OOIR: Observatory of International Research

Papers

(The TQCC of European Journal of Immunology is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Impressum	141
Linking Epitope‐Specific T‐Cell Receptors to IFNγ Secretion Using Nanovial Technology	103
Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), 26–29 September, 2023, Strasbourg, France	77
Immunomodulation under the lens of real‐time in vivo imaging	73
Cover Story: Eur. J. Immunol. 4'23	73
Dimethyl itaconate selectively targets inflammatory and metabolic pathways in chronic lymphocytic leukemia	66
Fluorochrome‐labeled inhibitors of caspase‐1 require membrane permeabilization to efficiently access caspase‐1 in macrophages	65
Bead‐by‐bead normalization of single antigen assays: A necessary step for accurate detection of weak anti‐HLA antibodies	56
Epigenetic Regulation of CD8 ⁺ Effector T Cell Differentiation by PDCD5	55
TEAMwork: Interplay of Post‐Transcriptional Mechanisms, Epigenetics and Metabolism in (Auto‐)Immunity	52
In memoriam Martin Röllinghoff (1941–2022)	48
Airway epithelial type‐2 alarmin profiles: Blood eosinophil counts remain in memory	44
Surface CD69‐Negative CD4 and CD8 Bone Marrow‐Resident Human Memory T Cells	43
Immunoregulation of asthma by type 2 cytokine therapies: Treatments for all ages?	42
The Streptomyces Metabolite Thiostrepton Inhibits Regulatory T Cell Differentiation and Function to Boost Antitumor Immune Responses	41
Immune signature of patients with cardiovascular disease predicts increased risk for a severe course of COVID‐19	40
The potential of γδ CAR and TRuC T cells: An unearthed treasure	39
Guidelines for mouse and human DC functional assays	38
Intrahepatic plasma cells, but not atypical memory B cells, associate with clinical phases of chronic hepatitis B	38
Staphylococcus aureus ‐derived factors promote human Th9 cell polarization and enhance a transcriptional program associated with allergic inflammation	36
Fate‐mapping studies in inbred mice: A model for understanding macrophage development and homeostasis?	36
Regulatory T cells as a therapeutic approach for inflammatory bowel disease	35
Four challenges to CAR T cells breaking the glass ceiling	35
Emerging roles of host and microbial bioactive lipids in inflammatory bowel diseases	34
Neutrophil subsets in noncancer liver diseases: Cellular crosstalk and therapeutic targets	34

Sustained innate interferon is an essential inducer of tertiary lymphoid structures	34
Cover Story: Eur. J. Immunol. 6'26	33
Induction of Tolerogenic Dendritic Cells by a Noncoding Oligonucleotide	33
Mast cells in type 2 skin inflammation: Maintenance and function	32
Termination of CD40L co‐stimulation promotes human B cell differentiation into antibody‐secreting cells	32
The Phenotypical and Functional Effect of PGE2 on Human Macrophages	32
In this issue	31
	31
Issue Information: Eur. J. Immunol. 1'25	30
Communication and transparency at EJI: Supporting authors through their publishing experience	29
Issue Information: Eur. J. Immunol. 8'23	29
Cover Story: Eur. J. Immunol. 1'24	29
T‐cell signature cytokines distinguish pulmonary sarcoidosis from pulmonary tuberculosis	28
The Young Immunologists' Podcast: Immunology and Much More	28
Czech Young Immunologists: Bound by science, united in purpose	27
Potentiation of the axis involving pentose phosphate pathway/NADPH oxidase/reactive oxygen species drives higher IL‐10 production in monocytes of Sub‐Saharan Africans	27
Cytokine Autoantibodies Alter Gene Expression Profiles of Healthy Donors	27
Researcher Reflections—Inspiring Paths in Academia	26
Functional Fc receptors are crucial in antibody‐mediated protection against cytomegalovirus	26
Mastering Immunity: Antibody Feedback as a Driver of Germinal Center Fate and Vaccine Responses	25
Hyperinflammation by Human Macrophages Induced by SARS‐CoV‐2 Anti‐Spike IgG Is Dependent on Glucose and Fatty Acid Metabolism	24
Fully functional monocytic MDSC generation from the murine HoxB8 cell line	24
Charting Bird Tregs	24
	24
Transcriptome–Proteome Analysis of Human Naive and Memory B Cell Subsets Reveals Isotype and Subclass‐Specific Phenotypes	23
IL‐4, IL‐15, and Type I Interferon Orchestrate the Shaping of the Heterogeneity of Virtual Memory CD8 T Cells	23
Enhanced in vitro type 1 conventional dendritic cell generation via the recruitment of hematopoietic stem cells and early progenitors by Kit ligand	23
Immunomodulation of neutrophil granulocyte functions by bacterial polyphosphates	23
Key actors in neuropathophysiology: The role of γδ T cells	23
TLR9‐Driven S‐Palmitoylation in Dendritic Cells Reveals Immune and Metabolic Protein Targets	23
IQGAP1 Influences Neutrophil Maturation and Its Effector Functions	23
AK2‐Deficient Mice Recapitulate Impaired Lymphopoiesis of Reticular Dysgenesis Patients, but Also Lack Erythropoiesis	23
Mouse dendritic cells and other myeloid subtypes in healthy lymph nodes and skin: 26‐Color flow cytometry panel for immune phenotyping	22
Immediate major dynamic changes in the T‐ and NK‐cell subset composition after cardiac transplantation	22
Immunology meeting	21
YF17D‐based vaccines – standing on the shoulders of a giant	21
The VEGF‐Mediated Cytoprotective Ability of MIF‐Licensed Mesenchymal Stromal Cells in House Dust Mite‐Induced Epithelial Damage	21
Impressum	21
Engineering Soluble Recombinant BCMA for Ide‐Cel Labeling	21
EFIS News	21
Innate immunity champions: The diverse functions of macrophages	21
Impressum	21
Human Blood IgA ⁺ Memory B Cells Differ From IgG ⁺ B Cells by Expressing Gut‐Homing and Regulatory	20
Contents: Eur. J. Immunol. 11'22	20
B Cell Receptor Repertoire Analysis of the CD21 ^lo B Cell Compartment in Healthy Individuals, Patients With Sjögren's Disease, and Patients With Radi	20
In this issue	20
Acquired immune resistance is associated with interferon signature and modulation of KLF6/c‐MYB transcription factors in myeloid leukemia	20
Journal roundup	20
EXPRESSION OF CONCERN: Activation of Epstein‐Barr Virus/C3d Receptor (gp140, CR2, CD21) on Human Cell Surface Triggers pp60src and Akt‐GSK3 Activities Upstream and Downstream to PI 3‐Kinase, Respectiv	19
Distinct Tissue‐Dependent Composition and Gene Expression of Human Fetal Innate Lymphoid Cells	19

	19
Knockout of SLy1 decreases double‐negative thymocyte proliferation and protects mice from p53‐induced tumor formation	19
Tyrosine kinase inhibitor cabozantinib impacts dendritic and natural killer cells immune response in C38 syngeneic tumor model	19
	19
MicroRNA‐146a deficiency enhances host protection against murine cytomegalovirus	19
Microenvironmental signals shaping NK‐cell reactivity in cancer	18
PP2A catalytic subunit alpha is critically required for CD8 ⁺ T‐cell homeostasis and antibacterial responses	18
Novel homozygous CD46 variant with C‐isoform expression affects C3b inactivation in atypical hemolytic uremic syndrome	18
Single‐cell multi‐omics analysis of COVID‐19 patients with pre‐existing autoimmune diseases shows aberrant immune responses to infection	18
Nonreplicating synthetic mRNA vaccines: A journey through the European (Journal of Immunology) history	18
The Swiss Young Immunologists Society (SYIS): Empowering the next generation of immunologists	18
Dendritic cells generated from induced pluripotent stem cells and by direct reprogramming of somatic cells	18
Issue Information: Eur. J. Immunol. 12'25	18
Sex‐specific impact of psychosocial stress on hematopoiesis and blood leukocytes	18
Endogenous secretory leukocyte protease inhibitor inhibits microbial‐induced monocyte activation	18
Pamidronate‐Induced Clinical Remission in Chronic Non‐bacterial Osteomyelitis Is Associated with Reduced Vγ9Vδ2 T‐Cell Receptor Expression	18
The immunosuppressive drug cyclosporin A has an immunostimulatory function in CD8 ⁺ T cells	17
Release of IL‐1β and IL‐18 in human primary bronchial epithelial cells exposed to cigarette smoke is independent of NLRP3	17
Expanding our understanding of Guillain–Barré syndrome: Recent advances and clinical implications	17
Guidelines for mouse and human DC generation	17
Integrating Genetics and Environment to Find Causal Mechanisms for Multiple Sclerosis	17
DsbA‐L deletion attenuates LPS‐induced acute kidney injury by modulating macrophage polarization	17
The Memory Inflation Response Against Spread‐Defective CMV Requires Priming‐Independent CD4 ⁺ T Cell Help	16
Exploring How Cytoskeleton Dynamics Tunes T Cell Activation at the Immunological Synapse	16
Cover Story: Eur. J. Immunol. 12'23	16
Imaging Mass Cytometry‐Based Immune Profiling of Human Peyer's Patches in Patients with Crohn's Disease	16
	16
Mesenteric Adipose Tissue as a Modulator of Intestinal Inflammation: Mechanistic Insights and Model Systems in Crohn's Disease	16
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Interleukin‐2‐induced skin inflammation	16
Issue Information: Eur. J. Immunol. 7'23	16
Differential Runx3, Eomes, and T‐bet expression subdivides MS‐associated CD4 ⁺ T cells with brain‐homing capacity	16
Langerhans cells orchestrate apoptosis of DNA‐damaged keratinocytes upon high‐dose UVB skin exposure	16
Methiothepin downregulates SNAP‐23 and inhibits degranulation of rat basophilic leukemia cells and mouse bone marrow‐derived mast cells	16
Proteomics reveals a global phenotypic shift of NK cells in HCV patients treated with direct‐acting antivirals	16
Resolution of Autoimmune Uveitis Requires CCL20‐Dependent Regulatory T Cells	15
Lymphotoxins from distinct types of lymphoid cells differentially contribute to neuroinflammation	15
Human T Cell Responses to Flavivirus Vaccines	15
Prophylactic Inhaled Pattern Recognition Receptor Agonists Reprogram Lung Epithelial Response and Prevent Type 2 Allergic Inflammation	15
Georg Friedrich (Fritz) Melchers (27.4.1936–24.2.2025)	15
Booster Injection with Birch Pollen Extract Activates B‐Cellular Memory Responses in Patients Having Completed Allergen Immunotherapy	15
From simple to complex: Protein‐based biomarker discovery in tuberculosis	15
Bin‐based visualization of cytokine‐co‐expression patterns of IL‐10‐producing CD4 T cell subsets	15
Actinin‐4 controls survival signaling in B cells by limiting the lateral mobility of B‐cell antigen receptors	15
SIRPα: A key player in innate immunity	15
B‐Cell Differentiation of Human Hematopoietic Progenitors Is Efficiently Supported by Wharton Jelly‐Derived Mesenchymal Stem Cells	15
Acellular Pertussis Vaccines Induce CD8 ⁺ and CD4 ⁺ Regulatory T Cells That Suppress Protective Ti	14
Correction to “Tuning the Affinity of Chimeric Antigen Receptors Enhances the Function of Human Engineered Regulatory T Cells”	14
Puppet masters of B‐cell progenitor acute lymphoblastic leukemia: The preB cell receptor and the interleukin 7 receptor α	14
Therapeutic targeting of factor D and MASP3 in complement‐mediated diseases: Lessons learned from mouse studies	14
Portuguese Society of Immunology (SPI): Turning 50, inspired by the past, looking into the future	14
Impressum	14
Diversity of regulatory B cells: Markers and functions	14
A human immune system (HIS) mouse model that dissociates roles for mouse and human FcR⁺ cells during antibody‐mediated immune responses	14
Detection of dendritic cell subsets in the tumor microenvironment by multiplex immunohistochemistry	14
Molecular and functional in vivo characterisation of murine Dectin‐1 isoforms	13
A Novel PTPN2 Isoform Differentially Regulates Immune Response	13
PIEZO1‐mediated mechanosensing governs NK‐cell killing efficiency and infiltration in three‐dimensional matrices	13
	13
Antibiotic use during pregnancy is linked to offspring gut microbial dysbiosis, barrier disruption, and altered immunity along the gut–lung axis	13
TLR4 phosphorylation at tyrosine 672 activates the ERK/c‐FOS signaling module for LPS‐induced cytokine responses in macrophages	13
Inhibition of Melanoma Growth by Ex Vivo Expanded Tumor‐Specific CD8+ T Cells Is Dependent on the Configuration of Nanoscale Artificial APCs	13
Cover Story: Eur. J. Immunol. 5'26	13
Regulation of B‐cell function and expression of CD11c, T‐bet, and FcRL5 in response to different activation signals	13
TNF Production or TNFR2 Expression Characterize Distinct States of Regulatory T Cells that Cooperate in Treg Expansion in Cancer and Chronic Inflammation	12
Epigenetic Regulations in Autoimmunity and Cancer: from Basic Science to Translational Medicine	12
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Cover Story: Eur. J. Immunol. 8'23	12
	12
Generation of Regulatory T Cells Against Islet Neoantigen	12
Effect of Aspirin Challenge on Innate Lymphoid Cells in Asthma Patients With Aspirin Hypersensitivity	12
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Impressum	12
Cover Story: Eur. J. Immunol. 5'24	12
Characterization of human CD4 ⁺ EOMES ⁺ GzmK ⁺	12
CCR4 ⁺ CD8 ⁺ T cells clonally expand to differentiated effectors in murine psoriasis and in human	12
Contents: Eur. J. Immunol. 8'22	12
Issue Information: Eur. J. Immunol. 1'23	12
Impressum	12
Effects of altered salt intake and diet on cytokines in humans: A 20‐week randomized cross‐over intervention study	11

Microbial‐Immune Interplay in CNS Autoimmune Diseases: Lessons from Animal Models and Clinical Studies	11
Stable β2‐Microglobulin–HLA Class I Association Reshapes the Antigenic Landscape and TCR Recognition of Cancer‐Associated Epitopes	11
Vitamin A‐treated natural killer cells reduce interferon‐gamma production and support regulatory T‐cell differentiation	11
Neural Crest‐Derived Mesenchymal Cells Support Thymic Reconstitution After Lethal Irradiation	11
Baseline Single‐Cell Differences in Polyfunctionality Between Systemic Autoinflammatory Diseases Patients and Healthy Controls	11
High Extracellular K ⁺ Skews T‐Cell Differentiation Towards Tumour Promoting Th2 and T _reg Subsets	11
Interleukin 23 receptor: Expression and regulation in immune cells	11
High‐dimensional Spatial Immune Profiling Highlights Microglia‐Like Cells in Human Dorsal Root Ganglia	11
Bystander activation of tissue‐resident memory CD4 T cells: Getting by with a little help from unfamiliar T‐cell friends	11
Upregulation of IL4‐induced gene 1 enzyme by B2 cells during melanoma progression impairs their antitumor properties	11
Crafting an MSCA PhD Masterpiece: Guiding Students on the Verge of Discovery	11
Single‐Cell Profiling of Splenic Immune Ageing and Chronic Stress Adaptations in Mice With Natural Microbiota	11
Retinoic acid‐loaded liposomes induce human mucosal CD103 ⁺ dendritic cells that inhibit Th17 cells and drive regulatory T‐cell development in vitro	11
Chronic stimulation desensitizes β2‐adrenergic receptor responses in natural killer cells	11
Translational immunology: Applying fundamental discoveries to human health and autoimmune diseases	11
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IL1R2 Acts as a Negative Regulator of Monocyte Recruitment During Inflammation	11
Guidelines for DC preparation and flow cytometry analysis of mouse lymphohematopoietic tissues	11
The first year of young group of the Spanish Immunology Society: Progress, challenges, and next steps	11
Immunogenicity‐Guided Design of an Acinetobacter baumanii Vaccine	11
TLR2 on CD4+ and CD8+ T cells promotes control of Mycobacterium tuberculosis infection	11
Survival of Human Bone Marrow Plasma Cells In Vitro Depends on the Support of the Stromal Cells, PI3K, and Canonical NF‐kappaB Signaling	11
Foxp3⁺ regulatory T cells in the central nervous system and other nonlymphoid tissues	10
Cover Story: Eur. J. Immunol. 4'25	10
38‐Marker Full‐Spectrum Flow Cytometry Panel for the Comprehensive Profiling of γδ T Cells in Human Blood and Lymphoid Tissues	10
yEFIS 1^st Symposium: Shaping the future of Immunology in Europe, 10–11 November, 2022, Berlin, Germany	10
Multifaceted Role of ILCs in Metabolic Adaptations: From Adult to Neonate	10
yEFIS with EFIS Lead the Way to ECR Engagement at ECI2024	10
Interferon α and β induce differential transcriptional and functional metabolic phenotypes in human macrophages and blunt glycolysis in response to antigenic stimuli	10
Prmt5 deficient mouse B cells display RNA processing complexity and slower colorectal tumor progression	10
CD4 ⁺ T‐Cell‐Intrinsic IL‐6 Is Critical for Th17 Differentiation and Dampened Responsiveness to CD8 ⁺	10
Trametinib Suppresses the Stimulated T Cells Through G1 Arrest and Apoptosis	10
Regulation of DC metabolism by nitric oxide in murine GM‐CSF cultures	10
	10
Zfp362 potentiates murine colonic inflammation by constraining Treg cell function rather than promoting Th17 cell differentiation	10
ADAR1 Controls Macrophage Scavenging and Lipid‐Buffering Programs in Metabolic Tissues	10
Pro‐ and Anti‐Inflammatory Macrophages Adjust UCP2 Protein Levels Based on Their Intrinsic Metabolism and Available Metabolites	10
Combined Deletion of ZFP36L1 and ZFP36L2 Drives Superior Cytokine Production in T Cells at the Cost of Cell Fitness	10
Polymorphism in F pocket affects peptide selection and stability of type 1 diabetes‐associated HLA‐B39 allotypes	10
Characteristics and mechanisms of T‐cell senescence: A potential target for cancer immunotherapy	10
PD‐L2 Inhibits Protective Immunity, Th2 Cell Functional Quality, and GATA‐3 Expression During Filarial Nematode Infection	10
	10
Plasmodium berghei Radiation‐Attenuated Sporozoite‐Immunized Mice Require Infectious Sporozoite Challenge to Maintain Protective Immunity	10
Fine needle aspiration of human lymph nodes reveals cell populations and soluble interactors pivotal to immunological priming	10
A Unique Intraexonic Splicing Mechanism in the Immunoglobulin Domain of NKp30 Produces a Surface‐Expressed Receptor With Altered Ligand Specificity	10
CRISPR/Cas9‐Mediated Gene Knockout Reveals a Nonredundant Role for p16 ^INK4A in Controlling TCR‐Dependent and Independent CD8 T Cell Expansion	10
Deciphering the Human Germinal Center: A Review of Models to Study T–B Cell Interactions	9
Antibody density on bacteria regulates C1q recruitment by monoclonal IgG but not IgM	9
MicroRNAs targeting TGF‐β signaling exacerbate central nervous system autoimmunity by disrupting regulatory T cell development and function	9
Therapeutic tactics for targeting B lymphocytes in autoimmunity and cancer	9
	9
T helper cell subsets: diversification of the field	9
Altered TRPM3‐Dependent Cytosolic and Mitochondrial Calcium Influx in Natural Killer Cells of Post‐COVID‐19 Condition Patients	9
Cover Story: Eur. J. Immunol. 4'24	9
Meeting Report: German–Japanese Alliance in Immunology	9
Composition of fatty acids in a high‐fat diet affects adipose tissue inflammation by inducing calreticulin on adipocytes and activating group 1 innate lymphoid cells	9
FcµR and IgM‐Mediated Complement Activation Cooperate to Enhance Humoral Immunity	9
Cover Story: Eur. J. Immunol. 8'24	9
Issue Information: Eur. J. Immunol. 5'25	9
Influence of SLAM Family Receptors in the NK‐Cell‐Mediated Surveillance of Lymphoblastic Acute Leukemia	9
	9
Impact of the adenosine receptor A2BR expressed on myeloid cells on immune regulation during pregnancy	9
Rational design of polymer‐based particulate vaccine adjuvants	9
Sensing context: Inhibitory receptors on non‐hematopoietic cells	9
Ccl21a , Rather Than Ccl21b , is Essential for Thymocyte Migration in Mouse	9
Cover Story: Eur. J. Immunol. 11'23	9
SARS‐CoV‐2 variants of concern elicit divergent early immune responses in hACE2 transgenic mice	9
Impressum	9
Impressum	9
Synovial Tissue Macrophage Heterogeneity in Rheumatoid Arthritis	8
Immunity in malignant brain tumors: Tumor entities, role of immunotherapy, and specific contribution of myeloid cells to the brain tumor microenvironment	8
The complement system: A key player in the host response to infections	8
	8
Front cover story: Eur. J. Immunol. 11'22	8
Costimulatory capacity of CD137 mAbs on T cells depends on elaborate CRD structures but not on blocking ligand‒receptor binding	8
Autoantibodies targeting type I interferons: Prevalence, mechanisms of induction, and association with viral disease susceptibility	8
Decoding the Factor H‐Related Proteins: Gatekeepers of Complement Dysregulation in AMD	8
TOX Does Not Drive Sepsis‐Induced T‐Cell Exhaustion	8
GPR109A expressed on medullary thymic epithelial cells affects thymic Treg development	8
Methodological Insights Into T‐Cell Activation: CD3/CD28 Versus PMA/Ionomycin Stimulation	8
	8
Transcriptomic Signatures Predict Rubella Virus‐Induced Cytokine and Chemokine Responses in Female MMR Recipients	8
Issue Information: Eur. J. Immunol. 8'22	8
CD95L concatemers highlight different stoichiometries of CD95‐mediated apoptotic and nonapoptotic pathways	8
Antigen‐Specific Tolerance: Clinical and Preclinical Approaches in Autoimmunity	8
Identification and Mapping of Human Lymph Node Stromal Cell Subsets by Combining Single‐Cell RNA Sequencing with Spatial Transcriptomics	8
Sphingosine‐1‐phosphate receptor type 4 is critically involved in the regulation of peritoneal B‐1 cell trafficking and distribution in vivo	8
KIRA6 is an Effective and Versatile Mast Cell Inhibitor of IgE‐mediated Activation	8
Impressum	8
Cover Story: Eur. J. Immunol. 3'23	8
Issue Information: Eur. J. Immunol. 4'26	7
Cover Story: Eur. J. Immunol. 7'26	7
	7
Structure‐Guided Engineering of TIGIT to Modulate Its Interaction With Nectin‐4, a Tumour‐Specific Antigen for the Development of Therapeutic Strategy	7
A Mouse Model for Generation of Gut Lamina Propria Plasma Cells Specific for a Deamidated Gluten Peptide	7