Experimental and Molecular Pathology

Article	Citations
ACE2 exhibits protective effects against LPS-induced acute lung injury in mice by inhibiting the LPS-TLR4 pathway	140
miRNA profile in ovarian cancer	90
Long non-coding RNA signature in gastric cancer	56
LEPR hypomethylation is significantly associated with gastric cancer in males	51
Neuro-protective roles of long non-coding RNA MALAT1 in Alzheimer's disease with the involvement of the microRNA-30b/CNR1 network and the following PI3K/AKT activation	49
Targeting miR-10a-5p/IL-6R axis for reducing IL-6-induced cartilage cell ferroptosis	47
Non-coding RNA profile in lung cancer	41
Type I astrocytes and microglia induce a cytokine response in an encephalitic murine coronavirus infection	40
LncRNA MALAT1 induces the dysfunction of β cells via reducing the histone acetylation of the PDX-1 promoter in type 1 diabetes	35
The role of activated leukocyte cell adhesion molecule (ALCAM) in cancer progression, invasion, metastasis and recurrence: A novel cancer stem cell marker and tumor-specific prognostic marker	33
Human umbilical cord mesenchymal stem cell-derived exosomes suppress dermal fibroblasts-myofibroblats transition via inhibiting the TGF-β1/Smad 2/3 signaling pathway	33
LncRNA GAS5 suppresses inflammatory responses and apoptosis of alveolar epithelial cells by targeting miR-429/DUSP1	30
MicroRNA-199a-3p inhibits angiogenesis by targeting the VEGF/PI3K/AKT signalling pathway in an in vitro model of diabetic retinopathy	29
MiRNA-339-5p suppresses the malignant development of gastric cancer via targeting ALKBH1	29
The PI3K/AKT signaling pathway in cancer: Molecular mechanisms and possible therapeutic interventions	28
RETRACTED: Aberrant expression of lncRNA MALAT1 modulates radioresistance in colorectal cancer in vitro via miR-101-3p sponging	27
The alterations of mitochondrial DNA in coronary heart disease	26
MiR-1258 promotes the apoptosis of cervical cancer cells by regulating the E2F1/P53 signaling pathway	26
miRNA signature in glioblastoma: Potential biomarkers and therapeutic targets	26
LncRNAs and miRNAs participate in determination of sensitivity of cancer cells to cisplatin	26
Long non-coding RNA muskelin 1 antisense RNA (MKLN1-AS) is a potential diagnostic and prognostic biomarker and therapeutic target for hepatocellular carcinoma	24
The critical roles of lncRNAs in the pathogenesis of melanoma	24
MiR-302a-3p aggravates myocardial ischemia-reperfusion injury by suppressing mitophagy via targeting FOXO3	24
Expression analysis of vimentin and the related lncRNA network in breast cancer	23
LncRNA SNHG1 contributes to the cisplatin resistance and progression of NSCLC via miR-330-5p/DCLK1 axis	23

Therapeutic potential of mesenchymal stem cell-derived extracellular vesicles as novel cell-free therapy for treatment of autoimmune disorders	21
The role of genetic polymorphism within PD-L1 gene in cancer. Review	21
Dual role of heme iron in cancer; promotor of carcinogenesis and an inducer of tumour suppression	21
Long non-coding RNA ROR sponges miR-138 to aggravate hypoxia/reoxygenation-induced cardiomyocyte apoptosis via upregulating Mst1	20
Circ_DCAF6 potentiates cell stemness and growth in breast cancer through GLI1-Hedgehog pathway	20
The clinicomolecular landscape of de novo versus relapsed stage IV metastatic breast cancer	19
Long non-coding RNA HAGLROS regulates lipid metabolism reprogramming in intrahepatic cholangiocarcinoma via the mTOR signaling pathway	19
LncRNA KCNQ1OT1 contributes to cardiomyocyte apoptosis by targeting FUS in heart failure	19
1,25(OH)2D3 provides protection against diabetic kidney disease by downregulating the TLR4-MyD88-NF-κB pathway	19
Astragaloside-IV regulates endoplasmic reticulum stress-mediated neuronal apoptosis in a murine model of Parkinson's disease via the lincRNA-p21/CHOP pathway	18
Circ-ITCH restrains the expression of MMP-2, MMP-9 and TNF-α in diabetic retinopathy by inhibiting miR-22	18
Circ_AFF2 facilitates proliferation and inflammatory response of fibroblast-like synoviocytes in rheumatoid arthritis via the miR-375/TAB2 axis	18
Dexmedetomidine protects intestinal ischemia-reperfusion injury via inhibiting p38 MAPK cascades	18
The role and function of long non-coding RNAs in osteoarthritis	18
Ghrelin protects against obesity-induced myocardial injury by regulating the lncRNA H19/miR-29a/IGF-1 signalling axis	17
New insights into long non-coding RNAs in breast cancer: Biological functions and therapeutic prospects	17
LncRNA PCGEM1 enhances metastasis and gastric cancer invasion through targeting of miR-129-5p to regulate P4HA2 expression	17
TGF-β1 signaling can worsen NAFLD with liver fibrosis backdrop	17
Effect of aberrant DNA methylation on cancer stem cell properties	17
Regulatory effect of LncRNA DRAIC/miR-149-5p/NFIB molecular network on autophagy of esophageal cancer cells and its biological behavior	17
Cytokeratin 7 and cytokeratin 20 expression in cancer: A tissue microarray study on 15,424 cancers	16
Enhanced expression of lncRNA ZXF1 promotes cisplatin resistance in lung cancer cell via MAPK axis	16
miR-133 inhibits proliferation and promotes apoptosis by targeting LASP1 in lupus nephritis	16
Assessment of CMKLR1 level in colorectal cancer and its correlation with angiogenic markers	16
Dexmedetomidine reduces the inflammation and apoptosis of doxorubicin-induced myocardial cells	16
Circ-XPO1 upregulates XPO1 expression by sponging multiple miRNAs to facilitate osteosarcoma cell progression	15
Effect of astaxanthin on metabolic cataract in rats with type 1 diabetes mellitus	15
Icariside II attenuates eosinophils-induced airway inflammation and remodeling via inactivation of NF-κB and STAT3 in an asthma mouse model	15
Roles of a TMPO-AS1/microRNA-200c/TMEFF2 ceRNA network in the malignant behaviors and 5-FU resistance of ovarian cancer cells	15
microRNA-216a protects against human retinal microvascular endothelial cell injury in diabetic retinopathy by suppressing the NOS2/JAK/STAT axis	15
FOXM1-induced upregulation of lncRNA OR3A4 promotes the progression of diffuse large B-cell lymphoma via Wnt/β-catenin signaling pathway	15
Propofol alleviates ventilator-induced lung injury through regulating the Nrf2/NLRP3 signaling pathway	15
DYNLL1 is hypomethylated and upregulated in a tumor stage- and grade-dependent manner and associated with increased mortality in hepatocellular carcinoma	15
Interference of miR-212 and miR-384 promotes osteogenic differentiation via targeting RUNX2 in osteoporosis	14
Mortalin promotes breast cancer malignancy	14
Down-regulation of long noncoding RNA LINC00472 alleviates sepsis-induced acute hepatic injury by regulating miR-373-3p/TRIM8 axis	14
HIF-1α/SDF-1/CXCR4 axis reduces neuronal apoptosis via enhancing the bone marrow-derived mesenchymal stromal cell migration in rats with traumatic brain injury	14
MiR-195 suppression alleviates apoptosis and oxidative stress in CCl4-induced ALI in mice by targeting Pim-1	14
Association of DNA repair gene polymorphisms with colorectal cancer risk and treatment outcomes	14
The PI3K-AKT pathway: A plausible therapeutic target in Parkinson's disease	14
Long non-coding RNA H19 in the liver-gut axis: A diagnostic marker and therapeutic target for liver diseases	14
Expression assessment of a panel of long non-coding RNAs in gastric malignancy	14
CircWHSC1 regulates malignancy and glycolysis by the miR-212-5p/AKT3 pathway in triple-negative breast cancer	13
The cell theory and cellular pathology: Discovery, refinements and applications fundamental to advances in biology and medicine	13
Up-regulation of miRNA-151-3p enhanced the neuroprotective effect of dexmedetomidine against β-amyloid by targeting DAPK-1 and TP53	13
Smad2 and Smad3 play antagonistic roles in high glucose-induced renal tubular fibrosis via the regulation of SnoN	13
RETRACTED: Knockdown of long non-coding RNA CCAT1 suppresses proliferation and EMT of human cervical cancer cell lines by down-regulating Runx2	13
miR-188-5p inhibits apoptosis of neuronal cells during oxygen-glucose deprivation (OGD)-induced stroke by suppressing PTEN	12
Prognostic and clinicopathological significance of TMEFF2, SMOC-2, and SOX17 expression in endometrial carcinoma	12
miRNA microarray profiling in patients with androgenic alopecia and the effects of miR-133b on hair growth	12

PCAT1: An oncogenic lncRNA in diverse cancers and a putative therapeutic target	12
Long noncoding RNA LINC00978 acts as a potential diagnostic biomarker in patients with colorectal cancer	12
Role of RBM3 in the regulation of cell proliferation in hepatocellular carcinoma	12
Protective effect of dapsone against bleomycin-induced lung fibrosis in rat	12
Down-regulation of the human major histocompatibility complex class I chain-related gene A (MICA) and its receptor is mediated by microRNA-146b-5p and is a potential mechanism of immunoediting in papi	12
TIPE2 suppressed cisplatin resistance by inducing autophagy via mTOR signalling pathway	11
Cathelicidin attenuates hyperoxia-induced intestinal injury through inhibition of NF-κB activity in newborn rats	11
Novel Biocartis Idylla™ cartridge-based assay for detection of microsatellite instability in colorectal cancer tissues	11
Nitroglycerin ameliorates sperm parameters, oxidative stress and testicular injury following by testicular torsion/detorsion in male rats	11
Circ-E2F3 acts as a ceRNA for miR-204-5p to promote proliferation, metastasis and apoptosis inhibition in retinoblastoma by regulating ROCK1 expression	11
Ataxia telangiectasia mutated pathway disruption affects hepatic DNA and tissue damage in nonalcoholic fatty liver disease	11
B7-H4 is a potential prognostic biomarker of prostate cancer	11
MicroRNA-29a functions as a tumor suppressor through targeting STAT3 in laryngeal squamous cell carcinoma	10
Targeted next generation sequencing panel for HPV genotyping in cervical cancer	10
A novel prognostic index of stomach adenocarcinoma based on immunogenomic landscape analysis and immunotherapy options	10
miR-200c increases the sensitivity of breast cancer cells to Doxorubicin through downregulating MDR1 gene	10
Analysis on the expression and value of CCL2 and CCL3 in patients with osteoarthritis	10
HBXIP accelerates glycolysis and promotes cancer angiogenesis via AKT/mTOR pathway in bladder cancer	10
RETRACTED: The effect of LncRNA SNHG16 on vascular smooth muscle cells in CHD by targeting miRNA-218-5p	10
PRR34-AS1 sponges miR-498 to facilitate TOMM20 and ITGA6 mediated tumor progression in HCC	10
Bile acids aggravate nonalcoholic steatohepatitis and cardiovascular disease in SHRSP5/Dmcr rat model	10
Atrial fibrosis and decreased connexin 43 in rat hearts after exposure to high-intensity infrasound	10
Role of miRNAs in conveying message of stem cells via extracellular vesicles	10
Standardization of diethylnitrosamine-induced hepatocellular carcinoma rat model with time based molecular assessment	10
The regulatory role of SFRP5/WNT5A axis in allergic rhinitis through inhibiting JNK pathway activation and lowering mucin generation in human nasal epithelial cells	10
The pleiotropic peroxisome proliferator activated receptors: Regulation and therapeutics	10
Clinical implementation of plasma EGFR T790M testing using droplet digital PCR in TKI-resistant NSCLC patients	9
Gene expression of indoleamine and tryptophan dioxygenases and three long non-coding RNAs in breast cancer	9
RETRACTED: Low-expressed GAS5 injure myocardial cells and progression of chronic heart failure via regulation of miR-223-3P	9
MiR-93/HMGB3 regulatory axis exerts tumor suppressive effects in colorectal carcinoma cells	9
Elevated circRNAs circ_0000745, circ_0001531 and circ_0001640 in human whole blood: Potential novel diagnostic biomarkers for breast cancer	9
Aluminum exposure promotes histopathological and pro-oxidant damage to the prostate and gonads of male and female adult gerbils	9
Effect of fibroblast growth factor 2 on degenerative endplate chondrocyte: From anabolism to catabolism	9
Inhibition of miR-1224 suppresses hypoxia/reoxygenation-induced oxidative stress and apoptosis in cardiomyocytes through targeting GPX4	9
Central nervous system (CNS) tumor cell heterogeneity contributes to differential platinum-based response in an in vitro 2D and 3D cell culture approach	9
Overexpression of CD200 and CD123 is a major influential factor in the clinical course of pediatric acute myeloid leukemia	9
LINC00665 activates Wnt/β-catenin signaling pathway to facilitate tumor progression of colorectal cancer via upregulating CTNNB1	9
Feasibility and clinical utility of a pan-solid tumor targeted RNA fusion panel: A single center experience	9
Comparative expression of immunohistochemical biomarkers in cribriform and pattern 4 non-cribriform prostatic adenocarcinoma	9
Important role of annexin A2 (ANXA2) in new blood vessel development in vivo and human triple negative breast cancer (TNBC) growth	9
Sarcopenia, oxidative stress and inflammatory process in muscle of cirrhotic rats – Action of melatonin and physical exercise	9
Dual biomarkers long non-coding RNA GAS5 and its target, NR3C1, contribute to acute myeloid leukemia	9
miR-155 facilitates calcium oxalate crystal-induced HK-2 cell injury via targeting PI3K associated autophagy	8
Sirt2 positively regulates muscle regeneration after Notexin-induced muscle injury	8
The coding microsatellite mutation profile of PMS2-deficient colorectal cancer	8
High prevalence of ROS1 gene rearrangement detected by FISH in EGFR and ALK negative lung adenocarcinoma	8
Perinatal exposure to bisphenol A impacts in the mammary gland morphology of adult Mongolian gerbils	8
Long noncoding RNA-GAS5 retards renal fibrosis through repressing miR-21 activity	8
HOX transcript antisense RNA: An oncogenic lncRNA in diverse malignancies	8
SETD8 promotes stemness characteristics and is a potential prognostic biomarker of gastric adenocarcinoma	8
Expression profiling revealed up-regulation of three lncRNAs in breast cancer samples.	8
Antioxidant/stress response in mouse epidermis following exposure to nitrogen mustard	8
DROSHA rs10719 and DICER1 rs3742330 polymorphisms in endometriosis and different diseases: Case-control and review studies.	8
Down-regulation of lncRNA PCGEM1 inhibits cervical carcinoma by modulating the miR-642a-5p/LGMN axis	8
Role of different Th17 and Treg downstream signalling pathways in the pathogenesis of Staphylococcus aureus infection induced septic arthritis in mice	8
Transcriptome profiling and pathway analysis in squamous cell carcinoma of buccal mucosa	8
MiR-487a-3p suppresses the malignant development of pancreatic cancer by targeting SMAD7	8
Investigating the regulatory function of the ANO1-AS2 on the ANO1 gene in infertile men with asthenozoospermia and terato-asthenozoospermia	8
Ranolazine alleviated cardiac/brain dysfunction in doxorubicin-treated rats	7
Nucleotide-binding oligomerization domain protein 1 enhances oxygen-glucose deprivation and reperfusion injury in cortical neurons via activation of endoplasmic reticulum stress-mediated autophagy	7
Characterization of the rabbit conjunctiva: Effects of sulfur mustard	7
Remote ischemic postconditioning attenuates damage in rats with chronic cerebral ischemia by upregulating the autophagolysosome pathway via the activation of TFEB	7
The role of the peritoneal microenvironment in the pathogenesis of colorectal peritoneal carcinomatosis	7
Tumour suppressor role of microRNA-335-5p in esophageal squamous cell carcinoma by targeting TTK (Mps1)	7
Effects of miR-599 targeting YAP1 on proliferation, invasion and apoptosis of bladder urothelial carcinoma cells	7
Antihyperglycemic activity of L-norvaline and L-arginine in high-fat diet and streptozotocin-treated male rats	7
Long non-coding RNA Hsp4 alleviates lipopolysaccharide-induced apoptosis of lung epithelial cells via miRNA-466m-3p/DNAjb6 axis	6
DICER-AS1 lncRNA: A putative culprit in the pathogenesis of gastric cancer	6
RETRACTED: Loss of microRNA-30e induced by extracellular vesicles from cancer-associated fibroblasts promotes breast cancer progression by binding to CTHRC1	6
SMAD7 and SMAD4 expression in colorectal cancer progression and therapy response	6
Nodular fasciitis of the breast: Report of two cases illustrating the diagnostic implications for USP6 gene rearrangement and brief review of the literature	6
Critical roles of microRNA-196 in normal physiology and non-malignant diseases: Diagnostic and therapeutic implications	6
HSPB8 promoted intrahepatic cholangiocarcinoma progression by enhancing epithelial-mesenchymal transition and autophagy	6
Expression of activator proteins of SHH/GLI and PI3K/Akt/mTORC1 signaling pathways in human gliomas is associated with high grade tumors	6
CD4+ T cells and TGFβ1/MAPK signal pathway involved in the valvular hyperblastosis and fibrosis in patients with rheumatic heart disease	6
Fragmentation assessment of FFPE DNA helps in evaluating NGS library complexity and interpretation of NGS results	6
Comparison of Biocartis IDYLLA ™ cartridge assay with Qiagen GeneReader NGS for detection of targetable mutations in EGFR, KRAS/NRAS, and BRAF genes	6
Dysregulation of non-coding RNAs in autoimmune thyroid disease	6
Human primary chronic wound derived fibroblasts demonstrate differential pattern in expression of fibroblast specific markers, cell cycle arrest and reduced proliferation	6
Autophagy and immune microenvironment in craniopharyngioma and ameloblastoma	6

Integrated analysis of multiple microarray studies to identify potential pathogenic gene modules in preeclampsia	6
B7-H4 expression promotes non-small cell lung cancer progression via AMPK/mTOR signaling	5
Lung metastases and subsequent malignant transformation of a fumarate hydratase -deficient uterine leiomyoma	5
The role of cell surface proteins gene expression in diagnosis, prognosis, and drug resistance of colorectal cancer: In silico analysis and validation	5
Pimitespib is effective on cecal GIST in a mouse model of familial GISTs with KIT-Asp820Tyr mutation through KIT signaling inhibition	5
Developmental changes induced by exogenous testosterone during early phases of prostate organogenesis	5
Therapeutic potentials of human microfluidic encapsulated conjunctival mesenchymal stem cells on the rat model of Parkinson's disease	5
Human papillomavirus-positivity is associated with EREG down-regulation and promoter hypermethylation in head and neck squamous cell carcinoma	5
ESRG, LINC00518 and PWRN1 are newly-identified deregulated lncRNAs in colorectal cancer	5
ZNF677 downregulation by promoter hypermethylation as a driver event through gastric tumorigenesis	5
Expression and change of miR-199b-5p, s HLA-G in thyroid carcinoma	5
MCCC2 overexpression predicts poorer prognosis and promotes cell proliferation in colorectal cancer	5
Mass spectrometry imaging of blast overpressure induced modulation of GABA/glutamate levels in the central auditory neuraxis of Chinchilla	5
Effects of acute noise exposure on DNA damage response genes in the cochlea, cortex, heart and liver	5
HOXB2 and FOXC1 synergistically drive the progression of Wilms tumor	5
ADAM7 promotes the proliferation and invasion in trophoblast cells	5
Maternal mosaicism underlies the inheritance of a rare germline AKT3 variant which is responsible for megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome in two Roma half-siblings	5
Functional roles of exosomal miRNAs in multi-drug resistance in cancer chemotherapeutics	5
WHO grading system for invasive pulmonary lung adenocarcinoma reveals distinct molecular signature: An analysis from the cancer genome atlas database	5
The biogenesis, biological functions and modification of Circular RNAs	5
Increased expression of ALDH-1 is associated with clinical parameters of salivary glands neoplasms	5
Antiandrogen abiraterone and docetaxel treatments affect Notch1, Jagged1 and Hes1 expressions in metastatic prostate cancer cells	5
LncRNA CASC2 targets CAV1 by competitively binding with microRNA-194-5p to inhibit neonatal lung injury	5
Targeted-regulating of miR-515-5p by LncRNA LOXL1-AS1 on the proliferation and migration of trophoblast cells	5
LncRNA RHPN1-AS1 promotes the progression of nasopharyngeal carcinoma by targeting CELF2 expression	5
Differential mobility spectrometry imaging for pathological applications	5
Mining the role of RECQL5 in gastric cancer and seeking potential regulatory network by bioinformatics analysis	5
Alternations in mitochondrial genome in carcinogenesis of HPV positive cervix	4
TLR4 rs1927914 polymorphism contributes to serum TLR4 levels in patients with aortic aneurysm	4
Neuregulin 1/ErbB4/Akt signaling attenuates cytotoxicity mediated by the APP-CT31 fragment of amyloid precursor protein	4
RETRACTED: LNCRNA Gas5 suppression protected Hl-1 cells against hypoxia injury by sponging Mir-222-3p	4
Well-differentiated liposarcoma primary from thymic stroma: Case report and literature review	4
Huagan tongluo Fang improves liver fibrosis via down-regulating miR-184 and up-regulating FOXO1 to inhibit Th17 cell differentiation	4
Regulation of CDK inhibitor p27 by microRNA 222 in breast cancer patients	4
Validation of a next-generation sequencing assay for the detection of EGFR mutations in cell-free circulating tumor DNA	4
Nuclear and stromal expression of Manic fringe in renal cell carcinoma	4
The inhibitory effect and safety of GANT61 on HeLa cells in nude mice	4
The CTGF gene -945 G/C polymorphism is associated with target lesion revascularization for in-stent restenosis	4
Circ_ZFP644 attenuates caerulein-induced inflammatory injury in rat pancreatic acinar cells by modulating miR-106b/Pias3 axis	4
NK1 receptor antagonistic effect of 17-trifluoromethyl phenyl trinor prostaglandin F2α on the growth of human breast cancer cell line	4
MiR-4262 inhibits the development of esophageal cancer by negatively regulating KLF6 level	4
Mutational heterogeneity between different regional tumour grades of clear cell renal cell carcinoma	4
MicroRNA-575 acts as a novel oncogene via targeting multiple signaling pathways in glioblastoma	4
Elevated TLR5 expression in vivo and loss of NF-κΒ activation via TLR5 in vitro detected in HPV-negative oropharyngeal squamous cell carcinoma	4
Determination of COL1A1–PDGFB breakpoints by next-generation sequencing in the molecular diagnosis of dermatofibrosarcoma protuberans	4
Gene expression with corresponding pathways analysis in Gaucher disease	4
Differential expression of preferentially expressed antigen in melanoma (PRAME) in testicular germ cell tumors – A comparative study with SOX17	4
Exosomes isolated from the miR-215-modified bone marrow mesenchymal stem cells protect H2O2-induced rat myoblasts via the miR-215/FABP3 pathway	4
Downregulation of MicroRNA-494 inhibits the TGF-β1/Smads signaling pathway and prevents the development of hypospadias through upregulating Nedd4L	4
Alcohol: basic and translational research; 15th annual Charles Lieber &1st Samuel French satellite symposium	4
Single-cell transcriptomes identifies characteristic features of mouse macrophages in liver Mallory-Denk bodies formation	4
Analysis of fibroblast genes selected by NMF to reveal the potential crosstalk between ulcerative colitis and colorectal cancer	4
Tissue distribution of stem cell factor in adults	4
Adverse effects of fetal exposure of electronic-cigarettes and high-fat diet on male neonatal hearts	4
TNF-α (rs1800629) polymorphism modifies the effect of sensitization to house dust mite on asthma and bronchial hyperresponsiveness in children	4
NF1 and PTEN gene polymorphisms and the susceptibility to soft tissue sarcomas in a Chinese population: A case-control study	4
Immunohistochemical evidence of P2X7R, P2X4R and CaMKK2 in pyramidal neurons of frontal cortex does not align with Alzheimer's disease	4
Patient-derived xenograft models for the study of benign human neoplasms	4
SOX11-induced decrease in vimentin and an increase in prostate cancer cell migration attributed to cofilin activity	4
Altered expression of EGFR and miR-34a derived from serum and tumoral tissue was associated with glioblastoma multiform	4