Journal of Cell Biology

Article	Citations
PP6 regulation of Aurora A–TPX2 limits NDC80 phosphorylation and mitotic spindle size	354
LUBAC regulates ciliogenesis by promoting CP110 removal from the mother centriole	146
Vps13-like proteins provide phosphatidylethanolamine for GPI anchor synthesis in the ER	137
Stress granules and mTOR are regulated by membrane atg8ylation during lysosomal damage	125
A conserved role for centriolar satellites in translation of centrosomal and ciliary proteins	96
Microtubule-driven cell shape changes and actomyosin flow synergize to position the centrosome	83
Lipid droplets: Open questions and conceptual advances around a unique organelle	82
Kinetochores grip microtubules with directionally asymmetric strength	80
The PAX3-FOXO1 fusion gene reduces cell–ECM interactions and TGFβ signaling in rhabdomyosarcoma	79
DBF4, not DRF1, is the crucial regulator of CDC7 kinase at replication forks	73
Tubulin isotypes optimize distinct spindle positioning mechanisms during yeast mitosis	73
Conformational transitions of the Spindly adaptor underlie its interaction with Dynein and Dynactin	72
Sugar-free synapses run on mitochondrial Sirtuin 3	71
RIM and MUNC13 membrane–binding domains are essential for neuropeptide secretion	69
Distinct roles of two homologous kinesins in mammalian motile cilia	67
Developmental pruning of sensory neurites by mechanical tearing in Drosophila	66
VPS13B is localized at the interface between Golgi cisternae and is a functional partner of FAM177A1	66
A collective strategy to promote the dissemination of single cancer cells	66
ESCRT-I and PTPN23 mediate microautophagy of ubiquitylated tau aggregates	64
Mechanisms of genome instability from cellular folate stress	63
Differential metabolism of arsenicals regulates Fps1-mediated arsenite transport	62
GxcM-Fbp17/RacC-WASP signaling regulates polarized cortex assembly in migrating cells via Arp2/3	62
A function of TPL/TBL1-type corepressors is to nucleate the assembly of the preinitiation complex	62
The α-Catenin mechanosensing M region is required for cell adhesion during tissue morphogenesis	61
Reticulons promote formation of ER-derived double-membrane vesicles that facilitate SARS-CoV-2 replication	61

Diverse microtubule-binding repeats regulate TPX2 activities at distinct locations within the spindle	61
Tld1 is a regulator of triglyceride lipolysis that demarcates a lipid droplet subpopulation	59
A gene duplication of a septin reveals a developmentally regulated filament length control mechanism	58
SARS-CoV-2 specific adaptations in N protein inhibit NF-κB activation and alter pathogenesis	57
C17orf80 binds the mitochondrial genome to promote its replication	57
Organization of a cytoskeletal superstructure in the apical domain of intestinal tuft cells	56
PtdIns(3,4)P2, Lamellipodin, and VASP coordinate actin dynamics during phagocytosis in macrophages	55
Rab GTPases as “eat me” signals for selective autophagy	55
Bill Weis (1959–2023): Pioneering structural biologist and biochemist who revolutionized our understanding of cell adhesion and Wnt signaling	54
Stu2 performs an essential kinetochore function independent of its microtubule polymerase activity	51
Taperin bundles F-actin at stereocilia pivot points enabling optimal lifelong mechanosensitivity	51
Astral microtubule cross-linking safeguards uniform nuclear distribution in the Drosophila syncytium	51
Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking	51
The phospholipids cardiolipin and phosphatidylethanolamine differentially regulate MDC biogenesis	49
Cryo-EM reveals how the mastigoneme assembles and responds to environmental signal changes	49
Refining S-acylation: Structure, regulation, dynamics, and therapeutic implications	48
Centriole structural integrity defects are a crucial feature of hydrolethalus syndrome	47
Phollow the phosphoinositol: Actin dynamics at the B cell immune synapse	47
Mechanisms of nuclear segregation in a multinucleate multibudding yeast	47
Crosstalk within and beyond the Polycomb repressive system	46
Allocation of resources among multiple daughter cells	45
FGFR2 residence in primary cilia is necessary for epithelial cell signaling	45
PD-LI promotes rear retraction during persistent cell migration by altering integrin β4 dynamics	43
Migrasomes: Biogenesis, physiological roles, and therapeutic potentials	42
ARHGEF17/TEM4 regulates the cell cycle through control of G1 progression	42
Tubulin regulates stability and localization of STMN2 by binding preferentially to its soluble form	42
Migratory autolysosome disposal mitigates lysosome damage	42
Newborn daughters get a fresh start through PI(3,5)P2-mediated vacuolar acidification	41
TIMP-1 is a novel ligand of Amyloid Precursor Protein and triggers a proinflammatory phenotype in human monocytes	41
Liquid–liquid phase separation facilitates the biogenesis of secretory storage granules	41
Competition for calnexin binding regulates secretion and turnover of misfolded GPI-anchored proteins	40
Human atlastin-3 is a constitutive ER membrane fusion catalyst	40
New editorial board members	39
A complex of the lipid transport ER proteins TMEM24 and C2CD2 with band 4.1 at cell–cell contacts	39
Microtubule-binding domains in Katanin p80 subunit are essential for severing activity inC. elegans	39
A biotin-HaloTag ligand enables efficient affinity capture of protein variants from live cells	38
Paxillin phase separation promotes focal adhesion assembly and integrin signaling	38
Induced nanoscale membrane curvature bypasses the essential endocytic function of clathrin	37
In situ cryo-electron tomography reveals local cellular machineries for axon branch development	36
Eps15/Pan1p is a master regulator of the late stages of the endocytic pathway	36
DeepContact: High-throughput quantification of membrane contact sites based on electron microscopy imaging	35
Genome-wide conditional degron libraries for functional genomics	35
Spatially coordinated cell cycle activity and motility govern bifurcation of mammary branches	35
The IQGAP scaffolds: Critical nodes bridging receptor activation to cellular signaling	34
Vav independently regulates synaptic growth and plasticity through distinct actin-based processes	34
Repression of CENP-A assembly in metaphase requires HJURP phosphorylation and inhibition by M18BP1	34
Septin-mediated RhoA activation engages the exocyst complex to recruit the cilium transition zone	34
Understanding microtubule dynamics: The synergy of technology, theory, and experiment	34
Force tuning through regulation of clathrin-dependent integrin endocytosis	34
StableMARK-decorated microtubules in cells have expanded lattices	34

A fluorogenic complementation tool kit for interrogating lipid droplet–organelle interaction	33
Reticular adhesions are assembled at flat clathrin lattices and opposed by active integrin α5β1	33
Mitochondrial fission controls astrocyte morphogenesis and organization in the cortex	33
Centralspindlin proteins Pavarotti and Tumbleweed along with WASH regulate nuclear envelope budding	33
Correction: Netrins and neogenin promote myotube formation	33
ER-localized Shr3 is a selective co-translational folding chaperone necessary for amino acid permease biogenesis	33
A guide to membrane atg8ylation and autophagy with reflections on immunity	33
A covalently linked probe to monitor local membrane properties surrounding plasma membrane proteins	32
LC3B is a cofactor for LMX1B-mediated transcription of autophagy genes in dopaminergic neurons	32
Spindle morphology changes between meiosis and mitosis driven by CK2 regulation of the Ran pathway	32
Plan your trip before you leave: The neutrophils’ search-and-run journey	32
Hyperstabilization of T cell microvilli contacts by chimeric antigen receptors	32
A Lifeact-EGFP quail for studying actin dynamics in vivo	32
Coronin 1C restricts endosomal branched actin to organize ER contact and endosome fission	32
The role of midbody-associated mRNAs in regulating abscission	32
A membrane-sensing mechanism links lipid metabolism to protein degradation at the nuclear envelope	32
Mitochondria–ER–PM contacts regulate mitochondrial division and PI(4)P distribution	31
Irg1l regulates neuromast size via metabolic reprogramming to promote supporting cell proliferation	31
SUMOylation at the inner nuclear membrane facilitates nuclear envelope biogenesis during mitosis	31
T cells use focal adhesions to pull themselves through confined environments	31
Interphase microtubule disassembly is a signaling cue that drives cell rounding at mitotic entry	31
Axonal transport of autophagosomes is regulated by dynein activators JIP3/JIP4 and ARF/RAB GTPases	30
ATG9A facilitates the closure of mammalian autophagosomes	30
The low-density lipoprotein receptor–mTORC1 axis coordinates CD8+ T cell activation	30
RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursors	30
Autolysosomal exocytosis of lipids protect neurons from ferroptosis	30
The bioenergetics of nucleocytoplasmic transport	29
Endosomal recycling defects link Huntington’s disease with McLeod syndrome	29
Sara Wickström: The forces controlling our cell fate	29
Efficient progranulin exit from the ER requires its interaction with prosaposin, a Surf4 cargo	29
Synaptotagmin-1 in phase: Condensate biology reveals new insights into the synaptic calcium sensor	29
Microtubule-associated proteins promote microtubule generation in the absence of γ-tubulin in human colon cancer cells	28
Faa1 membrane binding drives positive feedback in autophagosome biogenesis via fatty acid activation	28
Periodic changes of cyclin D1 mRNA stability are regulated by PC4 modifications in the cell cycle	28
New insights into IRE1α activation and function in anti-tumor immunity	28
A proteome-wide yeast degron collection for the dynamic study of protein function	28
OMA1 clears traffic jam in TOM tunnel in mammals	28
A farnesyl-dependent structural role for CENP-E in expansion of the fibrous corona	27
Composition and organization of kinetochores show plasticity in apicomplexan chromosome segregation	27
PEAK1 Y635 phosphorylation regulates cell migration through association with Tensin3 and integrins	27
Lactylation stabilizes TFEB to elevate autophagy and lysosomal activity	27
Mechanical control of osteoclast fusion by membrane-cortex attachment and BAR proteins	27
How do trypanosome IFT trains choose special tracks?	26
Inhibition of endolysosome fusion increases exosome secretion	26
Fusion pore dynamics of large secretory vesicles define a distinct mechanism of exocytosis	26
Not just protons: Chloride also activates lysosomal acidic hydrolases	25
Kinesin-1 autoinhibition facilitates the initiation of dynein cargo transport	25
Nodal modulator (NOMO) is a force-bearing transmembrane protein required for muscle differentiation	25
Centrosome age breaks spindle size symmetry even in cells thought to divide symmetrically	25
Meiotic nuclear pore complex remodeling provides key insights into nuclear basket organization	25
Super-resolution microscopy: Insights into mitochondria–lysosome crosstalk in health and disease	25
Extracellular vesicles adhere to cells primarily by interactions of integrins and GM1 with laminin	25
A plant-specific bridging adaptor for amphisome biogenesis	24
Endothelial depletion of Atg7 triggers astrocyte–microvascular disassociation at blood–brain barrier	24
Engineered synaptic tools reveal localized cAMP signaling in synapse assembly	24
Visualizing ER-phagy and ER architecture in vivo	24
Prolonged depletion of profilin 1 or F-actin causes an adaptive response in microtubules	24
The p97 ATPase and its adaptor UBXD8 maintain peroxisome pools by preventing pexophagy	24
Nuclear pore complexes mediate subtelomeric gene silencing by regulating PCNA levels on chromatin	24
NuMA is a mitotic adaptor protein that activates dynein and connects it to microtubule minus ends	24
Cell polarity changes in cancer initiation and progression	23
Integration of cell wall synthesis and chromosome segregation during cell division in Caulobacter	23
The autophagy protein ATG-9 regulates lysosome function and integrity	23
Tailored assemblies of COPII proteins in secretion	23
Karyopherin enrichment and compensation fortifies the nuclear pore complex against nucleocytoplasmic leakage	23
Splicing under stress: A matter of time and place	23
Lena Ho: Micropeptides under the spotlight	22
Making lipids very unhappy to discover how they bind to proteins	22
JIP4 and RILPL1 utilize opposing motor force to dynamically regulate lysosomal tubulation	22
Tension-induced suppression of allosteric conformational changes coordinates kinesin-1 stepping	22
Structural characterization and inhibition of the interaction between ch-TOG and TACC3	22
Atg39 links and deforms the outer and inner nuclear membranes in selective autophagy of the nucleus	21
Sarm1 activation produces cADPR to increase intra-axonal Ca++ and promote axon degeneration in PIPN	21
Phosphoproteomic identification of Mos–MAPK targets in meiotic cell cycle and asymmetric oocyte divisions	21
Ubiquitin ligase MARCH5 localizes to peroxisomes to regulate pexophagy	21
Rickettsia parkeri forms extensive, stable contacts with the rough endoplasmic reticulum	21
Lineage tracing clarifies the cellular origin of tissue-resident macrophages in the developing heart	21
Ca2+ binding to Esyt modulates membrane contact site density in Drosophila photoreceptors	21
Painting lysosomes to study organelle heterogeneity	21
Active RB causes visible changes in nuclear organization	21

α-Catenin force-sensitive binding and sequestration of LZTS2 leads to cytokinesis failure	21
CDR2 is a dynein adaptor recruited by kinectin to regulate ER sheet organization	21
Clathrin: Bender or bystander?	21
Ubiquitinating the way to T cell metabolism	21
LYSMD proteins promote activation of Rab32-family GTPases for lysosome-related organelle biogenesis	21
Binucleated human hepatocytes arise through late cytokinetic regression during endomitosis M phase	21
An interaction between β′-COP and the ArfGAP, Glo3, maintains post-Golgi cargo recycling	21
Tubulin isotypes contribute opposing properties to balance anaphase spindle morphogenesis	21
Establishing spatial control over TORC1 signaling	20
RFWD3 promotes ZRANB3 recruitment to regulate the remodeling of stalled replication forks	20
ER as master regulator of membrane trafficking and organelle function	20
CEP97 phosphorylation by Dyrk1a is critical for centriole separation during multiciliogenesis	20
Plasticity of mitotic cyclins in promoting the G2–M transition	20
p24 family Tango(1) at the endoplasmic reticulum exit site to organize cargo exit	20
Centriole growth is limited by the Cdk/Cyclin-dependent phosphorylation of Ana2/STIL	20
Correction: Stressed-out yeast do not pass GO	20
PI(4,5)P2 diffuses freely in the plasma membrane even within high-density effector protein complexes	20
Structural response of microtubule and actin cytoskeletons to direct intracellular load	20
Directed stochasticity: Building biomolecular condensates in the right place	20
Murine glial protrusion transcripts predict localized Drosophila glial mRNAs involved in plasticity	20
APOE traffics to astrocyte lipid droplets and modulates triglyceride saturation and droplet size	20
The emerging roles of non-canonical ubiquitination in proteostasis and beyond	20
PEX14 acts as a molecular link between optineurin and the autophagic machinery to induce pexophagy	20
Fission-independent compartmentalization of mitochondria during budding yeast cell division	20
Determining how many cells to average for statistical testing of microscopy experiments	20
mTORC2 suppresses cell death induced by hypo-osmotic stress by promoting sphingomyelin transport	19
The minus-end depolymerase KIF2A drives flux-like treadmilling of γTuRC-uncapped microtubules	19
Long live lamins	19
Centrosome-organized plasma membrane infoldings linked to growth of a cortical actin domain	19
Tepsin and AP4 mediate transport from the trans-Golgi to the plant-like vacuole in toxoplasma	19
A specialized tyrosine-based endocytosis signal in MR1 controls antigen presentation to MAIT cells	19
Bridging condensins mediate compaction of mitotic chromosomes	19
NME3 binds to phosphatidic acid and mediates PLD6-induced mitochondrial tethering	19
CLASPs stabilize the pre-catastrophe intermediate state between microtubule growth and shrinkage	19
ARHGAP17 regulates the spatiotemporal activity of Cdc42 at invadopodia	19
Nuclear poly-glutamine aggregates rupture the nuclear envelope and hinder its repair	19
IRSp53 promotes postsynaptic density formation and actin filament bundling	19
Deep learning techniques and mathematical modeling allow 3D analysis of mitotic spindle dynamics	19
Early proteostasis of caveolins synchronizes trafficking, degradation, and oligomerization to prevent toxic aggregation	19
Unveiling the TRAPP: The role of plant TRAPPII in adaptive growth decisions	18
Claudin 7 suppresses invasion and metastasis through repression of a smooth muscle actin program	18
Balancing cell polarity PARts through dephosphorylation	18
RTN3 and RTN4: Architects of SARS-CoV-2 replication organelles	18
ARF3 weights the balance for prostate cancer metastasis	18
Oiling the wheels of nuclear division: SUMOylation regulates the expansion of the mitotic nuclear membrane	18
Tweaking neural organoids to model human reactive astrocytes	18
ISWI chromatin remodeling complexes recruit NSD2 and H3K36me2 in pericentromeric heterochromatin	18
The Ndc80-Cdt1-Ska1 complex is a central processive kinetochore–microtubule coupling unit	18
Mechanosensitive calcium flashes promote sustained RhoA activation during tight junction remodeling	18
Molding a PI(3,5)P2 biosensor	18
One step 4× and 12× 3D-ExM enables robust super-resolution microscopy of nanoscale cellular structures	18
Ribbon boosts ribosomal protein gene expression to coordinate organ form and function	18
Nanoscale architect: Illuminating the key organizer of the fruit fly’s sensory world	18
Liquid–liquid phase separation mediates the formation of herpesvirus assembly compartments	18
Vinculin is required for interkinetic nuclear migration (INM) and cell cycle progression	18
SIR telomere silencing depends on nuclear envelope lipids and modulates sensitivity to a lysolipid	17
Protein Kinase C promotes peroxisome biogenesis and peroxisome–endoplasmic reticulum interaction	17
Vacuolar pH regulates clathrin-mediated endocytosis through TORC1 signaling during replicative aging	17
AMPK regulates phagophore-to-autophagosome maturation	17
JIP3 interacts with dynein and kinesin-1 to regulate bidirectional organelle transport	17
SHIP164 is a chorein motif lipid transfer protein that controls endosome–Golgi membrane traffic	17
WAVE complex forms linear arrays at negative membrane curvature to instruct lamellipodia formation	17
RAB-10 cooperates with EHBP-1 to capture vesicular carriers during post-Golgi exocytic trafficking	17
Zn2+ decoration of microtubules arrests axonal transport and displaces tau, doublecortin, and MAP2C	17
LGI3/2–ADAM23 interactions cluster Kv1 channels in myelinated axons to regulate refractory period	17
Chasing the right tail: How the ER membrane complex recognizes its substrates	17
A collagen IV fluorophore knock-in toolkit reveals trimer diversity in C. elegans basement membranes	17
FUT8-mediated core fucosylation stabilizes TMEM67 to promote ciliogenesis	17
VASH1–SVBP and VASH2–SVBP generate different detyrosination profiles on microtubules	17
Expanded directly binds conserved regions of Fat to restrain growth via the Hippo pathway	17
Postsynaptic BMP signaling regulates myonuclear properties in Drosophila larval muscles	17
Multifaceted modes of γ-tubulin complex recruitment and microtubule nucleation at mitotic centrosomes	16
A versatile cortical pattern-forming circuit based on Rho, F-actin, Ect2, and RGA-3/4	16
Kinetochores get a grip!	16
Cytoplasmic ribosomes on mitochondria alter the local membrane environment for protein import	16
ER export via SURF4 uses diverse mechanisms of both client and coat engagement	16
Small lipid droplets are rigid enough to indent a nucleus, dilute the lamina, and cause rupture	16
Senataxin deficiency disrupts proteostasis through nucleolar ncRNA-driven protein aggregation	16
Cargo adaptors use a handhold mechanism to engage with myosin V for organelle transport	16
Fascin-induced bundling protects actin filaments from disassembly by cofilin	16
Successful 3D imaging of cleared biological samples with light sheet fluorescence microscopy	16
An S-acylated N-terminus and a conserved loop regulate the activity of the ABHD17 deacylase	16
A substrate-interacting region of Parkin directs ubiquitination of the mitochondrial GTPase Miro1	16
α-Catenin links integrin adhesions to F-actin to regulate ECM mechanosensing and rigidity dependence	16
The atlastin paralogs: The complexity in the tails	16
Ubiquitin chain variability directs substrates of the Tul1 ubiquitin ligase complex to different degradation pathways	16
The C10orf76–PI4KB axis orchestrates CERT-mediated ceramide trafficking to the distal Golgi	16
SEPTIN9 locally activates the RhoGEF ARHGEF18 to promote early stages of mitochondrial fission	16
IFT trains overcome an NPHP module barrier at the transition zone	16
Regulation of Cajal bodies: Unexpected connection to 60S ribosomes	16
Endomembranes promote chromosome missegregation by ensheathing misaligned chromosomes	16
A pyrophosphatase that regulates lipid precursors of N-glycosylation	16
The septin cytoskeleton: Heteromer composition defines filament function	16
A second chance at yeast early endosomes	16
Acetic acid–induced stress granules function as scaffolding complexes for Hog1 activation by Pbs2	16