Gut

Papers
(The TQCC of Gut is 18. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
Defining the key intrahepatic gene networks in HCV infection driven by sex1549
Picking up microbial clues in early-onset colorectal cancer1221
Finding a mate for MLCK: improving the potential for therapeutic targeting of gut permeability852
Immunomodulation and entry inhibition: selgantolimod’s double punch against hepatitis B virus443
Unusual history of ‘stitch’295
Response to McAlindon’s letter259
Unusual case of severe diarrhoea211
Correction:P97 A patient information bundle outlining dietary advice in liver disease specific to the cost of living crisis improves patient care: ‘Looking after Your Liver for Less’202
Perturbation of mRNA splicing in liver cancer: insights, opportunities and challenges201
Rate of suitable cases for primary EUS-guided biliary drainage in distal malignant biliary obstruction201
Mass cytometry-based peripheral blood analysis as a novel tool for early detection of solid tumours: a multicentre study199
IL-3 receptor signalling suppresses chronic intestinal inflammation by controlling mechanobiology and tissue egress of regulatory T cells187
HBcrAg values may predict virological and immunological responses to pegIFN-a in NUC-suppressed HBeAg-negative chronic hepatitis B185
Impact of margin thermal ablation after endoscopic mucosal resection of large (≥20 mm) non-pedunculated colonic polyps on long-term recurrence183
COVID-19 and liver disease179
Where are we with gastric cancer screening in Europe in 2024?168
Holistic healthcare in inflammatory bowel disease: time for patient-centric approaches?162
Third Asia-Pacific consensus recommendations on colorectal cancer screening and postpolypectomy surveillance158
Liquid biopsy to identify Barrett’s oesophagus, dysplasia and oesophageal adenocarcinoma: theEMERALDmulticentre study156
Innumerable nodules in all parts of the small intestine155
Genetically proxied ketohexokinase function and risk of colorectal cancer: a Mendelian randomisation study153
Crohn’s disease and ulcerative colitis exhibit prediagnostic antibody signatures with shared and divergent changes towards disease onset151
Growth rates and histopathological outcomes of small (6–9 mm) colorectal polyps based on CT colonography surveillance and endoscopic removal148
Current therapies and new developments in NASH143
Absence of a pancreatic microbiome in intraductal papillary mucinous neoplasm143
Autologous regulatory T-cell transfer in refractory ulcerative colitis with concomitant primary sclerosing cholangitis142
Gut virome-colonisingOrthohepadnavirusgenus is associated with ulcerative colitis pathogenesis and induces intestinal inflammationin vivo142
A mucus production programme promotes classical pancreatic ductal adenocarcinoma141
Establishment of enterically transmitted hepatitis virus animal models using lipid nanoparticle-based full-length viral genome RNA delivery system140
S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos138
Prospective, double-blind diagnostic multicentre study of confocal laser endomicroscopy for wheat sensitivity in patients with irritable bowel syndrome137
Methionine deficiency facilitates antitumour immunity by altering m6A methylation of immune checkpoint transcripts135
Perplexing case of abdominal pain with eosinophilia and fasciitis134
Impact of climate change on vulnerable populations131
Need for standardised approaches to human microbiome research using the example of colorectal neoplasia research127
Interactive enhancer hubs (iHUBs) mediate transcriptional reprogramming and adaptive resistance in pancreatic cancer125
Correction: Inflammatory cell-derived CXCL3 promotes pancreatic cancer metastasis through a novel myofibroblast-hijacked cancer escape mechanism124
GI highlights from the literature121
Intron-mediated enhancement of SPINK1 expression for pancreatitis therapy121
Reply to: Non-invasive tests and advanced chronic liver disease in NAFLD: two steps forward and one step back?117
Tiny contributors to severe obesity inside the gut117
Shaggy white lesion with morphological changes in the oesophagus115
From clinical trials to clinical practice: how should we design and evaluate prediction models in the care of IBD?110
Humoral response to SARS-CoV-2 infection among liver transplant recipients109
Host transcriptome signatures in human faecal-washes predict histological remission in patients with IBD108
Most excess years of potential life loss among individuals with cirrhosis during the pandemic were not related to COVID-19107
Lumen-apposing metal stents versus double-pigtail plastic stents for infected necrotising pancreatitis: more doubts than answers101
Discovery of the pancreatic basal cell: a new candidate for an adult stem cell emerges100
Rare cause of obstructive jaundice97
Endoscopic mucosal and submucosal cutting for long benign oesophageal strictures97
Integrated multimodel analysis of intestinal inflammation exposes key molecular features of preclinical and clinical IBD96
Gastrointestinal microbiota and inflammasomes interplay in health and disease: a gut feeling95
Selective decontamination of the digestive tract in critically ill children: fighting fire with fire or burning down the house?95
Association between appendectomy and Parkinson’s disease from the UK Biobank94
Definite benefits of GLP-1 receptor agonists: what is the risk of gastroparesis and lung aspiration?93
Unveiling 8 years of duodenoscope contamination: insights from a retrospective analysis in a large tertiary care hospital93
Time for arginine methylation: PRMT5 inhibition to advance cholangiocarcinoma treatment93
Faecal occult blood loss accurately predicts future detection of colorectal cancer. A prognostic model90
Reflux conditions induce E-cadherin cleavage and EMT via APE1 redox function in oesophageal adenocarcinoma90
Engineered anti-PDL1 with IFNα targets both immunoinhibitory and activating signals in the liver to break HBV immune tolerance89
24-Nor-ursodeoxycholic acid improves intestinal inflammation by targeting TH17 pathogenicity and transdifferentiation89
MicroRNA-223 attenuates hepatocarcinogenesis by blocking hypoxia-driven angiogenesis and immunosuppression88
Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression87
New entity of adult ultra-short coeliac disease: the first international cohort and case–control study86
British Society of Gastroenterology guidelines on sedation in gastrointestinal endoscopy86
Tumour-intrinsic alterations and stromal matrix remodelling promote Wnt-niche independence during diffuse-type gastric cancer progression84
Endoscopic stratification of gastric intestinal metaplasia: where are we, where do we want to go and how do we get there?84
SARS-CoV-2 vaccination in patients with GI and hepatobiliary carcinoma: a call for booster vaccination83
Treatment of type 2 diabetes with MASLD: new evidence for personalised medicine81
Environmental and healthcare trade-offs between single-use and reusable gastroscopes81
Rethinking routine mapping biopsies in gastric intestinal metaplasia: justification for endoscopic stratification77
Ebastine for the treatment of irritable bowel syndrome: old drug, new tricks?76
GI highlights from the literature76
Withdrawal of the British Society of Gastroenterology IBD risk grid for COVID-19 severity76
Comparison between non-pulmonary and pulmonary immune responses in a HIV decedent who succumbed to COVID-1974
APCmosaicism, not always isolated: two first-degree relatives with apparently distinctAPCmosaicism74
Correction: Prevalence of irritable bowel syndrome and functional dyspepsia after acute gastroenteritis: systematic review and meta-analysis74
Association between inflammatory bowel disease and Alzheimer’s disease: multivariable and bidirectional Mendelian randomisation analyses72
Impact of age, comorbidities and relevant changes on surveillance strategy of intraductal papillary mucinous neoplasms: a competing risk analysis72
Postprandial symptoms in disorders of gut-brain interaction and their potential as a treatment target71
Immunopathogenesis and environmental triggers in coeliac disease70
Endoscopic papillectomy versus surgical ampullectomy for adenomas and early cancers of the papilla: a retrospective Pancreas2000/European Pancreatic Club analysis69
British Society of Gastroenterology interim framework for addressing the COVID-19-related backlog in inflammatory bowel disease colorectal cancer surveillance69
Anticoagulation in colorectal ESD: implications for bleeding risk management69
Dietary fibres and IBS: translating functional characteristics to clinical value in the era of personalised medicine68
Enolase represents a metabolic checkpoint controlling the differential exhaustion programmes of hepatitis virus-specific CD8+T cells68
Targeting hepatic stellate cells to combat liver fibrosis: where do we stand?68
Hypophosphataemia following ferric derisomaltose and ferric carboxymaltose in patients with iron deficiency anaemia due to inflammatory bowel disease (PHOSPHARE-IBD): a randomised clinical trial68
Targeting MS4A4A on tumour-associated macrophages restores CD8+ T-cell-mediated antitumour immunity67
FSTL1 promotes liver fibrosis by reprogramming macrophage function through modulating the intracellular function of PKM265
Fasting-mimicking diet-enrichedBifidobacterium pseudolongumsuppresses colorectal cancer by inducing memory CD8+T cells64
GI highlights from the literature63
Molecular portraits of patients with intrahepatic cholangiocarcinoma who diverge as rapid progressors or long survivors on chemotherapy62
GI highlights from the literature62
Fatal intestinal disease: a case of recurrent lower gastrointestinal bleeding61
It takes two to TAM-go61
Non-invasive assessment of MASH resolution60
Nuclear Pirin promotes HCC by acting as a key inflammation-facilitating factor60
A black liver59
NLRP6 deficiency enhances macrophage-mediated phagocytosis via E-Syt1 to inhibit hepatocellular carcinoma progression59
Gastric emptying study before gastric peroral endoscopic myotomy (G-POEM): can intragastric meal distribution be a predictor of success?59
Submucosal steroid pre-injection strategy to prevent oesophageal stricture after circumferential endoscopic submucosal dissection59
Monocyte phenotypic liquid biopsy for NASH and liver fibrosis diagnosis: a new kid on the block58
Abnormal gastrointestinal motility is a major factor in explaining symptoms and a potential therapeutic target in patients with disorders of gut–brain interaction58
Clinical relevance of biomarkers in cholangiocarcinoma: critical revision and future directions58
Spatial dissection of tumour microenvironments in gastric cancers reveals the immunosuppressive crosstalk betweenCCL2+fibroblasts andSTAT3-activated macrophages57
Comparison of drugs for active eosinophilic oesophagitis: systematic review and network meta-analysis56
Response letter to the editor55
NFATc1 signaling drives chronic ER stress responses to promote NAFLD progression55
Quest for HBV functional cure: what have we learnt from silencing RNAs?55
Unravelling the obesity paradox in MASLD patients with extrahepatic cancer54
Porcine-derived pancreatic enzyme replacement therapy may be linked to chronic hepatitis E virus infection in cystic fibrosis lung transplant recipients54
Understanding the malignant potential of gastric metaplasia of the oesophagus and its relevance to Barrett’s oesophagus surveillance: individual-level data analysis54
Gut check: can other microbes or communities phenocopyH. pylori’s early gastric pathology?54
MED12 loss activates endogenous retroelements to sensitise immunotherapy in pancreatic cancer53
Response by Abrahami et al to letter regarding article ‘Proton pump inhibitors and risk of colorectal cancer’53
National Institute for Health and Care Excellence (NICE) guidance on monitoring and management of Barrett’s oesophagus and stage I oesophageal adenocarcinoma53
GI highlights from the literature52
Correction:PMO-29 Switching between infliximab biosimilars: experience from two inflammatory bowel disease centres51
Diagnostic dilemma: a patient with diarrhoea51
Risk of metachronous advanced neoplasia in patients with serrated lesions depending on follow-up schedule50
Pericyte drives the formation of circulating tumour cell-neutrophil clusters to promote colorectal cancer metastasis50
Human milk oligosaccharide 2�-fucosyllactose protects against high-fat diet-induced obesity by changing intestinal mucus production, composition and degradation linked to changes in gut microbiota and49
Human enteric nervous system progenitor transplantation improves functional responses in Hirschsprung disease patient-derived tissue49
Targeting ER protein TXNDC5 in hepatic stellate cell mitigates liver fibrosis by repressing non-canonical TGFβ signalling49
Uniting the global gastroenterology community to meet the challenge of climate change and non-recyclable waste49
Interplay between diet, circulating indolepropionate concentrations and cardiometabolic health in US populations49
Targeting MYC effector functions in pancreatic cancer by inhibiting the ATPase RUVBL1/249
Cultivated human intestinal fungusCandida metapsilosisM2006B attenuates colitis by secreting acyclic sesquiterpenoids as FXR agonists49
NNMT enriches for AQP5+cancer stem cells to drive malignant progression in early gastric cardia adenocarcinoma48
APCandP53mutations synergise to create a therapeutic vulnerability to NOTUM inhibition in advanced colorectal cancer48
Lysosomal lipid switch sensitises to nutrient deprivation and mTOR targeting in pancreatic cancer48
Evaluation of proton pump inhibitors and risks of gastric cancer47
Combining epigenetic modulation: the next step for HCC immunotherapy?47
Prevalence of irritable bowel syndrome and functional dyspepsia after acute gastroenteritis: systematic review and meta-analysis47
Correction: Fatty acids promote fatty liver disease via the dysregulation of 3-mercaptopyruvate sulfurtransferase/hydrogen sulfide pathway47
Long-term hepatitis B surface antigen response after finite treatment of ARC-520 or JNJ-398946
Targeting TL1A and DR3: the new frontier of anti-cytokine therapy in IBD46
IL-20 subfamily cytokines impair the oesophageal epithelial barrier by diminishing filaggrin in eosinophilic oesophagitis45
Synergistic association of sodium-glucose cotransporter-2 inhibitor and metformin on liver and non-liver complications in patients with type 2 diabetes mellitus and metabolic dysfunction-associated st45
Autologous T cell responses to primary human colorectal cancer spheroids are enhanced by ectonucleotidase inhibition44
Long-term use of proton pump inhibitors (PPIs) is associated with an increased risk of type 2 diabetes44
Combining dietary fibres to reduce intestinal gas production in patients with IBS44
Single-cell sequencing unveils distinct immune microenvironments with CCR6-CCL20 crosstalk in human chronic pancreatitis43
Gut microbiota as non-invasive diagnostic and prognostic biomarkers for natural killer/T-cell lymphoma43
Landscape of the gut mycobiome dynamics during pregnancy and its relationship with host metabolism and pregnancy health43
The Peptidoglycan Recognition Protein 1 confers immune evasive properties on pancreatic cancer stem cells43
Assessment of the yearly carbon emission of a gastrointestinal endoscopy unit42
Global prevalence of non-alcoholic fatty liver disease in type 2 diabetes mellitus: an updated systematic review and meta-analysis42
Hepatic TM6SF2 activates antitumour immunity to suppress metabolic dysfunction-associated steatotic liver disease-related hepatocellular carcinoma and boosts immunotherapy42
Fungi and cancer42
Dominant-negative effect of lactase missense variants: hetero-complex assembly with the wild-type enzyme impairs intracellular trafficking and digestive function42
Withdrawal of antitumour necrosis factor in patients with inflammatory bowel disease in remission: a randomised placebo-controlled clinical trial of GETECCU42
The road to a world-unified approach to the management of patients with gastric intestinal metaplasia: a review of current guidelines41
Correction:Sympathetic nervous activation, mitochondrial dysfunction and outcome in acutely decompensated cirrhosis: the metabolomic prognostic models (CLIF-C MET)40
Correction:O4 Acceptability and feasibility of a multimodal early detection pilot study for liver disease in high risk groups: “Alright My Liver?”40
Is HBx protein the X factor in the pathogenesis of IBD?39
Specific gut pathobionts escape antibody coating and are enriched during flares in patients with severe Crohn’s disease39
Eosinophils: a novel therapeutic target to promote liver regeneration in acute liver injury?39
GI highlights from the literature38
Is the significant risk of perioperative complications associated with radical surgery following non-curative endoscopic submucosal dissection for early colorectal cancer still acceptable?38
Tailoring treatment to the circumstance: reasoning behind metal versus plastic drainage of pancreatic collections38
Trends and cross-country inequality in the incidence of GI cancers among the working-age population from 1990 to 2021: a Global Burden of Disease 2021 analysis37
GI snapshot: arrhythmia, dysphagia and weight loss in a 71-year-old man37
Cellular immunotherapies and immune cell depleting therapies in inflammatory bowel diseases: the next magic bullet?36
SARS-CoV-2 Omicron variant infection was associated with higher morbidity in patients with cirrhosis36
HBV integrations reshaping genomic structures promote hepatocellular carcinoma35
Antibody response to the BNT162b2 SARS-CoV-2 vaccine in paediatric patients with inflammatory bowel disease treated with anti-TNF therapy35
Correction: Macrophages direct cancer cells through a LOXL2-mediated metastatic cascade in pancreatic ductal adenocarcinoma35
Gut microbiome and dietary fibre intake strongly associate with IgG function and maturation following SARS-CoV-2 mRNA vaccination35
Maternal antibiotic exposure during pregnancy and risk of IBD in offspring: a population-based cohort study35
Alternative splicing of viral transcripts: the dark side of HBV35
Establishment of a validated central reading system for ileocolonoscopy in an academic setting35
Variceal band ligation and carvedilol: together forever, or not?35
DYRK1B blockade promotes tumoricidal macrophage activity in pancreatic cancer34
Precancerous nature of intestinal metaplasia with increased chance of conversion and accelerated DNA methylation34
Sex-based differences in prescribed medications, surgical procedures and disease-related complications in IBD34
Recent advances in incretin-based therapy for MASLD: from single to dual or triple incretin receptor agonists33
British Society of Gastroenterology guidelines for the diagnosis and management of cholangiocarcinoma33
Liver stiffness thresholds to predict disease progression and clinical outcomes in bridging fibrosis and cirrhosis33
Nuclear translocation of plasma membrane protein ADCY7 potentiates T cell-mediated antitumour immunity in HCC33
Maternal obesity, pregnancy weight gain, and birth weight and risk of colorectal cancer33
Vessel and tissue recognition during third-space endoscopy using a deep learning algorithm32
Multiomics reveal unique signatures of human epiploic adipose tissue related to systemic insulin resistance32
Estimating the environmental impact of disposable endoscopic equipment and endoscopes32
Simplified Helicobacter pylori therapy for patients with penicillin allergy: a randomised controlled trial of vonoprazan-tetracycline dual therapy32
CAF-macrophage crosstalk in tumour microenvironments governs the response to immune checkpoint blockade in gastric cancer peritoneal metastases32
Combining ferroptosis induction with MDSC blockade renders primary tumours and metastases in liver sensitive to immune checkpoint blockade31
Cold versus hot snare endoscopic mucosal resection for large (≥15 mm) flat non-pedunculated colorectal polyps: a randomised controlled trial31
Basal levels of microbiota-driven subclinical inflammation are associated with anastomotic leak in patients with colorectal cancer31
Endocytoscopy with automated multispectral intestinal barrier pathology imaging for assessment of deep healing to predict outcomes in ulcerative colitis31
Integrated analysis of the faecal metagenome and serum metabolome reveals the role of gut microbiome-associated metabolites in the detection of colorectal cancer and adenoma30
Single-cell omics in inflammatory bowel disease: recent insights and future clinical applications30
Organoids in gastrointestinal diseases: from experimental models to clinical translation30
Effectiveness of mailed outreach and patient navigation to promote HCC screening process completion: a multicentre pragmatic randomised clinical trial30
More than meets the eye: a strange cause of bowel obstruction and perforation30
Stool microRNA profiling— dumpster diving for a master marker?30
Phenotypic CD8 T cell profiling in chronic hepatitis B to predict HBV-specific CD8 T cell susceptibility to functional restoration in vitro30
Artificial intelligence applied to ‘omics data in liver disease: towards a personalised approach for diagnosis, prognosis and treatment30
Alcohol exhibits contrasting effects on CD8+ T cells in the gut and liver in alcohol-associated liver disease30
Alterations to the duodenal microbiota are linked to gastric emptying and symptoms in functional dyspepsia30
What to do about the leaky gut30
Porcine-derived pancreatic enzyme replacement therapy: a cause of hepatitis E virus transmission?29
Reply to Newmanet al‘Response to epidemiology of inflammatory bowel disease in men with high-risk homosexual activity’29
Ferritin—a promising biomarker in MASLD29
Unusual cause of abdominal pain29
An unusual cause of oesophageal stricture29
Genetic and transcriptomic landscape of colonic diverticulosis28
Correction:Residual SARS-CoV-2 viral antigens detected in GI and hepatic tissues from five recovered patients with COVID-1928
Toxic microbiome and progression of chronic kidney disease: insights from a longitudinal CKD-microbiome study28
eCura and W-eCura: different scores, different populations, same goal28
Correction:O11 Utilising peer support workers in hepatitis C screening in emergency departments: a pilot study28
Key metabolomic alterations are associated with ulcerative colitis disease state and activity: a validation analysis27
Patient-reported experience of colonoscopy in Italy: a multicentre prospective observational study27
Intravital imaging: dynamic insights into liver immunity in health and disease27
MAFLD, HCC and the dilemma of (changing) terminology in liver diseases27
Presenilins: the hidden guardians of gut health in Alzheimers disease27
Adherent-invasive Escherichia coli in Crohn’s disease: the 25th anniversary27
Is the biogeography of the mucosa-associated microbiota a key factor affecting primary sclerosing cholangitis disease course and treatment?27
GM-CSF drives myelopoiesis, recruitment and polarisation of tumour-associated macrophages in cholangiocarcinoma and systemic blockade facilitates antitumour immunity27
Gnotobiotic mice housing conditions critically influence the phenotype associated with transfer of faecal microbiota in a context of obesity26
Purified oat protein can trigger acute symptoms linked to immune activation in coeliac disease patients but not histological deterioration26
Clinical outcome of non-curative endoscopic submucosal dissection for early colorectal cancer26
Inhibition of YTHDF1 by salvianolic acid overcomes gluten-induced intestinal inflammation26
Over-the-scope-clips versus standard treatment in high-risk patients with acute non-variceal upper gastrointestinal bleeding: a randomised controlled trial (STING-2)26
Accuracy of measuring colorectal polyp size in pathology: a prospective study26
Post-acute COVID-19 syndrome and gut dysbiosis linger beyond 1 year after SARS-CoV-2 clearance26
CRIP1 fosters MDSC trafficking and resets tumour microenvironment via facilitating NF-κB/p65 nuclear translocation in pancreatic ductal adenocarcinoma25
Performance of the China-CLIF framework in acute-on-chronic liver failure: a multicohort study across all aetiologies25
Suppressor CD4+T cells expressing HLA-G are expanded in the peripheral blood from patients with acute decompensation of cirrhosis25
Efficacy of biological therapies and small molecules in moderate to severe ulcerative colitis: systematic review and network meta-analysis25
DNA-methylation signature accurately differentiates pancreatic cancer from chronic pancreatitis in tissue and plasma25
Long-term liver-related outcomes and liver stiffness progression of statin usage in steatotic liver disease25
Patient selection for urgent endoscopic retrograde cholangio-pancreatography by endoscopic ultrasound in predicted severe acute biliary pancreatitis (APEC-2): a multicentre prospective study25
Omega-3 polyunsaturated fatty acids: moving towards precision use for prevention and treatment of colorectal cancer25
Faecal immunochemical testing (FIT) in patients with signs or symptoms of suspected colorectal cancer (CRC): a joint guideline from the Association of Coloproctology of Great Britain and Ireland (ACPG25
Germline mutations and pancreatic cancer risk in chronic pancreatitis25
Cold versus hot EMR for large duodenal adenomas25
Reconsidering statins in MASLD: beyond cardiovascular protection to multisystem benefit25
Stressed hepatocyte sustains alcohol-associated hepatitis progression by producing leukocyte cell-derived chemotaxin 224
Mapping the human gut mycobiome in middle-aged and elderly adults: multiomics insights and implications for host metabolic health24
Short-chain fatty acids in patients with severe acute pancreatitis: friend or foe?24
Purastat post-EMR: unresolved questions from the PURPLE trial24
Response to: Correspondence on "PICaSSO Histologic Remission Index (PHRI) in ulcerative colitis: development of a novel simplified histological score for monitoring mucosal healing and predicting clin24
Response to the letter to the editor ‘revisiting lipid dysregulation in colorectal cancer: critical appraisal of pro-inflammatory bias and therapeutic implications’24
Correction:Growth differentiation factor 11 attenuates liver fibrosis via expansion of liver progenitor cells24
Production and possible reduction of greenhouse gases produced during GI endoscopy activity: a systematic review of available literature23
Understanding tissue injury and remodelling in eosinophilic oesophagitis: development towards personalised medicine23
Strengths and limitations of AlphaMissense inCPA1missense variant classification23
Large proximal gastric GIST tumours: downsizing by imatinib and subsequent endoresection23
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