European Journal of Pharmacology

Article	Citations
1, 8-cineole protects against ISO-induced heart failure by inhibiting oxidative stress and ER stress in vitro and in vivo	219
High urea induces anxiety disorders associated with chronic kidney disease by promoting abnormal proliferation of OPC in amygdala	190
Sacubitril/valsartan reduces susceptibility to atrial fibrillation by improving atrial remodeling in spontaneously hypertensive rats	136
Discovery of a highly potent kinase inhibitor capable of overcoming multiple imatinib-resistant ABL mutants for chronic myeloid leukemia (CML)	136
Peptides originally derived from Chilobrachys jingzhao tarantula venom possess beneficial effects on pancreatic beta cell health and function	96
The pathogenesis of depression: Roles of connexin 43-based gap junctions and inflammation	94
Luteolin alleviates diabetic cardiac injury related to inhibiting SHP2/STAT3 pathway	89
Students’ perspective on the Dutch National Pharmacotherapy Assessment, a national survey study among final-year medical students	89
Role of 11β-hydroxysteroid dehydrogenase type 1 inhibition in the antiobesity effect of J2H-1702 on adipocytes and a high-fat diet-induced NASH model	84
Retraction notice to “Tanshinone IIA protects hypoxia-induced injury by preventing microRNA-28 up-regulation in PC-12 cells” [Eur. J. Pharmacol. 854 (2019) 265–271]	83
ACSL family: The regulatory mechanisms and therapeutic implications in cancer	80
Losartan and metabolite EXP3179 activate endothelial function without lowering blood pressure in AT2 receptor KO mice	80
Targeting beta-catenin signaling for prevention of colorectal cancer – Nutraceutical, drug, and dietary options	77
Downregulation of PDCD4 through STAT3/ATF6/autophagy mediates MIF-induced PASMCs proliferation/migration and vascular remodeling	75
Kinsenoside mitigates myocardial ischemia/reperfusion-induced ferroptosis via activation of the Akt/Nrf2/HO-1 pathway	71
Icariside II mitigates myocardial infarction by balancing mitochondrial dynamics and reducing oxidative stress through the activation of Nrf2/SIRT3 signaling pathway	70
CT2-3 induces cell cycle arrest and apoptosis in rheumatoid arthritis fibroblast-like synoviocytes through regulating PI3K/AKT pathway	68
Theaflavine inhibits hepatic stellate cell activation by modulating the PKA/LKB1/AMPK/GSK3β cascade and subsequently enhancing Nrf2 signaling	67
Effects of oleanolic acid and ursolic acid on depression-like behaviors induced by maternal separation in mice	67
Proteomic analysis reveals that ACSL4 activation during reflux esophagitis contributes to ferroptosis-mediated esophageal mucosal damage	65
Effects of sacubitril-valsartan on aging-related cardiac dysfunction	65
Abaloparatide: A review of preclinical and clinical studies	63
The mechanism of the imbalance between proliferation and ferroptosis in pulmonary artery smooth muscle cells based on the activation of SLC7A11	58
Inhibiting PRMT1 protects against CoNV by regulating macrophages through the FGF2/PI3K/Akt pathway	56
Cerebroprotein hydrolysate-I ameliorates cognitive dysfunction in APP/PS1 mice by inhibiting ferroptosis via the p53/SAT1/ALOX15 signalling pathway	55

Arctigenin, an anti-tumor agent; a cutting-edge topic and up-to-the-minute approach in cancer treatment	55
The mechanism by which ATP regulates alcoholic steatohepatitis through P2X4 and CD39	54
Application and advantages of zebrafish model in the study of neurovascular unit	54
Hypoxia-induced TRPM7 promotes glycolytic metabolism and progression in hepatocellular carcinoma	53
Spinal dopaminergic D1-and D2-like receptors have a sex-dependent effect in an experimental model of fibromyalgia	52
Propionate ameliorates diabetes-induced neurological dysfunction through regulating the PI3K/Akt/eNOS signaling pathway	50
Melanocortin receptor-4 mediates the anorectic effect induced by the nucleus tractus solitarius injection of glucagon-like Peptide-2 in fasted rats	50
Carbon monoxide-releasing molecule-2 ameliorates postresuscitation myocardial dysfunction in rat via mitochondrial-mediated apoptosis pathway and the regulation of mitochondrial dynamics	49
Licochalcone A induces G2/M phase arrest and apoptosis via regulating p53 pathways in esophageal cancer: In-vitro and in-vivo study	49
Catalpol ameliorates LPS-induced inflammatory response by activating AMPK/mTOR signaling pathway in rat intestinal epithelial cells	48
Sis-25, a meroditerpenoid derivative with a cyclobutane scaffold, inhibits activated T cell proliferation by targeting GSK3β in vitro and in vivo	48
Non-coding RNAs and exosomal ncRNAs in multiple myeloma: An emphasis on molecular pathways	47
Propranolol modulation of tetrodotoxin-resistant Na+ channels in dural afferent neurons	47
Dexmedetomidine inhibits LPS-induced inflammatory responses through peroxisome proliferator-activated receptor gamma (PPARγ) activation following binding to α2 adrenoceptors	47
Icariin arrests cell cycle progression and induces cell apoptosis through the mitochondrial pathway in human fibroblast-like synoviocytes	46
Crosstalk relationship between adiponectin receptors, PPAR-γ and α-adrenoceptors in renal vasculature of diabetic WKYs	44
Tenacissoside H repressed the progression of glioblastoma by inhibiting the PI3K/Akt/mTOR signaling pathway	43
Curcumin nicotinate increases LDL cholesterol uptake in hepatocytes through IDOL/LDL-R pathway regulation	43
Inhibition of the Notch signaling pathway attenuates progression of cell motility, metastasis, and epithelial-to-mesenchymal transition-like phenomena induced by low concentrations of cisplatin in ost	42
Fatty acid-binding protein 4 in kidney diseases: From mechanisms to clinics	41
Editorial Board	41
Amorphous selenium nanodots alleviate non-alcoholic fatty liver disease via activating VEGF receptor 1 to further inhibit phosphorylation of JNK/p38 MAPK pathways	41
Editorial Board	40
Endogenous opioid and cannabinoid systems modulate the muscle pain: A pharmacological study into the peripheral site	40
Methylglyoxal impairs ATP- and UTP-induced relaxation in the rat carotid arteries	40
Naringenin reduces oxidative stress and necroptosis, apoptosis, and pyroptosis in random-pattern skin flaps by enhancing autophagy	40
Editorial Board	39
The other side of the coin: Positive view on the role of opioids in cancer	38
Editorial Board	38
Spinal endomorphins attenuate burn-injury pain in male mice by inhibiting p38 MAPK signaling pathway through the mu-opioid receptor	38
Pharmacological characterization of AS2690168, a novel small molecule RANKL signal transduction inhibitor	38
Sodium butyrate alleviates right ventricular hypertrophy in pulmonary arterial hypertension by inhibiting H19 and affecting the activation of let-7g-5p/IGF1 receptor/ERK	37
Isorhynchophylline ameliorates the progression of osteoarthritis by inhibiting the NF-κB pathway	37
Protective effect of 5,6,7,8-Tetrahydroxyflavone on high altitude cerebral edema in rats	37
SCP-7, a germacrane-type sesquiterpene lactone derivative, induces ROS-mediated apoptosis in NSCLC cells in vitro and in vivo	37
Ginsenoside Rg1 promotes fetal hemoglobin production in vitro: A potential therapeutic avenue for β-thalassemia	35
Quinazoline alpha-adrenoreceptor blockers as an adjunct cancer treatment: From bench to bedside	35
Pterostilbene and 6-shogaol exhibit inhibitory effects on sunitinib resistance and motility by suppressing the RLIP76-initiated Ras/ERK and Akt/mTOR pathways in renal cancer cells	35
Editorial Board	34
Editorial Board	34
The synergistic effects of opioid and neuropeptide B/W in rat acute inflammatory and neuropathic pain models	34
Time-dependent influence of infliximab on hemodynamic responses and cardiac injuries of isoproterenol-induced myocardial infarction in rats	34
Antagonizing interleukin-5 receptor ameliorates dextran sulfate sodium-induced experimental colitis in mice through reducing NLRP3 inflammasome activation	34
Platycodin D suppresses proliferation, migration, and invasion of human glioblastoma cells through regulation of Skp2	33
Pancreastatin inhibitor PSTi8 ameliorates streptozotocin-induced diabetes by suppressing hepatic glucose production	33
Editorial Board	33
Editorial Board	33
Editorial Board	33
Editorial Board	33
17β-estradiol and ureteral contractility: A role for the G protein-coupled estrogen receptor	33

Editorial Board	32
Editorial Board	32
Reno-protective potential of sodium glucose cotransporter-2 (SGLT2) inhibitors: Summary evidence from clinical and real-world data	32
Role of nitric oxide, bradykinin B2 receptor, and TRPV1 in the airway alterations caused by simvastatin in rats	32
USP22 aggravated diabetic renal tubulointerstitial fibrosis progression through deubiquitinating and stabilizing Snail1	32
Editorial Board	32
Editorial Board	32
Mechanosensitive modulation of peristaltic contractions in the mouse renal pelvis	31
sGC agonist BAY1021189 promotes thoracic aortic dissection formation by accelerating vascular smooth muscle cell phenotype switch	31
Peptide identification of hepatocyte growth-promoting factor and its function in cytoprotection and promotion of liver cell proliferation through the JAK2/STAT3/c-MYC pathway	31
Lack of evidence for positive reinforcing and prosocial effects of MDMA in pair-housed male and female rats	31
Single-cell transcriptome analysis reveals dynamic changes of the preclinical A549 cancer models, and the mechanism of dacomitinib	30
Discovery of a highly potent pan-RAF inhibitor IHMT-RAF-128 for cancer treatment	30
Editorial Board	30
The role of NFAT in the pathogenesis and targeted therapy of hematological malignancies	30
Editorial Board	30
Editorial Board	30
The bradycardic agent ivabradine decreases conduction velocity in the AV node and in the ventricles in-vivo	30
Orexin receptors regulate hippocampal sharp wave-ripple complexes in ex vivo slices	30
Editorial Board	29
Possible involvement of brain hydrogen sulphide in the inhibition of the rat micturition reflex induced by activation of brain alpha7 nicotinic acetylcholine receptors	29
Research progress on the potential novel analgesic BU08028	29
Calcium handling genes are regulated by promoter DNA methylation in colorectal cancer cells	29
17β-Estradiol promotes angiogenesis of stria vascular in cochlea of C57BL/6J mice	29
Eukaryotic elongation factor 2 kinase inhibitor, A484954 inhibits perivascular sympathetic nerve stimulation-induced vasoconstriction in isolated renal artery	28
Ursodesoxycholic acid is an FFA4 agonist and reduces hepatic steatosis via FFA4 signaling	28
Hydrogen sulfide ameliorates hypertension and vascular dysfunction induced by insulin resistance in rats by reducing oxidative stress and activating eNOS	28
GPR146 regulates pulmonary vascular remodeling by promoting pulmonary artery smooth muscle cell proliferation through 5-lipoxygenase	28
Editorial Board	28
Targeted treprostinil delivery inhibits pulmonary arterial remodeling	28
A polypeptide derived from pilose antler ameliorates CUMS-induced depression-like behavior by SENP2-PLCβ4 signaling axis	28
Arctigenin inhibits abnormal germinal center reactions and attenuates murine lupus by inhibiting IFN-I pathway	28
Cyclosporin A up-regulated thromboxane A2 receptor through activation of MAPK and NF-κB pathways in rat mesenteric artery	28
Sodium butyrate ameliorates sepsis-associated lung injury by enhancing gut and lung barrier function in combination with modulation of CD4+Foxp3+ regulatory T cells	28
Editorial Board	28
Downregulation of B4GALT5 attenuates cardiac fibrosis through Lumican and Akt/GSK-3β/β-catenin pathway	28
Editorial Board	27
Protocatechuic acid attenuates chronic unpredictable mild stress induced-behavioral and biochemical alterations in mice	27
Effect of mitochondrial complex III inhibitors on the regulation of vascular tone in porcine coronary artery	27
Fucoxanthin mitigates valproic acid-induced autistic behavior through modulation of the AKT/GSK-3β signaling pathway	27
Interaction of the preferential D3 agonist (+)PHNO with dopamine D3-D2 receptor heterodimers and diverse classes of monoamine receptor: relevance for PET imaging	27
Integrating network pharmacology, transcriptomics, and molecular simulation to reveal the mechanism of tert-butylhydroquinone for treating diabetic retinopathy	27
Is the forming of neuronal network activity in human-induced pluripotent stem cells important for the detection of drug-induced seizure risks?	27
Early growth response 1/Krüppel-like factor 5 pathway inhibitor alleviates lipopolysaccharide-induced lung injury by promoting autophagy	26
Editorial Board	26
Phosphodiesterase-1 inhibitor modulates Ca2+ regulation in sirtuin 1-deficient mouse cardiomyocytes	26
Phenotypic screening identifies hydroxypyridone anti-fungals as novel medicines for the prevention of hypertrophic scars	26
A focus on Rho/ROCK signaling pathway: An emerging therapeutic target in depression	26
RTA-dh404 decreased oxidative stress in mice ischemic limbs and augmented efficacy of therapeutic angiogenesis by intramuscular injection of adipose-derived regenerative cells in the limbs	26
Nicorandil protects against coronary microembolization-induced myocardial injury by suppressing cardiomyocyte pyroptosis via the AMPK/TXNIP/NLRP3 signaling pathway	26
Nitric oxide modulates tapentadol antinociceptive tolerance and physical dependence	26
Involvement of interstitial cells of Cajal in nicotinic acetylcholine receptor-induced relaxation of the porcine lower esophageal sphincter	26
CFNC, a neocryptolepine derivative, inhibited the growth of gastric cancer AGS cells by inhibiting PI3K/AKT signaling pathway	25
Inhibiting the growth of ovarian cancer cells in vitro and in vivo by a small molecular inhibitor targeting La-RNA interactions	25
Non-genomic uterorelaxant actions of corticosteroid hormones in rats: An in vitro and in vivo study	25
Estrogen protects against acidosis-mediated articular chondrocyte injury by promoting ASIC1a protein degradation	25
The emerging roles of HDACs and their therapeutic implications in cancer	25
Exosomes as biomarkers and therapeutic measures for ischemic stroke	25
In vitro assessment of the binding and functional responses of ozanimod and its plasma metabolites across human sphingosine 1-phosphate receptors	25
Dual effects of atorvastatin on angiogenesis pathways in the differentiation of mesenchymal stem cells	25
Therapeutic effects of masitinib on abnormal mechanoreception in a mouse model of tourniquet-induced extremity ischemia-reperfusion	25
Anemoside B4 ameliorates dextran sulfate sodium (DSS)-induced colitis through inhibiting NLRP3 inflammasome and modulating gut microbiota	25
Breast milk MSCs upregulated β-cells PDX1, Ngn3, and PCNA expression via remodeling ER stress /inflammatory /apoptotic signaling pathways in type 1 diabetic rats	25
Editorial Board	25
Research progress of phosphatidylinositol 4-kinase and its inhibitors in inflammatory diseases	25
Nicotine suppresses central post-stroke pain via facilitation of descending noradrenergic neuron through activation of orexinergic neuron	25
Apocynin attenuates diabetic cardiomyopathy by suppressing ASK1-p38/JNK signaling	25
Vorinostat targets UBE2C to reverse epithelial-mesenchymal transition and control cervical cancer growth through the ubiquitination pathway	25
Characterisation of bis(4-aminoquinoline)s as α1A adrenoceptor allosteric modulators	25
PI3K/mTOR dual-inhibition with VS-5584 enhances anti-leukemic efficacy of ponatinib in blasts and Ph-negative LSCs of chronic myeloid leukemia	24
IP3R1 dysregulation via mir-200c-3p/SSFA2 axis contributes to taxol resistance in head and neck cancer	24
Treprostinil palmitil inhibits the hemodynamic and histopathological changes in the pulmonary vasculature and heart in an animal model of pulmonary arterial hypertension	24
Immunomodulatory effect of protocatechuic acid on cyclophosphamide induced brain injury in rat: Modulation of inflammosomes NLRP3 and SIRT1	24
Glycyrrhetinic acid attenuates endoplasmic reticulum stress-induced hepatocyte apoptosis via CHOP/DR5/Caspase 8 pathway in cholestasis	24
Flavokawain A ameliorates pulmonary fibrosis by inhibiting the TGF-β signaling pathway and CXCL12/CXCR4 axis	24
Inhibitors of angiotensin I converting enzyme potentiate fibromyalgia-like pain symptoms via kinin receptors in mice	24
Hydrogen sulphide protects mice against the mutual aggravation of cerebral ischaemia/reperfusion injury and colitis	24
Effects of Isoprenaline on ventricular myocyte shortening and Ca2+ transport in the Zucker rat	24
Syringaresinol attenuates sepsis-induced cardiac dysfunction by inhibiting inflammation and pyroptosis in mice	23
Caveolin-1 attenuates acetaminophen aggravated lipid accumulation in alcoholic fatty liver by activating mitophagy via the Pink-1/Parkin pathway	23

Assessment of proarrhythmogenic risk for chloroquine and hydroxychloroquine using the CiPA concept	23
A novel dual mode-of-action anti-hyperalgesic compound in rats which is neuroprotective and promotes neuroregeneration	23
Resveratrol modulates Toxoplasma gondii infection induced liver injury by intervening in the HMGB1/TLR4/NF-κB signaling pathway	23
Effect of doxorubicin on cardiac lipid metabolism-related transcriptome and the protective activity of Alda-1	23
Regulation of human endothelial cell migration by oral contraceptive estrogen receptor ligands	23
Nitisinone attenuates cartilage degeneration and subchondral osteoclastogenesis in osteoarthritis and concomitantly inhibits the cGAS/STING/NF-κB pathway	23
Kaempferol protects against cardiovascular abnormalities induced by nitric oxide deficiency in rats by suppressing the TNF-α pathway	23
Cyclophilin D-mediated angiotensin II-induced NADPH oxidase 4 activation in endothelial mitochondrial dysfunction that can be rescued by gallic acid	23
Itaconate prolongs the healthy lifespan by activating UPRmt in Caenorhabditis elegans	23
In vitro pharmacological characterization of growth hormone secretagogue receptor ligands using the dynamic mass redistribution and calcium mobilization assays	22
Harnessing the neuroprotective effect of oral administration of benfotiamine in MPTP induced Parkinson's disease in rats	22
The role of cardiomyocyte senescence in cardiovascular diseases: A molecular biology update	22
A review of potential suggested drugs for coronavirus disease (COVID-19) treatment	22
Novel combinatorial autophagy inhibition therapy for triple negative breast cancers	22
Impact of HDAC6-mediated progesterone receptor expression on the response of breast cancer cells to hormonal therapy	22
Autophagic inhibitor ROC-325 ameliorates glomerulosclerosis and podocyte injury via inhibiting autophagic flux in experimental FSGS mice	22
HucMSC exosomes attenuate partial bladder outlet obstruction-induced renal injury and cell proliferation via the Wnt/β-catenin pathway	22
Astaxanthin inhibits apoptosis in a cell model of tauopathy by attenuating endoplasmic reticulum stress and unfolded protein response	22
Dapagliflozin alleviates right heart failure by promoting collagen degradation by reducing ROS levels	22
The central melanocortin system as a treatment target for obesity and diabetes: A brief overview	22
Aging in chronic lung disease: Will anti-aging therapy be the key to the cure?	22
Bazedoxifene attenuates dextran sodium sulfate-induced colitis in mice through gut microbiota modulation and inhibition of STAT3 and NF-κB pathways	22
ADAM28 from both endothelium and gastric cancer cleaves von Willebrand Factor to eliminate von Willebrand Factor-induced apoptosis of gastric cancer cells	22
Cardiovascular effects of Roflumilast during sepsis: Risks or benefits?	22
Efficacy of probiotics on improvement of health outcomes in cirrhotic liver disease patients: A systematic review and meta-analysis of randomised controlled trials	22
Palmatine alleviates cardiac fibrosis by inhibiting fibroblast activation through the STAT3 pathway	22
Deciphering the role of siRNA in anxiety and depression	22
Self-propelled micro/nanobots: A new insight into precisely targeting cancerous cells through intelligent and deep cancer penetration	22
The antidiabetic drug ipragliflozin induces vasorelaxation of rabbit femoral artery by activating a Kv channel, the SERCA pump, and the PKA signaling pathway	22
Investigating the impact of protein S-sulfhydration modification on vascular diseases: A comprehensive review	22
Anxiety disorders: Treatments, models, and circuitry mechanisms	22
β-caryophyllene blocks reactive oxygen species-mediated hyperlipidemia in isoproterenol-induced myocardial infarcted rats	22
Edaravone dexborneol ameliorates cognitive impairment by regulating the NF-κB pathway through AHR and promoting microglial polarization towards the M2 phenotype in mice with bilateral carotid artery s	21
Phosphoinositide 3-kinase (PI3K) classes: From cell signaling to endocytic recycling and autophagy	21
AMPK activation by metformin protects against pulmonary hypertension in rats and relaxes isolated human pulmonary artery	21
An 8-aminoquinoline-naphthyl copper complex causes apoptotic cell death by modulating the expression of apoptotic regulatory proteins in breast cancer cells	21
Dapagliflozin attenuates fat accumulation and insulin resistance in obese mice with polycystic ovary syndrome	21
Inhibition of TRPC3 channels suppresses seizure susceptibility in the genetically-epilepsy prone rats	21
Editorial Board	21
Artepillin C, a major component of Brazilian green propolis, inhibits endoplasmic reticulum stress and protein aggregation	21
Oridonin, a small molecule inhibitor of cancer stem cell with potent cytotoxicity and differentiation potential	21
Corosolic acid attenuates platelet-derived growth factor signaling in macrophages and smooth muscle cells of pulmonary arterial hypertension	21
Targeting KPNB1 with genkwadaphnin suppresses gastric cancer progression through the Nur77-mediated signaling pathway	21
Do neprilysin inhibitors walk the line? Heart ameliorative but brain threatening!	21
Hydrogen sulfide as a neuromodulator of the vascular tone	21
Fudosteine attenuates acute lung injury in septic mice by inhibiting pyroptosis via the TXNIP/NLRP3/GSDMD pathway	21
Enhanced targeting of 3D pancreatic cancer spheroids by aptamer-conjugated polymeric micelles with deep tumor penetration	21
Antioxidant effect of ascorbic acid against cisplatin-induced nephrotoxicity and P-glycoprotein expression in rats	21
Anti-tumor activity of 5-aminoimidazole-4-carboxamide riboside with AMPK-independent cell death in human adult T-cell leukemia/lymphoma	21
Dendritic cells in Parkinson's disease: Regulatory role and therapeutic potential	21
HnRNPK and lysine specific histone demethylase-1 regulates IP-10 mRNA stability in monocytes	20
Validation and characterization of oxycodone physical dependence in C57BL/6J mice	20
Anthelmintic niclosamide attenuates pressure-overload induced heart failure in mice	20
The PP2A inhibitor LB-100 mitigates lupus nephritis by suppressing tertiary lymphoid structure formation	20
Morphine timing-dependent modulation of TRPV1 phosphorylation correlates with differential morphine effects on myocardial ischemia/reperfusion injury	20
Hippocampal Galectin-3 knockdown alleviates lipopolysaccharide-induced neurotoxicity and cognitive deficits by inhibiting TLR4/NF-кB signaling in aged mice	20
Inhibition of Alzheimer's disease by 4-octyl itaconate revealed by RNA-seq transcriptome analysis	20
Glutamic oxaloacetic transaminase 1 as a potential target in human cancer	20
Multi-omics study on the molecular mechanism of anlotinib in regulating tumor metabolism	20
Tartaric acid ameliorates experimental non-alcoholic fatty liver disease by activating the AMP-activated protein kinase signaling pathway	20
Anti-inflammatory effects of theaflavin-3′-gallate during influenza virus infection through regulating the TLR4/MAPK/p38 pathway	20
Laccase-mediated functionalization of natamycin by gallic acids for the therapeutic effect on Aspergillus fumigatus keratitis	20
Epigenetic modifications in Parkinson's disease: A critical review	20
Kaempferol impairs aerobic glycolysis against melanoma metastasis via inhibiting the mitochondrial binding of HK2 and VDAC1	19
Glucocorticoid receptor modulator CORT125385 alleviates diet-induced hepatosteatosis in male and female mice	19
Anti-cancer effect of combined action of anti-MUC1 and rosmarinic acid in AGS gastric cancer cells	19
Integrative experimental validation of concomitant miRNAs and transcription factors with differentially expressed genes in acute myocardial infarction.	19
Protein detection and localization of the non-selective cation channel TRPC6 in the human heart	19
MiR-29a inhibits MPP + - Induced cell death and inflammation in Parkinson's disease model in vitro by potential targeting of MAVS	19
Cynandione A causes a dynamic change in SIRT1 nuclear trafficking via PKA signaling and beige adipocyte differentiation in 3T3-L1 cells	19
Resveratrol alleviates acute lung injury through regulating PLSCR-3-mediated mitochondrial dysfunction and mitophagy in a cecal ligation and puncture model	19
Salicylic acid in ginseng root alleviates skin hyperpigmentation disorders by inhibiting melanogenesis and melanosome transport	19
Metformin turns 62 in pharmacotherapy: Emergence of non-glycaemic effects and potential novel therapeutic applications	19
Gamma-decanolactone: Preliminary evaluation as potential antiparkinsonian drug	19
Promising drug candidates for the treatment of polycystic ovary syndrome (PCOS) as alternatives to the classical medication metformin	19
Therapeutic potential of lipid-lowering probiotics on the atherosclerosis development	19
Current progress on the mechanisms of hyperhomocysteinemia-induced vascular injury and use of natural polyphenol compounds	19
Calycosin-7-O-β-D-glucoside attenuates palmitate-induced lipid accumulation in hepatocytes through AMPK activation	19
Resveratrol suppresses the reprogramming of macrophages into an endotoxin-tolerant state through the activation of AMP-activated protein kinase	19
Crosstalk between the liver and kidney in diabetic nephropathy	19
Endogenous asymmetric dimethylarginine accumulation precipitates the cardiac and mitochondrial dysfunctions in type 1 diabetic rats	19
Purpurin ameliorated neuropathic allodynia and hyperalgesia by modulating neuronal mitochondrial bioenergetics and redox status in type 1 diabetic mice	18
Escin ameliorates CUMS-induced depressive-like behavior via BDNF/TrkB/CREB and TLR4/MyD88/NF-κB signaling pathways in rats	18
Tyrosol attenuates NASH features by reprogramming the hepatic immune milieu	18
Improved antiallodynic, antihyperalgesic and anti-inflammatory response achieved through potential prodrug of curcumin, curcumin diethyl diglutarate in a mouse model of neuropathic pain	18
Hypoxia promotes the expression of Von Willebrand factor in breast cancer cells by up-regulating the transcription factor YY1 and down-regulating the hsa-miR-424	18
Gut microbiota and Alzheimer's disease: Exploring natural product intervention and the Gut–Brain axis for therapeutic strategies	18
Peficitinib halts acute kidney injury via JAK/STAT3 and growth factors immunomodulation	18
Suppression of hypoxia-induced CAV1 autophagic degradation enhances nanoalbumin-paclitaxel transcytosis and improves therapeutic activity in pancreatic cancer	18
Liraglutide chronic treatment prevents development of tolerance to antiseizure effects of diazepam in genetically epilepsy prone rats	18
IL-1 receptor-associated kinase family proteins: An overview of their role in liver disease	18
Myricanol represses renal fibrosis by activating TFAM and ZNRF1 to inhibit tubular epithelial cells ferroptosis	18
Glibenclamide reverses cardiac damage and NLRP3 inflammasome activation associated with a high refined sugar diet	18
P2X3 and P2X2/3 receptors inhibition produces a consistent analgesic efficacy: A systematic review and meta-analysis of preclinical studies	18
AM251, a cannabinoid receptor 1 antagonist, prevents human fibroblasts differentiation and collagen deposition induced by TGF-β – An in vitro study	18