Journal of Cell Biology

Papers
(The TQCC of Journal of Cell Biology is 17. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-06-01 to 2024-06-01.)
ArticleCitations
LNCcation: lncRNA localization and function670
Mitochondrial regulation of ferroptosis218
Lysosome biogenesis: Regulation and functions179
The cell biology of synapse formation161
Paradoxical roles of caspase-3 in regulating cell survival, proliferation, and tumorigenesis129
Mitophagy pathways in health and disease123
Critical role of mitochondrial ubiquitination and the OPTN–ATG9A axis in mitophagy112
Liquid–liquid phase separation in autophagy104
SARM1 acts downstream of neuroinflammatory and necroptotic signaling to induce axon degeneration103
TMEM41B and VMP1 are scramblases and regulate the distribution of cholesterol and phosphatidylserine99
STING induces LC3B lipidation onto single-membrane vesicles via the V-ATPase and ATG16L1-WD40 domain96
Cancer cells educate natural killer cells to a metastasis-promoting cell state92
FUS-dependent liquid–liquid phase separation is important for DNA repair initiation91
Lipid droplets in the nervous system91
VPS13D bridges the ER to mitochondria and peroxisomes via Miro90
The RNA binding protein FMR1 controls selective exosomal miRNA cargo loading during inflammation89
Mechanisms of nonvesicular lipid transport88
The NLRP3–inflammasome as a sensor of organelle dysfunction84
The cell biology of Parkinson’s disease81
Recognition of RNA by the S9.6 antibody creates pervasive artifacts when imaging RNA:DNA hybrids78
Who’s in control? Principles of Rab GTPase activation in endolysosomal membrane trafficking and beyond75
CDK4/6 regulate lysosome biogenesis through TFEB/TFE371
Sequential dynein effectors regulate axonal autophagosome motility in a maturation-dependent pathway71
3D FIB-SEM reconstruction of microtubule–organelle interaction in whole primary mouse β cells68
The proline-rich domain promotes Tau liquid–liquid phase separation in cells64
Endosomal escape of delivered mRNA from endosomal recycling tubules visualized at the nanoscale63
Phospholipid ebb and flow makes mitochondria go63
COPII collar defines the boundary between ER and ER exit site and does not coat cargo containers63
Similarities and interplay between senescent cells and macrophages62
Pathogenic mutations in the kinesin-3 motor KIF1A diminish force generation and movement through allosteric mechanisms62
Secretory autophagy maintains proteostasis upon lysosome inhibition60
Phase separation of Axin organizes the β-catenin destruction complex59
V-ATPase is a universal regulator of LC3-associated phagocytosis and non-canonical autophagy59
High-fidelity reconstitution of stress granules and nucleoli in mammalian cellular lysate58
Evolving models for assembling and shaping clathrin-coated pits58
ULK complex organization in autophagy by a C-shaped FIP200 N-terminal domain dimer58
ECM deposition is driven by caveolin-1–dependent regulation of exosomal biogenesis and cargo sorting56
High-content imaging-based pooled CRISPR screens in mammalian cells55
Time-resolved proteomics profiling of the ciliary Hedgehog response54
Ubiquitin chains earmark GPCRs for BBSome-mediated removal from cilia53
The long journey to bring a Myc inhibitor to the clinic53
PINK1 drives production of mtDNA-containing extracellular vesicles to promote invasiveness53
Topological features of integrin adhesion complexes revealed by multiplexed proximity biotinylation52
Nuclear lipid droplets form in the inner nuclear membrane in a seipin-independent manner51
Image-based pooled whole-genome CRISPRi screening for subcellular phenotypes50
Role of the early secretory pathway in SARS-CoV-2 infection50
VPS13D promotes peroxisome biogenesis50
Transmembrane phospholipid translocation mediated by Atg9 is involved in autophagosome formation48
Polo-like kinase 1 independently controls microtubule-nucleating capacity and size of the centrosome46
Adherens junction regulates cryptic lamellipodia formation for epithelial cell migration44
Catalytically inactive, purified RNase H1: A specific and sensitive probe for RNA–DNA hybrid imaging44
Coupling of translation quality control and mRNA targeting to stress granules43
Sarm1 activation produces cADPR to increase intra-axonal Ca++ and promote axon degeneration in PIPN43
Protrudin-mediated ER–endosome contact sites promote MT1-MMP exocytosis and cell invasion43
Binding and transport of SFPQ-RNA granules by KIF5A/KLC1 motors promotes axon survival42
CDC42EP5/BORG3 modulates SEPT9 to promote actomyosin function, migration, and invasion42
Regulation of Golgi turnover by CALCOCO1-mediated selective autophagy41
Phagosome resolution regenerates lysosomes and maintains the degradative capacity in phagocytes41
Direct binding of ESCRT protein Chm7 to phosphatidic acid–rich membranes at nuclear envelope herniations41
High-speed single-molecule imaging reveals signal transduction by induced transbilayer raft phases40
Interferon-stimulated gene 15 accelerates replication fork progression inducing chromosomal breakage40
ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling39
mTORC1 activity is supported by spatial association with focal adhesions39
Computational analyses reveal spatial relationships between nuclear pore complexes and specific lamins39
Synaptic activity controls autophagic vacuole motility and function in dendrites39
SAMM50 acts with p62 in piecemeal basal- and OXPHOS-induced mitophagy of SAM and MICOS components39
Mechanosensitive calcium flashes promote sustained RhoA activation during tight junction remodeling38
FIT2 is an acyl–coenzyme A diphosphatase crucial for endoplasmic reticulum homeostasis38
ER as master regulator of membrane trafficking and organelle function38
Rapid degradation of GRASP55 and GRASP65 reveals their immediate impact on the Golgi structure38
Structural and biochemical insights into lipid transport by VPS13 proteins38
DOT1L modulates the senescence-associated secretory phenotype through epigenetic regulation of IL1A37
Tyramide signal amplification mass spectrometry (TSA-MS) ratio identifies nuclear speckle proteins37
Caveolin-1 and cavin1 act synergistically to generate a unique lipid environment in caveolae37
Quantitative correlative microscopy reveals the ultrastructural distribution of endogenous endosomal proteins36
NCOA4 drives ferritin phase separation to facilitate macroferritinophagy and microferritinophagy36
Analysis of copy number alterations reveals the lncRNA ALAL-1 as a regulator of lung cancer immune evasion36
PI4P/PS countertransport by ORP10 at ER–endosome membrane contact sites regulates endosome fission35
High-precision targeting workflow for volume electron microscopy35
A cryo-ET survey of microtubules and intracellular compartments in mammalian axons35
The WAVE complex associates with sites of saddle membrane curvature35
The modified mitochondrial outer membrane carrier MTCH2 links mitochondrial fusion to lipogenesis35
HDAC6 regulates microtubule stability and clustering of AChRs at neuromuscular junctions35
Ubiquitin ligase MARCH5 localizes to peroxisomes to regulate pexophagy35
XMAP215 promotes microtubule catastrophe by disrupting the growing microtubule end34
Nesprins are mechanotransducers that discriminate epithelial–mesenchymal transition programs33
GOLPH3 and GOLPH3L are broad-spectrum COPI adaptors for sorting into intra-Golgi transport vesicles33
Angulin-1 seals tricellular contacts independently of tricellulin and claudins33
Telomerase treatment prevents lung profibrotic pathologies associated with physiological aging33
Lipid droplets and the host–pathogen dynamic: FATal attraction?33
The cell biology of inflammation: From common traits to remarkable immunological adaptations33
MICAL2 enhances branched actin network disassembly by oxidizing Arp3B-containing Arp2/3 complexes33
Label-retention expansion microscopy33
The Rab7 effector WDR91 promotes autophagy-lysosome degradation in neurons by regulating lysosome fusion33
Intracellular wetting mediates contacts between liquid compartments and membrane-bound organelles33
FHL2 anchors mitochondria to actin and adapts mitochondrial dynamics to glucose supply32
Optogenetic activators of apoptosis, necroptosis, and pyroptosis32
USP19 promotes hypoxia-induced mitochondrial division via FUNDC1 at ER-mitochondria contact sites32
Cnm1 mediates nucleus–mitochondria contact site formation in response to phospholipid levels32
A guide to membrane atg8ylation and autophagy with reflections on immunity32
Long-lived mitochondrial cristae proteins in mouse heart and brain32
A non-canonical Hedgehog pathway initiates ciliogenesis and autophagy32
Alternative splicing of clathrin heavy chain contributes to the switch from coated pits to plaques32
PLCγ1 promotes phase separation of T cell signaling components31
Phosphorylation of SNX27 by MAPK11/14 links cellular stress–signaling pathways with endocytic recycling31
In situ cryo-electron tomography reveals filamentous actin within the microtubule lumen31
ER–mitochondria contacts promote mitochondrial-derived compartment biogenesis31
NBR1: The archetypal selective autophagy receptor31
Capture and delivery of tail-anchored proteins to the endoplasmic reticulum31
ANO5 ensures trafficking of annexins in wounded myofibers30
Specific KIF1A–adaptor interactions control selective cargo recognition30
CRISPR screens for lipid regulators reveal a role for ER-bound SNX13 in lysosomal cholesterol export30
A mitochondrial contribution to anti-inflammatory shear stress signaling in vascular endothelial cells30
Opposing functions for retromer and Rab11 in extracellular vesicle traffic at presynaptic terminals30
Vps13-like proteins provide phosphatidylethanolamine for GPI anchor synthesis in the ER30
Kinetochore-bound Mps1 regulates kinetochore–microtubule attachments via Ndc80 phosphorylation30
MICOS subcomplexes assemble independently on the mitochondrial inner membrane in proximity to ER contact sites30
Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination29
Atg39 links and deforms the outer and inner nuclear membranes in selective autophagy of the nucleus29
GTP-dependent formation of straight tubulin oligomers leads to microtubule nucleation29
CENP-A overexpression promotes aneuploidy with karyotypic heterogeneity29
mRNA localization mediates maturation of cytoplasmic cilia in Drosophila spermatogenesis29
ORP5 and ORP8 orchestrate lipid droplet biogenesis and maintenance at ER–mitochondria contact sites29
Notch2 complements Notch1 to mediate inductive signaling that initiates early T cell development29
Plectin-mediated cytoskeletal crosstalk controls cell tension and cohesion in epithelial sheets29
Subcellular localization of the J-protein Sis1 regulates the heat shock response29
Branched actin networks are assembled on microtubules by adenomatous polyposis coli for targeted membrane protrusion29
Deorphanizing FAM19A proteins as pan-neurexin ligands with an unusual biosynthetic binding mechanism28
A polybasic domain in aPKC mediates Par6-dependent control of membrane targeting and kinase activity28
Liquid–liquid phase separation facilitates the biogenesis of secretory storage granules28
Dendritic cell actin dynamics control contact duration and priming efficiency at the immunological synapse28
MyD88 oligomer size functions as a physical threshold to trigger IL1R Myddosome signaling28
C-ferroptosis is an iron-dependent form of regulated cell death in cyanobacteria28
Induction of spontaneous human neocentromere formation and long-term maturation28
The UPRmt preserves mitochondrial import to extend lifespan28
WASP integrates substrate topology and cell polarity to guide neutrophil migration28
Kinetochore phosphatases suppress autonomous Polo-like kinase 1 activity to control the mitotic checkpoint28
Centriole-independent mitotic spindle assembly relies on the PCNT–CDK5RAP2 pericentriolar matrix28
A septin GTPase scaffold of dynein–dynactin motors triggers retrograde lysosome transport27
p53 deficiency triggers dysregulation of diverse cellular processes in physiological oxygen27
Atlastin 2/3 regulate ER targeting of the ULK1 complex to initiate autophagy27
Evidence for anaphase pulling forces during C. elegans meiosis27
Vps13D functions in a Pink1-dependent and Parkin-independent mitophagy pathway27
A ciliopathy complex builds distal appendages to initiate ciliogenesis27
Cell division requires RNA eviction from condensing chromosomes27
Twinfilin bypasses assembly conditions and actin filament aging to drive barbed end depolymerization26
ATG9 vesicles comprise the seed membrane of mammalian autophagosomes26
An antibody toolbox to track complex I assembly defines AIF’s mitochondrial function26
NUCKS1 promotes RAD54 activity in homologous recombination DNA repair26
TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination26
The ER cholesterol sensor SCAP promotes CARTS biogenesis at ER–Golgi membrane contact sites26
Neuronal endolysosomal transport and lysosomal functionality in maintaining axonostasis26
Regulating peroxisome–ER contacts via the ACBD5-VAPB tether by FFAT motif phosphorylation and GSK3β26
Biochemical reconstitutions reveal principles of human γ-TuRC assembly and function26
CDKD-dependent activation of CDKA;1 controls microtubule dynamics and cytokinesis during meiosis25
STING controls energy stress-induced autophagy and energy metabolism via STX1725
Consensus nomenclature for dyneins and associated assembly factors25
Live imaging of transcription sites using an elongating RNA polymerase II–specific probe25
Cell migration orchestrates migrasome formation by shaping retraction fibers25
Effector-mediated ERM activation locally inhibits RhoA activity to shape the apical cell domain25
Conserved actin machinery drives microtubule-independent motility and phagocytosis in Naegleria25
VMP1 and TMEM41B are essential for DMV formation during β-coronavirus infection25
Quantitative analysis of autophagy reveals the role of ATG9 and ATG2 in autophagosome formation24
Nucleobindin-1 regulates ECM degradation by promoting intra-Golgi trafficking of MMPs24
Retinyl esters form lipid droplets independently of triacylglycerol and seipin24
FIT2 organizes lipid droplet biogenesis with ER tubule-forming proteins and septins24
Mitochondrial dysfunction compromises ciliary homeostasis in astrocytes24
LUZP1 and the tumor suppressor EPLIN modulate actin stability to restrict primary cilia formation24
Shared and specific functions of Arfs 1–5 at the Golgi revealed by systematic knockouts24
Stochastic combinations of actin regulatory proteins are sufficient to drive filopodia formation24
Myelination generates aberrant ultrastructure that is resolved by microglia24
Teasing out function from morphology: Similarities between primary cilia and immune synapses24
Plk4 triggers autonomous de novo centriole biogenesis and maturation24
JIP3 interacts with dynein and kinesin-1 to regulate bidirectional organelle transport24
SARS-CoV-2 ORF10 impairs cilia by enhancing CUL2ZYG11B activity24
The +TIP Navigator-1 is an actin–microtubule crosslinker that regulates axonal growth cone motility24
Genetically encoded live-cell sensor for tyrosinated microtubules24
Nano-scale resolution of native retinal rod disk membranes reveals differences in lipid composition24
E3 ubiquitin ligase Wwp1 regulates ciliary dynamics of the Hedgehog receptor Smoothened24
Tension promotes kinetochore–microtubule release by Aurora B kinase23
Stable inheritance of CENP-A chromatin: Inner strength versus dynamic control23
ER membrane contact sites support endosomal small GTPase conversion for exosome secretion23
Dual spindles assemble in bovine zygotes despite the presence of paternal centrosomes23
Collective invasion induced by an autocrine purinergic loop through connexin-43 hemichannels23
The cell biology of fertilization: Gamete attachment and fusion23
Autophagy facilitates mitochondrial rebuilding after acute heat stress via a DRP-1–dependent process23
Regulation of membrane NMDA receptors by dynamics and protein interactions23
Object detection networks and augmented reality for cellular detection in fluorescence microscopy23
Tricellulin secures the epithelial barrier at tricellular junctions by interacting with actomyosin23
Quality control of 40S ribosome head assembly ensures scanning competence23
Stress granules and mTOR are regulated by membrane atg8ylation during lysosomal damage23
ZNF416 is a pivotal transcriptional regulator of fibroblast mechanoactivation22
Combinatorial multivalent interactions drive cooperative assembly of the COPII coat22
Mechanical competition alters the cellular interpretation of an endogenous genetic program22
A loop extrusion–independent mechanism contributes to condensin I–mediated chromosome shaping22
An APEX2 proximity ligation method for mapping interactions with the nuclear lamina22
An asymmetric junctional mechanoresponse coordinates mitotic rounding with epithelial integrity22
WDR60-mediated dynein-2 loading into cilia powers retrograde IFT and transition zone crossing22
Extracellular vesicles from neurons promote neural induction of stem cells through cyclin D122
Phase separation and toxicity of C9orf72 poly(PR) depends on alternate distribution of arginine22
The function of GORASPs in Golgi apparatus organization in vivo21
ESCRT, not intralumenal fragments, sorts ubiquitinated vacuole membrane proteins for degradation21
A versatile cortical pattern-forming circuit based on Rho, F-actin, Ect2, and RGA-3/421
Fyn and TOM1L1 are recruited to clathrin-coated pits and regulate Akt signaling21
Karyopherin enrichment and compensation fortifies the nuclear pore complex against nucleocytoplasmic leakage21
Centriole and PCM cooperatively recruit CEP192 to spindle poles to promote bipolar spindle assembly21
c entrocortin RNA localization to centrosomes is regulated by FMRP and facilitates error-free mitosis21
Mitochondria on the move: Horizontal mitochondrial transfer in disease and health21
Per1/Per2–Igf2 axis–mediated circadian regulation of myogenic differentiation21
Zc3h10 regulates adipogenesis by controlling translation and F-actin/mitochondria interaction21
Intersection of TKS5 and FGD1/CDC42 signaling cascades directs the formation of invadopodia21
Stress-responsive regulation of extracellular proteostasis21
Anisotropic expansion of hepatocyte lumina enforced by apical bulkheads20
Sterol and oxysterol synthases near the ciliary base activate the Hedgehog pathway20
Lymphocyte egress signal sphingosine-1-phosphate promotes ERM-guided, bleb-based migration20
Inhibition of class I PI3K enhances chaperone-mediated autophagy20
The deubiquitylase USP9X controls ribosomal stalling20
O-GlcNAc modification of nuclear pore complexes accelerates bidirectional transport20
Signaling by the integrated stress response kinase PKR is fine-tuned by dynamic clustering20
Myeloid-derived growth factor regulates neutrophil motility in interstitial tissue damage20
Superresolution characterization of core centriole architecture20
Aurora A kinase activation: Different means to different ends20
CYRI-A limits invasive migration through macropinosome formation and integrin uptake regulation20
Quality assessment in light microscopy for routine use through simple tools and robust metrics20
Pex30-like proteins function as adaptors at distinct ER membrane contact sites20
Reduced insulin/IGF1 signaling prevents immune aging via ZIP-10/bZIP–mediated feedforward loop20
Mechanosensitive collaboration between integrins and connexins allows nutrient and antioxidant transport into the lens20
Mechanism of p38 MAPK–induced EGFR endocytosis and its crosstalk with ligand-induced pathways20
The HSPG syndecan is a core organizer of cholinergic synapses20
A conserved myotubularin-related phosphatase regulates autophagy by maintaining autophagic flux20
Multivalent interactions make adherens junction–cytoskeletal linkage robust during morphogenesis20
Novel phospho-switch function of delta-catenin in dendrite development20
Centromeric transcription maintains centromeric cohesion in human cells20
Composition and organization of kinetochores show plasticity in apicomplexan chromosome segregation20
Detection and quantification of the vacuolar H+ATPase using the Legionella effector protein SidK20
Lysine acetylation of cytoskeletal proteins: Emergence of an actin code19
EGFR-mediated epidermal stem cell motility drives skin regeneration through COL17A1 proteolysis19
The LTB4–BLT1 axis regulates actomyosin and β2-integrin dynamics during neutrophil extravasation19
In situ cryo-electron tomography reveals local cellular machineries for axon branch development19
DNA damage promotes microtubule dynamics through a DNA-PK-AKT axis for enhanced repair19
Chromosome compartmentalization alterations in prostate cancer cell lines model disease progression19
Filament organization of the bacterial actin MreB is dependent on the nucleotide state19
Leep1 interacts with PIP3 and the Scar/WAVE complex to regulate cell migration and macropinocytosis19
EGFR-RAS-MAPK signaling is confined to the plasma membrane and associated endorecycling protrusions19
Chromosome oscillation promotes Aurora A–dependent Hec1 phosphorylation and mitotic fidelity19
High-throughput single-cell epigenomic profiling by targeted insertion of promoters (TIP-seq)19
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality19
Cavin4 interacts with Bin1 to promote T-tubule formation and stability in developing skeletal muscle19
Cdc42 GTPase regulates ESCRTs in nuclear envelope sealing and ER remodeling19
Poly(ADP-ribose) binding and macroH2A mediate recruitment and functions of KDM5A at DNA lesions19
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