Immunology

Article	Citations
New‐onset autoimmune phenomena post‐COVID‐19 vaccination	274
Immunopathological characteristics of coronavirus disease 2019 cases in Guangzhou, China	208
T‐cell responses and therapies against SARS‐CoV‐2 infection	152
Respiratory microbiome and epithelial interactions shape immunity in the lungs	99
Monocytes, macrophages, dendritic cells and neutrophils: an update on lifespan kinetics in health and disease	90
The early landscape of coronavirus disease 2019 vaccine development in the UK and rest of the world	75
Haemocyte‐mediated immunity in insects: Cells, processes and associated components in the fight against pathogens and parasites	71
Regulatory T‐cells in helminth infection: induction, function and therapeutic potential	67
Quantitative and qualitative alterations of circulating myeloid cells and plasmacytoid DC in SARS‐CoV‐2 infection	66
Cytokine‐regulated Th17 plasticity in human health and diseases	64
The NLRP6 inflammasome	54
New developments in our understanding of ankylosing spondylitis pathogenesis	54
Interleukin‐17 and ischaemic stroke	47
CCR8 marks highly suppressive Treg cells within tumours but is dispensable for their accumulation and suppressive function	46
The role of Bruton's tyrosine kinase in the immune system and disease	40
NK‐cell exhaustion, B‐cell exhaustion and T‐cell exhaustion—the differences and similarities	39
NLRP7: From inflammasome regulation to human disease	39
Why do intestinal epithelial cells express MHC class II?	38
Transient tear hyperosmolarity disrupts the neuroimmune homeostasis of the ocular surface and facilitates dry eye onset	38
Understanding the mechanisms that facilitate specificity, not redundancy, of chemokine‐mediated leukocyte recruitment	36
Inhibition of the NLRP3 inflammasome by HSP90 inhibitors	36
Candida albicans and candidalysin in inflammatory disorders and cancer	35
Interaction between intestinal microbiota and tumour immunity in the tumour microenvironment	34
Targeting immunometabolism in host defence against Mycobacterium tuberculosis	34
Endocannabinoids in immune regulation and immunopathologies	34

Itaconate and fumarate derivatives inhibit priming and activation of the canonical NLRP3 inflammasome in macrophages	32
M2 polarization of tumor‐associated macrophages is dependent on integrin β3 via peroxisome proliferator‐activated receptor‐γ up‐regulation in breast cancer	31
Neutrophil and remnant clearance in immunity and inflammation	31
Annexin A3 in sepsis: novel perspectives from an exploration of public transcriptome data	31
Tissue regulatory T cells	31
Human FOXP3 and tumour microenvironment	31
Macrophage reprogramming for therapy	29
NLR in eXile: Emerging roles of NLRX1 in immunity and human disease	29
Crosstalk between B cells and neutrophils in rheumatoid arthritis	29
Development of a high‐sensitivity ELISA detecting IgG, IgA and IgM antibodies to the SARS‐CoV‐2 spike glycoprotein in serum and saliva	28
Emerging roles of extracellular vesicles in COVID‐19, a double‐edged sword?	28
B2M gene expression shapes the immune landscape of lung adenocarcinoma and determines the response to immunotherapy	28
Neuromedin U: potential roles in immunity and inflammation	27
Viruses and asthma: the role of common respiratory viruses in asthma and its potential meaning for SARS‐CoV‐2	27
Neutrophil–T cell crosstalk in inflammatory bowel disease	26
Immunogenicity and safety of SpikoGen®, an adjuvanted recombinant SARS‐CoV‐2 spike protein vaccine as a homologous and heterologous booster vaccination: A randomized placebo‐controlled trial	26
The battle for iron in enteric infections	26
The liver as an immunological barrier redefined by single‐cell analysis	26
Single‐cell landscape and clinical outcomes of infiltrating B cells in colorectal cancer	26
Crosstalk between circadian rhythms and the microbiota	25
Retinal microglia: Functions and diseases	24
Oral microbiome interactions with gingival gene expression patterns for apoptosis, autophagy and hypoxia pathways in progressing periodontitis	24
Targeting metabolism to reverse T‐cell exhaustion in chronic viral infections	23
Enigmatic inflammasomes	23
IL‐36 cytokines and gut immunity	23
MHC class I transactivator NLRC5 in host immunity, cancer and beyond	23
The role of B cells in the immunopathogenesis of multiple sclerosis	22
Circles of Life: linking metabolic and epigenetic cycles to immunity	22
Neutrophils in pregnancy: New insights into innate and adaptive immune regulation	22
T‐cells producing multiple combinations of IFNγ, TNF and IL10 are associated with mild forms of dengue infection	21
T‐cells expressing a chimeric‐PD1‐Dap10‐CD3zeta receptor reduce tumour burden in multiple murine syngeneic models of solid cancer	21
Hypoxia‐inducible factor‐1 drives divergent immunomodulatory functions in the pathogenesis of autoimmune diseases	21
Siglec‐5 is an inhibitory immune checkpoint molecule for human T cells	20
Unknown/enigmatic functions of extracellular ASC	20
Differential immune responses of immunoglobulin Z subclass members in antibacterial immunity in a zebrafish model	20
IL‐33 activates mTORC1 and modulates glycolytic metabolism in CD8+ T cells	20
Regulation of CTLA‐4 recycling by LRBA and Rab11	20
Functional differentiation and regulation of follicular T helper cells in inflammation and autoimmunity	20
Cytoplasmic‐translocated Ku70 senses intracellular DNA and mediates interferon‐lambda1 induction	20
Insufficient CD100 shedding contributes to suppression of CD8+ T‐cell activity in non‐small cell lung cancer	20
Double‐negative T cells: Setting the stage for disease control or progression	19
HIV infection suppresses TLR3 activation‐mediated antiviral immunity in microglia and macrophages	19
The role of hydrogen sulphide signalling in macrophage activation	19
Our evolving view of neutrophils in defining the pathology of chronic lung disease	19
Landscape of variable domain of heavy‐chain‐only antibody repertoire from alpaca	19
Annexin‐A1: The culprit or the solution?	18
Vaccines, adjuvants and key factors for mucosal immune response	18
Depletion of langerin+ cells enhances cutaneous wound healing	18
CD8+ T cell exhaustion in anti‐tumour immunity: The new insights for cancer immunotherapy	18
The immune response to COVID‐19: Does sex matter?	18

Cell death as part of innate immunity: Cause or consequence?	18
Whole blood‐based measurement of SARS‐CoV‐2‐specific T cells reveals asymptomatic infection and vaccine immunogenicity in healthy subjects and patients with solid‐organ cancers	18
HLA‐DR polymorphism in SARS‐CoV‐2 infection and susceptibility to symptomatic COVID‐19	17
Selective serotonin reuptake inhibitor attenuates the hyperresponsiveness of TLR2+ and TLR4+ Th17/Tc17‐like cells in multiple sclerosis patients with major depression	17
Cellular landscape of tumour microenvironment in prostate cancer	17
Identifying SARS‐CoV‐2 ‘memory’ NK cells from COVID‐19 convalescent donors for adoptive cell therapy	17
Ectopic lymphoid follicles in progressive multiple sclerosis: From patients to animal models	17
LincRNA‐EPS alleviates severe acute pancreatitis by suppressing HMGB1‐triggered inflammation in pancreatic macrophages	17
ATP/IL‐33‐triggered hyperactivation of mast cells results in an amplified production of pro‐inflammatory cytokines and eicosanoids	16
The turning away of serum amyloid A biological activities and receptor usage	16
The roles of interleukin‐1 receptor accessory protein in certain inflammatory conditions	16
Immunological roles of intestinal mesenchymal cells	16
Schistosome and intestinal helminth modulation of macrophage immunometabolism	15
Interleukin‐33 alleviates psoriatic inflammation by suppressing the T helper type 17 immune response	15
The relationship between peripheral immune response and disease severity in SARS‐CoV‐2‐infected subjects: A cross‐sectional study	15
Advances in the study of CD47‐based bispecific antibody in cancer immunotherapy	15
Unboxing dendritic cells: Tales of multi‐faceted biology and function	15
NKG2A‐checkpoint inhibition and its blockade critically depends on peptides presented by its ligand HLA‐E	15
MicroRNA‐590‐3p inhibits T helper 17 cells and ameliorates inflammation in lupus mice	15
Generation of multiepitope cancer vaccines based on large combinatorial libraries of survivin‐derived mutant epitopes	15
Metabolic plasticity and regulation of T cell exhaustion	14
Stromal–immune cell crosstalk fundamentally alters the lung microenvironment following tissue insult	14
Update on the current knowledge of lymphatic drainage system and its emerging roles in glioma management	14
HLA‐dependent variation in SARS‐CoV‐2 CD8 + T cell cross‐reactivity with human coronaviruses	14
Immune response during hantavirus diseases: implications for immunotherapies and vaccine design	14
Alternative pathway dysregulation in tissues drives sustained complement activation and predicts outcome across the disease course in COVID‐19	14
Implications of cellular metabolism for immune cell migration	14
The immune response as a double‐edged sword: The lesson learnt during the COVID‐19 pandemic	14
Induction of the apoptosis, degranulation and IL‐13 production of human basophils by butyrate and propionate via suppression of histone deacetylation	14
Preselection TCR repertoire predicts CD4+ and CD8+ T‐cell differentiation state	13
Developing an immune‐related gene prognostic index associated with progression and providing new insights into the tumor immune microenvironment of prostate cancer	13
Age‐related changes in ocular mucosal tolerance: Lessons learned from gut and respiratory tract immunity	13
Ectopic endometriotic stromal cells‐derived lactate induces M2 macrophage polarization via Mettl3/Trib1/ERK/STAT3 signalling pathway in endometriosis	13
The developing immune network in human prenatal skin	13
Calcium controlled NFATc1 activation enhances suppressive capacity of regulatory T cells isolated from generalized vitiligo patients	13
A role for cell‐autocrine interleukin‐2 in regulatory T‐cell homeostasis	13
PTBP1 is necessary for dendritic cells to regulate T‐cell homeostasis and antitumour immunity	13
Ubiquitin E3 ligase MID1 inhibits the innate immune response by ubiquitinating IRF3	13
The role of high‐density lipoprotein in the regulation of the immune response: implications for atherosclerosis and autoimmunity	13
Thyrotrophin and thyroxine support immune homeostasis in humans	12
PAQR11 modulates monocyte‐to‐macrophage differentiation and pathogenesis of rheumatoid arthritis	12
Tacrolimus (FK506) treatment protects allergen‐, IL‐5‐ and IL‐13‐induced mucosal eosinophilia	12
Neuroimmune crosstalk and evolving pharmacotherapies in neurodegenerative diseases	12
Inducible ablation of CD11c+ cells to determine their role in skin wound repair	12
Hallmarks of NLRP3 inflammasome activation are observed in organotypic hippocampal slice culture	12
Complement activation by human IgG antibodies to galactose‐α‐1,3‐galactose	12
NLRP9 in innate immunity and inflammation	12
The glycobiology of uropathogenic E. coli infection: the sweet and bitter role of sugars in urinary tract immunity	12
The combinatorial diversity of KIR and HLA class I allotypes in Peninsular Malaysia	12
Effector immune cells in chronic lung allograft dysfunction: A systematic review	12
MicroRNA‐7 negatively regulates Toll‐like receptor 4 signaling pathway through FAM177A	12
Immunometabolism shapes B cell fate and functions	12
The role of O‐GlcNAcylation in immunity against infections	11
Non‐structural protein 1‐specific antibodies directed against Zika virus in humans mediate antibody‐dependent cellular cytotoxicity	11
TIM3/CEACAM1 pathway involves in myeloid‐derived suppressor cells induced CD8+ T cells exhaustion and bone marrow inflammatory microenvironment in myelodysp	11
Recent developments in immunotherapy of cancers caused by human papillomaviruses	11
Nanoparticle‐mediated targeting of autoantigen peptide to cross‐presenting liver sinusoidal endothelial cells protects from CD8 T‐cell‐driven autoimmune cholangitis	11
Heterogeneous cancer‐associated fibroblasts: A new perspective for understanding immunosuppression in pancreatic cancer	11
NLR family pyrin domain containing 3 (NLRP3) and caspase 1 (CASP1) modulation by intracellular Cl– concentration	11
The paradoxical role of radiation‐induced cGAS–STING signalling network in tumour immunity	10
IL‐20 is involved in obesity by modulation of adipogenesis and macrophage dysregulation	10
Improved prediction of HLA antigen presentation hotspots: Applications for immunogenicity risk assessment of therapeutic proteins	10
Elucidating host–microbe interactions in vivo by studying population dynamics using neutral genetic tags	10
Role of CD14 in human disease	10
Interdependencies between Toll‐like receptors in Leishmania infection	10
Macrophage metabolism in the intestine is compartment specific and regulated by the microbiota	10
Neutrophils in secondary lymphoid organs	10
Suppression of airway allergic eosinophilia by Hp‐TGM, a helminth mimic of TGF‐β	10
Characterizing the original anti‐C5 function‐blocking antibody, BB5.1, for species specificity, mode of action and interactions with C5	10
Preclinical models for studying immune responses to traumatic injury	10
Transcriptomic profiling of cardiac tissues from SARS‐CoV‐2 patients identifies DNA damage	10
Anti‐tumour potential of PD‐L1/PD‐1 post‐translational modifications	10
Development of novel reagents to chicken FLT3, XCR1 and CSF2R for the identification and characterization of avian conventional dendritic cells	9
Multi‐responsive mesoporous polydopamine composite nanorods cooperate with nano‐enzyme and photosensitiser for intensive immunotherapy of bladder cancer	9
Glycans as shapers of tumour microenvironment: A sweet driver of T‐cell‐mediated anti‐tumour immune response	9
Epigenetics: An opportunity to shape innate and adaptive immune responses	9
The cytotoxic molecule granulysin is capable of inducing either chemotaxis or fugetaxis in dendritic cells depending on maturation: a role for Vδ2+γδ T cells in the modulation	9
Human CD36hi monocytes induce Foxp3+ CD25+ T cells with regulatory functions from CD4 and CD8 subsets	9
p38 MAPK signaling mediates retinoic acid‐induced CD103 expression in human dendritic cells	9
Diabetes and susceptibility to infections: Implication for COVID‐19	9

Targeting glycolysis in Th2 cells by pterostilbene attenuates clinical severities in an asthmatic mouse model and IL‐4 production in peripheral blood from asthmatic patients	8
Immunomodulatory functions of TRPM7 and its implications in autoimmune diseases	8
Neutralizing interferon‐α blocks inflammation‐mediated vascular injury via PI3K and AMPK in systemic lupus erythematosus	8
Cell origin and niche availability dictate the capacity of peritoneal macrophages to colonize the cavity and omentum	8
CD11c participates in triggering acute graft‐versus‐host disease during bone marrow transplantation	8
Heat inactivated mycobacteria, alpha‐Gal and zebrafish: Insights gained from experiences with two promising trained immunity inductors and a validated animal model	8
Biological functions of IL‐17‐producing cells in mycoplasma respiratory infection	8
The kinetics of IgG subclasses and contributions to neutralizing activity against SARS‐CoV‐2 wild‐type strain and variants in healthy adults immunized with inactivated vaccine	8
A comprehensive review of IL‐26 to pave a new way for a profound understanding of the pathobiology of cancer, inflammatory diseases and infections	8
Quantifying immunoregulation by autoantigen‐specific T‐regulatory type 1 cells in mice with simultaneous hepatic and extra‐hepatic autoimmune disorders	8
Gasdermin D‐independent release of interleukin‐1β by living macrophages in response to mycoplasmal lipoproteins and lipopeptides	8
Comparison of the immunogenicity of five COVID‐19 vaccines in Sri Lanka	8
Mononuclear phagocyte regulation by the transcription factor Blimp‐1 in health and disease	8
The UK Veterinary Immunological Toolbox Website: promoting vaccine research by facilitating communication and removing reagent barriers	8
The human natural anti‐αGal antibody targets common pathogens by broad‐spectrum polyreactivity	8
The role of HMGB1 in COVID‐19‐induced cytokine storm and its potential therapeutic targets: A review	8
Metabolic manipulation of the tumour immune microenvironment	8
TLR5 activation in hepatocytes alleviates the functional suppression of intrahepatic CD8+ T cells	8
Adoptive transfer of IL‐4 reprogrammed Tc17 cells elicits anti‐tumour immunity through functional plasticity	7
Metabolomic and lipidomic signatures associated with activation of human cDC1 (BDCA3+/CD141+) dendritic cells	7
Histone hyperacetylation mediates enhanced IL‐1β production in LPS/IFN‐γ‐stimulated macrophages	7
Immune responses to Sinopharm/BBIBP‐CorV in individuals in Sri Lanka	7
Tumour‐associated antigenic peptides are present in the HLA class I ligandome of cancer cell line derived extracellular vesicles	7
Immunological partners: the gut microbiome in homeostasis and disease	7
Glycogen synthase kinase‐3 promotes T helper type 17 differentiation by promoting interleukin‐9 production	7
Dynamic intron retention modulates gene expression in the monocytic differentiation pathway	7
T‐cell exhaustion in CAR‐T‐cell therapy and strategies to overcome it	7
Variation in genes implicated in B‐cell development and antibody production affects susceptibility to pemphigus	7
Reimagining laboratory‐based immunology education in the time of COVID‐19	7
Staphylococcus aureus controls eicosanoid and specialized pro‐resolving mediator production via lipoteichoic acid	7
Hepatocyte CD1d protects against liver immunopathology in mice with schistosomiasis japonica	7
Transcriptomic landscape of skin lesions in cutaneous leishmaniasis reveals a strong CD8+ T cell immunosenescence signature linked to immunopathology	7
Fc Fragment of IgE Receptor Ig (FCER1G) acts as a key gene involved in cancer immune infiltration and tumour microenvironment	7
Pathogenetic role and clinical significance of interleukin‐1β in cancer	7
TLR2 dimer‐specific ligands selectively activate protein kinase C isoforms in Leishmania infection	7
Interferon regulatory factor 4 deficiency in CD8+ T cells abrogates terminal effector differentiation and promotes transplant acceptance	7
ADP‐ribosylation in evasion, promotion and exacerbation of immune responses	7
Cytoskeleton protein 4.1R regulates B‐cell fate by modulating the canonical NF‐κB pathway	7
T cell‐intrinsic miR‐155 is required for Th2 and Th17‐biased responses in acute and chronic airway inflammation by targeting several different transcription factors	7
Role of myeloid cells in the regulation of group 2 innate lymphoid cell‐mediated allergic inflammation	7
Epithelial cell‐derived CD83 restores immune tolerance in the airway mucosa by inducing regulatory T‐cell differentiation	6
Dual effect of IL‐7/IL‐7R signalling on the osteoimmunological system: a potential therapeutic target for rheumatoid arthritis	6
The role of neuraminidase in TLR4‐MAPK signalling and the release of cytokines by lupus serum‐stimulated mesangial cells	6
Therapeutic antibody glycosylation impacts antigen recognition and immunogenicity	6
Comparison of HLA ligand elution data and binding predictions reveals varying prediction performance for the multiple motifs recognized by HLA‐DQ2.5	6
Ability of SpikoGen®, an Advax‐CpG adjuvanted recombinant spike protein vaccine, to induce cross‐neutralising antibodies against SARS‐CoV‐2 variants	6
Stem cell factor/mast cell/CCL2/monocyte/macrophage axis promotes Coxsackievirus B3 myocarditis and cardiac fibrosis by increasing Ly6Chigh monocyte influx and fibroge	6
Distinct antigen uptake receptors route to the same storage compartments for cross‐presentation in dendritic cells	6
NR4A1 mediates NK‐cell dysfunction in hepatocellular carcinoma via the IFN‐γ/p‐STAT1/IRF1 pathway	6
Tbet promotes CXCR6 expression in immature natural killer cells and natural killer cell egress from the bone marrow	6
The functional diversity of tissue‐resident natural killer cells against infection	6
Distinct responses of human peripheral blood cells to different misfolded protein oligomers	6
Metabolic mediators: How immunometabolism directs the immune response to infection	6
A lesson from the wild: The natural state of eosinophils is Ly6Ghi	6
Post‐transplant cyclophosphamide limits reactive donor T cells and delays the development of graft‐versus‐host disease in a humanized mouse model	6
The cytosolic tryparedoxin peroxidase from Trypanosoma cruzi induces a pro‐inflammatory Th1 immune response in a peroxidatic cysteine‐dependent manner	6
Treatment with IgM‐enriched intravenous immunoglobulins enhances clearance of stroke‐associated bacterial lung infection	6
Application of adoptive cell therapy in hepatocellular carcinoma	6
Characterization of age‐associated B cells in early drug‐naïve rheumatoid arthritis patients	6
Interleukin‐35 is a critical regulator of immunity during helminth infections associated with multiple sclerosis	6
1,25‐Dihydroxyvitamin D3 suppresses CD4+ T‐cell effector functionality by inhibition of glycolysis	6
Interferon‐α promotes MHC I antigen presentation of islet β cells through STAT1‐IRF7 pathway in type 1 diabetes	6
The clinical relevance of epithelial‐mesenchymal transition and its correlations with tumorigenic immune infiltrates in hepatocellular carcinoma	6
Metabolic regulators of enigmatic inflammasomes in autoimmune diseases and crosstalk with innate immune receptors	6
USP12 positively regulates M‐MDSC function to inhibit antitumour immunity through deubiquitinating and stabilizing p65	6
Prostaglandin E2 directly inhibits the conversion of inducible regulatory T cells through EP2 and EP4 receptors via antagonizing TGF‐β signalling	6
A behind‐the‐scenes tour of the IEDB curation process: an optimized process empirically integrating automation and human curation efforts	6
Identification of neoantigens in oesophageal adenocarcinoma	6
Stress hormone signalling inhibits Th1 polarization in a CD4 T‐cell‐intrinsic manner via mTORC1 and the circadian gene PER1	5
Complement: Functions, location and implications	5
Multi‐omic and spatial dissection of immunotherapy response groups in non‐small cell lung cancer	5
Elevated interleukin‐6, interleukin‐10 and neutrophil : lymphocyte ratio as identifiers of severe coronavirus disease 2019	5
Caspase‐6 is a key regulator of cross‐talk signal way in PANoptosis in cancer	5
Montelukast alleviates inflammation in experimental autoimmune encephalomyelitis by altering Th17 differentiation in a mouse model	5
Dopaminergic inhibition of human neutrophils is exerted through D1‐like receptors and affected by bacterial infection	5
Immunotherapeutic targets in non‐small cell lung cancer	5
Zoledronate promotes inflammatory cytokine expression in human CD14‐positive monocytes among peripheral mononuclear cells in the presence of γδ T cells	5
Temporal overexpression of IL‐22 and Reg3γ differentially impacts the severity of experimental autoimmune encephalomyelitis	5
Dysfunctional phenotype of systemic and pulmonary regulatory T cells associate with lethal COVID‐19 cases	5
Influence of chronic stress on the mechanism of the cytotoxic system in common carp (Cyprinuscarpio)	5
Pouring petrol on the flames: Using oncolytic virotherapies to enhance tumour immunogenicity	5
Effect of gut flora mediated‐bile acid metabolism on intestinal immune microenvironment	5
Distinct activities of Vδ1+ T‐cells upon different cytomegalovirus reactivation status after haematopoietic transplantation	5
Rabaptin5 acts as a key regulator for Rab7l1‐mediated phagosome maturation process	5
An immunogenetic investigation of 30 autoimmune and autoinflammatory diseases and their links to psychiatric disorders in a nationwide sample	5
Oxidative phosphorylation regulates interleukin‐10 production in regulatory B cells via the extracellular signal‐related kinase pathway	5
IgA binds to the AD‐2 epitope of glycoprotein B and neutralizes human cytomegalovirus	5
Critical roles of the E3 ubiquitin ligase FBW7 in B‐cell response and the pathogenesis of experimental autoimmune arthritis	5
Adhesion molecule cross‐linking and cytokine exposure modulate IgE‐ and non‐IgE‐dependent basophil activation	5
Development of novel self‐assembled vaccines based on tumour‐specific antigenic peptide and TLR2 agonist for effective breast cancer immunotherapy via activating CD8+ T cells and enhancing	5
Ataxia telangiectasia mutated kinase inhibition promotes irradiation‐induced PD‐L1 expression in tumour‐associated macrophages through IFN‐I/JAK signalling	5
IL‐3 is essential for ICOS‐L stabilization on mast cells, and sustains the IL‐33‐induced RORγt+ Treg generation via enhanced IL‐6 induction	5
Skin antigen‐presenting cells and wound healing: New knowledge gained and challenges encountered using mouse depletion models	5
LncRNA00492 is required for marginal zone B‐cell development	4
Aging is accompanied by T‐cell stiffening and reduced interstitial migration through dysfunctional nuclear organization	4