Journal of Cell Biology

Article	Citations
LNCcation: lncRNA localization and function	783
Mitochondrial regulation of ferroptosis	273
Lysosome biogenesis: Regulation and functions	223
The cell biology of synapse formation	189
Paradoxical roles of caspase-3 in regulating cell survival, proliferation, and tumorigenesis	167
STING induces LC3B lipidation onto single-membrane vesicles via the V-ATPase and ATG16L1-WD40 domain	109
Lipid droplets in the nervous system	108
TMEM41B and VMP1 are scramblases and regulate the distribution of cholesterol and phosphatidylserine	105
FUS-dependent liquid–liquid phase separation is important for DNA repair initiation	104
Who’s in control? Principles of Rab GTPase activation in endolysosomal membrane trafficking and beyond	101
Mechanisms of nonvesicular lipid transport	98
VPS13D bridges the ER to mitochondria and peroxisomes via Miro	95
The cell biology of Parkinson’s disease	90
Recognition of RNA by the S9.6 antibody creates pervasive artifacts when imaging RNA:DNA hybrids	88
Endosomal escape of delivered mRNA from endosomal recycling tubules visualized at the nanoscale	83
Sequential dynein effectors regulate axonal autophagosome motility in a maturation-dependent pathway	80
3D FIB-SEM reconstruction of microtubule–organelle interaction in whole primary mouse β cells	73
V-ATPase is a universal regulator of LC3-associated phagocytosis and non-canonical autophagy	73
COPII collar defines the boundary between ER and ER exit site and does not coat cargo containers	72
Similarities and interplay between senescent cells and macrophages	72
Secretory autophagy maintains proteostasis upon lysosome inhibition	71
Phase separation of Axin organizes the β-catenin destruction complex	66
Pathogenic mutations in the kinesin-3 motor KIF1A diminish force generation and movement through allosteric mechanisms	65
PINK1 drives production of mtDNA-containing extracellular vesicles to promote invasiveness	62
Time-resolved proteomics profiling of the ciliary Hedgehog response	61

The long journey to bring a Myc inhibitor to the clinic	61
High-fidelity reconstitution of stress granules and nucleoli in mammalian cellular lysate	60
Nuclear lipid droplets form in the inner nuclear membrane in a seipin-independent manner	56
High-content imaging-based pooled CRISPR screens in mammalian cells	56
Ubiquitin chains earmark GPCRs for BBSome-mediated removal from cilia	55
Transmembrane phospholipid translocation mediated by Atg9 is involved in autophagosome formation	53
Image-based pooled whole-genome CRISPRi screening for subcellular phenotypes	52
Sarm1 activation produces cADPR to increase intra-axonal Ca++ and promote axon degeneration in PIPN	52
VPS13D promotes peroxisome biogenesis	51
Polo-like kinase 1 independently controls microtubule-nucleating capacity and size of the centrosome	51
NCOA4 drives ferritin phase separation to facilitate macroferritinophagy and microferritinophagy	49
Catalytically inactive, purified RNase H1: A specific and sensitive probe for RNA–DNA hybrid imaging	48
Regulation of Golgi turnover by CALCOCO1-mediated selective autophagy	47
Binding and transport of SFPQ-RNA granules by KIF5A/KLC1 motors promotes axon survival	47
ER as master regulator of membrane trafficking and organelle function	47
ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling	47
Phagosome resolution regenerates lysosomes and maintains the degradative capacity in phagocytes	46
SAMM50 acts with p62 in piecemeal basal- and OXPHOS-induced mitophagy of SAM and MICOS components	45
Direct binding of ESCRT protein Chm7 to phosphatidic acid–rich membranes at nuclear envelope herniations	44
DOT1L modulates the senescence-associated secretory phenotype through epigenetic regulation of IL1A	43
Structural and biochemical insights into lipid transport by VPS13 proteins	43
ORP5 and ORP8 orchestrate lipid droplet biogenesis and maintenance at ER–mitochondria contact sites	42
Synaptic activity controls autophagic vacuole motility and function in dendrites	42
Computational analyses reveal spatial relationships between nuclear pore complexes and specific lamins	42
A guide to membrane atg8ylation and autophagy with reflections on immunity	41
mTORC1 activity is supported by spatial association with focal adhesions	41
FHL2 anchors mitochondria to actin and adapts mitochondrial dynamics to glucose supply	40
The WAVE complex associates with sites of saddle membrane curvature	40
PI4P/PS countertransport by ORP10 at ER–endosome membrane contact sites regulates endosome fission	40
Mechanosensitive calcium flashes promote sustained RhoA activation during tight junction remodeling	40
Label-retention expansion microscopy	40
Caveolin-1 and cavin1 act synergistically to generate a unique lipid environment in caveolae	40
Rapid degradation of GRASP55 and GRASP65 reveals their immediate impact on the Golgi structure	39
The modified mitochondrial outer membrane carrier MTCH2 links mitochondrial fusion to lipogenesis	39
ATG9 vesicles comprise the seed membrane of mammalian autophagosomes	39
Quantitative correlative microscopy reveals the ultrastructural distribution of endogenous endosomal proteins	39
Ubiquitin ligase MARCH5 localizes to peroxisomes to regulate pexophagy	38
A cryo-ET survey of microtubules and intracellular compartments in mammalian axons	37
Neuronal endolysosomal transport and lysosomal functionality in maintaining axonostasis	37
Long-lived mitochondrial cristae proteins in mouse heart and brain	37
Cnm1 mediates nucleus–mitochondria contact site formation in response to phospholipid levels	37
GOLPH3 and GOLPH3L are broad-spectrum COPI adaptors for sorting into intra-Golgi transport vesicles	37
Vps13-like proteins provide phosphatidylethanolamine for GPI anchor synthesis in the ER	37
Lipid droplets and the host–pathogen dynamic: FATal attraction?	37
The Rab7 effector WDR91 promotes autophagy-lysosome degradation in neurons by regulating lysosome fusion	37
High-precision targeting workflow for volume electron microscopy	37
Kinetochore-bound Mps1 regulates kinetochore–microtubule attachments via Ndc80 phosphorylation	36
NBR1: The archetypal selective autophagy receptor	36
Angulin-1 seals tricellular contacts independently of tricellulin and claudins	36
MICAL2 enhances branched actin network disassembly by oxidizing Arp3B-containing Arp2/3 complexes	36

Intracellular wetting mediates contacts between liquid compartments and membrane-bound organelles	36
XMAP215 promotes microtubule catastrophe by disrupting the growing microtubule end	35
Specific KIF1A–adaptor interactions control selective cargo recognition	35
USP19 promotes hypoxia-induced mitochondrial division via FUNDC1 at ER-mitochondria contact sites	35
A mitochondrial contribution to anti-inflammatory shear stress signaling in vascular endothelial cells	34
Subcellular localization of the J-protein Sis1 regulates the heat shock response	34
VMP1 and TMEM41B are essential for DMV formation during β-coronavirus infection	34
Optogenetic activators of apoptosis, necroptosis, and pyroptosis	34
Quantitative analysis of autophagy reveals the role of ATG9 and ATG2 in autophagosome formation	34
Plectin-mediated cytoskeletal crosstalk controls cell tension and cohesion in epithelial sheets	34
PLCγ1 promotes phase separation of T cell signaling components	34
Mitochondria on the move: Horizontal mitochondrial transfer in disease and health	34
A non-canonical Hedgehog pathway initiates ciliogenesis and autophagy	33
C-ferroptosis is an iron-dependent form of regulated cell death in cyanobacteria	33
Capture and delivery of tail-anchored proteins to the endoplasmic reticulum	33
The UPRmt preserves mitochondrial import to extend lifespan	33
Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination	33
Opposing functions for retromer and Rab11 in extracellular vesicle traffic at presynaptic terminals	33
Cell migration orchestrates migrasome formation by shaping retraction fibers	32
ANO5 ensures trafficking of annexins in wounded myofibers	32
Centriole-independent mitotic spindle assembly relies on the PCNT–CDK5RAP2 pericentriolar matrix	32
CRISPR screens for lipid regulators reveal a role for ER-bound SNX13 in lysosomal cholesterol export	32
CENP-A overexpression promotes aneuploidy with karyotypic heterogeneity	32
Liquid–liquid phase separation facilitates the biogenesis of secretory storage granules	32
Atg39 links and deforms the outer and inner nuclear membranes in selective autophagy of the nucleus	32
Dendritic cell actin dynamics control contact duration and priming efficiency at the immunological synapse	32
The cell biology of fertilization: Gamete attachment and fusion	31
Stress granules and mTOR are regulated by membrane atg8ylation during lysosomal damage	31
MyD88 oligomer size functions as a physical threshold to trigger IL1R Myddosome signaling	31
Phosphorylation of SNX27 by MAPK11/14 links cellular stress–signaling pathways with endocytic recycling	31
A ciliopathy complex builds distal appendages to initiate ciliogenesis	31
Mitochondrial dysfunction compromises ciliary homeostasis in astrocytes	31
A septin GTPase scaffold of dynein–dynactin motors triggers retrograde lysosome transport	30
Regulating peroxisome–ER contacts via the ACBD5-VAPB tether by FFAT motif phosphorylation and GSK3β	30
WASP integrates substrate topology and cell polarity to guide neutrophil migration	30
SARS-CoV-2 ORF10 impairs cilia by enhancing CUL2ZYG11B activity	30
A versatile cortical pattern-forming circuit based on Rho, F-actin, Ect2, and RGA-3/4	30
GTP-dependent formation of straight tubulin oligomers leads to microtubule nucleation	29
Induction of spontaneous human neocentromere formation and long-term maturation	29
Effector-mediated ERM activation locally inhibits RhoA activity to shape the apical cell domain	29
Consensus nomenclature for dyneins and associated assembly factors	29
Myelination generates aberrant ultrastructure that is resolved by microglia	28
Autophagy facilitates mitochondrial rebuilding after acute heat stress via a DRP-1–dependent process	28
Stochastic combinations of actin regulatory proteins are sufficient to drive filopodia formation	28
Twinfilin bypasses assembly conditions and actin filament aging to drive barbed end depolymerization	28
JIP3 interacts with dynein and kinesin-1 to regulate bidirectional organelle transport	28
STING controls energy stress-induced autophagy and energy metabolism via STX17	28
Vps13D functions in a Pink1-dependent and Parkin-independent mitophagy pathway	28
Regulation of membrane NMDA receptors by dynamics and protein interactions	28
Nano-scale resolution of native retinal rod disk membranes reveals differences in lipid composition	27
TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination	27
The ER cholesterol sensor SCAP promotes CARTS biogenesis at ER–Golgi membrane contact sites	27
Senescent cells suppress macrophage-mediated corpse removal via upregulation of the CD47-QPCT/L axis	27
ER membrane contact sites support endosomal small GTPase conversion for exosome secretion	27
Atlastin 2/3 regulate ER targeting of the ULK1 complex to initiate autophagy	27
EGFR-mediated epidermal stem cell motility drives skin regeneration through COL17A1 proteolysis	26
Centriole and PCM cooperatively recruit CEP192 to spindle poles to promote bipolar spindle assembly	26
Dual spindles assemble in bovine zygotes despite the presence of paternal centrosomes	26
A loop extrusion–independent mechanism contributes to condensin I–mediated chromosome shaping	26
Live imaging of transcription sites using an elongating RNA polymerase II–specific probe	26
Biochemical reconstitutions reveal principles of human γ-TuRC assembly and function	26
FIT2 organizes lipid droplet biogenesis with ER tubule-forming proteins and septins	26
E3 ubiquitin ligase Wwp1 regulates ciliary dynamics of the Hedgehog receptor Smoothened	26
Retinyl esters form lipid droplets independently of triacylglycerol and seipin	25
Teasing out function from morphology: Similarities between primary cilia and immune synapses	25
Cavin4 interacts with Bin1 to promote T-tubule formation and stability in developing skeletal muscle	25
Plk4 triggers autonomous de novo centriole biogenesis and maturation	25
Tension promotes kinetochore–microtubule release by Aurora B kinase	25
Myeloid-derived growth factor regulates neutrophil motility in interstitial tissue damage	25
Poly(ADP-ribose) binding and macroH2A mediate recruitment and functions of KDM5A at DNA lesions	25
Extracellular vesicles from neurons promote neural induction of stem cells through cyclin D1	24
Per1/Per2–Igf2 axis–mediated circadian regulation of myogenic differentiation	24
Shared and specific functions of Arfs 1–5 at the Golgi revealed by systematic knockouts	24
Tricellulin secures the epithelial barrier at tricellular junctions by interacting with actomyosin	24
Parallel phospholipid transfer by Vps13 and Atg2 determines autophagosome biogenesis dynamics	23
The HSPG syndecan is a core organizer of cholinergic synapses	23
CYRI-A limits invasive migration through macropinosome formation and integrin uptake regulation	23
Quality assessment in light microscopy for routine use through simple tools and robust metrics	23
Reduced insulin/IGF1 signaling prevents immune aging via ZIP-10/bZIP–mediated feedforward loop	23
Composition and organization of kinetochores show plasticity in apicomplexan chromosome segregation	23

Detection and quantification of the vacuolar H+ATPase using the Legionella effector protein SidK	23
Triglyceride lipolysis triggers liquid crystalline phases in lipid droplets and alters the LD proteome	23
ZNF416 is a pivotal transcriptional regulator of fibroblast mechanoactivation	23
Mechanical competition alters the cellular interpretation of an endogenous genetic program	23
Signaling by the integrated stress response kinase PKR is fine-tuned by dynamic clustering	23
Quantifying organellar ultrastructure in cryo-electron tomography using a surface morphometrics pipeline	23
Fyn and TOM1L1 are recruited to clathrin-coated pits and regulate Akt signaling	23
Stress-responsive regulation of extracellular proteostasis	23
Phase separation and toxicity of C9orf72 poly(PR) depends on alternate distribution of arginine	23
STED imaging of endogenously tagged ARF GTPases reveals their distinct nanoscale localizations	22
Zc3h10 regulates adipogenesis by controlling translation and F-actin/mitochondria interaction	22
Induced nanoscale membrane curvature bypasses the essential endocytic function of clathrin	22
WDR60-mediated dynein-2 loading into cilia powers retrograde IFT and transition zone crossing	22
An APEX2 proximity ligation method for mapping interactions with the nuclear lamina	22
Chromosome compartmentalization alterations in prostate cancer cell lines model disease progression	22
Nucleoplasmic lamin C rapidly accumulates at sites of nuclear envelope rupture with BAF and cGAS	22
Superresolution characterization of core centriole architecture	22
c entrocortin RNA localization to centrosomes is regulated by FMRP and facilitates error-free mitosis	22
Human septins organize as octamer-based filaments and mediate actin-membrane anchoring in cells	22
Chromosome oscillation promotes Aurora A–dependent Hec1 phosphorylation and mitotic fidelity	22
O-GlcNAc modification of nuclear pore complexes accelerates bidirectional transport	22
An asymmetric junctional mechanoresponse coordinates mitotic rounding with epithelial integrity	22
Material properties of phase-separated TFEB condensates regulate the autophagy-lysosome pathway	22
Sterol and oxysterol synthases near the ciliary base activate the Hedgehog pathway	22
Mitoguardin-2–mediated lipid transfer preserves mitochondrial morphology and lipid droplet formation	22
Centromeric transcription maintains centromeric cohesion in human cells	22
Karyopherin enrichment and compensation fortifies the nuclear pore complex against nucleocytoplasmic leakage	22
ESCRT, not intralumenal fragments, sorts ubiquitinated vacuole membrane proteins for degradation	21
Leep1 interacts with PIP3 and the Scar/WAVE complex to regulate cell migration and macropinocytosis	21
Anisotropic expansion of hepatocyte lumina enforced by apical bulkheads	21
Lymphocyte egress signal sphingosine-1-phosphate promotes ERM-guided, bleb-based migration	21
Plant autophagosomes mature into amphisomes prior to their delivery to the central vacuole	21
Endomembranes promote chromosome missegregation by ensheathing misaligned chromosomes	21
Aurora A kinase activation: Different means to different ends	21
Multivalent interactions make adherens junction–cytoskeletal linkage robust during morphogenesis	21
CAMSAPs organize an acentrosomal microtubule network from basal varicosities in radial glial cells	21
Mechanosensitive collaboration between integrins and connexins allows nutrient and antioxidant transport into the lens	21
EPH/EPHRIN regulates cellular organization by actomyosin contractility effects on cell contacts	21
Development of ultrafast camera-based single fluorescent-molecule imaging for cell biology	21
The deubiquitylase USP9X controls ribosomal stalling	21
Antigen-derived peptides engage the ER stress sensor IRE1α to curb dendritic cell cross-presentation	20
αv-Class integrin binding to fibronectin is solely mediated by RGD and unaffected by an RGE mutation	20
Mechanism of p38 MAPK–induced EGFR endocytosis and its crosstalk with ligand-induced pathways	20
mTORC1 beyond anabolic metabolism: Regulation of cell death	20
Pex30-like proteins function as adaptors at distinct ER membrane contact sites	20
Filament organization of the bacterial actin MreB is dependent on the nucleotide state	20
Coordinated metabolic transitions and gene expression by NAD+ during adipogenesis	20
EGFR-RAS-MAPK signaling is confined to the plasma membrane and associated endorecycling protrusions	20
Kinetoplastid kinetochore proteins KKT2 and KKT3 have unique centromere localization domains	20
DNA damage promotes microtubule dynamics through a DNA-PK-AKT axis for enhanced repair	20
High-throughput single-cell epigenomic profiling by targeted insertion of promoters (TIP-seq)	20
Want to leave the ER? We offer vesicles, tubules, and tunnels	20
In situ cryo-electron tomography reveals local cellular machineries for axon branch development	20
Lysosome damage triggers direct ATG8 conjugation and ATG2 engagement via non-canonical autophagy	20
A novel function for the sperm adhesion protein IZUMO1 in cell–cell fusion	19
KIF13A drives AMPA receptor synaptic delivery for long-term potentiation via endosomal remodeling	19
RanGTP and the actin cytoskeleton keep paternal and maternal chromosomes apart during fertilization	19
PI(4,5)P2 diffuses freely in the plasma membrane even within high-density effector protein complexes	19
Rab2 regulates presynaptic precursor vesicle biogenesis at the trans-Golgi	19
A membrane-sensing mechanism links lipid metabolism to protein degradation at the nuclear envelope	19
Rag GTPases and phosphatidylinositol 3-phosphate mediate recruitment of the AP-5/SPG11/SPG15 complex	19
EpCAM proteolysis and release of complexed claudin-7 repair and maintain the tight junction barrier	19
Atg39 selectively captures inner nuclear membrane into lumenal vesicles for delivery to the autophagosome	19
LPHN2 inhibits vascular permeability by differential control of endothelial cell adhesion	19
Lipid anchoring and electrostatic interactions target NOT-LIKE-DAD to pollen endo-plasma membrane	19
WDR62 regulates spindle dynamics as an adaptor protein between TPX2/Aurora A and katanin	19
Phosphorylation of PKCδ by FER tips the balance from EGFR degradation to recycling	19
TRAIL signaling promotes entosis in colorectal cancer	18
Autoinhibition of Cnn binding to γ-TuRCs prevents ectopic microtubule nucleation and cell division defects	18
Seipin concentrates distinct neutral lipids via interactions with their acyl chain carboxyl esters	18
An ATM–Chk2–INCENP pathway activates the abscission checkpoint	18
TRPC3 channel gating by lipids requires localization at the ER/PM junctions defined by STIM1	18
Developing T cells form an immunological synapse for passage through the β-selection checkpoint	18
LRR1-mediated replisome disassembly promotes DNA replication by recycling replisome components	18
Micronuclei in Kif18a mutant mice form stable micronuclear envelopes and do not promote tumorigenesis	18
Lysosomal solute and water transport	18
High-efficacy subcellular micropatterning of proteins using fibrinogen anchors	18
Mechanisms of actin disassembly and turnover	18
Giantin is required for intracellular N-terminal processing of type I procollagen	17
PERK recruits E-Syt1 at ER–mitochondria contacts for mitochondrial lipid transport and respiration	17
Quality control ensures fidelity in ribosome assembly and cellular health	17
Programmed cortical ER collapse drives selective ER degradation and inheritance in yeast meiosis	17
Phosphorylation-dependent mitotic SUMOylation drives nuclear envelope–chromatin interactions	17
CEP55 promotes cilia disassembly through stabilizing Aurora A kinase	17
Endoplasmic reticulum maintains ion homeostasis required for plasma membrane repair	17
SCF-Fbxo42 promotes synaptonemal complex assembly by downregulating PP2A-B56	17
Ultrafast single-molecule imaging reveals focal adhesion nano-architecture and molecular dynamics	17
Visualizing intra-Golgi localization and transport by side-averaging Golgi ministacks	17
SHIP164 is a chorein motif lipid transfer protein that controls endosome–Golgi membrane traffic	16
Persistent DNA damage signaling and DNA polymerase theta promote broken chromosome segregation	16
Ist2 recruits the lipid transporters Osh6/7 to ER–PM contacts to maintain phospholipid metabolism	16
Mesenchymal-to-epithelial transitions require tissue-specific interactions with distinct laminins	16
Astral microtubule cross-linking safeguards uniform nuclear distribution in the Drosophila syncytium	16
Glypican 4 mediates Wnt transport between germ layers via signaling filopodia	16
Signal strength controls the rate of polarization within CTLs during killing	16