OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Clinical Investigation is 56. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-03-01 to 2025-03-01.)

Article	Citations
Changes in the National Cancer Institute’s R01 workforce: growth, aging, retention, and policy implications	224
Remodeling glycerophospholipids affects obesity-related insulin signaling in skeletal muscle	208
CC17 group B Streptococcus exploits integrins for neonatal meningitis development	196
An abundant biliary metabolite derived from dietary omega-3 polyunsaturated fatty acids regulates triglycerides	172
Lysophospholipid acylation modulates plasma membrane lipid organization and insulin sensitivity in skeletal muscle	146
Renal tubule Cpt1a overexpression protects from kidney fibrosis by restoring mitochondrial homeostasis	127
IRF3 reduces adipose thermogenesis via ISG15-mediated reprogramming of glycolysis	119
A replication-competent adenovirus-vectored influenza vaccine induces durable systemic and mucosal immunity	110
Integrating imaging and RNA-seq improves outcome prediction in cervical cancer	102
Inhibiting the MNK1/2-eIF4E axis impairs melanoma phenotype switching and potentiates antitumor immune responses	101
Identification of SARS-CoV-2–specific immune alterations in acutely ill patients	92
Age-specific effects of vaccine egg adaptation and immune priming on A(H3N2) antibody responses following influenza vaccination	85
VCAM-1: closing the gap between lipotoxicity and endothelial dysfunction in nonalcoholic steatohepatitis	85
Plasma cells promote osteoclastogenesis and periarticular bone loss in autoimmune arthritis	78
SUMOylation promotes extracellular vesicle–mediated transmission of lncRNA ELNAT1 and lymph node metastasis in bladder cancer	78
A sobering addition to the literature on COVID-19 and the brain	76
NOD2 drives early IL-33–dependent expansion of group 2 innate lymphoid cells during Crohn’s disease–like ileitis	75
Targeting a Braf/Mapk pathway rescues podocyte lipid peroxidation in CoQ-deficiency kidney disease	74
Endoplasmic reticulum stress sensor IRE1α propels neutrophil hyperactivity in lupus	69
Satellite glial GPR37L1 and its ligand maresin 1 regulate potassium channel signaling and pain homeostasis	68
America’s deadly flirtation with antiscience and the medical freedom movement	67
Concerted roles of PTEN and ATM in controlling hematopoietic stem cell fitness and dormancy	66
TorsinA restoration in a mouse model identifies a critical therapeutic window for DYT1 dystonia	65
Lymphohematopoietic graft-versus-host responses promote mixed chimerism in patients receiving intestinal transplantation	65
Metabolic rerouting via SCD1 induction impacts X-linked adrenoleukodystrophy	63

Long-term microstructure and cerebral blood flow changes in patients recovered from COVID-19 without neurological manifestations	63
A conversation with Robert Lefkowitz	56
Endoplasmic reticulum–associated degradation is required for nephrin maturation and kidney glomerular filtration function	56