FEBS Letters

Papers
(The TQCC of FEBS Letters is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
Front Cover81
Front Cover78
68
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The inhibitory SAPS3AMPK interaction detected in HEK293 62
Mechanisms and kinetic assays of aminoacyl‐ tRNA synthetases60
Insight into the function of the Golgi membrane protein GOLM1 in cholangiocytes through interactomic analysis60
Artificial miRNAs derived from miR‐181 family members have potential in cancer therapy due to an altered spectrum of target mRNAs49
Molecular and mechanical mechanisms of animal cell abscission48
Cytochrome bd‐I from Escherichia coli is catalytically active in the absence of the CydH subunit48
Heparin promotes rapid fibrillation of the basic parathyroid hormone at physiological pH47
Mice deficient in the phosphatase activity of sEH show decreased levels of the endocannabinoid 2‐ AG 46
Silica‐coated magnetic nanobeads in a flow enrichment target capture Halbach ( FETCH ) magnetic separation system for circulating tumor cell enrichme45
The bacterial MRE11RAD50 and DNA245
Cordycepin generally inhibits growth factor signal transduction in a systems pharmacology study45
miR‐4734 conditionally suppresses ER stress‐associated proinflammatory responses44
Spatial regulation of ARL3 and GSF ‐mediated lipidated cargo trafficking in the primary cilium41
Clinical and mechanistic insights into the roles of DDX41 in haematological malignancies41
The crystal structure of the TPR domain of the EccA5 ATPase and demonstration of its interaction w39
Novel insights into autophagosome biogenesis revealed by cryo‐electron tomography39
The dual role of lectins in cancer—immunotherapy tools and therapeutic targets38
Skraban‐Deardorff intellectual disability syndrome‐associated mutations in WDR 26 impair CTLH E 3 38
Deubiquitinase USP2 promotes hepatic stellate cell activation via p300 stabilization38
Design and analysis strategies for robust microbiome ageing research36
CRK and NCK adaptors may functionally overlap in zebrafish neurodevelopment, as indicated by common binding partners and overlapping expression patterns35
A two‐step mechanism for the binding of the HIV‐1 MPER epitope by the 10E8 antibody onto biosensor‐supported lipid bilayers35
Purification tags markedly affect self‐aggregation of CPEB335
The ubiquitin–proteasome system and autophagy mutually interact in neurotoxin‐induced dopaminergic cell death models of Parkinson's disease34
Mapping secondary substrate‐binding sites on the GH11 xylanase from Bacillus subtilis33
Reciprocal control of viral infection and phosphoinositide dynamics33
CPEB3 selectively inhibits α‐synuclein aggregation without modulating TDP ‐43 pathology32
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Front Cover29
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28
A working model for cytoplasmic assembly of H/ ACA snoRNPs28
Intron‐oriented HTLV ‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 28
Cell culture pioneer Jaroslav Cinatl—the pursuit and defence of truth27
RANBP2 evolution and human disease27
Unlocking the biochemical secrets of longevity: balancing healthspan and lifespan27
Structural and functional insights of itaconyl‐CoA hydratase from Pseudomonas aeruginosa highlight a novel N‐terminal hotdog fold27
Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions27
Elucidation of interface interactions between a dehydratase domain and an acyl carrier protein in cremimycin polyketide synthase27
Siderophore specificities of the Pseudomonas aeruginosa TonB‐dependent transporters ChtA and ActA27
Front Cover26
Solving the protein folding problem…25
Cas9‐Geminin and Cdt1‐fused anti‐CRISPR protein synergistically increase editing accuracy25
Retraction statement: miR ‐518b is down‐regulated, and involved in cell proliferation and invasion by targeting Rap1b in esophageal squamous cell car24
Homocysteine thiolactone and H2O2 induce amino acid modifications and alter the fibrillation propensity of the Aβ25–35 peptide24
PAT m RNA decapping factors are required for proper development in Arabidopsis24
A novel approach to single‐cell analysis reveals intrinsic differences in immune marker expression in unstimulated BALB/c and C57BL/6 macrophages23
Generation of novel anti‐apo E monoclonal antibodies that selectively recognize apo E isoforms23
Phosphoinositides and inositol phosphates as molecular glues23
Exploring the potential of AlphaFold distograms for predicting binding‐induced hinge motions23
Human phytanoyl‐CoA dioxygenase domain‐containing 1 (PHYHD1) is a putative oxygen sensor associated with RNA and carbohydrate metabolism23
Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy22
Atomic force microscopy‐based nanomechanical signatures as cancer biomarkers in a nutshell21
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates21
Insights into PI3K / AKT signaling in B cell development and chronic lymphocytic leukemia21
Protein disulfide isomerase dissolves and detoxifies oligomeric assemblies of amyloid beta peptide21
Fluorescence‐based CRISPR interference system for controlled genetic repression and live single‐cell imaging in mycobacteria21
Autophagy in the regulation of cancer dormancy21
MyD88 and not TRIF knockout is sufficient to abolish LPS‐induced inflammatory responses in bone‐derived macrophages21
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Does the nuclear envelope retain its identity during mitosis?20
Front Cover20
Plasmodium falciparum ring‐infected erythrocyte surface antigen 3 ( PfRESA3 ) is a cytoskeleton‐interacting protein and po20
The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity19
STAT3 transcriptionally regulates the expression of genes related to glycogen metabolism in developing motor neurons19
A highly active S1‐P1 nuclease from the opportunistic pathogen Stenotrophomonas maltophilia cleaves c‐di‐GMP19
Small GTPase signaling hubs at the surface of cellular membranes in physiology and disease19
Kit structural mutations associated with the porcine dominant white phenotype impair hematopoiesis in mice19
It's a two‐way street: Photoswitching and reversible changes of the protein matrix in photoswitchable fluorescent proteins and bacteriophytochromes19
The age‐related decline of helicase function—how G‐quadruplex structures promote genome instability19
A novel perspective on the role of nucleus accumbens neurons in encoding associative learning18
A scorpion toxin affecting sodium channels shows double cistrans isomerism18
The Melolontha melolontha entomopoxvirus fusolin protein is a chitin‐active lytic polysaccharide monooxygenase that displays extreme stability18
THAP 3 recruits SMYD 3 to OXPHOS genes and epigenetically promotes 18
Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment18
Neuronostatin regulates proliferation and differentiation of rat brown primary preadipocytes18
Gly56 in the synthetic site of isoleucyl‐tRNA synthetase confers specificity and maintains communication with the editing site18
SARSC o V ‐2‐derived protein Orf9b enhances 18
Membranes that make fat: roles of membrane lipids as acyl donors for triglyceride synthesis and organelle function17
Disrupting the interaction between a p53 gain‐of‐function mutant and the transcriptional co‐activator PC4 reverses drug resistance in cancer cells17
Ischemic heart disease‐associated ∆ M1Q91 PDE5A2 mutant shows reduced efficacy for 17
Social context prevents heat hormetic effects against mutagens during fish development17
Structural differences in the outer membrane‐associated flagellar rings between sheathed and unsheathed flagella17
The enigmatic world of tear extracellular vesicles (EVs)–exploring their role in ocular health and beyond16
The cytochrome oxidase defect in ISC ‐depleted yeast is caused by impaired iron–sulfur cluster maturation of the mitoribosome assembly factor Rsm2216
Structural basis for substrate and antibiotic recognition by Helicobacter pylori isoleucyl‐t RNA synth16
Heteromerization between α1B‐adrenoceptor and chemokine (C‐C motif) receptor 2 biases α1B‐adrenoceptor signaling: Implications for vascular funct16
Transcription‐coupled DNA repair protects genome stability upon oxidative stress‐derived DNA stran16
Fanzors, a family of eukaryotic RNA‐guided DNA endonucleases15
15
Front Cover15
The role of Lin28A and Lin28B in cancer beyond Let‐715
The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases15
Molecular determinants of lipid droplet subpopulations and their fates15
Diversity and complexity in neural organoids15
Coordinating nucleoporin condensation and nuclear pore complex assembly15
The BcsD subunit of type I bacterial cellulose synthase interacts dynamically with the BcsAB catalytic core complex15
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Front Cover14
Endothelial lipase‐binding peptides similar to netrin‐1 inhibit hepatitis B virus infection14
Front Cover14
Retraction Statement: miR‐188 promotes senescence of lineage‐negative bone marrow cells by targeting MAP3K3 expression14
Abiogenesis through gradual evolution of autocatalysis into template‐based replication14
Front Cover14
Middle East respiratory syndrome coronavirus ORF4b protein inhibits TLR7‐ and TLR9‐dependent alpha interferon induction14
Bioinspired and biomolecular catalysts for energy conversion and storage14
MiR‐15b‐5p inhibits castration‐resistant growth of prostate cancer cells by targeting the muscarinic cholinergic receptor CHRM314
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Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells14
Targeting RNA‐binding proteins with small molecules: Perspectives, pitfalls and bifunctional molecules14
Interaction and co‐phase separation of SARSCoV ‐2 nucleocapsid protein and human 13
EGTA ‐induced disruption of adherens junctions in zebrafish embryonic epidermis13
Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury13
Predicting genome‐wide tissue‐specific enhancers via combinatorial transcription factor genomic occupancy analysis13
Photosystems and photoreceptors in cyanobacterial phototaxis and photophobotaxis13
The roles of molecular chaperones in regulating cell metabolism13
The THO complex in Schizosaccharomyces pombe —dissecting the composition and functional hierarchy13
Crystal structure of a novel heterooligomeric aminotransferase from Serratia sp. ATCC 39006 provides i13
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 113
A coiled‐coil domain triggers oligomerization of MmpL10 , the mycobacterial transporter of trehalose polyphleate precursor13
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Senile plaques in Alzheimer's disease arise from Aβ‐ and Cathepsin D‐enriched mixtures leaking out during intravascular haemolysis and microaneurysm rupture13
Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl113
GCN2 kinase‐mediated upregulation of ubiquitin C maintains intracellular glutamine level and tRNAGln(CUG) charging under amino acid starvation13
Interferon‐induced protein ISG15 in the central nervous system, quo vadis?12
ATG and ESCRT control multiple modes of microautophagy12
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Deacylases—structure, function, and relationship to diseases12
From the sideline: Tissue‐specific nucleoporin function in health and disease, an update12
Odz4 upregulates SAN ‐specific genes to promote differentiation into cardiac pacemaker‐like cells12
Valosin‐containing protein counteracts ATP ‐driven dissolution of FUS condensates through its 12
Tumour suppressor p53 inhibits hepatitis C virus replication by inducing E6AP‐mediated proteasomal degradation of the viral core protein12
Lipid droplets and fatty acid‐induced lipotoxicity: in a nutshell12
Unorthodox regulation of the MglA Ras‐like GTPase controlling polarity in Myxococcus xanthus12
Mobile zinc as a modulator of sensory perception11
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum11
Autophagy in a Nutshell11
GABARAP interacts with EGFR — supporting the unique role of this hAtg8 protein during receptor trafficking11
Endocytic proteins mediating GPR15 receptor internalization provide insight into the underlying mechanisms11
Front Cover11
Release of FUS into the extracellular space is regulated by its amino‐terminal prion‐like domain11
Yeast Sec14‐like lipid transfer proteins Pdr16 and Pdr17 bind and transfer the ergosterol precursor lanosterol in addition to phosphatidylinositol11
Human WIPI β‐propeller function in autophagy and neurodegeneration11
The survival grip–how cell adhesion promotes tumor maintenance within the microenvironment11
Structural and functional insights into the enzymatic activities of lipases from Burkholderia stagnalis and Burkholderia plantarii11
Advances in the development of organoid‐based models of the trachea and esophagus11
Integrin β1 transduces the signal for LY6D‐induced macropinocytosis and mediates senescence‐inducing stress‐evoked vacuole formation via FAK11
Cis ‐regulatory evolution underlying the changes in wingless expression pattern associated with wing pigmentation of 11
A nanoemulsified formulation of dolutegravir and epigallocatechin gallate inhibits HIV‐1 replication in cellular models11
Amy and Friends: improving the lives of individuals affected by DNA repair disorders11
Structural biology of ferritin nanocages10
Autophagy as a caretaker of nuclear integrity10
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The dual nature of TDC – bridging dendritic and T cells in immunity10
Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification10
Autophagy in cancer and protein conformational disorders10
STAP ‐2 negatively regulates BCR ‐mediated B cell activation by recruiting tyrosine‐protein kinase 10
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The winner of the 2024 FEBS Letters Award—an interview with Rachel Flynn10
Lipocalin 2 inhibits actin glutathionylation to promote invasion and migration10
Temperature adaptation of yeast phospholipid molecular species at the acyl chain positional level10
The Mycobacterium tuberculosis ESAT ‐6 protein inhibits differentiation of human monocytes to dendritic cells10
Front Cover10
Molecular characterization of a moss isoprene synthase provides insight into its evolution10
An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase9
The interaction of PD ‐1/ PDL1 and its inhib9
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Nucleocytoplasmic transport at the crossroads of proteostasis, neurodegeneration and neuroprotection9
Front Cover9
EXPRESSION OF CONCERN : Introgression of a Novel Salt‐Tolerant L‐ Myo ‐Inositol 1‐Phosphate Synthase from 9
Inhibition of mitochondrial NADH :ubiquinone oxidoreductase by spinning oscillating magnetic fields causes toxicity in cancer cells9
Deletion of the transcription factors Hsf1, Msn2 and Msn4 in yeast uncovers transcriptional reprogramming in response to proteotoxic stress9
Succinate oxidation rescues mitochondrial ATP synthesis at high temperature in Drosophila melanogaster9
Function‐driven design of a surrogate interleukin‐2 receptor ligand9
Diacylglycerol kinase ε depletion suppresses LPS ‐stimulated NFκB9
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization9
The deubiquitinase USP10 mediates crosstalk between the LKB1/AMPK axis and Wnt/β‐catenin signaling in cancer9
A new approach to making scientific research more efficient – rethinking sustainability9
Structural determinants for membrane binding of the EGFR juxtamembrane domain9
The prolyl hydroxylase OGFOD1 promotes cancer cell proliferation by regulating the expression of cell cycle regulators9
Conserved structural motifs in PAS , LOV , and CRY 9
Mechanisms of parasite‐mediated disruption of brain vessels9
Front Cover9
Inhibiting stearoyl‐ CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR 8
Five problems plaguing publishing in the life sciences—and one common cause8
Phosphoinositides in membrane remodeling during infections and cellular stresses8
Front Cover8
You are who your friends are—nuclear pore proteins as components of chromatin‐binding complexes8
The FEBS 60th anniversary writing contest—blueprints for the scientific society of tomorrow8
Clues to transcription/replication collision‐induced DNA damage: it was RNAP , in the chromosome, 8
Investigating transcription factor dynamics in health and disease using FRAP8
Nuclear pore complex and nucleocytoplasmic transport disruption in neurodegeneration8
F‐actin determines the time‐dependent shift in docking dynamics of glucagon‐like peptide‐1 granules upon stimulation of secretion8
Front Cover8
PDIA1 promotes androgen receptor activation and prostate cancer cell survival through enhancing HMMR stability8
Arabidopsis mutants lacking DLDG1 and non‐photochemical quenching‐related proteins reveal the regulatory role of DLDG1 in chloroplast pH homeostasis8
Liver gene transfer for metabolite detoxification in inherited metabolic diseases8
Quinone chemistry in respiratory complex I involves protonation of a conserved aspartic acid residue8
Characterization of molecular mechanisms of CaMKKα/1 oligomerization8
Urinary microRNA profiling in pregnant women identifies placental microRNAs that are candidate biomarkers for monitoring placental health8
Front Cover8
Brain lipidomic profiles of sleep enhancement through co‐administration of alprazolam and CGS216808
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Evidence for partial functional overlap of KEA and MSL transport proteins in the chloroplast inner8
RETRACTION : Role of Phospholemman and the 70 kDa Inhibitor Protein in Regulating Na + 8
Direct interaction between tubulin and PMCA , a complex with functional implications8
Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides8
Two phosphoenolpyruvate carboxykinases with differing biochemical properties in Chlamydomonas reinhardtii8
Conjugative transfer of the I nc N plasmid p KM 8
The scorpion toxin BeKm‐1 blocks hERG cardiac potassium channels using an indispensable arginine residue8
Dissecting the Ca 2+ dependence of DesA1 function in Mycobacterium tuberculosis8
Transcription as a double‐edged sword in genome maintenance8
Front Cover8
C9orf72 ALS ‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules8
Blueprints for the scientific society of the future: how FEBS and other scientific societies will have changed 60 years from now8
HNF4α overexpression enhances the therapeutic potential of umbilical cord mesenchymal stem/stromal cells in mice with acute liver failure8
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ABL drives phosphorylation of Semaphorin 6 A at conserved tyrosines necessary for zebrafish retinal maintenance8
RETRACTION : Theaflavins Retard Human Breast Cancer Cell Migration by Inhibiting NF‐κB via p53‐ROS Cross‐talk8
Mitochondrial permeability transition mediated by MTCH2 and F‐ ATP synthase contributes to ferropt8
Knockout of the BRAP homolog in mice leads to abnormal tracheal cilia8
Strigolactone biosynthesis in rice can occur via a 9‐cis‐3‐OH‐10′‐apo‐β‐carotenal intermediate8
Analytical methods and tools for studying inositol phosphates8
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing7
Small RNA sequencing in hypoxic naked mole‐rat hearts suggests microRNA regulation of RNA‐ and translation‐related processes7
The radical impact of oxygen on prokaryotic evolution—enzyme inhibition first, uninhibited essential biosyntheses second, aerobic respiration third7
Motif‐guided trafficking of leishmanial PAS domain‐containing phosphoglycerate kinase into glycosomes and lysosomes7
Transforming science communication through storytelling7
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Structural basis for the minimal bifunctional alginate epimerase AlgE3 from Azotobacter chroococcum7
Development of visible light‐sensitive human neuropsin ( OPN5 ) via single amino acid substitution7
A life‐time of hematopoietic cell function: ascent, stability, and decline7
ABC transporter activity is affected by the size of lipid nanodiscs7
A Pellino‐2 variant is associated with constitutive NLRP3 inflammasome activation in a family with ocular pterygium–digital keloid dysplasia7
Front Cover7
Front Cover7
Spontaneous and chaperone‐assisted metal loading in the active site of protein phosphatase‐17
TNFR2 signaling promotes monocytic‐ MDSC differentiation and production of immunosuppressive mediators7
'The world needs science, and science needs women'…but what do women in science need? – interviews and panel discussion with 5 outstanding female scientists7
The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation7
Binding mechanism of adenylate kinase‐specific monobodies7
AAA + protein unfoldases—the Moirai of the proteome7
Poliovirus capsid protein VP3 can penetrate vascular endothelial cells7
Corrigendum: His‐163 is a stereospecific proton donor in the mechanism of d ‐glucosaminate‐6‐phosphate ammonia‐lyase7
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