Journal of Clinical Pathology

Article	Citations
Histopathological observations in COVID-19: a systematic review	128
Protein tyrosine phosphatase receptor type C (PTPRC or CD45)	109
Gene of the month:TMPRSS2(transmembrane serine protease 2)	78
Current and future applications of artificial intelligence in pathology: a clinical perspective	62
COVID-19 salivary signature: diagnostic and research opportunities	61
PD-L1 expression by Tumor Proportion Score (TPS) and Combined Positive Score (CPS) are similar in non-small cell lung cancer (NSCLC)	60
Diagnostic concordance and discordance in digital pathology: a systematic review and meta-analysis	49
DNA mismatch repair proteins: scientific update and practical guide	38
Gene of the month: lymphocyte-activation gene 3 (LAG-3)	36
Gene of the month:DICER1:ruler and controller	30
Accuracy and stability of saliva as a sample for reverse transcription PCR detection of SARS-CoV-2	30
Placental microbial–metabolite profiles and inflammatory mechanisms associated with preterm birth	30
Platelet aggregates, a marker of severe COVID-19 disease	29
Molecular diagnosis in non-small-cell lung cancer: expert opinion onALKandROS1testing	29
Histopathological features of multiorgan percutaneous tissue core biopsy in patients with COVID-19	28
Low-grade oncocytic tumour expands the spectrum of renal oncocytic tumours and deserves separate classification: a review of 23 cases from a single tertiary institute	26
Cross-reactivity of SARS-CoV-2 with HIV chemiluminescent assay leading to false-positive results	25
Injuries and deaths from lightning	24
Carbonic anhydrase IX: a regulator of pH and participant in carcinogenesis	23
Future of biomarker evaluation in the realm of artificial intelligence algorithms: application in improved therapeutic stratification of patients with breast and prostate cancer	22
Molecules in pathogenesis: angiotensin converting enzyme 2 (ACE2)	22
Thyroid autoantibodies	21
Tumour immune microenvironment biomarkers predicting cytotoxic chemotherapy efficacy in colorectal cancer	21
Fibroblast growth factor receptor (FGFR) gene: pathogenesis and treatment implications in urothelial carcinoma of the bladder	20
High burden of acute kidney injury in COVID-19 pandemic: systematic review and meta-analysis	20

UK recommendations for HER2 assessment in breast cancer: an update	20
Homocystinuria diagnosis and management: it is not all classical	20
Assessment of mitotic activity in breast cancer: revisited in the digital pathology era	19
Rocky road to digital diagnostics: implementation issues and exhilarating experiences	19
Haemophagocytic lymphohistiocytosis after ChAdOx1 nCoV-19 vaccination	19
Variability in haemoglobin concentration by measurement tool and blood source: an analysis from seven countries	18
Hypophosphatasia	17
Adrenal insufficiency	17
IHC versus FISH versus NGS to detect ALK gene rearrangement in NSCLC: all questions answered?	17
Mutations inZP4are associated with abnormal zona pellucida and female infertility	16
Identification of potential crucial genes associated with the pathogenesis and prognosis of liver hepatocellular carcinoma	16
Secondary haemophagocytic lymphohistiocytosis in COVID-19: correlation of the autopsy findings of bone marrow haemophagocytosis with HScore	16
Diagnostic approach in TFE3-rearranged renal cell carcinoma: a multi-institutional international survey	15
Assessment of the effect of the COVID-19 pandemic on UK HbA1c testing: implications for diabetes management and diagnosis	15
Gene of the month: FH	15
Idylla microsatellite instability assay versus mismatch repair immunohistochemistry: a retrospective comparison in gastric adenocarcinoma	14
Best practice for LDL-cholesterol: when and how to calculate	14
Specific cell differentiation in breast cancer: a basis for histological classification	13
Gene of the month:GTF2I	12
Diagnostic performance of melanocytic markers for immunocytochemical evaluation of lymph-node melanoma metastases on cytological samples	12
Industry payments to pathologists in the USA between 2013 and 2021	12
Hypertriglyceridaemia: an update	12
Mutational profiling in suspected triple-negative essential thrombocythaemia using targeted next-generation sequencing in a real-world cohort	12
Evaluation of an open-source machine-learning tool to quantify bone marrow plasma cells	12
Real-world biomarker testing rate and positivity rate in NSCLC in Spain: Prospective Central Lung Cancer Biomarker Testing Registry (LungPath) from the Spanish Society of Pathology (SEAP)	11
Molecular characterisation of pancreatic ductal adenocarcinoma withNTRKfusions and review of the literature	11
Extended storage of SARS-CoV-2 nasopharyngeal swabs does not negatively impact results of molecular-based testing across three clinical platforms	11
Accuracy of GPT-4 in histopathological image detection and classification of colorectal adenomas	11
Frequency of microsatellite instability (MSI) in upper tract urothelial carcinoma: comparison of the Bethesda panel and the Idylla MSI assay in a consecutively collected, multi-institutional cohort	11
Gene of the month: TFE 3	11
Real-world digital pathology: considerations and ruminations of four young pathologists	11
Laboratory parameters in patients with COVID-19 on first emergency admission is different in non-survivors: albumin and lactate dehydrogenase as risk factors	11
Prevalence of mismatch repair deficiency and Lynch syndrome in a cohort of unselected small bowel adenocarcinomas	11
Clinicopathological characteristics and genetic variations of uterine tumours resembling ovarian sex cord tumours	11
Update on the current opinion, status and future development of digital pathology in Switzerland in light of COVID-19	11
Implementing NGS-basedBRCAtumour tissue testing in FFPE ovarian carcinoma specimens: hints from a real-life experience within the framework of expert recommendations	10
Significance of adenosquamous proliferation in breast lesions	10
Molecular classification of endometrial carcinoma: a clinically oriented review	10
Performance evaluation of the Biocartis Idylla EGFR Mutation Test using pre-extracted DNA from a cohort of highly characterised mutation positive samples	10
Adequacy of small biopsy and cytology specimens for comprehensive genomic profiling of patients with non-small-cell lung cancer to determine eligibility for immune checkpoint inhibitor and targeted th	10
Brain autopsies in fatal COVID-19 and postulated pathophysiology: more puzzling than a Rubik’s cube	10
Atypical lymphoid cells circulating in blood in COVID-19 infection: morphology, immunophenotype and prognosis value	10
Pathologists can get it right the first time	10
Abnormal umbilical cord insertions in singleton deliveries: placental histology and neonatal outcomes	10
Performance of the CellaVision DC-1 digital cell imaging analyser for differential counting and morphological classification of blood cells	10
Positivity for SATB2 distinguishes Islet1 positive rectal neuroendocrine tumours from pancreaticoduodenal neuroendocrine tumours	10
Gene of the month: T-cell immunoreceptor with immunoglobulin and ITIM domains (TIGIT)	9
Kinetics of SARS-CoV-2 antibody responses pre-COVID-19 and post-COVID-19 convalescent plasma transfusion in patients with severe respiratory failure: an observational case–control study	9
Cytokeratin 18 cell death assays as biomarkers for quantification of apoptosis and necrosis in COVID-19: a prospective, observational study	9
Unique correlation between GTF2I mutation and spindle cell morphology in thymomas (type A and AB thymomas)	9

Gene of the month: H3F3A and H3F3B	9
Mid-regional proadrenomedullin (MR-proADM), C-reactive protein (CRP) and other biomarkers in the early identification of disease progression in patients with COVID-19 in the acute NHS setting	9
Correlation between circulating blood and microenvironment T lymphocytes in diffuse large B-cell lymphomas	9
Gene of the month:STK11	9
Immunoinformatic approach to assess SARS-CoV-2 protein S epitopes recognised by the most frequent MHC-I alleles in the Brazilian population	9
Reference standards for gene fusion molecular assays on cytological samples: an international validation study	9
Short history of 5-methylcytosine: from discovery to clinical applications	9
Cost analysis of archives in the pathology laboratories: from safety to management	9
Prognostic values of L-type amino acid transporter 1 and CD98hc expression in breast cancer	9
Impact of COVID-19 on small biopsy diagnostic procedures and cancer resection surgeries in the North-West of Ireland	8
Integration of rapid PCR testing as an adjunct to NGS in diagnostic pathology services within the UK: evidence from a case series of non-squamous, non-small cell lung cancer (NSCLC) patients with foll	8
Antibody response and self-reported adverse reactions following vaccination with Comirnaty: a pilot study from a Croatian university hospital	8
Correlation of BRAF mutational status with clinical characteristics and survival outcomes of patients with ameloblastoma: the experience of 11 Italian centres	8
Pathology training in the age of artificial intelligence	8
Soluble type immune checkpoint regulators using multiplex luminex immunoassay in chronic hepatitis B patients	8
Clinicopathological predictors of survival in resected primary lung adenocarcinoma	8
CXCR4/ACKR3/CXCL12 axis in the lymphatic metastasis of vulvar squamous cell carcinoma	8
Faster than light (microscopy): superiority of digital pathology over microscopy for assessment of immunohistochemistry	8
MDM2 gene amplification as selection tool for innovative targeted approaches in PD-L1 positive or negative muscle-invasive urothelial bladder carcinoma	8
Expression, assessment and significance of Ki67 expression in breast cancer: an update	8
Three-antibody classifier for muscle invasive urothelial carcinoma and its correlation with p53 expression	8
Quantitative morphometrics reveals glomerular changes in patients with infrequent segmentally sclerosed glomeruli	8
Clinicopathological significance of neutrophil-rich colorectal carcinoma	7
PTEN as a target in melanoma	7
Pathology of IgG4-related sclerosing mastitis	7
Fostering intrinsic motivation in remote undergraduate histopathology education	7
Public perceptions on pathology: a fundamental change is required	7
Biochemical assessment of adequate levothyroxine replacement in primary hypothyroidism differs with different TSH assays: potential clinical implications	7
Clinical and laboratory characteristics in outpatient diagnosis of COVID-19 in healthcare professionals in Rio de Janeiro, Brazil	7
Comparative clinicopathological and immunohistochemical study of micronodular thymoma and micronodular thymic carcinoma with lymphoid stroma	7
Advanced pathological study for definite diagnosis of mitochondrial cardiomyopathy	7
Construction of a reference material panel for detectingKRAS/NRAS/EGFR/BRAF/METmutations in plasma ctDNA	7
Expression of YAP1 and pSTAT3-S727 and their prognostic value in glioma	7
Drug-induced hyperammonaemia	7
Moving towards a local testing solution for undetermined thyroid fine-needle aspirates: validation of a novel custom DNA-based NGS panel	7
Compound computer vision workflow for efficient and automated immunohistochemical analysis of whole slide images	7
Ethnicity influences total serum vitamin B12concentration: a study of Black, Asian and White patients in a primary care setting	7
Neuroendocrine tumours of the breast: a genomic comparison with mucinous breast cancers and neuroendocrine tumours of other anatomic sites	7
Expression and clinical significance of a new neuroendocrine marker secretagogin in cervical neuroendocrine carcinoma	7
High-sensitivity cardiac troponin I: is ethnicity relevant?	7
Gene of the month: NKX3.1	7
Liquid biopsy forBRAFmutations testing in non-small cell lung cancer: a retrospective study	7
Morphological control for molecular testing: a practical approach	7
Microsatellite instability evaluation: which test to use for endometrial cancer?	6
HER2-low in gastro-oesophageal adenocarcinoma: a real-world pathological perspective	6
Improved pathology reporting in NAFLD/NASH for clinical trials	6
Five simple reasons to discard DIP, or why we should stop calling dolphins big fish	6
Cytogenetic complexity and heterogeneity in intravascular lymphoma	6
Expression and correlation analysis of Skp2 and CBX7 in cervical cancer	6
Expression of the immunoproteasome subunit β5i in non-small cell lung carcinomas	6
Cancer-associated fibroblasts (CAFs) in thyroid papillary carcinoma: molecular networks and interactions	6
Macroscopic examination of pathology specimens: a critical reappraisal	6
BAP1-deficient meningioma presenting with trabecular architecture and cytokeratin expression: a report of two cases and review of the literature	6
Evaluation of a fully closed real time PCR platform for the detection of SARS-CoV-2 in nasopharyngeal swabs: a pilot study	6
Difficulties in diagnostics of lung tumours in biopsies: an interpathologist concordance study evaluating the international diagnostic guidelines	6
High case fatality rate in individuals with Down syndrome and COVID-19 in Brazil: a two-year report	6
Comparison between 1973 and 2004/2016 WHO grading systems in patients with Ta urothelial carcinoma of urinary bladder	6
Applications of machine learning in the chemical pathology laboratory	6
Cribriform colon cancer: a morphological growth pattern associated with extramural venous invasion, nodal metastases and microsatellite stability	6
Gene of the month:TLE 1	6
In-house homologous recombination deficiency testing in ovarian cancer: a multi-institutional Italian pilot study	6
Clinicopathologic characteristics of HER2-positive metaplastic squamous cell carcinoma of the breast	6
Improving the management of early colorectal cancers (eCRC) by using quantitative markers to predict lymph node involvement and thus the need for major resection of pT1 cancers	6
Does histological assessment accurately distinguish separate primary lung adenocarcinomas from intrapulmonary metastases? A study of paired resected lung nodules in 32 patients using a routine next-ge	5
TargetPlex FFPE-Direct DNA Library Preparation Kit for SiRe NGS panel: an international performance evaluation study	5
Mitochondrial molecular genetic results in a South African cohort: divergent mitochondrial and nuclear DNA findings	5
Clinicopathological and genetic analyses of pulmonary enteric adenocarcinoma	5
Beyond the routine CBC: machine learning and statistical analyses identify research CBC parameter associations with myelodysplastic syndromes and specific underlying pathogenic variants	5
Multi-gene custom panels for the characterisation of metastatic colorectal carcinoma in clinical practice: express the role ofPIK3CAmutations	5
Development of a LAG-3 immunohistochemistry assay for melanoma	5
MMR profile and microsatellite instability status in colorectal mucinous adenocarcinoma with synchronous metastasis: a new clue for the clinical practice	5
Update on the diagnosis and management of the autosomal dominant acute hepatic porphyrias	5
Dasatinib-induced Crohn’s-like colitis	5
Performance evaluation of a fully closed real-time PCR platform for the detection of KRAS p.G12C mutations in liquid biopsy of patients with non-small cell lung cancer	5
Ranking of journals by journal impact factors is not exact and may provoke misleading conclusions	5
Novel pathogenic variant c.2714C>A (p. Thr905Lys) in theHK1gene causing severe haemolytic anaemia with developmental delay in an Indian family	5
Investigation and monitoring of heavy metal poisoning	5
Validity of whole genomes sequencing results in neoplasms in precision medicine	5
Agreement between L1 and E6/E7-based assays for detection of high-risk HPV in cervical, oropharyngeal and penile cancers	5
Recurrence prediction for breast phyllodes tumours: validation of the Singapore nomogram in Korean women	5

IdyllaEGFRassay on extracted DNA: advantages, limits and place in molecular screening according to the latest guidelines for non-small-cell lung cancer (NSCLC) patients	5
Overexpression of integrin alpha 2 (ITGA2) correlates with poor survival in patients with pancreatic ductal adenocarcinoma	5
Development of a qualitative real-time RT-PCR assay for the detection of SARS-CoV-2: a guide and case study in setting up an emergency-use, laboratory-developed molecular microbiological assay	5
Co-occurring IPMN and pancreatic cancer: the same or different? An overview from histology to molecular pathology	5
Acute kidney injury caused by COVID-19 in a patient with Crohn’s disease treated with adalimumab	5
Circulating IL-6 is associated with disease progression in BRAFwt metastatic melanoma patients receiving anti-PD-1 therapy	5
Artificial intelligence in pathology and laboratory medicine	5
Nuclear-specific accumulation oftelomerase reverse transcriptase(TERT) mRNA inTERTpromoter mutated follicular thyroid tumours visualised by in situ hybridisation: a possible clini	5
Pitfalls in the diagnosis of lentigo maligna and lentigo maligna melanoma, facts and an opinion	5
Genes of the month: H3.3 histone genes: H3F3A and H3F3B	5
Liver involvement in patients with coeliac disease: proof of causality using IgA/anti-TG2 colocalisation techniques	4
Paediatric non-alcoholic fatty liver disease: an approach to pathological evaluation	4
Characterisation of antithrombin-dependent anticoagulants through clot waveform analysis to potentially distinguish them from antithrombin-independent inhibitors targeting activated coagulation factor	4
Towards better understanding of giant cell granulomas of the oral cavity	4
Morphological subtypes of colorectal low-grade intraepithelial neoplasia: diagnostic reproducibility, frequency and clinical impact	4
Decline of case reports in pathology and their renewal in the digital age: an analysis of publication trends over four decades	4
Blunt duct adenosis: a separate entity from columnar cell lesions?	4
High frequency ofPIK3CAandTERTpromoter mutations in fibromatosis-like spindle cell carcinomas	4
Challenging of frozen diagnoses of small sclerosing pneumocytoma	4
Biomarker testing strategies in non-small cell lung cancer in the real-world setting: analysis of methods in the Prospective Central Lung Cancer Biomarker Registry (LungPath) from the Spanish Society	4
Critical role of diagnostic SARS-CoV-2 T cell assays for immunodeficient patients	4
SSTR2a is constantly expressed in lymphoepithelioma-like carcinoma with squamous differentiation other than that with glandular differentiation	4
FGFR1copy number in breast cancer: associations with proliferation, histopathological grade and molecular subtypes	4
Postmortem survey of haemoglobin A1c, non-alcoholic steatohepatitis and liver fibrosis within a general population	4
Implementation of an ISO15189 accredited next-generation sequencing service with the fully automated Ion Torrent Genexus: the experience of a clinical diagnostic laboratory	4
Spatial resolution of renal amyloid deposits through MALDI-MSI: a combined digital and molecular approach to monoclonal gammopathies	4
Novel histological repertoire of crypt-associated anomalies in inflamed colon mucosa	4
Adiponectin and adiponectin receptor 1 expression proteins levels are modified in breast cancer in postmenopausal women with obesity	4
Gene of the month: GATA3	4
Defining invasion in breast cancer: the role of basement membrane	4
Role of PRPS2 as a prognostic and therapeutic target in osteosarcoma	4
Idylla MSI test as a new tool for microsatellite instability detection in sebaceous tumours and keratoacanthomas	4
Histological background of dedifferentiated solitary fibrous tumour	4
‘Test, test, test’ even after death: persistence of SARS-CoV-2 RNA in postmortem nasopharyngeal swabs	4
PAX6is frequently expressed in ependymal tumours and associated with prognostic relevant subgroups	4
GATA3 positivity is associated with poor prognosis in patients with oesophageal squamous cell carcinoma	4
Educational cost-effective intervention to reduce pathologist’s peripheral blood smears reviews with non-contributory findings: an academic institution experience	4
Which classification system defines best prognosis of mucinous neoplasms of the appendix with peritoneal dissemination: TNM vs PSOGI?	4
Unravelling the USP6 gene: an update	4
Comparison of assessment of programmed death-ligand 1 (PD-L1) status in triple-negative breast cancer biopsies and surgical specimens	4
Adipophilin expression in skin lesions with clear cell histology	4
Association between faecal occult bleeding and medicines prescribed for chronic disease: a data linkage study	4
Low interobserver agreement among subspecialised breast pathologists in evaluating HER2-low breast cancer	4
Primary hepatic follicular lymphoma 5 years post sustained virological response from hepatitis C viral infection	3
Putrefaction in the pandemic: a comparative study of the frequency of advanced decomposition change in coronial autopsies since the start of the COVID-19 pandemic	3
Emerging mesenchymal tumour types and biases in the era of ubiquitous sequencing	3
Validation of multiplex immunofluorescence and digital image analysis for programmed death-ligand 1 expression and immune cell assessment in non-small cell lung cancer: comparison with conventional im	3
Monitoring the SPREAD of the SARS-CoV-2 lineage B.1.621 in Udine, Italy	3
Pilot study investigating diagnostic utility of serum MMP-1 and TGF-β1 in asthma in ‘real world’ clinical practice in India	3
Ran GTPase is an independent prognostic marker in malignant melanoma which promotes tumour cell migration and invasion	3
Multicentric evaluation of analytical performances digital morphology with respect to the reference methods by manual optical microscopy	3
Real-time EndoFaster improvesHelicobacter pyloridetection in chronic active gastritis	3
Nuclear staining for pan-Trk by immunohistochemistry is highly specific for secretory carcinoma of breast: pan-Trk in various subtypes of breast carcinoma	3
Optimised architecture-based grading system as an independent prognostic factor in resected lung adenocarcinoma	3
Using Systemised Nomenclature of Medicine (SNOMED) codes to select digital pathology whole slide images for long-term archiving	3
Asymmetric crypt fission in colectomy specimens in patients with ulcerative colitis	3
Integration of computer-aided automated analysis algorithms in the development and validation of immunohistochemistry biomarkers in ovarian cancer	3
Expression of p16Ink4aprotein in pleomorphic adenoma and carcinoma ex pleomorphic adenoma proves diversity of tumour biology and predicts clinical course	3
Actinic keratoses contiguous with squamous cell carcinomas are mostly non-hyperkeratotic and with severe dysplasia	3
Sinusoidal dilatation and congestion in post-transplant liver biopsies from patients presenting with transaminitis	3
Genomic landscape of colorectal carcinoma in sub-Saharan Africa	3
Exciting experiences in the ‘Rocky road to digital diagnostics’	3
Reliability and reproducibility among different platforms for tumour BRCA testing in ovarian cancer: a study of the Italian NGS Network	3
Caveolin-1 expression predicts favourable outcome and correlates withPDGFRAmutations in gastrointestinal stromal tumours (GISTs)	3
Plasma viscosity, immunoglobulins and risk of cardiovascular disease and mortality: new data and meta-analyses	3
Lights on HBME-1: the elusive biomarker in thyroid cancer pathology	3
Rapid serum clot tubes reduce haemolysis due to pneumatic tube transport	3
Validation of the reticulocyte channel of Sysmex XN-9000 system for blood cell count in samples with suspected cold agglutination for use in a total laboratory automation setting	3
Megarectum: systematic histopathological evaluation of 35 patients and new common pathways in chronic rectal dilatation	3
New kids on the block:FOSandFOSBgene	3
Low expression of DDX5 is associated with poor prognosis in patients with pancreatic ductal adenocarcinoma	3
Survey of liver pathologists to assess attitudes towards digital pathology and artificial intelligence	3
Chondroblastoma: clinicopathological analyses of 307 cases from a single institution in China and the diagnostic value of the H3F3 K36M mutant antibody	3
Improving precise counting of mitotic cells in mantle cell lymphoma using phosphohistone H3 (PHH3) antibody	3
Letter to the editor: additional evidence to support a cross-reactivity of SARS-CoV-2 with HIV chemiluminescent assay	3
Histopathology reporting of temporal artery biopsy specimens for giant cell arteritis: results of a modified Delphi study	3
IGHcytogenetic abnormalities can be detected in multiple myeloma by imaging flow cytometry	3
Gene of the month: Cornulin	3
Macroscopic pathology and all that: a personal view	3
Validation of the Residual Cancer Burden Index as a prognostic tool in women with locally advanced breast cancer treated with neoadjuvant chemotherapy	3
Highly differentiated follicular thyroid-type carcinoma of the ovary reconsidered	3
Confirming anaphylaxis postmortem using serodiagnostic tests	3
Essentials of macroscopic evaluation of specimens from gastrointestinal tract	3
Thrombin generation assay and lupus anticoagulant synergically distinguish populations of patients with antiphospholipid antibodies	3
KITgenetic alterations in breast cancer	3
Prognostic significance of heat shock protein 90AA1 (HSP90α) in invasive breast cancer	3
Macroscopy of specimens from the genitourinary system	3
Genetic associations with polycystic ovary syndrome: the role of the mitochondrial genome; a systematic review and meta-analysis	3
Non-Wilsonian copper toxicity: more questions than answers	3
Impact of the COVID-19 pandemic on cytopathology services in the West of Ireland	3
Tissue methylation and demethylation influence translesion synthesis DNA polymerases (TLS) contributing to the genesis of chromosomal abnormalities in myelodysplastic syndrome	3
Ethics in clinical autopsy	3
Results of histopathological revisions of major salivary gland neoplasms in routine clinical practice	3
Adipophilin: roles in physiology and pathology	3
Molecular heterogeneity of pancreatic intraductal papillary mucinous neoplasms and implications for novel endoscopic tissue sampling strategies	3