Journal of Cell Biology

Article	Citations
Microtubule-driven cell shape changes and actomyosin flow synergize to position the centrosome	134
Conformational transitions of the Spindly adaptor underlie its interaction with Dynein and Dynactin	123
The α-Catenin mechanosensing M region is required for cell adhesion during tissue morphogenesis	110
A collective strategy to promote the dissemination of single cancer cells	107
Developmental pruning of sensory neurites by mechanical tearing in Drosophila	106
GARLH regulates neuroligin preference for excitatory versus inhibitory synapses	105
DBF4, not DRF1, is the crucial regulator of CDC7 kinase at replication forks	104
PP6 regulation of Aurora A–TPX2 limits NDC80 phosphorylation and mitotic spindle size	104
PAK4 promotes vertex remodeling to maintain epithelial integrity and barrier function	103
Reticulons promote formation of ER-derived double-membrane vesicles that facilitate SARS-CoV-2 replication	96
Homocysteine disrupts lysosomal function by V-ATPase inhibition	96
VPS13B is localized at the interface between Golgi cisternae and is a functional partner of FAM177A1	86
Edge-vertex flow enables rapid adhesion reinforcement under tension	84
Cholesterol depletion activates trafficking-coupled sphingolipid synthesis	83
Kinetochores grip microtubules with directionally asymmetric strength	74
PI(3)P regulates mitochondrial dynamics through FGD-dependent actin organization	69
Distinct TRAPP complexes activate Ypt/Rab GTPases in secretion and autophagy	67
Diverse microtubule-binding repeats regulate TPX2 activities at distinct locations within the spindle	63
Tld1 is a regulator of triglyceride lipolysis that demarcates a lipid droplet subpopulation	62
GxcM-Fbp17/RacC-WASP signaling regulates polarized cortex assembly in migrating cells via Arp2/3	61
A function of TPL/TBL1-type corepressors is to nucleate the assembly of the preinitiation complex	60
A conserved role for centriolar satellites in translation of centrosomal and ciliary proteins	59
ESCRT-I and PTPN23 mediate microautophagy of ubiquitylated tau aggregates	58
Sugar-free synapses run on mitochondrial Sirtuin 3	57
The PAX3-FOXO1 fusion gene reduces cell–ECM interactions and TGFβ signaling in rhabdomyosarcoma	57

Lipid droplets: Open questions and conceptual advances around a unique organelle	57
Distinct roles of two homologous kinesins in mammalian motile cilia	55
Stress granules and mTOR are regulated by membrane atg8ylation during lysosomal damage	55
Mechanisms of genome instability from cellular folate stress	54
RIM and MUNC13 membrane–binding domains are essential for neuropeptide secretion	52
Phollow the phosphoinositol: Actin dynamics at the B cell immune synapse	52
PtdIns(3,4)P2, Lamellipodin, and VASP coordinate actin dynamics during phagocytosis in macrophages	50
Rab GTPases as “eat me” signals for selective autophagy	50
Liquid–liquid phase separation facilitates the biogenesis of secretory storage granules	50
C17orf80 binds the mitochondrial genome to promote its replication	49
Bill Weis (1959–2023): Pioneering structural biologist and biochemist who revolutionized our understanding of cell adhesion and Wnt signaling	49
Centriole structural integrity defects are a crucial feature of hydrolethalus syndrome	47
TIMP-1 is a novel ligand of Amyloid Precursor Protein and triggers a proinflammatory phenotype in human monocytes	47
The phospholipids cardiolipin and phosphatidylethanolamine differentially regulate MDC biogenesis	46
SARS-CoV-2 specific adaptations in N protein inhibit NF-κB activation and alter pathogenesis	46
Taperin bundles F-actin at stereocilia pivot points enabling optimal lifelong mechanosensitivity	46
A gene duplication of a septin reveals a developmentally regulated filament length control mechanism	45
Migrasomes: Biogenesis, physiological roles, and therapeutic potentials	45
Crosstalk within and beyond the Polycomb repressive system	45
uPA-mediated remodeling of CCL21 gradients regulates lymphatic migration of dendritic cells	44
Stu2 performs an essential kinetochore function independent of its microtubule polymerase activity	44
Cdc5-mediated Ulp2 phosphorylation controls the timing of polySUMOylation during the cell cycle	43
Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking	43
Allocation of resources among multiple daughter cells	43
Mitochondria limit coenzyme Q export under cholesterol biosynthetic stress	42
Migratory autolysosome disposal mitigates lysosome damage	42
FGFR2 residence in primary cilia is necessary for epithelial cell signaling	42
Disruption of macrophage cell volume drives inflammatory responses and type I interferon signaling	41
Cryo-EM reveals how the mastigoneme assembles and responds to environmental signal changes	41
Tubulin regulates stability and localization of STMN2 by binding preferentially to its soluble form	40
Mechanisms of nuclear segregation in a multinucleate multibudding yeast	40
ARHGEF17/TEM4 regulates the cell cycle through control of G1 progression	39
Organization of a cytoskeletal superstructure in the apical domain of intestinal tuft cells	39
A Rab1 interactome illuminates a dual role in autophagy and membrane trafficking	39
Separating chromosomes, one way or another	39
ER-derived caveolin-coated vesicles transport newly synthesized cholesterol to the plasma membrane	39
Force tuning through regulation of clathrin-dependent integrin endocytosis	38
Refining S-acylation: Structure, regulation, dynamics, and therapeutic implications	38
Eps15/Pan1p is a master regulator of the late stages of the endocytic pathway	38
Vav independently regulates synaptic growth and plasticity through distinct actin-based processes	38
DeepContact: High-throughput quantification of membrane contact sites based on electron microscopy imaging	37
Human atlastin-3 is a constitutive ER membrane fusion catalyst	37
Genome-wide conditional degron libraries for functional genomics	37
Spatially coordinated cell cycle activity and motility govern bifurcation of mammary branches	36
Perinuclear non-centrosomal microtubules direct nuclei dispersion during epithelial morphogenesis	36
The IQGAP scaffolds: Critical nodes bridging receptor activation to cellular signaling	36
Phosphatidylserine exposure and annexin A5 weaken the actin cortex in osteoclast fusion	36
A complex of the lipid transport ER proteins TMEM24 and C2CD2 with band 4.1 at cell–cell contacts	35
Newborn daughters get a fresh start through PI(3,5)P2-mediated vacuolar acidification	35
Competition for calnexin binding regulates secretion and turnover of misfolded GPI-anchored proteins	35

StableMARK-decorated microtubules in cells have expanded lattices	34
Paxillin phase separation promotes focal adhesion assembly and integrin signaling	34
Microtubule-binding domains in Katanin p80 subunit are essential for severing activity in C. elegans	34
Septin-mediated RhoA activation engages the exocyst complex to recruit the cilium transition zone	34
Repression of CENP-A assembly in metaphase requires HJURP phosphorylation and inhibition by M18BP1	34
Intercellular mitochondrial transfer and trans-mitophagy in response to protein import dysfunction	34
Understanding microtubule dynamics: The synergy of technology, theory, and experiment	34
B4GALT1 and Wntless collaborate to block LRP5/6 translocation from Golgi to cell surface	33
Tunneling nanotubes and cytonemes in cancer and development	33
A biotin-HaloTag ligand enables efficient affinity capture of protein variants from live cells	33
Endosomal recycling defects link Huntington’s disease with McLeod syndrome	32
A covalently linked probe to monitor local membrane properties surrounding plasma membrane proteins	32
A membrane-sensing mechanism links lipid metabolism to protein degradation at the nuclear envelope	32
Correction: Netrins and neogenin promote myotube formation	32
Autolysosomal exocytosis of lipids protect neurons from ferroptosis	31
Hyperstabilization of T cell microvilli contacts by chimeric antigen receptors	31
A fluorogenic complementation tool kit for interrogating lipid droplet–organelle interaction	31
T cells use focal adhesions to pull themselves through confined environments	31
Satellite view: Dissection of PCM1 assembly processes reveals centriolar satellite structures	31
The low-density lipoprotein receptor–mTORC1 axis coordinates CD8+ T cell activation	31
A Lifeact-EGFP quail for studying actin dynamics in vivo	30
ER-localized Shr3 is a selective co-translational folding chaperone necessary for amino acid permease biogenesis	30
LC3B is a cofactor for LMX1B-mediated transcription of autophagy genes in dopaminergic neurons	30
The cytoskeleton contributes to abnormal genome–lamina interactions in LMNA -deficient cardiomyocytes	30
Axonal transport of autophagosomes is regulated by dynein activators JIP3/JIP4 and ARF/RAB GTPases	30
The role of midbody-associated mRNAs in regulating abscission	30
ATG9A facilitates the closure of mammalian autophagosomes	29
The cell biologist’s guide to detecting and modulating membrane phospholipids	29
Spindle morphology changes between meiosis and mitosis driven by CK2 regulation of the Ran pathway	29
Ultrastructure of dopaminergic varicosities revealed by cryo-correlative light and electron microscopy	29
Neutrophil serine proteases degrade endothelial cortactin and promote extravasation	29
Irg1l regulates neuromast size via metabolic reprogramming to promote supporting cell proliferation	29
Centralspindlin proteins Pavarotti and Tumbleweed along with WASH regulate nuclear envelope budding	28
Mitochondrial fission controls astrocyte morphogenesis and organization in the cortex	28
RCC1 depletion drives protein transport defects and rupture in micronuclei	28
Mitochondria–ER–PM contacts regulate mitochondrial division and PI(4)P distribution	28
RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursors	28
Reticular adhesions are assembled at flat clathrin lattices and opposed by active integrin α5β1	28
SUMOylation at the inner nuclear membrane facilitates nuclear envelope biogenesis during mitosis	28
Visualizing ER-phagy and ER architecture in vivo	27
Composition and organization of kinetochores show plasticity in apicomplexan chromosome segregation	27
Mechanical control of osteoclast fusion by membrane-cortex attachment and BAR proteins	27
Light-based modulation of astrocytic calcium for regulation of organelle dynamics and morphogenesis	27
Faa1 membrane binding drives positive feedback in autophagosome biogenesis via fatty acid activation	27
How do trypanosome IFT trains choose special tracks?	27
A proteome-wide yeast degron collection for the dynamic study of protein function	27
Nodal modulator (NOMO) is a force-bearing transmembrane protein required for muscle differentiation	27
Kinesin-1 autoinhibition facilitates the initiation of dynein cargo transport	27
Neuroligin-2 is ubiquitinated by Nedd4l to control developmental astrocyte morphogenesis	27
Polyploidy reprograms epithelial cells for motility and phagocytosis via stress signaling	26
Fusion pore dynamics of large secretory vesicles define a distinct mechanism of exocytosis	26
Centrosome age breaks spindle size symmetry even in cells thought to divide symmetrically	26
Extracellular vesicles adhere to cells primarily by interactions of integrins and GM1 with laminin	26
Plasma membrane-to-lysosome FGR signaling regulates endocytosis-associated lysosome homeostasis	26
Super-resolution microscopy: Insights into mitochondria–lysosome crosstalk in health and disease	26
GCL pruning of PIP3 establishes the soma-germline boundary	26
Lipid packing and local geometry influence septin curvature sensing	26
Endothelial depletion of Atg7 triggers astrocyte–microvascular disassociation at blood–brain barrier	26
Not just protons: Chloride also activates lysosomal acidic hydrolases	26
A farnesyl-dependent structural role for CENP-E in expansion of the fibrous corona	25
The bioenergetics of nucleocytoplasmic transport	25
Synaptotagmin-1 in phase: Condensate biology reveals new insights into the synaptic calcium sensor	25
OMA1 clears traffic jam in TOM tunnel in mammals	25
Nuclear pore complexes mediate subtelomeric gene silencing by regulating PCNA levels on chromatin	25
A plant-specific bridging adaptor for amphisome biogenesis	24
Phosphoproteomic identification of Mos–MAPK targets in meiotic cell cycle and asymmetric oocyte divisions	24
Structural characterization and inhibition of the interaction between ch-TOG and TACC3	24
Controlling scissors during DNA repair of UV light–induced damage	24
Lactylation stabilizes TFEB to elevate autophagy and lysosomal activity	24
Making lipids very unhappy to discover how they bind to proteins	24
CDR2 is a dynein adaptor recruited by kinectin to regulate ER sheet organization	24
Prolonged depletion of profilin 1 or F-actin causes an adaptive response in microtubules	24
Meiotic nuclear pore complex remodeling provides key insights into nuclear basket organization	24
Periodic changes of cyclin D1 mRNA stability are regulated by PC4 modifications in the cell cycle	24
Ist2 is a phospholipid scramblase that links lipid transport at the ER to organelle homeostasis	24
The p97 ATPase and its adaptor UBXD8 maintain peroxisome pools by preventing pexophagy	24
Tailored assemblies of COPII proteins in secretion	24
Inhibition of endolysosome fusion increases exosome secretion	24
Skin without fibroblasts: Rethinking epidermal–dermal dependence	23
Tension-induced suppression of allosteric conformational changes coordinates kinesin-1 stepping	23

Integration of cell wall synthesis and chromosome segregation during cell division in Caulobacter	23
Binucleated human hepatocytes arise through late cytokinetic regression during endomitosis M phase	23
An interaction between β′-COP and the ArfGAP, Glo3, maintains post-Golgi cargo recycling	23
Scrib organizes cortical actomyosin clusters to maintain adherens junctions and angiogenic sprouting	23
JIP4 and RILPL1 utilize opposing motor force to dynamically regulate lysosomal tubulation	23
Splicing under stress: A matter of time and place	23
Cell polarity changes in cancer initiation and progression	23
Rickettsia parkeri forms extensive, stable contacts with the rough endoplasmic reticulum	23
The autophagy protein ATG-9 regulates lysosome function and integrity	23
Actin arginylation alters myosin engagement and F-actin patterning despite structural conservation	23
NuMA is a mitotic adaptor protein that activates dynein and connects it to microtubule minus ends	23
Receptor-mediated Golgi retention of Fam20 kinases tunes secretome phosphorylation during lactation	23
Mechanometabolism of cell adhesion: Vinculin regulates bioenergetics via RhoA-ROCK	23
α-Catenin force-sensitive binding and sequestration of LZTS2 leads to cytokinesis failure	22
A specialized tyrosine-based endocytosis signal in MR1 controls antigen presentation to MAIT cells	22
Bridging condensins mediate compaction of mitotic chromosomes	22
PI(4,5)P2 diffuses freely in the plasma membrane even within high-density effector protein complexes	22
Seipin: A central lipid rheostat	22
Eosinophils promote a second wave of postnatal smooth muscle differentiation in intestinal villi	22
ARHGAP17 regulates the spatiotemporal activity of Cdc42 at invadopodia	22
Tubulin isotypes contribute opposing properties to balance anaphase spindle morphogenesis	22
p62 sorts Lupus La and selected microRNAs into breast cancer-derived exosomes	22
LYSMD proteins promote activation of Rab32-family GTPases for lysosome-related organelle biogenesis	22
The minus-end depolymerase KIF2A drives flux-like treadmilling of γTuRC-uncapped microtubules	22
NME3 binds to phosphatidic acid and mediates PLD6-induced mitochondrial tethering	21
PEX14 acts as a molecular link between optineurin and the autophagic machinery to induce pexophagy	21
Determining how many cells to average for statistical testing of microscopy experiments	21
Glucose starvation signaling via nucleus-vacuole junction remodeling controls ergosterol synthesis	21
E- and N-cadherin drive hepatic polarity and lumen elongation via opposing effects on RhoA activity	21
Murine glial protrusion transcripts predict localized Drosophila glial mRNAs involved in plasticity	21
Plasticity of mitotic cyclins in promoting the G2–M transition	21
Painting lysosomes to study organelle heterogeneity	21
Long live lamins	21
Inwardly rectifying potassium channels promote directional sensing during neutrophil chemotaxis	21
Directed stochasticity: Building biomolecular condensates in the right place	21
The emerging roles of non-canonical ubiquitination in proteostasis and beyond	21
ER as master regulator of membrane trafficking and organelle function	21
Fission-independent compartmentalization of mitochondria during budding yeast cell division	21
Ca2+ binding to Esyt modulates membrane contact site density in Drosophila photoreceptors	21
Nuclear poly-glutamine aggregates rupture the nuclear envelope and hinder its repair	21
APOE traffics to astrocyte lipid droplets and modulates triglyceride saturation and droplet size	21
Pexophagy meets physiology	20
Centrosome-organized plasma membrane infoldings linked to growth of a cortical actin domain	20
Claudin 7 suppresses invasion and metastasis through repression of a smooth muscle actin program	20
CLASPs stabilize the pre-catastrophe intermediate state between microtubule growth and shrinkage	20
Landscape expansion microscopy reveals interactions between membrane and phase-separated organelles	20
Liquid–liquid phase separation mediates the formation of herpesvirus assembly compartments	20
RFWD3 promotes ZRANB3 recruitment to regulate the remodeling of stalled replication forks	20
p24 family Tango(1) at the endoplasmic reticulum exit site to organize cargo exit	20
RAB-10 cooperates with EHBP-1 to capture vesicular carriers during post-Golgi exocytic trafficking	20
Centriolar satellites assemble via a hierarchical pathway driven by PCM1 multimerization	20
Early proteostasis of caveolins synchronizes trafficking, degradation, and oligomerization to prevent toxic aggregation	20
Vacuolar pH regulates clathrin-mediated endocytosis through TORC1 signaling during replicative aging	20
Balancing cell polarity PARts through dephosphorylation	20
An inducible multiciliated cell line resolves proteome dynamics and identifies CDK7 as a conserved regulator	20
The Ndc80-Cdt1-Ska1 complex is a central processive kinetochore–microtubule coupling unit	20
Deep learning techniques and mathematical modeling allow 3D analysis of mitotic spindle dynamics	20
FUT8-mediated core fucosylation stabilizes TMEM67 to promote ciliogenesis	20
WAVE complex forms linear arrays at negative membrane curvature to instruct lamellipodia formation	20
VASH1–SVBP and VASH2–SVBP generate different detyrosination profiles on microtubules	20
Structural response of microtubule and actin cytoskeletons to direct intracellular load	20
A collagen IV fluorophore knock-in toolkit reveals trimer diversity in C. elegans basement membranes	19
Zn2+ decoration of microtubules arrests axonal transport and displaces tau, doublecortin, and MAP2C	19
Nanoscale architect: Illuminating the key organizer of the fruit fly’s sensory world	19
RTN3 and RTN4: Architects of SARS-CoV-2 replication organelles	19
LGI3/2–ADAM23 interactions cluster Kv1 channels in myelinated axons to regulate refractory period	19
Oiling the wheels of nuclear division: SUMOylation regulates the expansion of the mitotic nuclear membrane	19
Tepsin and AP4 mediate transport from the trans-Golgi to the plant-like vacuole in toxoplasma	19
SIR telomere silencing depends on nuclear envelope lipids and modulates sensitivity to a lysolipid	19
AMPK regulates phagophore-to-autophagosome maturation	19
Unveiling the TRAPP: The role of plant TRAPPII in adaptive growth decisions	19
One step 4× and 12× 3D-ExM enables robust super-resolution microscopy of nanoscale cellular structures	19
Protein Kinase C promotes peroxisome biogenesis and peroxisome–endoplasmic reticulum interaction	19
High-content phenotyping reveals Golgi dynamics and their role in cell cycle regulation	19
Vinculin is required for interkinetic nuclear migration (INM) and cell cycle progression	19
Molding a PI(3,5)P2 biosensor	19
ARF3 weights the balance for prostate cancer metastasis	19
Expanded directly binds conserved regions of Fat to restrain growth via the Hippo pathway	19
The septin cytoskeleton: Heteromer composition defines filament function	18
Regulation of Cajal bodies: Unexpected connection to 60S ribosomes	18
Small lipid droplets are rigid enough to indent a nucleus, dilute the lamina, and cause rupture	18
Ubiquitin chain variability directs substrates of the Tul1 ubiquitin ligase complex to different degradation pathways	18
Correction: Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis	18
Kinetochores get a grip!	18
Fascin-induced bundling protects actin filaments from disassembly by cofilin	18
Postsynaptic BMP signaling regulates myonuclear properties in Drosophila larval muscles	18
Cargo adaptors use a handhold mechanism to engage with myosin V for organelle transport	18
A second chance at yeast early endosomes	18
A substrate-interacting region of Parkin directs ubiquitination of the mitochondrial GTPase Miro1	18
Chromosome segregation synchrony in S. pombe is noise limited and arises without positive feedback	18
Synaptotagmin-1 undergoes phase separation to regulate its calcium-sensitive oligomerization	18
Chasing the right tail: How the ER membrane complex recognizes its substrates	18
ISWI chromatin remodeling complexes recruit NSD2 and H3K36me2 in pericentromeric heterochromatin	18
A pyrophosphatase that regulates lipid precursors of N-glycosylation	18
Successful 3D imaging of cleared biological samples with light sheet fluorescence microscopy	18