Experimental and Molecular Pathology

Article	Citations
Neuro-protective roles of long non-coding RNA MALAT1 in Alzheimer's disease with the involvement of the microRNA-30b/CNR1 network and the following PI3K/AKT activation	53
LEPR hypomethylation is significantly associated with gastric cancer in males	52
Targeting miR-10a-5p/IL-6R axis for reducing IL-6-induced cartilage cell ferroptosis	48
Type I astrocytes and microglia induce a cytokine response in an encephalitic murine coronavirus infection	40
Human umbilical cord mesenchymal stem cell-derived exosomes suppress dermal fibroblasts-myofibroblats transition via inhibiting the TGF-β1/Smad 2/3 signaling pathway	38
The role of activated leukocyte cell adhesion molecule (ALCAM) in cancer progression, invasion, metastasis and recurrence: A novel cancer stem cell marker and tumor-specific prognostic marker	36
The PI3K/AKT signaling pathway in cancer: Molecular mechanisms and possible therapeutic interventions	36
MicroRNA-199a-3p inhibits angiogenesis by targeting the VEGF/PI3K/AKT signalling pathway in an in vitro model of diabetic retinopathy	32
LncRNAs and miRNAs participate in determination of sensitivity of cancer cells to cisplatin	32
MiRNA-339-5p suppresses the malignant development of gastric cancer via targeting ALKBH1	30
miRNA signature in glioblastoma: Potential biomarkers and therapeutic targets	27
RETRACTED: Aberrant expression of lncRNA MALAT1 modulates radioresistance in colorectal cancer in vitro via miR-101-3p sponging	27
Long non-coding RNA muskelin 1 antisense RNA (MKLN1-AS) is a potential diagnostic and prognostic biomarker and therapeutic target for hepatocellular carcinoma	26
Expression analysis of vimentin and the related lncRNA network in breast cancer	26
The critical roles of lncRNAs in the pathogenesis of melanoma	25
MiR-302a-3p aggravates myocardial ischemia-reperfusion injury by suppressing mitophagy via targeting FOXO3	25
Dual role of heme iron in cancer; promotor of carcinogenesis and an inducer of tumour suppression	25
TGF-β1 signaling can worsen NAFLD with liver fibrosis backdrop	24
Therapeutic potential of mesenchymal stem cell-derived extracellular vesicles as novel cell-free therapy for treatment of autoimmune disorders	24
The PI3K-AKT pathway: A plausible therapeutic target in Parkinson's disease	23
LncRNA SNHG1 contributes to the cisplatin resistance and progression of NSCLC via miR-330-5p/DCLK1 axis	23
The role of genetic polymorphism within PD-L1 gene in cancer. Review	23
Cytokeratin 7 and cytokeratin 20 expression in cancer: A tissue microarray study on 15,424 cancers	22
LncRNA KCNQ1OT1 contributes to cardiomyocyte apoptosis by targeting FUS in heart failure	22
Dexmedetomidine protects intestinal ischemia-reperfusion injury via inhibiting p38 MAPK cascades	21

Circ_DCAF6 potentiates cell stemness and growth in breast cancer through GLI1-Hedgehog pathway	20
Circ-ITCH restrains the expression of MMP-2, MMP-9 and TNF-α in diabetic retinopathy by inhibiting miR-22	20
Long non-coding RNA HAGLROS regulates lipid metabolism reprogramming in intrahepatic cholangiocarcinoma via the mTOR signaling pathway	20
Circ_AFF2 facilitates proliferation and inflammatory response of fibroblast-like synoviocytes in rheumatoid arthritis via the miR-375/TAB2 axis	19
Astragaloside-IV regulates endoplasmic reticulum stress-mediated neuronal apoptosis in a murine model of Parkinson's disease via the lincRNA-p21/CHOP pathway	18
Enhanced expression of lncRNA ZXF1 promotes cisplatin resistance in lung cancer cell via MAPK axis	18
Mortalin promotes breast cancer malignancy	18
LncRNA PCGEM1 enhances metastasis and gastric cancer invasion through targeting of miR-129-5p to regulate P4HA2 expression	18
New insights into long non-coding RNAs in breast cancer: Biological functions and therapeutic prospects	17
Circ-XPO1 upregulates XPO1 expression by sponging multiple miRNAs to facilitate osteosarcoma cell progression	17
DYNLL1 is hypomethylated and upregulated in a tumor stage- and grade-dependent manner and associated with increased mortality in hepatocellular carcinoma	17
Regulatory effect of LncRNA DRAIC/miR-149-5p/NFIB molecular network on autophagy of esophageal cancer cells and its biological behavior	17
Effect of aberrant DNA methylation on cancer stem cell properties	17
Protective effect of dapsone against bleomycin-induced lung fibrosis in rat	16
Down-regulation of long noncoding RNA LINC00472 alleviates sepsis-induced acute hepatic injury by regulating miR-373-3p/TRIM8 axis	16
The cell theory and cellular pathology: Discovery, refinements and applications fundamental to advances in biology and medicine	16
MiR-195 suppression alleviates apoptosis and oxidative stress in CCl4-induced ALI in mice by targeting Pim-1	16
Roles of a TMPO-AS1/microRNA-200c/TMEFF2 ceRNA network in the malignant behaviors and 5-FU resistance of ovarian cancer cells	16
FOXM1-induced upregulation of lncRNA OR3A4 promotes the progression of diffuse large B-cell lymphoma via Wnt/β-catenin signaling pathway	16
microRNA-216a protects against human retinal microvascular endothelial cell injury in diabetic retinopathy by suppressing the NOS2/JAK/STAT axis	15
CircWHSC1 regulates malignancy and glycolysis by the miR-212-5p/AKT3 pathway in triple-negative breast cancer	15
miRNA microarray profiling in patients with androgenic alopecia and the effects of miR-133b on hair growth	14
Long non-coding RNA H19 in the liver-gut axis: A diagnostic marker and therapeutic target for liver diseases	14
Analysis on the expression and value of CCL2 and CCL3 in patients with osteoarthritis	13
Up-regulation of miRNA-151-3p enhanced the neuroprotective effect of dexmedetomidine against β-amyloid by targeting DAPK-1 and TP53	13
Sarcopenia, oxidative stress and inflammatory process in muscle of cirrhotic rats – Action of melatonin and physical exercise	12
Nitroglycerin ameliorates sperm parameters, oxidative stress and testicular injury following by testicular torsion/detorsion in male rats	12
Circ-E2F3 acts as a ceRNA for miR-204-5p to promote proliferation, metastasis and apoptosis inhibition in retinoblastoma by regulating ROCK1 expression	12
miR-188-5p inhibits apoptosis of neuronal cells during oxygen-glucose deprivation (OGD)-induced stroke by suppressing PTEN	12
A novel prognostic index of stomach adenocarcinoma based on immunogenomic landscape analysis and immunotherapy options	12
Long noncoding RNA LINC00978 acts as a potential diagnostic biomarker in patients with colorectal cancer	12
Role of RBM3 in the regulation of cell proliferation in hepatocellular carcinoma	12
Targeted next generation sequencing panel for HPV genotyping in cervical cancer	12
Prognostic and clinicopathological significance of TMEFF2, SMOC-2, and SOX17 expression in endometrial carcinoma	12
High prevalence of ROS1 gene rearrangement detected by FISH in EGFR and ALK negative lung adenocarcinoma	12
HBXIP accelerates glycolysis and promotes cancer angiogenesis via AKT/mTOR pathway in bladder cancer	11
The pleiotropic peroxisome proliferator activated receptors: Regulation and therapeutics	11
miR-200c increases the sensitivity of breast cancer cells to Doxorubicin through downregulating MDR1 gene	11
Novel Biocartis Idylla™ cartridge-based assay for detection of microsatellite instability in colorectal cancer tissues	11
MicroRNA-29a functions as a tumor suppressor through targeting STAT3 in laryngeal squamous cell carcinoma	11
PRR34-AS1 sponges miR-498 to facilitate TOMM20 and ITGA6 mediated tumor progression in HCC	11
Aluminum exposure promotes histopathological and pro-oxidant damage to the prostate and gonads of male and female adult gerbils	10
RETRACTED: The effect of LncRNA SNHG16 on vascular smooth muscle cells in CHD by targeting miRNA-218-5p	10
Standardization of diethylnitrosamine-induced hepatocellular carcinoma rat model with time based molecular assessment	10
MiR-93/HMGB3 regulatory axis exerts tumor suppressive effects in colorectal carcinoma cells	10
LINC00665 activates Wnt/β-catenin signaling pathway to facilitate tumor progression of colorectal cancer via upregulating CTNNB1	10
Effect of fibroblast growth factor 2 on degenerative endplate chondrocyte: From anabolism to catabolism	10
HOX transcript antisense RNA: An oncogenic lncRNA in diverse malignancies	10
Central nervous system (CNS) tumor cell heterogeneity contributes to differential platinum-based response in an in vitro 2D and 3D cell culture approach	10
Overexpression of CD200 and CD123 is a major influential factor in the clinical course of pediatric acute myeloid leukemia	10

Role of miRNAs in conveying message of stem cells via extracellular vesicles	10
RETRACTED: Low-expressed GAS5 injure myocardial cells and progression of chronic heart failure via regulation of miR-223-3P	10
Important role of annexin A2 (ANXA2) in new blood vessel development in vivo and human triple negative breast cancer (TNBC) growth	10
The regulatory role of SFRP5/WNT5A axis in allergic rhinitis through inhibiting JNK pathway activation and lowering mucin generation in human nasal epithelial cells	10
Tumour suppressor role of microRNA-335-5p in esophageal squamous cell carcinoma by targeting TTK (Mps1)	10
MiR-487a-3p suppresses the malignant development of pancreatic cancer by targeting SMAD7	9
Human primary chronic wound derived fibroblasts demonstrate differential pattern in expression of fibroblast specific markers, cell cycle arrest and reduced proliferation	9
Inhibition of miR-1224 suppresses hypoxia/reoxygenation-induced oxidative stress and apoptosis in cardiomyocytes through targeting GPX4	9
The coding microsatellite mutation profile of PMS2-deficient colorectal cancer	9
Clinical implementation of plasma EGFR T790M testing using droplet digital PCR in TKI-resistant NSCLC patients	9
Investigating the regulatory function of the ANO1-AS2 on the ANO1 gene in infertile men with asthenozoospermia and terato-asthenozoospermia	9
Ranolazine alleviated cardiac/brain dysfunction in doxorubicin-treated rats	9
Long noncoding RNA-GAS5 retards renal fibrosis through repressing miR-21 activity	9
Expression profiling revealed up-regulation of three lncRNAs in breast cancer samples.	9
miR-155 facilitates calcium oxalate crystal-induced HK-2 cell injury via targeting PI3K associated autophagy	9
Elevated circRNAs circ_0000745, circ_0001531 and circ_0001640 in human whole blood: Potential novel diagnostic biomarkers for breast cancer	9
Down-regulation of lncRNA PCGEM1 inhibits cervical carcinoma by modulating the miR-642a-5p/LGMN axis	9
DROSHA rs10719 and DICER1 rs3742330 polymorphisms in endometriosis and different diseases: Case-control and review studies.	9
The role of the peritoneal microenvironment in the pathogenesis of colorectal peritoneal carcinomatosis	9
SMAD7 and SMAD4 expression in colorectal cancer progression and therapy response	8
Sirt2 positively regulates muscle regeneration after Notexin-induced muscle injury	8
Antihyperglycemic activity of L-norvaline and L-arginine in high-fat diet and streptozotocin-treated male rats	8
Role of different Th17 and Treg downstream signalling pathways in the pathogenesis of Staphylococcus aureus infection induced septic arthritis in mice	8
SETD8 promotes stemness characteristics and is a potential prognostic biomarker of gastric adenocarcinoma	8
ESRG, LINC00518 and PWRN1 are newly-identified deregulated lncRNAs in colorectal cancer	8
Fragmentation assessment of FFPE DNA helps in evaluating NGS library complexity and interpretation of NGS results	8
Phloretin enhances autophagy by impairing AKT activation and inducing JNK-Beclin-1 pathway activation	8
Autophagy and immune microenvironment in craniopharyngioma and ameloblastoma	7
Nucleotide-binding oligomerization domain protein 1 enhances oxygen-glucose deprivation and reperfusion injury in cortical neurons via activation of endoplasmic reticulum stress-mediated autophagy	7
Critical roles of microRNA-196 in normal physiology and non-malignant diseases: Diagnostic and therapeutic implications	7
Remote ischemic postconditioning attenuates damage in rats with chronic cerebral ischemia by upregulating the autophagolysosome pathway via the activation of TFEB	7
The role of cell surface proteins gene expression in diagnosis, prognosis, and drug resistance of colorectal cancer: In silico analysis and validation	7
A review of the critical role of vitamin D axis on the immune system	7
Effects of miR-599 targeting YAP1 on proliferation, invasion and apoptosis of bladder urothelial carcinoma cells	7
Characterization of the rabbit conjunctiva: Effects of sulfur mustard	7
Dysregulation of non-coding RNAs in autoimmune thyroid disease	7
Lung metastases and subsequent malignant transformation of a fumarate hydratase -deficient uterine leiomyoma	6
Pimitespib is effective on cecal GIST in a mouse model of familial GISTs with KIT-Asp820Tyr mutation through KIT signaling inhibition	6
Targeted-regulating of miR-515-5p by LncRNA LOXL1-AS1 on the proliferation and migration of trophoblast cells	6
HOXB2 and FOXC1 synergistically drive the progression of Wilms tumor	6
Prognostic value of tumor stromal collagen features in patients with hepatocellular carcinoma revealed by second-harmonic generation microscopy	6
LncRNA RHPN1-AS1 promotes the progression of nasopharyngeal carcinoma by targeting CELF2 expression	6
Nodular fasciitis of the breast: Report of two cases illustrating the diagnostic implications for USP6 gene rearrangement and brief review of the literature	6
The biogenesis, biological functions and modification of Circular RNAs	6
Downregulation of MicroRNA-494 inhibits the TGF-β1/Smads signaling pathway and prevents the development of hypospadias through upregulating Nedd4L	6
Comparison of Biocartis IDYLLA ™ cartridge assay with Qiagen GeneReader NGS for detection of targetable mutations in EGFR, KRAS/NRAS, and BRAF genes	6
Neuregulin 1/ErbB4/Akt signaling attenuates cytotoxicity mediated by the APP-CT31 fragment of amyloid precursor protein	6
RETRACTED: Loss of microRNA-30e induced by extracellular vesicles from cancer-associated fibroblasts promotes breast cancer progression by binding to CTHRC1	6
Functional roles of exosomal miRNAs in multi-drug resistance in cancer chemotherapeutics	6
Integrated analysis of multiple microarray studies to identify potential pathogenic gene modules in preeclampsia	6
Long non-coding RNA Hsp4 alleviates lipopolysaccharide-induced apoptosis of lung epithelial cells via miRNA-466m-3p/DNAjb6 axis	6
Antiandrogen abiraterone and docetaxel treatments affect Notch1, Jagged1 and Hes1 expressions in metastatic prostate cancer cells	6
DICER-AS1 lncRNA: A putative culprit in the pathogenesis of gastric cancer	6
HSPB8 promoted intrahepatic cholangiocarcinoma progression by enhancing epithelial-mesenchymal transition and autophagy	6
Expression of activator proteins of SHH/GLI and PI3K/Akt/mTORC1 signaling pathways in human gliomas is associated with high grade tumors	6
Expression and change of miR-199b-5p, s HLA-G in thyroid carcinoma	6
ADAM7 promotes the proliferation and invasion in trophoblast cells	5
miR-876-3p suppresses the progression of colon cancer and correlates the prognosis of patients	5
Exosomes isolated from the miR-215-modified bone marrow mesenchymal stem cells protect H2O2-induced rat myoblasts via the miR-215/FABP3 pathway	5
Altered expression of EGFR and miR-34a derived from serum and tumoral tissue was associated with glioblastoma multiform	5
Mass spectrometry imaging of blast overpressure induced modulation of GABA/glutamate levels in the central auditory neuraxis of Chinchilla	5
Tissue distribution of stem cell factor in adults	5
Adverse effects of fetal exposure of electronic-cigarettes and high-fat diet on male neonatal hearts	5
WHO grading system for invasive pulmonary lung adenocarcinoma reveals distinct molecular signature: An analysis from the cancer genome atlas database	5
Mining the role of RECQL5 in gastric cancer and seeking potential regulatory network by bioinformatics analysis	5
ZNF677 downregulation by promoter hypermethylation as a driver event through gastric tumorigenesis	5
MCCC2 overexpression predicts poorer prognosis and promotes cell proliferation in colorectal cancer	5
SOX11-induced decrease in vimentin and an increase in prostate cancer cell migration attributed to cofilin activity	5
Alcohol: basic and translational research; 15th annual Charles Lieber &1st Samuel French satellite symposium	5
LncRNA CASC2 targets CAV1 by competitively binding with microRNA-194-5p to inhibit neonatal lung injury	5
Analysis of fibroblast genes selected by NMF to reveal the potential crosstalk between ulcerative colitis and colorectal cancer	5
Differential mobility spectrometry imaging for pathological applications	5
Skin remodeling and wound healing in the Gottingen minipig following exposure to sulfur mustard	5
B7-H4 expression promotes non-small cell lung cancer progression via AMPK/mTOR signaling	5
Human papillomavirus-positivity is associated with EREG down-regulation and promoter hypermethylation in head and neck squamous cell carcinoma	5
Senescence in a cell culture model for burn wounds	5
Increased expression of ALDH-1 is associated with clinical parameters of salivary glands neoplasms	5
Diversin upregulates the proliferative ability of colorectal cancer by inducing cell cycle proteins	5
Developmental changes induced by exogenous testosterone during early phases of prostate organogenesis	5
Therapeutic potentials of human microfluidic encapsulated conjunctival mesenchymal stem cells on the rat model of Parkinson's disease	5

Maternal mosaicism underlies the inheritance of a rare germline AKT3 variant which is responsible for megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome in two Roma half-siblings	5
TNF-α (rs1800629) polymorphism modifies the effect of sensitization to house dust mite on asthma and bronchial hyperresponsiveness in children	5
Immunohistochemical evidence of P2X7R, P2X4R and CaMKK2 in pyramidal neurons of frontal cortex does not align with Alzheimer's disease	4
Differential expression of preferentially expressed antigen in melanoma (PRAME) in testicular germ cell tumors – A comparative study with SOX17	4
The CTGF gene -945 G/C polymorphism is associated with target lesion revascularization for in-stent restenosis	4
Mutational heterogeneity between different regional tumour grades of clear cell renal cell carcinoma	4
NK1 receptor antagonistic effect of 17-trifluoromethyl phenyl trinor prostaglandin F2α on the growth of human breast cancer cell line	4
Alternations in mitochondrial genome in carcinogenesis of HPV positive cervix	4
Well-differentiated liposarcoma primary from thymic stroma: Case report and literature review	4
Regulation of CDK inhibitor p27 by microRNA 222 in breast cancer patients	4
Nuclear and stromal expression of Manic fringe in renal cell carcinoma	4
Gene expression with corresponding pathways analysis in Gaucher disease	4
The relationship between oxidative stress and cytogenetic abnormalities in B-cell chronic lymphocytic leukemia	4
Aquaporin3 (AQP3) expression in oral epithelium in oral lichen planus	4
MiR-4262 inhibits the development of esophageal cancer by negatively regulating KLF6 level	4
Single-cell transcriptomes identifies characteristic features of mouse macrophages in liver Mallory-Denk bodies formation	4
MicroRNA-575 acts as a novel oncogene via targeting multiple signaling pathways in glioblastoma	4
The temporal impact of erythropoietin administration on mitochondrial function and dynamics in cardiac ischemia/reperfusion injury	4
Determination of COL1A1–PDGFB breakpoints by next-generation sequencing in the molecular diagnosis of dermatofibrosarcoma protuberans	4
Validation of a next-generation sequencing assay for the detection of EGFR mutations in cell-free circulating tumor DNA	4
Patient-derived xenograft models for the study of benign human neoplasms	4
Phorbol 12-myristate 13-acetate stimulation under hypoxia induces nuclear swelling with DNA outflow but not extracellular trap formation of neutrophils	4
G-protein coupled receptor-associated sorting protein 1 (GASP-1), a ubiquitous tumor marker, promotes proliferation and invasion of triple negative breast cancer	4
Circ_ZFP644 attenuates caerulein-induced inflammatory injury in rat pancreatic acinar cells by modulating miR-106b/Pias3 axis	4
TLR4 rs1927914 polymorphism contributes to serum TLR4 levels in patients with aortic aneurysm	4
Roles of endothelial cells in the regulation of cell motility via lysophosphatidic acid receptor-2 (LPA2) and LPA3 in osteosarcoma cells	4
RETRACTED: LNCRNA Gas5 suppression protected Hl-1 cells against hypoxia injury by sponging Mir-222-3p	4
NF1 and PTEN gene polymorphisms and the susceptibility to soft tissue sarcomas in a Chinese population: A case-control study	4
Huagan tongluo Fang improves liver fibrosis via down-regulating miR-184 and up-regulating FOXO1 to inhibit Th17 cell differentiation	4