European Journal of Pharmacology

Article	Citations
Compound Z526 alleviates chemotherapy-induced cachectic muscle loss by ameliorating oxidative stress-driven protein metabolic imbalance and apoptosis	216
Novel combinatorial autophagy inhibition therapy for triple negative breast cancers	215
Editorial Board	144
Corrigendum to “Isopropyl 3-(3, 4-dihydroxyphenyl)-2-hydroxypropanoate protects lipopolysaccharide-induced acute lung injury in mice by attenuating pyroptosis” [Eur. J. Pharmacol. 5 (2023) 175545]	129
Autophagic inhibitor ROC-325 ameliorates glomerulosclerosis and podocyte injury via inhibiting autophagic flux in experimental FSGS mice	124
Comprehensive characterization of fatty acid oxidation in triple-negative breast cancer: Focus on biological roles and drug modulation	124
Combining brief recall and ketamine treatment prevents stress-primed methamphetamine memory reinstatement via heightening mPFC GABA activity	106
Inhibition of TRPC3 channels suppresses seizure susceptibility in the genetically-epilepsy prone rats	106
Suppression of hypoxia-induced CAV1 autophagic degradation enhances nanoalbumin-paclitaxel transcytosis and improves therapeutic activity in pancreatic cancer	104
Inhibiting PRMT1 protects against CoNV by regulating macrophages through the FGF2/PI3K/Akt pathway	87
Calycosin treats acute myocardial infarction via NLRP3 inflammasome: Bioinformatics, network pharmacology and experimental validation	84
TNF-alpha mediates airway hyperreactivity in silicotic mice: Effect of thalidomide treatment	84
Sitagliptin reduces cytokine-induced β-cell apoptosis in prediabetes: A six-month interventional study	83
A comprehensive review of targeting RAF kinase in cancer	82
Trametinib ameliorated Adriamycin-induced podocyte injury by inhibiting METTL3 modified m6A RCAN1 RNA methylation	82
Inverse agonism of lysophospholipids with cationic head groups at Gi-coupled receptor GPR82	79
Metformin alleviates glucolipotoxicity-induced pancreatic β cell ferroptosis through regulation of the GPX4/ACSL4 axis	74
Small molecule CGRP receptor antagonists for the preventive treatment of migraine: A review	72
Efficacy of the neurotensin receptor 1 analog PD149163 in modulation of the kidney inflammation: Inhibition of the nuclear factor kappa β signaling pathway and oxidative stress in endotoxemic mice	71
Toward precision dosing of linezolid in critical ill patients: efficiency and risk of thrombocytopenia analysis by population PKPD modeling and simulations	67
Resveratrol ameliorates cognitive impairment with improvement of gut microbiota, inflammation, neurogenesis, and synaptic proteins in a mouse model of Gulf War Illness	66
Low-intensity pulsed ultrasound prevents angiotensin II-induced aortic smooth muscle cell phenotypic switch via hampering miR-17-5p and enhancing PPAR-γ	64
Role of 11β-hydroxysteroid dehydrogenase type 1 inhibition in the antiobesity effect of J2H-1702 on adipocytes and a high-fat diet-induced NASH model	62
Dihydromyricetin restores mucus hypersecretion in Air–Liquid interface cultures in COPD by targeting the SRC-MAPK signaling pathway	60
Orofacial pain models induce impairment in spatial learning and working memory in rodents: A systematic review and meta-analysis	59

Arctiin attenuated NASH by inhibiting glycolysis and inflammation via FGFR2/CSF1R signaling	56
Ameliorative effect of GLP1 agonist on vascular calcification in normoglycemic aged rat aorta via miR34a/SIRT6/NRF2/HO-1 signalling pathway	56
Corosolic acid attenuates platelet-derived growth factor signaling in macrophages and smooth muscle cells of pulmonary arterial hypertension	55
Targeting eEF2K induces oxidative stress and sensitizes cancer cells to ferroptosis induction	55
IL-1 receptor-associated kinase family proteins: An overview of their role in liver disease	54
Neuroprotective effect of Perillyl alcohol in sporadic Alzheimer's disease in rats	53
Validating the temporal performance of genetic biomarkers in an animal model of recurrence/ non-recurrence myocardial infarction persuades by bioinformatics tools	52
Astragaloside IV mitigates cerebral ischaemia-reperfusion injury via inhibition of P62/Keap1/Nrf2 pathway-mediated ferroptosis	51
Inclusion of the in-chain sulfur in 3-thiaCTU increases the efficiency of mitochondrial targeting and cell killing by anticancer aryl-urea fatty acids	51
Nanomedicine: A great boon for cardiac regenerative medicine	51
Phloretin and Enalapril co-administration ameliorates hyperglycemia mediated exacerbation of myocardial injury in rats	50
PI3K/mTOR dual-inhibition with VS-5584 enhances anti-leukemic efficacy of ponatinib in blasts and Ph-negative LSCs of chronic myeloid leukemia	50
Tenacissoside H repressed the progression of glioblastoma by inhibiting the PI3K/Akt/mTOR signaling pathway	50
Isorhynchophylline ameliorates the progression of osteoarthritis by inhibiting the NF-κB pathway	50
Cardiovascular protective properties of the natural product eugenol	49
RNAi in psoriasis: A melodic exploration of miRNA, shRNA, and amiRNA with a spotlight on siRNA	49
The novel GLP-1 / GIP dual agonist DA3-CH is more effective than liraglutide in the MPTP mouse model of Parkinson's disease	49
Optimizing the structure of repurposed metformin can improve anti-cholinesterase and anti-amyloidogenic effects	49
The mitochondria-gut microbiota crosstalk – A novel frontier in cardiovascular diseases	48
Editorial Board	48
Melittin suppresses aerobic glycolysis by regulating HSF1/PDK3 to increase chemosensitivity of NSCLC	48
HSP90: A promising target for NSCLC treatments	47
Hydrogen sulfide ameliorates hypertension and vascular dysfunction induced by insulin resistance in rats by reducing oxidative stress and activating eNOS	46
Effects of chronic mirabegron treatment on metabolic and cardiovascular parameters as well as on atherosclerotic lesions of WHHL rabbits with high-fructose high-fat diet-induced insulin resistance.	46
Integrating network pharmacology, transcriptomics, and molecular simulation to reveal the mechanism of tert-butylhydroquinone for treating diabetic retinopathy	44
Amorphous selenium nanodots alleviate non-alcoholic fatty liver disease via activating VEGF receptor 1 to further inhibit phosphorylation of JNK/p38 MAPK pathways	44
Molecular interplay between EIF4 family and circular RNAs in cancer: Mechanisms and therapeutics	44
Nitisinone attenuates cartilage degeneration and subchondral osteoclastogenesis in osteoarthritis and concomitantly inhibits the cGAS/STING/NF-κB pathway	44
GPR146 regulates pulmonary vascular remodeling by promoting pulmonary artery smooth muscle cell proliferation through 5-lipoxygenase	43
3,3′-O-dimethylquercetin: A bi-functional vasodilator isolated from green propolis of the Caatinga Mimosa tenuiflora	43
Inhibition of intraflagellar transport protein-88 promotes epithelial-to-mesenchymal transition and reduces cardiac remodeling post-myocardial infarction	43
Eukaryotic elongation factor 2 kinase inhibitor, A484954 inhibits perivascular sympathetic nerve stimulation-induced vasoconstriction in isolated renal artery	43
Editorial Board	43
Corrigendum to “Guggulsterone inhibits migration and invasion through proteasomal and lysosomal degradation in human glioblastoma cells” [Eur. J. Pharmacol. 938 (2023) 175411]	43
Ginsenoside Rb1 promotes the activation of PPARα pathway via inhibiting FADD to ameliorate heart failure	41
The antidiabetic drug teneligliptin induces vasodilation via activation of PKG, Kv channels, and SERCA pumps in aortic smooth muscle	41
Cyclin-dependent kinase 5 inhibitor attenuates lipopolysaccharide-induced neuroinflammation through metabolic reprogramming	41
Ginsenoside Rg1 promotes fetal hemoglobin production in vitro: A potential therapeutic avenue for β-thalassemia	41
Antagonizing interleukin-5 receptor ameliorates dextran sulfate sodium-induced experimental colitis in mice through reducing NLRP3 inflammasome activation	41
Optimizing dose selection for doxorubicin-induced cardiotoxicity in mice: A comprehensive analysis of single and multiple-dose regimens	40
Significance of NMDA receptor-targeting compounds in neuropsychological disorders: An in-depth review	40
Ghrelin alleviates placental dysfunction by down-regulating NF-κB phosphorylation in LPS-induced rat model of preeclampsia	40
Inhibition of inducible nitric oxide synthase (iNOS) alleviates thoracic aortic aneurysm by regulating mitochondrial dynamics	39
Long non-coding RNA MALAT1 modulates myocardial ischemia-reperfusion injury through the PI3K/Akt/eNOS pathway by sponging miRNA-133a-3p to target IGF1R expression	39
Deciphering TGF-β1's role in drug resistance and leveraging plant bioactives for cancer therapy	39
Suppression of hippocampal GABAergic transmission impairs memory in rodent models of Alzheimer's disease	39
Extracellular vesicles as multiorgan crosstalk mediators in cardiovascular diseases: emerging biomarkers and therapeutic targets	39
Phosphodiesterase-1 inhibitor modulates Ca2+ regulation in sirtuin 1-deficient mouse cardiomyocytes	39
Hesperetin ameliorates spinal cord injury in rats through suppressing apoptosis, oxidative stress and inflammatory response	39
Characterisation of bis(4-aminoquinoline)s as α1A adrenoceptor allosteric modulators	39

Risperidone impedes glutamate excitotoxicity in a valproic acid rat model of autism: Role of ADAR2 in AMPA GluA2 RNA editing	38
Dopamine agonists versus levodopa monotherapy in early Parkinson's disease for the potential risks of motor complications: A network meta-analysis	37
Protein detection and localization of the non-selective cation channel TRPC6 in the human heart	37
Advancing health care via artificial intelligence: From concept to clinic	37
Evodiamine impairs HIF1A histone lactylation to inhibit Sema3A-mediated angiogenesis and PD-L1 by inducing ferroptosis in prostate cancer	37
Small-molecule targeting PKM2 provides a molecular basis of lactylation-dependent fibroblast-like synoviocytes proliferation inhibition against rheumatoid arthritis	37
Early Sacubitril/valsartan Therapy Reduces Ventricular Remodeling and Cardiac Events in Patients with Acute Anterior Myocardial Infarction	37
Effects of oleanolic acid and ursolic acid on depression-like behaviors induced by maternal separation in mice	37
Protective effect of 5,6,7,8-Tetrahydroxyflavone on high altitude cerebral edema in rats	36
Vanin1 (VNN1) in chronic diseases: Future directions for targeted therapy	36
Preventive effects of (−) epicatechin on tachycardia, cardiac hypertrophy, and nuclear factor- κB inflammatory signaling pathway in isoproterenol-induced myocardial infarcted rats	36
Dehydrocostuslactone attenuated oxygen and glucose deprivation/reperfusion-induced PC12 cell injury through inhibition of apoptosis and autophagy by activating the PI3K/AKT/mTOR pathway	36
Abaloparatide: A review of preclinical and clinical studies	36
Manzamine A: A promising marine-derived cancer therapeutic for multi-targeted interactions with E2F8, SIX1, AR, GSK-3β, and V-ATPase - A systematic review	35
High-throughput screening of the natural STK11 agonist dauricine: A biphenylisoquinoline alkaloid exerting anti-NSCLC effects and reversing gefitinib resistance	35
Molecular mechanism and therapeutic significance of dihydromyricetin in nonalcoholic fatty liver disease	35
Teneligliptin, a DPP4 inhibitor protects dopaminergic neurons in PD models via inhibiting of oxidative stress and ferroptosis	35
Editorial Board	35
Tumoral EIF4EBP1 regulates the crosstalk between tumor-associated macrophages and tumor cells in MRTK	35
Cycloheptylprodigiosin from marine bacterium Spartinivicinus ruber MCCC 1K03745T induces a novel form of cell death characterized by Golgi disruption and enhanced secretion of cathepsin D in non-small	34
Lapatinib ditosylate rescues motor deficits in rotenone-intoxicated rats: Potential repurposing of anti-cancer drug as a disease-modifying agent in Parkinson's disease	34
Kurarinone induced p53-independent G0/G1 cell cycle arrest by degradation of K-RAS via WDR76 in human colorectal cancer cells	34
Dioscin alleviates lung ischemia/reperfusion injury by regulating FXR-mediated oxidative stress, apoptosis, and inflammation	34
Naproxen as a potential candidate for promoting rivastigmine anti-Alzheimer activity against aluminum chloride-prompted Alzheimer's-like disease in rats; neurogenesis and apoptosis modulation as a pos	34
Cancer-associated fibroblasts (CAFs) and tumor-associated macrophages (TAMs); where do they stand in tumorigenesis and how they can change the face of cancer therapy?	34
Potential of Orlistat to induce apoptotic and antiangiogenic effects as well as inhibition of fatty acid synthesis in breast cancer cells	34
Metabolic reprogramming of glutamine involved in tumorigenesis, multidrug resistance and tumor immunity	34
Alternative role of glucagon-like Peptide-1 receptor agonists in neurodegenerative diseases	34
Drug repurposing: An emerging strategy in alleviating skin cancer	34
Hypoxia-inducible factor-1: Regulatory mechanisms and drug therapy in myocardial infarction	34
LRP1 at the crossroads of Parkinson's and Alzheimer's: Divergent roles in α-synuclein and amyloid pathology	33
Inhibition of abnormally activated HIF-1α-GLUT1/3-glycolysis pathway enhances the sensitivity of hepatocellular carcinoma to 5-caffeoylquinic acid and its derivatives	33
Editorial Board	33
Ginkgolide A alleviates cardiac remodeling in mice with myocardial infarction via binding to matrix metalloproteinase-9 to attenuate inflammation	33
Sodium nitrite induces tolerance in the mouse aorta: Involvement of the renin-angiotensin system, nitric oxide synthase, and reactive oxygen species	33
Inhibition of CHIT1 as a novel therapeutic approach in idiopathic pulmonary fibrosis	33
Comparative efficacy and acceptability of drug treatments for Parkinson’s disease with depression: A systematic review with network meta-analysis	33
Hepatitis B Virus X Protein promotes VWF-mediated HCC progression through ST8SIA6-AS1/miR-3150b-3p/ASCL1 axis	33
CRISPR/Cas9-based multiplex genome editing of BCL11A and HBG efficiently induces fetal hemoglobin expression	32
Transcription factor MEOX1 accelerates pulmonary fibrosis by regulating mitophagy and senescence	32
Poncirin ameliorates cardiac ischemia-reperfusion injury by activating PI3K/AKT/PGC-1α signaling	32
SAP30BP aggravates mitochondrial-related ferroptosis in diabetic cardiomyopathy by regulating MFN2-ACSL4 axis	32
Effects of intranasal azithromycin on features of cigarette smoke-induced lung inflammation	32
Anti-cancer impact of Hypericin in B-CPAP cells: Extrinsic caspase dependent apoptosis induction and metastasis obstruction	31
Recent trends in diabetic wound healing with nanofibrous scaffolds	31
A novel Toll-like receptor 7/8–specific antagonist E6742 ameliorates clinically relevant disease parameters in murine models of lupus	31
Astragaloside IV protects against C/EBP homologous protein-mediated apoptosis in oxidized low-density lipoprotein-treated macrophages by promoting autophagy	31
Corrigendum to “Protective effects of cortex fraxini coumarines against oxonate-induced hyperuricemia and renal dysfunction in mice” [Eur. J. Pharmacol. 666 (2011) 196–204]	31
Succinate level is increased and succinate dehydrogenase exerts forward and reverse catalytic activities in lipopolysaccharides-stimulated cardiac tissue: The protective role of dimethyl malonate	31
Pregabalin can interact synergistically with Kv7 channel openers to exert antinociception in mice	31
LncRNAS—modulators of neurovascular units in diabetic retinopathy	31
Editorial Board	31
Transcription factor EB protects against endoplasmic reticulum stress in human coronary artery endothelial cells	31
Stabilization of mitochondrial function by chlorogenic acid protects against kainic acid-induced seizures and neuronal cell death in rats	31
Trilobatin alleviates non-alcoholic fatty liver disease in high-fat diet plus streptozotocin-induced diabetic mice by suppressing NLRP3 inflammasome activation	31
Alpha1B-adreneroceptor is involved in norepinephrine-induced pulmonary artery smooth muscle cell proliferation via p38 signaling	30
The key roles of non-coding RNAs in the pathophysiology of hypertension	30
Effects of the serotonin 5-HT1B receptor agonist CP 94253 on the locomotor activity and body temperature of preweanling and adult male and female rats	30
LncRNA DANCR deficiency promotes high glucose-induced endothelial to mesenchymal transition in cardiac microvascular cells via the FoxO1/DDAH1/ADMA signaling pathway	29
Effects of cannabinoid agonists and antagonists in male rats discriminating the synthetic cannabinoid AM2201	29
Galangin ameliorates osteoarthritis progression by attenuating extracellular matrix degradation in chondrocytes via the activation of PRELP expression	29
A BET inhibitor, NHWD-870, can downregulate dendritic cells maturation via the IRF7-mediated signaling pathway to ameliorate imiquimod-induced psoriasis-like murine skin inflammation	29
Aucubin supplementation alleviate diabetes induced-disruption of blood-testis barrier and testicular damage via stabilizing cell junction integrity	29
Anti-pancreatic lipase and anti-adipogenic effects of 5,7,3′,4′,5′-pentamethoxy and 6,2′,4′-trimethoxy flavone - An in vitro study	28
Research progress on the role of orphan receptor GPR139 in neuropsychiatric behaviours	28
Trigeminal neuropathic pain reduces 50-kHz ultrasonic vocalizations in rats, which are restored by analgesic drugs	28
Hypoxia activates GPR146 which participates in pulmonary vascular remodeling by promoting pyroptosis of pulmonary artery endothelial cells	28
Repositioning of Montelukast to inhibit proliferation of mutated KRAS pancreatic cancer through a novel mechanism that interfere the binding between KRAS and GTP/GDP	28
Face validation and pharmacologic analysis of Sik3 mutant mouse as a possible model of idiopathic hypersomnia	28
Protective effects of 5(S)-5-carboxystrictosidine on myocardial ischemia-reperfusion injury through activation of mitochondrial KATP channels	28
Curcumin nicotinate decreases serum LDL cholesterol through LDL receptor-mediated mechanism	28
Influence of adrenalectomy on the gut microbiome and MDMA-induced hyperthermia	28
Dankasterone A induces prostate cancer cell death by inducing oxidative stress	28
Mutation of valine 53 at the interface between extracellular and transmembrane domains of the β2 principal subunit affects the GABAA receptor gating	28
Identification of novel SIRT1 up-regulators using a cell-based high-throughput screening assay	28
Human umbilical cord-derived stem cell sheets improve left ventricular function in rat models of ischemic heart failure	27
Recent advancements in targeting the immune system to treat hypertension	27
Demyelination in cuprizone mice is ameliorated by calycosin mediated through astrocyte Nrf2 signaling pathway	27
Crosstalk between endothelial cells with a non-canonical EndoMT phenotype and cardiomyocytes/fibroblasts via IGFBP5 aggravates TAC-induced cardiac dysfunction	27
Sustained AT1R stimulation induces upregulation of growth factors in human cardiac fibroblasts via Gαq/TGF-β/ERK signaling that influences myocyte hypertrophy	27

Up-regulated ITGB4 promotes hepatocellular carcinoma metastasis by activating hypoxia-mediated glycolysis and cancer-associated fibroblasts	26
Potential role of remimazolam in alleviating bone cancer pain in mice via modulation of translocator protein in spinal astrocytes	26
Pirfenidone improves voiding function by suppressing bladder fibrosis in underactive bladder rats	26
CYT997 induces apoptosis in hypertrophic scar fibroblasts and inhibits scar formation	26
Advanced dressings based on novel biological targets for diabetic wound healing: A review	26
SGLT2 inhibitor dapagliflozin mitigates skeletal muscle pathology by modulating key proteins involved in glucose and ion homeostasis in an animal model of heart failure	26
Sophoricoside ameliorates cerebral ischemia-reperfusion injury dependent on activating AMPK	26
Biochanin A inhibits excitotoxicity-triggered ferroptosis in hippocampal neurons	26
Targeting endothelial cells: A novel strategy for pulmonary fibrosis treatment	26
Salidroside attenuates high altitude hypobaric hypoxia-induced brain injury in mice via inhibiting NF-κB/NLRP3 pathway	25
Tryptanthrin impairs platelet function and thrombus formation by reducing Gp1bα expression	25
Targets, trials and tribulations in Alzheimer therapeutics	25
Quercetin and piperine enriched nanostructured lipid carriers (NLCs) to improve apoptosis in oral squamous cellular carcinoma (FaDu cells) with improved biodistribution profile	25
Antidepressant-like effect of sodium orthovanadate in a mouse model of chronic unpredictable mild stress	25
Ankrd1 regulates endogenous cardiac regeneration in mice by modulating cyclin D1	25
Sodium houttuyfonate protects against cardiac injury by regulating cardiac energy metabolism in diabetic rats	25
Involvement of ferroptosis in eribulin-induced cytotoxicity in ovarian clear cell carcinoma	25
Oncolytic viruses as emerging therapy against cancers including Oncovirus-induced cancers	25
Dihydrotanshinone I improves cardiac function by promoting lymphangiogenesis after myocardial ischemia-reperfusion injury	25
Next generation Bruton's tyrosine kinase inhibitors – characterization of in vitro potency and selectivity	25
Ginsenoside Rd attenuates myocardial ischemia injury through improving mitochondrial biogenesis via WNT5A/Ca2+ pathways	25
In vivo and In vitro Crosstalk Among CBD, Aβ, and endocannabinoid system enzymes and receptors	24
Cancer chemotherapy resistance: Mechanisms and recent breakthrough in targeted drug delivery	24
Inhibiting 5-HT2C receptor in the hippocampus rescues EphB2-dependent memory impairment in mice	24
PAI-1 siRNA-loaded biomimetic nanoparticles for ameliorating diminished ovarian reserve and inhibiting ovarian fibrosis	24
A positive allosteric modulator of α7 nicotinic receptor reduces levodopa-induced dyskinesias in hemi-parkinsonian mice	24
Genkwanin blocks the interaction between phosphorylated JNK and NFATc1 to promote osteogenic differentiation and collagen Ⅰ α1 production	24
Pirfenidone and nintedanib attenuates pulmonary artery endothelial and smooth muscle cells transformations induced by IL-11	24
Tulipalin A suppressed the pro-inflammatory polarization of M1 macrophage and mitigated the acute lung injury in mice via interference DNA binding activity of NF-κB	24
GW501516 facilitated tumor immune escape by inhibiting phagocytosis	24
Cuproptosis induced by curcumin interfering with proliferation and energy metabolism in colorectal cancer: 3D tumor model and computational simulations reveal curcumin inhibition of HSPD1 and CALCOCO2	24
Astragalus polysaccharide attenuates bleomycin-induced pulmonary fibrosis by inhibiting TLR4/ NF-κB signaling pathway and regulating gut microbiota	24
Valdecoxib blocks rat TRPV2 channels	24
Nonadditive transcriptional change analysis identifies regulators for ginsenoside Rg3 to alleviate synergistic cytokine production in TLR2/3 dual-stimulated macrophages	24
Discovery of cinnamoyl–flavonoid hybrid derivatives as inhibitors of SARS-CoV-2 Mpro and anti-inflammatory agents: Experimental and in silico insights into their efficacy against lipopolysaccharide-in	24
Imperatorin attenuates CCl4-induced cirrhosis and portal hypertension by improving vascular remodeling and profibrogenic pathways	24
Evaluation of the anticancer activity of singly and doubly modified analogues of C20-epi-salinomycin	23
Simultaneous nanocarrier-mediated delivery of siRNAs and chemotherapeutic agents in cancer therapy and diagnosis: Recent advances	23
Brusatol modulates the Nrf2/GCLC pathway to enhance ferroptosis in the treatment of oral squamous cell carcinoma	23
Effects of 101BHG-D01, a novel M receptor antagonism, on allergic rhinitis in animal models and its mechanism	23
Analysis of differences in dupilumab-associated adverse drug event signals between children and adults based on the FAERS database	23
LncRNA MEG3 reverses CCl4-induced liver fibrosis by targeting NLRC5	23
A novel nordihydroguaiaretic acid analog, compound 3a, alleviates acute lung injury by exerting antiapoptotic and antiinflammatory effects	23
Investigation of the effects of losartan and captopril on rotenone-induced inflammation via TLR4/NLRP3 pathway: An integrative in vitro and in silico study	23
Luteolin alleviates hyposalivation by upregulating AQP5 through binding to estrogen receptor β and potentiating the saliva secretion signaling pathway	23
A review of nardosinone for pharmacological activities	23
Dose-dependent opposite effects of nortriptyline on affective-like behavior in adolescent rats: Comparison with adult rats	23
Retraction notice to “Apoptotic cell death: A possible key event in mediating the in vitro anti-proliferative effect of a novel copper(II) complex, [Cu(4-Mecdoa) (phen)2] (phen = phenanthroline, 4-Mec	23
Corrigendum to “Combination therapy with citalopram, bupropion, and lithium for the amelioration of the depressive-related effects induced by dexamethasone in male mice” [Eur. J. Pharmacol. 1002 (2025	23
Koumine alters immune barrier function by targeting TGFβ-mediated collagen deposition in gastric cancer	23
Mechanisms underlying the efficacy and limitation of dopa and tetrahydrobiopterin therapies for the deficiency of GTP cyclohydrolase 1 revealed in a novel mouse model	22
Purinergic ionotropic P2X7 and metabotropic glutamate mGlu5 receptors crosstalk influences pro-inflammatory conditions in microglia	22
Overexpressed mitogen-and stress-activated protein kinase 1 promotes the resistance of cytarabine in acute myeloid leukemia through brahma related gene 1-mediated upregulation of heme oxygenase-1	22
Curcumol suppresses endothelial-to-mesenchymal transition via inhibiting the AKT/GSK3β signaling pathway and alleviates pulmonary arterial hypertension in rats	22
Dehydrozingerone alleviates pulmonary fibrosis via inhibition of inflammation and epithelial-mesenchymal transition by regulating the Wnt/β-catenin pathway	22
Synthesis of 2-(2-(4-thioxo-3H-1,2-dithiole-5-yl) phenoxy)ethyl)isoindole-1,3-thione, a novel hydrogen sulfide-releasing phthalimide hybrid, and evaluation of its activity in models of inflammatory pa	22
Biopharmaceuticals against substance use disorders – Present and future	22
Effects of proprotein convertase subtilisin-kexin type 9 inhibitors on inflammatory and hemostatic parameters in post myocardial infarction patients	22
Editorial Board	22
Editorial Board	22
Repurposing old molecules for new indications: Defining pillars of success from lessons in the past	22
Development of a novel Poly (I:C)-induced murine model with accelerated lupus nephritis and examination of the therapeutic effects of mycophenolate mofetil and a cathepsin S inhibitor	22
Comparison of the effects of peficitinib and tofacitinib in the adjuvant-induced arthritis rat model	22
Complementary effects of dapagliflozin and lobeglitazone on metabolism in a diet-induced obese mouse model	22
Hinokitiol protects gastric injury from ethanol exposure via its iron sequestration capacity	22
lncRNA BBOX1-AS1 silencing inhibits esophageal squamous cell cancer progression by promoting ferroptosis via miR-513a-3p/SLC7A11 axis	22
Desmopressin enhances random-pattern skin flap survival in rats: Possible role of vasopressin Type-1a and 2 receptors	22
Editorial Board	22
Michael acceptor-dependent pro-oxidative intervention against angiogenesis by [6]-dehydroshogaol, a pungent constituent of ginger	22
Cyanidin-3-O-glucoside and its derivative vitisin A alleviate androgenetic alopecia by exerting anti-androgen effect and inhibiting dermal papilla cell apoptosis	22
Anticancer activity and metabolic alteration in colon and prostate cancer cells by novel moxifloxacin conjugates with fatty acids	22
MCPIP1 regulates focal adhesion kinase and Rho GTPase-dependent migration in clear cell renal cell carcinoma	22
Synthetic flavokawain analog (E)-1-(2′-hydroxy-4′,6′-dimethoxyphenyl)-3-(3-methoxy-4-(3-morpholinopropoxy)phenyl)prop-2-en-1-one (FK-morph) effectively regresses endometriotic implants in rats	22
Molsidomine ameliorates DEXA-induced insulin resistance: Involvement of HMGB1/JAK1/STAT3 signaling pathway	21
Emerging therapeutic avenues in cardiac amyloidosis	21
New insights on the differential interaction of sulfiredoxin with members of the peroxiredoxin family revealed by protein-protein docking and experimental studies	21
Gabapentin attenuates cardiac remodeling after myocardial infarction by inhibiting M1 macrophage polarization through the peroxisome proliferator-activated receptor-γ pathway	21
Targeting TRPs in autophagy regulation and human diseases	21
Phosphatidic acid as a cofactor of mTORC1 in platinum-based chemoresistance: Mechanisms and therapeutic potential	21
Functional studies and molecular dynamics reveal BPP-BrachyNH2-induced relaxation in male rat small mesenteric arteries via binding to argininosuccinate synthase	21
Modulation of SIRT6 related signaling pathways of p-AKT/mTOR and NRF2/HO-1 by memantine contributes to curbing the progression of tamoxifen/HFD-induced MASH in rats	21
A peripherally restricted cannabinoid-1 receptor inverse agonist promotes insulin secretion and protects from cytokine toxicity in human pancreatic islets	21
IGF2/IGF2R/Sting signaling as a therapeutic target in DSS-induced ulcerative colitis	21
Protective effects of atorvastatin on testicular dysfunction and reduced sperm quality induced by high-fat diet in mice: The inhibitory mechanism of oxidative stress	21
A combination of peripherally restricted CB1 and CB2 cannabinoid receptor agonists reduces bladder afferent sensitisation in cystitis	21
Oleocanthalic acid improves MASH features via a NOX1-dependent mechanism	21
The soluble guanylate cyclase (sGC) stimulator vericiguat inhibits platelet activation and thrombosis	21
The endocrine disruptor vinclozolin causes endothelial injury via eNOS/Nox4/IRE1α signaling	21
Exploring the mechanism of α-Bisabolol in the treatment of psoriasis based on network pharmacology and experimental validation	21
Synergism of small molecules targeting VDAC with sorafenib, regorafenib or lenvatinib on hepatocarcinoma cell proliferation and survival	21
Improving chimeric antigen receptor T-cell therapies by using artificial intelligence and internet of things technologies: A narrative review	21
Therapeutic effects of finerenone and exenatide on diabetes-induced heart failure: A combined approach targeting inflammation and oxidative stress	21
Combination therapy with cetirizine and anti-PD-1 antibody suppresses colitis-induced colon tumor formation in mice	21
Mendelian randomization analysis with the GEO database: Exploring the molecular mechanism underlying insulin therapy for perioperative neurocognitive disorders	21
Harringtonine metabolites: 5'-de-O-methylharringtonine and cephalotaxine, targeting spike protein and TMPRSS2 to double block membrane fusion of SARS-CoV-2 and its variants	21