Immunology

Article	Citations
Human CD36hi monocytes induce Foxp3+ CD25+ T cells with regulatory functions from CD4 and CD8 subsets	333
NLRP7: From inflammasome regulation to human disease	113
Induction of the apoptosis, degranulation and IL‐13 production of human basophils by butyrate and propionate via suppression of histone deacetylation	99
Heat inactivated mycobacteria, alpha‐Gal and zebrafish: Insights gained from experiences with two promising trained immunity inductors and a validated animal model	72
Thyrotrophin and thyroxine support immune homeostasis in humans	57
A new strategy for immunotherapy of microsatellite‐stable (MSS)‐type advanced colorectal cancer: Multi‐pathway combination therapy with PD‐1/PD‐L1 inhibitors	57
Immune response during hantavirus diseases: implications for immunotherapies and vaccine design	56
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Editorial: Perspectives on the landscape of immunology from Nikhil Joshi	50
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Keap1 moderates the transcription of virus induced genes through G9a‐GLP and NFκB p50 recruitment	42
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The diversity of the plasmablast signature across species and experimental conditions: A meta‐analysis	37
Comparison of the immunogenicity of five COVID‐19 vaccines in Sri Lanka	35
CD57 T cells associated with immunosenescence in adults living with HIV or AIDS	35
Retinal microglia: Functions and diseases	33
Anti‐ and pro‐inflammatory milieu differentially regulate differentiation and immune functions of oligodendrocyte progenitor cells	31
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1,25‐Dihydroxyvitamin D3 suppresses CD4+ T‐cell effector functionality by inhibition of glycolysis	30
Effector Th1 cells under PD‐1 and CTLA‐4 checkpoint blockade abrogate the upregulation of multiple inhibitory receptors and by‐pass exhaustion	29
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Transforming growth factor‐β, Interleukin‐23 and interleukin‐1β modulate TH22 response during active multidrug‐resistant tuberculosis	29

A ‘waste product’ to save the day in the field of transplantation: The evolving potential of extracellular vesicles	27
Non‐structural protein 1‐specific antibodies directed against Zika virus in humans mediate antibody‐dependent cellular cytotoxicity	26
Monocyte pathology in human tuberculosis is due to plasma milieu changes and aberrant STAT signalling	26
Sialic acid in the regulation of blood cell production, differentiation and turnover	25
The TRIF‐RIPK1‐Caspase‐8 signalling in the regulation of TLR4‐driven gene expression	25
Mycobacterium vaccae alleviates allergic airway inflammation and airway hyper‐responsiveness in asthmatic mice by altering intestinal microbiota	25
Modified recombinant human IgG1‐Fc is superior to natural intravenous immunoglobulin at inhibiting immune‐mediated demyelination	25
Unboxing dendritic cells: Tales of multi‐faceted biology and function	25
Thymic atrophy creates holes in Treg‐mediated immuno‐regulation via impairment of an antigen‐specific clone	24
Immunological evidence of an early seroconversion to oncogenic Merkel cell polyomavirus in healthy children and young adults	23
Age‐related changes in ocular mucosal tolerance: Lessons learned from gut and respiratory tract immunity	23
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Lung adenocarcinoma manifesting as subsolid nodule potentially represents tumour in the equilibrium phase of immunoediting	21
IL‐2 amplifies quantitative TCR signalling inputs to drive Th1 and Th2 differentiation	20
LncRNA00492 is required for marginal zone B‐cell development	20
Single‐cell RNA sequencing reveals the altered innate immunity in immune checkpoint inhibitor‐related myocarditis	20
High common‐γ cytokine receptor levels promote expression of Interleukin‐2/Interleukin‐7 receptor α‐chains with implications on T‐cell differentiation and function	20
Conditional knockout of oestrogen receptor alpha in CD11c+ cells impacts female survival and inflammatory cytokine profile in murine lupus	20
Homotherapy for heteropathy: Interleukin‐41 and its biological functions	20
Taurine promotes B‐cell activation by interaction with the VH/VL framework regions of B‐cell receptor	20
Icariin alleviates oxygen‐induced retinopathy by targeting microglia hexokinase 2	20
Adenosine 2A receptor antagonists promote lymphocyte proliferation in sepsis by inhibiting Treg expression of PD‐L1 in spleen	19
Enigmatic inflammasomes – Sequel (Part 2)	19
Pathogenetic role and clinical significance of interleukin‐1β in cancer	18
Chimerism of avian IgY‐scFv and truncated IgG‐Fc: A novel strategy in cross‐species antibody generation and enhancement	18
Staphylococcus aureus biofilm properties and chronic rhinosinusitis severity scores correlate positively with total CD4+ T‐cell frequencies and inversely with its Th1, Th1	18
Myeloid‐derived suppressor cells from tumour‐bearing mice induce the population expansion of CD19hiFcγRIIbhi regulatory B cells via PD‐L1	18
Vaccines, adjuvants and key factors for mucosal immune response	17
The glycobiology of uropathogenic E. coli infection: the sweet and bitter role of sugars in urinary tract immunity	17
Deubiquitinase inhibitor PR‐619 potentiates colon cancer immunotherapy by inducing ferroptosis	17
Chromatin‐binding deubiquitinase MYSM1 acts in haematopoietic progenitors to control dendritic cell development and to program dendritic cell responses to microbial stimulation	17
New Engineered‐Chimeric Botulinum Neurotoxin Mutant Acts as an Effective Bivalent Vaccine Against Botulinum Neurotoxin Serotype A and E	17
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Editorial: Highlighting early‐career researchers—The future of Immunology	16
K33 only mutant ubiquitin augments bone marrow‐derived dendritic cell‐mediated CTL priming via PI3K‐Akt pathway	16
PKCζ activation promotes maturation of cord blood T cells towards a Th1 IFN‐γ propensity	16
Alternative pathway dysregulation in tissues drives sustained complement activation and predicts outcome across the disease course in COVID‐19	16
Role of airway epithelium in viral respiratory infections: Can carbocysteine prevent or mitigate them?	16
Local and systemic effects of IDH mutations on primary glioma patients	15
Unravelling CD4+ T cell diversity and tissue adaptation of Tregs in abdominal aortic aneurysms through single‐cell sequencing	15
Therapeutic antibody glycosylation impacts antigen recognition and immunogenicity	15
Hypoxic tumour‐derived exosomal miR‐1290 exacerbates the suppression of CD8+ T cells by promoting M2 macrophage polarization	15
FOXP3 Transcriptionally Activates Fatty Acid Scavenger Receptor CD36 in Tumour‐Induced Treg Cells	14
Adenosine signalling in T‐cell activation favours development of IL‐17 positive cells with suppressive properties	14
Update on the current knowledge of lymphatic drainage system and its emerging roles in glioma management	14
Advances in the study of CD47‐based bispecific antibody in cancer immunotherapy	14

Stromal–immune cell crosstalk fundamentally alters the lung microenvironment following tissue insult	14
Itaconate and fumarate derivatives inhibit priming and activation of the canonical NLRP3 inflammasome in macrophages	14
The role of high‐density lipoprotein in the regulation of the immune response: implications for atherosclerosis and autoimmunity	14
NRP1 downregulation correlates with enhanced ILC2 responses during IL‐33 challenge	14
Dynamic intron retention modulates gene expression in the monocytic differentiation pathway	13
mTORC2 contributes to systemic autoimmunity	13
Non‐fitness status of peripheral NK cells defined by decreased NKp30 and perforin, and increased soluble B7H6, in cervical cancer patients	13
Effect of gut flora mediated‐bile acid metabolism on intestinal immune microenvironment	13
Post‐transcriptional control of T‐cell cytokine production: Implications for cancer therapy	13
The immune response to COVID‐19: Does sex matter?	13
The hippo kinase MST1 negatively regulates the differentiation of follicular helper T cells	13
Effectiveness of interleukin‐4 administration or zinc supplementation in improving zinc deficiency–associated thymic atrophy and fatty degeneration and in normalizing T cell maturation process	13
Glycans as shapers of tumour microenvironment: A sweet driver of T‐cell‐mediated anti‐tumour immune response	12
Aging is accompanied by T‐cell stiffening and reduced interstitial migration through dysfunctional nuclear organization	12
Distinct responses of human peripheral blood cells to different misfolded protein oligomers	12
Advancements in Nipah virus treatment: Analysis of current progress in vaccines, antivirals, and therapeutics	12
Interferon‐α promotes MHC I antigen presentation of islet β cells through STAT1‐IRF7 pathway in type 1 diabetes	12
Circular RNA ACTR2 activates M2 polarization of macrophages through activating Yes‐associated protein signalling and contributes to renal fibrosis	12
Tumour necrosis factor plays a deleterious role in the pathogenesis of chikungunya virus infection	12
Comparison of culture media reveals that non‐essential amino acids strongly affect the phenotype of human monocyte‐derived macrophages	12
Roles of S100A8, S100A9 and S100A12 in infection, inflammation and immunity	12
Diabetes and susceptibility to infections: Implication for COVID‐19	12
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Circadian rhythm regulation in the immune system	11
Prognostic biomarkers associated with immune checkpoint inhibitors in hepatocellular carcinoma	11
COVID‐19 vaccination and treatment in vulnerable populations	11
Mycobacterium potentiates protection from colorectal cancer by gut microbial alterations	11
High TSLP responses in the human infant airways are associated with pre‐activated airway epithelial IFN antiviral immunity	11
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We need to talk about neutrophils	11
IL‐36 cytokines and gut immunity	11
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Pouring petrol on the flames: Using oncolytic virotherapies to enhance tumour immunogenicity	10
Serum vitamin D deficiency is associated with increased risk of γδ T cell exhaustion in HBV‐infected patients	10
Caspase‐6 is a key regulator of cross‐talk signal way in PANoptosis in cancer	10
Targeting PI3Kα increases the efficacy of anti‐PD‐1 antibody in cervical cancer	10
Soluble programmed death ligand‐1‐induced immunosuppressive effects on chimeric antigen receptor‐natural killer cells targeting Glypican‐3 in hepatocellular carcinoma	10
The immunoregulatory role of IL‐35 in patients with interstitial lung disease	10
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Impairment of Gal‐9 and Tim‐3 crosstalk between Tregs and Th17 cells drives tobacco smoke‐induced airway inflammation	9
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Macrophage memory: Types, mechanisms, and its role in health and disease	9
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Luminal bacteria coated with IgA and IgG during intestinal inflammation as a new and abundant stimulus for colonic macrophages	9
Glycans in melanoma: Drivers of tumour progression but sweet targets to exploit for immunotherapy	9
MicroRNA‐590‐3p inhibits T helper 17 cells and ameliorates inflammation in lupus mice	9
Goblet cell‐associated antigen passage: A gatekeeper of the intestinal immune system	9
CD11c participates in triggering acute graft‐versus‐host disease during bone marrow transplantation	9
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Anti‐tumour potential of PD‐L1/PD‐1 post‐translational modifications	9
Dual blockages of a broad and potent neutralizing IgM antibody targeting GH loop of EV‐As	9
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The origin of regulatory from the effector cells in LAG‐3‐marked Th1 immunity against severe influenza virus infection	8
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Probiotic Bacillus spp. enhance TLR3‐mediated TNF signalling in macrophages	8
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Distinct contributions of the innate immune receptors TLR2 and RP105 to formation and architecture of structured lung granulomas in mice infected with Mycobacterium tuberculos	8
Transcriptomic landscape of skin lesions in cutaneous leishmaniasis reveals a strong CD8+ T cell immunosenescence signature linked to immunopathology	8
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What's in a name? Nomenclature in immunology	8
TLR7 enhancing follicular helper T (Tfh) cells response in C57BL/6 mice infected with Plasmodium yoeliiNSM TLR7 mediated Tfh cells in P	8
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Comparison of the oncolytic activity of a replication‐competent and a replication‐deficient herpes simplex virus 1	8
B‐cell follicles in tuberculous lung: Active defenders or modest bystanders?	8
Dual effect of IL‐7/IL‐7R signalling on the osteoimmunological system: a potential therapeutic target for rheumatoid arthritis	8
New role of gramicidin A in RIG‐I‐like receptors‐mediated IFN signalling	7
Inactivation of mitochondrial pyruvate carrier promotes NLRP3 inflammasome activation and gout development via metabolic reprogramming	7
The role of HMGB1 in COVID‐19‐induced cytokine storm and its potential therapeutic targets: A review	7
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Activating receptor KIR2DS2 bound to HLA‐C1 reveals the novel recognition features of activating receptor	7
Natural killer cells promote intra‐cellular‐infected trophoblasts survival via APOD‐LRP1 axis	7
Dynamics of T follicular helper cells in patients with rheumatic diseases and subsequent antibody responses in a three‐dose immunization regimen of CoronaVac	7
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IL‐6 Signalling to Responding T Cells Is Key to Calcitonin Gene‐Related Peptide‐Exposed Endothelial Cell Enhancement of Th17 Immunity During Langerhans Cell Antigen Presentation	7

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Prophylactic Peanut Allergen Ara h 6 Sublingual Immunotherapy Drives Expansion of FoxP3+Helios− Regulatory T Cells in the Absence of Allergen‐Specific IgA	7
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cGAS modulates cytokine secretion and bacterial burdens by altering the release of mitochondrial DNA in pseudomonas pulmonary infection	7
The lack of either IRF9, or STAT2, has surprisingly little effect on human natural killer cell development and function	7
Blocking Deoxycytidine Kinase in Activated Lymphocytes Depletes Deoxycytidine Triphosphate Pools and Alters Cell Cycle Kinetics to Yield Less Disease in a Mouse Multiple Sclerosis Model	7
IRF5 Controls Plasma Cell Generation and Antibody Production via Distinct Mechanisms Depending on the Antigenic Trigger	7
Idiotopes of antibodies against HIV‐1 CD4‐induced epitope shared with those against microorganisms	6
Theories of immune recognition: Is anybody right?	6
Metabolic manipulation of the tumour immune microenvironment	6
Immunometabolism shapes B cell fate and functions	6
Induction of a cytokine storm involves suppression of the Osteopontin‐dependent TH1 response	6
Identification of different functions of CD8+ T cell subpopulations by a novel monoclonal antibody	6
The relationship between peripheral immune response and disease severity in SARS‐CoV‐2‐infected subjects: A cross‐sectional study	6
βhCG mediates immune suppression through upregulation of CD11b+Gr1+ myeloid derived suppressor cells, CD206+M2 macrophages,	6
NLRP2 in health and disease	6
Ubiquitin E3 ligase MID1 inhibits the innate immune response by ubiquitinating IRF3	6
B2M gene expression shapes the immune landscape of lung adenocarcinoma and determines the response to immunotherapy	6
New‐onset autoimmune phenomena post‐COVID‐19 vaccination	6
The red blood cell as a novel regulator of human B‐cell activation	6
Immunogenicity and safety of SpikoGen®, an adjuvanted recombinant SARS‐CoV‐2 spike protein vaccine as a homologous and heterologous booster vaccination: A randomized placebo‐controlled trial	6
Development of novel self‐assembled vaccines based on tumour‐specific antigenic peptide and TLR2 agonist for effective breast cancer immunotherapy via activating CD8+ T cells and enhancing	6
Calcium controlled NFATc1 activation enhances suppressive capacity of regulatory T cells isolated from generalized vitiligo patients	6
Suppression of airway allergic eosinophilia by Hp‐TGM, a helminth mimic of TGF‐β	6
Prevention and treatment of HPV‐related cancer through a mRNA vaccine expressing APC‐targeting antigen	6
Leishmania surface molecule lipophosphoglycan‐TLR2 interaction moderates TPL2‐mediated TLR2 signalling for parasite survival	6
Embedding of exogenous B cell epitopes on the surface of UreB structure generates a broadly reactive antibody response against Helicobacter pylori	5
Whole blood‐based measurement of SARS‐CoV‐2‐specific T cells reveals asymptomatic infection and vaccine immunogenicity in healthy subjects and patients with solid‐organ cancers	5
Role of CD14 in human disease	5
Aspergillus fumigatus‐derived gliotoxin impacts innate immune cell activation through modulating lipid mediator production in macrophages	5
Hydroxychloroquine attenuates double‐stranded RNA‐stimulated hyper‐phosphorylation of tristetraprolin/ZFP36 and AU‐rich mRNA stabilization	5
Unravelling CD24‐Siglec‐10 pathway: Cancer immunotherapy from basic science to clinical studies	5
Developing an immune‐related gene prognostic index associated with progression and providing new insights into the tumor immune microenvironment of prostate cancer	5
Inducible ablation of CD11c+ cells to determine their role in skin wound repair	5
Regulation of CTLA‐4 recycling by LRBA and Rab11	5
Trispecific antibodies for cancer immunotherapy	5
Contributions of each of the BAFF receptors to the lymphocyte profiles in C57BL/6 mice	5
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CD8+ T cell exhaustion in anti‐tumour immunity: The new insights for cancer immunotherapy	5
Adoptive transfer of IL‐4 reprogrammed Tc17 cells elicits anti‐tumour immunity through functional plasticity	5
Influence of chronic stress on the mechanism of the cytotoxic system in common carp (Cyprinuscarpio)	5
TREM1/DAP12 based novel multiple chain CAR‐T cells targeting DLL3 show robust anti‐tumour efficacy for small cell lung cancer	5
DNA methylation trajectories during innate and adaptive immune responses of human B lymphocytes	5
Identification of psoriasis‐associated immune marker G3BP2 through single‐cell RNA sequencing and meta analysis	5
Mast cells contribute to T‐cell accumulation in the bronchoalveolar space in mice with IL‐33‐induced airway inflammation	5
Fc Fragment of IgE Receptor Ig (FCER1G) acts as a key gene involved in cancer immune infiltration and tumour microenvironment	5
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Regulation of SETD2 maintains immune regulatory function in macrophages to suppress airway allergy	4
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Editorial: Streamlining the process of submissions to Immunology	4
Activated invariant natural killer T cells infiltrate aortic tissue as key participants in abdominal aortic aneurysm pathology	4
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CTLA4Ig/VISTAIg combination therapy selectively induces CD4+ T cell‐mediated immune tolerance by targeting the SOCS1 signaling pathway in porcine islet xenotransplantation	4
FcγRIIb protects from reperfusion injury by controlling antibody and type I IFN‐mediated tissue injury and death	4
Burnout in science	4
Early life vaccination reprograms the metabolism and function of myeloid cells in neonates	4
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Application of adoptive cell therapy in hepatocellular carcinoma	4
Antibodies to SARS‐CoV‐2 in patients with primary immunodeficiencies treated with nonspecific immunoglobulins	4
Correction to “Psychological stress to ovalbumin peptide‐specific T‐cell receptor transgenic mice impairs the suppressive ability of type 1 regulatory T cell”	4
Oncolytic virus treatment differentially affects the CD56dim and CD56bright NK cell subsets in vivo and regulates a spectrum of human NK cell activity	4
Memory CD8+ T cells exhibit tissue imprinting and non‐stable exposure‐dependent reactivation characteristics following blood‐stage Plasmodium berghei ANKA infections	4
Assessment of IgG‐Fc glycosylation from individual RhD‐specific B cell clones reveals regulation at clonal rather than clonotypic level	4
The alterations of innate immunity and enhanced severity of infections in diabetes mellitus	4
PD‐1 expression on tumour‐infiltrating cells is a prognostic factor for relapsed or refractory diffuse large B‐cell lymphoma	4
Beyond cytokines: Influences of the endocrine system on human immune homeostasis	4
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T cell maturation is significantly affected by SARS‐CoV‐2 infection	4
Immunopathology in human pulmonary tuberculosis: Inflammatory changes in the plasma milieu and impaired host immune cell functions	4
NLR family pyrin domain containing 3 (NLRP3) and caspase 1 (CASP1) modulation by intracellular Cl– concentration	4
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How maternal factors shape the immune system of breastfed infants to alleviate food allergy: A systematic and updated review	4
Characterization of age‐associated B cells in early drug‐naïve rheumatoid arthritis patients	4
Asymmetric T cell division of GAD65 specific naive T cells contribute to an early divergence in the differentiation fate into memory T cell subsets	4
Host stimulator of interferon genes is essential for the efficacy of anti‐programmed cell death protein 1 inhibitors in non‐small cell lung cancer	4
Epithelial cell‐derived CD83 restores immune tolerance in the airway mucosa by inducing regulatory T‐cell differentiation	4
Polymorphonuclear myeloid‐derived suppressor cells play a proinflammatory role via TNF‐α+ B cells through BAFF/BTK/NF‐κB signalling pathway in th	4
Prevalence of salivary anti‐SARS‐CoV‐2 IgG antibodies in vaccinated children	3
Applications of single‐cell omics for chimeric antigen receptor T cell therapy	3
Oligodeoxynucleotides containing CpG motifs (CpG‐ODN) restores immune regulatory functions of airway macrophages of patients with asthma	3
Screening and anti‐glioma activity of Chiloscyllium plagiosum anti‐human IL‐13Rα2 single‐domain antibody	3
CD5L is upregulated upon infection with Mycobacterium tuberculosis with no effect on disease progression	3
Dysfunctional phenotype of systemic and pulmonary regulatory T cells associate with lethal COVID‐19 cases	3
The immunopeptidomes of two transmissible cancers and their host have a common, dominant peptide motif	3
Pellino3 ligase negatively regulates influenza B dependent RIG‐I signalling through downregulation of TRAF3‐mediated induction of the transcription factor IRF3 and	3
Editorial: Diverse responses to SARS‐CoV‐2 in the human population	3
SOX17 orchestrates immune evasion in early colorectal adenomas and cancers	3
NME4 suppresses NFκB2‐CCL5 axis, restricting CD8+ T cell tumour infiltration in oesophageal squamous cell carcinoma	3
Interleukin‐7 improves the fitness of regulatory T cells for adoptive transfer	3
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Malignancy‐associated immune responses: Lessons from human inborn errors of immunity	3
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A detective story of intermittent fasting effect on immunity	3