Journal of Cell Science

Article	Citations
Microautophagy – distinct molecular mechanisms handle cargoes of many sizes	200
Mammalian stress granules and P bodies at a glance	195
The myofibroblast at a glance	166
The cell biologist's guide to super-resolution microscopy	102
Histone variants at a glance	99
Autophagy and endocytosis – interconnections and interdependencies	81
HECT E3 ubiquitin ligases – emerging insights into their biological roles and disease relevance	67
Motor proteins at the mitochondria–cytoskeleton interface	60
Bacterial cell division at a glance	59
Biomechanical regulation of focal adhesion and invadopodia formation	56
Recent insights into the regulatory networks of NLRP3 inflammasome activation	56
Fueling the cytoskeleton – links between cell metabolism and actin remodeling	55
The importance of water and hydraulic pressure in cell dynamics	54
Mitochondrial dynamics during spermatogenesis	52
Cargo transport through the nuclear pore complex at a glance	52
ADAMTS-1 and syndecan-4 intersect in the regulation of cell migration and angiogenesis	52
The ESCRTs – converging on mechanism	51
The basement membrane as a structured surface – role in vascular health and disease	51
The formin inhibitor SMIFH2 inhibits members of the myosin superfamily	49
p63-related signaling at a glance	48
Endoplasmic reticulum–mitochondria signaling in neurons and neurodegenerative diseases	43
Extracellular vesicles – propagators of neuropathology and sources of potential biomarkers and therapeutics for neurodegenerative diseases	43
The osteoclast cytoskeleton – current understanding and therapeutic perspectives for osteoporosis	42
Talin in mechanotransduction and mechanomemory at a glance	41
The diverse roles and dynamic rearrangement of vimentin during viral infection	41

Recent insights into peroxisome biogenesis and associated diseases	40
A guide to accurate reporting in digital image processing – can anyone reproduce your quantitative analysis?	38
Notch in mechanotransduction – from molecular mechanosensitivity to tissue mechanostasis	38
The structural basis of intraflagellar transport at a glance	38
Squaring the EMC – how promoting membrane protein biogenesis impacts cellular functions and organismal homeostasis	38
Atypical basement membranes and basement membrane diversity – what is normal anyway?	37
Dynamic and cell-specific transport networks for intracellular copper ions	37
The multifaceted functions of ATG16L1 in autophagy and related processes	35
Ena/VASP proteins in cell edge protrusion, migration and adhesion	35
Brain endothelial tricellular junctions as novel sites for T cell diapedesis across the blood–brain barrier	35
αvβ8 integrin adhesion and signaling pathways in development, physiology and disease	35
A possible role for VPS13-family proteins in bulk lipid transfer, membrane expansion and organelle biogenesis	34
Non-caveolar caveolins – duties outside the caves	34
The UPRosome – decoding novel biological outputs of IRE1α function	33
New insights into non-transcriptional regulation of mammalian core clock proteins	33
Protein phosphatase 2A – structure, function and role in neurodevelopmental disorders	33
Science during lockdown – from virtual seminars to sustainable online communities	33
Rhodopsins at a glance	33
Quantitative intravital imaging in zebrafish reveals in vivo dynamics of physiological-stress-induced mitophagy	33
A guide to accurate reporting in digital image acquisition – can anyone replicate your microscopy data?	32
Upregulation of APP endocytosis by neuronal aging drives amyloid-dependent synapse loss	32
Molecular basis for KDEL-mediated retrieval of escaped ER-resident proteins – SWEET talking the COPs	31
Neutral sphingomyelinase 2 controls exosome secretion by counteracting V-ATPase-mediated endosome acidification	31
Visualizing endogenous Rho activity with an improved localization-based, genetically encoded biosensor	30
Let's get physical – mechanisms of crossover interference	30
The appressorium at a glance	29
Vimentin tunes cell migration on collagen by controlling β1 integrin activation and clustering	29
The flipside of the TOR coin – TORC2 and plasma membrane homeostasis at a glance	29
Diverse cellular functions of barrier-to-autointegration factor and its roles in disease	29
Molecular models of LINC complex assembly at the nuclear envelope	28
The evolution of autophagy proteins – diversification in eukaryotes and potential ancestors in prokaryotes	28
Translation initiation in cancer at a glance	28
Tensins – emerging insights into their domain functions, biological roles and disease relevance	28
PDZD8-mediated lipid transfer at contacts between the ER and late endosomes/lysosomes is required for neurite outgrowth	28
Hypothesis-driven quantitative fluorescence microscopy – the importance of reverse-thinking in experimental design	28
FGF2 and IL-1β – explorers of unconventional secretory pathways at a glance	28
Pericyte mechanics and mechanobiology	28
In vivo imaging shows continued association of several IFT-A, IFT-B and dynein complexes while IFT trains U-turn at the tip	27
Condensation of pericentrin proteins in human cells illuminates phase separation in centrosome assembly	27
Role of the Sec22b–E-Syt complex in neurite growth and ramification	27
Ipomoeassin-F inhibits the in vitro biogenesis of the SARS-CoV-2 spike protein and its host cell membrane receptor	27
The oncogenic transcription factor FUS-CHOP can undergo nuclear liquid–liquid phase separation	27
Ferroptosis induces membrane blebbing in placental trophoblasts	27
mRNA distribution in skeletal muscle is associated with mRNA size	27
Natural killer cell immune synapse formation and cytotoxicity are controlled by tension of the target interface	27
The phosphatidylinositol 3-phosphate-binding protein SNX4 controls ATG9A recycling and autophagy	26
The role of Mfn2 in the structure and function of endoplasmic reticulum-mitochondrial tethering in vivo	26
Mammalian copper homeostasis requires retromer-dependent recycling of the high-affinity copper transporter 1	26
Accessory proteins of the zDHHC family of S-acylation enzymes	25
Compartmentalization and metabolic regulation of glycolysis	25

Evolution and insights into the structure and function of the DedA superfamily containing TMEM41B and VMP1	25
Characterization of the novel mitochondrial genome segregation factor TAP110 in Trypanosoma brucei	25
An endometrial organoid model of interactions between Chlamydia and epithelial and immune cells	25
CLASPs at a glance	25
The journey of Ca2+ through the cell – pulsing through the network of ER membrane contact sites	24
L-selectin regulates human neutrophil transendothelial migration	24
LFA-1 signals to promote actin polymerization and upstream migration in T cells	24
On the asymmetric partitioning of nucleocytoplasmic transport – recent insights and open questions	24
A glucose-starvation response governs endocytic trafficking and eisosomal retention of surface cargoes in budding yeast	23
The pleiotropic functions of autophagy in metastasis	23
Perilipins at a glance	23
Nuclear speckles – a driving force in gene expression	23
Regulation of hemidesmosome dynamics and cell signaling by integrin α6β4	22
Acute inactivation of retromer and ESCPE-1 leads to time-resolved defects in endosomal cargo sorting	22
α-Arrestin ARRDC3 tumor suppressor function is linked to GPCR-induced TAZ activation and breast cancer metastasis	22
Neutrophil transendothelial migration hotspots – mechanisms and implications	22
Ras, PI3K and mTORC2 – three's a crowd?	22
Centrosome maturation – in tune with the cell cycle	21
Frustrated clathrin-mediated endocytosis – causes and possible functions	21
Rab11 is required for lysosome exocytosis through the interaction with Rab3a, Sec15 and GRAB	21
Lipophagy at a glance	21
Forcing a growth factor response – tissue-stiffness modulation of integrin signaling and crosstalk with growth factor receptors	20
New insights into FAK structure and function in focal adhesions	20
A three-organelle complex made by wrappER contacts with peroxisomes and mitochondria responds to liver lipid flux changes	20
Ribosome quality control activity potentiates vaccinia virus protein synthesis during infection	20
Luminescence lifetime imaging of three-dimensional biological objects	20
Combined heterogeneity in cell size and deformability promotes cancer invasiveness	20
It takes two to tango – molecular links between plant immunity and brassinosteroid signalling	20
Emerging functions of cytoskeletal proteins in immune diseases	19
Malaria parasite egress at a glance	19
The canonical smooth muscle cell marker TAGLN is present in endothelial cells and is involved in angiogenesis	19
INPP5E controls ciliary localization of phospholipids and the odor response in olfactory sensory neurons	19
The pivotal role of ERp44 in patrolling protein secretion	19
TRP channels in health and disease at a glance	18
Physiological functions and roles in cancer of the proliferation marker Ki-67	18
Nuclear myosins – roles for molecular transporters and anchors	18
Phosphorylation of the AMPA receptor subunit GluA1 regulates clathrin-mediated receptor internalization	18
Spatial distribution of lamin A/C determines nuclear stiffness and stress-mediated deformation	18
Importin-9 regulates chromosome segregation and packaging in Drosophila germ cells	18
The Hob proteins are novel and conserved lipid-binding proteins at ER–PM contact sites	18
YAP, CTGF and Cyr61 are overexpressed in tamoxifen-resistant breast cancer and induce transcriptional repression of ERα	18
The tumor-suppressive long noncoding RNA DRAIC inhibits protein translation and induces autophagy by activating AMPK	18
Coordination of mitochondrial and cellular dynamics by the actin-based motor Myo19	18
Ribosome-associated quality control of membrane proteins at the endoplasmic reticulum	18
The p97–UBXN1 complex regulates aggresome formation	17
Interaction between VPS13A and the XK scramblase is important for VPS13A function in humans	17
Cytoskeletal mechanics and dynamics in the Drosophila syncytial embryo	17
Molecular insight into how γ-TuRC makes microtubules	17
A lamin A/C variant causing striated muscle disease provides insights into filament organization	17
Adenine nucleotide translocase regulates airway epithelial metabolism, surface hydration and ciliary function	17
Hydrostatic pressure prevents chondrocyte differentiation through heterochromatin remodeling	17
Tubulin isotypes – functional insights from model organisms	17
Circulating prostate cancer cells have differential resistance to fluid shear stress-induced cell death	17
Insights into animal septins using recombinant human septin octamers with distinct SEPT9 isoforms	17
Cellular metabolism in the defense against microbes	17
Maintenance of complex I and its supercomplexes by NDUF-11 is essential for mitochondrial structure, function and health	17
Mechanical and chemical activation of GPR68 probed with a genetically encoded fluorescent reporter	17
The Bardet–Biedl syndrome complex component BBS1 controls T cell polarity during immune synapse assembly	17
Cargo sorting at the trans-Golgi network at a glance	17
Identification of a heat-inducible novel nuclear body containing the long noncoding RNA MALAT1	17
Manipulation of selective macroautophagy by pathogens at a glance	17
The F1 loop of the talin head domain acts as a gatekeeper in integrin activation and clustering	17
Depletion of a Toxoplasma porin leads to defects in mitochondrial morphology and contacts with the endoplasmic reticulum	17
Trio family proteins as regulators of cell migration and morphogenesis in development and disease – mechanisms and cellular contexts	17
The role of icIL-1RA in keratinocyte senescence and development of the senescence-associated secretory phenotype	16
LRRC23 is a conserved component of the radial spoke that is necessary for sperm motility and male fertility in mice	16
Interplay between myofibers and pro-inflammatory macrophages controls muscle damage in mdx mice	16
Visualising the cytoskeletal machinery in neuronal growth cones using cryo-electron tomography	16
Hit the brakes – a new perspective on the loop extrusion mechanism of cohesin and other SMC complexes	16
Rab5 regulates macropinocytosis by recruiting the inositol 5-phosphatases OCRL and Inpp5b that hydrolyse PtdIns(4,5)P2	16
A novel function for Rab1 and Rab11 during secretory granule maturation	16
Turgor-dependent and coronin-mediated F-actin dynamics drive septin disc-to-ring remodeling in the blast fungus Magnaporthe oryzae	16
Differential cellular responses to adhesive interactions with galectin-8- and fibronectin-coated substrates	16
Blockage of bone morphogenetic protein signalling counteracts hypertrophy in a human osteoarthritic micro-cartilage model	16
Blood platelet formation at a glance	16
Coupling of dynamic microtubules to F-actin by Fmn2 regulates chemotaxis of neuronal growth cones	16
An optogenetic method for interrogating YAP1 and TAZ nuclear–cytoplasmic shuttling	16
Mitofusin 2 regulates neutrophil adhesive migration and the actin cytoskeleton	16
Sex differences in the proliferation of pulmonary artery endothelial cells: implications for plexiform arteriopathy	15
Direct evidence of cellular transformation by prion-like p53 amyloid infection	15

Isoform-dependent lysosomal degradation and internalization of apolipoprotein E requires autophagy proteins	15
IMC10 and LMF1 mediate mitochondrial morphology through mitochondrion–pellicle contact sites in Toxoplasma gondii	15
Enhanced RhoA signalling stabilizes E-cadherin in migrating epithelial monolayers	15
Membrane trafficking in the retinal pigment epithelium at a glance	15
Picornavirus 3C – a protease ensuring virus replication and subverting host responses	15
Control of assembly of extra-axonemal structures: the paraflagellar rod of trypanosomes	15
Ca2+ elevations disrupt interactions between intraflagellar transport and the flagella membrane in Chlamydomonas	15
FAM209 associates with DPY19L2, and is required for sperm acrosome biogenesis and fertility in mice	15
Large organellar changes occur during mild heat shock in yeast	15
Selective axonal translation of the mRNA isoform encoding prenylated Cdc42 supports axon growth	15
Intercellular and intracellular cilia orientation is coordinated by CELSR1 and CAMSAP3 in oviduct multi-ciliated cells	14
The lysosomotrope GPN mobilises Ca2+ from acidic organelles	14
Dissecting lipid droplet biology with coherent Raman scattering microscopy	14
Polarisome assembly mediates actin remodeling during polarized yeast and fungal growth	14
Shedding of ciliary vesicles at a glance	14
ADAR1 limits stress granule formation through both translation-dependent and translation-independent mechanisms	14
Fibroblastic reticular cell response to dendritic cells requires coordinated activity of podoplanin, CD44 and CD9	14
Advances on the roles of tenascin-C in cancer	14
S-acylation of Orai1 regulates store-operated Ca2+ entry	14
Chromosome–nuclear envelope tethering – a process that orchestrates homologue pairing during plant meiosis?	14
Ana1 helps recruit Polo to centrioles to promote mitotic PCM assembly and centriole elongation	14
A general role for TANGO1, encoded by MIA3, in secretory pathway organization and function	14
Data science in cell imaging	14
Near-infrared imaging in fission yeast using a genetically encoded phycocyanobilin biosynthesis system	14
Desmosome dualism – most of the junction is stable, but a plakophilin moiety is persistently dynamic	14
Structural model of human PORCN illuminates disease-associated variants and drug-binding sites	14
Emerging evidence for kindlin oligomerization and its role in regulating kindlin function	14
Bring it back, bring it back, don't take it away from me – the sorting receptor RER1	14
TORC1 and PKA activity towards ribosome biogenesis oscillates in synchrony with the budding yeast cell cycle	14
MyomiRs and their multifaceted regulatory roles in muscle homeostasis and amyotrophic lateral sclerosis	14
The ubiquitin-like modifier FAT10 – much more than a proteasome-targeting signal	14
Roles of the actin cytoskeleton in ciliogenesis	14
The prophase oocyte nucleus is a homeostatic G-actin buffer	13
Hijacking of the host cell Golgi by Plasmodium berghei liver stage parasites	13
Local translation in perisynaptic and perivascular astrocytic processes – a means to ensure astrocyte molecular and functional polarity?	13
The role of nuclear Ca2+ in maintaining neuronal homeostasis and brain health	13
Rab7b regulates dendritic cell migration by linking lysosomes to the actomyosin cytoskeleton	13
The actin cytoskeleton-MRTF/SRF cascade transduces cellular physical niche cues to entrain the circadian clock	13
The surface of lipid droplets constitutes a barrier for endoplasmic reticulum-resident integral membrane proteins	13
Fibronectin Extra Domains tune cellular responses and confer topographically distinct features to fibril networks	13
Chlamydomonas FAP70 is a component of the previously uncharacterized ciliary central apparatus projection C2a	13
Expression analysis and function of mitochondrial genome-encoded microRNAs	13
Genetic compensation for cilia defects in cep290 mutants by upregulation of cilia-associated small GTPases	13
Insight into the regulation of axonal transport from the study of KIF1A-associated neurological disorder	13
Cytoplasmic factories for axonemal dynein assembly	13
Innate immune receptor clustering and its role in immune regulation	13
Decoupling SARS-CoV-2 ORF6 localization and interferon antagonism	13
Lipid droplets form a network interconnected by the endoplasmic reticulum through which their proteins equilibrate	13
A dual role of YAP in driving TGFβ-mediated endothelial-to-mesenchymal transition	13
Lamellipodia-like actin networks in cells lacking WAVE regulatory complex	13
Non-canonical argonaute loading of extracellular vesicle-derived exogenous single-stranded miRNA in recipient cells	13
Stable tug-of-war between kinesin-1 and cytoplasmic dynein upon different ATP and roadblock concentrations	13
Cell-to-cell and genome-to-genome variability of adenovirus transcription tuned by the cell cycle	13
Dynamic remodeling of ribosomes and endoplasmic reticulum in axon terminals of motoneurons	13
EVI/WLS function is regulated by ubiquitylation and is linked to ER-associated degradation by ERLIN2	13
Evidence for macromolecular crowding as a direct apoptotic stimulus	13
Viral use and subversion of membrane organization and trafficking	12
Non-muscle myosin 2 at a glance	12
Emerging views of genome organization in Archaea	12
Emerin regulation of nuclear stiffness is required for fast amoeboid migration in confined environments	12
Emerging insights into serine/threonine-specific phosphoprotein phosphatase function and selectivity	12
Supply chain logistics – the role of the Golgi complex in extracellular matrix production and maintenance	12
Tyrosine kinase-independent actions of DDR2 in tumor cells and cancer-associated fibroblasts influence tumor invasion, migration and metastasis	12
Smaug1 membrane-less organelles respond to AMPK and mTOR and affect mitochondrial function	12
ApoE4 disrupts interaction of sortilin with fatty acid-binding protein 7 essential to promote lipid signaling	12
Concurrent depletion of Vps37 proteins evokes ESCRT-I destabilization and profound cellular stress responses	12
Identification of mutants with increased variation in cell size at onset of mitosis in fission yeast	12
Lysosomal TRPML1 regulates mitochondrial function in hepatocellular carcinoma cells	12
Vacuolar protein Tag1 and Atg1–Atg13 regulate autophagy termination during persistent starvation in S. cerevisiae	12
Single-cell imaging of ERK and Akt activation dynamics and heterogeneity induced by G-protein-coupled receptors	12
ULK1-mediated phosphorylation regulates the conserved role of YKT6 in autophagy	12
AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer	11
Cargo adapters expand the transport range of intraflagellar transport	11
DNAJB chaperones suppress destabilised protein aggregation via a region distinct from that used to inhibit amyloidogenesis	11
Dissecting the PRSS37 interactome and potential mechanisms leading to ADAM3 loss in PRSS37-null sperm	11
Rab11FIP1 maintains Rab35 at the intercellular bridge to promote actin removal and abscission	11
Bacteria- and host-derived extracellular vesicles – two sides of the same coin?	11
Selective microautophagy of proteasomes is initiated by ESCRT-0 and is promoted by proteasome ubiquitylation	11
Septin-microtubule association via a motif unique to isoform 1 of septin 9 tunes stress fibers	11
Regulation of kinesin-1 activity by the Salmonella enterica effectors PipB2 and SifA	11
Enrichment of Zα domains at cytoplasmic stress granules is due to their innate ability to bind to nucleic acids	11
Efficient genome editing by CRISPR-Mb3Cas12a in mice	11
Intracellular flow cytometric lipid analysis – a multiparametric system to assess distinct lipid classes in live cells	11
De novo formation of early endosomes during Rab5-to-Rab7a transition	11
An SNX10-dependent mechanism downregulates fusion between mature osteoclasts	11
Tumour-directed microenvironment remodelling at a glance	11
Mechanosensitive expression of lamellipodin promotes intracellular stiffness, cyclin expression and cell proliferation	11
Ultrastructure expansion microscopy reveals the cellular architecture of budding and fission yeast	11
Managing risky assets – mitophagy in vivo	11
When light meets biology – how the specimen affects quantitative microscopy	11
Regulation of hippocampal excitatory synapses by the Zdhhc5 palmitoyl acyltransferase	11
Organization and dynamics of the cortical complexes controlling insulin secretion in β-cells	11
Oncogenic gain of function due to p53 amyloids occurs through aberrant alteration of cell cycle and proliferation	11
Genome-wide imaging screen uncovers molecular determinants of arsenite-induced protein aggregation and toxicity	11
Chick cranial neural crest cells release extracellular vesicles that are critical for their migration	11