Journal of Biological Chemistry

Papers
(The median citation count of Journal of Biological Chemistry is 0. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
Abstract 1981 Investigating the Pro-Inflammatory and Pro-Oxidant Effects of Wood Smoke in Murine Macrophages316
Abstract 2332 Effectiveness of antimicrobial peptides on the growth of select ESKAPE pathogens277
Abstract 2003 Measuring the substrate specificity of esterases for alcohol substituents using terbium luminescence129
Abstract 1357 Design of a biotinylated [Cp*Co(III)Cl2]2-Streptavidin Artificial Metalloenzyme for C-H bond activation127
Abstract 2006 Assessing Alterations in Hepatic Oxidation In MASLD/MASH via Preclinical Deuterium Metabolic MRI122
Abstract 2018 Lon Protease: The Jaws of Life119
Abstract 2214 Characterization of the metastatic TIME by subcellular spatial profiling117
Abstract 2016 Embracing Collaborations: Doing what we love and loving what we do105
Correction: Characterization of a cytochrome P450 that catalyzes the O-demethylation of lignin-derived benzoates98
Abstract 1395 Glycine-N-methyltransferase is not necessary for age-dependent Drosophila photoreceptor survival94
Abstract 2679 Mentoring for Impact: Empowering Biochemistry Undergraduates and Building Futures90
Abstract 2062 Oxidant-induced damage to equine erythrocytes from exposure to galloyl derivatives and from exposure to leaf extracts of plant species in the family Sapindaceae (sub-family Hippocastanoi90
Abstract 1708 Student Perspectives on AI in Higher Education: Insights from Biochemistry and Molecular Biology Classrooms88
Abstract 1559 Empowering Researchers with Accessible Molecular Animation Tools in Blender87
Abstract 2049 Telomerase Expression Levels Vary During Meiosis in Tetrahymena Thermophila86
Abstract 1599 The P2 Old protein provides broad anti-phage defense and is uninhibited by nucleotide84
Abstract 1869 In vivo pulse-chase in C. elegans reveals intestinal histone turnover changes upon starvation83
Abstract 2477 Design and Synthesis of Naphthoquinone Derivatives as Antibiotics through Inhibition of the Sodium-Dependent NADH:Ubiquinone Oxidoreductase (Na+-NQR) in Pathogenic Bacteria82
Abstract 1585 Identification of translocon-associated protein subunit beta (TRAPβ) as a regulator of cell cycle progression and apoptosis in human colorectal cancer cells80
Abstract 1272 Nephroprotective effect of the hydroalcoholic fraction of the medium polarity extract of Potentilla indica in rats with type 2 diabetes80
Abstract 1005 Mitotic Abnormalities in HPV+ Integrated Cervical and Intestinal Carcinomas by Histopathological Evaluation77
Abstract 1713 Nitric-oxide Independent Signaling Through Bacterial Heme-Nitric Oxide or Oxygen Binding Proteins (H-NOX) in Caulobacter crescentus76
Abstract 1032 Turning the Oxygen and Vitamin Dials76
Abstract 2235 Viral SF1B helicases as antiviral targets75
Abstract 1515 Investigating the Role of Lipid Metabolism in Induced Pluripotent Stem Cells with High-Level Mitochondrial DNA Mutation Heteroplasmy72
Abstract 1247 AC01: A Natural Compound with Anti-Cancer Activity Targeting Wnt/ß-catenin Signaling Pathway71
Abstract 1777 Investigating the Role of Pyruvate Dehydrogenase (PDH) Phosphorylation in Biofilm Formation in Δhnox Caulobacter crescentus70
Abstract 2090 The Effect of Cellular Differentiation on Adeno-Associated Viral Vector Genome Status68
A type II toxin–antitoxin system is responsible for the cell death at low temperature in Pseudomonas syringae Lz4W lacking RNase R67
Abstract 1874 Exploring the Role of catp-6 at the C. elegans Neuromuscular Junction67
Abstract 1549 Heme reduction in CcmFH, a key enzyme within the bacterial System I cytochrome c biogenesis pathway67
Abstract 2100 Carboxypeptidase O and glutamate carboxypeptidase II have redundant functions in C-terminal amino acid cleavage66
Abstract 1488 CTCF knockdown rescues the MAPK signaling pathway in Vezf1 null murine embryonic stem cells65
Abstract 2384 Active Site Residues of Coq11, an Atypical Short-Chain Dehydrogenase/Reductase, are Essential for Efficient Coenzyme Q Biosynthesis61
Abstract 1743 Nanopore sequencing of intact aminoacylated tRNAs61
Abstract 1221 The Role of FGFRL1 in Esophageal Carcinoma: Expression Patterns and Clinical Implications61
Abstract 1915 NHE9 Modulates Exosome Communication to Enhance Macrophage-Mediated Cardiomyocyte Repair under Oxidative Stress61
Abstract 1180 Development of Liposome-Based Therapeutics to Modulate Microglial Activation for Neurodegenerative Disease Treatment60
Abstract 1705 Characterizing the relationship between histone demethylases ELF6 and REF6 and the chromatin remodeler PKL in H3K27me3 homeostasis60
Abstract 1250 Understanding Heterotrophic Acetate Metabolism in Chlamydomonas reinhardtii59
Abstract 1027 Control of Nucleotide Metabolism and Cell Growth59
Abstract 2749 Mentoring Undergraduate Students at Scientific Meetings: A Framework for Boosting Engagement and Persistence in Research59
Structural and functional characterization of the IpaD π-helix reveals critical roles in DOC interaction, T3SS apparatus maturation, and Shigella virulence58
The conformation of tetraspanins CD53 and CD81 differentially affects their nanoscale organization and interaction with their partners58
Analysis of eIF4E-family members in fungi contributes to their classification in eukaryotes58
Identification of the N-terminal residues responsible for the differential microdomain localization of CYP1A1 and CYP1A257
Cryo-EM structure of ACE2-SIT1 in complex with tiagabine57
A novel gain-of-function phosphorylation site modulates PTPN22 inhibition of TCR signaling56
IL4I1 overexpression protects against nonalcoholic fatty liver disease in part by inhibiting the AKT/FOXO1 pathway-mediated Th17 cell differentiation56
Long-range allostery mediates the regulation of plasminogen activator inhibitor-1 by cell adhesion factor vitronectin56
An immunogenic cell injury module for the single-cell multiplexed activity metabolomics platform to identify promising anti-cancer natural products55
Molecular basis of IFN-γ–induced STAT3 phosphorylation stimulated by Sendai virus C protein55
Protocatechuate hydroxylase is a novel group A flavoprotein monooxygenase with a unique substrate recognition mechanism55
Proximal cysteine residues in proteins promote Nε-carboxyalkylation of lysine residues by α-dicarbonyl compounds55
Peroxynitrite detoxification by Trypanosoma cruzi heme peroxidase supports parasite survival in macrophages55
Metabolic control of luteinizing hormone-responsive ovarian steroidogenesis54
PLTP is a p53 target gene with roles in cancer growth suppression and ferroptosis53
Targeted protein posttranslational modifications by chemically induced proximity for cancer therapy53
Legius syndrome mutations in the Ras-regulator SPRED1 abolish its membrane localization and potentially cause neurodegeneration53
Exploration of O-GlcNAc transferase glycosylation sites reveals a target sequence compositional bias53
Isoforms of GPR35 have distinct extracellular N-termini that allosterically modify receptor-transducer coupling and mediate intracellular pathway bias52
Transmembrane serine protease TMPRSS2 implicated in SARS-CoV-2 infection is autoactivated intracellularly and requires N-glycosylation for regulation51
A higher plant FAD synthetase is fused to an inactivated FAD pyrophosphatase51
Negative cooperativity underlies dynamic assembly of the Par complex regulators Cdc42 and Par-351
Cardiolipin metabolism regulates expression of muscle transcription factor MyoD1 and muscle development50
Click chemistry and optogenetic approaches to visualize and manipulate phosphatidic acid signaling50
The late-stage steps of Burkholderia cenocepacia protein O-linked glycan biosynthesis are conditionally essential49
Krüppel-like factor 12 regulates aging ovarian granulosa cell apoptosis by repressing SPHK1 transcription and sphingosine-1-phosphate (S1P) production49
Live cell analysis of mobility and decay kinetics of the histone variant H3.349
A transthyretin monomer intermediate undergoes local unfolding and transient interaction with oligomers in a kinetically concerted aggregation pathway49
Sialyltransferase ST6GAL-1 mediates resistance to chemoradiation in rectal cancer49
Rare variants of DNA ligase 1 show distinct mechanisms of deficiency49
Glycogen synthase kinase homolog Rim11 regulates lipid synthesis through the phosphorylation of Pah1 phosphatidate phosphatase in yeast48
DNA polymerase ζ has robust reverse transcriptase activity relative to other cellular DNA polymerases47
Abstract 1892: Characterization of a 7-deazaguanine-based bacterial modification system46
Retinal-phospholipid Schiff-base conjugates and their interaction with ABCA4, the ABC transporter associated with Stargardt disease46
Abstract 2625: Human brain sialoglycan ligand for CD33, a microglial inhibitory Siglec implicated in Alzheimer's disease46
The molecular principles underlying diverse functions of the SLC26 family of proteins46
Dimers of D76N-β2-microglobulin display potent antiamyloid aggregation activity46
DNA polymerase η promotes nonhomologous end joining upon etoposide exposure dependent on the scaffolding protein Kap146
Activity-dependent modulation of neuronal KV channels by retinoic acid enhances CaV channel activity45
Expression of hypoxia inducible factor–dependent neuropeptide Y receptors Y1 and Y5 sensitizes hypoxic cells to NPY stimulation45
Abstract 1292: Reactive Oxygen Species Production and Regulation in Human Cell45
Abstract 1531: Facilitating the collaborative scientific process through an interdisciplinary undergraduate protein modeling course44
Anionic lipid vesicles have differential effects on the aggregation of early onset-associated α-synuclein missense mutants44
Division of labor between the pore-1 loops of the D1 and D2 AAA+ rings coordinates substrate selectivity of the ClpAP protease44
Abstract 2318: Does Order Matter when Teaching Noncovalent Interactions: A Comparison of the Sequence of Explicit Instruction and Problem Solving44
Protein arginine methyltransferase 5 is essential for oncogene product EWSR1-ATF1-mediated gene transcription in clear cell sarcoma44
SARS-CoV-2 beta variant substitutions alter spike glycoprotein receptor binding domain structure and stability44
Loss of full-length DNA replication regulator Rif1 in two-cell embryos is associated with zygotic transcriptional activation43
Two types of peptides derived from the neurotoxin GsMTx4 inhibit a mechanosensitive potassium channel by modifying the mechanogate43
Abstract 2236: Creation of Virtual Affinity Groups to Provide Support to Women Faculty in STEM Across a Consortium of Public Liberal Arts Colleges43
FK506-binding protein-like and FK506-binding protein 8 regulate dual leucine zipper kinase degradation and neuronal responses to axon injury43
N-glycosylation is a potent regulator of prion protein neurotoxicity42
Abstract 1487: Role of calcium in mediating membrane tension and synaptic plasticity42
Abstract 2699: Unique interactions and functions of the mitochondrial small Tims in Trypanosoma brucei42
Abstract 1927: Cloning and recombinant expression of a lactobacillus ferulic acid esterase for potential use in beer production42
Structural and functional studies of legumain–mycocypin complexes revealed a competitive, exosite-regulated mode of interaction41
Abstract 1272 Structural basis for double-strand-break repair by a group II intron-like RT41
Abstract 2039 MDH CURES Community: A Supportive Network for Faculty to Increase Student Retention and Learning41
Staphylococcal Periscope proteins Aap, SasG, and Pls project noncanonical legume-like lectin adhesin domains from the bacterial surface41
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Abstract 2284: Elucidating FIBCD1 Binding Partners41
Abstract 1497: The structural variance of amyloid peptides influences oxidative activity in the human brain40
The histamine H3 receptor modulates dopamine D2 receptor–dependent signaling pathways and mouse behaviors40
Abstract 2091: Living in the cold without brown adipose tissue lipolysis40
Abstract 2090: Probing Non-Canonical A•C Base Pairs in DNA using SERS40
Abstract 2544: Radical SAM aminomutases catalyzing beta-amino acid biosynthesis for salt tolerance in methanogenic archaea40
Abstract 2005 Interplay between charge distribution and DNA in shaping HP1 paralog phase separation and localization39
G protein–coupled estrogen receptor 1 ameliorates nonalcoholic steatohepatitis through targeting AMPK-dependent signaling39
Abstract 1126 Generative Artificial Intelligence in Molecular Design and Virtual Screening of Novel Caspase-1 Inhibitors39
Abstract 2018 The Anti-Cancer Effect of Acmella Extracts in Ovarian Cancer39
Abstract 2227 Mammalian Argonaute represses pericentromeric lncRNAs to maintain genome stability39
Abstract 1500 Understanding the role of galactose and glucose on the composition of E. coli extracellular polymeric substance and biofilm growth39
Abstract 1518: BNIP3 protein abundance is controlled by phosphorylation38
Phosphorylation of the novel mTOR substrate Unkempt regulates cellular morphogenesis38
H2O2 transit through the mitochondrial intermembrane space promotes tumor cell growth in vitro and in vivo38
Abstract 2015: Evaluating effect of metalloproteinases and their natural inhibitors on blood brain barrier38
Abstract 2386: DNP-NMR as a tool for probing the regulation of PKC signaling by membrane dissolved phorbol esters38
Multiple Mycobacterium abscessus O-acetyltransferases influence glycopeptidolipid structure and colony morphotype38
Abstract 1401: Diptoindonesin G is a middle domain HSP90 modulator for cancer treatment38
Abstract 2309: Using Support Vector Machine Classification to Predict NKX2-5 DNA Binding Sites38
Abstract 2274 Roles of phosphatidylinositol 3,4-bisphosphate in phagocytosis and bacterial invasion.37
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Abstract 1294 Strategies for improving diversity, inclusion and belonging within undergraduate research laboratories37
Abstract 1631 The Ability of Metabolic Enzymes to Utilize Nicotinamide Adenine Dinucleotide Covalently Attached to RNA 5'-ends37
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Abstract 1611 Coactivator condensation drives cell lineage specification36
Abstract 1187 A novel activity of the RAD52 protein that is essential for the viability of BRCA-deficient breast and ovarian cancer cells36
A phase transition reduces the threshold for nicotinamide mononucleotide-based activation of SARM1, an NAD(P) hydrolase, to physiologically relevant levels36
Abstract 1217 SARS-CoV-2 Main Protease Inhibitor High-Throughput Screen36
Abstract 1255 Deciphering complexity of GPCR signaling in health and disease36
Abstract 1265 Mutants on Mars: Directed Evolution of Halophile Enzyme Activity36
Differentiation-linked changes in the biosynthesis and turnover of sphingomyelins in rat male germ cells: Genes involved and effects of testosterone35
Abstract 1141 S100A12 thermodynamic stability and misfolding properties: Assessing the capacity of S100A12 to misfold into amyloid-like structures35
Abstract 2204 Subcellular Expression of Heat-Shock Protein in the Coral Holobiont35
Abstract 2374 Structural Insights into the Activation Mechanism of Human ClpXP35
Abstract 1594 Immune-enhancing Effects of Lipid Extracted from Arctoscopus japonicus Eggs on Immune-suppressed Mice35
Abstract 2349 Modulation of ENPP1 Activity and 2'3'-cGAMP Degradation in Ovarian Cancer Cell Lines via Loadable Pre-formed Lipid Nanoparticles35
Abstract 1591 Enhancing biochemical yield in S. cerevisiae35
Abstract 2389 Biophysical Characterization of Novel Modulators of PRL335
Abstract 1039 Quantifying the levels of Queuosine metabolites in the human diet34
Abstract 2370 RAD52-BRCA synthetic lethality: a search for the critical RAD52 activity34
Correction: AMP-activated protein kinase α1 promotes atherogenesis by increasing monocyte-to-macrophage differentiation34
Abstract 2060 Exploring the interplay between amino acids, lysosomes, and iron homeostasis34
Ion channel chameleons: Switching ion selectivity by alternative splicing34
Abstract 1853 Transcriptional regulation of the RAB8A GTPase by CK2 kinase in leukemia34
Abstract 1688 Expression, Purification, and Characterization Attempts of Glucan Phosphatase LSF134
Abstract 1187: A Quantitative Comparison of the Knockdown Efficiencies of CRISPR/Cas9 and CRISPR-Cas12 in Caenorhabditis elegans34
Abstract 1430 MALDI Spatial Imaging to Characterize the Competition for Metabolic Resources During Parasitoid Wasp Infection of Fly Larvae34
Abstract 2716: The Prevalence of Rs5219 on the KCNJ11 Gene and Its Correlation to Type 2 Diabetes in the Hispanic/Latino Population in California33
Abstract 2653: Arachidin-1 Enhances the Anticancer Effects of Paclitaxel in Triple-Negative Breast Cancer Cells33
Comparative analysis of the physical properties of murine and human S100A7: Insight into why zinc piracy is mediated by human but not murine S100A733
Abstract 1366: Compounds enhancing poly(3-hydroxybutyrate) storage: cell membrane interfering agent 2-phenylethanol combined with nitrogen starvation triggered poly(3-hydroxybutyrate) accumulation in 33
Identification of nonhistone substrates of the lysine methyltransferase PRDM933
Abstract 1473: Modeling Binding of Beta-site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Aminoquinoline (68 K) for Possible Treatment of Alzheimer's Disease33
Abstract 2022: Regulation of Estrogen Receptor Signaling by FKBP52 in Breast Cancer Cells33
Abstract 1812: The Interplay of Acetylation and Ubiquitination33
Abstract 1517 Examining the effect of L-rhamnose metabolism on the transcriptome of Escherichia coli32
Abstract 1369 Harnessing plant specialized metabolism for new medicines through synthetic biology32
Abstract 1708 CTBP1 Mutation Affects Neuronal Stem Cell Migration32
Abstract 1370: How Selection Bias and Data Interpretation Contribute to Disparities in Health Outcomes and Artificial Intelligence Development32
Lipid biosynthesis perturbation impairs endoplasmic reticulum–associated degradation32
Abstract 1895 Educational Equity in a Community College Classroom - Using UR as a High Impact Practice Tool32
Abstract 1259 Biochemical Investigation and Evolutionary Comparison of the Mechanism of the Initiation of DNA Replication in Eukaryotic Cells32
Transportin 1 is a major nuclear import receptor of the nitric oxide synthase interacting protein32
Phosphorylation alters the mechanical stiffness of a model fragment of the dystrophin homologue utrophin32
Functionally redundant formate dehydrogenases enable formate-dependent growth in Methanococcus maripaludis32
Abstract 2006 Determining the Effects of Motif A Phosphorylation on SIRT1 Activity32
Abstract 1007 Novel Interactions of Potato Spindle Tuber Viroid RNA with Pokeweed Antiviral Protein32
Abstract 1165: Potential “Release-on-Demand” Metallopolymer Coatings For Drug-Release, Biofabrication, and In Vitro Experimental Control32
Abstract 1947 Exploring the Interplay of Social- Economic, and Racial Disparities Stress and Their Impact on Breast Cancer, with a Focus on Triple Negative Breast Cancer and Hormonal Imbalance-Induced32
Abstract 2374: MAP Kinase Phosphatases as Nodal Signal Regulators in Health and Disease31
Abstract 2178: Understanding TAOK1 dysfunction in neurodevelopmental disorders using human stem cell derived models31
Antimicrobial peptides selectively target malaria parasites by a cholesterol-dependent mechanism31
Enriched G4 forming repeats in the human genome are associated with robust well-coordinated transcription and reduced cancer transcriptome variation31
Artesunate enhances the efficacy of enzalutamide in advanced prostate cancer31
Abstract 1365: Interplay Between Nicotine, BDNF, and a β-Adrenergic Receptor Blocker in Regulating Cisplatin Resistance in Lung Cancer Cells31
Catalytically distinct metabolic enzyme isocitrate dehydrogenase 1 mutants tune phenotype severity in tumor models31
Natural and synthetic 2-oxoglutarate derivatives are substrates for oncogenic variants of human isocitrate dehydrogenase 1 and 231
Nonfunctional coq10 mutants maintain the ERMES complex and reveal true phenotypes associated with the loss of the coenzyme Q chaperone protein Coq1030
A bacterial actin with high ATPase activity regulates the polymerization of a partner MreB isoform essential for Spiroplasma swimming motility30
Histone acetyltransferase KAT2A modulates neural stem cell differentiation and proliferation by inducing degradation of the transcription factor PAX630
A conserved phosphorylation mechanism for regulating the interaction between the CMG replicative helicase and its forked DNA substrate30
The activity of the ribonucleotide monophosphatase UmpH is controlled by interaction with the GlnK signaling protein in Escherichia coli30
mRNA display reveals a class of high-affinity bromodomain-binding motifs that are not found in the human proteome30
Protein engineering of a nanoCLAMP antibody mimetic scaffold as a platform for producing bioprocess-compatible affinity capture ligands30
Human UFSP1 translated from an upstream near-cognate initiation codon functions as an active UFM1-specific protease30
A genus-specific nsp12 region impacts polymerase assembly in Alphacoronavirus and Gammacoronavirus30
Methionine cycle inhibition disrupts antioxidant metabolism and reduces glioblastoma cell survival30
Nesprin-2 is a novel scaffold protein for telethonin and FHL-2 in the cardiomyocyte sarcomere30
The two paralogous copies of the YoeB–YefM toxin–antitoxin module in Staphylococcus aureus differ in DNA binding and recognition patterns30
Characterization of a lytic polysaccharide monooxygenase from Aspergillus fumigatus shows functional variation among family AA11 fungal LPMOs30
The E3 ubiquitin ligase RNF126 facilitates quality control of unimported mitochondrial membrane proteins29
Targeting HNRNPA2B1 to overcome chemotherapy resistance in gastric cancer stem cells: Mechanisms and therapeutic potential29
Mutational and biophysical analyses reveal a TFIIIC binding region in the TFIIF-related Rpc53 subunit of RNA polymerase III29
The green ESCRTs: Newly defined roles for ESCRT proteins in plants29
A tribute to Sidney Altman, one of the architects of modern RNA biology29
Crystal structure and mechanistic studies of the PPM1D serine/threonine phosphatase catalytic domain29
Hhatl ameliorates endoplasmic reticulum stress through autophagy by associating with LC329
Redox imbalance induces remodeling of glucose metabolism in Rhipicephalus microplus embryonic cell line29
A biallelic variant of the RNA exosome gene, EXOSC4, associated with neurodevelopmental defects impairs RNA exosome function and translation29
Single-cell profiling identifies LIN28A mRNA targets in the mouse pluripotent-to-2C-like transition and somatic cell reprogramming29
Novel Z-DNA binding domains in giant viruses29
Binding with heat shock cognate protein HSC70 fine-tunes the Golgi association of the small GTPase ARL5B28
Combined inhibition of aurora kinases and Bcl-xL induces apoptosis through select BH3-only proteins28
Glial fibrillary acidic protein is pathologically modified in Alexander disease28
Pre-rRNA facilitates the recruitment of RAD51AP1 to DNA double-strand breaks28
The C-terminal domain of the antiamyloid chaperone DNAJB6 binds to amyloid-β peptide fibrils and inhibits secondary nucleation28
p53 regulates skeletal muscle mitophagy and mitochondrial quality control following denervation-induced muscle disuse28
Hepatocyte polarity establishment and apical lumen formation are organized by Par3, Cdc42, and aPKC in conjunction with Lgl28
Divergent allostery reveals critical differences between structurally homologous regulatory domains of Plasmodium falciparum and human protein kinase G28
Characterization of ribosome stalling and no-go mRNA decay stimulated by the fragile X protein, FMRP28
HRI protein kinase in cytoplasmic heme sensing and mitochondrial stress response: Relevance to hematological and mitochondrial diseases28
N-glycan antennal modifications are altered in Caenorhabditis elegans lacking the HEX-4 N-acetylgalactosamine-specific hexosaminidase28
Cannabinoid CB2 receptors are upregulated via bivalent histone modifications and control primary afferent input to the spinal cord in neuropathic pain28
Surface electrostatics dictate RNA-binding protein CAPRIN1 condensate concentration and hydrodynamic properties28
The development of a high-affinity conformation-sensitive antibody mimetic using a biocompatible copolymer carrier (iBody)28
Structural basis of membrane machines that traffick and attach heme to cytochromes28
Declining activity of serum response factor in aging aorta in relation to aneurysm progression28
Reconstitution of purified membrane protein dimers in lipid nanodiscs with defined stoichiometry and orientation using a split GFP tether28
Integrin mediates cell entry of the SARS-CoV-2 virus independent of cellular receptor ACE227
Endoplasmic reticulum protein BIK binds to and inhibits mitochondria-localized antiapoptotic proteins27
A recombinant technique for mapping functional sites of heterotrimeric collagen helices: Collagen IV CB3 fragment as a prototype for integrin binding27
The human autophagy-initiating complexes ULK1C and PI3KC3-C127
CLIC5A binds to and stabilizes the open and active conformation of ezrin27
The serine protease inhibitor HAMpin-1 produced by the ectoparasite Hyalomma anatolicum salivary gland modulates the host complement system27
Conversion of glutamate into proline by the leucine analog BCH enhances biphasic insulin secretion in pancreatic β-cells27
Argonaute 1 contributes to the transcriptional silencing of HIV-127
The permanently chaperone-active small heat shock protein Hsp17 from Caenorhabditis elegans exhibits topological separation of its N-terminal regions27
Cryo-EM structures reveal the PP2A–B55α and Eya3 interaction that can be disrupted by a peptide inhibitor27
Critical roles of protein disulfide isomerases in balancing proteostasis in the nervous system27
Structural and functional analysis of a bile salt hydrolase from the bison microbiome27
Cell targeting by the bicomponent leukocidin subunit HlgB drives Staphylococcus aureus pathophysiology27
C9orf72-associated dipeptide protein repeats form A11-positive oligomers in amyotrophic lateral sclerosis and frontotemporal dementia27
Purinosomes spatially co-localize with mitochondrial transporters27
The LDL receptor-related protein 1 (LRP1) facilitates ACE2-mediated endocytosis of SARS-CoV2 spike protein-containing pseudovirions27
In vivo analysis of Drosophila chondroitin sulfate biosynthetic genes27
A short-chain acyl-CoA synthetase that supports branched-chain fatty acid synthesis in Staphylococcus aureus27
Maternal obesity alters histone modifications mediated by the interaction between EZH2 and AMPK, impairing neural differentiation in the developing embryonic brain cortex27
A tumor microenvironment-activated metal-organic framework–based nanoplatform for amplified oxidative stress–induced enhanced chemotherapy27
The unique N-terminal region of Mycobacterium tuberculosis sigma factor A plays a dominant role in the essential function of this protein27
Exosome-mediated mRNA delivery in vivo is safe and can be used to induce SARS-CoV-2 immunity27
The Stathmin-2 membrane-targeting domain is required for axon protection and regulated degradation by DLK signaling27
Co-folding and RNA activation of poliovirus 3Cpro polyprotein precursors26
RNA-Seq reveals that overexpression of TcUBP1 switches the gene expression pattern toward that of the infective form of Trypanosoma cruzi26
Kinome profiling identifies MARK3 and STK10 as potential therapeutic targets in uveal melanoma26
The NADH recycling enzymes TsaC and TsaD regenerate reducing equivalents for Rieske oxygenase chemistry26
SUMOylation of the ubiquitin ligase component KEAP1 at K39 upregulates NRF2 and its target function in lung cancer cell proliferation26
Nucleation of fibronectin fibril assembly requires binding between heparin and the 13th type III module of fibronectin26
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