Journal of Cell Biology

Papers
(The median citation count of Journal of Cell Biology is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)
ArticleCitations
LNCcation: lncRNA localization and function578
SuperPlots: Communicating reproducibility and variability in cell biology392
Autophagosome biogenesis: From membrane growth to closure176
Mitochondrial regulation of ferroptosis175
Lysosome biogenesis: Regulation and functions143
The cell biology of synapse formation131
Mitophagy pathways in health and disease117
Cryo-EM reconstruction of a VPS13 fragment reveals a long groove to channel lipids between membranes111
Critical role of mitochondrial ubiquitination and the OPTN–ATG9A axis in mitophagy107
SARM1 acts downstream of neuroinflammatory and necroptotic signaling to induce axon degeneration97
Liquid–liquid phase separation in autophagy94
Paradoxical roles of caspase-3 in regulating cell survival, proliferation, and tumorigenesis94
TMEM41B and VMP1 are scramblases and regulate the distribution of cholesterol and phosphatidylserine87
VPS13D bridges the ER to mitochondria and peroxisomes via Miro85
STING induces LC3B lipidation onto single-membrane vesicles via the V-ATPase and ATG16L1-WD40 domain85
The RNA binding protein FMR1 controls selective exosomal miRNA cargo loading during inflammation82
FUS-dependent liquid–liquid phase separation is important for DNA repair initiation82
Lipid droplets in the nervous system80
Cancer cells educate natural killer cells to a metastasis-promoting cell state79
Mechanisms of nonvesicular lipid transport79
The NLRP3–inflammasome as a sensor of organelle dysfunction77
The cell biology of Parkinson’s disease76
Mitochondria as intracellular signaling platforms in health and disease70
CDK4/6 regulate lysosome biogenesis through TFEB/TFE369
Recognition of RNA by the S9.6 antibody creates pervasive artifacts when imaging RNA:DNA hybrids68
Seipin and Nem1 establish discrete ER subdomains to initiate yeast lipid droplet biogenesis68
Microtubules control cellular shape and coherence in amoeboid migrating cells66
Sequential dynein effectors regulate axonal autophagosome motility in a maturation-dependent pathway63
PD-1 and BTLA regulate T cell signaling differentially and only partially through SHP1 and SHP261
Who’s in control? Principles of Rab GTPase activation in endolysosomal membrane trafficking and beyond61
3D FIB-SEM reconstruction of microtubule–organelle interaction in whole primary mouse β cells60
Pathogenic mutations in the kinesin-3 motor KIF1A diminish force generation and movement through allosteric mechanisms59
COPII collar defines the boundary between ER and ER exit site and does not coat cargo containers58
Phospholipid ebb and flow makes mitochondria go58
Phase separation of Axin organizes the β-catenin destruction complex57
The proline-rich domain promotes Tau liquid–liquid phase separation in cells56
Ribosome heterogeneity in stem cells and development56
ULK complex organization in autophagy by a C-shaped FIP200 N-terminal domain dimer56
Evolving models for assembling and shaping clathrin-coated pits56
Similarities and interplay between senescent cells and macrophages55
A PI3K-WIPI2 positive feedback loop allosterically activates LC3 lipidation in autophagy55
High-fidelity reconstitution of stress granules and nucleoli in mammalian cellular lysate54
Endosomal escape of delivered mRNA from endosomal recycling tubules visualized at the nanoscale53
Neutral lipids regulate amphipathic helix affinity for model lipid droplets53
ECM deposition is driven by caveolin-1–dependent regulation of exosomal biogenesis and cargo sorting52
Ubiquitin chains earmark GPCRs for BBSome-mediated removal from cilia52
Ubiquitin links smoothened to intraflagellar transport to regulate Hedgehog signaling50
High-content imaging-based pooled CRISPR screens in mammalian cells49
Time-resolved proteomics profiling of the ciliary Hedgehog response49
V-ATPase is a universal regulator of LC3-associated phagocytosis and non-canonical autophagy49
Secretory autophagy maintains proteostasis upon lysosome inhibition49
Role of the early secretory pathway in SARS-CoV-2 infection48
Topological features of integrin adhesion complexes revealed by multiplexed proximity biotinylation47
VPS13D promotes peroxisome biogenesis47
The long journey to bring a Myc inhibitor to the clinic46
Torsin ATPase deficiency leads to defects in nuclear pore biogenesis and sequestration of MLF246
Nuclear lipid droplets form in the inner nuclear membrane in a seipin-independent manner46
Regulated lipid synthesis and LEM2/CHMP7 jointly control nuclear envelope closure45
TORC1 inactivation stimulates autophagy of nucleoporin and nuclear pore complexes45
Radial contractility of actomyosin rings facilitates axonal trafficking and structural stability45
Image-based pooled whole-genome CRISPRi screening for subcellular phenotypes44
Transmembrane phospholipid translocation mediated by Atg9 is involved in autophagosome formation44
Stress sensor Ire1 deploys a divergent transcriptional program in response to lipid bilayer stress43
Adherens junction regulates cryptic lamellipodia formation for epithelial cell migration43
PINK1 drives production of mtDNA-containing extracellular vesicles to promote invasiveness42
Identification of novel synaptonemal complex components in C. elegans42
CRISPR-Cas12a–assisted PCR tagging of mammalian genes41
Cytoskeletal organization of axons in vertebrates and invertebrates41
Protrudin-mediated ER–endosome contact sites promote MT1-MMP exocytosis and cell invasion41
Sarm1 activation produces cADPR to increase intra-axonal Ca++ and promote axon degeneration in PIPN41
Polo-like kinase 1 independently controls microtubule-nucleating capacity and size of the centrosome39
Interferon-stimulated gene 15 accelerates replication fork progression inducing chromosomal breakage39
Mitochondrial fragmentation enables localized signaling required for cell repair39
Coupling of translation quality control and mRNA targeting to stress granules39
mTORC1 activity is supported by spatial association with focal adhesions38
Synaptic activity controls autophagic vacuole motility and function in dendrites38
Direct binding of ESCRT protein Chm7 to phosphatidic acid–rich membranes at nuclear envelope herniations38
CDC42EP5/BORG3 modulates SEPT9 to promote actomyosin function, migration, and invasion37
Chlamydomonas PKD2 organizes mastigonemes, hair-like glycoprotein polymers on cilia37
Phagosome resolution regenerates lysosomes and maintains the degradative capacity in phagocytes37
Binding and transport of SFPQ-RNA granules by KIF5A/KLC1 motors promotes axon survival36
Catalytically inactive, purified RNase H1: A specific and sensitive probe for RNA–DNA hybrid imaging36
Analysis of copy number alterations reveals the lncRNA ALAL-1 as a regulator of lung cancer immune evasion35
High-speed single-molecule imaging reveals signal transduction by induced transbilayer raft phases35
Computational analyses reveal spatial relationships between nuclear pore complexes and specific lamins35
SAMM50 acts with p62 in piecemeal basal- and OXPHOS-induced mitophagy of SAM and MICOS components35
Caveolin-1 and cavin1 act synergistically to generate a unique lipid environment in caveolae35
FIT2 is an acyl–coenzyme A diphosphatase crucial for endoplasmic reticulum homeostasis35
Structural and biochemical insights into lipid transport by VPS13 proteins35
Rapid degradation of GRASP55 and GRASP65 reveals their immediate impact on the Golgi structure34
DOT1L modulates the senescence-associated secretory phenotype through epigenetic regulation of IL1A34
Regulation of Golgi turnover by CALCOCO1-mediated selective autophagy34
Cyclin B1-Cdk1 facilitates MAD1 release from the nuclear pore to ensure a robust spindle checkpoint34
Mechanosensitive calcium flashes promote sustained RhoA activation during tight junction remodeling34
MICAL2 enhances branched actin network disassembly by oxidizing Arp3B-containing Arp2/3 complexes33
Tyramide signal amplification mass spectrometry (TSA-MS) ratio identifies nuclear speckle proteins33
Telomerase treatment prevents lung profibrotic pathologies associated with physiological aging33
The WAVE complex associates with sites of saddle membrane curvature33
ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling32
XMAP215 promotes microtubule catastrophe by disrupting the growing microtubule end32
The modified mitochondrial outer membrane carrier MTCH2 links mitochondrial fusion to lipogenesis32
Mitochondrial translation and dynamics synergistically extend lifespan in C. elegans through HLH-3032
Nesprins are mechanotransducers that discriminate epithelial–mesenchymal transition programs32
VE-cadherin endocytosis controls vascular integrity and patterning during development32
HDAC6 regulates microtubule stability and clustering of AChRs at neuromuscular junctions32
A cryo-ET survey of microtubules and intracellular compartments in mammalian axons31
The cell biology of inflammation: From common traits to remarkable immunological adaptations31
Ubiquitin ligase MARCH5 localizes to peroxisomes to regulate pexophagy31
Long-lived mitochondrial cristae proteins in mouse heart and brain31
Sterol biosensor reveals LAM-family Ltc1-dependent sterol flow to endosomes upon Arp2/3 inhibition31
PI4P/PS countertransport by ORP10 at ER–endosome membrane contact sites regulates endosome fission31
FHL2 anchors mitochondria to actin and adapts mitochondrial dynamics to glucose supply30
PLCγ1 promotes phase separation of T cell signaling components30
Afadin regulates actomyosin organization through αE-catenin at adherens junctions30
Intracellular wetting mediates contacts between liquid compartments and membrane-bound organelles30
Prolonged mitosis results in structurally aberrant and over-elongated centrioles30
Quantitative correlative microscopy reveals the ultrastructural distribution of endogenous endosomal proteins30
Alternative splicing of clathrin heavy chain contributes to the switch from coated pits to plaques30
High-precision targeting workflow for volume electron microscopy30
A non-canonical Hedgehog pathway initiates ciliogenesis and autophagy30
Fusion of lysosomes to plasma membrane initiates radiation-induced apoptosis30
ER as master regulator of membrane trafficking and organelle function30
ER–mitochondria contacts promote mitochondrial-derived compartment biogenesis29
Mitochondrial DNA segregation and replication restrict the transmission of detrimental mutation29
Capture and delivery of tail-anchored proteins to the endoplasmic reticulum29
In situ cryo-electron tomography reveals filamentous actin within the microtubule lumen29
CRISPR screens for lipid regulators reveal a role for ER-bound SNX13 in lysosomal cholesterol export29
Lipid droplets and the host–pathogen dynamic: FATal attraction?29
Fission yeast Pak1 phosphorylates anillin-like Mid1 for spatial control of cytokinesis29
The Rab7 effector WDR91 promotes autophagy-lysosome degradation in neurons by regulating lysosome fusion29
Phosphorylation of SNX27 by MAPK11/14 links cellular stress–signaling pathways with endocytic recycling29
Label-retention expansion microscopy29
GTP-dependent formation of straight tubulin oligomers leads to microtubule nucleation29
ANO5 ensures trafficking of annexins in wounded myofibers28
FXR1 splicing is important for muscle development and biomolecular condensates in muscle cells28
FMNL2 regulates dynamics of fascin in filopodia28
Vps13-like proteins provide phosphatidylethanolamine for GPI anchor synthesis in the ER28
Wapl releases Scc1-cohesin and regulates chromosome structure and segregation in mouse oocytes28
USP19 promotes hypoxia-induced mitochondrial division via FUNDC1 at ER-mitochondria contact sites28
Multivalent weak interactions between assembly units drive synaptonemal complex formation28
Centriole-independent mitotic spindle assembly relies on the PCNT–CDK5RAP2 pericentriolar matrix27
A guide to membrane atg8ylation and autophagy with reflections on immunity27
Cargo crowding contributes to sorting stringency in COPII vesicles27
mRNA localization mediates maturation of cytoplasmic cilia in Drosophila spermatogenesis27
CENP-F stabilizes kinetochore-microtubule attachments and limits dynein stripping of corona cargoes27
Kinetochore phosphatases suppress autonomous Polo-like kinase 1 activity to control the mitotic checkpoint27
Factors promoting nuclear envelope assembly independent of the canonical ESCRT pathway27
Evidence for anaphase pulling forces during C. elegans meiosis27
A polybasic domain in aPKC mediates Par6-dependent control of membrane targeting and kinase activity27
Branched actin networks are assembled on microtubules by adenomatous polyposis coli for targeted membrane protrusion27
CENP-A overexpression promotes aneuploidy with karyotypic heterogeneity26
WASP integrates substrate topology and cell polarity to guide neutrophil migration26
Angulin-1 seals tricellular contacts independently of tricellulin and claudins26
A ciliopathy complex builds distal appendages to initiate ciliogenesis26
NUCKS1 promotes RAD54 activity in homologous recombination DNA repair26
Induction of spontaneous human neocentromere formation and long-term maturation26
A modified lysosomal organelle mediates nonlytic egress of reovirus26
Cnm1 mediates nucleus–mitochondria contact site formation in response to phospholipid levels26
An antibody toolbox to track complex I assembly defines AIF’s mitochondrial function26
Kinetochore-bound Mps1 regulates kinetochore–microtubule attachments via Ndc80 phosphorylation26
Atg39 links and deforms the outer and inner nuclear membranes in selective autophagy of the nucleus25
A septin GTPase scaffold of dynein–dynactin motors triggers retrograde lysosome transport25
Subcellular localization of the J-protein Sis1 regulates the heat shock response25
CDKD-dependent activation of CDKA;1 controls microtubule dynamics and cytokinesis during meiosis25
Asymmetric assembly of centromeres epigenetically regulates stem cell fate25
RIM-binding protein couples synaptic vesicle recruitment to release sites25
Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination25
Dendritic cell actin dynamics control contact duration and priming efficiency at the immunological synapse25
GOLPH3 and GOLPH3L are broad-spectrum COPI adaptors for sorting into intra-Golgi transport vesicles25
p53 deficiency triggers dysregulation of diverse cellular processes in physiological oxygen25
Structural insights into G domain dimerization and pathogenic mutation of OPA125
Plectin-mediated cytoskeletal crosstalk controls cell tension and cohesion in epithelial sheets25
Optogenetic activators of apoptosis, necroptosis, and pyroptosis25
Deorphanizing FAM19A proteins as pan-neurexin ligands with an unusual biosynthetic binding mechanism25
The UPRmt preserves mitochondrial import to extend lifespan25
Vps13D functions in a Pink1-dependent and Parkin-independent mitophagy pathway25
Atlastin 2/3 regulate ER targeting of the ULK1 complex to initiate autophagy24
Opposing functions for retromer and Rab11 in extracellular vesicle traffic at presynaptic terminals24
LUZP1 and the tumor suppressor EPLIN modulate actin stability to restrict primary cilia formation24
Notch2 complements Notch1 to mediate inductive signaling that initiates early T cell development24
Nano-scale resolution of native retinal rod disk membranes reveals differences in lipid composition24
Conserved actin machinery drives microtubule-independent motility and phagocytosis in Naegleria24
NBR1: The archetypal selective autophagy receptor24
Cell division requires RNA eviction from condensing chromosomes24
C-ferroptosis is an iron-dependent form of regulated cell death in cyanobacteria24
VMP1 and TMEM41B are essential for DMV formation during β-coronavirus infection24
Effector-mediated ERM activation locally inhibits RhoA activity to shape the apical cell domain23
Specific KIF1A–adaptor interactions control selective cargo recognition23
Twinfilin bypasses assembly conditions and actin filament aging to drive barbed end depolymerization23
Regulating peroxisome–ER contacts via the ACBD5-VAPB tether by FFAT motif phosphorylation and GSK3β23
Biochemical reconstitutions reveal principles of human γ-TuRC assembly and function23
Object detection networks and augmented reality for cellular detection in fluorescence microscopy23
Molecular basis of MKLP2-dependent Aurora B transport from chromatin to the anaphase central spindle23
Stable inheritance of CENP-A chromatin: Inner strength versus dynamic control23
Consensus nomenclature for dyneins and associated assembly factors23
The +TIP Navigator-1 is an actin–microtubule crosslinker that regulates axonal growth cone motility23
TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination23
MICOS subcomplexes assemble independently on the mitochondrial inner membrane in proximity to ER contact sites23
Dual spindles assemble in bovine zygotes despite the presence of paternal centrosomes23
Oocytes mount a noncanonical DNA damage response involving APC-Cdh1–mediated proteolysis22
Quality control of 40S ribosome head assembly ensures scanning competence22
Live imaging of transcription sites using an elongating RNA polymerase II–specific probe22
Shared and specific functions of Arfs 1–5 at the Golgi revealed by systematic knockouts22
An asymmetric junctional mechanoresponse coordinates mitotic rounding with epithelial integrity22
Teasing out function from morphology: Similarities between primary cilia and immune synapses22
E3 ubiquitin ligase Wwp1 regulates ciliary dynamics of the Hedgehog receptor Smoothened22
An APEX2 proximity ligation method for mapping interactions with the nuclear lamina22
ORP5 and ORP8 orchestrate lipid droplet biogenesis and maintenance at ER–mitochondria contact sites22
Plk4 triggers autonomous de novo centriole biogenesis and maturation22
ZNF416 is a pivotal transcriptional regulator of fibroblast mechanoactivation22
Nucleobindin-1 regulates ECM degradation by promoting intra-Golgi trafficking of MMPs22
Intersection of TKS5 and FGD1/CDC42 signaling cascades directs the formation of invadopodia21
Regulation of membrane NMDA receptors by dynamics and protein interactions21
Confounding factors from inducible systems for spatiotemporal gene expression regulation21
Autophagy facilitates mitochondrial rebuilding after acute heat stress via a DRP-1–dependent process21
SARS-CoV-2 ORF10 impairs cilia by enhancing CUL2ZYG11B activity21
NCOA4 drives ferritin phase separation to facilitate macroferritinophagy and microferritinophagy21
Phase separation and toxicity of C9orf72 poly(PR) depends on alternate distribution of arginine21
ATG9 vesicles comprise the seed membrane of mammalian autophagosomes21
Cell migration orchestrates migrasome formation by shaping retraction fibers21
A mitochondrial contribution to anti-inflammatory shear stress signaling in vascular endothelial cells21
Tension promotes kinetochore–microtubule release by Aurora B kinase20
Mechanical competition alters the cellular interpretation of an endogenous genetic program20
ESCRT, not intralumenal fragments, sorts ubiquitinated vacuole membrane proteins for degradation20
Centriole and PCM cooperatively recruit CEP192 to spindle poles to promote bipolar spindle assembly20
c entrocortin RNA localization to centrosomes is regulated by FMRP and facilitates error-free mitosis20
Extracellular vesicles from neurons promote neural induction of stem cells through cyclin D120
Combinatorial multivalent interactions drive cooperative assembly of the COPII coat20
Collective invasion induced by an autocrine purinergic loop through connexin-43 hemichannels20
Genetically encoded live-cell sensor for tyrosinated microtubules20
The cell biology of fertilization: Gamete attachment and fusion20
Protein exchange is reduced in calcium-independent epithelial junctions20
Individual kinetochore-fibers locally dissipate force to maintain robust mammalian spindle structure20
The deubiquitylase USP9X controls ribosomal stalling20
The function of GORASPs in Golgi apparatus organization in vivo20
Retinyl esters form lipid droplets independently of triacylglycerol and seipin20
Tricellulin secures the epithelial barrier at tricellular junctions by interacting with actomyosin20
Superresolution characterization of core centriole architecture20
ER membrane contact sites support endosomal small GTPase conversion for exosome secretion20
STING controls energy stress-induced autophagy and energy metabolism via STX1720
Sterol and oxysterol synthases near the ciliary base activate the Hedgehog pathway19
Multivalent interactions make adherens junction–cytoskeletal linkage robust during morphogenesis19
Stochastic combinations of actin regulatory proteins are sufficient to drive filopodia formation19
Liquid–liquid phase separation facilitates the biogenesis of secretory storage granules19
Centromeric transcription maintains centromeric cohesion in human cells19
Stress-responsive regulation of extracellular proteostasis19
WDR60-mediated dynein-2 loading into cilia powers retrograde IFT and transition zone crossing19
The ER cholesterol sensor SCAP promotes CARTS biogenesis at ER–Golgi membrane contact sites19
KIF14 controls ciliogenesis via regulation of Aurora A and is important for Hedgehog signaling19
Novel phospho-switch function of delta-catenin in dendrite development19
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