Journal of Clinical Pathology

Article	Citations
Histopathological observations in COVID-19: a systematic review	123
Gene of the month: the 2019-nCoV/SARS-CoV-2 novel coronavirus spike protein	117
Rosai-Dorfman disease: an overview	110
Cancer diagnostic rates during the 2020 ‘lockdown’, due to COVID-19 pandemic, compared with the 2018–2019: an audit study from cellular pathology	95
Protein tyrosine phosphatase receptor type C (PTPRC or CD45)	89
Towards effective diagnostic assays for COVID-19: a review	80
Gene of the month: TMPRSS2 (transmembrane serine protease 2)	72
COVID-19 autopsy in people who died in community settings: the first series	59
COVID-19 salivary signature: diagnostic and research opportunities	58
Current and future applications of artificial intelligence in pathology: a clinical perspective	55
PD-L1 expression by Tumor Proportion Score (TPS) and Combined Positive Score (CPS) are similar in non-small cell lung cancer (NSCLC)	53
Fatal pulmonary fibrosis: a post-COVID-19 autopsy case	47
Diagnostic concordance and discordance in digital pathology: a systematic review and meta-analysis	46
Digital pathology and artificial intelligence will be key to supporting clinical and academic cellular pathology through COVID-19 and future crises: the PathLAKE consortium perspective	43
Cytology in the time of coronavirus disease (COVID-19): an Italian perspective	36
Gene of the month: lymphocyte-activation gene 3 (LAG-3)	35
DNA mismatch repair proteins: scientific update and practical guide	35
Analysis of real-world PD-L1 IHC 28-8 and 22C3 pharmDx assay utilisation, turnaround times and analytical concordance across multiple tumour types	35
SMARCA family of genes	34
Role of digital pathology in diagnostic histopathology in the response to COVID-19: results from a survey of experience in a UK tertiary referral hospital	33
SARS-CoV-2 detection in formalin-fixed paraffin-embedded tissue specimens from surgical resection of tongue squamous cell carcinoma	31
Accuracy and stability of saliva as a sample for reverse transcription PCR detection of SARS-CoV-2	30
Platelet aggregates, a marker of severe COVID-19 disease	29
Implementing a structured digital-based online pathology curriculum for trainees at the time of COVID-19	29
HPV-related squamous cell carcinoma of oropharynx: a review	29

Placental microbial–metabolite profiles and inflammatory mechanisms associated with preterm birth	27
Histopathological features of multiorgan percutaneous tissue core biopsy in patients with COVID-19	26
Detection of microsatellite instability in a panel of solid tumours with the Idylla MSI Test using extracted DNA	25
Cross-reactivity of SARS-CoV-2 with HIV chemiluminescent assay leading to false-positive results	25
Gene of the month: DICER1: ruler and controller	25
Injuries and deaths from lightning	23
Use of whole slide imaging (WSI) for distance teaching	23
Molecules in pathogenesis: angiotensin converting enzyme 2 (ACE2)	22
Digital pathology and COVID-19 and future crises: pathologists can safely diagnose cases from home using a consumer monitor and a mini PC	21
Epigenetic-sensitive liquid biomarkers and personalised therapy in advanced heart failure: a focus on cell-free DNA and microRNAs	21
Low-grade oncocytic tumour expands the spectrum of renal oncocytic tumours and deserves separate classification: a review of 23 cases from a single tertiary institute	21
Molecular diagnosis in non-small-cell lung cancer: expert opinion on ALK and ROS1 testing	21
Digital pathology in the time of corona	21
High burden of acute kidney injury in COVID-19 pandemic: systematic review and meta-analysis	21
Carbonic anhydrase IX: a regulator of pH and participant in carcinogenesis	20
Rocky road to digital diagnostics: implementation issues and exhilarating experiences	19
Reduced sensitivity for EGFR T790M mutations using the Idylla EGFR Mutation Test	18
Future of biomarker evaluation in the realm of artificial intelligence algorithms: application in improved therapeutic stratification of patients with breast and prostate cancer	18
Tumour immune microenvironment biomarkers predicting cytotoxic chemotherapy efficacy in colorectal cancer	18
Assessment of mitotic activity in breast cancer: revisited in the digital pathology era	18
Fibroblast growth factor receptor (FGFR) gene: pathogenesis and treatment implications in urothelial carcinoma of the bladder	18
Clinical implementation of circulating tumour DNA testing for EGFR T790M for detection of treatment resistance in non-small cell lung cancer	17
Preanalytical issues affecting the diagnosis of COVID-19	17
Thyroid autoantibodies	17
Haemophagocytic lymphohistiocytosis after ChAdOx1 nCoV-19 vaccination	16
Variability in haemoglobin concentration by measurement tool and blood source: an analysis from seven countries	16
Identification of potential crucial genes associated with the pathogenesis and prognosis of liver hepatocellular carcinoma	15
Homocystinuria diagnosis and management: it is not all classical	15
IHC versus FISH versus NGS to detect ALK gene rearrangement in NSCLC: all questions answered?	15
Assessment of the effect of the COVID-19 pandemic on UK HbA1c testing: implications for diabetes management and diagnosis	15
Secondary haemophagocytic lymphohistiocytosis in COVID-19: correlation of the autopsy findings of bone marrow haemophagocytosis with HScore	15
Idylla microsatellite instability assay versus mismatch repair immunohistochemistry: a retrospective comparison in gastric adenocarcinoma	14
Mutations in ZP4 are associated with abnormal zona pellucida and female infertility	14
Real-world programmed death-ligand 1 prevalence rates in non-small cell lung cancer: correlation with clinicopathological features and tumour mutation status	14
Hypophosphatasia	14
Diagnostic approach in TFE3-rearranged renal cell carcinoma: a multi-institutional international survey	14
Xp11 translocation renal cell carcinoma with morphological features mimicking multilocular cystic renal neoplasm of low malignant potential: a series of six cases with molecular analysis	14
Establishment of a remote diagnostic histopathology service using whole slide imaging (digital pathology)	14
UK recommendations for HER2 assessment in breast cancer: an update	13
Is FURIN gene expression in salivary glands related to SARS-CoV-2 infectivity through saliva?	13
Genetic variations in the human severe acute respiratory syndrome coronavirus receptor ACE2 and serine protease TMPRSS2	13
Service evaluation of faecal immunochemical testing introduced for use in North East London for patients at low risk of colorectal cancer	12
Gene of the month: FH	12
Clinicopathological significance of CD47 expression in hepatocellular carcinoma	12
Specific cell differentiation in breast cancer: a basis for histological classification	12
Adrenal insufficiency	12
Diagnostic performance of melanocytic markers for immunocytochemical evaluation of lymph-node melanoma metastases on cytological samples	11
Predictive molecular pathology in the time of coronavirus disease (COVID-19) in Europe	11
Gene of the month: GTF2I	11
Industry payments to pathologists in the USA between 2013 and 2021	11

Gene of the month: TFE 3	11
Clinicopathological and molecular features of hereditary leiomyomatosis and renal cell cancer-associated renal cell carcinomas	11
Significance of PI3K signalling pathway in clear cell renal cell carcinoma in relation to VHL and HIF status	11
Extended storage of SARS-CoV-2 nasopharyngeal swabs does not negatively impact results of molecular-based testing across three clinical platforms	11
Best practice for LDL-cholesterol: when and how to calculate	11
Update on the current opinion, status and future development of digital pathology in Switzerland in light of COVID-19	11
Laboratory parameters in patients with COVID-19 on first emergency admission is different in non-survivors: albumin and lactate dehydrogenase as risk factors	11
Viropathic multinuclear syncytial giant cells in bronchial fluid from a patient with COVID-19	11
Pathologists can get it right the first time	10
Next-generation sequencing and histological response assessment in peritoneal metastasis from pancreatic cancer treated with PIPAC	10
Implementing NGS-basedBRCAtumour tissue testing in FFPE ovarian carcinoma specimens: hints from a real-life experience within the framework of expert recommendations	10
Abnormal umbilical cord insertions in singleton deliveries: placental histology and neonatal outcomes	10
Haemorrhagic enteritis and COVID-19: causality or coincidence	10
Brain autopsies in fatal COVID-19 and postulated pathophysiology: more puzzling than a Rubik’s cube	10
Performance evaluation of the Biocartis Idylla EGFR Mutation Test using pre-extracted DNA from a cohort of highly characterised mutation positive samples	10
Kinetics of SARS-CoV-2 antibody responses pre-COVID-19 and post-COVID-19 convalescent plasma transfusion in patients with severe respiratory failure: an observational case–control study	10
Detection of COX-2 in liquid biopsy in patients with breast cancer	10
Prevalence of mismatch repair deficiency and Lynch syndrome in a cohort of unselected small bowel adenocarcinomas	10
Real-world digital pathology: considerations and ruminations of four young pathologists	10
Real-world biomarker testing rate and positivity rate in NSCLC in Spain: Prospective Central Lung Cancer Biomarker Testing Registry (LungPath) from the Spanish Society of Pathology (SEAP)	10
Mid-regional proadrenomedullin (MR-proADM), C-reactive protein (CRP) and other biomarkers in the early identification of disease progression in patients with COVID-19 in the acute NHS setting	10
Adequacy of small biopsy and cytology specimens for comprehensive genomic profiling of patients with non-small-cell lung cancer to determine eligibility for immune checkpoint inhibitor and targeted th	10
Mutational profiling in suspected triple-negative essential thrombocythaemia using targeted next-generation sequencing in a real-world cohort	10
Evaluation of an open-source machine-learning tool to quantify bone marrow plasma cells	9
Atypical lymphoid cells circulating in blood in COVID-19 infection: morphology, immunophenotype and prognosis value	9
Gene of the month: GLIS1-3	9
Correlation between circulating blood and microenvironment T lymphocytes in diffuse large B-cell lymphomas	9
Hypertriglyceridaemia: an update	9
Molecular characterisation of pancreatic ductal adenocarcinoma withNTRKfusions and review of the literature	9
Gene of the month: T-cell immunoreceptor with immunoglobulin and ITIM domains (TIGIT)	9
Integration of rapid PCR testing as an adjunct to NGS in diagnostic pathology services within the UK: evidence from a case series of non-squamous, non-small cell lung cancer (NSCLC) patients with foll	9
Short history of 5-methylcytosine: from discovery to clinical applications	9
Cytokeratin 18 cell death assays as biomarkers for quantification of apoptosis and necrosis in COVID-19: a prospective, observational study	9
Clinicopathological characteristics and genetic variations of uterine tumours resembling ovarian sex cord tumours	9
Gene of the month: H3F3A and H3F3B	9
Predictive molecular pathology in the time of COVID-19	9
Reference standards for gene fusion molecular assays on cytological samples: an international validation study	9
Performance of gastrointestinal pathologists within a national digital review panel for Barrett’s oesophagus in the Netherlands: results of 80 prospective biopsy reviews	9
Evaluation of KRAS, NRAS and BRAF mutational status and microsatellite instability in early colorectal carcinomas invading the submucosa (pT1): towards an in-house molecula	9
Pathology training in the age of artificial intelligence	8
Correlation of BRAF mutational status with clinical characteristics and survival outcomes of patients with ameloblastoma: the experience of 11 Italian centres	8
Variation in breast cancer grading: the effect of creating awareness through laboratory-specific and pathologist-specific feedback reports in 16 734 patients with breast cancer	8
Significance of adenosquamous proliferation in breast lesions	8
Unique correlation between GTF2I mutation and spindle cell morphology in thymomas (type A and AB thymomas)	8
Molecular classification of endometrial carcinoma: a clinically oriented review	8
Antibody response and self-reported adverse reactions following vaccination with Comirnaty: a pilot study from a Croatian university hospital	8
Positivity for SATB2 distinguishes Islet1 positive rectal neuroendocrine tumours from pancreaticoduodenal neuroendocrine tumours	8
Three-antibody classifier for muscle invasive urothelial carcinoma and its correlation with p53 expression	8
CXCR4/ACKR3/CXCL12 axis in the lymphatic metastasis of vulvar squamous cell carcinoma	8
High methionyl–tRNA synthetase expression predicts poor prognosis in patients with breast cancer	8
Performance of the CellaVision DC-1 digital cell imaging analyser for differential counting and morphological classification of blood cells	8
Quantitative morphometrics reveals glomerular changes in patients with infrequent segmentally sclerosed glomeruli	8
Mutation spectrum and erythrocyte indices characterisation of α-thalassaemia and β-thalassaemia in Sichuan women in China: a thalassaemia screening survey of 42 155 women	8
Pathologists and the coronavirus distraction effect	8
Fibronodular hepatocellular carcinoma—a new variant of liver cancer: clinical, pathological and radiological correlation	8
Gene of the month: IDH1	8
Cellular pathology in the COVID-19 era: a European perspective on maintaining quality and safety	8
Filling the gap between histology and cytology: description of an innovative technology (Cytomatrix) to increase the diagnostic effectiveness of fine needle aspirates data	8
Impact of COVID-19 on small biopsy diagnostic procedures and cancer resection surgeries in the North-West of Ireland	7
MDM2 gene amplification as selection tool for innovative targeted approaches in PD-L1 positive or negative muscle-invasive urothelial bladder carcinoma	7
Compound computer vision workflow for efficient and automated immunohistochemical analysis of whole slide images	7
Cryptosporidiumspp surveillance and epidemiology in Ireland: a longitudinal cohort study employing duplex real-time PCR based speciation of clinical cases	7
Comparative clinicopathological and immunohistochemical study of micronodular thymoma and micronodular thymic carcinoma with lymphoid stroma	7
Clinicopathological predictors of survival in resected primary lung adenocarcinoma	7
Fostering intrinsic motivation in remote undergraduate histopathology education	7
Gene of the month: NKX3.1	7
Biochemical assessment of adequate levothyroxine replacement in primary hypothyroidism differs with different TSH assays: potential clinical implications	7
Immunoinformatic approach to assess SARS-CoV-2 protein S epitopes recognised by the most frequent MHC-I alleles in the Brazilian population	7
Methylation study of the Paris system for reporting urinary (TPS) categories	7
Construction of a reference material panel for detecting KRAS/NRAS/EGFR/BRAF/MET mutations in plasma ctDNA	7
Non-neoplastic colorectal disease biopsies: evaluation and differential diagnosis	7
Soluble type immune checkpoint regulators using multiplex luminex immunoassay in chronic hepatitis B patients	7
Morphological control for molecular testing: a practical approach	7
Cost analysis of archives in the pathology laboratories: from safety to management	7
Pathology of IgG4-related sclerosing mastitis	7
Public perceptions on pathology: a fundamental change is required	6
Gene of the month: TLE 1	6
Expression and correlation analysis of Skp2 and CBX7 in cervical cancer	6
Immune gene expression profiles in high-grade urothelial carcinoma of the bladder: a NanoString study	6
Prognostic values of L-type amino acid transporter 1 and CD98hc expression in breast cancer	6

Microsatellite instability evaluation: which test to use for endometrial cancer?	6
Improved pathology reporting in NAFLD/NASH for clinical trials	6
Five simple reasons to discard DIP, or why we should stop calling dolphins big fish	6
Liquid biopsy for BRAF mutations testing in non-small cell lung cancer: a retrospective study	6
Ethnicity influences total serum vitamin B12 concentration: a study of Black, Asian and White patients in a primary care setting	6
Gene of the month: STK11	6
Difficulties in diagnostics of lung tumours in biopsies: an interpathologist concordance study evaluating the international diagnostic guidelines	6
Advanced pathological study for definite diagnosis of mitochondrial cardiomyopathy	6
Cancer-associated fibroblasts (CAFs) in thyroid papillary carcinoma: molecular networks and interactions	6
Expression of cathepsins B, D and K in thymic epithelial tumours	6
Frequency of microsatellite instability (MSI) in upper tract urothelial carcinoma: comparison of the Bethesda panel and the Idylla MSI assay in a consecutively collected, multi-institutional cohort	6
Clinical and laboratory characteristics in outpatient diagnosis of COVID-19 in healthcare professionals in Rio de Janeiro, Brazil	6
PTEN as a target in melanoma	6
High case fatality rate in individuals with Down syndrome and COVID-19 in Brazil: a two-year report	6
Expression and clinical significance of a new neuroendocrine marker secretagogin in cervical neuroendocrine carcinoma	6
Expression of the immunoproteasome subunit β5i in non-small cell lung carcinomas	6
Faster than light (microscopy): superiority of digital pathology over microscopy for assessment of immunohistochemistry	6
Expression of YAP1 and pSTAT3-S727 and their prognostic value in glioma	6
Evaluation of a fully closed real time PCR platform for the detection of SARS-CoV-2 in nasopharyngeal swabs: a pilot study	6
Validity of whole genomes sequencing results in neoplasms in precision medicine	5
Recurrence prediction for breast phyllodes tumours: validation of the Singapore nomogram in Korean women	5
High-sensitivity cardiac troponin I: is ethnicity relevant?	5
Determination of cerebrospinal fluid adenosine deaminase activity cut-off for the diagnosis of tuberculous meningitis in Hong Kong	5
Macroscopic examination of pathology specimens: a critical reappraisal	5
Historical perspectives in clinical pathology: Bence Jones protein—early urine chemistry and the impact on modern day diagnostics	5
Clinical relevance of the in situ assay for HBV DNA: a cross-sectional study in patients with chronic hepatitis B	5
Artificial intelligence in pathology and laboratory medicine	5
Comparison of assessment of programmed death-ligand 1 (PD-L1) status in triple-negative breast cancer biopsies and surgical specimens	5
Nuclear-specific accumulation of telomerase reverse transcriptase (TERT) mRNA in TERT promoter mutated follicular thyroid tumours visualised by in situ hybridisation: a possible c	5
Overexpression of integrin alpha 2 (ITGA2) correlates with poor survival in patients with pancreatic ductal adenocarcinoma	5
Improving the management of early colorectal cancers (eCRC) by using quantitative markers to predict lymph node involvement and thus the need for major resection of pT1 cancers	5
Acute kidney injury caused by COVID-19 in a patient with Crohn’s disease treated with adalimumab	5
Performance evaluation of a fully closed real-time PCR platform for the detection of KRAS p.G12C mutations in liquid biopsy of patients with non-small cell lung cancer	5
Moving towards a local testing solution for undetermined thyroid fine-needle aspirates: validation of a novel custom DNA-based NGS panel	5
Development, internal validation and calibration of a risk score to predict survival in patients with EGFR-mutant non-small cell lung cancer	5
Pitfalls in the diagnosis of lentigo maligna and lentigo maligna melanoma, facts and an opinion	5
Does histological assessment accurately distinguish separate primary lung adenocarcinomas from intrapulmonary metastases? A study of paired resected lung nodules in 32 patients using a routine next-ge	5
Applications of machine learning in the chemical pathology laboratory	5
Cribriform colon cancer: a morphological growth pattern associated with extramural venous invasion, nodal metastases and microsatellite stability	5
Non-amplification genetic alterations ofHER2gene in non-small cell lung carcinoma	5
Cytogenetic complexity and heterogeneity in intravascular lymphoma	5