European Journal of Pharmacology

Article	Citations
Editorial Board	261
Corrigendum to “Isopropyl 3-(3, 4-dihydroxyphenyl)-2-hydroxypropanoate protects lipopolysaccharide-induced acute lung injury in mice by attenuating pyroptosis” [Eur. J. Pharmacol. 5 (2023) 175545]	166
Combining brief recall and ketamine treatment prevents stress-primed methamphetamine memory reinstatement via heightening mPFC GABA activity	134
Suppression of hypoxia-induced CAV1 autophagic degradation enhances nanoalbumin-paclitaxel transcytosis and improves therapeutic activity in pancreatic cancer	131
Inclusion of the in-chain sulfur in 3-thiaCTU increases the efficiency of mitochondrial targeting and cell killing by anticancer aryl-urea fatty acids	116
Molecular mechanism and therapeutic significance of dihydromyricetin in nonalcoholic fatty liver disease	108
Cardiovascular protective properties of the natural product eugenol	105
Resveratrol ameliorates cognitive impairment with improvement of gut microbiota, inflammation, neurogenesis, and synaptic proteins in a mouse model of Gulf War Illness	90
Optimizing the structure of repurposed metformin can improve anti-cholinesterase and anti-amyloidogenic effects	86
Trametinib ameliorated Adriamycin-induced podocyte injury by inhibiting METTL3 modified m6A RCAN1 RNA methylation	78
Ginsenoside Rg1 promotes fetal hemoglobin production in vitro: A potential therapeutic avenue for β-thalassemia	76
Inverse agonism of lysophospholipids with cationic head groups at Gi-coupled receptor GPR82	74
Molecular interplay between EIF4 family and circular RNAs in cancer: Mechanisms and therapeutics	71
Calycosin treats acute myocardial infarction via NLRP3 inflammasome: Bioinformatics, network pharmacology and experimental validation	70
Novel combinatorial autophagy inhibition therapy for triple negative breast cancers	70
Editorial Board	65
Extracellular vesicles as multiorgan crosstalk mediators in cardiovascular diseases: emerging biomarkers and therapeutic targets	65
Corrigendum to “Guggulsterone inhibits migration and invasion through proteasomal and lysosomal degradation in human glioblastoma cells” [Eur. J. Pharmacol. 938 (2023) 175411]	61
Protein detection and localization of the non-selective cation channel TRPC6 in the human heart	59
Editorial Board	59
RNAi in psoriasis: A melodic exploration of miRNA, shRNA, and amiRNA with a spotlight on siRNA	57
Validating the temporal performance of genetic biomarkers in an animal model of recurrence/ non-recurrence myocardial infarction persuades by bioinformatics tools	57
Cyclin-dependent kinase 5 inhibitor attenuates lipopolysaccharide-induced neuroinflammation through metabolic reprogramming	56
Orofacial pain models induce impairment in spatial learning and working memory in rodents: A systematic review and meta-analysis	56
Characterisation of bis(4-aminoquinoline)s as α1A adrenoceptor allosteric modulators	55

Amorphous selenium nanodots alleviate non-alcoholic fatty liver disease via activating VEGF receptor 1 to further inhibit phosphorylation of JNK/p38 MAPK pathways	55
Inhibiting PRMT1 protects against CoNV by regulating macrophages through the FGF2/PI3K/Akt pathway	55
Inhibition of TRPC3 channels suppresses seizure susceptibility in the genetically-epilepsy prone rats	54
Ghrelin alleviates placental dysfunction by down-regulating NF-κB phosphorylation in LPS-induced rat model of preeclampsia	54
Role of 11β-hydroxysteroid dehydrogenase type 1 inhibition in the antiobesity effect of J2H-1702 on adipocytes and a high-fat diet-induced NASH model	54
Long non-coding RNA MALAT1 modulates myocardial ischemia-reperfusion injury through the PI3K/Akt/eNOS pathway by sponging miRNA-133a-3p to target IGF1R expression	54
Targeting eEF2K induces oxidative stress and sensitizes cancer cells to ferroptosis induction	53
Inhibition of inducible nitric oxide synthase (iNOS) alleviates thoracic aortic aneurysm by regulating mitochondrial dynamics	52
Neuroprotective effect of Perillyl alcohol in sporadic Alzheimer's disease in rats	52
Deciphering TGF-β1's role in drug resistance and leveraging plant bioactives for cancer therapy	52
Eukaryotic elongation factor 2 kinase inhibitor, A484954 inhibits perivascular sympathetic nerve stimulation-induced vasoconstriction in isolated renal artery	51
3,3′-O-dimethylquercetin: A bi-functional vasodilator isolated from green propolis of the Caatinga Mimosa tenuiflora	50
Corrigendum to “Comparison of clopidogrel monotherapy versus prolonged DAPT based on the GRACE score in patients with acute coronary syndromes at High Ischemic and Bleeding Risk: a subgroup analysis o	50
Phloretin and Enalapril co-administration ameliorates hyperglycemia mediated exacerbation of myocardial injury in rats	49
Integrating network pharmacology, transcriptomics, and molecular simulation to reveal the mechanism of tert-butylhydroquinone for treating diabetic retinopathy	48
Inhibition of intraflagellar transport protein-88 promotes epithelial-to-mesenchymal transition and reduces cardiac remodeling post-myocardial infarction	47
Significance of NMDA receptor-targeting compounds in neuropsychological disorders: An in-depth review	46
Advancing health care via artificial intelligence: From concept to clinic	46
Early sacubitril/valsartan therapy reduces ventricular remodeling and cardiac events in patients with acute anterior myocardial infarction	46
IL-1 receptor-associated kinase family proteins: An overview of their role in liver disease	46
Sitagliptin reduces cytokine-induced β-cell apoptosis in prediabetes: A six-month interventional study	45
HSP90: A promising target for NSCLC treatments	44
Hesperetin ameliorates spinal cord injury in rats through suppressing apoptosis, oxidative stress and inflammatory response	44
Metformin alleviates glucolipotoxicity-induced pancreatic β cell ferroptosis through regulation of the GPX4/ACSL4 axis	44
Ameliorative effect of GLP1 agonist on vascular calcification in normoglycemic aged rat aorta via miR34a/SIRT6/NRF2/HO-1 signalling pathway	43
The antidiabetic drug teneligliptin induces vasodilation via activation of PKG, Kv channels, and SERCA pumps in aortic smooth muscle	43
Small-molecule targeting PKM2 provides a molecular basis of lactylation-dependent fibroblast-like synoviocytes proliferation inhibition against rheumatoid arthritis	43
Autophagic inhibitor ROC-325 ameliorates glomerulosclerosis and podocyte injury via inhibiting autophagic flux in experimental FSGS mice	42
Dihydromyricetin restores mucus hypersecretion in Air–Liquid interface cultures in COPD by targeting the SRC-MAPK signaling pathway	42
Effects of chronic mirabegron treatment on metabolic and cardiovascular parameters as well as on atherosclerotic lesions of WHHL rabbits with high-fructose high-fat diet-induced insulin resistance.	42
The novel GLP-1 / GIP dual agonist DA3-CH is more effective than liraglutide in the MPTP mouse model of Parkinson's disease	41
Risperidone impedes glutamate excitotoxicity in a valproic acid rat model of autism: Role of ADAR2 in AMPA GluA2 RNA editing	41
TNF-alpha mediates airway hyperreactivity in silicotic mice: Effect of thalidomide treatment	41
Vanin1 (VNN1) in chronic diseases: Future directions for targeted therapy	40
The role of arrestin in neurological and neurodegenerative disorders: A systematic review of mechanisms and therapeutic potentials	40
Efficacy of the neurotensin receptor 1 analog PD149163 in modulation of the kidney inflammation: Inhibition of the nuclear factor kappa β signaling pathway and oxidative stress in endotoxemic mice	40
Comprehensive characterization of fatty acid oxidation in triple-negative breast cancer: Focus on biological roles and drug modulation	39
Neuropharmacological insights into artesunate alone and rivastigmine Co-therapy: Synergistic modulation of cognitive impairment in Alzheimer's disease	39
Corosolic acid attenuates platelet-derived growth factor signaling in macrophages and smooth muscle cells of pulmonary arterial hypertension	39
Intercellular mitochondrial transfer: A novel neuroprotective strategy in stroke management	39
Hydrogen sulfide ameliorates hypertension and vascular dysfunction induced by insulin resistance in rats by reducing oxidative stress and activating eNOS	38
Small molecule CGRP receptor antagonists for the preventive treatment of migraine: A review	38
Preventive effects of (−) epicatechin on tachycardia, cardiac hypertrophy, and nuclear factor- κB inflammatory signaling pathway in isoproterenol-induced myocardial infarcted rats	38
Effects of oleanolic acid and ursolic acid on depression-like behaviors induced by maternal separation in mice	37
Isorhynchophylline ameliorates the progression of osteoarthritis by inhibiting the NF-κB pathway	37
Protective effect of 5,6,7,8-Tetrahydroxyflavone on high altitude cerebral edema in rats	37
Ginsenoside Rb1 promotes the activation of PPARα pathway via inhibiting FADD to ameliorate heart failure	37
Toward precision dosing of linezolid in critical ill patients: efficiency and risk of thrombocytopenia analysis by population PKPD modeling and simulations	37
The mitochondria-gut microbiota crosstalk – A novel frontier in cardiovascular diseases	37
A comprehensive review of targeting RAF kinase in cancer	36

Nanomedicine: A great boon for cardiac regenerative medicine	36
Compound Z526 alleviates chemotherapy-induced cachectic muscle loss by ameliorating oxidative stress-driven protein metabolic imbalance and apoptosis	36
Molecular mechanisms and emerging therapeutics in pulmonary fibrosis: A recent update	36
Astragaloside IV mitigates cerebral ischaemia-reperfusion injury via inhibition of P62/Keap1/Nrf2 pathway-mediated ferroptosis	35
Antagonizing interleukin-5 receptor ameliorates dextran sulfate sodium-induced experimental colitis in mice through reducing NLRP3 inflammasome activation	35
GPR146 regulates pulmonary vascular remodeling by promoting pulmonary artery smooth muscle cell proliferation through 5-lipoxygenase	35
Arctiin attenuated NASH by inhibiting glycolysis and inflammation via FGFR2/CSF1R signaling	35
Corrigendum to “AdipoRon ameliorates anxiety- and depression-like behaviors in chronic restraint-stressed mice via AMPK-PPARα-BDNF-TrkB signaling” [Eur. J. Pharmacol. (2026) 1011 178468 doi: 10.1016/j	35
Editorial Board	34
Editorial Board	34
Tenacissoside H repressed the progression of glioblastoma by inhibiting the PI3K/Akt/mTOR signaling pathway	34
Nitisinone attenuates cartilage degeneration and subchondral osteoclastogenesis in osteoarthritis and concomitantly inhibits the cGAS/STING/NF-κB pathway	34
Evodiamine impairs HIF1A histone lactylation to inhibit Sema3A-mediated angiogenesis and PD-L1 by inducing ferroptosis in prostate cancer	34
Dopamine agonists versus levodopa monotherapy in early Parkinson's disease for the potential risks of motor complications: A network meta-analysis	34
Suppression of hippocampal GABAergic transmission impairs memory in rodent models of Alzheimer's disease	34
Optimizing dose selection for doxorubicin-induced cardiotoxicity in mice: A comprehensive analysis of single and multiple-dose regimens	34
Manzamine A: A promising marine-derived cancer therapeutic for multi-targeted interactions with E2F8, SIX1, AR, GSK-3β, and V-ATPase - A systematic review	34
Melittin suppresses aerobic glycolysis by regulating HSF1/PDK3 to increase chemosensitivity of NSCLC	34
Sodium nitrite induces tolerance in the mouse aorta: Involvement of the renin-angiotensin system, nitric oxide synthase, and reactive oxygen species	33
Editorial Board	33
Tumoral EIF4EBP1 regulates the crosstalk between tumor-associated macrophages and tumor cells in MRTK	33
SGLT2 inhibitor dapagliflozin mitigates skeletal muscle pathology by modulating key proteins involved in glucose and ion homeostasis in an animal model of heart failure	33
Protective effects of 5(S)-5-carboxystrictosidine on myocardial ischemia-reperfusion injury through activation of mitochondrial KATP channels	33
Teneligliptin, a DPP4 inhibitor protects dopaminergic neurons in PD models via inhibiting of oxidative stress and ferroptosis	33
Tryptanthrin impairs platelet function and thrombus formation by reducing Gp1bα expression	33
Corrigendum to “Protective effects of cortex fraxini coumarines against oxonate-induced hyperuricemia and renal dysfunction in mice” [Eur. J. Pharmacol. 666 (2011) 196–204]	33
Alpha1B-adreneroceptor is involved in norepinephrine-induced pulmonary artery smooth muscle cell proliferation via p38 signaling	32
Human umbilical cord-derived stem cell sheets improve left ventricular function in rat models of ischemic heart failure	32
Next generation Bruton's tyrosine kinase inhibitors – characterization of in vitro potency and selectivity	32
High-throughput screening of the natural STK11 agonist dauricine: A biphenylisoquinoline alkaloid exerting anti-NSCLC effects and reversing gefitinib resistance	32
Targets, trials and tribulations in Alzheimer therapeutics	32
Anti-pancreatic lipase and anti-adipogenic effects of 5,7,3′,4′,5′-pentamethoxy and 6,2′,4′-trimethoxy flavone - An in vitro study	32
LncRNAS—modulators of neurovascular units in diabetic retinopathy	32
Biochanin A inhibits excitotoxicity-triggered ferroptosis in hippocampal neurons	32
Crosstalk between endothelial cells with a non-canonical EndoMT phenotype and cardiomyocytes/fibroblasts via IGFBP5 aggravates TAC-induced cardiac dysfunction	31
Diazepam-induced locomotor sensitization and increased cell surface AMPA receptors: Involvement of GABAA α1 subunit	31
Pirfenidone and nintedanib attenuates pulmonary artery endothelial and smooth muscle cells transformations induced by IL-11	31
Identification of novel SIRT1 up-regulators using a cell-based high-throughput screening assay	31
Genkwanin blocks the interaction between phosphorylated JNK and NFATc1 to promote osteogenic differentiation and collagen Ⅰ α1 production	31
Aucubin supplementation alleviate diabetes induced-disruption of blood-testis barrier and testicular damage via stabilizing cell junction integrity	31
Transcription factor EB protects against endoplasmic reticulum stress in human coronary artery endothelial cells	31
Cycloheptylprodigiosin from marine bacterium Spartinivicinus ruber MCCC 1K03745T induces a novel form of cell death characterized by Golgi disruption and enhanced secretion of cathepsin D in non-small	31
Potential role of remimazolam in alleviating bone cancer pain in mice via modulation of translocator protein in spinal astrocytes	31
Transcription factor MEOX1 accelerates pulmonary fibrosis by regulating mitophagy and senescence	31
CRISPR/Cas9-based multiplex genome editing of BCL11A and HBG efficiently induces fetal hemoglobin expression	31
Hypoxia activates GPR146 which participates in pulmonary vascular remodeling by promoting pyroptosis of pulmonary artery endothelial cells	31
Trigeminal neuropathic pain reduces 50-kHz ultrasonic vocalizations in rats, which are restored by analgesic drugs	31
CYT997 induces apoptosis in hypertrophic scar fibroblasts and inhibits scar formation	31
Research progress on the role of orphan receptor GPR139 in neuropsychiatric behaviours	30
Effects of intranasal azithromycin on features of cigarette smoke-induced lung inflammation	30
Succinate level is increased and succinate dehydrogenase exerts forward and reverse catalytic activities in lipopolysaccharides-stimulated cardiac tissue: The protective role of dimethyl malonate	30
Recent advancements in targeting the immune system to treat hypertension	30
Galangin ameliorates osteoarthritis progression by attenuating extracellular matrix degradation in chondrocytes via the activation of PRELP expression	30
Dankasterone A induces prostate cancer cell death by inducing oxidative stress	30
Ankrd1 regulates endogenous cardiac regeneration in mice by modulating cyclin D1	30
Poncirin ameliorates cardiac ischemia-reperfusion injury by activating PI3K/AKT/PGC-1α signaling	30
Metabolic reprogramming of glutamine involved in tumorigenesis, multidrug resistance and tumor immunity	30
Targeting endothelial cells: A novel strategy for pulmonary fibrosis treatment	30
Curcumin nicotinate decreases serum LDL cholesterol through LDL receptor-mediated mechanism	30
Demyelination in cuprizone mice is ameliorated by calycosin mediated through astrocyte Nrf2 signaling pathway	30
Influence of adrenalectomy on the gut microbiome and MDMA-induced hyperthermia	30
A BET inhibitor, NHWD-870, can downregulate dendritic cells maturation via the IRF7-mediated signaling pathway to ameliorate imiquimod-induced psoriasis-like murine skin inflammation	29
Repositioning of Montelukast to inhibit proliferation of mutated KRAS pancreatic cancer through a novel mechanism that interfere the binding between KRAS and GTP/GDP	29
Antidepressant-like effect of sodium orthovanadate in a mouse model of chronic unpredictable mild stress	29
Dihydrotanshinone I improves cardiac function by promoting lymphangiogenesis after myocardial ischemia-reperfusion injury	29
Effects of cannabinoid agonists and antagonists in male rats discriminating the synthetic cannabinoid AM2201	29
A novel Toll-like receptor 7/8–specific antagonist E6742 ameliorates clinically relevant disease parameters in murine models of lupus	29
LncRNA DANCR deficiency promotes high glucose-induced endothelial to mesenchymal transition in cardiac microvascular cells via the FoxO1/DDAH1/ADMA signaling pathway	28
Involvement of ferroptosis in eribulin-induced cytotoxicity in ovarian clear cell carcinoma	28
Pirfenidone improves voiding function by suppressing bladder fibrosis in underactive bladder rats	28
Trilobatin alleviates non-alcoholic fatty liver disease in high-fat diet plus streptozotocin-induced diabetic mice by suppressing NLRP3 inflammasome activation	28
Comparative efficacy and acceptability of drug treatments for Parkinson’s disease with depression: A systematic review with network meta-analysis	28
Oncolytic viruses as emerging therapy against cancers including Oncovirus-induced cancers	28
Lapatinib ditosylate rescues motor deficits in rotenone-intoxicated rats: Potential repurposing of anti-cancer drug as a disease-modifying agent in Parkinson's disease	28
LRP1 at the crossroads of Parkinson's and Alzheimer's: Divergent roles in α-synuclein and amyloid pathology	28
Hypoxia-inducible factor-1: Regulatory mechanisms and drug therapy in myocardial infarction	28
Hepatitis B Virus X Protein promotes VWF-mediated HCC progression through ST8SIA6-AS1/miR-3150b-3p/ASCL1 axis	28
Asperosaponin VI alleviates intervertebral disc degeneration by suppressing nucleus pulposus cell pyroptosis through modulation of the NF-κB/NLRP3 signaling pathway	27
Up-regulated ITGB4 promotes hepatocellular carcinoma metastasis by activating hypoxia-mediated glycolysis and cancer-associated fibroblasts	27
Astragaloside IV protects against C/EBP homologous protein-mediated apoptosis in oxidized low-density lipoprotein-treated macrophages by promoting autophagy	27

Drug repurposing: An emerging strategy in alleviating skin cancer	27
The key roles of non-coding RNAs in the pathophysiology of hypertension	27
Advanced dressings based on novel biological targets for diabetic wound healing: A review	26
Inhibition of abnormally activated HIF-1α-GLUT1/3-glycolysis pathway enhances the sensitivity of hepatocellular carcinoma to 5-caffeoylquinic acid and its derivatives	26
Pharmacologic deprivation of serum inorganic phosphate ameliorates renal fibrosis via the modulation of systemic inflammation	26
Ginsenoside Rd attenuates myocardial ischemia injury through improving mitochondrial biogenesis via WNT5A/Ca2+ pathways	26
Potential of Orlistat to induce apoptotic and antiangiogenic effects as well as inhibition of fatty acid synthesis in breast cancer cells	26
Pregabalin can interact synergistically with Kv7 channel openers to exert antinociception in mice	26
Face validation and pharmacologic analysis of Sik3 mutant mouse as a possible model of idiopathic hypersomnia	26
PARPs in tumor immunology: Signal transduction and combination therapy for the future	26
Mutation of valine 53 at the interface between extracellular and transmembrane domains of the β2 principal subunit affects the GABAA receptor gating	26
Salidroside attenuates high altitude hypobaric hypoxia-induced brain injury in mice via inhibiting NF-κB/NLRP3 pathway	26
Effects of the serotonin 5-HT1B receptor agonist CP 94253 on the locomotor activity and body temperature of preweanling and adult male and female rats	26
Stabilization of mitochondrial function by chlorogenic acid protects against kainic acid-induced seizures and neuronal cell death in rats	26
Neuroprotective effect of crocetin against epileptiform activity induced by microinjection of penicillin into the somatosensory cortex of the brain: Role of GABAA-benzodiazepine receptor, oxidative st	26
Cancer-associated fibroblasts (CAFs) and tumor-associated macrophages (TAMs); where do they stand in tumorigenesis and how they can change the face of cancer therapy?	26
Dopamine agonist pramipexole halts leflunomide nephrotoxicity: A dual strike on TLR4-Driven inflammation and PI3K/Akt suppression	26
Cancer chemotherapy resistance: Mechanisms and recent breakthrough in targeted drug delivery	25
Inhibition of CHIT1 as a novel therapeutic approach in idiopathic pulmonary fibrosis	25
Alternative role of glucagon-like Peptide-1 receptor agonists in neurodegenerative diseases	25
Astragalus polysaccharide attenuates bleomycin-induced pulmonary fibrosis by inhibiting TLR4/ NF-κB signaling pathway and regulating gut microbiota	25
Naproxen as a potential candidate for promoting rivastigmine anti-Alzheimer activity against aluminum chloride-prompted Alzheimer's-like disease in rats; neurogenesis and apoptosis modulation as a pos	25
Sustained AT1R stimulation induces upregulation of growth factors in human cardiac fibroblasts via Gαq/TGF-β/ERK signaling that influences myocyte hypertrophy	25
Ionic dependency, sensitivity to transport inhibitors and signal transduction of propionate-induced anion secretion in rat caecum	25
Sophoricoside ameliorates cerebral ischemia-reperfusion injury dependent on activating AMPK	25
Valdecoxib blocks rat TRPV2 channels	25
Ginkgolide A alleviates cardiac remodeling in mice with myocardial infarction via binding to matrix metalloproteinase-9 to attenuate inflammation	25
Amelioration of D-galactose-induced hyposalivation in aging rats by the GLP-1 receptor agonist Exendin-4	25
SAP30BP aggravates mitochondrial-related ferroptosis in diabetic cardiomyopathy by regulating MFN2-ACSL4 axis	24
GW501516 facilitated tumor immune escape by inhibiting phagocytosis	24
Nonadditive transcriptional change analysis identifies regulators for ginsenoside Rg3 to alleviate synergistic cytokine production in TLR2/3 dual-stimulated macrophages	24
Corrigendum to “Combination therapy with citalopram, bupropion, and lithium for the amelioration of the depressive-related effects induced by dexamethasone in male mice” [Eur. J. Pharmacol. 1002 (2025	24
Editorial Board	24
The next frontier in multiple sclerosis therapies: Current advances and evolving targets	24
Kurarinone induced p53-independent G0/G1 cell cycle arrest by degradation of K-RAS via WDR76 in human colorectal cancer cells	24
Sodium houttuyfonate protects against cardiac injury by regulating cardiac energy metabolism in diabetic rats	24
Imperatorin attenuates CCl4-induced cirrhosis and portal hypertension by improving vascular remodeling and profibrogenic pathways	24
In vivo and In vitro Crosstalk Among CBD, Aβ, and endocannabinoid system enzymes and receptors	24
Effects of 101BHG-D01, a novel M receptor antagonism, on allergic rhinitis in animal models and its mechanism	24
Desmopressin enhances random-pattern skin flap survival in rats: Possible role of vasopressin Type-1a and 2 receptors	24
Recent trends in diabetic wound healing with nanofibrous scaffolds	24
PAI-1 siRNA-loaded biomimetic nanoparticles for ameliorating diminished ovarian reserve and inhibiting ovarian fibrosis	24
Inhibiting 5-HT2C receptor in the hippocampus rescues EphB2-dependent memory impairment in mice	24
Investigation of the effects of losartan and captopril on rotenone-induced inflammation via TLR4/NLRP3 pathway: An integrative in vitro and in silico study	24
Editorial Board	24
Retraction notice to “Apoptotic cell death: A possible key event in mediating the in vitro anti-proliferative effect of a novel copper(II) complex, [Cu(4-Mecdoa) (phen)2] (phen = phenanthroline, 4-Mec	24
Tulipalin A suppressed the pro-inflammatory polarization of M1 macrophage and mitigated the acute lung injury in mice via interference DNA binding activity of NF-κB	23
Comprehensive analysis of transcriptomics and metabolomics to illustrate the underlying mechanism of helenalin against hepatic fibrosis	23
Epac as a tractable therapeutic target	23
Editorial Board	23
Novel prospects in targeting neurodegenerative disorders via autophagy	23
Hinokitiol protects gastric injury from ethanol exposure via its iron sequestration capacity	23
Therapeutic effects of finerenone and exenatide on diabetes-induced heart failure: A combined approach targeting inflammation and oxidative stress	23
Effects of decrease in Klotho protein expression on insulin signaling and levels of proteins related to brain energy metabolism	23
Mutational effects of the asparagine198 and glutamate223 residues on the human norepinephrine transporter on basal and HIV-1 Tat protein-induced inhibition of dopamine transport	23
Effect of hyperoside on osteoporosis in ovariectomized mice through estrogen receptor α/ITGβ3 signaling pathway	23
Beyond chemotherapy: Exploring 5-FU resistance and stemness in colorectal cancer	23
Cuproptosis induced by curcumin interfering with proliferation and energy metabolism in colorectal cancer: 3D tumor model and computational simulations reveal curcumin inhibition of HSPD1 and CALCOCO2	22
Simultaneous nanocarrier-mediated delivery of siRNAs and chemotherapeutic agents in cancer therapy and diagnosis: Recent advances	22
Harringtonine metabolites: 5'-de-O-methylharringtonine and cephalotaxine, targeting spike protein and TMPRSS2 to double block membrane fusion of SARS-CoV-2 and its variants	22
A novel nordihydroguaiaretic acid analog, compound 3a, alleviates acute lung injury by exerting antiapoptotic and antiinflammatory effects	22
Biopharmaceuticals against substance use disorders – Present and future	22
Synthetic flavokawain analog (E)-1-(2′-hydroxy-4′,6′-dimethoxyphenyl)-3-(3-methoxy-4-(3-morpholinopropoxy)phenyl)prop-2-en-1-one (FK-morph) effectively regresses endometriotic implants in rats	22
Combination therapy with cetirizine and anti-PD-1 antibody suppresses colitis-induced colon tumor formation in mice	22
Modulation of SIRT6 related signaling pathways of p-AKT/mTOR and NRF2/HO-1 by memantine contributes to curbing the progression of tamoxifen/HFD-induced MASH in rats	22
Dehydrozingerone alleviates pulmonary fibrosis via inhibition of inflammation and epithelial-mesenchymal transition by regulating the Wnt/β-catenin pathway	22
Pharmacogenetics of angiotensin-converting enzyme inhibitors (ACEI) and angiotensin II receptor blockers (ARB) in cardiovascular diseases	22
BRD4 as a therapeutic target for atrial fibrosis and atrial fibrillation	22
MCPIP1 regulates focal adhesion kinase and Rho GTPase-dependent migration in clear cell renal cell carcinoma	22
Synthesis of 2-(2-(4-thioxo-3H-1,2-dithiole-5-yl) phenoxy)ethyl)isoindole-1,3-thione, a novel hydrogen sulfide-releasing phthalimide hybrid, and evaluation of its activity in models of inflammatory pa	22
Discovery of cinnamoyl–flavonoid hybrid derivatives as inhibitors of SARS-CoV-2 Mpro and anti-inflammatory agents: Experimental and in silico insights into their efficacy against lipopolysaccharide-in	22
Targeting TRPs in autophagy regulation and human diseases	22
Emerging therapeutic avenues in cardiac amyloidosis	22
A combination of peripherally restricted CB1 and CB2 cannabinoid receptor agonists reduces bladder afferent sensitisation in cystitis	22
Carbon monoxide attenuates cellular senescence-mediated pulmonary fibrosis via modulating p53/PAI-1 pathway	22
Comparison of the effects of peficitinib and tofacitinib in the adjuvant-induced arthritis rat model	22
Anticancer activity and metabolic alteration in colon and prostate cancer cells by novel moxifloxacin conjugates with fatty acids	22
Overexpressed mitogen-and stress-activated protein kinase 1 promotes the resistance of cytarabine in acute myeloid leukemia through brahma related gene 1-mediated upregulation of heme oxygenase-1	22
lncRNA BBOX1-AS1 silencing inhibits esophageal squamous cell cancer progression by promoting ferroptosis via miR-513a-3p/SLC7A11 axis	21
Effects of proprotein convertase subtilisin-kexin type 9 inhibitors on inflammatory and hemostatic parameters in post myocardial infarction patients	21
Functional studies and molecular dynamics reveal BPP-BrachyNH2-induced relaxation in male rat small mesenteric arteries via binding to argininosuccinate synthase	21
Michael acceptor-dependent pro-oxidative intervention against angiogenesis by [6]-dehydroshogaol, a pungent constituent of ginger	21
Escaping a second time round: A replication and extension study on the motivational climate of and knowledge gain in a general pharmacology course	21
Diosgenin inhibits prostate cancer progression by inducing UHRF1 protein degradation	21
Esketamine improves cognitive function in sepsis-associated encephalopathy by inhibiting microglia-mediated neuroinflammation	21
Establishment of a murine chronic proximal thoracic aortic aneurysm model by combining periaortic elastase application with oral BAPN administration	21
Mechanisms underlying the efficacy and limitation of dopa and tetrahydrobiopterin therapies for the deficiency of GTP cyclohydrolase 1 revealed in a novel mouse model	21
Catalyzing biopharma leaders: Sparking innovative medicines through inclusive engagement	21
Silibinin eliminates mitochondrial ROS and restores autophagy through IL6ST/JAK2/STAT3 signaling pathway to protect cardiomyocytes from doxorubicin-induced injury	21
Cordycepin deteriorates 5’ fluorouracil-induced anaemia by AMPK activation	21
New insights on the differential interaction of sulfiredoxin with members of the peroxiredoxin family revealed by protein-protein docking and experimental studies	21
Exploring the landscape of pharmacology education in Health Professions Programs: From historical perspectives to current approaches to teaching	21
MitoTEMPO protects against podocyte injury by inhibiting NLRP3 inflammasome via PINK1/Parkin pathway-mediated mitophagy	21
The endocrine disruptor vinclozolin causes endothelial injury via eNOS/Nox4/IRE1α signaling	20
Protective effects of atorvastatin on testicular dysfunction and reduced sperm quality induced by high-fat diet in mice: The inhibitory mechanism of oxidative stress	20