OOIR: Observatory of International Research

Papers

(The TQCC of General and Comparative Endocrinology is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Fetal bovine islets and the discovery of insulin	47
Editorial Board	37
Editorial Board	29
Editorial Board	27
Functional insight and cell-specific expression of the adipokinetic hormone/corazonin-related peptide in the human disease vector mosquito, Aedes aegypti	26
Evaluation of stress response in black-tailed prairie dogs (Cynomys ludovicianus) in arid regions from colonies in Chihuahua Mexico	23
Molecular mechanisms underlying guanylin-induced transcellular Cl− secretion into the intestinal lumen of seawater-acclimated eels	23
Murine fertility and spermatogenesis are independent of the testis-specific Spdye4a gene	22
Expressions of melanopsins in telencephalon imply their function in synchronizing semilunar spawning rhythm in the mudskipper Boleophthalmus pectinirostris	21
The insulin signaling pathway a century after its discovery: Sexual dimorphism in insulin signaling	20
Early-life glucocorticoids accelerate lymphocyte count senescence in roe deer	19
Editorial Board	19
Light/darkness modulation of the hypothalamic-pituitary-ovarian axis in the plains vizcacha, Lagostomus maximus, a seasonal breeding species	18
Melatonin attenuates glucocorticoid effect induced by medroxyprogesterone acetate in rats	18
Sex-specific effects of hatching order on nestling baseline corticosterone in a wild songbird	17
Functional characterization of growth hormone releasing hormone and its receptor in amphioxus with implication for origin of hypothalamic-pituitary axis	17
LPXRFa and its receptor in yellowtail kingfish (Seriola lalandi): Molecular cloning, ontogenetic expression profiles, and stimulatory effects on growth hormone and gonadotropin gene expression	17
Enduring sex-dependent effects of lipopolysaccharide treatment on the hypothalamic–pituitary–gonadal axis in mice	17
Functional characterization of CCHamides and deorphanization of their receptors in the yellow fever mosquito, Aedes aegypti	17
In vivo induction of crown-of-thorns starfish (Acanthaster spp.) spawning using a synthetic relaxin-like gonad-stimulating peptide	16
Tilapia, a good model for studying reproductive endocrinology	16
Role of sex steroids in fish sex determination and differentiation as revealed by gene editing	16
Kobayashi Award 2021: Neuropeptides, receptors, and follicle development in the ascidian, Ciona intestinalis Type A: New clues to the evolution of chordate neuropeptidergic systems from biological nic	16
Growth regulation in brook charr Salvelinus fontinalis	16
Extraembryonic metabolism of corticosterone protects against effects of exposure	15

Hormonology: A kaleidoscopic tale of dedication, serendipity, and ingenuity	15
Effects of faecal inorganic content variability on quantifying glucocorticoid and thyroid hormone metabolites in large felines: Implications for physiological assessments in free-ranging animals	15
Assessment of glucocorticoids, sex steroids, and innate immunity in wild red-eared slider turtles (Trachemys scripta elegans)	15
Hormonal effects on glucose and ketone metabolism in a perfused liver of an elasmobranch, the North Pacific spiny dogfish, Squalus suckleyi	14
Low-temperature-induced disruption of reproductive axis and sperm vitality via stress axis in Monopterus albus	14
Changes in maternal fecal corticosterone metabolites across lactation and in response to chronic stress	14
Pharmacological properties of whale shark (Rhincodon typus) melanocortin-2 receptor and melancortin-5 receptor: Interaction with MRAP1 and MRAP2	14
Evidence from transcriptome analysis unravelled the roles of eyestalk in salinity adaptation in Pacific white shrimp (Litopenaeus vannamei)	14
Variation in feather corticosterone levels in Alpine swift nestlings provides support for the hypo-responsive hypothesis	13
Salivary corticosterone reflects plasmatic levels in a wild seabird	13
Identification of motilin in Japanese fire bellied newt	13
Insulin-like growth factor 1 and the hormonal mediation of sibling rivalry	12
Corrigendum to “Does variation in glucocorticoid concentrations predict fitness? A phylogenetic meta-analysis” [Gen. Comp. Endocrinol. 300 (2021) 113611]	12
Genome-wide identification, phylogeny, expression and eyestalk neuroendocrine regulation of vitellogenin gene family in the freshwater giant prawn Macrobrachium rosenbergii	12
Production of recombinant Japanese eel (Anguilla japonica) growth hormones and their effects on early-stage larvae	12
Molecular mechanisms of the stress-induced regulation of the inflammatory response in fish	12
Distribution of kisspeptin system and its relation with gonadotropin-releasing hormone in the hypothalamus of the South American plains vizcacha, Lagostomus maximus	12
Physiological roles of ghrelin in the regulation of gastrointestinal motility in vertebrates	12
Changes in hypothalamic–pituitary–adrenal axis function, immunity, and glucose during acute Plasmodium relictum infection in house sparrows (Passer domesticus)	11
Estrogen-related receptor functions via the 20-hydroxyecdysone and IIS/TOR signaling pathways to regulate the development and morphology changes of ant Polyrhachis vicina Roger (Hymenoptera, Formicida	11
Editorial Board	11
Resistin in endocrine pancreas of sheep: Presence and expression related to different diets	11
Is there potential for estradiol receptor signaling in lophotrochozoans?	11
Urotensin II in GIFT Nile tilapia (Oreochromis niloticus): CDS cloning, tissue distribution, and in vitro regulation of male reproduction	11
Evaluating suitability of saliva to measure steroid concentrations in grey seal pups	11
Editorial Board	11
Puberty regulation in chub mackerel Scomber japonicus, an important aquaculture fish species, via reproductive endocrine mechanism	11
In vivo effect of recombinant Fsh and Lh administered to meagre (Argyrosomus regius) at the initial stages of sex differentiation	11
In vitro effects of polychlorinated biphenyls and their hydroxylated metabolites on the synthesis and metabolism of iodothyronines in the chicken (Gallus domesticus) thyroid gland	11
Catecholamines modulate differentially nonapeptide precursor mRNA expression in the preoptic area and ovary of the catfish Heteropneustes fossilis: An in vitro study	10
The neurosecretory staining in the pleural-pedal ganglion of the Japanese abalone (Ezoawabi), Haliotis discus hannai, and its relationship to reproduction; with a description of a newly observed neuro	10
Nesfatin-1-like peptide is a negative regulator of cardiovascular functions in zebrafish and goldfish	10
Zebra finches (Taeniopygia castanotis) display varying degrees of stress resilience in response to constant light	10
Influence of season, age, sex, and time of day on the endocrine profile of the common bottlenose dolphin (Tursiops truncatus)	10
Editorial Board	10
Strong regulatory effects of vgll3 genotype on reproductive axis gene expression in juvenile male Atlantic salmon	10
Long-term monitoring of egg-laying cycle using ultrasonography reveals the reproductive dynamics of circulating sex steroids in an oviparous catshark, Scyliorhinus torazame	10
Editorial Board	10
Molecular form identification of anterior pituitary gland-secreted prolactin in chicken	10
Small GTPase control of pituitary hormone secretion: Evidence from studies in the goldfish (Carassius auratus) neuroendocrine model	10
Characterization of myoinhibitory peptide signaling system and its implication in larval metamorphosis and spawning behavior in Pacific abalone	10
Hepatic estrogen-responsive genes relating to oogenesis in cutthroat trout (Oncorhynchus clarki): The transcriptional induction in primary cultured hepatocytes and the in vitro promoter transactivatio	10
Activation of the Cap’n’collar C pathway (Nrf2 pathway in vertebrates) signaling in insulin pathway compromised Drosophila melanogaster flies ameliorates the diabetic state upon pro-oxidant conditions	9
Editorial Board	9
Molecular characterization and stage-dependent gene expression of gonadotropin receptors in Pacific bluefin tuna, Thunnus orientalis, ovarian follicles	9
Molecular characterization and ontogenetic expression profiles of LPXRFa and its receptor in Japanese flounder (Paralichthys olivaceus)	9
Prolactin and the evolution of male pregnancy	9
Characterization of a crustacean hyperglycemic hormone of the horsehair crab Erimacrus isenbeckii	9
Role and mechanism of the p-JAK2/p-STAT3 signaling pathway in follicular development in PCOS rats	9
Identification and functional analysis of six melanocortin-4-receptor-like (MC4R-like) mutations in goldfish (Carassius auratus)	9

Sex steroid profiles align with phenotype in sex-reversed female lizards	9
Testosterone concentration coincides with distance travelled in the free-ranging male Saharan sand-viper, Cerastes vipera	9
Global analysis of ligand-gated ion channel conservation across Platyhelminthes	9
Variation in nest building, aggression, learning, and steroid hormone levels in Betta splendens	9
Coping with extremes: High-altitude sparrows enhance metabolic and thermogenic capacities in the pectoralis muscle and suppress in the liver relative to their lowland counterparts	8
Killer whale fecal samples: How to get the most out of a single extraction	8
Gene expression in the hypothalamic-pituitary-thyroid axis in Seriola rivoliana early larvae development at different temperatures	8
Vasotocin expression is associated with social preference development of the medaka fish	8
Analysis of evolutionary and functional features of the bullfrog SULT1 family	8
Hypothalamic-pituitary-adrenal axis regulation and organization in urban and rural song sparrows	8
Comparative transcriptomic analysis and genome-wide characterization of the Semaphorin family reveal the potential mechanism of angiogenesis around embryo in ovoviviparous black rockfish (Sebastes sch	8
The chondrichthyan glucagon-like peptide 3 regulates hepatic ketone metabolism in the Pacific spiny dogfish Squalus suckleyi	8
RNA-Seq analysis offers insight into the TBBPA-DHEE-induced endocrine-disrupting effect and neurotoxicity in juvenile zebrafish (Danio rerio)	8
Using transcriptome analysis to investigate the induction of vitellogenesis in female Japanese eels (Anguilla japonica)	8
Fostered offspring develop hyper-reactive endocrine stress responses in a plural-breeding rodent, Octodon degus	8
Corrigendum to “The uterus masculinus of the Eurasian beaver (Castor fiber L.) – The appraisal of fast hormone regulation by membrane androgen and estrogen receptors involvement” [Gen. Comp. Endocrino	8
Elevated expression of inhibin α gene in sterile allotriploid crucian carp	7
Editorial Board	7
Motilin is a regulator of gastric contraction in Japanese fire belly newts (Cynops pyrrhogaster), in vitro studies using isolated gastrointestinal strips of newts, rabbits, and chickens	7
Pre-breeding androgen and glucocorticoid profiles in the eastern hellbender salamander (Cryptobranchus alleganiensis alleganiensis)	7
Urbanization and maternal hormone transfer: Endocrine and morphological phenotypes across ontogenetic stages	7
Molecular and pharmacological analysis of the melanocortin-2 receptor and its accessory proteins Mrap1 and Mrap2 in a Squalomorph shark, the Pacific spiny dogfish	7
Cortisol production by interrenal cells in rainbow trout (Oncorhynchus mykiss) is stimulated by 5-HT4 receptor activation	7
Editorial Board	7
The stress response in Atlantic salmon (Salmo salar L.): identification and functional characterization of the corticotropin-releasing factor (crf) paralogs	7
Hair glucocorticoids are not a historical marker of stress – Exploring the time-scale of corticosterone incorporation into hairs in a rat model	7
Regulation of melanocortin-5 receptor pharmacology by two isoforms of MRAP2 in ricefield eel (Monopterus albus)	7
Editorial Board	7
The hormonal and neural control of egg production in the historically important model insect, Rhodnius prolixus: A review, with new insights in this post-genomic era	7
Transcriptional regulation of CYP19A1 expression in chickens: ESR1, ESR2 and NR5A2 form a functional network	7
Editorial Board	7
Editorial Board	6
Biocompatible polymeric microparticles serve as novel and reliable vehicles for exogenous hormone manipulations in passerines	6
Early development of the glucocorticoid stress response in dyeing poison frog tadpoles	6
Comparative transcriptome provides insights into differentially expressed genes between testis and ovary of Onychostoma macrolepis in reproduction period	6
Progesterone receptors in extratesticular ducts of the Amazonian stingray Potamotrygon wallacei: A potential role in sperm maturation and aggregate formation	6
CRISPR/Cas9-induced LEAP2 and GHSR1a knockout mutant zebrafish displayed abnormal growth and impaired lipid metabolism	6
Fecal adrenal hormone patterns during ovulatory and non-ovulatory reproductive cycles in female veiled chameleons (Chamaeleo calyptratus)	6
Knockout of tac3 genes in zebrafish shows no impairment of reproduction	6
Neuromodulation in the fish brain for reproductive success	6
Influence of EE2 exposure, age and sex on telomere length in European long-snouted seahorse (Hippocampus guttulatus)	6
Enhanced expression of Cyp17a1 and production of DHEA-S in the liver of late-pregnant rats	6
Association of seasonal changes in circulating cortisol concentrations with the expression of cortisol biosynthetic enzymes and a glucocorticoid receptor in the blubber of common bottlenose dolphin	6
Potential role of DNA methylation of cyp19a1a promoter during sex change in protogynous orange-spotted grouper, Epinephelus coioides	6
Neurosecretory protein GL in GIFT tilapia (Oreochromis niloticus): cDNA cloning, tissue distribution and effects of feeding on its expression	6
Editorial Board	6
Editorial Board	6
Genome-wide analysis of two different regions of brain reveals the molecular changes of fertility related genes in rln3a-/- mutants in male Nile tilapia (Oreochromis niloticus)	6
Identification and functional characterization of gonadotropin -releasing hormone in pompano (Trachinotus ovatus)	6
A comparative account of nesfatin-1 in vertebrates	6
The distribution of gonadotropin-inhibitory hormone (GnIH) and its receptor in zebra finch (Taeniopygia guttata) spinal cord	6
Investigating the utility of using fecal hormone metabolites as a reproductive management tool for captive short-beaked echidnas (Tachyglossus aculeatus)	6
Possible effects of the central adrenergic and dopaminergic receptors on hypophagia induced by neuromedin S in neonatal layer-type chicks	5
Evolutionary loss of the β1-adrenergic receptor in salmonids	5
Absence of some cytochrome P450 (CYP) and hydroxysteroid dehydrogenase (HSD) enzymes in hagfishes	5
Two phases of gonadal sex differentiation in zebrafish with ZZ/ZW sex determination system	5
An updated look at the mating system, parental care and androgen seasonal variations in ratites	5
Differential regulation of hepatic SH3 domain binding kinase 1 (SBK1) expression in mouse and goldfish	5
Identification and characterization of neuropeptides in sea urchin Strongylocentrotus intermedius	5
Editorial Board	5
Metamorphosis-associated immune system maturation in Senegalese sole	5
Editorial Board	5
The effect of androgen exposure on cerebral lateralization in the American alligator (Alligator mississippiensis)	5
Two ACTH analogs exert differential effects on monocytes/macrophages function regulation in ayu (Plecoglossus altivelis)	5
Structural modeling and gene expression analysis of phosvitinless vitellogenin (vgc) in the Indian freshwater murrel, Channa punctatus (Bloch, 1793)	5
Tpo knockout in zebrafish partially recapitulates clinical manifestations of congenital hypothyroidism and reveals the involvement of TH in proper development of glucose homeostasis	5
Trends in the evolution of the elasmobranch melanocortin-2 receptor: Insights from structure/function studies on the activation of whale shark Mc2r	5
Characterization and localization of relaxin-like gonad-stimulating peptide in the crown-of-thorns starfish, Acanthaster cf. solaris	5
Cholecystokinin and gastrin-releasing peptide differentially inhibit appetite of rainbow trout	5
Using an on-site laboratory for fecal steroid analysis in wild white-faced capuchins	5
Effects and action mechanism of gonadotropins on ovarian follicular cells: A novel role of Sphingosine-1-Phosphate (S1P). A review	5
The Japan Society for Comparative Endocrinology (JSCE) awards	5
Editorial Board	5
Presence of GnRH3 in sturgeon and the roles of GnRH1 and GnRH2 on the regulation of LH/FSH in mature female sterlet Acipenser ruthenus in vitro	5
Are hair cortisol levels dependent on hair growth rate? A pilot study in rhesus macaques	5
Mechanistic study of transcription factor Sox18 during heart development	5