FEBS Letters

Papers
(The TQCC of FEBS Letters is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)
ArticleCitations
Front Cover156
Front Cover111
A two‐step mechanism for the binding of the HIV‐1 MPER epitope by the 10E8 antibody onto biosensor‐supported lipid bilayers61
55
ArabidopsisRAN GTPases are critical for mitosis during male and female gametogenesis55
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The bacterial MRE11RAD50 and DNA247
Reciprocal control of viral infection and phosphoinositide dynamics45
Heparin promotes rapid fibrillation of the basic parathyroid hormone at physiological pH44
Molecular and mechanical mechanisms of animal cell abscission43
Mapping secondary substrate‐binding sites on the GH11 xylanase from Bacillus subtilis42
Interdomain electron transfer in flavohaemoglobin from Candida norvegensis with antibiotic azole compounds39
Artificial miRNAs derived from miR‐181 family members have potential in cancer therapy due to an altered spectrum of target mRNAs39
The fatty acid synthase inhibitor C75 differentially affects the adipogenic differentiation of multipotent cells and preadipocytes39
CRK and NCK adaptors may functionally overlap in zebrafish neurodevelopment, as indicated by common binding partners and overlapping expression patterns39
miR‐4734 conditionally suppresses ER stress‐associated proinflammatory responses39
Valosin‐containing protein regulates the stability of fused in sarcoma granules in cells by changing ATP concentrations38
Mycobacterium tuberculosis low molecular weight T‐cell antigen Mtb8.4 has heme‐binding and fiber‐forming properties38
Insight into the function of the Golgi membrane protein GOLM1 in cholangiocytes through interactomic analysis36
Silica‐coated magnetic nanobeads in a flow enrichment target capture Halbach ( FETCH ) magnetic separation system for circulating tumor cell enrichme35
Mice deficient in the phosphatase activity of sEH show decreased levels of the endocannabinoid 2‐ AG 34
Clinical and mechanistic insights into the roles of DDX41 in haematological malignancies34
Purification tags markedly affect self‐aggregation of CPEB334
Mechanisms and kinetic assays of aminoacyl‐ tRNA synthetases32
Microscopic modulation and analysis of islets of Langerhans in living zebrafish larvae32
The inhibitory SAPS3AMPK interaction detected in HEK293 32
Cytochrome bd‐I from Escherichia coli is catalytically active in the absence of the CydH subunit32
The ubiquitin–proteasome system and autophagy mutually interact in neurotoxin‐induced dopaminergic cell death models of Parkinson's disease31
Skraban‐Deardorff intellectual disability syndrome‐associated mutations in WDR 26 impair CTLH E 3 31
Spatial regulation of ARL3 and GSF ‐mediated lipidated cargo trafficking in the primary cilium31
Front Cover30
Promiscuous activity of β‐carotene hydroxylase CrtZ on epoxycarotenoids leads to the formation of rare carotenoids with 6‐hydroxy‐3‐keto‐ε‐ends30
30
Novel insights into autophagosome biogenesis revealed by cryo‐electron tomography30
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Cordycepin generally inhibits growth factor signal transduction in a systems pharmacology study30
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Unlocking the biochemical secrets of longevity: balancing healthspan and lifespan29
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Site‐specific functional roles of the Factor X activation peptide in the intrinsic tenase‐mediated Factor X activation29
Structural and functional insights of itaconyl‐CoA hydratase from Pseudomonas aeruginosa highlight a novel N‐terminal hotdog fold29
The 19S proteasome subunit Rpt5 reversibly associates with cold‐stable microtubules in glial cells at low temperatures29
Generation of novel anti‐apo E monoclonal antibodies that selectively recognize apo E isoforms28
Intron‐oriented HTLV ‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 28
Fluorescence‐based CRISPR interference system for controlled genetic repression and live single‐cell imaging in mycobacteria27
Siderophore specificities of the Pseudomonas aeruginosa TonB‐dependent transporters ChtA and ActA27
Retraction statement: miR ‐518b is down‐regulated, and involved in cell proliferation and invasion by targeting Rap1b in esophageal squamous cell car27
Autophagy in the regulation of cancer dormancy27
Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy27
Solving the protein folding problem…26
A working model for cytoplasmic assembly of H/ ACA snoRNPs26
A novel approach to single‐cell analysis reveals intrinsic differences in immune marker expression in unstimulated BALB/c and C57BL/6 macrophages25
Homocysteine thiolactone and H2O2 induce amino acid modifications and alter the fibrillation propensity of the Aβ25–35 peptide24
Interorgan crosstalk mechanisms in disease: the case of acute kidney injury‐induced remote lung injury24
Cas9‐Geminin and Cdt1‐fused anti‐CRISPR protein synergistically increase editing accuracy24
Mechanisms of interorgan crosstalk in health and disease23
Cell culture pioneer Jaroslav Cinatl—the pursuit and defence of truth23
MyD88 and not TRIF knockout is sufficient to abolish LPS‐induced inflammatory responses in bone‐derived macrophages22
Elucidation of interface interactions between a dehydratase domain and an acyl carrier protein in cremimycin polyketide synthase22
PAT m RNA decapping factors are required for proper development in Arabidopsis22
Insights into PI3K / AKT signaling in B cell development and chronic lymphocytic leukemia22
Human phytanoyl‐CoA dioxygenase domain‐containing 1 (PHYHD1) is a putative oxygen sensor associated with RNA and carbohydrate metabolism22
Neuronostatin regulates proliferation and differentiation of rat brown primary preadipocytes21
RANBP2 evolution and human disease21
Does the nuclear envelope retain its identity during mitosis?20
Front Cover20
Fanzors, a family of eukaryotic RNA‐guided DNA endonucleases20
Why science education is more important than most scientists think20
20
Characterizing the amino acid activation center of the naturally editing‐deficient aminoacyl‐tRNA synthetase PheRS in Mycoplasma mobile20
20
It's a two‐way street: Photoswitching and reversible changes of the protein matrix in photoswitchable fluorescent proteins and bacteriophytochromes20
The age‐related decline of helicase function—how G‐quadruplex structures promote genome instability19
Coordinating nucleoporin condensation and nuclear pore complex assembly19
A novel perspective on the role of nucleus accumbens neurons in encoding associative learning19
The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity19
Disrupting the interaction between a p53 gain‐of‐function mutant and the transcriptional co‐activator PC4 reverses drug resistance in cancer cells19
Kit structural mutations associated with the porcine dominant white phenotype impair hematopoiesis in mice18
The Melolontha melolontha entomopoxvirus fusolin protein is a chitin‐active lytic polysaccharide monooxygenase that displays extreme stability18
A highly active S1‐P1 nuclease from the opportunistic pathogen Stenotrophomonas maltophilia cleaves c‐di‐GMP18
The enigmatic world of tear extracellular vesicles (EVs)–exploring their role in ocular health and beyond18
Structural basis for substrate and antibiotic recognition by Helicobacter pylori isoleucyl‐t RNA synth18
Molecular determinants of lipid droplet subpopulations and their fates18
Membranes that make fat: roles of membrane lipids as acyl donors for triglyceride synthesis and organelle function18
The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases18
SARSC o V ‐2‐derived protein Orf9b enhances 17
Gly56 in the synthetic site of isoleucyl‐tRNA synthetase confers specificity and maintains communication with the editing site17
Heteromerization between α1B‐adrenoceptor and chemokine (C‐C motif) receptor 2 biases α1B‐adrenoceptor signaling: Implications for vascular funct17
Structural differences in the outer membrane‐associated flagellar rings between sheathed and unsheathed flagella17
THAP 3 recruits SMYD 3 to OXPHOS genes and epigenetically promotes 17
Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment17
Social context prevents heat hormetic effects against mutagens during fish development17
A scorpion toxin affecting sodium channels shows double cistrans isomerism17
The cytochrome oxidase defect in ISC ‐depleted yeast is caused by impaired iron–sulfur cluster maturation of the mitoribosome assembly factor Rsm2217
STAT3 transcriptionally regulates the expression of genes related to glycogen metabolism in developing motor neurons16
Membrane occupation and recognition nexus (MORN) motif controls protein localization and function16
Small GTPase signaling hubs at the surface of cellular membranes in physiology and disease16
The role of Lin28A and Lin28B in cancer beyond Let‐716
The BcsD subunit of type I bacterial cellulose synthase interacts dynamically with the BcsAB catalytic core complex16
Transcription‐coupled DNA repair protects genome stability upon oxidative stress‐derived DNA stran16
Front Cover15
Front Cover15
Front Cover15
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Front Cover14
GENIGMA: an app to map the 3D genome of cancer cell lines through extreme citizen science14
Predicting genome‐wide tissue‐specific enhancers via combinatorial transcription factor genomic occupancy analysis14
The roles of molecular chaperones in regulating cell metabolism14
A coiled‐coil domain triggers oligomerization of MmpL10 , the mycobacterial transporter of trehalose polyphleate precursor14
Middle East respiratory syndrome coronavirus ORF4b protein inhibits TLR7‐ and TLR9‐dependent alpha interferon induction14
14
Acetylation stabilises calmodulin‐regulated calcium signalling14
Senile plaques in Alzheimer's disease arise from Aβ‐ and Cathepsin D‐enriched mixtures leaking out during intravascular haemolysis and microaneurysm rupture14
EGTA ‐induced disruption of adherens junctions in zebrafish embryonic epidermis14
Endothelial lipase‐binding peptides similar to netrin‐1 inhibit hepatitis B virus infection14
Retraction Statement: miR‐188 promotes senescence of lineage‐negative bone marrow cells by targeting MAP3K3 expression14
GCN2 kinase‐mediated upregulation of ubiquitin C maintains intracellular glutamine level and tRNAGln(CUG) charging under amino acid starvation14
Front Cover14
Unorthodox regulation of the MglA Ras‐like GTPase controlling polarity in Myxococcus xanthus14
Interferon‐induced protein ISG15 in the central nervous system, quo vadis?14
13
Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl113
Tumour suppressor p53 inhibits hepatitis C virus replication by inducing E6AP‐mediated proteasomal degradation of the viral core protein13
Crystal structure of a novel heterooligomeric aminotransferase from Serratia sp. ATCC 39006 provides i13
Lipid droplets and fatty acid‐induced lipotoxicity: in a nutshell13
Abiogenesis through gradual evolution of autocatalysis into template‐based replication13
Bioinspired and biomolecular catalysts for energy conversion and storage13
The 3D‐structure, kinetics and dynamics of the E. coli nitroreductase NfsA with NADP+ provide glimpses of its catalytic mechanism13
Photosystems and photoreceptors in cyanobacterial phototaxis and photophobotaxis13
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 113
From the sideline: Tissue‐specific nucleoporin function in health and disease, an update13
ATG and ESCRT control multiple modes of microautophagy13
Retraction statement: MicroRNA‐520g induces epithelial‐mesenchymal transition and promotes metastasis of hepatocellular carcinoma by targeting SMAD713
Deacylases—structure, function, and relationship to diseases13
Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury13
MiR‐15b‐5p inhibits castration‐resistant growth of prostate cancer cells by targeting the muscarinic cholinergic receptor CHRM313
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells13
Targeting RNA‐binding proteins with small molecules: Perspectives, pitfalls and bifunctional molecules13
The clinically relevant triple mutation in the mtND1 gene inactivates Escherichia coli complex I12
Integrin β1 transduces the signal for LY6D‐induced macropinocytosis and mediates senescence‐inducing stress‐evoked vacuole formation via FAK12
12
The mechanics of the heart: zooming in on hypertrophic cardiomyopathy and cMyBP‐C12
Autophagy in a Nutshell12
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Lipocalin 2 inhibits actin glutathionylation to promote invasion and migration12
Yeast Sec14‐like lipid transfer proteins Pdr16 and Pdr17 bind and transfer the ergosterol precursor lanosterol in addition to phosphatidylinositol12
Advances in the development of organoid‐based models of the trachea and esophagus11
Molecular characterization of a moss isoprene synthase provides insight into its evolution11
Front Cover11
Hypoxanthine‐guanine phosphoribosyltransferase is activated via positive cooperativity between guanine and IMP11
Temperature adaptation of yeast phospholipid molecular species at the acyl chain positional level11
Sticholysin I–II oligomerization in the absence of membranes11
Mobile zinc as a modulator of sensory perception11
Structural and functional insights into the enzymatic activities of lipases from Burkholderia stagnalis and Burkholderia plantarii11
GABARAP interacts with EGFR — supporting the unique role of this hAtg8 protein during receptor trafficking11
Autophagy in cancer and protein conformational disorders11
Amy and Friends: improving the lives of individuals affected by DNA repair disorders11
Odz4 upregulates SAN ‐specific genes to promote differentiation into cardiac pacemaker‐like cells11
Charged sequence motifs increase the propensity towards liquid–liquid phase separation11
STAP ‐2 negatively regulates BCR ‐mediated B cell activation by recruiting tyrosine‐protein kinase 11
Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification11
Autophagy as a caretaker of nuclear integrity11
Krüppel‐like factor 6 participates in extravillous trophoblast cell differentiation and its expression is reduced in abnormally invasive placenta11
Release of FUS into the extracellular space is regulated by its amino‐terminal prion‐like domain11
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum11
The survival grip–how cell adhesion promotes tumor maintenance within the microenvironment11
Human WIPI β‐propeller function in autophagy and neurodegeneration10
Front Cover10
Front Cover10
A new approach to making scientific research more efficient – rethinking sustainability10
Nucleocytoplasmic transport at the crossroads of proteostasis, neurodegeneration and neuroprotection10
Front Cover10
The dual nature of TDC – bridging dendritic and T cells in immunity10
Endocytic proteins mediating GPR15 receptor internalization provide insight into the underlying mechanisms10
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F‐actin determines the time‐dependent shift in docking dynamics of glucagon‐like peptide‐1 granules upon stimulation of secretion10
The interaction of PD ‐1/ PDL1 and its inhib10
The deubiquitinase USP10 mediates crosstalk between the LKB1/AMPK axis and Wnt/β‐catenin signaling in cancer10
Thiol redox switches regulate the oligomeric state of cyanobacterial Rre1, RpaA and RpaB response regulators10
A nanoemulsified formulation of dolutegravir and epigallocatechin gallate inhibits HIV‐1 replication in cellular models10
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The winner of the 2024 FEBS Letters Award—an interview with Rachel Flynn10
Function‐driven design of a surrogate interleukin‐2 receptor ligand10
EXPRESSION OF CONCERN: Introgression of a Novel Salt‐Tolerant L‐Myo‐Inositol 1‐Phosphate Synthase from Porteresia Coarctata (Roxb.) Tateoka (PcINO1) Confers Salt Tolera10
Structural determinants for membrane binding of the EGFR juxtamembrane domain10
Cis ‐regulatory evolution underlying the changes in wingless expression pattern associated with wing pigmentation of 10
Nuclear pore complex and nucleocytoplasmic transport disruption in neurodegeneration9
Deletion of the transcription factors Hsf1, Msn2 and Msn4 in yeast uncovers transcriptional reprogramming in response to proteotoxic stress9
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization9
Clues to transcription/replication collision‐induced DNA damage: it was RNAP , in the chromosome, 9
Front Cover9
Front Cover9
The FEBS 60th anniversary writing contest—blueprints for the scientific society of tomorrow9
9
Diacylglycerol kinase ε depletion suppresses LPS ‐stimulated NFκB9
Overactivation of the androgen receptor exacerbates gravid uterine ferroptosis via interaction with and suppression of the NRF2 defense signaling pathway9
Clinically observed deletions in SARS‐CoV‐2 Nsp1 affect its stability and ability to inhibit translation9
Mechanisms of parasite‐mediated disruption of brain vessels9
The prolyl hydroxylase OGFOD1 promotes cancer cell proliferation by regulating the expression of cell cycle regulators9
Characterization of molecular mechanisms of CaMKKα/1 oligomerization9
Front Cover9
RETRACTION: Theaflavins Retard Human Breast Cancer Cell Migration by Inhibiting NF‐κB via p53‐ROS Cross‐talk9
Blueprints for the scientific society of the future: how FEBS and other scientific societies will have changed 60 years from now9
Evidence for partial functional overlap of KEA and MSL transport proteins in the chloroplast inner9
Mitochondrial permeability transition mediated by MTCH2 and F‐ ATP synthase contributes to ferropt9
Succinate oxidation rescues mitochondrial ATP synthesis at high temperature in Drosophila melanogaster9
Front Cover9
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LIM protein Ajuba promotes liver cell proliferation through its involvement in DNA replication and DNA damage control9
You are who your friends are—nuclear pore proteins as components of chromatin‐binding complexes9
Front Cover9
Brain lipidomic profiles of sleep enhancement through co‐administration of alprazolam and CGS216808
Arabidopsis mutants lacking DLDG1 and non‐photochemical quenching‐related proteins reveal the regulatory role of DLDG1 in chloroplast pH homeostasis8
Hidden biochemical fossils reveal an evolutionary trajectory for glycolysis in the prebiotic era8
Phosphoinositides in membrane remodeling during infections and cellular stresses8
Five problems plaguing publishing in the life sciences—and one common cause8
Strigolactone biosynthesis in rice can occur via a 9‐cis‐3‐OH‐10′‐apo‐β‐carotenal intermediate8
Conjugative transfer of the I nc N plasmid p KM 8
Knockout of the BRAP homolog in mice leads to abnormal tracheal cilia8
Does Lactobacillus reuteri influence ergothioneine levels in the human body?8
C9orf72 ALS ‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules8
HNF4α overexpression enhances the therapeutic potential of umbilical cord mesenchymal stem/stromal cells in mice with acute liver failure8
Liver gene transfer for metabolite detoxification in inherited metabolic diseases8
EZH2 modulates retinoic acid signaling to ensure myotube formation during development8
The scorpion toxin BeKm‐1 blocks hERG cardiac potassium channels using an indispensable arginine residue8
Dissecting the Ca 2+ dependence of DesA1 function in Mycobacterium tuberculosis8
Analytical methods and tools for studying inositol phosphates8
Transcription as a double‐edged sword in genome maintenance8
Binding mechanism of adenylate kinase‐specific monobodies8
The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation8
Two phosphoenolpyruvate carboxykinases with differing biochemical properties in Chlamydomonas reinhardtii8
ABC transporter activity is affected by the size of lipid nanodiscs8
The structure of a Lactobacillus helveticus chlorogenic acid esterase and the dynamics of its insertion domain provide insights into substrate binding8
Comparative characterization of nine novel GH51, GH54 and GH62 α‐l‐arabinofuranosidases from Penicillium subrubescens8
Urinary microRNA profiling in pregnant women identifies placental microRNAs that are candidate biomarkers for monitoring placental health8
A γ‐glutamyl hydrolase lacking the signal peptide confers susceptibility to folates/antifolates in acute lymphoblastic leukemia cells8
Quinone chemistry in respiratory complex I involves protonation of a conserved aspartic acid residue8
RETRACTION : Role of the PDK1PKBGSK37
Adding hydrophobicity or positive charges to the cytosolic half of the α‐synuclein 3–11 helix increases membrane association and S129 phosphorylation7
Structural basis of a GatC ortholog transporter in the bacterial phosphotransferase system7
Deubiquitinases at the interplay between hematopoietic stem cell aging and myelodysplastic transformation7
A life‐time of hematopoietic cell function: ascent, stability, and decline7
Circulating histones as clinical biomarkers in critically ill conditions7
Development of visible light‐sensitive human neuropsin ( OPN5 ) via single amino acid substitution7
Endomembrane‐mediated storage protein trafficking in plants: Golgi‐dependent or Golgi‐independent?7
Exogenous fatty acids inhibit fatty acid synthesis by competing with endogenously generated substrates for phospholipid synthesis in Escherichia coli7
Structural basis for the minimal bifunctional alginate epimerase AlgE3 from Azotobacter chroococcum7
Transcription factor EB controls both motogenic and mitogenic cell activities7
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