Journal of Biological Chemistry

Article	Citations
Structural and functional characterization of the IpaD π-helix reveals critical roles in DOC interaction, T3SS apparatus maturation, and Shigella virulence	295
The conformation of tetraspanins CD53 and CD81 differentially affects their nanoscale organization and interaction with their partners	271
Cryo-EM structure of ACE2-SIT1 in complex with tiagabine	134
Identification of the N-terminal residues responsible for the differential microdomain localization of CYP1A1 and CYP1A2	128
Analysis of eIF4E-family members in fungi contributes to their classification in eukaryotes	126
Correction: Characterization of a cytochrome P450 that catalyzes the O-demethylation of lignin-derived benzoates	119
Structural and functional analysis of a bile salt hydrolase from the bison microbiome	115
A type II toxin–antitoxin system is responsible for the cell death at low temperature in Pseudomonas syringae Lz4W lacking RNase R	113
Abstract 1981 Investigating the Pro-Inflammatory and Pro-Oxidant Effects of Wood Smoke in Murine Macrophages	95
Abstract 2332 Effectiveness of antimicrobial peptides on the growth of select ESKAPE pathogens	92
Abstract 2003 Measuring the substrate specificity of esterases for alcohol substituents using terbium luminescence	89
Abstract 2006 Assessing Alterations in Hepatic Oxidation In MASLD/MASH via Preclinical Deuterium Metabolic MRI	87
Abstract 1357 Design of a biotinylated [Cp*Co(III)Cl2]2-Streptavidin Artificial Metalloenzyme for C-H bond activation	87
Abstract 2018 Lon Protease: The Jaws of Life	86
Abstract 2214 Characterization of the metastatic TIME by subcellular spatial profiling	85
Abstract 2016 Embracing Collaborations: Doing what we love and loving what we do	84
Abstract 1559 Empowering Researchers with Accessible Molecular Animation Tools in Blender	82
Abstract 1599 The P2 Old protein provides broad anti-phage defense and is uninhibited by nucleotide	81
Abstract 2049 Telomerase Expression Levels Vary During Meiosis in Tetrahymena Thermophila	81
Abstract 1869 In vivo pulse-chase in C. elegans reveals intestinal histone turnover changes upon starvation	79
Abstract 2477 Design and Synthesis of Naphthoquinone Derivatives as Antibiotics through Inhibition of the Sodium-Dependent NADH:Ubiquinone Oxidoreductase (Na+-NQR) in Pathogenic Bacteria	76
Abstract 1272 Nephroprotective effect of the hydroalcoholic fraction of the medium polarity extract of Potentilla indica in rats with type 2 diabetes	75
Abstract 1585 Identification of translocon-associated protein subunit beta (TRAPβ) as a regulator of cell cycle progression and apoptosis in human colorectal cancer cells	74
Abstract 1005 Mitotic Abnormalities in HPV+ Integrated Cervical and Intestinal Carcinomas by Histopathological Evaluation	73
Abstract 1032 Turning the Oxygen and Vitamin Dials	71

Abstract 1713 Nitric-oxide Independent Signaling Through Bacterial Heme-Nitric Oxide or Oxygen Binding Proteins (H-NOX) in Caulobacter crescentus	69
Abstract 1247 AC01: A Natural Compound with Anti-Cancer Activity Targeting Wnt/ß-catenin Signaling Pathway	67
Abstract 1515 Investigating the Role of Lipid Metabolism in Induced Pluripotent Stem Cells with High-Level Mitochondrial DNA Mutation Heteroplasmy	67
Abstract 2235 Viral SF1B helicases as antiviral targets	67
Abstract 1777 Investigating the Role of Pyruvate Dehydrogenase (PDH) Phosphorylation in Biofilm Formation in Δhnox Caulobacter crescentus	66
Abstract 2062 Oxidant-induced damage to equine erythrocytes from exposure to galloyl derivatives and from exposure to leaf extracts of plant species in the family Sapindaceae (sub-family Hippocastanoi	65
Abstract 2090 The Effect of Cellular Differentiation on Adeno-Associated Viral Vector Genome Status	65
Abstract 1395 Glycine-N-methyltransferase is not necessary for age-dependent Drosophila photoreceptor survival	65
Abstract 1549 Heme reduction in CcmFH, a key enzyme within the bacterial System I cytochrome c biogenesis pathway	65
Abstract 2679 Mentoring for Impact: Empowering Biochemistry Undergraduates and Building Futures	61
Abstract 1874 Exploring the Role of catp-6 at the C. elegans Neuromuscular Junction	61
Abstract 1708 Student Perspectives on AI in Higher Education: Insights from Biochemistry and Molecular Biology Classrooms	61
Abstract 1915 NHE9 Modulates Exosome Communication to Enhance Macrophage-Mediated Cardiomyocyte Repair under Oxidative Stress	59
Abstract 1488 CTCF knockdown rescues the MAPK signaling pathway in Vezf1 null murine embryonic stem cells	59
Abstract 2100 Carboxypeptidase O and glutamate carboxypeptidase II have redundant functions in C-terminal amino acid cleavage	59
Abstract 1743 Nanopore sequencing of intact aminoacylated tRNAs	58
Abstract 2384 Active Site Residues of Coq11, an Atypical Short-Chain Dehydrogenase/Reductase, are Essential for Efficient Coenzyme Q Biosynthesis	57
Abstract 1027 Control of Nucleotide Metabolism and Cell Growth	56
Abstract 1221 The Role of FGFRL1 in Esophageal Carcinoma: Expression Patterns and Clinical Implications	56
Abstract 2749 Mentoring Undergraduate Students at Scientific Meetings: A Framework for Boosting Engagement and Persistence in Research	56
Abstract 1180 Development of Liposome-Based Therapeutics to Modulate Microglial Activation for Neurodegenerative Disease Treatment	56
Abstract 1250 Understanding Heterotrophic Acetate Metabolism in Chlamydomonas reinhardtii	56
Abstract 1705 Characterizing the relationship between histone demethylases ELF6 and REF6 and the chromatin remodeler PKL in H3K27me3 homeostasis	56
A bacterial actin with high ATPase activity regulates the polymerization of a partner MreB isoform essential for Spiroplasma swimming motility	55
Proximal cysteine residues in proteins promote Nε-carboxyalkylation of lysine residues by α-dicarbonyl compounds	55
The human autophagy-initiating complexes ULK1C and PI3KC3-C1	55
Nesprin-2 is a novel scaffold protein for telethonin and FHL-2 in the cardiomyocyte sarcomere	54
Sialyltransferase ST6GAL-1 mediates resistance to chemoradiation in rectal cancer	54
Integrin mediates cell entry of the SARS-CoV-2 virus independent of cellular receptor ACE2	54
Novel Z-DNA binding domains in giant viruses	53
Cannabinoid CB2 receptors are upregulated via bivalent histone modifications and control primary afferent input to the spinal cord in neuropathic pain	53
A short-chain acyl-CoA synthetase that supports branched-chain fatty acid synthesis in Staphylococcus aureus	52
Transmembrane serine protease TMPRSS2 implicated in SARS-CoV-2 infection is autoactivated intracellularly and requires N-glycosylation for regulation	52
Click chemistry and optogenetic approaches to visualize and manipulate phosphatidic acid signaling	52
Long-range allostery mediates the regulation of plasminogen activator inhibitor-1 by cell adhesion factor vitronectin	52
A novel gain-of-function phosphorylation site modulates PTPN22 inhibition of TCR signaling	51
PLTP is a p53 target gene with roles in cancer growth suppression and ferroptosis	51
IL4I1 overexpression protects against nonalcoholic fatty liver disease in part by inhibiting the AKT/FOXO1 pathway-mediated Th17 cell differentiation	51
Peroxynitrite detoxification by Trypanosoma cruzi heme peroxidase supports parasite survival in macrophages	50
Purinosomes spatially co-localize with mitochondrial transporters	49
Maternal obesity alters histone modifications mediated by the interaction between EZH2 and AMPK, impairing neural differentiation in the developing embryonic brain cortex	49
The E3 ubiquitin ligase RNF126 facilitates quality control of unimported mitochondrial membrane proteins	49
Protocatechuate hydroxylase is a novel group A flavoprotein monooxygenase with a unique substrate recognition mechanism	49
Live cell analysis of mobility and decay kinetics of the histone variant H3.3	49
A tribute to Sidney Altman, one of the architects of modern RNA biology	48
A genus-specific nsp12 region impacts polymerase assembly in Alphacoronavirus and Gammacoronavirus	47
Characterization of ribosome stalling and no-go mRNA decay stimulated by the fragile X protein, FMRP	47
Nonfunctional coq10 mutants maintain the ERMES complex and reveal true phenotypes associated with the loss of the coenzyme Q chaperone protein Coq10	47
Targeting HNRNPA2B1 to overcome chemotherapy resistance in gastric cancer stem cells: Mechanisms and therapeutic potential	46
The activity of the ribonucleotide monophosphatase UmpH is controlled by interaction with the GlnK signaling protein in Escherichia coli	46

Single-cell profiling identifies LIN28A mRNA targets in the mouse pluripotent-to-2C-like transition and somatic cell reprogramming	46
Legius syndrome mutations in the Ras-regulator SPRED1 abolish its membrane localization and potentially cause neurodegeneration	46
A biallelic variant of the RNA exosome gene, EXOSC4, associated with neurodevelopmental defects impairs RNA exosome function and translation	46
Crystal structure and mechanistic studies of the PPM1D serine/threonine phosphatase catalytic domain	45
Redox imbalance induces remodeling of glucose metabolism in Rhipicephalus microplus embryonic cell line	45
The green ESCRTs: Newly defined roles for ESCRT proteins in plants	45
A conserved phosphorylation mechanism for regulating the interaction between the CMG replicative helicase and its forked DNA substrate	44
Enriched G4 forming repeats in the human genome are associated with robust well-coordinated transcription and reduced cancer transcriptome variation	44
Reconstitution of purified membrane protein dimers in lipid nanodiscs with defined stoichiometry and orientation using a split GFP tether	44
Catalytically distinct metabolic enzyme isocitrate dehydrogenase 1 mutants tune phenotype severity in tumor models	44
Methionine cycle inhibition disrupts antioxidant metabolism and reduces glioblastoma cell survival	44
Declining activity of serum response factor in aging aorta in relation to aneurysm progression	44
Artesunate enhances the efficacy of enzalutamide in advanced prostate cancer	44
The late-stage steps of Burkholderia cenocepacia protein O-linked glycan biosynthesis are conditionally essential	43
Hhatl ameliorates endoplasmic reticulum stress through autophagy by associating with LC3	43
Rare variants of DNA ligase 1 show distinct mechanisms of deficiency	43
DNA polymerase ζ has robust reverse transcriptase activity relative to other cellular DNA polymerases	43
The LDL receptor-related protein 1 (LRP1) facilitates ACE2-mediated endocytosis of SARS-CoV2 spike protein-containing pseudovirions	43
The molecular principles underlying diverse functions of the SLC26 family of proteins	43
Combined inhibition of aurora kinases and Bcl-xL induces apoptosis through select BH3-only proteins	42
Cell targeting by the bicomponent leukocidin subunit HlgB drives Staphylococcus aureus pathophysiology	42
Negative cooperativity underlies dynamic assembly of the Par complex regulators Cdc42 and Par-3	42
Metabolic control of luteinizing hormone-responsive ovarian steroidogenesis	42
Expression of hypoxia inducible factor–dependent neuropeptide Y receptors Y1 and Y5 sensitizes hypoxic cells to NPY stimulation	41
Activity-dependent modulation of neuronal KV channels by retinoic acid enhances CaV channel activity	41
Abstract 1292: Reactive Oxygen Species Production and Regulation in Human Cell	41
SARS-CoV-2 beta variant substitutions alter spike glycoprotein receptor binding domain structure and stability	40
Abstract 1892: Characterization of a 7-deazaguanine-based bacterial modification system	40
Abstract 1531: Facilitating the collaborative scientific process through an interdisciplinary undergraduate protein modeling course	40
The permanently chaperone-active small heat shock protein Hsp17 from Caenorhabditis elegans exhibits topological separation of its N-terminal regions	40
Abstract 2625: Human brain sialoglycan ligand for CD33, a microglial inhibitory Siglec implicated in Alzheimer's disease	40
The development of a high-affinity conformation-sensitive antibody mimetic using a biocompatible copolymer carrier (iBody)	40
Dimers of D76N-β2-microglobulin display potent antiamyloid aggregation activity	40
Mutational and biophysical analyses reveal a TFIIIC binding region in the TFIIF-related Rpc53 subunit of RNA polymerase III	40
The two paralogous copies of the YoeB–YefM toxin–antitoxin module in Staphylococcus aureus differ in DNA binding and recognition patterns	39
Protein arginine methyltransferase 5 is essential for oncogene product EWSR1-ATF1-mediated gene transcription in clear cell sarcoma	39
Division of labor between the pore-1 loops of the D1 and D2 AAA+ rings coordinates substrate selectivity of the ClpAP protease	39
Characterization of a lytic polysaccharide monooxygenase from Aspergillus fumigatus shows functional variation among family AA11 fungal LPMOs	38
Abstract 2318: Does Order Matter when Teaching Noncovalent Interactions: A Comparison of the Sequence of Explicit Instruction and Problem Solving	38
A transthyretin monomer intermediate undergoes local unfolding and transient interaction with oligomers in a kinetically concerted aggregation pathway	38
Binding with heat shock cognate protein HSC70 fine-tunes the Golgi association of the small GTPase ARL5B	38
A tumor microenvironment-activated metal-organic framework–based nanoplatform for amplified oxidative stress–induced enhanced chemotherapy	38
A higher plant FAD synthetase is fused to an inactivated FAD pyrophosphatase	38
Anionic lipid vesicles have differential effects on the aggregation of early onset-associated α-synuclein missense mutants	38
Hepatocyte polarity establishment and apical lumen formation are organized by Par3, Cdc42, and aPKC in conjunction with Lgl	38
Abstract 2236: Creation of Virtual Affinity Groups to Provide Support to Women Faculty in STEM Across a Consortium of Public Liberal Arts Colleges	38
N-glycosylation is a potent regulator of prion protein neurotoxicity	37
Abstract 1487: Role of calcium in mediating membrane tension and synaptic plasticity	37
Loss of full-length DNA replication regulator Rif1 in two-cell embryos is associated with zygotic transcriptional activation	37
Abstract 2699: Unique interactions and functions of the mitochondrial small Tims in Trypanosoma brucei	37
Two types of peptides derived from the neurotoxin GsMTx4 inhibit a mechanosensitive potassium channel by modifying the mechanogate	37
Divergent allostery reveals critical differences between structurally homologous regulatory domains of Plasmodium falciparum and human protein kinase G	37
Structural and functional studies of legumain–mycocypin complexes revealed a competitive, exosite-regulated mode of interaction	37
Abstract 1927: Cloning and recombinant expression of a lactobacillus ferulic acid esterase for potential use in beer production	37
FK506-binding protein-like and FK506-binding protein 8 regulate dual leucine zipper kinase degradation and neuronal responses to axon injury	37
Cover	36
Abstract 2544: Radical SAM aminomutases catalyzing beta-amino acid biosynthesis for salt tolerance in methanogenic archaea	36
Abstract 1272 Structural basis for double-strand-break repair by a group II intron-like RT	36
Staphylococcal Periscope proteins Aap, SasG, and Pls project noncanonical legume-like lectin adhesin domains from the bacterial surface	36
Abstract 2039 MDH CURES Community: A Supportive Network for Faculty to Increase Student Retention and Learning	36
Abstract 2284: Elucidating FIBCD1 Binding Partners	36
Abstract 2005 Interplay between charge distribution and DNA in shaping HP1 paralog phase separation and localization	35
G protein–coupled estrogen receptor 1 ameliorates nonalcoholic steatohepatitis through targeting AMPK-dependent signaling	35
Abstract 1497: The structural variance of amyloid peptides influences oxidative activity in the human brain	35
Abstract 2018 The Anti-Cancer Effect of Acmella Extracts in Ovarian Cancer	35
The histamine H3 receptor modulates dopamine D2 receptor–dependent signaling pathways and mouse behaviors	35
Abstract 2091: Living in the cold without brown adipose tissue lipolysis	35
Abstract 1500 Understanding the role of galactose and glucose on the composition of E. coli extracellular polymeric substance and biofilm growth	35
Abstract 2090: Probing Non-Canonical A•C Base Pairs in DNA using SERS	35
Abstract 2227 Mammalian Argonaute represses pericentromeric lncRNAs to maintain genome stability	34
Abstract 1401: Diptoindonesin G is a middle domain HSP90 modulator for cancer treatment	34
Abstract 1126 Generative Artificial Intelligence in Molecular Design and Virtual Screening of Novel Caspase-1 Inhibitors	34
Phosphorylation of the novel mTOR substrate Unkempt regulates cellular morphogenesis	34
H2O2 transit through the mitochondrial intermembrane space promotes tumor cell growth in vitro and in vivo	33
Abstract 2015: Evaluating effect of metalloproteinases and their natural inhibitors on blood brain barrier	33
Abstract 2274 Roles of phosphatidylinositol 3,4-bisphosphate in phagocytosis and bacterial invasion.	33
Cover	33
Abstract 1518: BNIP3 protein abundance is controlled by phosphorylation	33
Abstract 2309: Using Support Vector Machine Classification to Predict NKX2-5 DNA Binding Sites	33
Abstract 1294 Strategies for improving diversity, inclusion and belonging within undergraduate research laboratories	33

Multiple Mycobacterium abscessus O-acetyltransferases influence glycopeptidolipid structure and colony morphotype	33
Abstract 2386: DNP-NMR as a tool for probing the regulation of PKC signaling by membrane dissolved phorbol esters	33
Cover	33
Abstract 1631 The Ability of Metabolic Enzymes to Utilize Nicotinamide Adenine Dinucleotide Covalently Attached to RNA 5'-ends	32
Abstract 1217 SARS-CoV-2 Main Protease Inhibitor High-Throughput Screen	32
Abstract 1611 Coactivator condensation drives cell lineage specification	32
A phase transition reduces the threshold for nicotinamide mononucleotide-based activation of SARM1, an NAD(P) hydrolase, to physiologically relevant levels	32
Abstract 1187 A novel activity of the RAD52 protein that is essential for the viability of BRCA-deficient breast and ovarian cancer cells	32
Abstract 1255 Deciphering complexity of GPCR signaling in health and disease	32
Abstract 1265 Mutants on Mars: Directed Evolution of Halophile Enzyme Activity	32
Structural basis of membrane machines that traffick and attach heme to cytochromes	32
Abstract 1594 Immune-enhancing Effects of Lipid Extracted from Arctoscopus japonicus Eggs on Immune-suppressed Mice	31
Abstract 2374 Structural Insights into the Activation Mechanism of Human ClpXP	31
Abstract 2204 Subcellular Expression of Heat-Shock Protein in the Coral Holobiont	31
N-glycan antennal modifications are altered in Caenorhabditis elegans lacking the HEX-4 N-acetylgalactosamine-specific hexosaminidase	31
Differentiation-linked changes in the biosynthesis and turnover of sphingomyelins in rat male germ cells: Genes involved and effects of testosterone	31
Abstract 1141 S100A12 thermodynamic stability and misfolding properties: Assessing the capacity of S100A12 to misfold into amyloid-like structures	31
Surface electrostatics dictate RNA-binding protein CAPRIN1 condensate concentration and hydrodynamic properties	31
Abstract 2389 Biophysical Characterization of Novel Modulators of PRL3	31
Abstract 1853 Transcriptional regulation of the RAB8A GTPase by CK2 kinase in leukemia	31
Abstract 1591 Enhancing biochemical yield in S. cerevisiae	31
Abstract 2349 Modulation of ENPP1 Activity and 2'3'-cGAMP Degradation in Ovarian Cancer Cell Lines via Loadable Pre-formed Lipid Nanoparticles	31
Correction: AMP-activated protein kinase α1 promotes atherogenesis by increasing monocyte-to-macrophage differentiation	31
Abstract 1039 Quantifying the levels of Queuosine metabolites in the human diet	31
Abstract 1688 Expression, Purification, and Characterization Attempts of Glucan Phosphatase LSF1	30
Ion channel chameleons: Switching ion selectivity by alternative splicing	30
Abstract 1366: Compounds enhancing poly(3-hydroxybutyrate) storage: cell membrane interfering agent 2-phenylethanol combined with nitrogen starvation triggered poly(3-hydroxybutyrate) accumulation in	30
Identification of nonhistone substrates of the lysine methyltransferase PRDM9	30
Abstract 2370 RAD52-BRCA synthetic lethality: a search for the critical RAD52 activity	30
Abstract 1187: A Quantitative Comparison of the Knockdown Efficiencies of CRISPR/Cas9 and CRISPR-Cas12 in Caenorhabditis elegans	30
Abstract 2022: Regulation of Estrogen Receptor Signaling by FKBP52 in Breast Cancer Cells	30
Abstract 2716: The Prevalence of Rs5219 on the KCNJ11 Gene and Its Correlation to Type 2 Diabetes in the Hispanic/Latino Population in California	30
Abstract 2060 Exploring the interplay between amino acids, lysosomes, and iron homeostasis	30
Pre-rRNA facilitates the recruitment of RAD51AP1 to DNA double-strand breaks	30
Abstract 1430 MALDI Spatial Imaging to Characterize the Competition for Metabolic Resources During Parasitoid Wasp Infection of Fly Larvae	30
Abstract 2653: Arachidin-1 Enhances the Anticancer Effects of Paclitaxel in Triple-Negative Breast Cancer Cells	30
Abstract 1369 Harnessing plant specialized metabolism for new medicines through synthetic biology	29
Abstract 1473: Modeling Binding of Beta-site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Aminoquinoline (68 K) for Possible Treatment of Alzheimer's Disease	29
C9orf72-associated dipeptide protein repeats form A11-positive oligomers in amyotrophic lateral sclerosis and frontotemporal dementia	29
Abstract 1517 Examining the effect of L-rhamnose metabolism on the transcriptome of Escherichia coli	29
Functionally redundant formate dehydrogenases enable formate-dependent growth in Methanococcus maripaludis	29
Lipid biosynthesis perturbation impairs endoplasmic reticulum–associated degradation	29
Comparative analysis of the physical properties of murine and human S100A7: Insight into why zinc piracy is mediated by human but not murine S100A7	29
Abstract 2006 Determining the Effects of Motif A Phosphorylation on SIRT1 Activity	29
Abstract 1895 Educational Equity in a Community College Classroom - Using UR as a High Impact Practice Tool	29
Abstract 1812: The Interplay of Acetylation and Ubiquitination	29
Exploration of O-GlcNAc transferase glycosylation sites reveals a target sequence compositional bias	29
Abstract 1007 Novel Interactions of Potato Spindle Tuber Viroid RNA with Pokeweed Antiviral Protein	29
Abstract 1370: How Selection Bias and Data Interpretation Contribute to Disparities in Health Outcomes and Artificial Intelligence Development	28
Transportin 1 is a major nuclear import receptor of the nitric oxide synthase interacting protein	28
Phosphorylation alters the mechanical stiffness of a model fragment of the dystrophin homologue utrophin	28
Abstract 2374: MAP Kinase Phosphatases as Nodal Signal Regulators in Health and Disease	28
Abstract 1365: Interplay Between Nicotine, BDNF, and a β-Adrenergic Receptor Blocker in Regulating Cisplatin Resistance in Lung Cancer Cells	28
Abstract 1947 Exploring the Interplay of Social- Economic, and Racial Disparities Stress and Their Impact on Breast Cancer, with a Focus on Triple Negative Breast Cancer and Hormonal Imbalance-Induced	28
Abstract 1165: Potential “Release-on-Demand” Metallopolymer Coatings For Drug-Release, Biofabrication, and In Vitro Experimental Control	28
Natural and synthetic 2-oxoglutarate derivatives are substrates for oncogenic variants of human isocitrate dehydrogenase 1 and 2	28
The Stathmin-2 membrane-targeting domain is required for axon protection and regulated degradation by DLK signaling	28
Abstract 1708 CTBP1 Mutation Affects Neuronal Stem Cell Migration	28
Abstract 1259 Biochemical Investigation and Evolutionary Comparison of the Mechanism of the Initiation of DNA Replication in Eukaryotic Cells	28
Abstract 2178: Understanding TAOK1 dysfunction in neurodevelopmental disorders using human stem cell derived models	28
Molecular basis of IFN-γ-induced STAT3 phosphorylation stimulated by Sendai virus C protein	28
Antimicrobial peptides selectively target malaria parasites by a cholesterol-dependent mechanism	27
Quantification of NADH:ubiquinone oxidoreductase (complex I) content in biological samples	27
Krüppel-like factor 12 regulates aging ovarian granulosa cell apoptosis by repressing SPHK1 transcription and sphingosine-1-phosphate (S1P) production	27
Glycogen synthase kinase homolog Rim11 regulates lipid synthesis through the phosphorylation of Pah1 phosphatidate phosphatase in yeast	27
Cryo-EM structures reveal the PP2A–B55α and Eya3 interaction that can be disrupted by a peptide inhibitor	27
Endoplasmic reticulum protein BIK binds to and inhibits mitochondria-localized antiapoptotic proteins	27
HRI protein kinase in cytoplasmic heme sensing and mitochondrial stress response: Relevance to hematological and mitochondrial diseases	27
An immunogenic cell injury module for the single-cell multiplexed activity metabolomics platform to identify promising anti-cancer natural products	27
Critical roles of protein disulfide isomerases in balancing proteostasis in the nervous system	27
p53 regulates skeletal muscle mitophagy and mitochondrial quality control following denervation-induced muscle disuse	27
Argonaute 1 contributes to the transcriptional silencing of HIV-1	27
Histone acetyltransferase KAT2A modulates neural stem cell differentiation and proliferation by inducing degradation of the transcription factor PAX6	27
Human UFSP1 translated from an upstream near-cognate initiation codon functions as an active UFM1-specific protease	27
DNA polymerase η promotes nonhomologous end joining upon etoposide exposure dependent on the scaffolding protein Kap1	27
CLIC5A binds to and stabilizes the open and active conformation of ezrin	27
Exosome-mediated mRNA delivery in vivo is safe and can be used to induce SARS-CoV-2 immunity	27
Cardiolipin metabolism regulates expression of muscle transcription factor MyoD1 and muscle development	27
mRNA display reveals a class of high-affinity bromodomain-binding motifs that are not found in the human proteome	27
Isoforms of GPR35 have distinct extracellular N-termini that allosterically modify receptor-transducer coupling and mediate intracellular pathway bias	27
Retinal-phospholipid Schiff-base conjugates and their interaction with ABCA4, the ABC transporter associated with Stargardt disease	27
A recombinant technique for mapping functional sites of heterotrimeric collagen helices: Collagen IV CB3 fragment as a prototype for integrin binding	27
Glial fibrillary acidic protein is pathologically modified in Alexander disease	27
Smooth muscle Cxcl12 contributions to vascular remodeling in flow and hypoxia-induced pulmonary hypertension	26
Structural basis for Rab23 activation and a loss-of-function mutation in Carpenter syndrome	26
Copper acquisition in Bacillus subtilis involves Cu(II) exchange between YcnI and YcnJ	26
The role of human Shu complex in ATP-dependent regulation of RAD51 filaments during homologous recombination–associated DNA damage response	26
Conditional lethality and suppressor analysis of plasmid-based temperature-sensitive fabZ expression in Pseudomonas aeruginosa	26
Nrf2-and p53-inducible REDD2/DDiT4L/Rtp801L confers pancreatic β-cell dysfunction, leading to glucose intolerance in high-fat diet-fed mice	26
Translation-independent association of mRNAs that encode protomers of the 5-HT2A-mGlu2 receptor complex	26
Myeloid loss of scaffolding protein menin promotes liver fibrosis via H3K36me3 reprogramming	26
Asialoglycoprotein receptor 1 is a novel PCSK9-independent ligand of liver LDLR cleaved by furin	26
Pancreatic expression of CPT1A is essential for whole body glucose homeostasis by supporting glucose-stimulated insulin secretion	26
Bioluminescence-based assays for quantifying endogenous protein interactions in live cells	26
Nucleotide sugar dehydratases: Structure, mechanism, substrate specificity, and application potential	26