FEBS Letters

Article	Citations
Art and Science break boundaries in The Garden of Earthly Delights	107
Artificial miRNAs derived from miR‐181 family members have potential in cancer therapy due to an altered spectrum of target mRNAs	81
miR‐4734 conditionally suppresses ER stress‐associated proinflammatory responses	67
Clinical and mechanistic insights into the roles of DDX41 in haematological malignancies	49
Front Cover	46
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Cytochrome bd‐I from Escherichia coli is catalytically active in the absence of the CydH subunit	45
Valosin‐containing protein regulates the stability of fused in sarcoma granules in cells by changing ATP concentrations	43
Interdomain electron transfer in flavohaemoglobin from Candida norvegensis with antibiotic azole compounds	43
Mycobacterium tuberculosis low molecular weight T‐cell antigen Mtb8.4 has heme‐binding and fiber‐forming properties	42
The fatty acid synthase inhibitor C75 differentially affects the adipogenic differentiation of multipotent cells and preadipocytes	38
Front Cover	37
Molecular and mechanical mechanisms of animal cell abscission	36
Cordycepin generally inhibits growth factor signal transduction in a systems pharmacology study	36
The ubiquitin–proteasome system and autophagy mutually interact in neurotoxin‐induced dopaminergic cell death models of Parkinson's disease	34
Novel insights into autophagosome biogenesis revealed by cryo‐electron tomography	33
A two‐step mechanism for the binding of the HIV‐1 MPER epitope by the 10E8 antibody onto biosensor‐supported lipid bilayers	33
ArabidopsisRAN GTPases are critical for mitosis during male and female gametogenesis	32
Silica‐coated magnetic nanobeads in a flow enrichment target capture Halbach (FETCH) magnetic separation system for circulating tumor cell enrichment	32
CRK and NCK adaptors may functionally overlap in zebrafish neurodevelopment, as indicated by common binding partners and overlapping expression patterns	31
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Heparin promotes rapid fibrillation of the basic parathyroid hormone at physiological pH	30
Mapping secondary substrate‐binding sites on the GH11 xylanase from Bacillus subtilis	30
Mice deficient in the phosphatase activity of sEH show decreased levels of the endocannabinoid 2‐AG in the olfactory bulb and depressive‐like behavior	30
Localization of the ubiquitin ligase Dma1 to the fission yeast contractile ring is modulated by phosphorylation	29

Insight into the function of the Golgi membrane protein GOLM1 in cholangiocytes through interactomic analysis	29
Skraban‐Deardorff intellectual disability syndrome‐associated mutations in WDR26 impair CTLH E3 complex assembly	29
Fluorescence‐based CRISPR interference system for controlled genetic repression and live single‐cell imaging in mycobacteria	28
Microscopic modulation and analysis of islets of Langerhans in living zebrafish larvae	28
Front Cover	28
Promiscuous activity of β‐carotene hydroxylase CrtZ on epoxycarotenoids leads to the formation of rare carotenoids with 6‐hydroxy‐3‐keto‐ε‐ends	28
A novel approach to single‐cell analysis reveals intrinsic differences in immune marker expression in unstimulated BALB/c and C57BL/6 macrophages	27
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia	27
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The 19S proteasome subunit Rpt5 reversibly associates with cold‐stable microtubules in glial cells at low temperatures	26
Structural and functional insights of itaconyl‐CoA hydratase from Pseudomonas aeruginosa highlight a novel N‐terminal hotdog fold	25
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PAT mRNA decapping factors are required for proper development in Arabidopsis	24
Presenting the FEBS Letters virtual issue on vesicle biology	24
Class A G protein‐coupled receptors assemble into functional higher‐order hetero‐oligomers	23
Reactivity of γ‐glutamyl‐cysteine with intracellular and extracellular glutathione metabolic enzymes	23
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Cas9‐Geminin and Cdt1‐fused anti‐CRISPR protein synergistically increase editing accuracy	23
Front Cover	23
MyD88 and not TRIF knockout is sufficient to abolish LPS‐induced inflammatory responses in bone‐derived macrophages	22
Interorgan crosstalk mechanisms in disease: the case of acute kidney injury‐induced remote lung injury	22
Human phytanoyl‐CoA dioxygenase domain‐containing 1 (PHYHD1) is a putative oxygen sensor associated with RNA and carbohydrate metabolism	22
Generation of novel anti‐apoE monoclonal antibodies that selectively recognize apoE isoforms	22
HutT functions as the major L‐histidine transporter in Pseudomonas putida KT2440	21
Mechanisms of interorgan crosstalk in health and disease	21
Retraction statement: miR‐518b is down‐regulated, and involved in cell proliferation and invasion by targeting Rap1b in esophageal squamous cell carcinoma.	21
Unlocking the biochemical secrets of longevity: balancing healthspan and lifespan	21
‘GutFeel’: an in silico method for predicting gut health status based on the metabolic functional capabilities of the resident microbiome	21
Solving the protein folding problem…	21
Siderophore specificities of the Pseudomonas aeruginosa TonB‐dependent transporters ChtA and ActA	21
Site‐specific functional roles of the Factor X activation peptide in the intrinsic tenase‐mediated Factor X activation	21
Homocysteine thiolactone and H2O2 induce amino acid modifications and alter the fibrillation propensity of the Aβ25–35 peptide	21
Elucidation of interface interactions between a dehydratase domain and an acyl carrier protein in cremimycin polyketide synthase	20
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RANBP2 evolution and human disease	20
Front Cover	19
A scorpion toxin affecting sodium channels shows double cis–trans isomerism	18
Membranes that make fat: roles of membrane lipids as acyl donors for triglyceride synthesis and organelle function	18
Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment	18
Gly56 in the synthetic site of isoleucyl‐tRNA synthetase confers specificity and maintains communication with the editing site	18
Disrupting the interaction between a p53 gain‐of‐function mutant and the transcriptional co‐activator PC4 reverses drug resistance in cancer cells	18
Small GTPase signaling hubs at the surface of cellular membranes in physiology and disease	18
Why science education is more important than most scientists think	18
Front Cover	18
An updated classification and mechanistic insights into ligand binding of the substrate‐binding proteins	18
A novel perspective on the role of nucleus accumbens neurons in encoding associative learning	17
Social context prevents heat hormetic effects against mutagens during fish development	17
Structural differences in the outer membrane‐associated flagellar rings between sheathed and unsheathed flagella	17
Fanzors, a family of eukaryotic RNA‐guided DNA endonucleases	17
The BcsD subunit of type I bacterial cellulose synthase interacts dynamically with the BcsAB catalytic core complex	17

Heteromerization between α1B‐adrenoceptor and chemokine (C‐C motif) receptor 2 biases α1B‐adrenoceptor signaling: Implications for vascular funct	16
The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity	16
STAT3 transcriptionally regulates the expression of genes related to glycogen metabolism in developing motor neurons	16
Does the nuclear envelope retain its identity during mitosis?	16
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A highly active S1‐P1 nuclease from the opportunistic pathogen Stenotrophomonas maltophilia cleaves c‐di‐GMP	16
Structural basis for substrate and antibiotic recognition by Helicobacter pylori isoleucyl‐tRNA synthetase	16
Front Cover	16
Membrane occupation and recognition nexus (MORN) motif controls protein localization and function	15
SARS‐CoV‐2‐derived protein Orf9b enhances MARK2 activity via interaction with the autoinhibitory KA1 domain	15
Coordinating nucleoporin condensation and nuclear pore complex assembly	15
The S‐adenosylmethionine analog sinefungin inhibits the trimethylguanosine synthase TGS1 to promote telomerase activity and telomere lengthening	15
Neuronostatin regulates proliferation and differentiation of rat brown primary preadipocytes	15
THAP3 recruits SMYD3 to OXPHOS genes and epigenetically promotes mitochondrial respiration in hepatocellular carcinoma	15
The role of Lin28A and Lin28B in cancer beyond Let‐7	15
Characterizing the amino acid activation center of the naturally editing‐deficient aminoacyl‐tRNA synthetase PheRS in Mycoplasma mobile	15
It's a two‐way street: Photoswitching and reversible changes of the protein matrix in photoswitchable fluorescent proteins and bacteriophytochromes	15
Molecular determinants of lipid droplet subpopulations and their fates	15
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MiR‐15b‐5p inhibits castration‐resistant growth of prostate cancer cells by targeting the muscarinic cholinergic receptor CHRM3	14
Transcription‐coupled DNA repair protects genome stability upon oxidative stress‐derived DNA strand breaks	14
Glutamate dehydrogenase enables Salmonella to survive under oxidative stress and escape from clearance in macrophages	14
The enigmatic world of tear extracellular vesicles (EVs)–exploring their role in ocular health and beyond	14
The age‐related decline of helicase function—how G‐quadruplex structures promote genome instability	14
ATG and ESCRT control multiple modes of microautophagy	14
The Melolontha melolontha entomopoxvirus fusolin protein is a chitin‐active lytic polysaccharide monooxygenase that displays extreme stability	14
AKT controls NLRP3 inflammasome activation by inducing DDX3X phosphorylation	14
Front Cover	13
Front Cover	13
Acetylation stabilises calmodulin‐regulated calcium signalling	13
Senile plaques in Alzheimer's disease arise from Aβ‐ and Cathepsin D‐enriched mixtures leaking out during intravascular haemolysis and microaneurysm rupture	13
Middle East respiratory syndrome coronavirus ORF4b protein inhibits TLR7‐ and TLR9‐dependent alpha interferon induction	13
Endothelial lipase‐binding peptides similar to netrin‐1 inhibit hepatitis B virus infection	13
Front Cover	13
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Front Cover	13
Predicting genome‐wide tissue‐specific enhancers via combinatorial transcription factor genomic occupancy analysis	12
The 3D‐structure, kinetics and dynamics of the E. coli nitroreductase NfsA with NADP+ provide glimpses of its catalytic mechanism	12
Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury	12
Crystal structure of a novel heterooligomeric aminotransferase from Serratia sp. ATCC 39006 provides insights into function	12
Abiogenesis through gradual evolution of autocatalysis into template‐based replication	12
Tumour suppressor p53 inhibits hepatitis C virus replication by inducing E6AP‐mediated proteasomal degradation of the viral core protein	12
GENIGMA: an app to map the 3D genome of cancer cell lines through extreme citizen science	12
Deacylases—structure, function, and relationship to diseases	12
Aggregation and mobility of membrane proteins interplay with local lipid order in the plasma membrane of T cells	12
Retraction Statement: miR‐188 promotes senescence of lineage‐negative bone marrow cells by targeting MAP3K3 expression	11
Bioinspired and biomolecular catalysts for energy conversion and storage	11
Lipid droplets and fatty acid‐induced lipotoxicity: in a nutshell	11
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The orf virus (ORFV) protein OV20.0 interacts with the microprocessor complex subunit DGCR8 to regulate miRNA biogenesis and ORFV infection	11
Targeting RNA‐binding proteins with small molecules: Perspectives, pitfalls and bifunctional molecules	11
Photosystems and photoreceptors in cyanobacterial phototaxis and photophobotaxis	11
GCN2 kinase‐mediated upregulation of ubiquitin C maintains intracellular glutamine level and tRNAGln(CUG) charging under amino acid starvation	11
The roles of molecular chaperones in regulating cell metabolism	11
Retraction statement: MicroRNA‐520g induces epithelial‐mesenchymal transition and promotes metastasis of hepatocellular carcinoma by targeting SMAD7	11
Front Cover	11
From the sideline: Tissue‐specific nucleoporin function in health and disease, an update	11
Engineering ergothioneine production in Yarrowia lipolytica	11
Unorthodox regulation of the MglA Ras‐like GTPase controlling polarity in Myxococcus xanthus	11
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Krüppel‐like factor 6 participates in extravillous trophoblast cell differentiation and its expression is reduced in abnormally invasive placenta	11
Front Cover	10
Sticholysin I–II oligomerization in the absence of membranes	10
Autophagy as a caretaker of nuclear integrity	10
The clinically relevant triple mutation in the mtND1 gene inactivates Escherichia coli complex I	10
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum	10
Endocytic proteins mediating GPR15 receptor internalization provide insight into the underlying mechanisms	10
GABARAP interacts with EGFR — supporting the unique role of this hAtg8 protein during receptor trafficking	10
Molecular characterization of a moss isoprene synthase provides insight into its evolution	10
Structural and functional insights into the enzymatic activities of lipases from Burkholderia stagnalis and Burkholderia plantarii	10
Lipocalin 2 inhibits actin glutathionylation to promote invasion and migration	10
Release of FUS into the extracellular space is regulated by its amino‐terminal prion‐like domain	10
Integrin β1 transduces the signal for LY6D‐induced macropinocytosis and mediates senescence‐inducing stress‐evoked vacuole formation via FAK	10
Hypoxanthine‐guanine phosphoribosyltransferase is activated via positive cooperativity between guanine and IMP	10
STAP‐2 negatively regulates BCR‐mediated B cell activation by recruiting tyrosine‐protein kinase CSK to LYN	10
The survival grip–how cell adhesion promotes tumor maintenance within the microenvironment	10
Temperature adaptation of yeast phospholipid molecular species at the acyl chain positional level	10
Yeast Sec14‐like lipid transfer proteins Pdr16 and Pdr17 bind and transfer the ergosterol precursor lanosterol in addition to phosphatidylinositol	10

Cis‐regulatory evolution underlying the changes in wingless expression pattern associated with wing pigmentation of Drosophila	10
Odz4 upregulates SAN‐specific genes to promote differentiation into cardiac pacemaker‐like cells	10
Autophagy in a Nutshell	9
Human WIPI β‐propeller function in autophagy and neurodegeneration	9
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Clinically observed deletions in SARS‐CoV‐2 Nsp1 affect its stability and ability to inhibit translation	9
Mitochondrial permeability transition mediated by MTCH2 and F‐ATP synthase contributes to ferroptosis defense	9
Front Cover	9
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Mobile zinc as a modulator of sensory perception	9
A nanoemulsified formulation of dolutegravir and epigallocatechin gallate inhibits HIV‐1 replication in cellular models	9
The prolyl hydroxylase OGFOD1 promotes cancer cell proliferation by regulating the expression of cell cycle regulators	9
Deletion of the transcription factors Hsf1, Msn2 and Msn4 in yeast uncovers transcriptional reprogramming in response to proteotoxic stress	9
Thiol redox switches regulate the oligomeric state of cyanobacterial Rre1, RpaA and RpaB response regulators	9
A new approach to making scientific research more efficient – rethinking sustainability	9
Charged sequence motifs increase the propensity towards liquid–liquid phase separation	9
The mechanics of the heart: zooming in on hypertrophic cardiomyopathy and cMyBP‐C	9
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Front Cover	9
F‐actin determines the time‐dependent shift in docking dynamics of glucagon‐like peptide‐1 granules upon stimulation of secretion	9
The chromatin repressors EZH2 and Suv4‐20h coregulate cell fate specification during hippocampal development	8
Overactivation of the androgen receptor exacerbates gravid uterine ferroptosis via interaction with and suppression of the NRF2 defense signaling pathway	8
Structural determinants for membrane binding of the EGFR juxtamembrane domain	8
Nucleocytoplasmic transport at the crossroads of proteostasis, neurodegeneration and neuroprotection	8
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Nuclear pore complex and nucleocytoplasmic transport disruption in neurodegeneration	8
Liver gene transfer for metabolite detoxification in inherited metabolic diseases	8
Arabidopsis mutants lacking DLDG1 and non‐photochemical quenching‐related proteins reveal the regulatory role of DLDG1 in chloroplast pH homeostasis	8
Front Cover	8
Clues to transcription/replication collision‐induced DNA damage: it was RNAP, in the chromosome, with the fork	8
Evidence for partial functional overlap of KEA and MSL transport proteins in the chloroplast inner envelope of Arabidopsis thaliana	8
The deubiquitinase USP10 mediates crosstalk between the LKB1/AMPK axis and Wnt/β‐catenin signaling in cancer	8
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Distinct classes of misfolded proteins differentially affect the growth of yeast compromised for proteasome function	8
The winner of the 2024 FEBS Letters Award—an interview with Rachel Flynn	8
The dual nature of TDC – bridging dendritic and T cells in immunity	8
Ablation of fatty acid desaturase 2 (FADS2) exacerbates hepatic triacylglycerol and cholesterol accumulation in polyunsaturated fatty acid‐depleted mice	8
Succinate oxidation rescues mitochondrial ATP synthesis at high temperature in Drosophila melanogaster	8
EZH2 modulates retinoic acid signaling to ensure myotube formation during development	8
Brain lipidomic profiles of sleep enhancement through co‐administration of alprazolam and CGS21680	7
Transcription as a double‐edged sword in genome maintenance	7
ABC transporter activity is affected by the size of lipid nanodiscs	7
A γ‐glutamyl hydrolase lacking the signal peptide confers susceptibility to folates/antifolates in acute lymphoblastic leukemia cells	7
BRET analysis reveals interaction between the lysophosphatidic acid receptor LPA2 and the lysophosphatidylinositol receptor GPR55 in live cells	7
Dissecting the Ca2+ dependence of DesA1 function in Mycobacterium tuberculosis	7
Knockout of the BRAP homolog in mice leads to abnormal tracheal cilia	7
Conjugative transfer of the IncN plasmid pKM101 is mediated by dynamic interactions between the TraK accessory factor and TraI	7
Hidden biochemical fossils reveal an evolutionary trajectory for glycolysis in the prebiotic era	7
Strigolactone biosynthesis in rice can occur via a 9‐cis‐3‐OH‐10′‐apo‐β‐carotenal intermediate	7
Decline of ergothioneine in frailty and cognition impairment	7
The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation	7
Blueprints for the scientific society of the future: how FEBS and other scientific societies will have changed 60 years from now	7
The FEBS 60th anniversary writing contest—blueprints for the scientific society of tomorrow	7
HNF4α overexpression enhances the therapeutic potential of umbilical cord mesenchymal stem/stromal cells in mice with acute liver failure	7
hnRNPA1 enhances FOXP3 stability to promote the differentiation and functions of regulatory T cells	7
Activation of the purinergic receptor P2X7 improves hepatosteatosis by promoting lipophagy	7
Does Lactobacillus reuteri influence ergothioneine levels in the human body?	7
Comparative characterization of nine novel GH51, GH54 and GH62 α‐l‐arabinofuranosidases from Penicillium subrubescens	7
RETRACTION: Theaflavins Retard Human Breast Cancer Cell Migration by Inhibiting NF‐κB via p53‐ROS Cross‐talk	7
A weak COPI binding motif in the cytoplasmic tail of SARS‐CoV‐2 spike glycoprotein is necessary for its cleavage, glycosylation, and localization	7
The structure of a Lactobacillus helveticus chlorogenic acid esterase and the dynamics of its insertion domain provide insights into substrate binding	7
Front Cover	7
The radical impact of oxygen on prokaryotic evolution—enzyme inhibition first, uninhibited essential biosyntheses second, aerobic respiration third	7
Quinone chemistry in respiratory complex I involves protonation of a conserved aspartic acid residue	7
Corrigendum	7
The scorpion toxin BeKm‐1 blocks hERG cardiac potassium channels using an indispensable arginine residue	7
Two phosphoenolpyruvate carboxykinases with differing biochemical properties in Chlamydomonas reinhardtii	7
You are who your friends are—nuclear pore proteins as components of chromatin‐binding complexes	7
Single‐dose immunisation with a multimerised SARS‐CoV‐2 receptor binding domain (RBD) induces an enhanced and protective response in mice	7
LIM protein Ajuba promotes liver cell proliferation through its involvement in DNA replication and DNA damage control	7
Front Cover	7
Urinary microRNA profiling in pregnant women identifies placental microRNAs that are candidate biomarkers for monitoring placental health	7
Front Cover	7
Front Cover	7
Binding and/or hydrolysis of purine‐based nucleotides is not required for IM30 ring formation	7
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Structure and stability of phycocyanin from thermotolerant Oscillatoria	6
Age‐associated myeloid malignancies – the role of STAT3 and STAT5 in myelodysplastic syndrome and acute myeloid leukemia	6
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The activator/repressor Hap1 binds to the yeast eIF5A‐encoding gene TIF51A to adapt its expression to the mitochondrial functional status	6
TUBA1A licenses APC/C‐mediated mitotic progression to drive glioblastoma growth by inhibiting PLK3	6
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Human‐biased TMEM25 expression promotes expansion of neural progenitor cells to alter cortical structure in the developing brain	6
A guide for blood–brain barrier models	6
Spontaneous and chaperone‐assisted metal loading in the active site of protein phosphatase‐1	6
Deubiquitinases at the interplay between hematopoietic stem cell aging and myelodysplastic transformation	6
Comparative structural analysis provides new insights into the function of R2‐like ligand‐binding oxidase	6
Front Cover	6
Bebtelovimab‐bound SARS‐CoV‐2 RBD mutants: resistance profiling and validation with escape mutations, clinical results, and viral genome sequences	6
Human PHOSPHO1 exhibits phosphatidylcholine‐ and phosphatidylethanolamine‐phospholipase C activities and interacts with diacylglycerol kinase δ	6
Endomembrane‐mediated storage protein trafficking in plants: Golgi‐dependent or Golgi‐independent?	6
l‐2‐Aminopimelic acid acts as an auxin mimic to induce lateral root formation across diverse plant species	6
Poliovirus capsid protein VP3 can penetrate vascular endothelial cells	6
Structural analyses of the AAA+ ATPase domain of the transcriptional regulator GtrR in the BDSF quorum‐sensing system in Burkholderia cenocepacia	6
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