OOIR: Observatory of International Research

Papers

(The H4-Index of Gut is 74. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Defining the key intrahepatic gene networks in HCV infection driven by sex	1594
Picking up microbial clues in early-onset colorectal cancer	1295
Finding a mate for MLCK: improving the potential for therapeutic targeting of gut permeability	883
Immunomodulation and entry inhibition: selgantolimod’s double punch against hepatitis B virus	450
Unusual history of ‘stitch’	308
Response to McAlindon’s letter	276
Unusual case of severe diarrhoea	210
Correction:P97 A patient information bundle outlining dietary advice in liver disease specific to the cost of living crisis improves patient care: ‘Looking after Your Liver for Less’	209
Impact of margin thermal ablation after endoscopic mucosal resection of large (≥20 mm) non-pedunculated colonic polyps on long-term recurrence	206
Holistic healthcare in inflammatory bowel disease: time for patient-centric approaches?	193
Liquid biopsy to identify Barrett’s oesophagus, dysplasia and oesophageal adenocarcinoma: theEMERALDmulticentre study	191
Innumerable nodules in all parts of the small intestine	189
A mucus production programme promotes classical pancreatic ductal adenocarcinoma	184
Perturbation of mRNA splicing in liver cancer: insights, opportunities and challenges	177
Genetically proxied ketohexokinase function and risk of colorectal cancer: a Mendelian randomisation study	172
Crohn’s disease and ulcerative colitis exhibit prediagnostic antibody signatures with shared and divergent changes towards disease onset	172
Establishment of enterically transmitted hepatitis virus animal models using lipid nanoparticle-based full-length viral genome RNA delivery system	169
Mass cytometry-based peripheral blood analysis as a novel tool for early detection of solid tumours: a multicentre study	163
IL-3 receptor signalling suppresses chronic intestinal inflammation by controlling mechanobiology and tissue egress of regulatory T cells	159
S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos	156
Prospective, double-blind diagnostic multicentre study of confocal laser endomicroscopy for wheat sensitivity in patients with irritable bowel syndrome	155
Third Asia-Pacific consensus recommendations on colorectal cancer screening and postpolypectomy surveillance	154
Growth rates and histopathological outcomes of small (6–9 mm) colorectal polyps based on CT colonography surveillance and endoscopic removal	153
Hepatocyte senescence in alcohol-associated hepatitis: epiphenomenon or disease-driving mechanism?	152
Reassessing the prophylactic effect of clip closure to prevent delayed rebleeding after colorectal endoscopic submucosal dissection	148

Absence of a pancreatic microbiome in intraductal papillary mucinous neoplasm	148
Rate of suitable cases for primary EUS-guided biliary drainage in distal malignant biliary obstruction	146
COVID-19 and liver disease	144
Where are we with gastric cancer screening in Europe in 2024?	143
Gut virome-colonisingOrthohepadnavirusgenus is associated with ulcerative colitis pathogenesis and induces intestinal inflammationin vivo	137
HBcrAg values may predict virological and immunological responses to pegIFN-a in NUC-suppressed HBeAg-negative chronic hepatitis B	137
Current therapies and new developments in NASH	132
Autologous regulatory T-cell transfer in refractory ulcerative colitis with concomitant primary sclerosing cholangitis	130
Perplexing case of abdominal pain with eosinophilia and fasciitis	127
Methionine deficiency facilitates antitumour immunity by altering m⁶A methylation of immune checkpoint transcripts	127
Impact of climate change on vulnerable populations	127
Time for arginine methylation: PRMT5 inhibition to advance cholangiocarcinoma treatment	122
Most excess years of potential life loss among individuals with cirrhosis during the pandemic were not related to COVID-19	122
Tumour-intrinsic alterations and stromal matrix remodelling promote Wnt-niche independence during diffuse-type gastric cancer progression	119
New entity of adult ultra-short coeliac disease: the first international cohort and case–control study	116
Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression	112
From clinical trials to clinical practice: how should we design and evaluate prediction models in the care of IBD?	109
24-Nor-ursodeoxycholic acid improves intestinal inflammation by targeting T_H17 pathogenicity and transdifferentiation	108
Correction: Inflammatory cell-derived CXCL3 promotes pancreatic cancer metastasis through a novel myofibroblast-hijacked cancer escape mechanism	107
Reply to: Non-invasive tests and advanced chronic liver disease in NAFLD: two steps forward and one step back?	105
GI highlights from the literature	105
Tiny contributors to severe obesity inside the gut	100
Shaggy white lesion with morphological changes in the oesophagus	100
Host transcriptome signatures in human faecal-washes predict histological remission in patients with IBD	99
Lumen-apposing metal stents versus double-pigtail plastic stents for infected necrotising pancreatitis: more doubts than answers	99
Humoral response to SARS-CoV-2 infection among liver transplant recipients	99
Discovery of the pancreatic basal cell: a new candidate for an adult stem cell emerges	98
Rare cause of obstructive jaundice	97
Endoscopic mucosal and submucosal cutting for long benign oesophageal strictures	96
Engineered anti-PDL1 with IFNα targets both immunoinhibitory and activating signals in the liver to break HBV immune tolerance	95
Reflux conditions induce E-cadherin cleavage and EMT via APE1 redox function in oesophageal adenocarcinoma	94
Faecal occult blood loss accurately predicts future detection of colorectal cancer. A prognostic model	94
Intron-mediated enhancement of SPINK1 expression for pancreatitis therapy	92
Definite benefits of GLP-1 receptor agonists: what is the risk of gastroparesis and lung aspiration?	92
Integrated multimodel analysis of intestinal inflammation exposes key molecular features of preclinical and clinical IBD	91
Selective decontamination of the digestive tract in critically ill children: fighting fire with fire or burning down the house?	90
Gastrointestinal microbiota and inflammasomes interplay in health and disease: a gut feeling	90
Interactive enhancer hubs (iHUBs) mediate transcriptional reprogramming and adaptive resistance in pancreatic cancer	88
Association between appendectomy and Parkinson’s disease from the UK Biobank	86
MicroRNA-223 attenuates hepatocarcinogenesis by blocking hypoxia-driven angiogenesis and immunosuppression	85
Unveiling 8 years of duodenoscope contamination: insights from a retrospective analysis in a large tertiary care hospital	84
Need for standardised approaches to human microbiome research using the example of colorectal neoplasia research	81
British Society of Gastroenterology guidelines on sedation in gastrointestinal endoscopy	80
SARS-CoV-2 vaccination in patients with GI and hepatobiliary carcinoma: a call for booster vaccination	80
Treatment of type 2 diabetes with MASLD: new evidence for personalised medicine	80
Rethinking routine mapping biopsies in gastric intestinal metaplasia: justification for endoscopic stratification	78
Environmental and healthcare trade-offs between single-use and reusable gastroscopes	78
Withdrawal of the British Society of Gastroenterology IBD risk grid for COVID-19 severity	76
Endoscopic stratification of gastric intestinal metaplasia: where are we, where do we want to go and how do we get there?	74