European Journal of Pharmacology

Article	Citations
Editorial Board	309
Inclusion of the in-chain sulfur in 3-thiaCTU increases the efficiency of mitochondrial targeting and cell killing by anticancer aryl-urea fatty acids	208
Resveratrol ameliorates cognitive impairment with improvement of gut microbiota, inflammation, neurogenesis, and synaptic proteins in a mouse model of Gulf War Illness	181
Optimizing the structure of repurposed metformin can improve anti-cholinesterase and anti-amyloidogenic effects	133
Trametinib ameliorated Adriamycin-induced podocyte injury by inhibiting METTL3 modified m6A RCAN1 RNA methylation	129
Ginsenoside Rg1 promotes fetal hemoglobin production in vitro: A potential therapeutic avenue for β-thalassemia	97
Heat stroke-induced structural and functional impairments of cognition-relevant brain areas in mice is associated with alpha-7 nicotinic acetylcholine receptors downregulation	86
Inhibition of TRPC3 channels suppresses seizure susceptibility in the genetically-epilepsy prone rats	75
GPR146 regulates pulmonary vascular remodeling by promoting pulmonary artery smooth muscle cell proliferation through 5-lipoxygenase	74
Efficacy of the neurotensin receptor 1 analog PD149163 in modulation of the kidney inflammation: Inhibition of the nuclear factor kappa β signaling pathway and oxidative stress in endotoxemic mice	73
Antidepressants interact with an LPA3 receptor binding site: Functional and docking studies	73
Evodiamine impairs HIF1A histone lactylation to inhibit Sema3A-mediated angiogenesis and PD-L1 by inducing ferroptosis in prostate cancer	73
Calycosin treats acute myocardial infarction via NLRP3 inflammasome: Bioinformatics, network pharmacology and experimental validation	72
The novel GLP-1 / GIP dual agonist DA3-CH is more effective than liraglutide in the MPTP mouse model of Parkinson's disease	66
Molecular mechanism and therapeutic significance of dihydromyricetin in nonalcoholic fatty liver disease	65
Preventive effects of (−) epicatechin on tachycardia, cardiac hypertrophy, and nuclear factor- κB inflammatory signaling pathway in isoproterenol-induced myocardial infarcted rats	65
Nanomedicine: A great boon for cardiac regenerative medicine	64
Sodium channel Nav1.6 involved in modulating isoflurane-induced perioperative cognitive disorder of mice	64
Cyclin-dependent kinase 5 inhibitor attenuates lipopolysaccharide-induced neuroinflammation through metabolic reprogramming	63
Editorial Board	63
Protein detection and localization of the non-selective cation channel TRPC6 in the human heart	63
Editorial Board	63
Ghrelin alleviates placental dysfunction by down-regulating NF-κB phosphorylation in LPS-induced rat model of preeclampsia	62
Risperidone impedes glutamate excitotoxicity in a valproic acid rat model of autism: Role of ADAR2 in AMPA GluA2 RNA editing	60
Integrating network pharmacology, transcriptomics, and molecular simulation to reveal the mechanism of tert-butylhydroquinone for treating diabetic retinopathy	60

Effects of oleanolic acid and ursolic acid on depression-like behaviors induced by maternal separation in mice	58
Corrigendum to “Isopropyl 3-(3, 4-dihydroxyphenyl)-2-hydroxypropanoate protects lipopolysaccharide-induced acute lung injury in mice by attenuating pyroptosis” [Eur. J. Pharmacol. 5 (2023) 175545]	57
Corrigendum to “Guggulsterone inhibits migration and invasion through proteasomal and lysosomal degradation in human glioblastoma cells” [Eur. J. Pharmacol. 938 (2023) 175411]	57
Corrigendum to “AdipoRon ameliorates anxiety- and depression-like behaviors in chronic restraint-stressed mice via AMPK-PPARα-BDNF-TrkB signaling” [Eur. J. Pharmacol. (2026) 1011 178468 doi: 10.1016/j	56
Corrigendum to “Comparison of clopidogrel monotherapy versus prolonged DAPT based on the GRACE score in patients with acute coronary syndromes at High Ischemic and Bleeding Risk: a subgroup analysis o	56
Melittin suppresses aerobic glycolysis by regulating HSF1/PDK3 to increase chemosensitivity of NSCLC	55
Compound Z526 alleviates chemotherapy-induced cachectic muscle loss by ameliorating oxidative stress-driven protein metabolic imbalance and apoptosis	55
Early sacubitril/valsartan therapy reduces ventricular remodeling and cardiac events in patients with acute anterior myocardial infarction	52
Neuroprotective effect of Perillyl alcohol in sporadic Alzheimer's disease in rats	52
Inhibition of intraflagellar transport protein-88 promotes epithelial-to-mesenchymal transition and reduces cardiac remodeling post-myocardial infarction	51
Isorhynchophylline ameliorates the progression of osteoarthritis by inhibiting the NF-κB pathway	50
Suppression of hypoxia-induced CAV1 autophagic degradation enhances nanoalbumin-paclitaxel transcytosis and improves therapeutic activity in pancreatic cancer	49
TNF-alpha mediates airway hyperreactivity in silicotic mice: Effect of thalidomide treatment	48
Dihydromyricetin restores mucus hypersecretion in Air–Liquid interface cultures in COPD by targeting the SRC-MAPK signaling pathway	48
Comprehensive characterization of fatty acid oxidation in triple-negative breast cancer: Focus on biological roles and drug modulation	48
3,3′-O-dimethylquercetin: A bi-functional vasodilator isolated from green propolis of the Caatinga Mimosa tenuiflora	47
Eukaryotic elongation factor 2 kinase inhibitor, A484954 inhibits perivascular sympathetic nerve stimulation-induced vasoconstriction in isolated renal artery	47
Sitagliptin reduces cytokine-induced β-cell apoptosis in prediabetes: A six-month interventional study	46
IL-1 receptor-associated kinase family proteins: An overview of their role in liver disease	46
Phloretin and Enalapril co-administration ameliorates hyperglycemia mediated exacerbation of myocardial injury in rats	45
Arctiin attenuated NASH by inhibiting glycolysis and inflammation via FGFR2/CSF1R signaling	44
Amorphous selenium nanodots alleviate non-alcoholic fatty liver disease via activating VEGF receptor 1 to further inhibit phosphorylation of JNK/p38 MAPK pathways	43
Ameliorative effect of GLP1 agonist on vascular calcification in normoglycemic aged rat aorta via miR34a/SIRT6/NRF2/HO-1 signalling pathway	43
Dopamine agonists versus levodopa monotherapy in early Parkinson's disease for the potential risks of motor complications: A network meta-analysis	43
Hesperetin ameliorates spinal cord injury in rats through suppressing apoptosis, oxidative stress and inflammatory response	43
Extracellular vesicles as multiorgan crosstalk mediators in cardiovascular diseases: emerging biomarkers and therapeutic targets	43
Triple drug co-delivery within nanosystems for synergistic anti-infective, anti-inflammatory, antinociceptive and neuroregenerative therapeutic effects: a focus on pharmacological and nanotechnologica	43
Optimizing dose selection for doxorubicin-induced cardiotoxicity in mice: A comprehensive analysis of single and multiple-dose regimens	42
Neurochemical and behavioral evidence of high abuse liability of 3F-NEB, a novel synthetic cathinone	42
Antagonizing interleukin-5 receptor ameliorates dextran sulfate sodium-induced experimental colitis in mice through reducing NLRP3 inflammasome activation	42
Inhibiting PRMT1 protects against CoNV by regulating macrophages through the FGF2/PI3K/Akt pathway	42
Immunomodulation by systemic administration of exosomes derived from induced pluripotent stem cell mesenchymal stem cells to alleviate liver inflammation and fibrosis in Wilson's disease	42
Corosolic acid attenuates platelet-derived growth factor signaling in macrophages and smooth muscle cells of pulmonary arterial hypertension	41
Intercellular mitochondrial transfer: A novel neuroprotective strategy in stroke management	41
Neuropharmacological insights into artesunate alone and rivastigmine Co-therapy: Synergistic modulation of cognitive impairment in Alzheimer's disease	41
Small molecule CGRP receptor antagonists for the preventive treatment of migraine: A review	40
Autophagic inhibitor ROC-325 ameliorates glomerulosclerosis and podocyte injury via inhibiting autophagic flux in experimental FSGS mice	40
Hydrogen sulfide ameliorates hypertension and vascular dysfunction induced by insulin resistance in rats by reducing oxidative stress and activating eNOS	40
HSP90: A promising target for NSCLC treatments	40
A comprehensive review of targeting RAF kinase in cancer	40
RNAi in psoriasis: A melodic exploration of miRNA, shRNA, and amiRNA with a spotlight on siRNA	40
Significance of NMDA receptor-targeting compounds in neuropsychological disorders: An in-depth review	40
Inverse agonism of lysophospholipids with cationic head groups at Gi-coupled receptor GPR82	39
Corrigendum to “Therapeutic effects of methotrexate encapsulated in hyaluronic acid-coated exosomes derived from Wharton's jelly mesenchymal stem cells in a rat model of rheumatoid arthritis” [Eur. J.	39
Combining brief recall and ketamine treatment prevents stress-primed methamphetamine memory reinstatement via heightening mPFC GABA activity	39
Inhibition of inducible nitric oxide synthase (iNOS) alleviates thoracic aortic aneurysm by regulating mitochondrial dynamics	39
Toward precision dosing of linezolid in critical ill patients: efficiency and risk of thrombocytopenia analysis by population PKPD modeling and simulations	38
Deciphering TGF-β1's role in drug resistance and leveraging plant bioactives for cancer therapy	38
Cardiovascular protective properties of the natural product eugenol	38
The antidiabetic drug teneligliptin induces vasodilation via activation of PKG, Kv channels, and SERCA pumps in aortic smooth muscle	38

Targeting eEF2K induces oxidative stress and sensitizes cancer cells to ferroptosis induction	38
Vanin1 (VNN1) in chronic diseases: Future directions for targeted therapy	38
Validating the temporal performance of genetic biomarkers in an animal model of recurrence/ non-recurrence myocardial infarction persuades by bioinformatics tools	38
Role of 11β-hydroxysteroid dehydrogenase type 1 inhibition in the antiobesity effect of J2H-1702 on adipocytes and a high-fat diet-induced NASH model	38
Tenacissoside H repressed the progression of glioblastoma by inhibiting the PI3K/Akt/mTOR signaling pathway	38
Nitisinone attenuates cartilage degeneration and subchondral osteoclastogenesis in osteoarthritis and concomitantly inhibits the cGAS/STING/NF-κB pathway	37
Inhibition of PKM2 lactylation by geniposide ameliorates synovial hyperplasia in experimental arthritis	37
Small-molecule targeting PKM2 provides a molecular basis of lactylation-dependent fibroblast-like synoviocytes proliferation inhibition against rheumatoid arthritis	37
The mitochondria-gut microbiota crosstalk – A novel frontier in cardiovascular diseases	36
Metformin alleviates glucolipotoxicity-induced pancreatic β cell ferroptosis through regulation of the GPX4/ACSL4 axis	36
The role of arrestin in neurological and neurodegenerative disorders: A systematic review of mechanisms and therapeutic potentials	36
Molecular mechanisms and emerging therapeutics in pulmonary fibrosis: A recent update	36
Novel combinatorial autophagy inhibition therapy for triple negative breast cancers	36
Protective effect of 5,6,7,8-Tetrahydroxyflavone on high altitude cerebral edema in rats	35
Ginsenoside Rb1 promotes the activation of PPARα pathway via inhibiting FADD to ameliorate heart failure	35
Astragaloside IV mitigates cerebral ischaemia-reperfusion injury via inhibition of P62/Keap1/Nrf2 pathway-mediated ferroptosis	35
Advancing health care via artificial intelligence: From concept to clinic	35
Molecular interplay between EIF4 family and circular RNAs in cancer: Mechanisms and therapeutics	35
UC2288 decreases the viability and metastatic activity of human Uveal melanoma cells via activating the AMPK/eIF2/ATF4 ER stress axis	34
Identification of novel SIRT1 up-regulators using a cell-based high-throughput screening assay	34
Orofacial pain models induce impairment in spatial learning and working memory in rodents: A systematic review and meta-analysis	34
Editorial Board	34
Pirfenidone improves voiding function by suppressing bladder fibrosis in underactive bladder rats	34
Editorial Board	34
Alternative role of glucagon-like Peptide-1 receptor agonists in neurodegenerative diseases	34
Face validation and pharmacologic analysis of Sik3 mutant mouse as a possible model of idiopathic hypersomnia	34
Iguratimod suppresses volume-sensitive outwardly rectifying anion channels via arachidonic acid accumulation	34
Alpha1B-adreneroceptor is involved in norepinephrine-induced pulmonary artery smooth muscle cell proliferation via p38 signaling	33
Trigeminal neuropathic pain reduces 50-kHz ultrasonic vocalizations in rats, which are restored by analgesic drugs	33
Targeting the PTCHD1-hippo axis by rhPTH(1-34) restores contact inhibition and suppresses hyperproliferation in psoriatic keratinocytes	33
Manzamine A: A promising marine-derived cancer therapeutic for multi-targeted interactions with E2F8, SIX1, AR, GSK-3β, and V-ATPase - A systematic review	33
Kurarinone induced p53-independent G0/G1 cell cycle arrest by degradation of K-RAS via WDR76 in human colorectal cancer cells	33
Crosstalk between endothelial cells with a non-canonical EndoMT phenotype and cardiomyocytes/fibroblasts via IGFBP5 aggravates TAC-induced cardiac dysfunction	33
Galangin ameliorates osteoarthritis progression by attenuating extracellular matrix degradation in chondrocytes via the activation of PRELP expression	32
Research progress on the role of orphan receptor GPR139 in neuropsychiatric behaviours	32
Tumoral EIF4EBP1 regulates the crosstalk between tumor-associated macrophages and tumor cells in MRTK	32
Sodium nitrite induces tolerance in the mouse aorta: Involvement of the renin-angiotensin system, nitric oxide synthase, and reactive oxygen species	32
Anti-pancreatic lipase and anti-adipogenic effects of 5,7,3′,4′,5′-pentamethoxy and 6,2′,4′-trimethoxy flavone - An in vitro study	32
Recent advancements in targeting the immune system to treat hypertension	32
High-throughput screening of the natural STK11 agonist dauricine: A biphenylisoquinoline alkaloid exerting anti-NSCLC effects and reversing gefitinib resistance	32
Human umbilical cord-derived stem cell sheets improve left ventricular function in rat models of ischemic heart failure	32
Advanced dressings based on novel biological targets for diabetic wound healing: A review	32
Ionic dependency, sensitivity to transport inhibitors and signal transduction of propionate-induced anion secretion in rat caecum	31
Stabilization of mitochondrial function by chlorogenic acid protects against kainic acid-induced seizures and neuronal cell death in rats	31
Hepatitis B Virus X Protein promotes VWF-mediated HCC progression through ST8SIA6-AS1/miR-3150b-3p/ASCL1 axis	31
Dankasterone A induces prostate cancer cell death by inducing oxidative stress	31
Ginkgolide A alleviates cardiac remodeling in mice with myocardial infarction via binding to matrix metalloproteinase-9 to attenuate inflammation	31
SAP30BP aggravates mitochondrial-related ferroptosis in diabetic cardiomyopathy by regulating MFN2-ACSL4 axis	31
CYT997 induces apoptosis in hypertrophic scar fibroblasts and inhibits scar formation	30
Genkwanin blocks the interaction between phosphorylated JNK and NFATc1 to promote osteogenic differentiation and collagen Ⅰ α1 production	30
Curcumin nicotinate decreases serum LDL cholesterol through LDL receptor-mediated mechanism	30
Transcription factor MEOX1 accelerates pulmonary fibrosis by regulating mitophagy and senescence	30
LncRNA DANCR deficiency promotes high glucose-induced endothelial to mesenchymal transition in cardiac microvascular cells via the FoxO1/DDAH1/ADMA signaling pathway	29
Cancer chemotherapy resistance: Mechanisms and recent breakthrough in targeted drug delivery	29
Influence of adrenalectomy on the gut microbiome and MDMA-induced hyperthermia	29
Potential role of remimazolam in alleviating bone cancer pain in mice via modulation of translocator protein in spinal astrocytes	29
Sophoricoside ameliorates cerebral ischemia-reperfusion injury dependent on activating AMPK	29
Essential roles of IL-4 signaling in the prophylactic effect of gardiquimod on chronic stress-induced depression-like behaviors and neuroinflammatory responses	29
Drug repurposing: An emerging strategy in alleviating skin cancer	29
Repositioning of Montelukast to inhibit proliferation of mutated KRAS pancreatic cancer through a novel mechanism that interfere the binding between KRAS and GTP/GDP	29
Effects of cannabinoid agonists and antagonists in male rats discriminating the synthetic cannabinoid AM2201	29
Diosmetin improves myocardial ischemia/reperfusion injury via activation of the SIRT1/NRF2 axis	29
The nanobody Nb.C1 potentiates human acid-sensing ion channel 1a and 1b	29
Ginsenoside Rd attenuates myocardial ischemia injury through improving mitochondrial biogenesis via WNT5A/Ca2+ pathways	29
Demyelination in cuprizone mice is ameliorated by calycosin mediated through astrocyte Nrf2 signaling pathway	29
Astragaloside IV protects against C/EBP homologous protein-mediated apoptosis in oxidized low-density lipoprotein-treated macrophages by promoting autophagy	29
Sodium houttuyfonate protects against cardiac injury by regulating cardiac energy metabolism in diabetic rats	29
A novel Toll-like receptor 7/8–specific antagonist E6742 ameliorates clinically relevant disease parameters in murine models of lupus	29
Next generation Bruton's tyrosine kinase inhibitors – characterization of in vitro potency and selectivity	28
Coixol attenuates osteoclastogenesis and ovariectomy-induced bone loss via the HIF-1α-mediated suppression of NF-κB signaling	28
Hypoxia activates GPR146 which participates in pulmonary vascular remodeling by promoting pyroptosis of pulmonary artery endothelial cells	28
Salidroside attenuates high altitude hypobaric hypoxia-induced brain injury in mice via inhibiting NF-κB/NLRP3 pathway	28
LRP1 at the crossroads of Parkinson's and Alzheimer's: Divergent roles in α-synuclein and amyloid pathology	28
Up-regulated ITGB4 promotes hepatocellular carcinoma metastasis by activating hypoxia-mediated glycolysis and cancer-associated fibroblasts	28
TAK-242 alleviates neuroinflammation and poststroke cognitive impairment by targeting the TLR4/SYK/NF-κB pathway in a cerebral ischemia/reperfusion rat model	28
Cycloheptylprodigiosin from marine bacterium Spartinivicinus ruber MCCC 1K03745T induces a novel form of cell death characterized by Golgi disruption and enhanced secretion of cathepsin D in non-small	28
Trilobatin alleviates non-alcoholic fatty liver disease in high-fat diet plus streptozotocin-induced diabetic mice by suppressing NLRP3 inflammasome activation	28
Teneligliptin, a DPP4 inhibitor protects dopaminergic neurons in PD models via inhibiting of oxidative stress and ferroptosis	28
Pirfenidone and nintedanib attenuates pulmonary artery endothelial and smooth muscle cells transformations induced by IL-11	28
Targeting endothelial cells: A novel strategy for pulmonary fibrosis treatment	28

SGLT2 inhibitor dapagliflozin mitigates skeletal muscle pathology by modulating key proteins involved in glucose and ion homeostasis in an animal model of heart failure	28
Effects of the serotonin 5-HT1B receptor agonist CP 94253 on the locomotor activity and body temperature of preweanling and adult male and female rats	27
Sustained AT1R stimulation induces upregulation of growth factors in human cardiac fibroblasts via Gαq/TGF-β/ERK signaling that influences myocyte hypertrophy	27
Neuroprotective effect of crocetin against epileptiform activity induced by microinjection of penicillin into the somatosensory cortex of the brain: Role of GABAA-benzodiazepine receptor, oxidative st	27
The key roles of non-coding RNAs in the pathophysiology of hypertension	27
Targets, trials and tribulations in Alzheimer therapeutics	27
Pharmacologic deprivation of serum inorganic phosphate ameliorates renal fibrosis via the modulation of systemic inflammation	27
Lapatinib ditosylate rescues motor deficits in rotenone-intoxicated rats: Potential repurposing of anti-cancer drug as a disease-modifying agent in Parkinson's disease	27
Succinate level is increased and succinate dehydrogenase exerts forward and reverse catalytic activities in lipopolysaccharides-stimulated cardiac tissue: The protective role of dimethyl malonate	27
A BET inhibitor, NHWD-870, can downregulate dendritic cells maturation via the IRF7-mediated signaling pathway to ameliorate imiquimod-induced psoriasis-like murine skin inflammation	27
Asperosaponin VI alleviates intervertebral disc degeneration by suppressing nucleus pulposus cell pyroptosis through modulation of the NF-κB/NLRP3 signaling pathway	27
PARPs in tumor immunology: Signal transduction and combination therapy for the future	27
Dihydrotanshinone I improves cardiac function by promoting lymphangiogenesis after myocardial ischemia-reperfusion injury	27
Involvement of ferroptosis in eribulin-induced cytotoxicity in ovarian clear cell carcinoma	27
Hypoxia-inducible factor-1: Regulatory mechanisms and drug therapy in myocardial infarction	26
Diazepam-induced locomotor sensitization and increased cell surface AMPA receptors: Involvement of GABAA α1 subunit	26
Dopamine agonist pramipexole halts leflunomide nephrotoxicity: A dual strike on TLR4-Driven inflammation and PI3K/Akt suppression	26
Tryptanthrin impairs platelet function and thrombus formation by reducing Gp1bα expression	26
Amelioration of D-galactose-induced hyposalivation in aging rats by the GLP-1 receptor agonist Exendin-4	26
Exploring the role of cathelicidin LL-37 and ceragenins in wound healing processes	26
Recent trends in diabetic wound healing with nanofibrous scaffolds	26
Cancer-associated fibroblasts (CAFs) and tumor-associated macrophages (TAMs); where do they stand in tumorigenesis and how they can change the face of cancer therapy?	26
Desmopressin enhances random-pattern skin flap survival in rats: Possible role of vasopressin Type-1a and 2 receptors	25
Therapeutic effects of finerenone and exenatide on diabetes-induced heart failure: A combined approach targeting inflammation and oxidative stress	25
Betulinic acid abates age-related kidney structural changes and proteinuria by contending oxidative stress in male rats	25
Comparative efficacy and acceptability of drug treatments for Parkinson’s disease with depression: A systematic review with network meta-analysis	25
Mutation of valine 53 at the interface between extracellular and transmembrane domains of the β2 principal subunit affects the GABAA receptor gating	25
Pregabalin can interact synergistically with Kv7 channel openers to exert antinociception in mice	25
Investigation of the effects of losartan and captopril on rotenone-induced inflammation via TLR4/NLRP3 pathway: An integrative in vitro and in silico study	25
The next frontier in multiple sclerosis therapies: Current advances and evolving targets	25
Transcription factor EB protects against endoplasmic reticulum stress in human coronary artery endothelial cells	25
LncRNAS—modulators of neurovascular units in diabetic retinopathy	25
Metabolic reprogramming of glutamine involved in tumorigenesis, multidrug resistance and tumor immunity	25
Oncolytic viruses as emerging therapy against cancers including Oncovirus-induced cancers	25
Aucubin supplementation alleviate diabetes induced-disruption of blood-testis barrier and testicular damage via stabilizing cell junction integrity	25
Editorial Board	25
Editorial Board	25
Ankrd1 regulates endogenous cardiac regeneration in mice by modulating cyclin D1	25
Potential of Orlistat to induce apoptotic and antiangiogenic effects as well as inhibition of fatty acid synthesis in breast cancer cells	25
Biochanin A inhibits excitotoxicity-triggered ferroptosis in hippocampal neurons	25
Astragalus polysaccharide attenuates bleomycin-induced pulmonary fibrosis by inhibiting TLR4/ NF-κB signaling pathway and regulating gut microbiota	25
In vivo and In vitro Crosstalk Among CBD, Aβ, and endocannabinoid system enzymes and receptors	25
Molsidomine ameliorates DEXA-induced insulin resistance: Involvement of HMGB1/JAK1/STAT3 signaling pathway	24
Immunomodulatory role of Nanocurcumin in COVID-19 patients with dropped natural killer cells frequency and function	24
(R)-Bambuterol attenuates DSS-induced chronic colitis by suppressing inflammation, repairing intestinal barrier, and modulating gut microbiota and serum metabolomic profile	24
Therapeutic potency of marine collagen/pectin scaffolds - Fabrication, characterization and evaluation	24
Integrated network pharmacology and molecular docking analyses of the mechanisms underlying the antihypertensive effects of lotusine	24
The endocrine disruptor vinclozolin causes endothelial injury via eNOS/Nox4/IRE1α signaling	24
Synthesis of 2-(2-(4-thioxo-3H-1,2-dithiole-5-yl) phenoxy)ethyl)isoindole-1,3-thione, a novel hydrogen sulfide-releasing phthalimide hybrid, and evaluation of its activity in models of inflammatory pa	24
Inhibiting 5-HT2C receptor in the hippocampus rescues EphB2-dependent memory impairment in mice	24
Omega-3 fatty acids prevent nicotine withdrawal-induced exacerbation of anxiety and depression by affecting oxidative stress balance, inflammatory response, BDNF and serotonin metabolism in rats	24
Effect of hyperoside on osteoporosis in ovariectomized mice through estrogen receptor α/ITGβ3 signaling pathway	24
Functional studies and molecular dynamics reveal BPP-BrachyNH2-induced relaxation in male rat small mesenteric arteries via binding to argininosuccinate synthase	23
Catalyzing biopharma leaders: Sparking innovative medicines through inclusive engagement	23
Protective effects of atorvastatin on testicular dysfunction and reduced sperm quality induced by high-fat diet in mice: The inhibitory mechanism of oxidative stress	23
Hinokitiol protects gastric injury from ethanol exposure via its iron sequestration capacity	23
Sappanone A ameliorated imiquimod-induced psoriasis-like dermatitis in BALB/c mice via suppressing Mmp8 expression and IL-17 signaling pathway	23
Retraction notice to “Apoptotic cell death: A possible key event in mediating the in vitro anti-proliferative effect of a novel copper(II) complex, [Cu(4-Mecdoa) (phen)2] (phen = phenanthroline, 4-Mec	23
Anticancer activity and metabolic alteration in colon and prostate cancer cells by novel moxifloxacin conjugates with fatty acids	23
Establishment of a murine chronic proximal thoracic aortic aneurysm model by combining periaortic elastase application with oral BAPN administration	23
Escaping a second time round: A replication and extension study on the motivational climate of and knowledge gain in a general pharmacology course	23
Harringtonine metabolites: 5'-de-O-methylharringtonine and cephalotaxine, targeting spike protein and TMPRSS2 to double block membrane fusion of SARS-CoV-2 and its variants	23
The soluble guanylate cyclase (sGC) stimulator vericiguat inhibits platelet activation and thrombosis	23
Corrigendum to “Combination therapy with citalopram, bupropion, and lithium for the amelioration of the depressive-related effects induced by dexamethasone in male mice” [Eur. J. Pharmacol. 1002 (2025	23
Synthetic flavokawain analog (E)-1-(2′-hydroxy-4′,6′-dimethoxyphenyl)-3-(3-methoxy-4-(3-morpholinopropoxy)phenyl)prop-2-en-1-one (FK-morph) effectively regresses endometriotic implants in rats	23
Discovery of cinnamoyl–flavonoid hybrid derivatives as inhibitors of SARS-CoV-2 Mpro and anti-inflammatory agents: Experimental and in silico insights into their efficacy against lipopolysaccharide-in	23
Michael acceptor-dependent pro-oxidative intervention against angiogenesis by [6]-dehydroshogaol, a pungent constituent of ginger	23
Comparison of the effects of peficitinib and tofacitinib in the adjuvant-induced arthritis rat model	23
New insights on the differential interaction of sulfiredoxin with members of the peroxiredoxin family revealed by protein-protein docking and experimental studies	23
Targeting TRPs in autophagy regulation and human diseases	23
GW501516 facilitated tumor immune escape by inhibiting phagocytosis	23
Epac as a tractable therapeutic target	23
Biopharmaceuticals against substance use disorders – Present and future	23
Phosphatidic acid as a cofactor of mTORC1 in platinum-based chemoresistance: Mechanisms and therapeutic potential	22
Bombesin improves visceral hypersensitivity and colonic hyperpermeability via BB1 receptor–dependent multi-pathway mechanisms in a rat model of irritable bowel syndrome	22
FGF17 protects cerebral ischemia reperfusion-induced blood-brain barrier disruption via FGF receptor 3-mediated PI3K/AKT signaling pathway	22
Analysis of differences in dupilumab-associated adverse drug event signals between children and adults based on the FAERS database	22
Fumarate and its downstream signalling pathways in the cardiorenal system: Recent insights and novel expositions in the etiology of hypertension	22
Complementary effects of dapagliflozin and lobeglitazone on metabolism in a diet-induced obese mouse model	22
Dehydrozingerone alleviates pulmonary fibrosis via inhibition of inflammation and epithelial-mesenchymal transition by regulating the Wnt/β-catenin pathway	22
Effects of decrease in Klotho protein expression on insulin signaling and levels of proteins related to brain energy metabolism	22
Uncovering the pleiotropic effects of oleoylethanolamide on obesity-driven chronic kidney disease in mice	22
Cordycepin deteriorates 5’ fluorouracil-induced anaemia by AMPK activation	22
Exploring Anticholinergic and anti-amnesic potential of methyl substituted monocarbonyl curcumin derivatives	22
Koumine alters immune barrier function by targeting TGFβ-mediated collagen deposition in gastric cancer	22
Imperatorin attenuates CCl4-induced cirrhosis and portal hypertension by improving vascular remodeling and profibrogenic pathways	22
Mutational effects of the asparagine198 and glutamate223 residues on the human norepinephrine transporter on basal and HIV-1 Tat protein-induced inhibition of dopamine transport	22
Combination therapy with cetirizine and anti-PD-1 antibody suppresses colitis-induced colon tumor formation in mice	22
Curcumol suppresses endothelial-to-mesenchymal transition via inhibiting the AKT/GSK3β signaling pathway and alleviates pulmonary arterial hypertension in rats	22
Inhibition of MALT1 reduces ferroptosis in rat hearts following ischemia/reperfusion via enhancing the Nrf2/SLC7A11 pathway	22
Cuproptosis induced by curcumin interfering with proliferation and energy metabolism in colorectal cancer: 3D tumor model and computational simulations reveal curcumin inhibition of HSPD1 and CALCOCO2	22
Diosgenin inhibits prostate cancer progression by inducing UHRF1 protein degradation	22
Luteolin alleviates hyposalivation by upregulating AQP5 through binding to estrogen receptor β and potentiating the saliva secretion signaling pathway	22
A positive allosteric modulator of α7 nicotinic receptor reduces levodopa-induced dyskinesias in hemi-parkinsonian mice	22
Melatonin suppresses cellular senescence in diabetic kidney disease though the Wnt/β-catenin signaling pathway	22