Journal of Cell Biology

Article	Citations
Neuronal cadherins: The keys that unlock layer-specific astrocyte identity?	284
Bridging condensins mediate compaction of mitotic chromosomes	238
Developmental pruning of sensory neurites by mechanical tearing in Drosophila	193
Tubulin isotype regulation maintains asymmetric requirement for α-tubulin over β-tubulin	189
Preventing aneuploidy: The groom must wait until the bride is ready	117
Sheldon Penman: Visionary of cell form and function	113
Establishing spatial control over TORC1 signaling	105
Ubiquitinating the way to T cell metabolism	104
Pre-T cell receptor localization and trafficking are independent of its signaling	98
Forebrain Eml1 depletion reveals early centrosomal dysfunction causing subcortical heterotopia	95
The abscission checkpoint senses chromatin bridges through Top2α recruitment to DNA knots	95
Signal strength controls the rate of polarization within CTLs during killing	92
Plastin 3 rescues BDNF-TrkB signaling in spinal muscular atrophy	88
zapERtrap: A light-regulated ER release system reveals unexpected neuronal trafficking pathways	80
Clathrin coated pits as signaling platforms for Akt signaling	76
Lack of Paxillin phosphorylation promotes single-cell migration in vivo	72
Border cell polarity and collective migration require the spliceosome component Cactin	71
Toxoplasma ERK7 protects the apical complex from premature degradation	66
IFNγ: Priming for death	62
Nedd4-2-dependent regulation of astrocytic Kir4.1 and Connexin43 controls neuronal network activity	61
Dissecting protein tyrosine phosphatase signaling by engineered chemogenetic control of its activity	61
Ultra high-speed single-molecule fluorescence imaging	56
The ides of MARCH5: The E3 ligase essential for peroxisome degradation by pexophagy	52
Sara Cuylen-Haering: Cellular soaps to keep neat chromosomes	51
Tubulin isotypes optimize distinct spindle positioning mechanisms during yeast mitosis	50

The dynamic instability of actin filament barbed ends	50
Regulated targeting of the monotopic hairpin membrane protein Erg1 requires the GET pathway	48
Filippo Giancotti: Of integrins, signaling, and risotto	47
Mesenchymal-to-epithelial transitions require tissue-specific interactions with distinct laminins	46
Conformational transitions of the Spindly adaptor underlie its interaction with Dynein and Dynactin	46
A collective strategy to promote the dissemination of single cancer cells	45
Prion-like domains drive CIZ1 assembly formation at the inactive X chromosome	44
Hepatocyte apical bulkheads provide a mechanical means to oppose bile pressure	44
Quality assessment in light microscopy for routine use through simple tools and robust metrics	43
p24 family Tango(1) at the endoplasmic reticulum exit site to organize cargo exit	43
High-precision targeting workflow for volume electron microscopy	42
Persistent DNA damage signaling and DNA polymerase theta promote broken chromosome segregation	42
IRE1α recognizes a structural motif in cholera toxin to activate an unfolded protein response	42
Phosphorylation of SNX27 by MAPK11/14 links cellular stress–signaling pathways with endocytic recycling	42
Coordination of RAB-8 and RAB-11 during unconventional protein secretion	41
PTEN is both an activator and a substrate of chaperone-mediated autophagy	41
IRSp53 promotes postsynaptic density formation and actin filament bundling	40
Long live lamins	40
Reconstitution and mechanistic dissection of the human microtubule branching machinery	40
Sugar-free synapses run on mitochondrial Sirtuin 3	40
VPS13B is localized at the interface between Golgi cisternae and is a functional partner of FAM177A1	40
Integrin-based adhesion compartmentalizes ALK3 of the BMPRII to control cell adhesion and migration	40
Starting a lab during the COVID-19 pandemic	40
Tumor suppressor BAP1 nuclear import is governed by transportin-1	40
Kinesin-4 optimizes microtubule orientations for responsive tip growth guidance in moss	39
Rab40–Cullin5 complex regulates EPLIN and actin cytoskeleton dynamics during cell migration	39
Building the centrosome: PLK-1 controls multimerization of SPD-5	39
WDR62 localizes katanin at spindle poles to ensure synchronous chromosome segregation	39
A TRCky TA protein delivery service snubs the UPS	38
Fluorescence lifetime sorting reveals tunable enzyme interactions within cytoplasmic condensates	37
Dendrite remodeling according to GARP	37
Hongyuan Yang: Tracking lipids, one droplet at a time	37
Distinct roles of two homologous kinesins in mammalian motile cilia	37
Fine-tuning activity-dependent bulk endocytosis via kinases and phosphatases	37
Gaia Pigino: Inside the cell	37
Temporal and spatial metabolite dynamics impart control in adipogenesis	37
Tld1 is a regulator of triglyceride lipolysis that demarcates a lipid droplet subpopulation	37
Cnm1: A bridge between mitochondria and nuclear ER	37
Nuclear-enriched protein phosphatase 4 ensures outer kinetochore assembly prior to nuclear dissolution	36
Gradient tracking in mating yeast depends on Bud1 inactivation and actin-independent vesicle delivery	36
Reticulons promote formation of ER-derived double-membrane vesicles that facilitate SARS-CoV-2 replication	36
mmBCFA C17iso ensures endoplasmic reticulum integrity for lipid droplet growth	35
DOT1L modulates the senescence-associated secretory phenotype through epigenetic regulation of IL1A	35
Matriptase drives dissemination of ovarian cancer spheroids by a PAR-2/PI3K/Akt/MMP9 signaling axis	35
How micron-sized exocrine vesicles release content: A comparison with sub-micron endocrine vesicles	35
Determining how many cells to average for statistical testing of microscopy experiments	34
CRISPR screens for lipid regulators reveal a role for ER-bound SNX13 in lysosomal cholesterol export	34
Centromeric transcription maintains centromeric cohesion in human cells	34
Endoplasmic reticulum maintains ion homeostasis required for plasma membrane repair	34
Synapses have autophagy under control	33

An evolutionarily conserved AnkyrinG-dependent motif clusters axonal K2P K+ channels	33
Differential metabolism of arsenicals regulates Fps1-mediated arsenite transport	33
Lipid exchange at ER–trans-Golgi contact sites governs polarized cargo sorting	33
m6Am methyltransferase PCIF1 negatively regulates ciliation by inhibiting BICD2 expression	32
Treacle and TOPBP1 control replication stress response in the nucleolus	32
GxcM-Fbp17/RacC-WASP signaling regulates polarized cortex assembly in migrating cells via Arp2/3	32
Single-cell chromatin accessibility profiling reveals a self-renewing muscle satellite cell state	32
Mammalian fertilization: Does sperm IZUMO1 mediate fusion as well as adhesion?	32
Nuclear poly-glutamine aggregates rupture the nuclear envelope and hinder its repair	31
An inside job: New roles for ApoE at the lipid droplet	31
PIGB maintains nuclear lamina organization in skeletal muscle of Drosophila	31
EVL and MIM/MTSS1 regulate actin cytoskeletal remodeling to promote dendritic filopodia in neurons	31
Mitochondrial-derived compartments remove surplus proteins from the outer mitochondrial membrane	31
DBF4, not DRF1, is the crucial regulator of CDC7 kinase at replication forks	31
Pex30-like proteins function as adaptors at distinct ER membrane contact sites	31
Polarized localization of kinesin-1 and RIC-7 drives axonal mitochondria anterograde transport	31
RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes	31
Antagonism between Prdm16 and Smad4 specifies the trajectory and progression of pancreatic cancer	30
Cell cycle–independent integration of stress signals by Xbp1 promotes Non-G1/G0 quiescence entry	30
The minus-end depolymerase KIF2A drives flux-like treadmilling of γTuRC-uncapped microtubules	30
Murine glial protrusion transcripts predict localized Drosophila glial mRNAs involved in plasticity	29
ARHGAP17 regulates the spatiotemporal activity of Cdc42 at invadopodia	29
Planar cell polarity induces local microtubule bundling for coordinated ciliary beating	29
VMP1 and TMEM41B are essential for DMV formation during β-coronavirus infection	28
Painting lysosomes to study organelle heterogeneity	28
Atg39 selectively captures inner nuclear membrane into lumenal vesicles for delivery to the autophagosome	28
OMA1 protease eliminates arrested protein import intermediates upon mitochondrial depolarization	28
Directed stochasticity: Building biomolecular condensates in the right place	28
SARS-CoV-2 ORF10 impairs cilia by enhancing CUL2ZYG11B activity	27
Stochastic combinations of actin regulatory proteins are sufficient to drive filopodia formation	27
The role of the AP-1 adaptor complex in outgoing and incoming membrane traffic	27
A close shave: How SARS-CoV-2 induces the loss of cilia	27
Cell migration orchestrates migrasome formation by shaping retraction fibers	27
SUMOylation stabilizes sister kinetochore biorientation to allow timely anaphase	27
AI analysis of super-resolution microscopy: Biological discovery in the absence of ground truth	26
Sirtuin3 ensures the metabolic plasticity of neurotransmission during glucose deprivation	26
Functional midbody assembly in the absence of a central spindle	26
Regulation of adaptive growth decisions via phosphorylation of the TRAPPII complex in Arabidopsis	26
Synaptic activity controls autophagic vacuole motility and function in dendrites	25
The desmosome comes into focus	25
RFWD3 promotes ZRANB3 recruitment to regulate the remodeling of stalled replication forks	25
Sub-membrane actin rings compartmentalize the plasma membrane	25
CaMKII mediates sexually dimorphic synaptic transmission at neuromuscular junctions in C. elegans	25
Rac1-PAK1 regulation of Rab11 cycling promotes junction destabilization	25
LYSMD proteins promote activation of Rab32-family GTPases for lysosome-related organelle biogenesis	25
Elimination of nurse cell nuclei that shuttle into oocytes during oogenesis	25
Mechanisms of actin disassembly and turnover	25
Centriole growth is limited by the Cdk/Cyclin-dependent phosphorylation of Ana2/STIL	24
The emerging roles of non-canonical ubiquitination in proteostasis and beyond	24
APOE traffics to astrocyte lipid droplets and modulates triglyceride saturation and droplet size	24
hGRAD: A versatile “one-fits-all” system to acutely deplete RNA binding proteins from condensates	24
CEP97 phosphorylation by Dyrk1a is critical for centriole separation during multiciliogenesis	24
SUV39H2 epigenetic silencing controls fate conversion of epidermal stem and progenitor cells	23
A lysosomal biogenesis map reveals the cargo spectrum of yeast vacuolar protein targeting pathways	23
Kinetochores grip microtubules with directionally asymmetric strength	23
Angulin-1 seals tricellular contacts independently of tricellulin and claudins	23
LUBAC regulates ciliogenesis by promoting CP110 removal from the mother centriole	23
Joseph G. Gall (1928–2024): Cell biologist, naturalist, and mentor extraordinaire	23
Distinct roles of Kif6 and Kif9 in mammalian ciliary trafficking and motility	23
Engineered kinases as a tool for phosphorylation of selected targets in vivo	23
Poly(ADP-ribose) binding and macroH2A mediate recruitment and functions of KDM5A at DNA lesions	23
p24–Tango1 interactions ensure ER–Golgi interface stability and efficient transport	23
Stress-responsive regulation of extracellular proteostasis	23
Rac1 promotes kidney collecting duct integrity by limiting actomyosin activity	23
Detailing organelle division and segregation in Plasmodium falciparum	23
Lysosome damage triggers direct ATG8 conjugation and ATG2 engagement via non-canonical autophagy	23
Proteolytic regulation of a galectin-3/Lrp1 axis controls osteoclast-mediated bone resorption	22
Assembly of γ-secretase occurs through stable dimers after exit from the endoplasmic reticulum	22
The α-Catenin mechanosensing M region is required for cell adhesion during tissue morphogenesis	22
Long-lived mitochondrial cristae proteins in mouse heart and brain	22
A specialized tyrosine-based endocytosis signal in MR1 controls antigen presentation to MAIT cells	22
ER as master regulator of membrane trafficking and organelle function	22
Structural and biochemical insights into lipid transport by VPS13 proteins	22
Glypican 4 mediates Wnt transport between germ layers via signaling filopodia	22
Stress granules and mTOR are regulated by membrane atg8ylation during lysosomal damage	22
LRR1-mediated replisome disassembly promotes DNA replication by recycling replisome components	22
ADAD2 interacts with RNF17 in P-bodies to repress the Ping-pong cycle in pachytene piRNA biogenesis	22
EpCAM proteolysis and release of complexed claudin-7 repair and maintain the tight junction barrier	22
Ist2 recruits the lipid transporters Osh6/7 to ER–PM contacts to maintain phospholipid metabolism	22
Chromosome oscillation promotes Aurora A–dependent Hec1 phosphorylation and mitotic fidelity	22

Excessive STAU1 condensate drives mTOR translation and autophagy dysfunction in neurodegeneration	22
Eukaryotic initiation factor 6 regulates mechanical responses in endothelial cells	21
Vps13-like proteins provide phosphatidylethanolamine for GPI anchor synthesis in the ER	21
PI(4,5)P2 diffuses freely in the plasma membrane even within high-density effector protein complexes	21
Intracellular wetting mediates contacts between liquid compartments and membrane-bound organelles	21
STING controls energy stress-induced autophagy and energy metabolism via STX17	21
Tensin3 interaction with talin drives the formation of fibronectin-associated fibrillar adhesions	21
PP6 regulation of Aurora A–TPX2 limits NDC80 phosphorylation and mitotic spindle size	21
Dual spindles assemble in bovine zygotes despite the presence of paternal centrosomes	21
mTORC2 suppresses cell death induced by hypo-osmotic stress by promoting sphingomyelin transport	21
Consensus nomenclature for dyneins and associated assembly factors	21
A function of TPL/TBL1-type corepressors is to nucleate the assembly of the preinitiation complex	20
Correction: An early endosome–derived retrograde trafficking pathway promotes secretory granule maturation	20
Alternative mechanisms of Notch activation by partitioning into distinct endosomal domains	20
Lipid droplets in the nervous system	20
Nuclear lamin facilitates collective border cell invasion into confined spaces in vivo	20
Correction: The deubiquitylase USP9X controls ribosomal stalling	20
Structural response of microtubule and actin cytoskeletons to direct intracellular load	20
Fission-independent compartmentalization of mitochondria during budding yeast cell division	20
Correction: Stressed-out yeast do not pass GO	20
NME3 binds to phosphatidic acid and mediates PLD6-induced mitochondrial tethering	20
Cell growth and nutrient availability control the mitotic exit signaling network in budding yeast	20
Nuclei as mechanical bumpers during epithelial remodeling	20
KPNA3 regulates histone locus body formation by modulating condensation and nuclear import of NPAT	20
Diverse microtubule-binding repeats regulate TPX2 activities at distinct locations within the spindle	20
Autologous K63 deubiquitylation within the BRCA1-A complex licenses DNA damage recognition	20
Lysosome biogenesis: Regulation and functions	20
Synergistic anticancer effect by targeting CDK2 and EGFR–ERK signaling	20
The Atg1 complex, Atg9, and Vac8 recruit PI3K complex I to the pre-autophagosomal structure	19
Balancing cell polarity PARts through dephosphorylation	19
Zn2+ decoration of microtubules arrests axonal transport and displaces tau, doublecortin, and MAP2C	19
SMGL-1/NBAS acts as a RAB-8 GEF to regulate unconventional protein secretion	19
The Ndc80-Cdt1-Ska1 complex is a central processive kinetochore–microtubule coupling unit	19
GPI anchors: Regulated as needed	19
Determinants of minor satellite RNA function in chromosome segregation in mouse embryonic stem cells	19
Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking	19
ISWI chromatin remodeling complexes recruit NSD2 and H3K36me2 in pericentromeric heterochromatin	18
The glycoprotein GP130 governs the surface presentation of the G protein–coupled receptor APLNR	18
Riding up the escaLEC-TOR for valvular health	18
Bipartite binding interface recruiting HP1 to chromosomal passenger complex at inner centromeres	18
Live imaging of transcription sites using an elongating RNA polymerase II–specific probe	18
CLPTM1L is a GPI-anchoring pathway component targeted by HCMV	18
Discriminating motilities: Coordinating IFT with flagellar beating patterns	18
Intraflagellar transport speed is sensitive to genetic and mechanical perturbations to flagellar beating	18
The mechanism of Atg15-mediated membrane disruption in autophagy	17
Pluripotency state regulates cytoneme selectivity and self-organization of embryonic stem cells	17
Meiotic resetting of the cellular Sod1 pool is driven by protein aggregation, degradation, and transient LUTI-mediated repression	17
Cell cortex regulation by the planar cell polarity protein Prickle1	17
ER–endosome contacts master the ins and outs of secretory endosomes	17
Cingulin and paracingulin tether myosins-2 to junctions to mechanoregulate the plasma membrane	17
The phospholipids cardiolipin and phosphatidylethanolamine differentially regulate MDC biogenesis	17
Shared and specific functions of Arfs 1–5 at the Golgi revealed by systematic knockouts	17
Autoinhibitory mechanism controls binding of centrosomin motif 1 to γ-tubulin ring complex	17
RanGTP and the actin cytoskeleton keep paternal and maternal chromosomes apart during fertilization	17
Phollow the phosphoinositol: Actin dynamics at the B cell immune synapse	17
EPHecting cell contact by increasing cortical tension	16
Mitochondrial dysfunction triggers actin polymerization necessary for rapid glycolytic activation	16
Migrasomes: Biogenesis, physiological roles, and therapeutic potentials	16
GSK3α phosphorylates dynamin-2 to promote GLUT4 endocytosis in muscle cells	16
Who’s in control? Principles of Rab GTPase activation in endolysosomal membrane trafficking and beyond	16
Margarete Heck (1959–2023): Cell biologist, geneticist, and incandescent social spark	16
Food for thought: How cell adhesion coordinates nutrient sensing	16
Oiling the wheels of nuclear division: SUMOylation regulates the expansion of the mitotic nuclear membrane	16
Vps60 initiates alternative ESCRT-III filaments	16
C17orf80 binds the mitochondrial genome to promote its replication	16
A genome-wide screen links peroxisome regulation with Wnt signaling through RNF146 and TNKS/2	16
Modeling the cell biology of monogenetic intestinal epithelial disorders	16
Ye Tian: Surveilling stress to live longer	16
Fine-tuning stress responses by auxiliary feedback loops that sense damage repair	16
Human septins organize as octamer-based filaments and mediate actin-membrane anchoring in cells	16
ZNF416 is a pivotal transcriptional regulator of fibroblast mechanoactivation	16
MYO18B promotes lysosomal exocytosis by facilitating focal adhesion maturation	16
Nanoscale architect: Illuminating the key organizer of the fruit fly’s sensory world	16
The dynamic recruitment of LAB proteins senses meiotic chromosome axis differentiation in C. elegans	15
A nucleotide diphosphate kinase mediates tethering between mitochondria prior to fusion	15
ARF3 weights the balance for prostate cancer metastasis	15
DDX6 modulates P-body and stress granule assembly, composition, and docking	15
Expanded directly binds conserved regions of Fat to restrain growth via the Hippo pathway	15
Clipping EpCAM to release Claudin-7 for the greater good of the epithelial barrier	15
Recombinant biosensors for multiplex and super-resolution imaging of phosphoinositides	15
DCX-EMAP is a core organizer for the ultrastructure of Drosophila mechanosensory organelles	15
Astrocyte-dependent local neurite pruning in Beat-Va neurons	15
Crosstalk between TGF-β and EGF receptors via direct phosphorylation	15
PtdIns(3,4)P2, Lamellipodin, and VASP coordinate actin dynamics during phagocytosis in macrophages	15
GET pathway mediates transfer of mislocalized tail-anchored proteins from mitochondria to the ER	15
Molding a PI(3,5)P2 biosensor	15
Exchangeable leaders of collectively migrating glioma abuse N-cadherin trafficking	15
An in vivo phosphoregulation paradox for focal adhesions	15
Mitochondrial membrane biogenesis: A new pathway for lipid transport mediated by PERK/E-Syt1 complex	15
Centrosome-organized plasma membrane infoldings linked to growth of a cortical actin domain	15
Early proteostasis of caveolins synchronizes trafficking, degradation, and oligomerization to prevent toxic aggregation	14
Regulating peroxisome–ER contacts via the ACBD5-VAPB tether by FFAT motif phosphorylation and GSK3β	14
SIR telomere silencing depends on nuclear envelope lipids and modulates sensitivity to a lysolipid	14
CLASPs stabilize the pre-catastrophe intermediate state between microtubule growth and shrinkage	14
VASH1–SVBP and VASH2–SVBP generate different detyrosination profiles on microtubules	14