OOIR: Observatory of International Research

Papers

(The median citation count of Experimental and Molecular Pathology is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Neuro-protective roles of long non-coding RNA MALAT1 in Alzheimer's disease with the involvement of the microRNA-30b/CNR1 network and the following PI3K/AKT activation	55
Targeting miR-10a-5p/IL-6R axis for reducing IL-6-induced cartilage cell ferroptosis	49
The PI3K/AKT signaling pathway in cancer: Molecular mechanisms and possible therapeutic interventions	37
LncRNAs and miRNAs participate in determination of sensitivity of cancer cells to cisplatin	34
miRNA signature in glioblastoma: Potential biomarkers and therapeutic targets	30
Long non-coding RNA muskelin 1 antisense RNA (MKLN1-AS) is a potential diagnostic and prognostic biomarker and therapeutic target for hepatocellular carcinoma	28
The PI3K-AKT pathway: A plausible therapeutic target in Parkinson's disease	28
Therapeutic potential of mesenchymal stem cell-derived extracellular vesicles as novel cell-free therapy for treatment of autoimmune disorders	27
Dual role of heme iron in cancer; promotor of carcinogenesis and an inducer of tumour suppression	26
The critical roles of lncRNAs in the pathogenesis of melanoma	26
MiR-302a-3p aggravates myocardial ischemia-reperfusion injury by suppressing mitophagy via targeting FOXO3	25
TGF-β1 signaling can worsen NAFLD with liver fibrosis backdrop	24
Cytokeratin 7 and cytokeratin 20 expression in cancer: A tissue microarray study on 15,424 cancers	24
LncRNA SNHG1 contributes to the cisplatin resistance and progression of NSCLC via miR-330-5p/DCLK1 axis	23
Circ-ITCH restrains the expression of MMP-2, MMP-9 and TNF-α in diabetic retinopathy by inhibiting miR-22	22
Effect of aberrant DNA methylation on cancer stem cell properties	19
Circ_AFF2 facilitates proliferation and inflammatory response of fibroblast-like synoviocytes in rheumatoid arthritis via the miR-375/TAB2 axis	19
Mortalin promotes breast cancer malignancy	18
CircWHSC1 regulates malignancy and glycolysis by the miR-212-5p/AKT3 pathway in triple-negative breast cancer	17
New insights into long non-coding RNAs in breast cancer: Biological functions and therapeutic prospects	17
Protective effect of dapsone against bleomycin-induced lung fibrosis in rat	17
Circ-XPO1 upregulates XPO1 expression by sponging multiple miRNAs to facilitate osteosarcoma cell progression	17
DYNLL1 is hypomethylated and upregulated in a tumor stage- and grade-dependent manner and associated with increased mortality in hepatocellular carcinoma	17
The cell theory and cellular pathology: Discovery, refinements and applications fundamental to advances in biology and medicine	16
Down-regulation of long noncoding RNA LINC00472 alleviates sepsis-induced acute hepatic injury by regulating miR-373-3p/TRIM8 axis	16

Up-regulation of miRNA-151-3p enhanced the neuroprotective effect of dexmedetomidine against β-amyloid by targeting DAPK-1 and TP53	14
miRNA microarray profiling in patients with androgenic alopecia and the effects of miR-133b on hair growth	14
HBXIP accelerates glycolysis and promotes cancer angiogenesis via AKT/mTOR pathway in bladder cancer	13
Sarcopenia, oxidative stress and inflammatory process in muscle of cirrhotic rats – Action of melatonin and physical exercise	13
Analysis on the expression and value of CCL2 and CCL3 in patients with osteoarthritis	13
Long noncoding RNA LINC00978 acts as a potential diagnostic biomarker in patients with colorectal cancer	13
Prognostic and clinicopathological significance of TMEFF2, SMOC-2, and SOX17 expression in endometrial carcinoma	13
Role of RBM3 in the regulation of cell proliferation in hepatocellular carcinoma	13
A novel prognostic index of stomach adenocarcinoma based on immunogenomic landscape analysis and immunotherapy options	12
Antihyperglycemic activity of L-norvaline and L-arginine in high-fat diet and streptozotocin-treated male rats	12
Targeted next generation sequencing panel for HPV genotyping in cervical cancer	12
Circ-E2F3 acts as a ceRNA for miR-204-5p to promote proliferation, metastasis and apoptosis inhibition in retinoblastoma by regulating ROCK1 expression	12
Nitroglycerin ameliorates sperm parameters, oxidative stress and testicular injury following by testicular torsion/detorsion in male rats	12
High prevalence of ROS1 gene rearrangement detected by FISH in EGFR and ALK negative lung adenocarcinoma	12
The coding microsatellite mutation profile of PMS2-deficient colorectal cancer	11
PRR34-AS1 sponges miR-498 to facilitate TOMM20 and ITGA6 mediated tumor progression in HCC	11
The regulatory role of SFRP5/WNT5A axis in allergic rhinitis through inhibiting JNK pathway activation and lowering mucin generation in human nasal epithelial cells	11
Overexpression of CD200 and CD123 is a major influential factor in the clinical course of pediatric acute myeloid leukemia	11
HOX transcript antisense RNA: An oncogenic lncRNA in diverse malignancies	11
miR-200c increases the sensitivity of breast cancer cells to Doxorubicin through downregulating MDR1 gene	11
The pleiotropic peroxisome proliferator activated receptors: Regulation and therapeutics	11
The biogenesis, biological functions and modification of Circular RNAs	10
RETRACTED: The effect of LncRNA SNHG16 on vascular smooth muscle cells in CHD by targeting miRNA-218-5p	10
MiR-93/HMGB3 regulatory axis exerts tumor suppressive effects in colorectal carcinoma cells	10
LINC00665 activates Wnt/β-catenin signaling pathway to facilitate tumor progression of colorectal cancer via upregulating CTNNB1	10
DROSHA rs10719 and DICER1 rs3742330 polymorphisms in endometriosis and different diseases: Case-control and review studies.	10
Effect of fibroblast growth factor 2 on degenerative endplate chondrocyte: From anabolism to catabolism	10
Standardization of diethylnitrosamine-induced hepatocellular carcinoma rat model with time based molecular assessment	10
Role of miRNAs in conveying message of stem cells via extracellular vesicles	10
Tumour suppressor role of microRNA-335-5p in esophageal squamous cell carcinoma by targeting TTK (Mps1)	10
Inhibition of miR-1224 suppresses hypoxia/reoxygenation-induced oxidative stress and apoptosis in cardiomyocytes through targeting GPX4	10
RETRACTED: Low-expressed GAS5 injure myocardial cells and progression of chronic heart failure via regulation of miR-223-3P	10
Sirt2 positively regulates muscle regeneration after Notexin-induced muscle injury	10
Elevated circRNAs circ_0000745, circ_0001531 and circ_0001640 in human whole blood: Potential novel diagnostic biomarkers for breast cancer	10
Down-regulation of lncRNA PCGEM1 inhibits cervical carcinoma by modulating the miR-642a-5p/LGMN axis	9
Investigating the regulatory function of the ANO1-AS2 on the ANO1 gene in infertile men with asthenozoospermia and terato-asthenozoospermia	9
Human primary chronic wound derived fibroblasts demonstrate differential pattern in expression of fibroblast specific markers, cell cycle arrest and reduced proliferation	9
Expression profiling revealed up-regulation of three lncRNAs in breast cancer samples.	9
Ranolazine alleviated cardiac/brain dysfunction in doxorubicin-treated rats	9
ESRG, LINC00518 and PWRN1 are newly-identified deregulated lncRNAs in colorectal cancer	9
SETD8 promotes stemness characteristics and is a potential prognostic biomarker of gastric adenocarcinoma	8
Dysregulation of non-coding RNAs in autoimmune thyroid disease	8
Fragmentation assessment of FFPE DNA helps in evaluating NGS library complexity and interpretation of NGS results	8
A review of the critical role of vitamin D axis on the immune system	8
The role of cell surface proteins gene expression in diagnosis, prognosis, and drug resistance of colorectal cancer: In silico analysis and validation	8
Phloretin enhances autophagy by impairing AKT activation and inducing JNK-Beclin-1 pathway activation	8
SMAD7 and SMAD4 expression in colorectal cancer progression and therapy response	8
Autophagy and immune microenvironment in craniopharyngioma and ameloblastoma	7
Lung metastases and subsequent malignant transformation of a fumarate hydratase -deficient uterine leiomyoma	7
Characterization of the rabbit conjunctiva: Effects of sulfur mustard	7

Effects of miR-599 targeting YAP1 on proliferation, invasion and apoptosis of bladder urothelial carcinoma cells	7
Integrated analysis of multiple microarray studies to identify potential pathogenic gene modules in preeclampsia	7
HSPB8 promoted intrahepatic cholangiocarcinoma progression by enhancing epithelial-mesenchymal transition and autophagy	7
Nucleotide-binding oligomerization domain protein 1 enhances oxygen-glucose deprivation and reperfusion injury in cortical neurons via activation of endoplasmic reticulum stress-mediated autophagy	7
Critical roles of microRNA-196 in normal physiology and non-malignant diseases: Diagnostic and therapeutic implications	7
RETRACTED: Loss of microRNA-30e induced by extracellular vesicles from cancer-associated fibroblasts promotes breast cancer progression by binding to CTHRC1	6
Expression and change of miR-199b-5p, s HLA-G in thyroid carcinoma	6
Antiandrogen abiraterone and docetaxel treatments affect Notch1, Jagged1 and Hes1 expressions in metastatic prostate cancer cells	6
Comparison of Biocartis IDYLLA ™ cartridge assay with Qiagen GeneReader NGS for detection of targetable mutations in EGFR, KRAS/NRAS, and BRAF genes	6
Expression of activator proteins of SHH/GLI and PI3K/Akt/mTORC1 signaling pathways in human gliomas is associated with high grade tumors	6
LncRNA RHPN1-AS1 promotes the progression of nasopharyngeal carcinoma by targeting CELF2 expression	6
miR-876-3p suppresses the progression of colon cancer and correlates the prognosis of patients	6
Pimitespib is effective on cecal GIST in a mouse model of familial GISTs with KIT-Asp820Tyr mutation through KIT signaling inhibition	6
Neuregulin 1/ErbB4/Akt signaling attenuates cytotoxicity mediated by the APP-CT31 fragment of amyloid precursor protein	6
Functional roles of exosomal miRNAs in multi-drug resistance in cancer chemotherapeutics	6
Nodular fasciitis of the breast: Report of two cases illustrating the diagnostic implications for USP6 gene rearrangement and brief review of the literature	6
Long non-coding RNA Hsp4 alleviates lipopolysaccharide-induced apoptosis of lung epithelial cells via miRNA-466m-3p/DNAjb6 axis	6
Roles of endothelial cells in the regulation of cell motility via lysophosphatidic acid receptor-2 (LPA2) and LPA3 in osteosarcoma cells	6
Targeted-regulating of miR-515-5p by LncRNA LOXL1-AS1 on the proliferation and migration of trophoblast cells	6
TLR4 rs1927914 polymorphism contributes to serum TLR4 levels in patients with aortic aneurysm	5
WHO grading system for invasive pulmonary lung adenocarcinoma reveals distinct molecular signature: An analysis from the cancer genome atlas database	5
Adverse effects of fetal exposure of electronic-cigarettes and high-fat diet on male neonatal hearts	5
B7-H4 expression promotes non-small cell lung cancer progression via AMPK/mTOR signaling	5
Human papillomavirus-positivity is associated with EREG down-regulation and promoter hypermethylation in head and neck squamous cell carcinoma	5
Exosomes isolated from the miR-215-modified bone marrow mesenchymal stem cells protect H2O2-induced rat myoblasts via the miR-215/FABP3 pathway	5
Senescence in a cell culture model for burn wounds	5
Mass spectrometry imaging of blast overpressure induced modulation of GABA/glutamate levels in the central auditory neuraxis of Chinchilla	5
Alternations in mitochondrial genome in carcinogenesis of HPV positive cervix	5
Therapeutic potentials of human microfluidic encapsulated conjunctival mesenchymal stem cells on the rat model of Parkinson's disease	5
Differential mobility spectrometry imaging for pathological applications	5
ADAM7 promotes the proliferation and invasion in trophoblast cells	5
Differential expression of preferentially expressed antigen in melanoma (PRAME) in testicular germ cell tumors – A comparative study with SOX17	5
SOX11-induced decrease in vimentin and an increase in prostate cancer cell migration attributed to cofilin activity	5
Alcohol: basic and translational research; 15th annual Charles Lieber &1st Samuel French satellite symposium	5
LncRNA CASC2 targets CAV1 by competitively binding with microRNA-194-5p to inhibit neonatal lung injury	5
Tissue distribution of stem cell factor in adults	5
Analysis of fibroblast genes selected by NMF to reveal the potential crosstalk between ulcerative colitis and colorectal cancer	5
Regulation of CDK inhibitor p27 by microRNA 222 in breast cancer patients	5
ZNF677 downregulation by promoter hypermethylation as a driver event through gastric tumorigenesis	5
Phorbol 12-myristate 13-acetate stimulation under hypoxia induces nuclear swelling with DNA outflow but not extracellular trap formation of neutrophils	5
Increased expression of ALDH-1 is associated with clinical parameters of salivary glands neoplasms	5
Diversin upregulates the proliferative ability of colorectal cancer by inducing cell cycle proteins	5
Altered expression of EGFR and miR-34a derived from serum and tumoral tissue was associated with glioblastoma multiform	5
Immunohistochemical evidence of P2X7R, P2X4R and CaMKK2 in pyramidal neurons of frontal cortex does not align with Alzheimer's disease	4
Patient-derived xenograft models for the study of benign human neoplasms	4
The CTGF gene -945 G/C polymorphism is associated with target lesion revascularization for in-stent restenosis	4
NK1 receptor antagonistic effect of 17-trifluoromethyl phenyl trinor prostaglandin F2α on the growth of human breast cancer cell line	4
NF1 and PTEN gene polymorphisms and the susceptibility to soft tissue sarcomas in a Chinese population: A case-control study	4
Gene expression with corresponding pathways analysis in Gaucher disease	4
G-protein coupled receptor-associated sorting protein 1 (GASP-1), a ubiquitous tumor marker, promotes proliferation and invasion of triple negative breast cancer	4
Circ_ZFP644 attenuates caerulein-induced inflammatory injury in rat pancreatic acinar cells by modulating miR-106b/Pias3 axis	4
Expression of immunoproteasome subunits in the brains of Toxoplasma gondii-infected mice	4
Determination of COL1A1–PDGFB breakpoints by next-generation sequencing in the molecular diagnosis of dermatofibrosarcoma protuberans	4
Validation of a next-generation sequencing assay for the detection of EGFR mutations in cell-free circulating tumor DNA	4
Nuclear and stromal expression of Manic fringe in renal cell carcinoma	4
A PHF1-TFE3 fusion atypical ossifying fibromyxoid tumor with prominent collagenous rosettes: Case report with a brief review	4
Single-cell transcriptomes identifies characteristic features of mouse macrophages in liver Mallory-Denk bodies formation	4
The temporal impact of erythropoietin administration on mitochondrial function and dynamics in cardiac ischemia/reperfusion injury	4
MicroRNA-575 acts as a novel oncogene via targeting multiple signaling pathways in glioblastoma	4
Urinary exosomes from patients with diabetic kidney disease induced podocyte apoptosis via microRNA-145-5p/Srgap2 and the RhoA/ROCK pathway	3
Expression profiling of RTL1 in human breast cancer tissues and cell lines	3
Acquired MET amplification in non-small cell lung cancer is highly associated with the exposure of EGFR inhibitors and may not affect patients' outcome	3
WITHDRAWN: MiR-140 suppresses airway inflammation and inhibits bronchial epithelial cell apoptosis in asthma by targeting GSK3β	3
Angiotensin inhibition and cellular senescence in the developing rat kidney	3
Effect of glycated HDL on oxidative stress and cholesterol homeostasis in a human bladder cancer cell line, J82	3
Amplicon-based NGS test for assessing MLH1 promoter methylation and its correlation with BRAF mutation in colorectal cancer patients	3
The role of adipokines in leiomyomas development	3
Predictive value of 4-Hydroxyglutamate and miR-149-5p on eclampsia	3
RAB5A effect on metastasis of hepatocellular carcinoma cell line via altering the pro-invasive content of exosomes	3
Sulfur mustard corneal injury is associated with alterations in the epithelial basement membrane and stromal extracellular matrix	3
A targeted expression panel for classification, gene fusion detection and PD-L1 measurements – Can molecular profiling replace immunohistochemistry in non-small cell lung cancer?	3
Role of plasminogen activator inhibitor-1 in oral tongue squamous cell carcinoma: An immunohistochemical and in vitro analysis	3
Mechanism of autophagy regulating chemoresistance in esophageal cancer cells	3
Cytokeratin 20 expression is linked to stage progression and to poor prognosis in advanced (pT4) urothelial carcinoma of the bladder	3
Application of high-throughput gene sequencing in lymphoma	3
Neurogranin regulates calcium-dependent cardiac hypertrophy	3