Immunology

Article	Citations
Issue Information	140
The hippo kinase MST1 negatively regulates the differentiation of follicular helper T cells	131
Hypoxic tumour‐derived exosomal miR‐1290 exacerbates the suppression of CD8+ T cells by promoting M2 macrophage polarization	119
Smart Biomaterials as Immunomodulators in Cancer Therapy	107
High common‐γ cytokine receptor levels promote expression of Interleukin‐2/Interleukin‐7 receptor α‐chains with implications on T‐cell differentiation and function	97
Unravelling the Immunological Enigma of Sickle Cell Disease: Current Understanding and Future Directions	88
Conditional knockout of oestrogen receptor alpha in CD11c+ cells impacts female survival and inflammatory cytokine profile in murine lupus	80
New Engineered‐Chimeric Botulinum Neurotoxin Mutant Acts as an Effective Bivalent Vaccine Against Botulinum Neurotoxin Serotype A and E	78
Maternal Carriage of Prevotella copri Is Associated With Increased Thymus Derived Naïve Regulatory T Cells in Cord Blood	55
Genetic Determinants of Peanut‐Specific IgG4 Levels in the Context of Sustained Oral Peanut Exposure in the LEAP	53
Mitochondrial DNA : A Key Alarmin Igniting the Inflammasome Fire in Health and Disease	51
A new strategy for immunotherapy of microsatellite‐stable (MSS)‐type advanced colorectal cancer: Multi‐pathway combination therapy with PD‐1/PD‐L1 inhibitors	50
Update on the current knowledge of lymphatic drainage system and its emerging roles in glioma management	48
The immune response to COVID‐19: Does sex matter?	45
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What's in a name? Nomenclature in immunology	39
Identification of different functions of CD8+ T cell subpopulations by a novel monoclonal antibody	38
Idiotopes of antibodies against HIV‐1 CD4‐induced epitope shared with those against microorganisms	37
Prognostic biomarkers associated with immune checkpoint inhibitors in hepatocellular carcinoma	37
DNA methylation trajectories during innate and adaptive immune responses of human B lymphocytes	36
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Immunogenicity and safety of SpikoGen®, an adjuvanted recombinant SARS‐CoV‐2 spike protein vaccine as a homologous and heterologous booster vaccination: A randomized placebo‐controlled trial	35
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Embedding of exogenous B cell epitopes on the surface of UreB structure generates a broadly reactive antibody response against Helicobacter pylori	34
β‐Glucan Protects Against Sepsis‐Induced Kupffer Cell Loss by Inhibiting Pyroptosis and Promoting Self‐Renewal	34
Large Extracellular Vesicles From Keratinocytes Expressing Human Papillomavirus Type 16 E6 / E7 Su	34
Dynamics of T follicular helper cells in patients with rheumatic diseases and subsequent antibody responses in a three‐dose immunization regimen of CoronaVac	31
Trispecific antibodies for cancer immunotherapy	31
Stem Cell‐Based Delivery of Immunomodulators for Overcoming Glioblastoma Immune Evasion	31
Identification of psoriasis‐associated immune marker G3BP2 through single‐cell RNA sequencing and meta analysis	30
STING Drives Psoriatic Inflammation by Promoting Neutrophil Recruitment and Facilitating NETosis	30
Challenge Specific Modulation of Responses to Adjuvant‐Induced Innate Immune Memory	30
Caspase‐6 is a key regulator of cross‐talk signal way in PANoptosis in cancer	29
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Assessment of IgG‐Fc glycosylation from individual RhD‐specific B cell clones reveals regulation at clonal rather than clonotypic level	28
KDM5A : A Master Epigenetic Regulator of Th2 Immunity and Allergic Disease Pathogenesis	28
Immunomodulatory Mechanisms of ILC2 in Lung Development: Emerging Insights Into Bronchopulmonary Dysplasia Pathogenesis	28
Inhibition of Pyruvate Dehydrogenase Kinase 2 Alleviates Concanavalin A‐Induced Acute Liver Injury by Regulating Myeloid‐Derived Suppressor Cells	27
5‐ FU Resistance Facilitates Immune Evasion in Esophageal Squamous Cell Carcinoma Through ADAM10 ‐	26
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Tertiary Lymphoid Structures Predict Prognosis and Immune Checkpoint Inhibitor Efficacy in Lung Squamous Cell Carcinoma	25
Early life vaccination reprograms the metabolism and function of myeloid cells in neonates	24
T cell maturation is significantly affected by SARS‐CoV‐2 infection	24
Antibodies to SARS‐CoV‐2 in patients with primary immunodeficiencies treated with nonspecific immunoglobulins	24
Induction of Regulatory T Cells After Virus Infection and Vaccination	24
CCR5‐Mediated Reprogramming of Regulatory T Cells and Monocytic‐Myeloid‐Derived Suppressor Cells in Young Dyslipidemic Individuals: A Plausible Therapeutic Approach	24
The alterations of innate immunity and enhanced severity of infections in diabetes mellitus	23
Expression of RAG and secondary gene rearrangement of BCR in mature peripheral B lymphocytes in Takayasu arteritis	23
A detective story of intermittent fasting effect on immunity	22
Microplastics in Allergic Rhinitis: Multimechanistic Drivers of Barrier Disruption and Immune Dysregulation	22
Targeting Neuropilin‐1 to Enhance Immunotherapy in Melanoma: Reducing Peripheral Treg‐Mediated Immunosuppression and Tumour Progression	22
Correlation between antibodies against the pathogenic pHERV‐W envelope protein and the inflammatory phase of multiple sclerosis	22
Resilient Biophysical Phenotype of Memory CD4 + T Cells in Long‐Lived Mice	21
Dietary human milk oligosaccharides reduce allergic airway inflammation by modulating SCFAs level and ILC2 activity	21
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Integration of Immune Responses and Transcriptomic Signatures Reveals the Efficacy of Maternal Genetic Vaccination in a Pregnant Model and Its Neonates	20
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Lineage Tracking Dissects the Fate of Neonatal iNKT Cells Later in Life	20
Activation‐induced marker assays for identification of Trypanosoma cruzi‐specific CD4 or CD8 T cells in chronic Chagas disease patients	19
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Helios—Illuminating the way for lymphocyte self‐control	19
6‐Mercaptopurine potently inhibits recruitment of SHP2 by phosphorylated PD‐1 to inhibit PD‐1 signalling and enhance T cell function	19
Dysregulated neutrophil extracellular traps formation in sepsis	19
Towards understanding the role of nanomedicine in targeting TNFR2 in rheumatoid arthritis	19
TLR9 activation is required for cytotoxic response elicited by baculovirus capsid display	18
A Novel Prophylaxis Strategy Using Ecotin as A Promising Adjuvant for Fc‐RBD Fusion Protein Vaccine of SARS	18
A Novel Polymersome Nanocarrier Promotes Anti‐Tumour Immunity by Improved Priming of CD8+ T Cells	18
Peripheral blood MR1 tetramer‐positive mucosal‐associated invariant T‐cell function is modulated by mammalian target of rapamycin complex 1 in patients with active tuberculosis	18
Diagnostic Significance of Metagenomic Next‐Generation Sequencing in Immunocompromised Patients With Suspected Pulmonary Infection	18
Dysregulation of B lymphocyte development in the SKG mouse model of rheumatoid arthritis	18
The Role of NLRP1 , AIM2 and MEFV Inflammasomes	18
Exercise Duration Modulates Cortisol Release and Chronic Cortisol Exposure Jeopardises T Cell Effector Functions	17
Mucosal‐associated invariant T cells in digestive tract: Local guardians or destroyers?	17

The soluble IL‐2 receptor α/CD25 as a modulator of IL‐2 function	17
CD226 deficiency exacerbated intestinal immune dysregulation in mice with dinitrochlorobenzene‐induced atopic dermatitis	17
Unravelling the Impact of Outer Membrane Protein, OmpA, From S. Typhimurium on Aberrant AID Expression and IgM to IgA Class Switching in H	16
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Antibody‐dependent cell‐mediated cytotoxicity using T cells with NK‐like phenotype in combination with avelumab, an anti‐PD‐L1 antibody	16
γδT Cells in IBD: Beneficial or Detrimental?	16
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Pneumolysin suppresses the initial macrophage pro‐inflammatory response to Streptococcus pneumoniae	16
Pla2g5 contributes to viral‐like‐induced lung inflammation through macrophage proliferation and LA/Ffar1 lung cell recruitment	16
Exploration of the efficacy of anti‐immunoglobulin E monoclonal antibodies in the treatment of allergic asthma	15
Ceftazidime reduces cellular Skp2 to promote type‐I interferon activity	15
GD2 ‐ CAR T Cell Therapy for H3K27M +	15
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Optimization of Immunotherapy Strategies Based on Spatiotemporal Heterogeneity of Tumour‐Associated Tissue‐Resident Memory T Cells	14
Helper innate lymphoid cells as cell therapy for cancer	14
Dual Functions of Treg in the Mucosal Barrier and Lung Cancer Microenvironment and Prospects for Targeted Therapy	14
Augmenting Macrophages Apoptosis Induced by Carnitine Palmitoyl Transferase 1A Inhibition via Acetyl‐CoA‐Associated Protein Acetylation	14
Eosinophil Biology Today—A Primer for Basic and Clinical Investigators	14
Paleo‐immunology of human anti‐carbohydrate antibodies preventing primate extinctions	14
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The Roles of T Cells in the Development of Metabolic Dysfunction‐Associated Steatohepatitis	14
An immunogenetic investigation of 30 autoimmune and autoinflammatory diseases and their links to psychiatric disorders in a nationwide sample	14
Sequential engagement of adhesion molecules and cytokine receptors impacts both piecemeal and anaphylactic degranulation of human basophils	13
Epstein–Barr Virus‐Induced 3 Attributes to TLR7‐Mediated Splenomegaly	13
Splenocytes with fucosylation deficiency promote T cell proliferation and differentiation through thrombospondin‐1 downregulation	13
CD5L attenuates allergic airway inflammation by expanding CD11chigh alveolar macrophages and inhibiting NLRP3 inflammasome activation via HDAC2	13
Autoantigen‐selected B cells are bystanders in spontaneous T cell‐driven experimental autoimmune hepatitis	13
Intramacrophage lipid accumulation compromises T cell responses and is associated with impaired drug therapy against visceral leishmaniasis	13
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IL‐10 indirectly modulates functional activity of CD4+CD28null T‐lymphocytes through LFA‐3 and HLA class II inhi	13
cAMP responsive element modulator α promotes effector T cells in systemic autoimmune diseases	13
Omicron breakthrough infections after triple‐dose inactivated COVID‐19 vaccination: A comprehensive analysis of antibody and T‐cell responses	13
Correction to “Pla2g5 Contributes to Viral‐Like‐Induced Lung Inflammation Through Macrophage Proliferation and LA /Ffar1 Lung Cell Recruitment”	12
PI3Kγ Pathway Contributes to Neuroinflammation and Neuronal Death Induced by Zika Virus Infection	12
TIM3/CEACAM1 pathway involves in myeloid‐derived suppressor cells induced CD8+ T cells exhaustion and bone marrow inflammatory microenvironment in myelodysp	12
Sphingosine‐1‐Phosphate Signalling Inhibition Suppresses Th1‐Like Treg Generation by Reversing Mitochondrial Uncoupling	12
Polygenic TB control and the sequence of innate/adaptive immune responses to infection: MHC‐II alleles determine the size of the S100A8/9‐producing neutroph	12
Tumour‐associated neutrophils: Potential therapeutic targets in pancreatic cancer immunotherapy	12
Cooperative induction of CXCL chemokines by inflammatory cytokines and oxidized phospholipids	12
Ectopic endometriotic stromal cells‐derived lactate induces M2 macrophage polarization via Mettl3/Trib1/ERK/STAT3 signalling pathway in endometriosis	12
The Neurobeachin‐like 2 protein (NBEAL2) controls the homeostatic level of the ribosomal protein RPS6 in mast cells	12
IL‐1β promotes IL‐17A production of ILC3s to aggravate neutrophilic airway inflammation in mice	12
IBD functions as a double‐edged sword for food allergy in BALB/c mice model	12
Simultaneous Blockade of CD209 and CD209L by Monoclonal Antibody Does Not Provide Sufficient Protection Against Multiple Viral Infections In Vivo	12
Gamma Delta T Cells in the Tumour Microenvironment: A Double‐Edged Sword	12
mTORC2 contributes to systemic autoimmunity	11
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K33 only mutant ubiquitin augments bone marrow‐derived dendritic cell‐mediated CTL priming via PI3K‐Akt pathway	11
Acute Plasmodium yoelii17XNL Infection During BCG Vaccination Limits T Cell Responses and Mycobacterial Growth Inhibition	11
Alternative pathway dysregulation in tissues drives sustained complement activation and predicts outcome across the disease course in COVID‐19	11
Mitochondrial Activity Regulates Human T Helper 17 Differentiation and Function	11
NRP1 downregulation correlates with enhanced ILC2 responses during IL‐33 challenge	11
Exhausted CD8 + T Cell in HIV Infection Exhibits an Impaired Bioene	11
Role of airway epithelium in viral respiratory infections: Can carbocysteine prevent or mitigate them?	11
Vaccines, adjuvants and key factors for mucosal immune response	11
CD73 Expression by CD4 + T Cells Marks Early Effector Memory T Cells	11
Epigenetics: An opportunity to shape innate and adaptive immune responses	11
Myeloid‐derived suppressor cells from tumour‐bearing mice induce the population expansion of CD19hiFcγRIIbhi regulatory B cells via PD‐L1	11
Staphylococcus aureus biofilm properties and chronic rhinosinusitis severity scores correlate positively with total CD4+ T‐cell frequencies and inversely with its Th1, Th1	11
Activation of the Lectin Pathway Drives Persistent Complement Dysregulation in Long COVID	11
Lung adenocarcinoma manifesting as subsolid nodule potentially represents tumour in the equilibrium phase of immunoediting	11
Signal Transducer and Activator of Transcription ( STAT ) Proteins Regulate Mucosal‐Associated Invariant T ( MAIT	10
Chimerism of avian IgY‐scFv and truncated IgG‐Fc: A novel strategy in cross‐species antibody generation and enhancement	10
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Microneedle‐Delivered Multivalent MPXV DNA Vaccines Induce Promising Immunity Profiles and Cross‐Protection in Mice	10
SIRT6 Ameliorates Atherosclerosis by Inhibiting M1 Macrophage Polarisation Through Deacetylated‐ <	10
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The Contribution of Complement System in Multiple Sclerosis: Mechanisms and Therapeutic Potentials	10
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SpaCBA ‐ OVA Liposome Reprograms Immune Tolerance to Ameliorate Allergic Rhinitis via DC	10
Strategies of AI ‐Driven CAR ‐T Cell Therapy Towards Solid Tumours	10
IL‐6 Signalling to Responding T Cells Is Key to Calcitonin Gene‐Related Peptide‐Exposed Endothelial Cell Enhancement of Th17 Immunity During Langerhans Cell Antigen Presentation	10
Correction to “Psychological stress to ovalbumin peptide‐specific T‐cell receptor transgenic mice impairs the suppressive ability of type 1 regulatory T cell”	9
Mycobacterium potentiates protection from colorectal cancer by gut microbial alterations	9
The role of HMGB1 in COVID‐19‐induced cytokine storm and its potential therapeutic targets: A review	9
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Induction of a cytokine storm involves suppression of the Osteopontin‐dependent TH1 response	9
Leveraging Mycobacterium tuberculosis Rv1507A Protein for Improved Immunogen	9

Distinct contributions of the innate immune receptors TLR2 and RP105 to formation and architecture of structured lung granulomas in mice infected with Mycobacterium tuberculos	9
The Immune System and Cellular Senescence: A Complex Interplay in Aging and Disease	9
Mast cells contribute to T‐cell accumulation in the bronchoalveolar space in mice with IL‐33‐induced airway inflammation	9
βhCG mediates immune suppression through upregulation of CD11b+Gr1+ myeloid derived suppressor cells, CD206+M2 macrophages,	9
Erratum to “New Role of Gramicidin A in RIG ‐I‐Like Receptors‐Mediated IFN Signalling”	9
TREM1/DAP12 based novel multiple chain CAR‐T cells targeting DLL3 show robust anti‐tumour efficacy for small cell lung cancer	9
Role of CD14 in human disease	9
Circadian rhythm regulation in the immune system	9
Deciphering the IgG Idiotype Network Through Proteomic Analysis of Potential Targets in SARS‐CoV‐2‐Induced Immune Responses	9
Bidirectional Regulation in the Tumour Microenvironment: The Interaction Between Tumour‐Associated Macrophages and T Cells Reshapes the Paradigm of Cancer Immunotherapy	8
Pellino3 ligase negatively regulates influenza B dependent RIG‐I signalling through downregulation of TRAF3‐mediated induction of the transcription factor IRF3 and	8
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The functional diversity of tissue‐resident natural killer cells against infection	8
Identification of neoantigens in oesophageal adenocarcinoma	8
Fc Fragment of IgE Receptor Ig (FCER1G) acts as a key gene involved in cancer immune infiltration and tumour microenvironment	8
PD‐1 expression on tumour‐infiltrating cells is a prognostic factor for relapsed or refractory diffuse large B‐cell lymphoma	8
Clinical C3 Inhibition With AMY‐101 Reveals Novel Insights Into IL‐8‐Driven Inflammation in COVID‐19	8
CD39 pathway inhibits Th1 cell function in tuberculosis	8
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NR4A1 mediates NK‐cell dysfunction in hepatocellular carcinoma via the IFN‐γ/p‐STAT1/IRF1 pathway	8
Coexistence of IL12Rβ1 and BTK Mutations in a Family	8
SNX17 Regulates Antigen Internalisation and Phagosomal Maturation by Dendritic Cells	8
Increased CD8dim and Decreased CD8bright T Cells as Immunological Signature for Multibacilary Leprosy Patients	8
Use of a Foamy‐Virus Vector System to Produce an ‘Off‐the‐Shelf’ Fcγ‐ CR ‐T Cell Product for the Treatment of Haematological and Solid Tumour Maligna	8
Peritoneal GATA6+ macrophage drives hepatic immunopathogenesis and maintains the Treg cell niche in the liver	8
A Review on Biosensors for Quantification of MCP‐1 as a Potential Biomarker in Diseases	7
Immunoparalysis in critically ill children	7
BXSB . Yaa : A Translational Model of Toll‐Like Receptor 7‐Type I Interferon‐Driven Systemic Lupus Erythematosus	7
Molecular Mediators of Metabolic Reprogramming in Cancer: Mechanisms, Regulatory Networks, and Therapeutic Strategies	7
Interferon‐β Triggers Z‐ DNA Binding Protein 1‐Mediated PANoptosis in T Cells of Anti‐Melanoma Dif	7
How maternal factors shape the immune system of breastfed infants to alleviate food allergy: A systematic and updated review	7
NKG2A‐checkpoint inhibition and its blockade critically depends on peptides presented by its ligand HLA‐E	7
Expression of GPR56 reflects a hypoactivated state of circulating B cells and is downregulated in B cell subsets in patients with early‐stage lung adenocarcinoma	7
New sights of low dose IL‐2: Restoration of immune homeostasis for viral infection	7
CD5L is upregulated upon infection with Mycobacterium tuberculosis with no effect on disease progression	7
Engineered polyspecific antibodies: A new frontier in the field of immunotherapeutics	7
A robust platform for integrative spatial multi‐omics analysis to map immune responses to SARS‐CoV ‐2 infection in lung tissues	7
Break down the barriers of auto‐inflammation: How to deal with a monogenic auto‐inflammatory disease and immuno‐haematological features in 2022?	7
Barriers and Strategies to Enhance CAR ‐T Cell Infiltration in Solid Tumours: A Systematic Review	7
Impact of Pre‐Infection COVID‐19 Vaccination on the Incidence and Severity of Long COVID: A Retrospective Case–Control Study	7
Downregulation of type I interferon signalling pathway by urate in primary human PBMCs	7
Regulatory B cells protect against chronic hypoxia‐induced pulmonary hypertension by modulating the Tfh/Tfr immune balance	7
Complement: Functions, location and implications	7
Impact of sex differences on the clinical presentation, pathogenesis, treatment and prognosis of Sjögren's syndrome	7
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Targeting Immune Cell Metabolism: A Promising Therapeutic Approach for Cardiovascular Disease	6
Effect of gut flora mediated‐bile acid metabolism on intestinal immune microenvironment	6
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Keap1 moderates the transcription of virus induced genes through G9a‐GLP and NFκB p50 recruitment	6
Dopaminergic inhibition of human neutrophils is exerted through D1‐like receptors and affected by bacterial infection	6
The turning point of COVID‐19 severity is associated with a unique circulating neutrophil gene signature	6
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Computer Integrated Dominant Epitopes Evoke Protective Immune Response Against Streptococcus pneumoniae	6
Elucidation of the signalling pathways for enhanced exosome release from Mycobacterium‐infected macrophages and subsequent induction of differentiation	6
TRAF5 regulates intestinal mucosal Th1/Th17 cell immune responses via Runx1 in colitis mice	6
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27‐Hydroxycholesterol Exacerbates the Pathogenesis of Asthma	6
Mycobacterium avium Subsp. paratuberculosis and Human Endogenous Retrovirus in Italian Patients With Inflammatory Bowel Disease (IBD) and Irritable Bowel	6
Inhibition of leukotriene‐B4 signalling‐mediated host response to tuberculosis is a potential mode of adjunctive host‐directed therapy	6
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PCK2 maintains intestinal homeostasis and prevents colitis by protecting antibody‐secreting cells from oxidative stress	6
USP12 positively regulates M‐MDSC function to inhibit antitumour immunity through deubiquitinating and stabilizing p65	6
Role of novel protein acylation modifications in immunity and its related diseases	6
The dual role of regulatory T cells in hepatitis B virus infection and related hepatocellular carcinoma	6
Abrogation and homeostatic restoration of IgE responses by a universal IgE allergy	6
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Eleven‐month longitudinal study of antibodies in SARS‐CoV‐2 exposed and naïve primary health care workers upon COVID‐19 vaccination	6
The Role of Innate Immunity in Healthy Aging Through Antimicrobial Peptides	6
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Antibiotic‐Induced Dysbiosis of the Gut Microbiota Shifts Host Tryptophan Metabolism and Increases the Susceptibility of Mice to Pulmonary Infection With Pseudomonas aeruginosa	6
CD57 T cells associated with immunosenescence in adults living with HIV or AIDS	6
Icariin Induces Chondrocyte Degeneration via Activation of the NF‐κB Signalling Pathway and Reduces the Inflammation Factor Expression Induced by Lipopolysaccharide	6
Blood Immunopathology of Tuberculosis Patients Disrupts Monocyte‐Dependent T‐Cell Activation and Cytokine Expression	6
SAA1 as a Potential Early Diagnostic Biomarker for Sepsis Through Integrated Proteomics and Metabolomics	6
Application and Perspectives of Immunotherapy in Head and Neck Squamous Cell Carcinoma	6
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Antibody Polyreactivity: A Challenger of Immune Paradigms	6
Involvement of Janus kinase‐dependent Bcl‐xL overexpression in steroid resistance of group 2 innate lymphoid cells in asthma	6
Unlocking the role of the B7‐H4 polymorphism in psoriasis: Insights into methotrexate treatment outcomes: A prospective cohort study	6
RNA technology and nanocarriers empowering in vivo chimeric antigen receptor therapy	6
Epidemiology and Genetics of Rheumatic Diseases Suggest a Constant Rate of DNA Damage as Underlying Cause	5
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Pathogenetic role and clinical significance of interleukin‐1β in cancer	5
IL‐2 amplifies quantitative TCR signalling inputs to drive Th1 and Th2 differentiation	5
Circular RNA ACTR2 activates M2 polarization of macrophages through activating Yes‐associated protein signalling and contributes to renal fibrosis	5
Monocyte pathology in human tuberculosis is due to plasma milieu changes and aberrant STAT signalling	5
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Lactate and Lactylation in Immune Cell Function and Autoimmune Diseases: Mechanisms and Therapeutic Potential	5
PKCζ activation promotes maturation of cord blood T cells towards a Th1 IFN‐γ propensity	5
Roles of S100A8, S100A9 and S100A12 in infection, inflammation and immunity	5
Upregulated TCF1+ Treg Cells With Stronger Function in Systemic Lupus Erythematosus Through Activation of the Wnt‐β‐Catenin	5
Dual blockages of a broad and potent neutralizing IgM antibody targeting GH loop of EV‐As	5
Advancements in Nipah virus treatment: Analysis of current progress in vaccines, antivirals, and therapeutics	5
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B Cells as a Host of Persistent Salmonella Typhimurium	5