Journal of Dental Research

Article	Citations
Oral Cancer Screening: Past, Present, and Future	183
Global Burden and Inequality of Dental Caries, 1990 to 2019	156
SARS-CoV-2 Detection in Gingival Crevicular Fluid	103
Host Modulation and Treatment of Periodontal Disease	93
Caries Detection on Intraoral Images Using Artificial Intelligence	91
Multiclass CBCT Image Segmentation for Orthodontics with Deep Learning	86
Teledentistry and mHealth for Promotion and Prevention of Oral Health: A Systematic Review and Meta-analysis	74
Cost-effectiveness of Artificial Intelligence for Proximal Caries Detection	70
Artificial Intelligence and Ethics in Dentistry: A Scoping Review	70
Biomineralization of Enamel and Dentin Mediated by Matrix Proteins	69
Areca Nut and Oral Cancer: Evidence from Studies Conducted in Humans	64
Sources of SARS-CoV-2 and Other Microorganisms in Dental Aerosols	61
The Importance of Nitrate Reduction for Oral Health	60
Frequent and Persistent Salivary Gland Ectasia and Oral Disease After COVID-19	58
Disease-Induced Changes in Salivary Gland Function and the Composition of Saliva	57
Periodontitis and Accelerated Biological Aging: A Geroscience Approach	54
Gut Microbiota May Mediate the Influence of Periodontitis on Prediabetes	53
COVID-19: Seroprevalence and Vaccine Responses in UK Dental Care Professionals	53
Mouthwashes with CPC Reduce the Infectivity of SARS-CoV-2 Variants In Vitro	53
Oral Manifestations in Patients with COVID-19: A 6-Month Update	52
Disruptive Innovation in Dentistry: What It Is and What Could Be Next	51
Progress in Dental Adhesive Materials	50
Dementia and the Risk of Periodontitis: A Population-Based Cohort Study	50
Electronic Cigarettes and Oral Health	43
Oral Microbiota Composition Predicts Early Childhood Caries Onset	42

RGS12 Represses Oral Cancer via the Phosphorylation and SUMOylation of PTEN	40
Mechanisms of Atomization from Rotary Dental Instruments and Its Mitigation	39
Pandemic Considerations on Essential Oral Health Care	39
Dental Pain and Worsened Socioeconomic Conditions Due to the COVID-19 Pandemic	39
Leptin Aggravates Periodontitis by Promoting M1 Polarization via NLRP3	37
Role of Dentistry in Global Health: Challenges and Research Priorities	37
Biomaterial and Biofilm Interactions with the Pulp-Dentin Complex-on-a-Chip	37
GSDME Is Related to Prognosis and Response to Chemotherapy in Oral Cancer	36
Ultrasonographic Tissue Perfusion in Peri-implant Health and Disease	36
Filifactor alocis: Recent Insights and Advances	35
SMDI: An Index for Measuring Subgingival Microbial Dysbiosis	35
Periodontitis and COVID-19: Biological Mechanisms and Meta-analyses of Epidemiological Evidence	35
Additive Effect of Periodontal Disease and Obesity on COVID-19 Outcomes	33
Consensus Statement on Future Directions for the Behavioral and Social Sciences in Oral Health	33
Hyperlipidemia Impairs Osseointegration via the ROS/Wnt/β-Catenin Pathway	33
Data Dentistry: How Data Are Changing Clinical Care and Research	32
Neuroinflammation: A Distal Consequence of Periodontitis	32
MMP-9 Levels and NaOCl Lavage in Randomized Trial on Direct Pulp Capping	31
CBD Promotes Oral Ulcer Healing via Inhibiting CMPK2-Mediated Inflammasome	31
The Human Salivary Proteome Wiki: A Community-Driven Research Platform	31
Periodontitis Salivary Microbiota Worsens Colitis	30
Systematic Review of the Effect on Caries of Sugars Intake: Ten-Year Update	30
Role of Primary Cilia in Bone and Cartilage	29
The Role of Gingival Fibroblasts in the Pathogenesis of Periodontitis	29
Alveolar Bone Marrow Gli1+ Stem Cells Support Implant Osseointegration	29
Metabolomics Insights in Early Childhood Caries	29
Oral Organoids: Progress and Challenges	29
BMSC-Derived ApoEVs Promote Craniofacial Bone Repair via ROS/JNK Signaling	29
Regulating Fibrocartilage Stem Cells via TNF-α/Nf-κB in TMJ Osteoarthritis	28
Cetylpyridinium Chloride Mouthwash to Reduce Shedding of Infectious SARS-CoV-2: A Double-Blind Randomized Clinical Trial	28
Immune Changes Induced by Orthodontic Forces: A Critical Review	28
Toward Clinically Applicable 3-Dimensional Tooth Segmentation via Deep Learning	27
RGS12 Drives Macrophage Activation and Osteoclastogenesis in Periodontitis	26
Towards Trustworthy AI in Dentistry	25
The Contribution of Macrophages in Old Mice to Periodontal Disease	25
A Biphasic Feature of Gli1+-Mesenchymal Progenitors during Cementogenesis That Is Positively Controlled by Wnt/β-Catenin Signaling	25
METTL3-Dependent Glycolysis Regulates Dental Pulp Stem Cell Differentiation	24
Oral Status and Dementia Onset: Mediation of Nutritional and Social Factors	24
Dental Mitigation Strategies to Reduce Aerosolization of SARS-CoV-2	24
Automatic 3-Dimensional Cephalometric Landmarking via Deep Learning	24
Dental Emergencies Management in COVID-19 Pandemic Peak: A Cohort Study	24
Histopathology-Based Diagnosis of Oral Squamous Cell Carcinoma Using Deep Learning	24
Lrp6 Dynamic Expression in Tooth Development and Mutations in Oligodontia	23
A Critical Review of Dental Lithia-Based Glass–Ceramics	23
Role of Taste Receptors in Innate Immunity and Oral Health	23
Federated Learning in Dentistry: Chances and Challenges	23
Reorienting Oral Health Services to Prevention: Economic Perspectives	23
RUNX2 Regulates Osteoblast Differentiation via the BMP4 Signaling Pathway	23
Ventilation Assessment by Carbon Dioxide Levels in Dental Treatment Rooms	22
Pathways Linking Oral Bacteria, Nitric Oxide Metabolism, and Health	22

Dentin Cross-linking Effect of Carbodiimide After 5 Years	22
Oral Candida Predicts Streptococcus mutans Emergence in Underserved US Infants	22
Identification of Type H Vessels in Mice Mandibular Condyle	22
Nano-Layering Adds Strength to the Adhesive Interface	22
SARS-CoV-2 Positivity in Asymptomatic-Screened Dental Patients	21
Severe Periodontal Disease Increases Acute Myocardial Infarction and Stroke: A 10-Year Retrospective Follow-up Study	21
MiR-302b Suppresses Tumor Metastasis by Targeting Frizzled 6 in OSCC	21
Trem1 Induces Periodontal Inflammation via Regulating M1 Polarization	21
Touch-Cure Polymerization at the Composite Cement-Dentin Interface	21
Axin2+ PDL Cells Directly Contribute to New Alveolar Bone Formation in Response to Orthodontic Tension Force	20
Factors Associated with Extraction following Root Canal Filling in Adults	20
Artificial Intelligence for Caries Detection: Value of Data and Information	20
Automated Radiographic Evaluation of Adenoid Hypertrophy Based on VGG-Lite	20
EpsR Negatively Regulates Streptococcus mutans Exopolysaccharide Synthesis	20
Mechanisms of Enamel Mineralization Guided by Amelogenin Nanoribbons	19
Trajectories of Sugar Consumption and Dental Caries in Early Childhood	19
DPSC-Derived Extracellular Vesicles Promote Rat Jawbone Regeneration	19
Advances in Head and Neck Cancer Pain	19
Safety and In Situ Antierosive Effect of CaneCPI-5 on Dental Enamel	19
Impact of Reducing Water Fluoride on Dental Caries and Fluorosis	19
γδT Cells Are Essential for Orthodontic Tooth Movement	19
High-Resolution Detection of Translocation of Oral Bacteria to the Gut	19
Calcium Signaling in T Cells and Chronic Inflammatory Disorders of the Oral Cavity	18
Better Reporting of Studies on Artificial Intelligence: CONSORT-AI and Beyond	18
The Application of Organs-on-a-Chip in Dental, Oral, and Craniofacial Research	18
Biomineralization of Dental Tissues Treated with Silver Diamine Fluoride	18
The Type IX Secretion System and Its Role in Bacterial Function and Pathogenesis	18
Fabrication of Vascularized DPSC Constructs for Efficient Pulp Regeneration	18
Oral Microbiota Transplant in Dogs with Naturally Occurring Periodontitis	18
Role of Mechanotransduction in Periodontal Homeostasis and Disease	17
From Bite to Byte: Dental Structures Resolved at a Single-Cell Resolution	17
HIF-1α Stabilization Boosts Pulp Regeneration by Modulating Cell Metabolism	17
ORAOV1-B Promotes OSCC Metastasis via the NF-κB-TNFα Loop	17
Graphene Nanocoating: High Quality and Stability upon Several Stressors	17
Ckip-1 Mediates P. gingivalis–Suppressed Cementoblast Mineralization	17
Dental Care Use, Edentulism, and Systemic Health among Older Adults	17
Activation of Functional Somatic Stem Cells Promotes Endogenous Tissue Regeneration	17
Single-Cell Transcriptomic Atlas of Gingival Mucosa in Type 2 Diabetes	17
Impact of Teeth on Social Participation: Modified Treatment Policy Approach	17
3D-Printed Polycaprolactone Reinforced Hydrogel as an Artificial TMJ Disc	17
Bifunctional Composites for Biofilms Modulation on Cervical Restorations	17
HCV Infection Alters Salivary Gland Histology and Saliva Composition	16
A Review of Mechano-Biochemical Models for Testing Composite Restorations	16
Deep Learning–Based Prediction of the 3D Postorthodontic Facial Changes	16
Systemic Multimorbidity Clusters in People with Periodontitis	16
Treponema denticola Induces Alzheimer-Like Tau Hyperphosphorylation by Activating Hippocampal Neuroinflammation in Mice	16
FOXO3 Mediates Tooth Movement by Regulating Force-Induced Osteogenesis	16
UCHL1 Impairs Periodontal Ligament Stem Cell Osteogenesis in Periodontitis	16
Benchmarking Deep Learning Models for Tooth Structure Segmentation	16
Acute Postoperative Pain Due to Dental Extraction in the Adult Population: A Systematic Review and Network Meta-analysis	16
Gli1+-PDL Cells Contribute to Alveolar Bone Homeostasis and Regeneration	16
Chitosan-Calcium-Simvastatin Scaffold as an Inductive Cell-Free Platform	16
Local Exhaust Ventilation to Control Dental Aerosols and Droplets	16
GSK3 Inhibitor-Induced Dentinogenesis Using a Hydrogel	16
Melatonin Abates TMJOA Chronic Pain by MT2R in Trigeminal Ganglion Neurons	16
Novel Preosteoclast Populations in Obesity-Associated Periodontal Disease	16
A Novel Competence Pathway in the Oral Pathogen Streptococcus sobrinus	15
γδ T Cells Differentially Regulate Bone Loss in Periodontitis Models	15
Host Genetic Associations with Salivary Microbiome in Oral Cancer	15
Key Elements of Gingival Epithelial Homeostasis upon Bacterial Interaction	15
Excess Risk of Dental Caries from Higher Free Sugars Intake Combined with Low Exposure to Water Fluoridation	15
Medicine and Dentistry Working Side by Side to Improve Global Health Equity	15
Social Mobility and Tooth Loss: A Systematic Review and Meta-analysis	14
CGRP and Shh Mediate the Dental Pulp Cell Response to Neuron Stimulation	14
ALPK1 Aggravates TMJOA Cartilage Degradation via NF-κB and ERK1/2 Signaling	14
Mental Disorders and Oral Diseases: Future Research Directions	14
WWP2 Promotes Odontoblastic Differentiation by Monoubiquitinating KLF5	14
Effectiveness and Policy Determinants of Sugar-Sweetened Beverage Taxes	14
Weight Loss Mediated the Relationship between Tooth Loss and Mortality Risk	14
Identification of Dental Implant Systems Using a Large-Scale Multicenter Data Set	14
In Situ Oxygen Generation Enhances the SCAP Survival in Hydrogel Constructs	14
Multicompartmental Scaffolds for Coordinated Periodontal Tissue Engineering	14
Med23 Regulates Sox9 Expression during Craniofacial Development	14
Inhibiting Hh Signaling in Gli1+ Osteogenic Progenitors Alleviates TMJOA	14
The Bone Sialoprotein RGD Domain Modulates and Maintains Periodontal Development	13
Zeb1 Promotes Odontoblast Differentiation in a Stage-Dependent Manner	13
Effects of Active Vitamin D or FGF23 Antibody on Hyp Mice Dentoalveolar Tissues	13
Interpretable AI Explores Effective Components of CAD/CAM Resin Composites	13
Human Bone Marrow Stromal Cell Exosomes Ameliorate Periodontitis	13
Retinoic Acid Deficiency Underlies the Etiology of Midfacial Defects	13

MSX1 Drives Tooth Morphogenesis Through Controlling Wnt Signaling Activity	13
Applications of Cryogenic Electron Microscopy in Biomineralization Research	13
The Prevalence of Gingival Dendritic Cell Subsets in Periodontal Patients	13
MDP Salts: A New Bonding Strategy for Zirconia	13
Entamoeba gingivalis Exerts Severe Pathogenic Effects on the Oral Mucosa	13
Developing Bioactive Dental Resins for Restorative Dentistry	13
Impact of Powered Toothbrush Use and Interdental Cleaning on Oral Health	12
Matrix Vesicle–Mediated Mineralization and Potential Applications	12
Integration of Single-Cell RNA- and CAGE-seq Reveals Tooth-Enriched Genes	12
Periodontitis and Dementia: A Bidirectional Relationship?	12
Role of Discoidin Domain Receptor 2 in Craniofacial Bone Regeneration	12
Wnt1 Promotes Cementum and Alveolar Bone Growth in a Time-Dependent Manner	12
LncRNA Nron Inhibits Bone Resorption in Periodontitis	12
A Roadmap for the Human Oral and Craniofacial Cell Atlas	12
Recessive Mutations in ACP4 Cause Amelogenesis Imperfecta	12
Development of Rat Caries-Induced Pulpitis Model for Vital Pulp Therapy	12
Transcriptomic Mapping of Human Parotid Gland at Single-Cell Resolution	12
Tertiary Lymphoid Structure Raises Survival and Immunotherapy in HPV− HNSCC	12
Ablation of Pyrophosphate Regulators Promotes Periodontal Regeneration	12
TiO2 Nanonetwork on Rough Ti Enhanced Osteogenesis In Vitro and In Vivo	12
Antiresorptive-Type and Discontinuation-Timing Affect ONJ Burden	12
Periodontal Pathogens Promote Foam Cell Formation by Blocking Lipid Efflux	12
Dental Research Data Availability and Quality According to the FAIR Principles	12
Impact of Treatment on Host Responses in Young Individuals with Periodontitis	12
Distinct Microbial Signatures between Periodontal Profile Classes	12
Enamel Caries Detection and Diagnosis: An Analysis of Systematic Reviews	12
Inductive Materials for Regenerative Engineering	12
Cell Type–Specific Decomposition of Gingival Tissue Transcriptomes	12
Treponema denticola Promotes OSCC Development via the TGF-β Signaling Pathway	12
Immigration and Oral Health in Older Adults: An Integrative Approach	12
Gas1 Regulates Patterning of the Murine and Human Dentitions through Sonic Hedgehog	11
Microrobotics for Precision Biofilm Diagnostics and Treatment	11
Endothelial Insulin Resistance Exacerbates Experimental Periodontitis	11
Degradable RGD-Functionalized 3D-Printed Scaffold Promotes Osteogenesis	11
Fibromodulin, a Multifunctional Matricellular Modulator	11
Big Data and Complex Data Analytics: Breaking Peer Review?	11
Effects of CGRP-Primed Dental Pulp Stem Cells on Trigeminal Sensory Neurons	11
Co-occurrence of Periodontitis and Diabetes-Related Complications	11
Does Periodontitis Affect the Association of Biological Aging with Mortality?	11
NLRP3 Disturbs Treg/Th17 Cell Balance to Aggravate Apical Periodontitis	11
Bisphenol A Exposure Disrupts Enamel Formation via EZH2-Mediated H3K27me3	11
Printable PICN Composite Mechanically Compatible with Human Teeth	11
Efficacy of a Mouthwash Containing CHX and CPC in SARS-CoV-2–Positive Patients: A Randomized Controlled Clinical Trial	11
Some Myths in Dentin Bonding: An Evidence-Based Perspective	11
Cigarette Smoke Exposure Inhibits Osteoclast Apoptosis via the mtROS Pathway	11
A Pair of “ACEs”	11
A Shifting Paradigm: Transformation of Cartilage to Bone during Bone Repair	11
Retroductal Delivery of Epidermal Growth Factor Protects Salivary Progenitors after Irradiation	11
Identification of Periosteal Osteogenic Progenitors in Jawbone	11
Transcriptional Regulation of Jaw Osteoblasts: Development to Pathology	10
Antibacterial and Osteoinductive Implant Surface Using Layer-by-Layer Assembly	10
Oral Health Equity Must Address Oppression: On the BSSOH Consensus Statement	10
Orthodontic Force–Induced BMAL1 in PDLCs Is a Vital Osteoclastic Activator	10
Oxidative Stress Inhibits Endotoxin Tolerance and May Affect Periodontitis	10
Oral Health in the Population Assessment of Tobacco and Health Study	10
Root Canal Treatment Survival Analysis in National Dental PBRN Practices	10
Mechanisms and Therapeutic Modulation of Neutrophil-Mediated Inflammation	10
Dental Services and Health Outcomes in the New York State Medicaid Program	10
Mucoadhesive Nucleoside-Based Hydrogel Delays Oral Leukoplakia Canceration	10
TLR9 Mediates Periodontal Aging by Fostering Senescence and Inflammaging	10
CXCL12/CXCR4 Mediates Orthodontic Root Resorption via Regulating the M1/M2 Ratio	10
Loss of IκBζ Drives Dentin Formation via Altered H3K4me3 Status	10
Methodological Gaps in Studying the Oral-Systemic Disease Connection	10
Dissecting the Role of VicK Phosphatase in Aggregation and Biofilm Formation of Streptococcus mutans	10
Mental Health and Oral Health in a Nationally Representative Cohort	10
Bone Sialoprotein Is Critical for Alveolar Bone Healing in Mice	10
Nicotinamide Improves Delayed Tooth Eruption in Runx2+/− Mice	10
Loss of RAP2A Aggravates Cartilage Degradation in TMJOA via YAP Signaling	9
FoxO1 as a Regulator of Aquaporin 5 Expression in the Salivary Gland	9
New Ameloblastoma Cell Lines Enable Preclinical Study of Targeted Therapies	9
Saliva and Serum Protein Adsorption on Chemically Modified Silica Surfaces	9
The Emerging Role of Accelerated Cellular Senescence in Periodontitis	9
Aberrant Brain Signal Variability and COMT Genotype in Chronic TMD Patients	9
Novel REST Truncation Mutations Causing Hereditary Gingival Fibromatosis	9
Chronological and Replicative Aging of CD51+/PDGFR-α+ Pulp Stromal Cells	9
Bioinspired Anti-demineralization Enamel Coating for Orthodontics	9
Causal Inference: Onward and Upward!	9
Association of Education and Depressive Symptoms with Tooth Loss	9
HBP/O-GlcNAcylation Metabolic Axis Regulates Bone Resorption Outcome	9
A Systematic Review and Meta-analysis of the Effect of Oral Exercises on Masticatory Function	9
Successful Application of a Galanin-Coated Scaffold for Periodontal Regeneration	9
Interface between Materials and Oral Biology	9
Harnessing Dental Stem Cell Immunoregulation Using Cell-Laden Biomaterials	9
Genome-wide Gene-by-Sex Interaction Studies Identify Novel Nonsyndromic Orofacial Clefts Risk Locus	9
Front-of-Package Food Labeling to Reduce Caries: Economic Evaluation	9
Dual Functions of MDP Monomer with De- and Remineralizing Ability	9
Ethnic Disparities in Dental Caries among Adolescents in China	9
Oral Pathobionts Promote MS-like Symptoms in Mice	8
Occlusal Force Maintains Alveolar Bone Homeostasis via Type H Angiogenesis	8
Translating Dental, Oral, and Craniofacial Regenerative Medicine Innovations to the Clinic through Interdisciplinary Commercial Translation Architecture	8
Delivery of Alkaline Phosphatase Promotes Periodontal Regeneration in Mice	8
Effects of Octenidine on the Formation and Disruption of Dental Biofilms: An Exploratory In Situ Study in Healthy Subjects	8
Cyclic di-AMP Rescues Porphyromonas gingivalis–Aggravated Atherosclerosis	8
Pcsk9 Knockout Aggravated Experimental Apical Periodontitis via LDLR	8
Dlx3 Ubiquitination by Nuclear Mdm2 Is Essential for Dentinogenesis in Mice	8