Journal of Cell Biology

Article	Citations
LNCcation: lncRNA localization and function	701
Mitochondrial regulation of ferroptosis	233
Lysosome biogenesis: Regulation and functions	194
The cell biology of synapse formation	169
Paradoxical roles of caspase-3 in regulating cell survival, proliferation, and tumorigenesis	141
Mitophagy pathways in health and disease	127
SARM1 acts downstream of neuroinflammatory and necroptotic signaling to induce axon degeneration	105
TMEM41B and VMP1 are scramblases and regulate the distribution of cholesterol and phosphatidylserine	102
Cancer cells educate natural killer cells to a metastasis-promoting cell state	98
STING induces LC3B lipidation onto single-membrane vesicles via the V-ATPase and ATG16L1-WD40 domain	97
Lipid droplets in the nervous system	97
VPS13D bridges the ER to mitochondria and peroxisomes via Miro	94
FUS-dependent liquid–liquid phase separation is important for DNA repair initiation	94
The RNA binding protein FMR1 controls selective exosomal miRNA cargo loading during inflammation	90
Mechanisms of nonvesicular lipid transport	90
The NLRP3–inflammasome as a sensor of organelle dysfunction	89
The cell biology of Parkinson’s disease	84
Recognition of RNA by the S9.6 antibody creates pervasive artifacts when imaging RNA:DNA hybrids	82
Who’s in control? Principles of Rab GTPase activation in endolysosomal membrane trafficking and beyond	80
Sequential dynein effectors regulate axonal autophagosome motility in a maturation-dependent pathway	74
CDK4/6 regulate lysosome biogenesis through TFEB/TFE3	73
3D FIB-SEM reconstruction of microtubule–organelle interaction in whole primary mouse β cells	69
Endosomal escape of delivered mRNA from endosomal recycling tubules visualized at the nanoscale	67
The proline-rich domain promotes Tau liquid–liquid phase separation in cells	66
COPII collar defines the boundary between ER and ER exit site and does not coat cargo containers	65

Phospholipid ebb and flow makes mitochondria go	65
Similarities and interplay between senescent cells and macrophages	64
Pathogenic mutations in the kinesin-3 motor KIF1A diminish force generation and movement through allosteric mechanisms	63
Secretory autophagy maintains proteostasis upon lysosome inhibition	63
Phase separation of Axin organizes the β-catenin destruction complex	62
V-ATPase is a universal regulator of LC3-associated phagocytosis and non-canonical autophagy	60
Evolving models for assembling and shaping clathrin-coated pits	60
High-fidelity reconstitution of stress granules and nucleoli in mammalian cellular lysate	58
Time-resolved proteomics profiling of the ciliary Hedgehog response	57
PINK1 drives production of mtDNA-containing extracellular vesicles to promote invasiveness	56
ECM deposition is driven by caveolin-1–dependent regulation of exosomal biogenesis and cargo sorting	56
The long journey to bring a Myc inhibitor to the clinic	56
High-content imaging-based pooled CRISPR screens in mammalian cells	55
Nuclear lipid droplets form in the inner nuclear membrane in a seipin-independent manner	54
Ubiquitin chains earmark GPCRs for BBSome-mediated removal from cilia	53
Role of the early secretory pathway in SARS-CoV-2 infection	50
Image-based pooled whole-genome CRISPRi screening for subcellular phenotypes	50
Transmembrane phospholipid translocation mediated by Atg9 is involved in autophagosome formation	50
VPS13D promotes peroxisome biogenesis	50
Polo-like kinase 1 independently controls microtubule-nucleating capacity and size of the centrosome	46
Adherens junction regulates cryptic lamellipodia formation for epithelial cell migration	45
Sarm1 activation produces cADPR to increase intra-axonal Ca++ and promote axon degeneration in PIPN	45
Binding and transport of SFPQ-RNA granules by KIF5A/KLC1 motors promotes axon survival	44
Catalytically inactive, purified RNase H1: A specific and sensitive probe for RNA–DNA hybrid imaging	44
Direct binding of ESCRT protein Chm7 to phosphatidic acid–rich membranes at nuclear envelope herniations	43
Phagosome resolution regenerates lysosomes and maintains the degradative capacity in phagocytes	42
High-speed single-molecule imaging reveals signal transduction by induced transbilayer raft phases	42
CDC42EP5/BORG3 modulates SEPT9 to promote actomyosin function, migration, and invasion	42
ER as master regulator of membrane trafficking and organelle function	42
SAMM50 acts with p62 in piecemeal basal- and OXPHOS-induced mitophagy of SAM and MICOS components	42
Regulation of Golgi turnover by CALCOCO1-mediated selective autophagy	41
ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling	40
Synaptic activity controls autophagic vacuole motility and function in dendrites	40
mTORC1 activity is supported by spatial association with focal adhesions	39
NCOA4 drives ferritin phase separation to facilitate macroferritinophagy and microferritinophagy	39
DOT1L modulates the senescence-associated secretory phenotype through epigenetic regulation of IL1A	39
Computational analyses reveal spatial relationships between nuclear pore complexes and specific lamins	39
Structural and biochemical insights into lipid transport by VPS13 proteins	39
Mechanosensitive calcium flashes promote sustained RhoA activation during tight junction remodeling	38
HDAC6 regulates microtubule stability and clustering of AChRs at neuromuscular junctions	38
Tyramide signal amplification mass spectrometry (TSA-MS) ratio identifies nuclear speckle proteins	38
FIT2 is an acyl–coenzyme A diphosphatase crucial for endoplasmic reticulum homeostasis	38
Rapid degradation of GRASP55 and GRASP65 reveals their immediate impact on the Golgi structure	38
Caveolin-1 and cavin1 act synergistically to generate a unique lipid environment in caveolae	37
High-precision targeting workflow for volume electron microscopy	37
The modified mitochondrial outer membrane carrier MTCH2 links mitochondrial fusion to lipogenesis	37
Analysis of copy number alterations reveals the lncRNA ALAL-1 as a regulator of lung cancer immune evasion	36
Ubiquitin ligase MARCH5 localizes to peroxisomes to regulate pexophagy	36
Quantitative correlative microscopy reveals the ultrastructural distribution of endogenous endosomal proteins	36
FHL2 anchors mitochondria to actin and adapts mitochondrial dynamics to glucose supply	36

Label-retention expansion microscopy	35
The WAVE complex associates with sites of saddle membrane curvature	35
PI4P/PS countertransport by ORP10 at ER–endosome membrane contact sites regulates endosome fission	35
Angulin-1 seals tricellular contacts independently of tricellulin and claudins	35
A cryo-ET survey of microtubules and intracellular compartments in mammalian axons	35
USP19 promotes hypoxia-induced mitochondrial division via FUNDC1 at ER-mitochondria contact sites	35
Long-lived mitochondrial cristae proteins in mouse heart and brain	35
NBR1: The archetypal selective autophagy receptor	34
XMAP215 promotes microtubule catastrophe by disrupting the growing microtubule end	34
Lipid droplets and the host–pathogen dynamic: FATal attraction?	34
Intracellular wetting mediates contacts between liquid compartments and membrane-bound organelles	34
GOLPH3 and GOLPH3L are broad-spectrum COPI adaptors for sorting into intra-Golgi transport vesicles	34
Nesprins are mechanotransducers that discriminate epithelial–mesenchymal transition programs	33
Telomerase treatment prevents lung profibrotic pathologies associated with physiological aging	33
Specific KIF1A–adaptor interactions control selective cargo recognition	33
Alternative splicing of clathrin heavy chain contributes to the switch from coated pits to plaques	33
Kinetochore-bound Mps1 regulates kinetochore–microtubule attachments via Ndc80 phosphorylation	33
Cnm1 mediates nucleus–mitochondria contact site formation in response to phospholipid levels	33
A non-canonical Hedgehog pathway initiates ciliogenesis and autophagy	33
A guide to membrane atg8ylation and autophagy with reflections on immunity	33
The Rab7 effector WDR91 promotes autophagy-lysosome degradation in neurons by regulating lysosome fusion	33
MICAL2 enhances branched actin network disassembly by oxidizing Arp3B-containing Arp2/3 complexes	33
Optogenetic activators of apoptosis, necroptosis, and pyroptosis	33
Neuronal endolysosomal transport and lysosomal functionality in maintaining axonostasis	33
Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination	32
Capture and delivery of tail-anchored proteins to the endoplasmic reticulum	32
Opposing functions for retromer and Rab11 in extracellular vesicle traffic at presynaptic terminals	32
MICOS subcomplexes assemble independently on the mitochondrial inner membrane in proximity to ER contact sites	32
ORP5 and ORP8 orchestrate lipid droplet biogenesis and maintenance at ER–mitochondria contact sites	32
ER–mitochondria contacts promote mitochondrial-derived compartment biogenesis	32
Plectin-mediated cytoskeletal crosstalk controls cell tension and cohesion in epithelial sheets	31
PLCγ1 promotes phase separation of T cell signaling components	31
mRNA localization mediates maturation of cytoplasmic cilia in Drosophila spermatogenesis	31
Phosphorylation of SNX27 by MAPK11/14 links cellular stress–signaling pathways with endocytic recycling	31
A mitochondrial contribution to anti-inflammatory shear stress signaling in vascular endothelial cells	31
The UPRmt preserves mitochondrial import to extend lifespan	31
Vps13-like proteins provide phosphatidylethanolamine for GPI anchor synthesis in the ER	31
A ciliopathy complex builds distal appendages to initiate ciliogenesis	30
Liquid–liquid phase separation facilitates the biogenesis of secretory storage granules	30
Notch2 complements Notch1 to mediate inductive signaling that initiates early T cell development	30
Atg39 links and deforms the outer and inner nuclear membranes in selective autophagy of the nucleus	30
CRISPR screens for lipid regulators reveal a role for ER-bound SNX13 in lysosomal cholesterol export	30
ANO5 ensures trafficking of annexins in wounded myofibers	30
Subcellular localization of the J-protein Sis1 regulates the heat shock response	30
MyD88 oligomer size functions as a physical threshold to trigger IL1R Myddosome signaling	29
GTP-dependent formation of straight tubulin oligomers leads to microtubule nucleation	29
CENP-A overexpression promotes aneuploidy with karyotypic heterogeneity	29
WASP integrates substrate topology and cell polarity to guide neutrophil migration	29
Induction of spontaneous human neocentromere formation and long-term maturation	29
Dendritic cell actin dynamics control contact duration and priming efficiency at the immunological synapse	29
C-ferroptosis is an iron-dependent form of regulated cell death in cyanobacteria	29
Cell migration orchestrates migrasome formation by shaping retraction fibers	29
Cell division requires RNA eviction from condensing chromosomes	28
Vps13D functions in a Pink1-dependent and Parkin-independent mitophagy pathway	28
Regulating peroxisome–ER contacts via the ACBD5-VAPB tether by FFAT motif phosphorylation and GSK3β	28
Centriole-independent mitotic spindle assembly relies on the PCNT–CDK5RAP2 pericentriolar matrix	28
ATG9 vesicles comprise the seed membrane of mammalian autophagosomes	28
Deorphanizing FAM19A proteins as pan-neurexin ligands with an unusual biosynthetic binding mechanism	28
Kinetochore phosphatases suppress autonomous Polo-like kinase 1 activity to control the mitotic checkpoint	28
A septin GTPase scaffold of dynein–dynactin motors triggers retrograde lysosome transport	27
p53 deficiency triggers dysregulation of diverse cellular processes in physiological oxygen	27
Effector-mediated ERM activation locally inhibits RhoA activity to shape the apical cell domain	27
Evidence for anaphase pulling forces during C. elegans meiosis	27
Consensus nomenclature for dyneins and associated assembly factors	27
Atlastin 2/3 regulate ER targeting of the ULK1 complex to initiate autophagy	27
Mitochondrial dysfunction compromises ciliary homeostasis in astrocytes	27
VMP1 and TMEM41B are essential for DMV formation during β-coronavirus infection	27
TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination	26
Stochastic combinations of actin regulatory proteins are sufficient to drive filopodia formation	26
Biochemical reconstitutions reveal principles of human γ-TuRC assembly and function	26
Twinfilin bypasses assembly conditions and actin filament aging to drive barbed end depolymerization	26
SARS-CoV-2 ORF10 impairs cilia by enhancing CUL2ZYG11B activity	26
NUCKS1 promotes RAD54 activity in homologous recombination DNA repair	26
The ER cholesterol sensor SCAP promotes CARTS biogenesis at ER–Golgi membrane contact sites	26
An antibody toolbox to track complex I assembly defines AIF’s mitochondrial function	26
Myelination generates aberrant ultrastructure that is resolved by microglia	25
Teasing out function from morphology: Similarities between primary cilia and immune synapses	25
JIP3 interacts with dynein and kinesin-1 to regulate bidirectional organelle transport	25
STING controls energy stress-induced autophagy and energy metabolism via STX17	25
Genetically encoded live-cell sensor for tyrosinated microtubules	25

CDKD-dependent activation of CDKA;1 controls microtubule dynamics and cytokinesis during meiosis	25
Live imaging of transcription sites using an elongating RNA polymerase II–specific probe	25
FIT2 organizes lipid droplet biogenesis with ER tubule-forming proteins and septins	25
Quantitative analysis of autophagy reveals the role of ATG9 and ATG2 in autophagosome formation	25
Conserved actin machinery drives microtubule-independent motility and phagocytosis in Naegleria	25
Retinyl esters form lipid droplets independently of triacylglycerol and seipin	24
E3 ubiquitin ligase Wwp1 regulates ciliary dynamics of the Hedgehog receptor Smoothened	24
Shared and specific functions of Arfs 1–5 at the Golgi revealed by systematic knockouts	24
Collective invasion induced by an autocrine purinergic loop through connexin-43 hemichannels	24
Autophagy facilitates mitochondrial rebuilding after acute heat stress via a DRP-1–dependent process	24
ER membrane contact sites support endosomal small GTPase conversion for exosome secretion	24
Plk4 triggers autonomous de novo centriole biogenesis and maturation	24
The cell biology of fertilization: Gamete attachment and fusion	24
Nano-scale resolution of native retinal rod disk membranes reveals differences in lipid composition	24
Regulation of membrane NMDA receptors by dynamics and protein interactions	24
Stress granules and mTOR are regulated by membrane atg8ylation during lysosomal damage	24
Tricellulin secures the epithelial barrier at tricellular junctions by interacting with actomyosin	23
CYRI-A limits invasive migration through macropinosome formation and integrin uptake regulation	23
Dual spindles assemble in bovine zygotes despite the presence of paternal centrosomes	23
Tension promotes kinetochore–microtubule release by Aurora B kinase	23
Stable inheritance of CENP-A chromatin: Inner strength versus dynamic control	23
A versatile cortical pattern-forming circuit based on Rho, F-actin, Ect2, and RGA-3/4	23
Extracellular vesicles from neurons promote neural induction of stem cells through cyclin D1	23
Per1/Per2–Igf2 axis–mediated circadian regulation of myogenic differentiation	23
Centriole and PCM cooperatively recruit CEP192 to spindle poles to promote bipolar spindle assembly	23
Quality control of 40S ribosome head assembly ensures scanning competence	23
ZNF416 is a pivotal transcriptional regulator of fibroblast mechanoactivation	23
Poly(ADP-ribose) binding and macroH2A mediate recruitment and functions of KDM5A at DNA lesions	23
Object detection networks and augmented reality for cellular detection in fluorescence microscopy	23
A loop extrusion–independent mechanism contributes to condensin I–mediated chromosome shaping	23
Mechanical competition alters the cellular interpretation of an endogenous genetic program	22
Zc3h10 regulates adipogenesis by controlling translation and F-actin/mitochondria interaction	22
WDR60-mediated dynein-2 loading into cilia powers retrograde IFT and transition zone crossing	22
An APEX2 proximity ligation method for mapping interactions with the nuclear lamina	22
Phase separation and toxicity of C9orf72 poly(PR) depends on alternate distribution of arginine	22
Cavin4 interacts with Bin1 to promote T-tubule formation and stability in developing skeletal muscle	22
Mitochondria on the move: Horizontal mitochondrial transfer in disease and health	22
Combinatorial multivalent interactions drive cooperative assembly of the COPII coat	22
An asymmetric junctional mechanoresponse coordinates mitotic rounding with epithelial integrity	22
Intersection of TKS5 and FGD1/CDC42 signaling cascades directs the formation of invadopodia	22
Fyn and TOM1L1 are recruited to clathrin-coated pits and regulate Akt signaling	22
EGFR-mediated epidermal stem cell motility drives skin regeneration through COL17A1 proteolysis	21
Signaling by the integrated stress response kinase PKR is fine-tuned by dynamic clustering	21
Anisotropic expansion of hepatocyte lumina enforced by apical bulkheads	21
c entrocortin RNA localization to centrosomes is regulated by FMRP and facilitates error-free mitosis	21
Quality assessment in light microscopy for routine use through simple tools and robust metrics	21
Karyopherin enrichment and compensation fortifies the nuclear pore complex against nucleocytoplasmic leakage	21
ESCRT, not intralumenal fragments, sorts ubiquitinated vacuole membrane proteins for degradation	21
The HSPG syndecan is a core organizer of cholinergic synapses	21
A conserved myotubularin-related phosphatase regulates autophagy by maintaining autophagic flux	21
Centromeric transcription maintains centromeric cohesion in human cells	21
Reduced insulin/IGF1 signaling prevents immune aging via ZIP-10/bZIP–mediated feedforward loop	21
Detection and quantification of the vacuolar H+ATPase using the Legionella effector protein SidK	21
Sterol and oxysterol synthases near the ciliary base activate the Hedgehog pathway	21
Triglyceride lipolysis triggers liquid crystalline phases in lipid droplets and alters the LD proteome	21
Stress-responsive regulation of extracellular proteostasis	21
Mechanosensitive collaboration between integrins and connexins allows nutrient and antioxidant transport into the lens	20
Mechanism of p38 MAPK–induced EGFR endocytosis and its crosstalk with ligand-induced pathways	20
Superresolution characterization of core centriole architecture	20
Lymphocyte egress signal sphingosine-1-phosphate promotes ERM-guided, bleb-based migration	20
Novel phospho-switch function of delta-catenin in dendrite development	20
O-GlcNAc modification of nuclear pore complexes accelerates bidirectional transport	20
Leep1 interacts with PIP3 and the Scar/WAVE complex to regulate cell migration and macropinocytosis	20
Senescent cells suppress macrophage-mediated corpse removal via upregulation of the CD47-QPCT/L axis	20
Induced nanoscale membrane curvature bypasses the essential endocytic function of clathrin	20
Pex30-like proteins function as adaptors at distinct ER membrane contact sites	20
The deubiquitylase USP9X controls ribosomal stalling	20
Composition and organization of kinetochores show plasticity in apicomplexan chromosome segregation	20
Myeloid-derived growth factor regulates neutrophil motility in interstitial tissue damage	20
Aurora A kinase activation: Different means to different ends	20
Multivalent interactions make adherens junction–cytoskeletal linkage robust during morphogenesis	20
Inhibition of class I PI3K enhances chaperone-mediated autophagy	20
Lysine acetylation of cytoskeletal proteins: Emergence of an actin code	19
Filament organization of the bacterial actin MreB is dependent on the nucleotide state	19
CAMSAPs organize an acentrosomal microtubule network from basal varicosities in radial glial cells	19
Material properties of phase-separated TFEB condensates regulate the autophagy-lysosome pathway	19
EPH/EPHRIN regulates cellular organization by actomyosin contractility effects on cell contacts	19
Chromosome oscillation promotes Aurora A–dependent Hec1 phosphorylation and mitotic fidelity	19
Chromosome compartmentalization alterations in prostate cancer cell lines model disease progression	19
Nucleoplasmic lamin C rapidly accumulates at sites of nuclear envelope rupture with BAF and cGAS	19
Parallel phospholipid transfer by Vps13 and Atg2 determines autophagosome biogenesis dynamics	19
In situ cryo-electron tomography reveals local cellular machineries for axon branch development	19
Kinetoplastid kinetochore proteins KKT2 and KKT3 have unique centromere localization domains	19
High-throughput single-cell epigenomic profiling by targeted insertion of promoters (TIP-seq)	19
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality	19
The LTB4–BLT1 axis regulates actomyosin and β2-integrin dynamics during neutrophil extravasation	19
EGFR-RAS-MAPK signaling is confined to the plasma membrane and associated endorecycling protrusions	19
DNA damage promotes microtubule dynamics through a DNA-PK-AKT axis for enhanced repair	19
Want to leave the ER? We offer vesicles, tubules, and tunnels	18
WDR62 regulates spindle dynamics as an adaptor protein between TPX2/Aurora A and katanin	18
Lipid anchoring and electrostatic interactions target NOT-LIKE-DAD to pollen endo-plasma membrane	18
Mitotic phosphorylation of Pex14p regulates peroxisomal import machinery	18
Atg39 selectively captures inner nuclear membrane into lumenal vesicles for delivery to the autophagosome	18
High-efficacy subcellular micropatterning of proteins using fibrinogen anchors	18
KIF13A drives AMPA receptor synaptic delivery for long-term potentiation via endosomal remodeling	18