OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Biological Chemistry is 58. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
SARS-CoV-2 infects cells after viral entry via clathrin-mediated endocytosis	347
The SARS-CoV-2 envelope and membrane proteins modulate maturation and retention of the spike protein, allowing assembly of virus-like particles	219
Molnupiravir promotes SARS-CoV-2 mutagenesis via the RNA template	213
Antisense technology: A review	192
The essential elements of Alzheimer’s disease	170
The interplay of fibroblasts, the extracellular matrix, and inflammation in scar formation	156
Zinc transporters and their functional integration in mammalian cells	147
Recent advances in de novo protein design: Principles, methods, and applications	146
Major advances in targeted protein degradation: PROTACs, LYTACs, and MADTACs	136
Mitochondrial metabolism regulates macrophage biology	127
Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity	126
Template-dependent inhibition of coronavirus RNA-dependent RNA polymerase by remdesivir reveals a second mechanism of action	123
ZBP1 promotes fungi-induced inflammasome activation and pyroptosis, apoptosis, and necroptosis (PANoptosis)	110
Piezo1 acts upstream of TRPV4 to induce pathological changes in endothelial cells due to shear stress	110
The 89-kDa PARP1 cleavage fragment serves as a cytoplasmic PAR carrier to induce AIF-mediated apoptosis	108
The chaperone GRP78 is a host auxiliary factor for SARS-CoV-2 and GRP78 depleting antibody blocks viral entry and infection	105
Structural basis for the in vitro efficacy of nirmatrelvir against SARS-CoV-2 variants	103
1,6-Hexanediol, commonly used to dissolve liquid–liquid phase separated condensates, directly impairs kinase and phosphatase activities	103
Discovery of amivantamab (JNJ-61186372), a bispecific antibody targeting EGFR and MET	101
Deubiquitinating enzymes (DUBs): Regulation, homeostasis, and oxidative stress response	100
Unusual zwitterionic catalytic site of SARS–CoV-2 main protease revealed by neutron crystallography	99
Regulation and function of the mammalian tricarboxylic acid cycle	95
Seeing beyond the limit: A guide to choosing the right super-resolution microscopy technique	92
The spike protein of SARS-CoV-2 induces endothelial inflammation through integrin α5β1 and NF-κB signaling	91
The SARS-CoV-2 Y453F mink variant displays a pronounced increase in ACE-2 affinity but does not challenge antibody neutralization	89

From OCR and ECAR to energy: Perspectives on the design and interpretation of bioenergetics studies	88
SARS-CoV-2 viral budding and entry can be modeled using BSL-2 level virus-like particles	85
Exosome-mediated mRNA delivery in vivo is safe and can be used to induce SARS-CoV-2 immunity	84
Toward the solution of the protein structure prediction problem	83
High affinity binding of SARS-CoV-2 spike protein enhances ACE2 carboxypeptidase activity	80
Small molecule strategies to harness the unfolded protein response: where do we go from here?	79
Acidity and nucleophilic reactivity of glutathione persulfide	78
Exploring cellular biochemistry with nanobodies	75
The SARS-CoV-2 Nsp3 macrodomain reverses PARP9/DTX3L-dependent ADP-ribosylation induced by interferon signaling	74
Bacterial iron detoxification at the molecular level	74
Role of host factors in SARS-CoV-2 entry	73
Targeting mitophagy in Parkinson's disease	73
Presence of hyaluronan in lung alveoli in severe Covid-19: An opening for new treatment options?	72
Structure and function of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family: Tidying up diversity	68
Inhibition of acid sphingomyelinase by ambroxol prevents SARS-CoV-2 entry into epithelial cells	68
The m6A methyltransferase METTL3 modifies PGC-1α mRNA promoting mitochondrial dysfunction and oxLDL-induced inflammation in monocytes	68
Molecular mechanisms of telomere biology disorders	67
Structural analysis of carbohydrate binding by the macrophage mannose receptor CD206	67
Regulation of tau internalization, degradation, and seeding by LRP1 reveals multiple pathways for tau catabolism	65
Multiple variants of the fungal effector AVR-Pik bind the HMA domain of the rice protein OsHIPP19, providing a foundation to engineer plant defense	64
Priming of SARS-CoV-2 S protein by several membrane-bound serine proteinases could explain enhanced viral infectivity and systemic COVID-19 infection	64
Adaptation of influenza viruses to human airway receptors	64
There’s more to death than life: Noncatalytic functions in kinase and pseudokinase signaling	63
From structure to the dynamic regulation of a molecular switch: A journey over 3 decades	63
Genetic glycoengineering in mammalian cells	62
Phase separation by the SARS-CoV-2 nucleocapsid protein: Consensus and open questions	61
The binding of heparin to spike glycoprotein inhibits SARS-CoV-2 infection by three mechanisms	60
Update and nomenclature proposal for mammalian lysophospholipid acyltransferases, which create membrane phospholipid diversity	60
Ferroptosis drives photoreceptor degeneration in mice with defects in all-trans-retinal clearance	59
Mechanisms tailoring the expression of heat shock proteins to proteostasis challenges	59
Flagging fusion: Phosphatidylserine signaling in cell–cell fusion	59
From integrative structural biology to cell biology	58
Structure, mechanism, and regulation of mitochondrial DNA transcription initiation	58