OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Experimental Medicine is 55. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Early innate role for CD8αα+ cells in tuberculosis	236
S1PR1, an endothelial-immune influencer	162
ALK2/3 recruitment to the immunological synapse is required for T cell activation and death	147
Local gene editing of fibroblasts in tumors reveals a new cancer-associated fibroblast state	135
Primary tumor–derived systemic nANGPTL4 inhibits metastasis	129
Differential IL-12 signaling induces human natural killer cell activating receptor-mediated ligand-specific expansion	115
Epitope and HLA specificity of human TCRs against Plasmodium falciparum circumsporozoite protein	115
Intestinal epithelial c-Maf expression determines enterocyte differentiation and nutrient uptake in mice	110
The pathogenic role of retinoid nuclear receptor signaling in cancer and metabolic syndromes	110
Inhibition of astrocytic DRD2 suppresses CNS inflammation in an animal model of multiple sclerosis	109
SARS-CoV-2 Spike protein suppresses CTL-mediated killing by inhibiting immune synapse assembly	108
Antigen-independent, autonomous B cell receptor signaling drives activated B cell DLBCL	102
Host factor TIMP1 sustains long-lasting myeloid-biased hematopoiesis after severe infection	100
Antibody feedback contributes to facilitating the development of Omicron-reactive memory B cells in SARS-CoV-2 mRNA vaccinees	99
RORγt eTACs mediate oral tolerance and Treg induction	95
IL-21 shapes germinal center polarization via light zone B cell selection and cyclin D3 upregulation	95
B cell receptor ligation induces IgE plasma cell elimination	94
Prenatally derived macrophages support choroidal health and decline in age-related macular degeneration	92
High burden of viruses and bacterial pathobionts drives heightened nasal innate immunity in children	90
An iron-rich subset of macrophages promotes tumor growth through a Bach1-Ednrb axis	87
Common cold embecovirus imprinting primes broadly neutralizing antibody responses to SARS-CoV-2 S2	87
IFNγ score–based neoadjuvant immunotherapy for stage III melanoma	85
Obesity alters monocyte developmental trajectories to enhance metastasis	84
Heterozygous human JAK2V617F activates AhR to drive essential thrombocythemia and promote thrombosis	84
Lymphatic chain gradients regulate the magnitude and heterogeneity of T cell responses to vaccination	83

The genetic background shapes the susceptibility to mitochondrial dysfunction and NASH progression	83
A human STAT3 gain-of-function variant drives local Th17 dysregulation and skin inflammation in mice	82
Transit-amplifying cells control R-spondins in the mouse crypt to modulate intestinal stem cell proliferation	82
pDCs, type 1 IFN, and the female predileXion of SSc	79
T cell engagers emerge as a compelling therapeutic modality	77
Challenges in TB research	76
Non-professional efferocytosis of Salmonella-infected intestinal epithelial cells in the neonatal host	75
Loss of ATG7 in microglia impairs UPR, triggers ferroptosis, and weakens amyloid pathology control	74
NFAT5 governs cellular plasticity-driven resistance to KRAS-targeted therapy in pancreatic cancer	74
Dual role of vascular endothelial growth factor-C in post-stroke recovery	73
TIGIT mediates activation-induced cell death of ILC2s during chronic airway allergy	73
CD8+ T cell depletion prevents neuropathology in a mouse model of globoid cell leukodystrophy	70
Correction: ICAM-1 controls development and function of ILC2	70
CXCL12+ dermal fibroblasts promote neutrophil recruitment and host defense by recognition of IL-17	69
Correction: Segmented filamentous bacteria–induced epithelial MHCII regulates cognate CD4+ IELs and epithelial turnover	69
How decreasing T cell signaling unexpectedly results in autoimmunity	68
Nina Cabezas Wallscheid: Enjoying the freedom to decide my research path	67
Michelle Linterman: We are always learning	67
Spatiotemporal dynamics of fetal liver hematopoietic niches	65
MYC is a clinically significant driver of mTOR inhibitor resistance in breast cancer	64
Protein arginine methyltransferase 1 regulates B cell fate after positive selection in the germinal center in mice	64
Tingible body macrophages: Gargantuan chameleons of the germinal center	63
IEC-intrinsic IL-1R signaling holds dual roles in regulating intestinal homeostasis and inflammation	60
A twist in the tail: Of T cell subsets and disease	58
Memory B cell responses to Omicron subvariants after SARS-CoV-2 mRNA breakthrough infection in humans	58
Rethinking disomy: Autosomal expression bias	58
Somatic gain-of-function mutations in BUD13 promote oncogenesis by disrupting Fbw7 function	57
Oral antigen exposure under costimulation blockade induces Treg cells to establish immune tolerance	57
MYO1F in neutrophils is required for the response to immune checkpoint blockade therapy	56
Functional specialization of short-lived and long-lived macrophage subsets in human tonsils	55