FEBS Letters

Papers
(The median citation count of FEBS Letters is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)
ArticleCitations
Front Cover68
Front Cover68
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Microscopic modulation and analysis of islets of Langerhans in living zebrafish larvae56
Mechanisms and kinetic assays of aminoacyl‐ tRNA synthetases47
The inhibitory SAPS3AMPK interaction detected in HEK293 47
CRK and NCK adaptors may functionally overlap in zebrafish neurodevelopment, as indicated by common binding partners and overlapping expression patterns46
Mycobacterium tuberculosis low molecular weight T‐cell antigen Mtb8.4 has heme‐binding and fiber‐forming properties43
Insight into the function of the Golgi membrane protein GOLM1 in cholangiocytes through interactomic analysis41
Molecular and mechanical mechanisms of animal cell abscission41
Artificial miRNAs derived from miR‐181 family members have potential in cancer therapy due to an altered spectrum of target mRNAs41
Clinical and mechanistic insights into the roles of DDX41 in haematological malignancies40
A two‐step mechanism for the binding of the HIV‐1 MPER epitope by the 10E8 antibody onto biosensor‐supported lipid bilayers40
Cytochrome bd‐I from Escherichia coli is catalytically active in the absence of the CydH subunit40
Mice deficient in the phosphatase activity of sEH show decreased levels of the endocannabinoid 2‐ AG 39
ArabidopsisRAN GTPases are critical for mitosis during male and female gametogenesis39
The bacterial MRE11RAD50 and DNA238
Cordycepin generally inhibits growth factor signal transduction in a systems pharmacology study38
Purification tags markedly affect self‐aggregation of CPEB338
Deubiquitinase USP2 promotes hepatic stellate cell activation via p300 stabilization36
The crystal structure of the TPR domain of the EccA5 ATPase and demonstration of its interaction w36
CPEB3 selectively inhibits α‐synuclein aggregation without modulating TDP ‐43 pathology36
The ubiquitin–proteasome system and autophagy mutually interact in neurotoxin‐induced dopaminergic cell death models of Parkinson's disease35
Heparin promotes rapid fibrillation of the basic parathyroid hormone at physiological pH34
Skraban‐Deardorff intellectual disability syndrome‐associated mutations in WDR 26 impair CTLH E 3 34
Silica‐coated magnetic nanobeads in a flow enrichment target capture Halbach ( FETCH ) magnetic separation system for circulating tumor cell enrichme34
Novel insights into autophagosome biogenesis revealed by cryo‐electron tomography33
The fatty acid synthase inhibitor C75 differentially affects the adipogenic differentiation of multipotent cells and preadipocytes32
miR‐4734 conditionally suppresses ER stress‐associated proinflammatory responses31
Reciprocal control of viral infection and phosphoinositide dynamics31
Mapping secondary substrate‐binding sites on the GH11 xylanase from Bacillus subtilis30
Spatial regulation of ARL3 and GSF ‐mediated lipidated cargo trafficking in the primary cilium30
Front Cover29
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Homocysteine thiolactone and H2O2 induce amino acid modifications and alter the fibrillation propensity of the Aβ25–35 peptide27
Cell culture pioneer Jaroslav Cinatl—the pursuit and defence of truth27
PAT m RNA decapping factors are required for proper development in Arabidopsis27
Insights into PI3K / AKT signaling in B cell development and chronic lymphocytic leukemia26
A novel approach to single‐cell analysis reveals intrinsic differences in immune marker expression in unstimulated BALB/c and C57BL/6 macrophages26
Structural and functional insights of itaconyl‐CoA hydratase from Pseudomonas aeruginosa highlight a novel N‐terminal hotdog fold26
Cas9‐Geminin and Cdt1‐fused anti‐CRISPR protein synergistically increase editing accuracy26
Generation of novel anti‐apo E monoclonal antibodies that selectively recognize apo E isoforms25
Autophagy in the regulation of cancer dormancy25
A working model for cytoplasmic assembly of H/ ACA snoRNPs25
Human phytanoyl‐CoA dioxygenase domain‐containing 1 (PHYHD1) is a putative oxygen sensor associated with RNA and carbohydrate metabolism25
Retraction statement: miR ‐518b is down‐regulated, and involved in cell proliferation and invasion by targeting Rap1b in esophageal squamous cell car25
Intron‐oriented HTLV ‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 23
MyD88 and not TRIF knockout is sufficient to abolish LPS‐induced inflammatory responses in bone‐derived macrophages23
Unlocking the biochemical secrets of longevity: balancing healthspan and lifespan23
Fluorescence‐based CRISPR interference system for controlled genetic repression and live single‐cell imaging in mycobacteria23
Elucidation of interface interactions between a dehydratase domain and an acyl carrier protein in cremimycin polyketide synthase23
Siderophore specificities of the Pseudomonas aeruginosa TonB‐dependent transporters ChtA and ActA23
Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy22
Exploring the potential of AlphaFold distograms for predicting binding‐induced hinge motions22
Solving the protein folding problem…21
Protein disulfide isomerase dissolves and detoxifies oligomeric assemblies of amyloid beta peptide21
Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions21
RANBP2 evolution and human disease21
Does the nuclear envelope retain its identity during mitosis?20
Neuronostatin regulates proliferation and differentiation of rat brown primary preadipocytes19
The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases19
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The age‐related decline of helicase function—how G‐quadruplex structures promote genome instability19
Structural basis for substrate and antibiotic recognition by Helicobacter pylori isoleucyl‐t RNA synth19
The BcsD subunit of type I bacterial cellulose synthase interacts dynamically with the BcsAB catalytic core complex19
Front Cover19
Transcription‐coupled DNA repair protects genome stability upon oxidative stress‐derived DNA stran19
The enigmatic world of tear extracellular vesicles (EVs)–exploring their role in ocular health and beyond19
Fanzors, a family of eukaryotic RNA‐guided DNA endonucleases19
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STAT3 transcriptionally regulates the expression of genes related to glycogen metabolism in developing motor neurons18
Heteromerization between α1B‐adrenoceptor and chemokine (C‐C motif) receptor 2 biases α1B‐adrenoceptor signaling: Implications for vascular funct18
The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity18
Small GTPase signaling hubs at the surface of cellular membranes in physiology and disease18
Molecular determinants of lipid droplet subpopulations and their fates18
Coordinating nucleoporin condensation and nuclear pore complex assembly18
Membrane occupation and recognition nexus (MORN) motif controls protein localization and function18
Kit structural mutations associated with the porcine dominant white phenotype impair hematopoiesis in mice18
A novel perspective on the role of nucleus accumbens neurons in encoding associative learning17
It's a two‐way street: Photoswitching and reversible changes of the protein matrix in photoswitchable fluorescent proteins and bacteriophytochromes17
Gly56 in the synthetic site of isoleucyl‐tRNA synthetase confers specificity and maintains communication with the editing site17
THAP 3 recruits SMYD 3 to OXPHOS genes and epigenetically promotes 17
The Melolontha melolontha entomopoxvirus fusolin protein is a chitin‐active lytic polysaccharide monooxygenase that displays extreme stability17
A highly active S1‐P1 nuclease from the opportunistic pathogen Stenotrophomonas maltophilia cleaves c‐di‐GMP17
Social context prevents heat hormetic effects against mutagens during fish development16
Distinct dysregulated pathways in sporadic and Lynch syndrome‐associated colorectal cancer offer insights for targeted treatment16
Ischemic heart disease‐associated ∆ M1Q91 PDE5A2 mutant shows reduced efficacy for 16
Disrupting the interaction between a p53 gain‐of‐function mutant and the transcriptional co‐activator PC4 reverses drug resistance in cancer cells16
Diversity and complexity in neural organoids16
SARSC o V ‐2‐derived protein Orf9b enhances 16
A scorpion toxin affecting sodium channels shows double cistrans isomerism16
Structural differences in the outer membrane‐associated flagellar rings between sheathed and unsheathed flagella16
Membranes that make fat: roles of membrane lipids as acyl donors for triglyceride synthesis and organelle function16
The cytochrome oxidase defect in ISC ‐depleted yeast is caused by impaired iron–sulfur cluster maturation of the mitoribosome assembly factor Rsm2216
The role of Lin28A and Lin28B in cancer beyond Let‐716
Plasmodium falciparum ring‐infected erythrocyte surface antigen 3 ( PfRESA3 ) is a cytoskeleton‐interacting protein and po16
Front Cover15
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Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells15
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Front Cover15
Endothelial lipase‐binding peptides similar to netrin‐1 inhibit hepatitis B virus infection15
Front Cover15
Targeting RNA‐binding proteins with small molecules: Perspectives, pitfalls and bifunctional molecules15
Front Cover15
Front Cover15
Middle East respiratory syndrome coronavirus ORF4b protein inhibits TLR7‐ and TLR9‐dependent alpha interferon induction15
Bioinspired and biomolecular catalysts for energy conversion and storage15
Retraction Statement: miR‐188 promotes senescence of lineage‐negative bone marrow cells by targeting MAP3K3 expression14
The 3D‐structure, kinetics and dynamics of the E. coli nitroreductase NfsA with NADP+ provide glimpses of its catalytic mechanism14
Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury14
Senile plaques in Alzheimer's disease arise from Aβ‐ and Cathepsin D‐enriched mixtures leaking out during intravascular haemolysis and microaneurysm rupture14
MiR‐15b‐5p inhibits castration‐resistant growth of prostate cancer cells by targeting the muscarinic cholinergic receptor CHRM314
ATG and ESCRT control multiple modes of microautophagy14
Crystal structure of a novel heterooligomeric aminotransferase from Serratia sp. ATCC 39006 provides i14
Unorthodox regulation of the MglA Ras‐like GTPase controlling polarity in Myxococcus xanthus14
Tumour suppressor p53 inhibits hepatitis C virus replication by inducing E6AP‐mediated proteasomal degradation of the viral core protein14
The THO complex in Schizosaccharomyces pombe —dissecting the composition and functional hierarchy14
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 114
A coiled‐coil domain triggers oligomerization of MmpL10 , the mycobacterial transporter of trehalose polyphleate precursor13
From the sideline: Tissue‐specific nucleoporin function in health and disease, an update13
Lipid droplets and fatty acid‐induced lipotoxicity: in a nutshell13
Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl113
Photosystems and photoreceptors in cyanobacterial phototaxis and photophobotaxis13
Valosin‐containing protein counteracts ATP ‐driven dissolution of FUS condensates through its 13
Abiogenesis through gradual evolution of autocatalysis into template‐based replication13
Interferon‐induced protein ISG15 in the central nervous system, quo vadis?13
EGTA ‐induced disruption of adherens junctions in zebrafish embryonic epidermis13
GCN2 kinase‐mediated upregulation of ubiquitin C maintains intracellular glutamine level and tRNAGln(CUG) charging under amino acid starvation13
The roles of molecular chaperones in regulating cell metabolism13
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Predicting genome‐wide tissue‐specific enhancers via combinatorial transcription factor genomic occupancy analysis13
Deacylases—structure, function, and relationship to diseases12
Endocytic proteins mediating GPR15 receptor internalization provide insight into the underlying mechanisms12
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Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification12
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Structural and functional insights into the enzymatic activities of lipases from Burkholderia stagnalis and Burkholderia plantarii12
STAP ‐2 negatively regulates BCR ‐mediated B cell activation by recruiting tyrosine‐protein kinase 12
GABARAP interacts with EGFR — supporting the unique role of this hAtg8 protein during receptor trafficking12
Odz4 upregulates SAN ‐specific genes to promote differentiation into cardiac pacemaker‐like cells12
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum12
A nanoemulsified formulation of dolutegravir and epigallocatechin gallate inhibits HIV‐1 replication in cellular models12
Cis ‐regulatory evolution underlying the changes in wingless expression pattern associated with wing pigmentation of 12
Amy and Friends: improving the lives of individuals affected by DNA repair disorders11
Front Cover11
Mobile zinc as a modulator of sensory perception11
Advances in the development of organoid‐based models of the trachea and esophagus11
Autophagy in cancer and protein conformational disorders11
Molecular characterization of a moss isoprene synthase provides insight into its evolution11
Autophagy in a Nutshell11
Human WIPI β‐propeller function in autophagy and neurodegeneration11
Structural biology of ferritin nanocages11
Autophagy as a caretaker of nuclear integrity11
The Mycobacterium tuberculosis ESAT ‐6 protein inhibits differentiation of human monocytes to dendritic cells11
Krüppel‐like factor 6 participates in extravillous trophoblast cell differentiation and its expression is reduced in abnormally invasive placenta11
Lipocalin 2 inhibits actin glutathionylation to promote invasion and migration11
Integrin β1 transduces the signal for LY6D‐induced macropinocytosis and mediates senescence‐inducing stress‐evoked vacuole formation via FAK11
Yeast Sec14‐like lipid transfer proteins Pdr16 and Pdr17 bind and transfer the ergosterol precursor lanosterol in addition to phosphatidylinositol11
Temperature adaptation of yeast phospholipid molecular species at the acyl chain positional level11
The survival grip–how cell adhesion promotes tumor maintenance within the microenvironment11
Release of FUS into the extracellular space is regulated by its amino‐terminal prion‐like domain11
Clues to transcription/replication collision‐induced DNA damage: it was RNAP , in the chromosome, 10
The winner of the 2024 FEBS Letters Award—an interview with Rachel Flynn10
Front Cover10
Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides10
Front Cover10
Succinate oxidation rescues mitochondrial ATP synthesis at high temperature in Drosophila melanogaster10
A new approach to making scientific research more efficient – rethinking sustainability10
Mitochondrial permeability transition mediated by MTCH2 and F‐ ATP synthase contributes to ferropt10
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EXPRESSION OF CONCERN : Introgression of a Novel Salt‐Tolerant L‐ Myo ‐Inositol 1‐Phosphate Synthase from 10
Structural determinants for membrane binding of the EGFR juxtamembrane domain10
Evidence for partial functional overlap of KEA and MSL transport proteins in the chloroplast inner10
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Front Cover10
F‐actin determines the time‐dependent shift in docking dynamics of glucagon‐like peptide‐1 granules upon stimulation of secretion10
The dual nature of TDC – bridging dendritic and T cells in immunity10
ABL drives phosphorylation of Semaphorin 6 A at conserved tyrosines necessary for zebrafish retinal maintenance10
Inhibition of mitochondrial NADH :ubiquinone oxidoreductase by spinning oscillating magnetic fields causes toxicity in cancer cells10
Deletion of the transcription factors Hsf1, Msn2 and Msn4 in yeast uncovers transcriptional reprogramming in response to proteotoxic stress10
Blueprints for the scientific society of the future: how FEBS and other scientific societies will have changed 60 years from now9
The deubiquitinase USP10 mediates crosstalk between the LKB1/AMPK axis and Wnt/β‐catenin signaling in cancer9
Nucleocytoplasmic transport at the crossroads of proteostasis, neurodegeneration and neuroprotection9
Function‐driven design of a surrogate interleukin‐2 receptor ligand9
Front Cover9
Front Cover9
Front Cover9
Conserved structural motifs in PAS , LOV , and CRY 9
The prolyl hydroxylase OGFOD1 promotes cancer cell proliferation by regulating the expression of cell cycle regulators9
The interaction of PD ‐1/ PDL1 and its inhib9
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The FEBS 60th anniversary writing contest—blueprints for the scientific society of tomorrow9
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization9
Diacylglycerol kinase ε depletion suppresses LPS ‐stimulated NFκB9
Mechanisms of parasite‐mediated disruption of brain vessels9
Nuclear pore complex and nucleocytoplasmic transport disruption in neurodegeneration9
Front Cover9
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Liver gene transfer for metabolite detoxification in inherited metabolic diseases8
Analytical methods and tools for studying inositol phosphates8
C9orf72 ALS ‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules8
Hidden biochemical fossils reveal an evolutionary trajectory for glycolysis in the prebiotic era8
LIM protein Ajuba promotes liver cell proliferation through its involvement in DNA replication and DNA damage control8
The scorpion toxin BeKm‐1 blocks hERG cardiac potassium channels using an indispensable arginine residue8
Two phosphoenolpyruvate carboxykinases with differing biochemical properties in Chlamydomonas reinhardtii8
You are who your friends are—nuclear pore proteins as components of chromatin‐binding complexes8
Characterization of molecular mechanisms of CaMKKα/1 oligomerization8
RETRACTION : Theaflavins Retard Human Breast Cancer Cell Migration by Inhibiting NF‐κB via p53‐ROS Cross‐talk8
Conjugative transfer of the I nc N plasmid p KM 8
Quinone chemistry in respiratory complex I involves protonation of a conserved aspartic acid residue8
The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation8
Dissecting the Ca 2+ dependence of DesA1 function in Mycobacterium tuberculosis8
Inhibiting stearoyl‐ CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR 8
Motif‐guided trafficking of leishmanial PAS domain‐containing phosphoglycerate kinase into glycosomes and lysosomes8
HNF4α overexpression enhances the therapeutic potential of umbilical cord mesenchymal stem/stromal cells in mice with acute liver failure8
Knockout of the BRAP homolog in mice leads to abnormal tracheal cilia8
Urinary microRNA profiling in pregnant women identifies placental microRNAs that are candidate biomarkers for monitoring placental health8
Binding mechanism of adenylate kinase‐specific monobodies8
Brain lipidomic profiles of sleep enhancement through co‐administration of alprazolam and CGS216808
Arabidopsis mutants lacking DLDG1 and non‐photochemical quenching‐related proteins reveal the regulatory role of DLDG1 in chloroplast pH homeostasis8
The radical impact of oxygen on prokaryotic evolution—enzyme inhibition first, uninhibited essential biosyntheses second, aerobic respiration third8
Divergent effects of cholesterol on the structure and fluidity of liposome and catanionic vesicle membranes8
The acyl‐CoA‐binding protein Acb1 regulates mitochondria, lipid droplets, and cell proliferation7
RETRACTION : Role of the PDK1PKBGSK37
Exogenous fatty acids inhibit fatty acid synthesis by competing with endogenously generated substrates for phospholipid synthesis in Escherichia coli7
Development of visible light‐sensitive human neuropsin ( OPN5 ) via single amino acid substitution7
Poliovirus capsid protein VP3 can penetrate vascular endothelial cells7
Interactions of Escherichia coli SMC ‐like RecN protein with different 7
The activator/repressor Hap1 binds to the yeast eIF5A‐encoding gene TIF51A to adapt its expression to the mitochondrial functional status7
'The world needs science, and science needs women'…but what do women in science need? – interviews and panel discussion with 5 outstanding female scientists7
Reducing plastic waste in scientific protocols by 65% — practical steps for sustainable research7
Adding hydrophobicity or positive charges to the cytosolic half of the α‐synuclein 3–11 helix increases membrane association and S129 phosphorylation7
Structural basis for the minimal bifunctional alginate epimerase AlgE3 from Azotobacter chroococcum7
Front Cover7
Endomembrane‐mediated storage protein trafficking in plants: Golgi‐dependent or Golgi‐independent?7
Structural basis of a GatC ortholog transporter in the bacterial phosphotransferase system7
Circulating histones as clinical biomarkers in critically ill conditions7
TNFR2 signaling promotes monocytic‐ MDSC differentiation and production of immunosuppressive mediators7
A life‐time of hematopoietic cell function: ascent, stability, and decline7
Spontaneous and chaperone‐assisted metal loading in the active site of protein phosphatase‐17
Small RNA sequencing in hypoxic naked mole‐rat hearts suggests microRNA regulation of RNA‐ and translation‐related processes7
Deubiquitinases at the interplay between hematopoietic stem cell aging and myelodysplastic transformation7
Structure and stability of phycocyanin from thermotolerant Oscillatoria7
Age‐associated myeloid malignancies – the role of STAT3 and STAT5 in myelodysplastic syndrome and 7
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