OOIR: Observatory of International Research

Papers

(The H4-Index of European Journal of Pharmacology is 43. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
1, 8-cineole protects against ISO-induced heart failure by inhibiting oxidative stress and ER stress in vitro and in vivo	219
High urea induces anxiety disorders associated with chronic kidney disease by promoting abnormal proliferation of OPC in amygdala	190
Sacubitril/valsartan reduces susceptibility to atrial fibrillation by improving atrial remodeling in spontaneously hypertensive rats	136
Discovery of a highly potent kinase inhibitor capable of overcoming multiple imatinib-resistant ABL mutants for chronic myeloid leukemia (CML)	136
Peptides originally derived from Chilobrachys jingzhao tarantula venom possess beneficial effects on pancreatic beta cell health and function	96
The pathogenesis of depression: Roles of connexin 43-based gap junctions and inflammation	94
Luteolin alleviates diabetic cardiac injury related to inhibiting SHP2/STAT3 pathway	89
Students’ perspective on the Dutch National Pharmacotherapy Assessment, a national survey study among final-year medical students	89
Role of 11β-hydroxysteroid dehydrogenase type 1 inhibition in the antiobesity effect of J2H-1702 on adipocytes and a high-fat diet-induced NASH model	84
Retraction notice to “Tanshinone IIA protects hypoxia-induced injury by preventing microRNA-28 up-regulation in PC-12 cells” [Eur. J. Pharmacol. 854 (2019) 265–271]	83
ACSL family: The regulatory mechanisms and therapeutic implications in cancer	80
Losartan and metabolite EXP3179 activate endothelial function without lowering blood pressure in AT2 receptor KO mice	80
Targeting beta-catenin signaling for prevention of colorectal cancer – Nutraceutical, drug, and dietary options	77
Downregulation of PDCD4 through STAT3/ATF6/autophagy mediates MIF-induced PASMCs proliferation/migration and vascular remodeling	75
Kinsenoside mitigates myocardial ischemia/reperfusion-induced ferroptosis via activation of the Akt/Nrf2/HO-1 pathway	71
Icariside II mitigates myocardial infarction by balancing mitochondrial dynamics and reducing oxidative stress through the activation of Nrf2/SIRT3 signaling pathway	70
CT2-3 induces cell cycle arrest and apoptosis in rheumatoid arthritis fibroblast-like synoviocytes through regulating PI3K/AKT pathway	68
Theaflavine inhibits hepatic stellate cell activation by modulating the PKA/LKB1/AMPK/GSK3β cascade and subsequently enhancing Nrf2 signaling	67
Effects of oleanolic acid and ursolic acid on depression-like behaviors induced by maternal separation in mice	67
Proteomic analysis reveals that ACSL4 activation during reflux esophagitis contributes to ferroptosis-mediated esophageal mucosal damage	65
Effects of sacubitril-valsartan on aging-related cardiac dysfunction	65
Abaloparatide: A review of preclinical and clinical studies	63
The mechanism of the imbalance between proliferation and ferroptosis in pulmonary artery smooth muscle cells based on the activation of SLC7A11	58
Inhibiting PRMT1 protects against CoNV by regulating macrophages through the FGF2/PI3K/Akt pathway	56
Cerebroprotein hydrolysate-I ameliorates cognitive dysfunction in APP/PS1 mice by inhibiting ferroptosis via the p53/SAT1/ALOX15 signalling pathway	55

Arctigenin, an anti-tumor agent; a cutting-edge topic and up-to-the-minute approach in cancer treatment	55
The mechanism by which ATP regulates alcoholic steatohepatitis through P2X4 and CD39	54
Application and advantages of zebrafish model in the study of neurovascular unit	54
Hypoxia-induced TRPM7 promotes glycolytic metabolism and progression in hepatocellular carcinoma	53
Spinal dopaminergic D1-and D2-like receptors have a sex-dependent effect in an experimental model of fibromyalgia	52
Propionate ameliorates diabetes-induced neurological dysfunction through regulating the PI3K/Akt/eNOS signaling pathway	50
Melanocortin receptor-4 mediates the anorectic effect induced by the nucleus tractus solitarius injection of glucagon-like Peptide-2 in fasted rats	50
Carbon monoxide-releasing molecule-2 ameliorates postresuscitation myocardial dysfunction in rat via mitochondrial-mediated apoptosis pathway and the regulation of mitochondrial dynamics	49
Licochalcone A induces G2/M phase arrest and apoptosis via regulating p53 pathways in esophageal cancer: In-vitro and in-vivo study	49
Catalpol ameliorates LPS-induced inflammatory response by activating AMPK/mTOR signaling pathway in rat intestinal epithelial cells	48
Sis-25, a meroditerpenoid derivative with a cyclobutane scaffold, inhibits activated T cell proliferation by targeting GSK3β in vitro and in vivo	48
Non-coding RNAs and exosomal ncRNAs in multiple myeloma: An emphasis on molecular pathways	47
Propranolol modulation of tetrodotoxin-resistant Na+ channels in dural afferent neurons	47
Dexmedetomidine inhibits LPS-induced inflammatory responses through peroxisome proliferator-activated receptor gamma (PPARγ) activation following binding to α2 adrenoceptors	47
Icariin arrests cell cycle progression and induces cell apoptosis through the mitochondrial pathway in human fibroblast-like synoviocytes	46
Crosstalk relationship between adiponectin receptors, PPAR-γ and α-adrenoceptors in renal vasculature of diabetic WKYs	44
Tenacissoside H repressed the progression of glioblastoma by inhibiting the PI3K/Akt/mTOR signaling pathway	43
Curcumin nicotinate increases LDL cholesterol uptake in hepatocytes through IDOL/LDL-R pathway regulation	43