European Journal of Pharmacology

Article	Citations
Macrophage M1/M2 polarization	874
Alzheimer's disease: Recent treatment strategies	290
Treatment for COVID-19: An overview	213
COVID-19 vaccine: A recent update in pipeline vaccines, their design and development strategies	182
siRNA: Mechanism of action, challenges, and therapeutic approaches	143
Ferroptosis involves in renal tubular cell death in diabetic nephropathy	112
ACSL family: The regulatory mechanisms and therapeutic implications in cancer	105
Dexamethasone: Therapeutic potential, risks, and future projection during COVID-19 pandemic	104
Naringenin and naringin in cardiovascular disease prevention: A preclinical review	102
Geniposide alleviates diabetic nephropathy of mice through AMPK/SIRT1/NF-κB pathway	92
Flavonols as potential antiviral drugs targeting SARS-CoV-2 proteases (3CLpro and PLpro), spike protein, RNA-dependent RNA polymerase (RdRp) and angiotensin-converting enzyme II receptor (ACE2)	91
In silico pharmacokinetic and molecular docking studies of natural flavonoids and synthetic indole chalcones against essential proteins of SARS-CoV-2	90
Application of methylene blue -vitamin C –N-acetyl cysteine for treatment of critically ill COVID-19 patients, report of a phase-I clinical trial	89
Current advancements and future perspectives of immunotherapy in colorectal cancer research	88
Virology, pathogenesis, diagnosis and in-line treatment of COVID-19	85
COVID-19: A review of the proposed pharmacological treatments	84
A review of potential suggested drugs for coronavirus disease (COVID-19) treatment	83
Remdesivir for treatment of COVID-19; an updated systematic review and meta-analysis	77
Possibility of magnesium supplementation for supportive treatment in patients with COVID-19	76
Curcumin, a traditional spice component, can hold the promise against COVID-19?	75
Neuroprotective role of polyphenols against oxidative stress-mediated neurodegeneration	74
Role of natural products for the treatment of Alzheimer's disease	73
Positive allosteric modulation of GABAA receptors by a novel antiepileptic drug cenobamate	68
In silico molecular docking analysis for repurposing therapeutics against multiple proteins from SARS-CoV-2	67
Targeting STAT3 in cancer and autoimmune diseases	67

Astragalus polysaccharide prevents ferroptosis in a murine model of experimental colitis and human Caco-2 cells via inhibiting NRF2/HO-1 pathway	66
Empagliflozin ameliorates endothelial dysfunction and suppresses atherogenesis in diabetic apolipoprotein E-deficient mice	64
Beta-sitosterol attenuates insulin resistance in adipose tissue via IRS-1/Akt mediated insulin signaling in high fat diet and sucrose induced type-2 diabetic rats	63
Angiopoietin inhibitors: A review on targeting tumor angiogenesis	63
Targeting Keap1/Nrf2/ARE signaling pathway in multiple sclerosis	62
No clinical benefit of high dose corticosteroid administration in patients with COVID-19: A preliminary report of a randomized clinical trial	62
MicroRNA interplay between hepatic stellate cell quiescence and activation	60
Quercetin loaded chitosan tripolyphosphate nanoparticles accelerated cutaneous wound healing in Wistar rats	59
A review on possible mechanistic insights of Nitazoxanide for repurposing in COVID-19	59
TRPM8 channels: A review of distribution and clinical role	58
The therapeutic efficacy of quercetin in combination with antiviral drugs in hospitalized COVID-19 patients: A randomized controlled trial	58
The footprint of kynurenine pathway in every cancer: a new target for chemotherapy	57
Pharmacodynamic effects and molecular mechanisms of lignans from Schisandra chinensis Turcz. (Baill.), a current review	56
Angiotensin-converting enzyme 2 (ACE2) receptor and SARS-CoV-2: Potential therapeutic targeting	55
NMDA and AMPA receptors dysregulation in Alzheimer's disease	55
Current herbal medicine as an alternative treatment in dentistry: In vitro, in vivo and clinical studies	54
AgRP/NPY and POMC neurons in the arcuate nucleus and their potential role in treatment of obesity	54
Endoplasmic reticulum as a potential therapeutic target for covid-19 infection management?	53
Statins and PCSK9 inhibitors: A new lipid-lowering therapy	52
Melatonin is a potential adjuvant to improve clinical outcomes in individuals with obesity and diabetes with coexistence of Covid-19	51
Dapagliflozin exerts anti-inflammatory effects via inhibition of LPS-induced TLR-4 overexpression and NF-κB activation in human endothelial cells and differentiated macrophages	51
Hesperetin ameliorates DSS-induced colitis by maintaining the epithelial barrier via blocking RIPK3/MLKL necroptosis signaling	51
Vascular disrupting agents in cancer therapy	50
Update on therapeutic approaches and emerging therapies for SARS-CoV-2 virus	50
The pharmacological activity of berberine, a review for liver protection	49
The natural (poly)phenols as modulators of microglia polarization via TLR4/NF-κB pathway exert anti-inflammatory activity in ischemic stroke	49
Integrative transcriptomics analysis of lung epithelial cells and identification of repurposable drug candidates for COVID-19	49
The role of CD44 in cancer chemoresistance: A concise review	49
Antiviral activity of chlorpromazine, fluphenazine, perphenazine, prochlorperazine, and thioridazine towards RNA-viruses. A review	48
The Egr-1/miR-15a-5p/GPX4 axis regulates ferroptosis in acute myocardial infarction	48
Unraveling the mechanism of arbidol binding and inhibition of SARS-CoV-2: Insights from atomistic simulations	48
Fisetin, potential flavonoid with multifarious targets for treating neurological disorders: An updated review	47
Silencing of HIF-1α/CD73 axis by siRNA-loaded TAT-chitosan-spion nanoparticles robustly blocks cancer cell progression	47
Modulation of the tumor microenvironment (TME) by melatonin	47
TGF-β-induced fibrosis: A review on the underlying mechanism and potential therapeutic strategies	47
Therapeutic treatment with Ibrutinib attenuates imiquimod-induced psoriasis-like inflammation in mice through downregulation of oxidative and inflammatory mediators in neutrophils and dendritic cells	47
Effects of sesamin on fatty acid and cholesterol metabolism, macrophage cholesterol homeostasis and serum lipid profile: A comprehensive review	46
MicroRNA-mediated autophagy regulation in cancer therapy: The role in chemoresistance/chemosensitivity	46
Mesenchymal stem cells as carriers for systemic delivery of oncolytic viruses	46
Advances in the possible treatment of COVID-19: A review.	46
A novel effect of Aprepitant: Protection for cisplatin-induced nephrotoxicity and hepatotoxicity	45
Inhibitory effect of melatonin on hypoxia-induced vasculogenic mimicry via suppressing epithelial-mesenchymal transition (EMT) in breast cancer stem cells.	45
Rosmarinic acid-induced apoptosis and cell cycle arrest in triple-negative breast cancer cells	44
Role of leukotriene pathway and montelukast in pulmonary and extrapulmonary manifestations of Covid-19: The enigmatic entity	43
Capsaicin: TRPV1-independent mechanisms and novel therapeutic possibilities	43
The PI3K/Akt/mTOR signaling pathway in gastric cancer; from oncogenic variations to the possibilities for pharmacologic interventions	43
Angiogenesis as a potential treatment strategy for rheumatoid arthritis	43
Vitamin D (VD3) antioxidative and anti-inflammatory activities: Peripheral and central effects	43
Daidzein ameliorates LPS-induced hepatocyte injury by inhibiting inflammation and oxidative stress	42
Ameliorating and protective effects mesalazine on ethanol-induced gastric ulcers in experimental rats	42

Doxorubicin chemotherapy-induced “chemo-brain”: Meta-analysis	42
Osthole inhibits ovarian carcinoma cells through LC3-mediated autophagy and GSDME-dependent pyroptosis except for apoptosis	42
PTEN: What we know of the function and regulation of this onco-suppressor factor in bladder cancer?	41
Thymosin beta 4 alleviates non-alcoholic fatty liver by inhibiting ferroptosis via up-regulation of GPX4	41
Molecular mechanisms of action of naringenin in chronic airway diseases	41
Pharmacological activation of Nrf2 promotes wound healing	41
MicroRNA-122 aggravates angiotensin II-mediated apoptosis and autophagy imbalance in rat aortic adventitial fibroblasts via the modulation of SIRT6-elabela-ACE2 signaling	41
Systemic and local delivery of mesenchymal stem cells for heart renovation: Challenges and innovations	40
Microglia and mast cells generate proinflammatory cytokines in the brain and worsen inflammatory state: Suppressor effect of IL-37	40
Imperatorin: A review of its pharmacology, toxicity and pharmacokinetics	40
4-Octyl itaconate protects against renal fibrosis via inhibiting TGF-β/Smad pathway, autophagy and reducing generation of reactive oxygen species	40
Ginsenoside Rg1 ameliorated experimental colitis by regulating the balance of M1/M2 macrophage polarization and the homeostasis of intestinal flora	40
Potential pharmacologic treatments for COVID-19 smell and taste loss: A comprehensive review	39
Targeting NLRP3 inflammasome as a promising approach for treatment of diabetic nephropathy: Preclinical evidences with therapeutic approaches	39
Promising targets of chrysin and daidzein in colorectal cancer: Amphiregulin, CXCL1, and MMP-9	39
Therapeutic applications of herbal/synthetic/bio-drug in oral cancer: An update	37
Anticancer natural medicines: An overview of cell signaling and other targets of anticancer phytochemicals	37
Quercetin overcomes colon cancer cells resistance to chemotherapy by inhibiting solute carrier family 1, member 5 transporter	37
Platycodin D alleviates liver fibrosis and activation of hepatic stellate cells by regulating JNK/c-JUN signal pathway	37
Atractylenolides, essential components of Atractylodes-based traditional herbal medicines: Antioxidant, anti-inflammatory and anticancer properties	37
Paeonol inhibits NLRP3 mediated inflammation in rat endothelial cells by elevating hyperlipidemic rats plasma exosomal miRNA-223	37
JAK/STAT pathway promotes the progression of diabetic kidney disease via autophagy in podocytes	36
Sacubitril/valsartan attenuates atrial electrical and structural remodelling in a rabbit model of atrial fibrillation	36
Neuroprotective potential of antihyperglycemic drug metformin in streptozocin-induced rat model of sporadic Alzheimer's disease	36
Effects of sacubitril/valsartan in patients with heart failure and chronic kidney disease: A meta-analysis	36
The prophylaxis and treatment potential of supplements for COVID-19	35
Allicin alleviates inflammation of diabetic macroangiopathy via the Nrf2 and NF-kB pathway	35
The effect of oleuropein on apoptotic pathway regulators in breast cancer cells	35
SNHG9, delivered by adipocyte-derived exosomes, alleviates inflammation and apoptosis of endothelial cells through suppressing TRADD expression	34
Parkinson's disease in women: Mechanisms underlying sex differences	34
Crosstalk between endoplasmic reticulum stress and oxidative stress: Focus on protein disulfide isomerase and endoplasmic reticulum oxidase 1	34
Artesunate attenuates 2, 4-dinitrochlorobenzene-induced atopic dermatitis by down-regulating Th17 cell responses in BALB/c mice	34
Functional and druggability analysis of the SARS-CoV-2 proteome	34
Current pharmacological treatments for SARS-COV-2: A narrative review	34
Therapeutic potential of MCC950, a specific inhibitor of NLRP3 inflammasome	34
Tissue distributions of antiviral drugs affect their capabilities of reducing viral loads in COVID-19 treatment	33
Toll-like receptor 4: A promising crossroads in the diagnosis and treatment of several pathologies	33
Coptisine ameliorates DSS-induced ulcerative colitis via improving intestinal barrier dysfunction and suppressing inflammatory response	33
PI3K/Akt/GSK-3β signal pathway is involved in P2X7 receptor-induced proliferation and EMT of colorectal cancer cells	33
Effect of spinal angiotensin-converting enzyme 2 activation on the formalin-induced nociceptive response in mice	33
AMP-activated protein kinase: An attractive therapeutic target for ischemia-reperfusion injury	33
Antidepressants’ effects on testosterone and estrogens: What do we know?	33
6-Gingerol attenuates microglia-mediated neuroinflammation and ischemic brain injuries through Akt-mTOR-STAT3 signaling pathway	33
Current trends and future perspectives of nanomedicine for the management of colon cancer	33
FoxO1 signaling as a therapeutic target for type 2 diabetes and obesity	33
Targeting the NRF2/KEAP1 pathway in cervical and endometrial cancers	33
TRP channels in cancer pain	33
Triptolide inhibits pancreatic cancer cell proliferation and migration via down-regulating PLAU based on network pharmacology of Tripterygium wilfordii Hook F	33
Aloe-emodin induces autophagy and apoptotic cell death in non-small cell lung cancer cells via Akt/mTOR and MAPK signaling	33
Current advances in stem cell-based therapies for hair regeneration	32
Role of JAK-STAT signaling in the pathogenic behavior of fibroblast-like synoviocytes in rheumatoid arthritis: Effect of the novel JAK inhibitor peficitinib	32
miRNA-29a reverses P-glycoprotein-mediated drug resistance and inhibits proliferation via up-regulation of PTEN in colon cancer cells	32
Mesenchymal stem cell-based nanoparticles and scaffolds in regenerative medicine	32
Investigation of beta-lactoglobulin derived bioactive peptides against SARS-CoV-2 (COVID-19): In silico analysis	32
The protective effect of metformin on mitochondrial dysfunction and endoplasmic reticulum stress in diabetic mice brain	32
Salvianolic acid B and sodium tanshinone II A sulfonate prevent pulmonary fibrosis through anti-inflammatory and anti-fibrotic process	32
Activation of the Nrf2/HO-1 signaling pathway by dimethyl fumarate ameliorates complete Freund's adjuvant-induced arthritis in rats	31
Berberrubine attenuates potassium oxonate- and hypoxanthine-induced hyperuricemia by regulating urate transporters and JAK2/STAT3 signaling pathway	31
Hypoxia-inducible factor-prolyl hydroxylase inhibitors for renal anemia in chronic kidney disease: Advantages and disadvantages	31
Syringaresinol attenuates sepsis-induced cardiac dysfunction by inhibiting inflammation and pyroptosis in mice	31
The mechanisms of baicalin ameliorate obesity and hyperlipidemia through a network pharmacology approach	31
Effect of chitosan oligosaccharide-conjugated selenium on improving immune function and blocking gastric cancer growth	31
Repositioning of histamine H1 receptor antagonist: Doxepin inhibits viropexis of SARS-CoV-2 Spike pseudovirus by blocking ACE2	31
Research progress in use of traditional Chinese medicine monomer for treatment of non-alcoholic fatty liver disease	31
Synthetic cathinones – From natural plant stimulant to new drug of abuse	31
Potential repurposing of the HDAC inhibitor valproic acid for patients with COVID-19	31
NADPH oxidase: A membrane-bound enzyme and its inhibitors in diabetic complications	31
Recent progress of antiviral therapy for coronavirus disease 2019	31
Oleanolic acid induces a dual agonist action on PPARγ/α and GLUT4 translocation: A pentacyclic triterpene for dyslipidemia and type 2 diabetes	30
Remote ischemic preconditioning-induced neuroprotection in cerebral ischemia-reperfusion injury: Preclinical evidence and mechanisms	30
Evaluation of artesunate for the treatment of adult T-cell leukemia/lymphoma	30
Effects of Hsp90 inhibitor on the RIP1-RIP3-MLKL pathway during the development of heart failure in mice	30
Gambogic acid potentiates gemcitabine induced anticancer activity in non-small cell lung cancer	30
Corticosteroid therapy is associated with the delay of SARS-CoV-2 clearance in COVID-19 patients	30
The anti-asthmatic potential of flavonol kaempferol in an experimental model of allergic airway inflammation	30
Use of steroids in COVID-19 patients: A meta-analysis	30
Role of RhoA-ROCK signaling in Parkinson's disease	30
Combined effects of berberine and evodiamine on colorectal cancer cells and cardiomyocytes in vitro	30
Should ACE2 be given a chance in COVID-19 therapeutics: A semi-systematic review of strategies enhancing ACE2	30
Virtual high throughput screening: Potential inhibitors for SARS-CoV-2 PLPRO and 3CLPRO proteases	30

A comprehensive review on pharmacology of efflux pumps and their inhibitors in antibiotic resistance	30
Ferroportin-mediated ferroptosis involved in new-onset atrial fibrillation with LPS-induced endotoxemia	30
Correlation between renin-angiotensin system and Severe Acute Respiratory Syndrome Coronavirus 2 infection: What do we know?	29
METTL3 regulates the malignancy of cervical cancer via post-transcriptional regulation of RAB2B	29
Bisdemethoxycurcumin attenuates cisplatin-induced renal injury through anti-apoptosis, anti-oxidant and anti-inflammatory	29
Association of ACE inhibitors and angiotensin type II blockers with ACE2 overexpression in COVID-19 comorbidities: A pathway-based analytical study	29
The effects of N-acetylcysteine on inflammatory and oxidative stress biomarkers: A systematic review and meta-analysis of controlled clinical trials	29
The role of VEGF in cancer-induced angiogenesis and research progress of drugs targeting VEGF	29
SARS-CoV-2 entry inhibitors by dual targeting TMPRSS2 and ACE2: An in silico drug repurposing study	29
Scutellarin ameliorates colitis-associated colorectal cancer by suppressing Wnt/β-catenin signaling cascade	28
Unravelling high-affinity binding compounds towards transmembrane protease serine 2 enzyme in treating SARS-CoV-2 infection using molecular modelling and docking studies	28
The effect of emodin on liver disease -- comprehensive advances in molecular mechanisms	28
Vitexin restores pancreatic β-cell function and insulin signaling through Nrf2 and NF-κB signaling pathways	28
The cannabinoid CB2 receptor agonist LY2828360 synergizes with morphine to suppress neuropathic nociception and attenuates morphine reward and physical dependence	28
Brief review on repurposed drugs and vaccines for possible treatment of COVID-19	28
Monotropein alleviates secondary liver injury in chronic colitis by regulating TLR4/NF-κB signaling and NLRP3 inflammasome	28
A research update on the therapeutic potential of rhein and its derivatives	28
Pharmacological inhibition of fatty acid-binding protein 4 alleviated kidney inflammation and fibrosis in hyperuricemic nephropathy	28
Complement and coagulation cascades pathway correlates with chemosensitivity and overall survival in patients with soft tissue sarcoma	28
Advancement in leishmaniasis diagnosis and therapeutics: An update	28
A novel MRGPRX2-targeting antagonistic DNA aptamer inhibits histamine release and prevents mast cell-mediated anaphylaxis	28
Abaloparatide: A review of preclinical and clinical studies	28
Ferroptosis triggered by dihydroartemisinin facilitates chlorin e6 induced photodynamic therapy against lung cancer through inhibiting GPX4 and enhancing ROS	28
Therapeutic Insights on Ferroptosis in Parkinson's disease	28
The effects of taurine supplementation on obesity, blood pressure and lipid profile: A meta-analysis of randomized controlled trials	27
ADMET profile and virtual screening of plant and microbial natural metabolites as SARS-CoV-2 S1 glycoprotein receptor binding domain and main protease inhibitors	27
Valeric acid lowers arterial blood pressure in rats	27
IL-6 promotes nuclear translocation of HIF-1α to aggravate chemoresistance of ovarian cancer cells	27
Anticancer effects and possible mechanisms of lycopene intervention on N-methylbenzylnitrosamine induced esophageal cancer in F344 rats based on PPARγ1	27
Role of pyroptosis in cancer and its therapeutic regulation	27
Resveratrol ameliorates renal damage by inhibiting oxidative stress-mediated apoptosis of podocytes in diabetic nephropathy	27
The emerging roles of HDACs and their therapeutic implications in cancer	27
Efficacy and safety of dihydroorotate dehydrogenase (DHODH) inhibitors “leflunomide” and “teriflunomide” in Covid-19: A narrative review	27
Therapeutic potential of quercetin in an animal model of PCOS: Possible involvement of AMPK/SIRT-1 axis	27
A comprehensive review on potential therapeutics interventions for COVID-19	27
Alamandine attenuates angiotensin II-induced vascular fibrosis via inhibiting p38 MAPK pathway	27
Celastrol attenuates inflammatory responses in adipose tissues and improves skeletal muscle mitochondrial functions in high fat diet-induced obese rats via upregulation of AMPK/SIRT1 signaling pathway	26
A ghrelin receptor antagonist reduces the ability of ghrelin, alcohol or amphetamine to induce a dopamine release in the ventral tegmental area and in nucleus accumbens shell in rats	26
Azithromycin: Immunomodulatory and antiviral properties for SARS-CoV-2 infection	26
Pinocembrin alleviates glucocorticoid-induced apoptosis by activating autophagy via suppressing the PI3K/Akt/mTOR pathway in osteocytes	26
Gabapentin attenuates intestinal inflammation: Role of PPAR-gamma receptor	26
Chrysin rescues rat myocardium from ischemia-reperfusion injury via PPAR-γ/Nrf2 activation	26
Arctiin protects rat heart against ischemia/reperfusion injury via a mechanism involving reduction of necroptosis	26
Xanthohumol attenuates isoprenaline-induced cardiac hypertrophy and fibrosis through regulating PTEN/AKT/mTOR pathway	26
Nanoformulated quinacrine regulates NECTIN-4 domain specific functions in cervical cancer stem cells	26
Dermatological applications of the flavonoid phloretin	26
Emodin prevents renal ischemia-reperfusion injury via suppression of CAMKII/DRP1-mediated mitochondrial fission	26
Berbamine induced AMPK activation regulates mTOR/SREBP-1c axis and Nrf2/ARE pathway to allay lipid accumulation and oxidative stress in steatotic HepG2 cells	26
6-Methoxyflavanone abates cisplatin-induced neuropathic pain apropos anti-inflammatory mechanisms: A behavioral and molecular simulation study	26
Regulation of PD-1 in T cells for cancer immunotherapy	26
Coronavirus diseases 2019: Current biological situation and potential therapeutic perspective	25
Nanocarriers for treatment of dermatological diseases: Principle, perspective and practices	25
Vitexin protects against ethanol-induced liver injury through Sirt1/p53 signaling pathway	25
Interferon therapy in patients with SARS, MERS, and COVID-19: A systematic review and meta-analysis of clinical studies	25
Luteolin impairs hypoxia adaptation and progression in human breast and colon cancer cells	25
Preventive effect of silymarin-loaded chitosan nanoparticles against global cerebral ischemia/reperfusion injury in rats	25
The effects of CGRP in vascular tissue - Classical vasodilation, shadowed effects and systemic dilemmas	25
Preclinical characterization of itacitinib (INCB039110), a novel selective inhibitor of JAK1, for the treatment of inflammatory diseases	25
Macrophage responses associated with COVID-19: A pharmacological perspective	25
Gypenoside XVII alleviates early diabetic retinopathy by regulating Müller cell apoptosis and autophagy in db/db mice	25
Pharmacological inhibition of poly (ADP-ribose) polymerase by olaparib, prevents acute lung injury associated cognitive deficits potentially through suppression of inflammatory response	25
Olmesartan attenuates type 2 diabetes-associated liver injury: Cross-talk of AGE/RAGE/JNK, STAT3/SCOS3 and RAS signaling pathways	25
GSK343, an inhibitor of EZH2, mitigates fibrosis and inflammation mediated by HIF-1α in human peritoneal mesothelial cells treated with high glucose	25
Breast milk MSCs upregulated β-cells PDX1, Ngn3, and PCNA expression via remodeling ER stress /inflammatory /apoptotic signaling pathways in type 1 diabetic rats	25
Dauricine alleviated secondary brain injury after intracerebral hemorrhage by upregulating GPX4 expression and inhibiting ferroptosis of nerve cells	24
Andrographolide protects against isoproterenol-induced myocardial infarction in rats through inhibition of L-type Ca2+ and increase of cardiac transient outward K+ currents	24
P2X7 receptor in multifaceted cellular signalling and its relevance as a potential therapeutic target in different diseases	24
Ferroptosis as a new therapeutic opportunity for nonviral liver disease	24
YC-1 potentiates the antitumor activity of gefitinib by inhibiting HIF-1α and promoting the endocytic trafficking and degradation of EGFR in gefitinib-resistant non-small-cell lung cancer cells	24
Melatonin and gastrointestinal cancers: Current evidence based on underlying signaling pathways	24
Naringin inhibits autophagy mediated by PI3K-Akt-mTOR pathway to ameliorate endothelial cell dysfunction induced by high glucose/high fat stress	24
Screening Malaria-box compounds to identify potential inhibitors against SARS-CoV-2 Mpro, using molecular docking and dynamics simulation studies	24
Regulatory effects of IL-1β in the interaction of GBM and tumor-associated monocyte through VCAM-1 and ICAM-1	24
Nectin cell adhesion molecule-4 (NECTIN-4): A potential target for cancer therapy	24
Combination of ponatinib with deferoxamine synergistically mitigates ischemic heart injury via simultaneous prevention of necroptosis and ferroptosis	24
Quercetin alleviates ferroptosis accompanied by reducing M1 macrophage polarization during neutrophilic airway inflammation	24
Coumarins derivatives and inflammation: Review of their effects on the inflammatory signaling pathways	24
Antidepressant mechanism of catalpol: Involvement of the PI3K/Akt/Nrf2/HO-1 signaling pathway in rat hippocampus	24
The involvement of epithelial-to-mesenchymal transition in doxorubicin resistance: Possible molecular targets	24
Apoptotic neurons and amyloid-beta clearance by phagocytosis in Alzheimer's disease: Pathological mechanisms and therapeutic outlooks	24
Can selective serotonin reuptake inhibitors have a neuroprotective effect during COVID-19?	23
Molecular mechanisms of bufadienolides and their novel strategies for cancer treatment	23
Heme is required for carbon monoxide activation of mitochondrial BKCa channel	23
Targeting autophagy to modulate hepatic ischemia/reperfusion injury: A comparative study between octreotide and melatonin as autophagy modulators through AMPK/PI3K/AKT/mTOR/ULK1 and Keap1/Nrf2 signali	23
Synergistic potential of dual andrographolide and melatonin targeting of metastatic colon cancer cells: Using the Chou-Talalay combination index method	23
Targeting EHMT2/ G9a for cancer therapy: Progress and perspective	23
Involvement of nitric oxide pathway in the anti-inflammatory effect of modafinil on indomethacin-, stress-, and ethanol -induced gastric mucosal injury in rat	23
MiR-375 inhibits the stemness of breast cancer cells by blocking the JAK2/STAT3 signaling	23
Phillygenin inhibited LPS-induced RAW 264.7 cell inflammation by NF-κB pathway	23
Gut microbiota modulation as a promising therapy with metformin in rats with non-alcoholic steatohepatitis: Role of LPS/TLR4 and autophagy pathways	23
Dihydroartemisinin inhibits the growth of pancreatic cells by inducing ferroptosis and activating antitumor immunity	23
Gamma delta (γδ) T cells in cancer immunotherapy; where it comes from, where it will go?	23
Iron oxide nanoparticles loaded with paclitaxel inhibits glioblastoma by enhancing autophagy-dependent ferroptosis pathway	23
Quercetin attenuates diabetic neuropathic pain by inhibiting mTOR/p70S6K pathway-mediated changes of synaptic morphology and synaptic protein levels in spinal dorsal horn of db/db mice	23
κ-opioid receptor activation promotes mitochondrial fusion and enhances myocardial resistance to ischemia and reperfusion injury via STAT3-OPA1 pathway	23