OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Experimental Medicine is 58. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Antigen-independent, autonomous B cell receptor signaling drives activated B cell DLBCL	501
Host factor TIMP1 sustains long-lasting myeloid-biased hematopoiesis after severe infection	228
Early innate role for CD8αα+ cells in tuberculosis	223
Neutralizing antibodies protect mice against Venezuelan equine encephalitis virus aerosol challenge	202
The pathogenic role of retinoid nuclear receptor signaling in cancer and metabolic syndromes	192
Inhibition of astrocytic DRD2 suppresses CNS inflammation in an animal model of multiple sclerosis	183
Protection of ischemic white matter and oligodendrocytes in mice by 3K3A-activated protein C	175
Intestinal epithelial c-Maf expression determines enterocyte differentiation and nutrient uptake in mice	163
Bromodomain protein BRD4 directs and sustains CD8 T cell differentiation during infection	158
SARS-CoV-2 Spike protein suppresses CTL-mediated killing by inhibiting immune synapse assembly	156
Primary tumor–derived systemic nANGPTL4 inhibits metastasis	139
IL-21 shapes germinal center polarization via light zone B cell selection and cyclin D3 upregulation	134
Prenatally derived macrophages support choroidal health and decline in age-related macular degeneration	124
Human STAT3 variants underlie autosomal dominant hyper-IgE syndrome by negative dominance	119
ASC deglutathionylation is a checkpoint for NLRP3 inflammasome activation	118
B cell receptor ligation induces IgE plasma cell elimination	117
Sphingosine 1-phosphate receptor 5 (S1PR5) regulates the peripheral retention of tissue-resident lymphocytes	116
The microbial one-hit wonder	108
Antibody feedback contributes to facilitating the development of Omicron-reactive memory B cells in SARS-CoV-2 mRNA vaccinees	107
RORγt eTACs mediate oral tolerance and Treg induction	105
Stage-specific action of Runx1 and GATA3 controls silencing of PU.1 expression in mouse pro–T cells	101
Inflammation as a regulator of hematopoietic stem cell function in disease, aging, and clonal selection	98
High burden of viruses and bacterial pathobionts drives heightened nasal innate immunity in children	95
TCR signal strength defines distinct mechanisms of T cell dysfunction and cancer evasion	92
Differential IL-12 signaling induces human natural killer cell activating receptor-mediated ligand-specific expansion	89

An iron-rich subset of macrophages promotes tumor growth through a Bach1-Ednrb axis	85
Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions	81
Hypoxia induces adrenomedullin from lung epithelia, stimulating ILC2 inflammation and immunity	80
The genetic background shapes the susceptibility to mitochondrial dysfunction and NASH progression	80
Role of adipose tissue macrophages in obesity-related disorders	79
A high OXPHOS CD8 T cell subset is predictive of immunotherapy resistance in melanoma patients	77
Non-professional efferocytosis of Salmonella-infected intestinal epithelial cells in the neonatal host	75
Making memories with Bcl-6	75
IFNγ score–based neoadjuvant immunotherapy for stage III melanoma	74
pDCs, type 1 IFN, and the female predileXion of SSc	74
Dual role of vascular endothelial growth factor-C in post-stroke recovery	74
TIGIT mediates activation-induced cell death of ILC2s during chronic airway allergy	73
Challenges in TB research	73
Systems-level conservation of the proximal TCR signaling network of mice and humans	73
Correction: Segmented filamentous bacteria–induced epithelial MHCII regulates cognate CD4+ IELs and epithelial turnover	73
Obesity alters monocyte developmental trajectories to enhance metastasis	72
Implication of folate deficiency in CYP2U1 loss of function	70
Transit-amplifying cells control R-spondins in the mouse crypt to modulate intestinal stem cell proliferation	67
Posttranscriptional regulation of ILC2 homeostatic function via tristetraprolin	67
Single cell analysis of M. tuberculosis phenotype and macrophage lineages in the infected lung	66
A human STAT3 gain-of-function variant drives local Th17 dysregulation and skin inflammation in mice	64
Loss of ATG7 in microglia impairs UPR, triggers ferroptosis, and weakens amyloid pathology control	63
Lymphatic chain gradients regulate the magnitude and heterogeneity of T cell responses to vaccination	63
CD8+ T cell depletion prevents neuropathology in a mouse model of globoid cell leukodystrophy	63
CXCL12+ dermal fibroblasts promote neutrophil recruitment and host defense by recognition of IL-17	62
NFAT5 governs cellular plasticity-driven resistance to KRAS-targeted therapy in pancreatic cancer	60
IEC-intrinsic IL-1R signaling holds dual roles in regulating intestinal homeostasis and inflammation	60
CD150-dependent hematopoietic stem cell sensing of Brucella instructs myeloid commitment	59
Promiscuous recognition of MR1 drives self-reactive mucosal-associated invariant T cell responses	59
E3 ligase MKRN3 is a tumor suppressor regulating PABPC1 ubiquitination in non–small cell lung cancer	59
Immunomolecular and reactivity landscapes of gut IgA subclasses in homeostasis and inflammatory bowel disease	59
Extracellular vesicle– and particle-mediated communication shapes innate and adaptive immune responses	58
Spatiotemporal dynamics of fetal liver hematopoietic niches	58