Journal of Cell Science

Article	Citations
Histone variants at a glance	122
Motor proteins at the mitochondria–cytoskeleton interface	74
Fueling the cytoskeleton – links between cell metabolism and actin remodeling	73
Recent insights into the regulatory networks of NLRP3 inflammasome activation	62
Cargo transport through the nuclear pore complex at a glance	60
Endoplasmic reticulum–mitochondria signaling in neurons and neurodegenerative diseases	55
Talin in mechanotransduction and mechanomemory at a glance	55
Dynamic and cell-specific transport networks for intracellular copper ions	51
The formin inhibitor SMIFH2 inhibits members of the myosin superfamily	51
Extracellular vesicles – propagators of neuropathology and sources of potential biomarkers and therapeutics for neurodegenerative diseases	50
The appressorium at a glance	46
The diverse roles and dynamic rearrangement of vimentin during viral infection	45
Visualizing endogenous Rho activity with an improved localization-based, genetically encoded biosensor	44
Notch in mechanotransduction – from molecular mechanosensitivity to tissue mechanostasis	43
Brain endothelial tricellular junctions as novel sites for T cell diapedesis across the blood–brain barrier	42
Nuclear speckles – a driving force in gene expression	42
Ena/VASP proteins in cell edge protrusion, migration and adhesion	42
A possible role for VPS13-family proteins in bulk lipid transfer, membrane expansion and organelle biogenesis	42
Protein phosphatase 2A – structure, function and role in neurodevelopmental disorders	42
The structural basis of intraflagellar transport at a glance	42
A guide to accurate reporting in digital image processing – can anyone reproduce your quantitative analysis?	39
Rhodopsins at a glance	39
Let's get physical – mechanisms of crossover interference	38
The role of Mfn2 in the structure and function of endoplasmic reticulum-mitochondrial tethering in vivo	35
Neutral sphingomyelinase 2 controls exosome secretion by counteracting V-ATPase-mediated endosome acidification	35

Upregulation of APP endocytosis by neuronal aging drives amyloid-dependent synapse loss	35
Quantitative intravital imaging in zebrafish reveals in vivo dynamics of physiological-stress-induced mitophagy	35
A guide to accurate reporting in digital image acquisition – can anyone replicate your microscopy data?	34
FGF2 and IL-1β – explorers of unconventional secretory pathways at a glance	34
Condensation of pericentrin proteins in human cells illuminates phase separation in centrosome assembly	34
Compartmentalization and metabolic regulation of glycolysis	33
PDZD8-mediated lipid transfer at contacts between the ER and late endosomes/lysosomes is required for neurite outgrowth	33
Molecular models of LINC complex assembly at the nuclear envelope	33
The oncogenic transcription factor FUS-CHOP can undergo nuclear liquid–liquid phase separation	32
Vimentin tunes cell migration on collagen by controlling β1 integrin activation and clustering	32
Natural killer cell immune synapse formation and cytotoxicity are controlled by tension of the target interface	32
Pericyte mechanics and mechanobiology	32
Perilipins at a glance	32
Tensins – emerging insights into their domain functions, biological roles and disease relevance	32
Physiological functions and roles in cancer of the proliferation marker Ki-67	31
The evolution of autophagy proteins – diversification in eukaryotes and potential ancestors in prokaryotes	31
mRNA distribution in skeletal muscle is associated with mRNA size	30
Characterization of the novel mitochondrial genome segregation factor TAP110 in Trypanosoma brucei	30
Ipomoeassin-F inhibits the in vitro biogenesis of the SARS-CoV-2 spike protein and its host cell membrane receptor	30
The phosphatidylinositol 3-phosphate-binding protein SNX4 controls ATG9A recycling and autophagy	30
Translation initiation in cancer at a glance	29
An endometrial organoid model of interactions between Chlamydia and epithelial and immune cells	29
Rab11 is required for lysosome exocytosis through the interaction with Rab3a, Sec15 and GRAB	29
The canonical smooth muscle cell marker TAGLN is present in endothelial cells and is involved in angiogenesis	29
Hypothesis-driven quantitative fluorescence microscopy – the importance of reverse-thinking in experimental design	29
In vivo imaging shows continued association of several IFT-A, IFT-B and dynein complexes while IFT trains U-turn at the tip	28
Ferroptosis induces membrane blebbing in placental trophoblasts	28
Accessory proteins of the zDHHC family of S-acylation enzymes	28
Regulation of hemidesmosome dynamics and cell signaling by integrin α6β4	27
Lipophagy at a glance	27
Evolution and insights into the structure and function of the DedA superfamily containing TMEM41B and VMP1	27
L-selectin regulates human neutrophil transendothelial migration	27
A three-organelle complex made by wrappER contacts with peroxisomes and mitochondria responds to liver lipid flux changes	27
Advances on the roles of tenascin-C in cancer	27
New insights into FAK structure and function in focal adhesions	27
On the asymmetric partitioning of nucleocytoplasmic transport – recent insights and open questions	26
A glucose-starvation response governs endocytic trafficking and eisosomal retention of surface cargoes in budding yeast	26
BCAT1 affects mitochondrial metabolism independently of leucine transamination in activated human macrophages	26
Centrosome maturation – in tune with the cell cycle	26
Spatial distribution of lamin A/C determines nuclear stiffness and stress-mediated deformation	26
Circulating prostate cancer cells have differential resistance to fluid shear stress-induced cell death	25
Luminescence lifetime imaging of three-dimensional biological objects	25
Cargo sorting at the trans-Golgi network at a glance	25
The journey of Ca2+ through the cell – pulsing through the network of ER membrane contact sites	25
The pleiotropic functions of autophagy in metastasis	25
Neutrophil transendothelial migration hotspots – mechanisms and implications	25
Aurora B and C kinases regulate chromosome desynapsis and segregation during mouse and human spermatogenesis	25
Molecular insight into how γ-TuRC makes microtubules	24
A piggybacking mechanism enables peroxisomal localization of the glyoxylate cycle enzyme Mdh2 in yeast	24
It takes two to tango – molecular links between plant immunity and brassinosteroid signalling	24

Insights into animal septins using recombinant human septin octamers with distinct SEPT9 isoforms	24
Palmitoylated CKAP4 regulates mitochondrial functions through an interaction with VDAC2 at ER–mitochondria contact sites	24
Ribosome quality control activity potentiates vaccinia virus protein synthesis during infection	23
Coordination of mitochondrial and cellular dynamics by the actin-based motor Myo19	23
IMC10 and LMF1 mediate mitochondrial morphology through mitochondrion–pellicle contact sites in Toxoplasma gondii	23
Phosphorylation of the AMPA receptor subunit GluA1 regulates clathrin-mediated receptor internalization	23
The Hob proteins are novel and conserved lipid-binding proteins at ER–PM contact sites	22
Mitochondrial dysfunction triggers a catabolic response in chondrocytes via ROS-mediated activation of the JNK/AP1 pathway	22
Malaria parasite egress at a glance	22
Visualising the cytoskeletal machinery in neuronal growth cones using cryo-electron tomography	22
Maintenance of complex I and its supercomplexes by NDUF-11 is essential for mitochondrial structure, function and health	22
Turgor-dependent and coronin-mediated F-actin dynamics drive septin disc-to-ring remodeling in the blast fungus Magnaporthe oryzae	22
Ribosome-associated quality control of membrane proteins at the endoplasmic reticulum	22
α-Arrestin ARRDC3 tumor suppressor function is linked to GPCR-induced TAZ activation and breast cancer metastasis	22
Forcing a growth factor response – tissue-stiffness modulation of integrin signaling and crosstalk with growth factor receptors	22
Diversity of mitophagy pathways at a glance	21
Dissecting lipid droplet biology with coherent Raman scattering microscopy	21
The tumor-suppressive long noncoding RNA DRAIC inhibits protein translation and induces autophagy by activating AMPK	21
Hydrostatic pressure prevents chondrocyte differentiation through heterochromatin remodeling	21
Combined heterogeneity in cell size and deformability promotes cancer invasiveness	21
Interaction between VPS13A and the XK scramblase is important for VPS13A function in humans	21
Depletion of a Toxoplasma porin leads to defects in mitochondrial morphology and contacts with the endoplasmic reticulum	21
Tubulin isotypes – functional insights from model organisms	21
Enhanced RhoA signalling stabilizes E-cadherin in migrating epithelial monolayers	21
Emerging functions of cytoskeletal proteins in immune diseases	21
The Bardet–Biedl syndrome complex component BBS1 controls T cell polarity during immune synapse assembly	21
Adenine nucleotide translocase regulates airway epithelial metabolism, surface hydration and ciliary function	20
Insight into the regulation of axonal transport from the study of KIF1A-associated neurological disorder	20
LRRC23 is a conserved component of the radial spoke that is necessary for sperm motility and male fertility in mice	20
The lysosomotrope GPN mobilises Ca2+ from acidic organelles	20
ApoE4 disrupts interaction of sortilin with fatty acid-binding protein 7 essential to promote lipid signaling	20
ULK1-mediated phosphorylation regulates the conserved role of YKT6 in autophagy	20
Dynamic remodeling of ribosomes and endoplasmic reticulum in axon terminals of motoneurons	20
The pivotal role of ERp44 in patrolling protein secretion	20
The p97–UBXN1 complex regulates aggresome formation	20
FAM209 associates with DPY19L2, and is required for sperm acrosome biogenesis and fertility in mice	20
Non-muscle myosin 2 at a glance	20
INPP5E controls ciliary localization of phospholipids and the odor response in olfactory sensory neurons	19
Blockage of bone morphogenetic protein signalling counteracts hypertrophy in a human osteoarthritic micro-cartilage model	19
Trio family proteins as regulators of cell migration and morphogenesis in development and disease – mechanisms and cellular contexts	19
Importin-9 regulates chromosome segregation and packaging in Drosophila germ cells	19
Lamellipodia-like actin networks in cells lacking WAVE regulatory complex	19
A lamin A/C variant causing striated muscle disease provides insights into filament organization	19
YAP, CTGF and Cyr61 are overexpressed in tamoxifen-resistant breast cancer and induce transcriptional repression of ERα	19
Mechanical and chemical activation of GPR68 probed with a genetically encoded fluorescent reporter	19
Exploring cell and tissue mechanics with optical tweezers	19
Cargo adapters expand the transport range of intraflagellar transport	19
Cellular metabolism in the defense against microbes	19
TRP channels in health and disease at a glance	19
A general role for TANGO1, encoded by MIA3, in secretory pathway organization and function	19
Rab5 regulates macropinocytosis by recruiting the inositol 5-phosphatases OCRL and Inpp5b that hydrolyse PtdIns(4,5)P2	18
Shedding of ciliary vesicles at a glance	18
The yeast FIT2 homologs are necessary to maintain cellular proteostasis and membrane lipid homeostasis	18
Emerin regulation of nuclear stiffness is required for fast amoeboid migration in confined environments	18
Direct evidence of cellular transformation by prion-like p53 amyloid infection	18
Isoform-dependent lysosomal degradation and internalization of apolipoprotein E requires autophagy proteins	18
The role of icIL-1RA in keratinocyte senescence and development of the senescence-associated secretory phenotype	18
Large organellar changes occur during mild heat shock in yeast	18
Differential cellular responses to adhesive interactions with galectin-8- and fibronectin-coated substrates	18
Identification of a heat-inducible novel nuclear body containing the long noncoding RNA MALAT1	18
A novel function for Rab1 and Rab11 during secretory granule maturation	18
Innate immune receptor clustering and its role in immune regulation	18
The prophase oocyte nucleus is a homeostatic G-actin buffer	18
The synthetic TRPML1 agonist ML-SA1 rescues Alzheimer-related alterations of the endosomal-autophagic-lysosomal system	18
An optogenetic method for interrogating YAP1 and TAZ nuclear–cytoplasmic shuttling	17
Ca2+ elevations disrupt interactions between intraflagellar transport and the flagella membrane in Chlamydomonas	17
S-acylation of Orai1 regulates store-operated Ca2+ entry	17
Tyrosine kinase-independent actions of DDR2 in tumor cells and cancer-associated fibroblasts influence tumor invasion, migration and metastasis	17
WNK1 is a chloride-stimulated scaffold that regulates mTORC2 activity and ion transport	17
ADAR1 limits stress granule formation through both translation-dependent and translation-independent mechanisms	17
Chick cranial neural crest cells release extracellular vesicles that are critical for their migration	17
Near-infrared imaging in fission yeast using a genetically encoded phycocyanobilin biosynthesis system	17
Interplay between myofibers and pro-inflammatory macrophages controls muscle damage in mdx mice	17
Emerging insights into serine/threonine-specific phosphoprotein phosphatase function and selectivity	17
Cytoskeletal mechanics and dynamics in the Drosophila syncytial embryo	17
Ultrastructure expansion microscopy reveals the cellular architecture of budding and fission yeast	17
Fibroblastic reticular cell response to dendritic cells requires coordinated activity of podoplanin, CD44 and CD9	17
Data science in cell imaging	17
Polarisome assembly mediates actin remodeling during polarized yeast and fungal growth	17
SMARCA2 is regulated by NORFA–miR-29c, a novel pathway that controls granulosa cell apoptosis and is related to female fertility	17

Genetic compensation for cilia defects in cep290 mutants by upregulation of cilia-associated small GTPases	17
Desmosome dualism – most of the junction is stable, but a plakophilin moiety is persistently dynamic	17
Hit the brakes – a new perspective on the loop extrusion mechanism of cohesin and other SMC complexes	17
Cytoplasmic factories for axonemal dynein assembly	17
The role of nuclear Ca2+ in maintaining neuronal homeostasis and brain health	17
Rab7b regulates dendritic cell migration by linking lysosomes to the actomyosin cytoskeleton	17
Myo19 tethers mitochondria to endoplasmic reticulum-associated actin to promote mitochondrial fission	17
Roles of the actin cytoskeleton in ciliogenesis	17
Coupling of dynamic microtubules to F-actin by Fmn2 regulates chemotaxis of neuronal growth cones	16
Selective axonal translation of the mRNA isoform encoding prenylated Cdc42 supports axon growth	16
Intercellular and intracellular cilia orientation is coordinated by CELSR1 and CAMSAP3 in oviduct multi-ciliated cells	16
TORC1 and PKA activity towards ribosome biogenesis oscillates in synchrony with the budding yeast cell cycle	16
Bacteria- and host-derived extracellular vesicles – two sides of the same coin?	16
The role of mitochondrial dynamics in mtDNA maintenance	16
Centrosome maturation requires phosphorylation-mediated sequential domain interactions of SPD-5	16
The actin cytoskeleton-MRTF/SRF cascade transduces cellular physical niche cues to entrain the circadian clock	16
Structural model of human PORCN illuminates disease-associated variants and drug-binding sites	16
Response of cells and tissues to shear stress	16
α-Actinin-4 drives invasiveness by regulating myosin IIB expression and myosin IIA localization	16
Supply chain logistics – the role of the Golgi complex in extracellular matrix production and maintenance	16
Picornavirus 3C – a protease ensuring virus replication and subverting host responses	16
Expression analysis and function of mitochondrial genome-encoded microRNAs	15
Ana1 helps recruit Polo to centrioles to promote mitotic PCM assembly and centriole elongation	15
Non-canonical argonaute loading of extracellular vesicle-derived exogenous single-stranded miRNA in recipient cells	15
The surface of lipid droplets constitutes a barrier for endoplasmic reticulum-resident integral membrane proteins	15
Chlamydomonas FAP70 is a component of the previously uncharacterized ciliary central apparatus projection C2a	15
A dual role of YAP in driving TGFβ-mediated endothelial-to-mesenchymal transition	15
Stable tug-of-war between kinesin-1 and cytoplasmic dynein upon different ATP and roadblock concentrations	15
Concurrent depletion of Vps37 proteins evokes ESCRT-I destabilization and profound cellular stress responses	15
De novo formation of early endosomes during Rab5-to-Rab7a transition	15
MyomiRs and their multifaceted regulatory roles in muscle homeostasis and amyotrophic lateral sclerosis	15
Fibronectin Extra Domains tune cellular responses and confer topographically distinct features to fibril networks	15
Dynein at the kinetochore	15
Diverse mechanisms regulate contractile ring assembly for cytokinesis in the two-cell Caenorhabditis elegans embryo	15
Decoupling SARS-CoV-2 ORF6 localization and interferon antagonism	15
The role of lipid rafts in vesicle formation	15
MITOL-mediated DRP1 ubiquitylation and degradation promotes mitochondrial hyperfusion in a CMT2A-linked MFN2 mutant	15
Aggrephagy at a glance	14
Shaping centromeres to resist mitotic spindle forces	14
Metformin inactivates the cGAS-STING pathway through autophagy and suppresses senescence in nucleus pulposus cells	14
Hijacking of the host cell Golgi by Plasmodium berghei liver stage parasites	14
Diacylglycerol at the inner nuclear membrane fuels nuclear envelope expansion in closed mitosis	14
Nuclear localization of p65 reverses therapy-induced senescence	14
Managing risky assets – mitophagy in vivo	14
DNAJB chaperones suppress destabilised protein aggregation via a region distinct from that used to inhibit amyloidogenesis	14
Septin-microtubule association via a motif unique to isoform 1 of septin 9 tunes stress fibers	14
Lipid droplets form a network interconnected by the endoplasmic reticulum through which their proteins equilibrate	14
Co-transport of the nuclear-encoded Cox7c mRNA with mitochondria along axons occurs through a coding-region-dependent mechanism	14
Mitochondrial Ca2+ uniporter haploinsufficiency enhances long-term potentiation at hippocampal mossy fibre synapses	14
Emerging evidence for kindlin oligomerization and its role in regulating kindlin function	14
Single-cell intracellular pH dynamics regulate the cell cycle by timing the G1 exit and G2 transition	14
Intracellular flow cytometric lipid analysis – a multiparametric system to assess distinct lipid classes in live cells	14
Stress-induced phase separation of ERES components into Sec bodies precedes ER exit inhibition in mammalian cells	14
EVI/WLS function is regulated by ubiquitylation and is linked to ER-associated degradation by ERLIN2	14
Selective microautophagy of proteasomes is initiated by ESCRT-0 and is promoted by proteasome ubiquitylation	14
Single-cell imaging of ERK and Akt activation dynamics and heterogeneity induced by G-protein-coupled receptors	14
DRP1 mutations associated with EMPF1 encephalopathy alter mitochondrial membrane potential and metabolic programs	14
Local translation in perisynaptic and perivascular astrocytic processes – a means to ensure astrocyte molecular and functional polarity?	14
Go with the flow – bulk transport by molecular motors	14
When light meets biology – how the specimen affects quantitative microscopy	14
Identification of mutants with increased variation in cell size at onset of mitosis in fission yeast	14
Reciprocal regulation of p21 and Chk1 controls the cyclin D1-RB pathway to mediate senescence onset after G2 arrest	13
Conserved cholesterol-related activities of Dispatched 1 drive Sonic hedgehog shedding from the cell membrane	13
Ssc-miR-21-5p regulates endometrial epithelial cell proliferation, apoptosis and migration via the PDCD4/AKT pathway	13
SAF-A promotes origin licensing and replication fork progression to ensure robust DNA replication	13
Genome-wide imaging screen uncovers molecular determinants of arsenite-induced protein aggregation and toxicity	13
Mechanical role of the submembrane spectrin scaffold in red blood cells and neurons	13
PEX11β and FIS1 cooperate in peroxisome division independently of mitochondrial fission factor	13
Choreographing the motor-driven endosomal dance	13
Cell-to-cell and genome-to-genome variability of adenovirus transcription tuned by the cell cycle	13
Smaug1 membrane-less organelles respond to AMPK and mTOR and affect mitochondrial function	13
Oncogenic gain of function due to p53 amyloids occurs through aberrant alteration of cell cycle and proliferation	13
Organization and dynamics of the cortical complexes controlling insulin secretion in β-cells	13
Glucocorticoids enhance chemotherapy-driven stress granule assembly and impair granule dynamics, leading to cell death	13
Mechanosensitive expression of lamellipodin promotes intracellular stiffness, cyclin expression and cell proliferation	13
AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer	13
Distinct myofibre domains of the human myotendinous junction revealed by single-nucleus RNA sequencing	13
Dissecting the PRSS37 interactome and potential mechanisms leading to ADAM3 loss in PRSS37-null sperm	13
Ubiquitin-assisted phase separation of dishevelled-2 promotes Wnt signalling	13
ESCRT recruitment by the S. cerevisiae inner nuclear membrane protein Heh1 is regulated by Hub1-mediated alternative splicing	13
Lysosomal TRPML1 regulates mitochondrial function in hepatocellular carcinoma cells	13
Trophoblast organoids with physiological polarity model placental structure and function	13
A new mechanism of fibronectin fibril assembly revealed by live imaging and super-resolution microscopy	13
Prion protein and prion disease at a glance	13
The physiology, pathology and potential therapeutic application of serotonylation	13
Tumour-directed microenvironment remodelling at a glance	12
Kif9 is an active kinesin motor required for ciliary beating and proximodistal patterning of motile axonemes	12
N1-acetylspermidine is a determinant of hair follicle stem cell fate	12
A quantitative study of the Golgi retention of glycosyltransferases	12
Coupled protein quality control during nonsense-mediated mRNA decay	12
Establishment and analysis of conditional Rab1- and Rab5-knockout cells using the auxin-inducible degron system	12
An interpretable and versatile machine learning approach for oocyte phenotyping	12
Spatial constraints on chromosomes are instrumental to meiotic pairing	12
An autophagy-dependent tubular lysosomal network synchronizes degradative activity required for muscle remodeling	12
Comparative analysis of vertebrates reveals that mouse primordial oocytes do not contain a Balbiani body	12