91
High burden of viruses and bacterial pathobionts drives heightened nasal innate immunity in children	91
Correction: Segmented filamentous bacteria–induced epithelial MHCII regulates cognate CD4+ IELs and epithelial turnover	90
Correction: ICAM-1 controls development and function of ILC2	90
Transit-amplifying cells control R-spondins in the mouse crypt to modulate intestinal stem cell proliferation	90
Lymphatic chain gradients regulate the magnitude and heterogeneity of T cell responses to vaccination	88

Challenges in TB research	88
NFAT5 governs cellular plasticity-driven resistance to KRAS-targeted therapy in pancreatic cancer	86
T cell engagers emerge as a compelling therapeutic modality	86
TIGIT mediates activation-induced cell death of ILC2s during chronic airway allergy	86
CXCL12+ dermal fibroblasts promote neutrophil recruitment and host defense by recognition of IL-17	82
IFNγ score–based neoadjuvant immunotherapy for stage III melanoma	81
Heterozygous human JAK2V617F activates AhR to drive essential thrombocythemia and promote thrombosis	79
Obesity alters monocyte developmental trajectories to enhance metastasis	79
Non-professional efferocytosis of Salmonella -infected intestinal epithelial cells in the neonatal host	78
Correction: CD55 regulates self-renewal and cisplatin resistance in endometrioid tumors	77
The genetic background shapes the susceptibility to mitochondrial dysfunction and NASH progression	75
CD8+ T cell depletion prevents neuropathology in a mouse model of globoid cell leukodystrophy	72
Interferon-λ drives renal fibrosis by coordinating epithelial–fibroblast crosstalk	72
A human STAT3 gain-of-function variant drives local Th17 dysregulation and skin inflammation in mice	72
Loss of ATG7 in microglia impairs UPR, triggers ferroptosis, and weakens amyloid pathology control	69
pDCs, type 1 IFN, and the female predileXion of SSc	69
Dual role of vascular endothelial growth factor-C in post-stroke recovery	68
Michelle Linterman: We are always learning	67
How decreasing T cell signaling unexpectedly results in autoimmunity	67
Nina Cabezas Wallscheid: Enjoying the freedom to decide my research path	66
Memory B cell responses to Omicron subvariants after SARS-CoV-2 mRNA breakthrough infection in humans	62
Deficiency for SAMHD1 activates MDA5 in a cGAS/STING-dependent manner	61
Addendum: RAF/MEK/extracellular signal–related kinase pathway suppresses dendritic cell migration and traps dendritic cells in Langerhans cell histiocytosis lesions	60
Augmenting neurogenesis rescues memory impairments in Alzheimer’s disease by restoring the memory-storing neurons	60
eIF3e-mediated translational checkpoint maintains immune tolerance and prevents lymphoid malignancy	59
Rethinking disomy: Autosomal expression bias	58
Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses	58
IEC-intrinsic IL-1R signaling holds dual roles in regulating intestinal homeostasis and inflammation	58
Immunomolecular and reactivity landscapes of gut IgA subclasses in homeostasis and inflammatory bowel disease	57
PRECISE-seq reveals disease-relevant TCR repertoires with phenotypic plasticity	57
Functional specialization of short-lived and long-lived macrophage subsets in human tonsils	57
Spatiotemporal dynamics of fetal liver hematopoietic niches	56
MYO1F in neutrophils is required for the response to immune checkpoint blockade therapy	56
MYC is a clinically significant driver of mTOR inhibitor resistance in breast cancer	56