OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Experimental Medicine is 57. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
S1PR1, an endothelial-immune influencer	307
ALK2/3 recruitment to the immunological synapse is required for T cell activation and death	252
Host factor TIMP1 sustains long-lasting myeloid-biased hematopoiesis after severe infection	196
Prenatally derived macrophages support choroidal health and decline in age-related macular degeneration	189
Antibody feedback contributes to facilitating the development of Omicron-reactive memory B cells in SARS-CoV-2 mRNA vaccinees	149
Intestinal epithelial c-Maf expression determines enterocyte differentiation and nutrient uptake in mice	133
The pathogenic role of retinoid nuclear receptor signaling in cancer and metabolic syndromes	132
Antigen-independent, autonomous B cell receptor signaling drives activated B cell DLBCL	123
RORγt eTACs mediate oral tolerance and Treg induction	116
Protection of ischemic white matter and oligodendrocytes in mice by 3K3A-activated protein C	108
Early innate role for CD8αα+ cells in tuberculosis	103
Differential IL-12 signaling induces human natural killer cell activating receptor-mediated ligand-specific expansion	101
Primary tumor–derived systemic nANGPTL4 inhibits metastasis	101
Neutralizing antibodies protect mice against Venezuelan equine encephalitis virus aerosol challenge	98
Epitope and HLA specificity of human TCRs against Plasmodium falciparum circumsporozoite protein	93
Inhibition of astrocytic DRD2 suppresses CNS inflammation in an animal model of multiple sclerosis	91
High burden of viruses and bacterial pathobionts drives heightened nasal innate immunity in children	89
SARS-CoV-2 Spike protein suppresses CTL-mediated killing by inhibiting immune synapse assembly	88
Common cold embecovirus imprinting primes broadly neutralizing antibody responses to SARS-CoV-2 S2	88
TCR signal strength defines distinct mechanisms of T cell dysfunction and cancer evasion	86
An iron-rich subset of macrophages promotes tumor growth through a Bach1-Ednrb axis	82
B cell receptor ligation induces IgE plasma cell elimination	81
IL-21 shapes germinal center polarization via light zone B cell selection and cyclin D3 upregulation	80
pDCs, type 1 IFN, and the female predileXion of SSc	79
IFNγ score–based neoadjuvant immunotherapy for stage III melanoma	78

Correction: ICAM-1 controls development and function of ILC2	77
Lymphatic chain gradients regulate the magnitude and heterogeneity of T cell responses to vaccination	77
Making memories with Bcl-6	76
CD8+ T cell depletion prevents neuropathology in a mouse model of globoid cell leukodystrophy	73
Transit-amplifying cells control R-spondins in the mouse crypt to modulate intestinal stem cell proliferation	71
Correction: Segmented filamentous bacteria–induced epithelial MHCII regulates cognate CD4+ IELs and epithelial turnover	71
A human STAT3 gain-of-function variant drives local Th17 dysregulation and skin inflammation in mice	70
Dual role of vascular endothelial growth factor-C in post-stroke recovery	68
CXCL12+ dermal fibroblasts promote neutrophil recruitment and host defense by recognition of IL-17	68
Heterozygous human JAK2V617F activates AhR to drive essential thrombocythemia and promote thrombosis	68
TIGIT mediates activation-induced cell death of ILC2s during chronic airway allergy	68
Non-professional efferocytosis of Salmonella-infected intestinal epithelial cells in the neonatal host	68
Loss of ATG7 in microglia impairs UPR, triggers ferroptosis, and weakens amyloid pathology control	68
The genetic background shapes the susceptibility to mitochondrial dysfunction and NASH progression	67
Challenges in TB research	67
NFAT5 governs cellular plasticity-driven resistance to KRAS-targeted therapy in pancreatic cancer	67
Systems-level conservation of the proximal TCR signaling network of mice and humans	66
A high OXPHOS CD8 T cell subset is predictive of immunotherapy resistance in melanoma patients	65
Hypoxia induces adrenomedullin from lung epithelia, stimulating ILC2 inflammation and immunity	64
Obesity alters monocyte developmental trajectories to enhance metastasis	63
Role of adipose tissue macrophages in obesity-related disorders	63
How decreasing T cell signaling unexpectedly results in autoimmunity	62
Somatic gain-of-function mutations in BUD13 promote oncogenesis by disrupting Fbw7 function	62
Michelle Linterman: We are always learning	61
MYO1F in neutrophils is required for the response to immune checkpoint blockade therapy	60
Nina Cabezas Wallscheid: Enjoying the freedom to decide my research path	60
Tingible body macrophages: Gargantuan chameleons of the germinal center	60
A twist in the tail: Of T cell subsets and disease	59
CD150-dependent hematopoietic stem cell sensing of Brucella instructs myeloid commitment	58
Targeting infection-specific peptides in immunopeptidomics studies for vaccine target discovery	58
Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses	58
Pleiotrophin drives a prometastatic immune niche in breast cancer	57
Immunomolecular and reactivity landscapes of gut IgA subclasses in homeostasis and inflammatory bowel disease	57
Protective fibroblastic niches in secondary lymphoid organs	57