Journal of Cell Biology

Article	Citations
Sugar-free synapses run on mitochondrial Sirtuin 3	129
Distinct roles of two homologous kinesins in mammalian motile cilia	110
A function of TPL/TBL1-type corepressors is to nucleate the assembly of the preinitiation complex	108
A conserved role for centriolar satellites in translation of centrosomal and ciliary proteins	100
Diverse microtubule-binding repeats regulate TPX2 activities at distinct locations within the spindle	100
A collective strategy to promote the dissemination of single cancer cells	98
GARLH regulates neuroligin preference for excitatory versus inhibitory synapses	97
Cholesterol depletion activates trafficking-coupled sphingolipid synthesis	95
GxcM-Fbp17/RacC-WASP signaling regulates polarized cortex assembly in migrating cells via Arp2/3	91
Homocysteine disrupts lysosomal function by V-ATPase inhibition	90
Distinct TRAPP complexes activate Ypt/Rab GTPases in secretion and autophagy	89
PI(3)P regulates mitochondrial dynamics through FGD-dependent actin organization	84
Developmental pruning of sensory neurites by mechanical tearing in Drosophila	81
Mechanisms of genome instability from cellular folate stress	79
VPS13B is localized at the interface between Golgi cisternae and is a functional partner of FAM177A1	78
Kinetochores grip microtubules with directionally asymmetric strength	77
ESCRT-I and PTPN23 mediate microautophagy of ubiquitylated tau aggregates	73
Reticulons promote formation of ER-derived double-membrane vesicles that facilitate SARS-CoV-2 replication	65
The PAX3-FOXO1 fusion gene reduces cell–ECM interactions and TGFβ signaling in rhabdomyosarcoma	64
Tld1 is a regulator of triglyceride lipolysis that demarcates a lipid droplet subpopulation	62
RIM and MUNC13 membrane–binding domains are essential for neuropeptide secretion	62
Microtubule-driven cell shape changes and actomyosin flow synergize to position the centrosome	61
DBF4, not DRF1, is the crucial regulator of CDC7 kinase at replication forks	60
Stress granules and mTOR are regulated by membrane atg8ylation during lysosomal damage	56
PP6 regulation of Aurora A–TPX2 limits NDC80 phosphorylation and mitotic spindle size	56

Conformational transitions of the Spindly adaptor underlie its interaction with Dynein and Dynactin	55
The α-Catenin mechanosensing M region is required for cell adhesion during tissue morphogenesis	54
Edge-vertex flow enables rapid adhesion reinforcement under tension	54
Lipid droplets: Open questions and conceptual advances around a unique organelle	53
Rab GTPases as “eat me” signals for selective autophagy	52
Bill Weis (1959–2023): Pioneering structural biologist and biochemist who revolutionized our understanding of cell adhesion and Wnt signaling	51
TIMP-1 is a novel ligand of Amyloid Precursor Protein and triggers a proinflammatory phenotype in human monocytes	50
ER-derived caveolin-coated vesicles transport newly synthesized cholesterol to the plasma membrane	49
Fast-evolving cofactors regulate the role of HEATR5 complexes in intra-Golgi trafficking	49
Stu2 performs an essential kinetochore function independent of its microtubule polymerase activity	49
Tubulin regulates stability and localization of STMN2 by binding preferentially to its soluble form	48
FGFR2 residence in primary cilia is necessary for epithelial cell signaling	48
A gene duplication of a septin reveals a developmentally regulated filament length control mechanism	47
uPA-mediated remodeling of CCL21 gradients regulates lymphatic migration of dendritic cells	47
Liquid–liquid phase separation facilitates the biogenesis of secretory storage granules	46
The phospholipids cardiolipin and phosphatidylethanolamine differentially regulate MDC biogenesis	44
A Rab1 interactome illuminates a dual role in autophagy and membrane trafficking	43
Disruption of macrophage cell volume drives inflammatory responses and type I interferon signaling	43
Allocation of resources among multiple daughter cells	42
Centriole structural integrity defects are a crucial feature of hydrolethalus syndrome	42
Mechanisms of nuclear segregation in a multinucleate multibudding yeast	42
Phollow the phosphoinositol: Actin dynamics at the B cell immune synapse	42
Cryo-EM reveals how the mastigoneme assembles and responds to environmental signal changes	42
Crosstalk within and beyond the Polycomb repressive system	41
Taperin bundles F-actin at stereocilia pivot points enabling optimal lifelong mechanosensitivity	41
PtdIns(3,4)P2, Lamellipodin, and VASP coordinate actin dynamics during phagocytosis in macrophages	41
Refining S-acylation: Structure, regulation, dynamics, and therapeutic implications	41
C17orf80 binds the mitochondrial genome to promote its replication	40
ARHGEF17/TEM4 regulates the cell cycle through control of G1 progression	39
Cdc5-mediated Ulp2 phosphorylation controls the timing of polySUMOylation during the cell cycle	39
Migrasomes: Biogenesis, physiological roles, and therapeutic potentials	38
SARS-CoV-2 specific adaptations in N protein inhibit NF-κB activation and alter pathogenesis	38
Separating chromosomes, one way or another	38
Newborn daughters get a fresh start through PI(3,5)P2-mediated vacuolar acidification	37
Microtubule-binding domains in Katanin p80 subunit are essential for severing activity inC. elegans	37
Migratory autolysosome disposal mitigates lysosome damage	37
Spatially coordinated cell cycle activity and motility govern bifurcation of mammary branches	37
Organization of a cytoskeletal superstructure in the apical domain of intestinal tuft cells	37
Perinuclear non-centrosomal microtubules direct nuclei dispersion during epithelial morphogenesis	36
StableMARK-decorated microtubules in cells have expanded lattices	36
B4GALT1 and Wntless collaborate to block LRP5/6 translocation from Golgi to cell surface	36
Vav independently regulates synaptic growth and plasticity through distinct actin-based processes	36
A complex of the lipid transport ER proteins TMEM24 and C2CD2 with band 4.1 at cell–cell contacts	35
Repression of CENP-A assembly in metaphase requires HJURP phosphorylation and inhibition by M18BP1	35
A biotin-HaloTag ligand enables efficient affinity capture of protein variants from live cells	35
DeepContact: High-throughput quantification of membrane contact sites based on electron microscopy imaging	35
Phosphatidylserine exposure and annexin A5 weaken the actin cortex in osteoclast fusion	35
Genome-wide conditional degron libraries for functional genomics	35
Force tuning through regulation of clathrin-dependent integrin endocytosis	35
Competition for calnexin binding regulates secretion and turnover of misfolded GPI-anchored proteins	34

A guide to membrane atg8ylation and autophagy with reflections on immunity	34
Septin-mediated RhoA activation engages the exocyst complex to recruit the cilium transition zone	32
Understanding microtubule dynamics: The synergy of technology, theory, and experiment	32
Paxillin phase separation promotes focal adhesion assembly and integrin signaling	32
Endosomal recycling defects link Huntington’s disease with McLeod syndrome	32
The IQGAP scaffolds: Critical nodes bridging receptor activation to cellular signaling	32
Human atlastin-3 is a constitutive ER membrane fusion catalyst	32
Eps15/Pan1p is a master regulator of the late stages of the endocytic pathway	32
The cytoskeleton contributes to abnormal genome–lamina interactions in LMNA -deficient cardiomyocytes	31
ER-localized Shr3 is a selective co-translational folding chaperone necessary for amino acid permease biogenesis	31
Correction: Netrins and neogenin promote myotube formation	31
Plan your trip before you leave: The neutrophils’ search-and-run journey	31
Spindle morphology changes between meiosis and mitosis driven by CK2 regulation of the Ran pathway	30
Irg1l regulates neuromast size via metabolic reprogramming to promote supporting cell proliferation	30
The cell biologist’s guide to detecting and modulating membrane phospholipids	30
Reticular adhesions are assembled at flat clathrin lattices and opposed by active integrin α5β1	30
Coronin 1C restricts endosomal branched actin to organize ER contact and endosome fission	29
Mitochondrial fission controls astrocyte morphogenesis and organization in the cortex	29
SUMOylation at the inner nuclear membrane facilitates nuclear envelope biogenesis during mitosis	29
ATG9A facilitates the closure of mammalian autophagosomes	29
Centralspindlin proteins Pavarotti and Tumbleweed along with WASH regulate nuclear envelope budding	29
T cells use focal adhesions to pull themselves through confined environments	29
RCC1 depletion drives protein transport defects and rupture in micronuclei	29
The role of midbody-associated mRNAs in regulating abscission	29
Neutrophil serine proteases degrade endothelial cortactin and promote extravasation	28
Ultrastructure of dopaminergic varicosities revealed by cryo-correlative light and electron microscopy	28
Axonal transport of autophagosomes is regulated by dynein activators JIP3/JIP4 and ARF/RAB GTPases	28
The low-density lipoprotein receptor–mTORC1 axis coordinates CD8+ T cell activation	28
LC3B is a cofactor for LMX1B-mediated transcription of autophagy genes in dopaminergic neurons	28
A covalently linked probe to monitor local membrane properties surrounding plasma membrane proteins	28
Autolysosomal exocytosis of lipids protect neurons from ferroptosis	28
A Lifeact-EGFP quail for studying actin dynamics in vivo	28
Hyperstabilization of T cell microvilli contacts by chimeric antigen receptors	28
Mitochondria–ER–PM contacts regulate mitochondrial division and PI(4)P distribution	27
A fluorogenic complementation tool kit for interrogating lipid droplet–organelle interaction	27
OMA1 clears traffic jam in TOM tunnel in mammals	27
A membrane-sensing mechanism links lipid metabolism to protein degradation at the nuclear envelope	27
The bioenergetics of nucleocytoplasmic transport	27
RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursors	27
Plasma membrane-to-lysosome FGR signaling regulates endocytosis-associated lysosome homeostasis	26
How do trypanosome IFT trains choose special tracks?	26
Meiotic nuclear pore complex remodeling provides key insights into nuclear basket organization	26
A proteome-wide yeast degron collection for the dynamic study of protein function	26
Not just protons: Chloride also activates lysosomal acidic hydrolases	26
Synaptotagmin-1 in phase: Condensate biology reveals new insights into the synaptic calcium sensor	26
Centrosome age breaks spindle size symmetry even in cells thought to divide symmetrically	26
Composition and organization of kinetochores show plasticity in apicomplexan chromosome segregation	26
Visualizing ER-phagy and ER architecture in vivo	25
Super-resolution microscopy: Insights into mitochondria–lysosome crosstalk in health and disease	25
Nuclear pore complexes mediate subtelomeric gene silencing by regulating PCNA levels on chromatin	25
A farnesyl-dependent structural role for CENP-E in expansion of the fibrous corona	25
Mechanical control of osteoclast fusion by membrane-cortex attachment and BAR proteins	25
Nodal modulator (NOMO) is a force-bearing transmembrane protein required for muscle differentiation	25
Extracellular vesicles adhere to cells primarily by interactions of integrins and GM1 with laminin	25
PEAK1 Y635 phosphorylation regulates cell migration through association with Tensin3 and integrins	25
Fusion pore dynamics of large secretory vesicles define a distinct mechanism of exocytosis	25
Endothelial depletion of Atg7 triggers astrocyte–microvascular disassociation at blood–brain barrier	24
Lipid packing and local geometry influence septin curvature sensing	24
Polyploidy reprograms epithelial cells for motility and phagocytosis via stress signaling	24
Lactylation stabilizes TFEB to elevate autophagy and lysosomal activity	24
Periodic changes of cyclin D1 mRNA stability are regulated by PC4 modifications in the cell cycle	24
Kinesin-1 autoinhibition facilitates the initiation of dynein cargo transport	24
Light-based modulation of astrocytic calcium for regulation of organelle dynamics and morphogenesis	24
Faa1 membrane binding drives positive feedback in autophagosome biogenesis via fatty acid activation	24
Neuroligin-2 is ubiquitinated by Nedd4l to control developmental astrocyte morphogenesis	23
Mechanometabolism of cell adhesion: Vinculin regulates bioenergetics via RhoA-ROCK	23
Making lipids very unhappy to discover how they bind to proteins	23
Integration of cell wall synthesis and chromosome segregation during cell division in Caulobacter	23
A plant-specific bridging adaptor for amphisome biogenesis	23
α-Catenin force-sensitive binding and sequestration of LZTS2 leads to cytokinesis failure	23
JIP4 and RILPL1 utilize opposing motor force to dynamically regulate lysosomal tubulation	23
Tubulin isotypes contribute opposing properties to balance anaphase spindle morphogenesis	23
Inhibition of endolysosome fusion increases exosome secretion	23
Splicing under stress: A matter of time and place	23
Actin arginylation alters myosin engagement and F-actin patterning despite structural conservation	23
Tension-induced suppression of allosteric conformational changes coordinates kinesin-1 stepping	23
An interaction between β′-COP and the ArfGAP, Glo3, maintains post-Golgi cargo recycling	22
Structural characterization and inhibition of the interaction between ch-TOG and TACC3	22
Clathrin: Bender or bystander?	22
Ist2 is a phospholipid scramblase that links lipid transport at the ER to organelle homeostasis	22

Rickettsia parkeri forms extensive, stable contacts with the rough endoplasmic reticulum	22
NuMA is a mitotic adaptor protein that activates dynein and connects it to microtubule minus ends	22
Cell polarity changes in cancer initiation and progression	22
Prolonged depletion of profilin 1 or F-actin causes an adaptive response in microtubules	21
NME3 binds to phosphatidic acid and mediates PLD6-induced mitochondrial tethering	21
Long live lamins	21
Ca2+ binding to Esyt modulates membrane contact site density in Drosophila photoreceptors	21
Tailored assemblies of COPII proteins in secretion	21
The autophagy protein ATG-9 regulates lysosome function and integrity	21
IRSp53 promotes postsynaptic density formation and actin filament bundling	21
p24 family Tango(1) at the endoplasmic reticulum exit site to organize cargo exit	21
Scrib organizes cortical actomyosin clusters to maintain adherens junctions and angiogenic sprouting	21
Plasticity of mitotic cyclins in promoting the G2–M transition	21
Inwardly rectifying potassium channels promote directional sensing during neutrophil chemotaxis	21
The p97 ATPase and its adaptor UBXD8 maintain peroxisome pools by preventing pexophagy	21
CDR2 is a dynein adaptor recruited by kinectin to regulate ER sheet organization	21
Directed stochasticity: Building biomolecular condensates in the right place	21
An inducible multiciliated cell line resolves proteome dynamics and identifies CDK7 as a conserved regulator	21
Binucleated human hepatocytes arise through late cytokinetic regression during endomitosis M phase	21
Murine glial protrusion transcripts predict localized Drosophila glial mRNAs involved in plasticity	21
Painting lysosomes to study organelle heterogeneity	21
A specialized tyrosine-based endocytosis signal in MR1 controls antigen presentation to MAIT cells	21
Eosinophils promote a second wave of postnatal smooth muscle differentiation in intestinal villi	21
Phosphoproteomic identification of Mos–MAPK targets in meiotic cell cycle and asymmetric oocyte divisions	21
Ubiquitinating the way to T cell metabolism	21
p62 sorts Lupus La and selected microRNAs into breast cancer-derived exosomes	21
Centriole growth is limited by the Cdk/Cyclin-dependent phosphorylation of Ana2/STIL	20
Bridging condensins mediate compaction of mitotic chromosomes	20
RFWD3 promotes ZRANB3 recruitment to regulate the remodeling of stalled replication forks	20
ARHGAP17 regulates the spatiotemporal activity of Cdc42 at invadopodia	20
The emerging roles of non-canonical ubiquitination in proteostasis and beyond	20
Determining how many cells to average for statistical testing of microscopy experiments	20
PI(4,5)P2 diffuses freely in the plasma membrane even within high-density effector protein complexes	20
LYSMD proteins promote activation of Rab32-family GTPases for lysosome-related organelle biogenesis	20
The minus-end depolymerase KIF2A drives flux-like treadmilling of γTuRC-uncapped microtubules	20
PEX14 acts as a molecular link between optineurin and the autophagic machinery to induce pexophagy	20
Pexophagy meets physiology	20
Fission-independent compartmentalization of mitochondria during budding yeast cell division	20
Nuclear poly-glutamine aggregates rupture the nuclear envelope and hinder its repair	20
APOE traffics to astrocyte lipid droplets and modulates triglyceride saturation and droplet size	20
E- and N-cadherin drive hepatic polarity and lumen elongation via opposing effects on RhoA activity	20
The Ndc80-Cdt1-Ska1 complex is a central processive kinetochore–microtubule coupling unit	19
Unveiling the TRAPP: The role of plant TRAPPII in adaptive growth decisions	19
Balancing cell polarity PARts through dephosphorylation	19
Vacuolar pH regulates clathrin-mediated endocytosis through TORC1 signaling during replicative aging	19
ARF3 weights the balance for prostate cancer metastasis	19
ER as master regulator of membrane trafficking and organelle function	19
Tepsin and AP4 mediate transport from the trans-Golgi to the plant-like vacuole in toxoplasma	19
RTN3 and RTN4: Architects of SARS-CoV-2 replication organelles	19
Oiling the wheels of nuclear division: SUMOylation regulates the expansion of the mitotic nuclear membrane	19
FUT8-mediated core fucosylation stabilizes TMEM67 to promote ciliogenesis	19
CLASPs stabilize the pre-catastrophe intermediate state between microtubule growth and shrinkage	19
Structural response of microtubule and actin cytoskeletons to direct intracellular load	19
A collagen IV fluorophore knock-in toolkit reveals trimer diversity in C. elegans basement membranes	19
Deep learning techniques and mathematical modeling allow 3D analysis of mitotic spindle dynamics	19
Nanoscale architect: Illuminating the key organizer of the fruit fly’s sensory world	19
RAB-10 cooperates with EHBP-1 to capture vesicular carriers during post-Golgi exocytic trafficking	19
Claudin 7 suppresses invasion and metastasis through repression of a smooth muscle actin program	19
Vinculin is required for interkinetic nuclear migration (INM) and cell cycle progression	19
High-content phenotyping reveals Golgi dynamics and their role in cell cycle regulation	19
Expanded directly binds conserved regions of Fat to restrain growth via the Hippo pathway	18
Protein Kinase C promotes peroxisome biogenesis and peroxisome–endoplasmic reticulum interaction	18
LGI3/2–ADAM23 interactions cluster Kv1 channels in myelinated axons to regulate refractory period	18
AMPK regulates phagophore-to-autophagosome maturation	18
Molding a PI(3,5)P2 biosensor	18
Centrosome-organized plasma membrane infoldings linked to growth of a cortical actin domain	18
Early proteostasis of caveolins synchronizes trafficking, degradation, and oligomerization to prevent toxic aggregation	18
ISWI chromatin remodeling complexes recruit NSD2 and H3K36me2 in pericentromeric heterochromatin	18
Landscape expansion microscopy reveals interactions between membrane and phase-separated organelles	18
SIR telomere silencing depends on nuclear envelope lipids and modulates sensitivity to a lysolipid	18
Liquid–liquid phase separation mediates the formation of herpesvirus assembly compartments	18
WAVE complex forms linear arrays at negative membrane curvature to instruct lamellipodia formation	18
Zn2+ decoration of microtubules arrests axonal transport and displaces tau, doublecortin, and MAP2C	18
VASH1–SVBP and VASH2–SVBP generate different detyrosination profiles on microtubules	18
One step 4× and 12× 3D-ExM enables robust super-resolution microscopy of nanoscale cellular structures	18
JIP3 interacts with dynein and kinesin-1 to regulate bidirectional organelle transport	18
Kinetochores get a grip!	17
Chromosome segregation synchrony in S. pombe is noise limited and arises without positive feedback	17
Postsynaptic BMP signaling regulates myonuclear properties in Drosophila larval muscles	17
An S-acylated N-terminus and a conserved loop regulate the activity of the ABHD17 deacylase	17
Synaptotagmin-1 undergoes phase separation to regulate its calcium-sensitive oligomerization	17
A pyrophosphatase that regulates lipid precursors of N-glycosylation	17
Correction: Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis	17
A substrate-interacting region of Parkin directs ubiquitination of the mitochondrial GTPase Miro1	17
XAF1 promotes colorectal cancer metastasis via VCP–RNF114–JUP axis	17
ER export via SURF4 uses diverse mechanisms of both client and coat engagement	17
A second chance at yeast early endosomes	17
The septin cytoskeleton: Heteromer composition defines filament function	17
Small lipid droplets are rigid enough to indent a nucleus, dilute the lamina, and cause rupture	17
Anillin mediates unilateral furrowing during cytokinesis by limiting RhoA binding to its effectors	17
A versatile cortical pattern-forming circuit based on Rho, F-actin, Ect2, and RGA-3/4	17
Cargo adaptors use a handhold mechanism to engage with myosin V for organelle transport	17
Ubiquitin chain variability directs substrates of the Tul1 ubiquitin ligase complex to different degradation pathways	17
Regulation of Cajal bodies: Unexpected connection to 60S ribosomes	17
Actomyosin contractility and a threshold of cadherin cell adhesion are required during tissue fusion	17