OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Experimental Medicine is 62. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Neuroinvasion of SARS-CoV-2 in human and mouse brain	655
Inflammasomes are activated in response to SARS-CoV-2 infection and are associated with COVID-19 severity in patients	576
Lipid metabolism and cancer	440
Ferroptosis in infection, inflammation, and immunity	380
Highly functional virus-specific cellular immune response in asymptomatic SARS-CoV-2 infection	270
Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo	267
Preexisting autoantibodies to type I IFNs underlie critical COVID-19 pneumonia in patients with APS-1	197
Microglia in Alzheimer's disease at single-cell level. Are there common patterns in humans and mice?	189
Neutrophil phenotypes and functions in cancer: A consensus statement	158
Dynamic innate immune response determines susceptibility to SARS-CoV-2 infection and early replication kinetics	152
Single-cell analysis of the cellular heterogeneity and interactions in the injured mouse spinal cord	150
CD36, a signaling receptor and fatty acid transporter that regulates immune cell metabolism and fate	149
Analysis of classical neutrophils and polymorphonuclear myeloid-derived suppressor cells in cancer patients and tumor-bearing mice	145
Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever live attenuated vaccine	144
Inflammation as a regulator of hematopoietic stem cell function in disease, aging, and clonal selection	140
Mapping and role of T cell response in SARS-CoV-2–infected mice	137
Tumor-infiltrating dendritic cell states are conserved across solid human cancers	137
Multi-omic profiling reveals widespread dysregulation of innate immunity and hematopoiesis in COVID-19	133
Glymphatic system clears extracellular tau and protects from tau aggregation and neurodegeneration	124
Activated microglia mitigate Aβ-associated tau seeding and spreading	116
Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions	114
B cells and cancer: To B or not to B?	112
Tissue-resident memory T cells in tumor immunity and immunotherapy	111
Innate immune pathways and inflammation in hematopoietic aging, clonal hematopoiesis, and MDS	109
Persistent cellular immunity to SARS-CoV-2 infection	107

STING agonist promotes CAR T cell trafficking and persistence in breast cancer	107
SARS-CoV-2–related MIS-C: A key to the viral and genetic causes of Kawasaki disease?	107
SARS-CoV-2 induces human plasmacytoid predendritic cell diversification via UNC93B and IRAK4	107
Tumor-derived IL-6 and trans-signaling among tumor, fat, and muscle mediate pancreatic cancer cachexia	106
The mRNA m6A reader YTHDF2 suppresses proinflammatory pathways and sustains hematopoietic stem cell function	103
The SIRPα–CD47 immune checkpoint in NK cells	101
Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis	98
The RNA m6A reader YTHDF2 controls NK cell antitumor and antiviral immunity	98
Optimized gene engineering of murine CAR-T cells reveals the beneficial effects of IL-15 coexpression	93
Single cell analysis of M. tuberculosis phenotype and macrophage lineages in the infected lung	93
Single-cell analysis of human skin identifies CD14+ type 3 dendritic cells co-producing IL1B and IL23A in psoriasis	89
Lung tumor MHCII immunity depends on in situ antigen presentation by fibroblasts	87
TREM2-dependent lipid droplet biogenesis in phagocytes is required for remyelination	85
SARS-CoV-2 breakthrough infection in vaccinees induces virus-specific nasal-resident CD8+ and CD4+ T cells of broad specificity	83
Alveolar macrophages rely on GM-CSF from alveolar epithelial type 2 cells before and after birth	83
TCR signal strength defines distinct mechanisms of T cell dysfunction and cancer evasion	83
Single-cell analyses identify circulating anti-tumor CD8 T cells and markers for their enrichment	81
Mitophagy-mediated adipose inflammation contributes to type 2 diabetes with hepatic insulin resistance	80
Autoantibody-mediated impairment of DNASE1L3 activity in sporadic systemic lupus erythematosus	78
Inhibition of macrophage histone demethylase JMJD3 protects against abdominal aortic aneurysms	77
Conserved meningeal lymphatic drainage circuits in mice and humans	75
A TRPA1 inhibitor suppresses neurogenic inflammation and airway contraction for asthma treatment	75
Early nasal type I IFN immunity against SARS-CoV-2 is compromised in patients with autoantibodies against type I IFNs	71
Germinal center–dependent and –independent memory B cells produced throughout the immune response	71
Lipid-loaded tumor-associated macrophages sustain tumor growth and invasiveness in prostate cancer	71
Endothelial LRP1 protects against neurodegeneration by blocking cyclophilin A	70
Recessive inborn errors of type I IFN immunity in children with COVID-19 pneumonia	70
Human autoantibodies underlying infectious diseases	70
Anti-tumor immunity in mismatch repair-deficient colorectal cancers requires type I IFN–driven CCL5 and CXCL10	68
Chronic TREM2 activation exacerbates Aβ-associated tau seeding and spreading	66
Intravenous administration of BCG protects mice against lethal SARS-CoV-2 challenge	66
In vivo labeling reveals continuous trafficking of TCF-1+ T cells between tumor and lymphoid tissue	65
TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C	64
Sphingosine 1-phosphate receptor 5 (S1PR5) regulates the peripheral retention of tissue-resident lymphocytes	64
Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions	63
LILRB4 suppresses immunity in solid tumors and is a potential target for immunotherapy	63
AIM2 controls microglial inflammation to prevent experimental autoimmune encephalomyelitis	62
Effects of dietary restriction on neuroinflammation in neurodegenerative diseases	62
Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia	62