OOIR: Observatory of International Research

Papers

(The H4-Index of European Journal of Pharmacology is 49. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Macrophage M1/M2 polarization	874
Alzheimer's disease: Recent treatment strategies	290
Treatment for COVID-19: An overview	213
COVID-19 vaccine: A recent update in pipeline vaccines, their design and development strategies	182
siRNA: Mechanism of action, challenges, and therapeutic approaches	143
Ferroptosis involves in renal tubular cell death in diabetic nephropathy	112
ACSL family: The regulatory mechanisms and therapeutic implications in cancer	105
Dexamethasone: Therapeutic potential, risks, and future projection during COVID-19 pandemic	104
Naringenin and naringin in cardiovascular disease prevention: A preclinical review	102
Geniposide alleviates diabetic nephropathy of mice through AMPK/SIRT1/NF-κB pathway	92
Flavonols as potential antiviral drugs targeting SARS-CoV-2 proteases (3CLpro and PLpro), spike protein, RNA-dependent RNA polymerase (RdRp) and angiotensin-converting enzyme II receptor (ACE2)	91
In silico pharmacokinetic and molecular docking studies of natural flavonoids and synthetic indole chalcones against essential proteins of SARS-CoV-2	90
Application of methylene blue -vitamin C –N-acetyl cysteine for treatment of critically ill COVID-19 patients, report of a phase-I clinical trial	89
Current advancements and future perspectives of immunotherapy in colorectal cancer research	88
Virology, pathogenesis, diagnosis and in-line treatment of COVID-19	85
COVID-19: A review of the proposed pharmacological treatments	84
A review of potential suggested drugs for coronavirus disease (COVID-19) treatment	83
Remdesivir for treatment of COVID-19; an updated systematic review and meta-analysis	77
Possibility of magnesium supplementation for supportive treatment in patients with COVID-19	76
Curcumin, a traditional spice component, can hold the promise against COVID-19?	75
Neuroprotective role of polyphenols against oxidative stress-mediated neurodegeneration	74
Role of natural products for the treatment of Alzheimer's disease	73
Positive allosteric modulation of GABAA receptors by a novel antiepileptic drug cenobamate	68
In silico molecular docking analysis for repurposing therapeutics against multiple proteins from SARS-CoV-2	67
Targeting STAT3 in cancer and autoimmune diseases	67

Astragalus polysaccharide prevents ferroptosis in a murine model of experimental colitis and human Caco-2 cells via inhibiting NRF2/HO-1 pathway	66
Empagliflozin ameliorates endothelial dysfunction and suppresses atherogenesis in diabetic apolipoprotein E-deficient mice	64
Beta-sitosterol attenuates insulin resistance in adipose tissue via IRS-1/Akt mediated insulin signaling in high fat diet and sucrose induced type-2 diabetic rats	63
Angiopoietin inhibitors: A review on targeting tumor angiogenesis	63
Targeting Keap1/Nrf2/ARE signaling pathway in multiple sclerosis	62
No clinical benefit of high dose corticosteroid administration in patients with COVID-19: A preliminary report of a randomized clinical trial	62
MicroRNA interplay between hepatic stellate cell quiescence and activation	60
A review on possible mechanistic insights of Nitazoxanide for repurposing in COVID-19	59
Quercetin loaded chitosan tripolyphosphate nanoparticles accelerated cutaneous wound healing in Wistar rats	59
TRPM8 channels: A review of distribution and clinical role	58
The therapeutic efficacy of quercetin in combination with antiviral drugs in hospitalized COVID-19 patients: A randomized controlled trial	58
The footprint of kynurenine pathway in every cancer: a new target for chemotherapy	57
Pharmacodynamic effects and molecular mechanisms of lignans from Schisandra chinensis Turcz. (Baill.), a current review	56
Angiotensin-converting enzyme 2 (ACE2) receptor and SARS-CoV-2: Potential therapeutic targeting	55
NMDA and AMPA receptors dysregulation in Alzheimer's disease	55
Current herbal medicine as an alternative treatment in dentistry: In vitro, in vivo and clinical studies	54
AgRP/NPY and POMC neurons in the arcuate nucleus and their potential role in treatment of obesity	54
Endoplasmic reticulum as a potential therapeutic target for covid-19 infection management?	53
Statins and PCSK9 inhibitors: A new lipid-lowering therapy	52
Melatonin is a potential adjuvant to improve clinical outcomes in individuals with obesity and diabetes with coexistence of Covid-19	51
Dapagliflozin exerts anti-inflammatory effects via inhibition of LPS-induced TLR-4 overexpression and NF-κB activation in human endothelial cells and differentiated macrophages	51
Hesperetin ameliorates DSS-induced colitis by maintaining the epithelial barrier via blocking RIPK3/MLKL necroptosis signaling	51
Vascular disrupting agents in cancer therapy	50
Update on therapeutic approaches and emerging therapies for SARS-CoV-2 virus	50
The pharmacological activity of berberine, a review for liver protection	49
The natural (poly)phenols as modulators of microglia polarization via TLR4/NF-κB pathway exert anti-inflammatory activity in ischemic stroke	49
Integrative transcriptomics analysis of lung epithelial cells and identification of repurposable drug candidates for COVID-19	49
The role of CD44 in cancer chemoresistance: A concise review	49