FEBS Letters

Papers
(The median citation count of FEBS Letters is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
Front Cover69
Front Cover68
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Microscopic modulation and analysis of islets of Langerhans in living zebrafish larvae57
The inhibitory SAPS3AMPK interaction detected in HEK293 54
Mechanisms and kinetic assays of aminoacyl‐ tRNA synthetases49
CRK and NCK adaptors may functionally overlap in zebrafish neurodevelopment, as indicated by common binding partners and overlapping expression patterns46
Mycobacterium tuberculosis low molecular weight T‐cell antigen Mtb8.4 has heme‐binding and fiber‐forming properties45
Insight into the function of the Golgi membrane protein GOLM1 in cholangiocytes through interactomic analysis44
Artificial miRNAs derived from miR‐181 family members have potential in cancer therapy due to an altered spectrum of target mRNAs43
Molecular and mechanical mechanisms of animal cell abscission43
Clinical and mechanistic insights into the roles of DDX41 in haematological malignancies42
Cytochrome bd‐I from Escherichia coli is catalytically active in the absence of the CydH subunit41
ArabidopsisRAN GTPases are critical for mitosis during male and female gametogenesis40
A two‐step mechanism for the binding of the HIV‐1 MPER epitope by the 10E8 antibody onto biosensor‐supported lipid bilayers40
Mice deficient in the phosphatase activity of sEH show decreased levels of the endocannabinoid 2‐ AG 39
Cordycepin generally inhibits growth factor signal transduction in a systems pharmacology study38
Purification tags markedly affect self‐aggregation of CPEB337
The bacterial MRE11RAD50 and DNA237
The ubiquitin–proteasome system and autophagy mutually interact in neurotoxin‐induced dopaminergic cell death models of Parkinson's disease36
CPEB3 selectively inhibits α‐synuclein aggregation without modulating TDP ‐43 pathology36
The crystal structure of the TPR domain of the EccA5 ATPase and demonstration of its interaction w36
Silica‐coated magnetic nanobeads in a flow enrichment target capture Halbach ( FETCH ) magnetic separation system for circulating tumor cell enrichme34
miR‐4734 conditionally suppresses ER stress‐associated proinflammatory responses33
The fatty acid synthase inhibitor C75 differentially affects the adipogenic differentiation of multipotent cells and preadipocytes33
Mapping secondary substrate‐binding sites on the GH11 xylanase from Bacillus subtilis33
Novel insights into autophagosome biogenesis revealed by cryo‐electron tomography32
Heparin promotes rapid fibrillation of the basic parathyroid hormone at physiological pH32
Reciprocal control of viral infection and phosphoinositide dynamics31
30
Spatial regulation of ARL3 and GSF ‐mediated lipidated cargo trafficking in the primary cilium30
Skraban‐Deardorff intellectual disability syndrome‐associated mutations in WDR 26 impair CTLH E 3 30
Deubiquitinase USP2 promotes hepatic stellate cell activation via p300 stabilization30
Front Cover28
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Fluorescence‐based CRISPR interference system for controlled genetic repression and live single‐cell imaging in mycobacteria27
MyD88 and not TRIF knockout is sufficient to abolish LPS‐induced inflammatory responses in bone‐derived macrophages27
Intron‐oriented HTLV ‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 27
Autophagy in the regulation of cancer dormancy27
Generation of novel anti‐apo E monoclonal antibodies that selectively recognize apo E isoforms26
A working model for cytoplasmic assembly of H/ ACA snoRNPs25
Human phytanoyl‐CoA dioxygenase domain‐containing 1 (PHYHD1) is a putative oxygen sensor associated with RNA and carbohydrate metabolism25
Protein disulfide isomerase dissolves and detoxifies oligomeric assemblies of amyloid beta peptide25
Insights into PI3K / AKT signaling in B cell development and chronic lymphocytic leukemia24
Cell culture pioneer Jaroslav Cinatl—the pursuit and defence of truth24
A novel approach to single‐cell analysis reveals intrinsic differences in immune marker expression in unstimulated BALB/c and C57BL/6 macrophages24
Structural and functional insights of itaconyl‐CoA hydratase from Pseudomonas aeruginosa highlight a novel N‐terminal hotdog fold24
Elucidation of interface interactions between a dehydratase domain and an acyl carrier protein in cremimycin polyketide synthase23
RANBP2 evolution and human disease23
Unlocking the biochemical secrets of longevity: balancing healthspan and lifespan23
Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions22
Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy22
Solving the protein folding problem…21
Siderophore specificities of the Pseudomonas aeruginosa TonB‐dependent transporters ChtA and ActA21
Cas9‐Geminin and Cdt1‐fused anti‐CRISPR protein synergistically increase editing accuracy21
PAT m RNA decapping factors are required for proper development in Arabidopsis21
Front Cover21
Homocysteine thiolactone and H2O2 induce amino acid modifications and alter the fibrillation propensity of the Aβ25–35 peptide20
Retraction statement: miR ‐518b is down‐regulated, and involved in cell proliferation and invasion by targeting Rap1b in esophageal squamous cell car20
The role of Lin28A and Lin28B in cancer beyond Let‐719
Front Cover19
Exploring the potential of AlphaFold distograms for predicting binding‐induced hinge motions19
Heteromerization between α1B‐adrenoceptor and chemokine (C‐C motif) receptor 2 biases α1B‐adrenoceptor signaling: Implications for vascular funct19
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Atomic force microscopy‐based nanomechanical signatures as cancer biomarkers in a nutshell19
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Does the nuclear envelope retain its identity during mitosis?19
Coordinating nucleoporin condensation and nuclear pore complex assembly18
Molecular determinants of lipid droplet subpopulations and their fates18
Fanzors, a family of eukaryotic RNA‐guided DNA endonucleases18
STAT3 transcriptionally regulates the expression of genes related to glycogen metabolism in developing motor neurons18
Small GTPase signaling hubs at the surface of cellular membranes in physiology and disease18
Plasmodium falciparum ring‐infected erythrocyte surface antigen 3 ( PfRESA3 ) is a cytoskeleton‐interacting protein and po18
The age‐related decline of helicase function—how G‐quadruplex structures promote genome instability18
Kit structural mutations associated with the porcine dominant white phenotype impair hematopoiesis in mice18
Transcription‐coupled DNA repair protects genome stability upon oxidative stress‐derived DNA stran17
The cytochrome oxidase defect in ISC ‐depleted yeast is caused by impaired iron–sulfur cluster maturation of the mitoribosome assembly factor Rsm2217
A highly active S1‐P1 nuclease from the opportunistic pathogen Stenotrophomonas maltophilia cleaves c‐di‐GMP17
Neuronostatin regulates proliferation and differentiation of rat brown primary preadipocytes17
Gly56 in the synthetic site of isoleucyl‐tRNA synthetase confers specificity and maintains communication with the editing site17
The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity17
THAP 3 recruits SMYD 3 to OXPHOS genes and epigenetically promotes 17
The BcsD subunit of type I bacterial cellulose synthase interacts dynamically with the BcsAB catalytic core complex17
The Melolontha melolontha entomopoxvirus fusolin protein is a chitin‐active lytic polysaccharide monooxygenase that displays extreme stability17
It's a two‐way street: Photoswitching and reversible changes of the protein matrix in photoswitchable fluorescent proteins and bacteriophytochromes17
A novel perspective on the role of nucleus accumbens neurons in encoding associative learning17
Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment16
Social context prevents heat hormetic effects against mutagens during fish development16
Structural basis for substrate and antibiotic recognition by Helicobacter pylori isoleucyl‐t RNA synth16
A scorpion toxin affecting sodium channels shows double cistrans isomerism16
Disrupting the interaction between a p53 gain‐of‐function mutant and the transcriptional co‐activator PC4 reverses drug resistance in cancer cells16
The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases16
SARSC o V ‐2‐derived protein Orf9b enhances 16
Structural differences in the outer membrane‐associated flagellar rings between sheathed and unsheathed flagella16
Diversity and complexity in neural organoids16
The enigmatic world of tear extracellular vesicles (EVs)–exploring their role in ocular health and beyond15
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Front Cover15
Membranes that make fat: roles of membrane lipids as acyl donors for triglyceride synthesis and organelle function15
Front Cover15
Front Cover15
Ischemic heart disease‐associated ∆ M1Q91 PDE5A2 mutant shows reduced efficacy for 15
Front Cover15
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Front Cover14
Retraction Statement: miR‐188 promotes senescence of lineage‐negative bone marrow cells by targeting MAP3K3 expression14
Senile plaques in Alzheimer's disease arise from Aβ‐ and Cathepsin D‐enriched mixtures leaking out during intravascular haemolysis and microaneurysm rupture14
Middle East respiratory syndrome coronavirus ORF4b protein inhibits TLR7‐ and TLR9‐dependent alpha interferon induction14
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells14
MiR‐15b‐5p inhibits castration‐resistant growth of prostate cancer cells by targeting the muscarinic cholinergic receptor CHRM314
The THO complex in Schizosaccharomyces pombe —dissecting the composition and functional hierarchy14
Bioinspired and biomolecular catalysts for energy conversion and storage14
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Unorthodox regulation of the MglA Ras‐like GTPase controlling polarity in Myxococcus xanthus14
Tumour suppressor p53 inhibits hepatitis C virus replication by inducing E6AP‐mediated proteasomal degradation of the viral core protein14
Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury14
Endothelial lipase‐binding peptides similar to netrin‐1 inhibit hepatitis B virus infection14
Crystal structure of a novel heterooligomeric aminotransferase from Serratia sp. ATCC 39006 provides i13
EGTA ‐induced disruption of adherens junctions in zebrafish embryonic epidermis13
A coiled‐coil domain triggers oligomerization of MmpL10 , the mycobacterial transporter of trehalose polyphleate precursor13
GCN2 kinase‐mediated upregulation of ubiquitin C maintains intracellular glutamine level and tRNAGln(CUG) charging under amino acid starvation13
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 113
Predicting genome‐wide tissue‐specific enhancers via combinatorial transcription factor genomic occupancy analysis13
The roles of molecular chaperones in regulating cell metabolism13
Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl113
Photosystems and photoreceptors in cyanobacterial phototaxis and photophobotaxis13
Deacylases—structure, function, and relationship to diseases13
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Interferon‐induced protein ISG15 in the central nervous system, quo vadis?12
Interaction and co‐phase separation of SARSCoV ‐2 nucleocapsid protein and human 12
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Structural and functional insights into the enzymatic activities of lipases from Burkholderia stagnalis and Burkholderia plantarii12
From the sideline: Tissue‐specific nucleoporin function in health and disease, an update12
The 3D‐structure, kinetics and dynamics of the E. coli nitroreductase NfsA with NADP+ provide glimpses of its catalytic mechanism12
ATG and ESCRT control multiple modes of microautophagy12
Odz4 upregulates SAN ‐specific genes to promote differentiation into cardiac pacemaker‐like cells12
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum12
Valosin‐containing protein counteracts ATP ‐driven dissolution of FUS condensates through its 12
Targeting RNA‐binding proteins with small molecules: Perspectives, pitfalls and bifunctional molecules12
Abiogenesis through gradual evolution of autocatalysis into template‐based replication12
Endocytic proteins mediating GPR15 receptor internalization provide insight into the underlying mechanisms12
Lipid droplets and fatty acid‐induced lipotoxicity: in a nutshell12
Cis ‐regulatory evolution underlying the changes in wingless expression pattern associated with wing pigmentation of 11
Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification11
Amy and Friends: improving the lives of individuals affected by DNA repair disorders11
Yeast Sec14‐like lipid transfer proteins Pdr16 and Pdr17 bind and transfer the ergosterol precursor lanosterol in addition to phosphatidylinositol11
Integrin β1 transduces the signal for LY6D‐induced macropinocytosis and mediates senescence‐inducing stress‐evoked vacuole formation via FAK11
Human WIPI β‐propeller function in autophagy and neurodegeneration11
Advances in the development of organoid‐based models of the trachea and esophagus11
STAP ‐2 negatively regulates BCR ‐mediated B cell activation by recruiting tyrosine‐protein kinase 11
Front Cover11
Molecular characterization of a moss isoprene synthase provides insight into its evolution11
The survival grip–how cell adhesion promotes tumor maintenance within the microenvironment11
Mobile zinc as a modulator of sensory perception11
A nanoemulsified formulation of dolutegravir and epigallocatechin gallate inhibits HIV‐1 replication in cellular models11
GABARAP interacts with EGFR — supporting the unique role of this hAtg8 protein during receptor trafficking11
Autophagy as a caretaker of nuclear integrity11
Release of FUS into the extracellular space is regulated by its amino‐terminal prion‐like domain11
Temperature adaptation of yeast phospholipid molecular species at the acyl chain positional level10
Structural biology of ferritin nanocages10
Front Cover10
Front Cover10
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The Mycobacterium tuberculosis ESAT ‐6 protein inhibits differentiation of human monocytes to dendritic cells10
Autophagy in cancer and protein conformational disorders10
The dual nature of TDC – bridging dendritic and T cells in immunity10
EXPRESSION OF CONCERN : Introgression of a Novel Salt‐Tolerant L‐ Myo ‐Inositol 1‐Phosphate Synthase from 10
Autophagy in a Nutshell10
Lipocalin 2 inhibits actin glutathionylation to promote invasion and migration10
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The winner of the 2024 FEBS Letters Award—an interview with Rachel Flynn10
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An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase9
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization9
Mechanisms of parasite‐mediated disruption of brain vessels9
Deletion of the transcription factors Hsf1, Msn2 and Msn4 in yeast uncovers transcriptional reprogramming in response to proteotoxic stress9
Front Cover9
Evidence for partial functional overlap of KEA and MSL transport proteins in the chloroplast inner9
The interaction of PD ‐1/ PDL1 and its inhib9
Nuclear pore complex and nucleocytoplasmic transport disruption in neurodegeneration9
F‐actin determines the time‐dependent shift in docking dynamics of glucagon‐like peptide‐1 granules upon stimulation of secretion9
The deubiquitinase USP10 mediates crosstalk between the LKB1/AMPK axis and Wnt/β‐catenin signaling in cancer9
Conserved structural motifs in PAS , LOV , and CRY 9
Inhibition of mitochondrial NADH :ubiquinone oxidoreductase by spinning oscillating magnetic fields causes toxicity in cancer cells9
ABL drives phosphorylation of Semaphorin 6 A at conserved tyrosines necessary for zebrafish retinal maintenance9
The prolyl hydroxylase OGFOD1 promotes cancer cell proliferation by regulating the expression of cell cycle regulators9
Function‐driven design of a surrogate interleukin‐2 receptor ligand9
Mitochondrial permeability transition mediated by MTCH2 and F‐ ATP synthase contributes to ferropt9
Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides9
A new approach to making scientific research more efficient – rethinking sustainability9
Structural determinants for membrane binding of the EGFR juxtamembrane domain9
Nucleocytoplasmic transport at the crossroads of proteostasis, neurodegeneration and neuroprotection9
Diacylglycerol kinase ε depletion suppresses LPS ‐stimulated NFκB9
Clues to transcription/replication collision‐induced DNA damage: it was RNAP , in the chromosome, 9
Succinate oxidation rescues mitochondrial ATP synthesis at high temperature in Drosophila melanogaster8
Arabidopsis mutants lacking DLDG1 and non‐photochemical quenching‐related proteins reveal the regulatory role of DLDG1 in chloroplast pH homeostasis8
C9orf72 ALS ‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules8
Dissecting the Ca 2+ dependence of DesA1 function in Mycobacterium tuberculosis8
ABC transporter activity is affected by the size of lipid nanodiscs8
Strigolactone biosynthesis in rice can occur via a 9‐cis‐3‐OH‐10′‐apo‐β‐carotenal intermediate8
Characterization of molecular mechanisms of CaMKKα/1 oligomerization8
Front Cover8
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Blueprints for the scientific society of the future: how FEBS and other scientific societies will have changed 60 years from now8
The structure of a Lactobacillus helveticus chlorogenic acid esterase and the dynamics of its insertion domain provide insights into substrate binding8
Brain lipidomic profiles of sleep enhancement through co‐administration of alprazolam and CGS216808
You are who your friends are—nuclear pore proteins as components of chromatin‐binding complexes8
The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation8
HNF4α overexpression enhances the therapeutic potential of umbilical cord mesenchymal stem/stromal cells in mice with acute liver failure8
Knockout of the BRAP homolog in mice leads to abnormal tracheal cilia8
Front Cover8
The FEBS 60th anniversary writing contest—blueprints for the scientific society of tomorrow8
Front Cover8
Motif‐guided trafficking of leishmanial PAS domain‐containing phosphoglycerate kinase into glycosomes and lysosomes8
Conjugative transfer of the I nc N plasmid p KM 8
Binding mechanism of adenylate kinase‐specific monobodies8
Urinary microRNA profiling in pregnant women identifies placental microRNAs that are candidate biomarkers for monitoring placental health8
Five problems plaguing publishing in the life sciences—and one common cause8
Analytical methods and tools for studying inositol phosphates8
RETRACTION : Theaflavins Retard Human Breast Cancer Cell Migration by Inhibiting NF‐κB via p53‐ROS Cross‐talk8
Front Cover8
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Two phosphoenolpyruvate carboxykinases with differing biochemical properties in Chlamydomonas reinhardtii8
Liver gene transfer for metabolite detoxification in inherited metabolic diseases7
The role and implications of mammalian cellular circadian entrainment7
Small RNA sequencing in hypoxic naked mole‐rat hearts suggests microRNA regulation of RNA‐ and translation‐related processes7
Deubiquitinases at the interplay between hematopoietic stem cell aging and myelodysplastic transformation7
Transforming science communication through storytelling7
A guide for blood–brain barrier models7
The radical impact of oxygen on prokaryotic evolution—enzyme inhibition first, uninhibited essential biosyntheses second, aerobic respiration third7
The scorpion toxin BeKm‐1 blocks hERG cardiac potassium channels using an indispensable arginine residue7
Corrigendum: His‐163 is a stereospecific proton donor in the mechanism of d ‐glucosaminate‐6‐phosphate ammonia‐lyase7
Development of visible light‐sensitive human neuropsin ( OPN5 ) via single amino acid substitution7
Age‐associated myeloid malignancies – the role of STAT3 and STAT5 in myelodysplastic syndrome and 7
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A Pellino‐2 variant is associated with constitutive NLRP3 inflammasome activation in a family with ocular pterygium–digital keloid dysplasia7
Roles of methionine and cysteine residues of the Escherichia coli sensor kinase HprS in reactive chlorine species sensing7
Transcription as a double‐edged sword in genome maintenance7
Phosphoinositides in membrane remodeling during infections and cellular stresses7
The acyl‐CoA‐binding protein Acb1 regulates mitochondria, lipid droplets, and cell proliferation7
Quinone chemistry in respiratory complex I involves protonation of a conserved aspartic acid residue7
Front Cover7
Reducing plastic waste in scientific protocols by 65% — practical steps for sustainable research7
Spontaneous and chaperone‐assisted metal loading in the active site of protein phosphatase‐17
Human PHOSPHO1 exhibits phosphatidylcholine‐ and phosphatidylethanolamine‐phospholipase C activities and interacts with diacylglycerol kinase δ7
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing7
LIM protein Ajuba promotes liver cell proliferation through its involvement in DNA replication and DNA damage control7
Hidden biochemical fossils reveal an evolutionary trajectory for glycolysis in the prebiotic era7
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