OOIR: Observatory of International Research

Papers

(The H4-Index of European Journal of Pharmacology is 49. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)

Article	Citations
Alzheimer's disease: Recent treatment strategies	335
Treatment for COVID-19: An overview	227
siRNA: Mechanism of action, challenges, and therapeutic approaches	198
COVID-19 vaccine: A recent update in pipeline vaccines, their design and development strategies	190
Ferroptosis involves in renal tubular cell death in diabetic nephropathy	138
ACSL family: The regulatory mechanisms and therapeutic implications in cancer	136
Dexamethasone: Therapeutic potential, risks, and future projection during COVID-19 pandemic	126
Naringenin and naringin in cardiovascular disease prevention: A preclinical review	120
Flavonols as potential antiviral drugs targeting SARS-CoV-2 proteases (3CLpro and PLpro), spike protein, RNA-dependent RNA polymerase (RdRp) and angiotensin-converting enzyme II receptor (ACE2)	106
Geniposide alleviates diabetic nephropathy of mice through AMPK/SIRT1/NF-κB pathway	105
In silico pharmacokinetic and molecular docking studies of natural flavonoids and synthetic indole chalcones against essential proteins of SARS-CoV-2	96
Current advancements and future perspectives of immunotherapy in colorectal cancer research	94
Role of natural products for the treatment of Alzheimer's disease	89
A review of potential suggested drugs for coronavirus disease (COVID-19) treatment	89
Astragalus polysaccharide prevents ferroptosis in a murine model of experimental colitis and human Caco-2 cells via inhibiting NRF2/HO-1 pathway	88
COVID-19: A review of the proposed pharmacological treatments	86
Possibility of magnesium supplementation for supportive treatment in patients with COVID-19	85
Neuroprotective role of polyphenols against oxidative stress-mediated neurodegeneration	83
Remdesivir for treatment of COVID-19; an updated systematic review and meta-analysis	80
Curcumin, a traditional spice component, can hold the promise against COVID-19?	80
NMDA and AMPA receptors dysregulation in Alzheimer's disease	77
Angiopoietin inhibitors: A review on targeting tumor angiogenesis	75
The footprint of kynurenine pathway in every cancer: a new target for chemotherapy	75
TGF-β-induced fibrosis: A review on the underlying mechanism and potential therapeutic strategies	74
In silico molecular docking analysis for repurposing therapeutics against multiple proteins from SARS-CoV-2	73

AgRP/NPY and POMC neurons in the arcuate nucleus and their potential role in treatment of obesity	71
Dapagliflozin exerts anti-inflammatory effects via inhibition of LPS-induced TLR-4 overexpression and NF-κB activation in human endothelial cells and differentiated macrophages	70
No clinical benefit of high dose corticosteroid administration in patients with COVID-19: A preliminary report of a randomized clinical trial	68
Current herbal medicine as an alternative treatment in dentistry: In vitro, in vivo and clinical studies	67
The therapeutic efficacy of quercetin in combination with antiviral drugs in hospitalized COVID-19 patients: A randomized controlled trial	67
A review on possible mechanistic insights of Nitazoxanide for repurposing in COVID-19	65
Pharmacodynamic effects and molecular mechanisms of lignans from Schisandra chinensis Turcz. (Baill.), a current review	63
The natural (poly)phenols as modulators of microglia polarization via TLR4/NF-κB pathway exert anti-inflammatory activity in ischemic stroke	61
The pharmacological activity of berberine, a review for liver protection	59
Fisetin, potential flavonoid with multifarious targets for treating neurological disorders: An updated review	59
Vascular disrupting agents in cancer therapy	58
The Egr-1/miR-15a-5p/GPX4 axis regulates ferroptosis in acute myocardial infarction	58
Therapeutic potential of MCC950, a specific inhibitor of NLRP3 inflammasome	57
Angiogenesis as a potential treatment strategy for rheumatoid arthritis	56
The role of VEGF in cancer-induced angiogenesis and research progress of drugs targeting VEGF	56
MicroRNA-mediated autophagy regulation in cancer therapy: The role in chemoresistance/chemosensitivity	55
The role of CD44 in cancer chemoresistance: A concise review	55
Antiviral activity of chlorpromazine, fluphenazine, perphenazine, prochlorperazine, and thioridazine towards RNA-viruses. A review	55
Unraveling the mechanism of arbidol binding and inhibition of SARS-CoV-2: Insights from atomistic simulations	54
Modulation of the tumor microenvironment (TME) by melatonin	53
Integrative transcriptomics analysis of lung epithelial cells and identification of repurposable drug candidates for COVID-19	53
Capsaicin: TRPV1-independent mechanisms and novel therapeutic possibilities	52
The PI3K/Akt/mTOR signaling pathway in gastric cancer; from oncogenic variations to the possibilities for pharmacologic interventions	50
Ginsenoside Rg1 ameliorated experimental colitis by regulating the balance of M1/M2 macrophage polarization and the homeostasis of intestinal flora	50
Parkinson's disease in women: Mechanisms underlying sex differences	49
Ameliorating and protective effects mesalazine on ethanol-induced gastric ulcers in experimental rats	49