OOIR: Observatory of International Research

Papers

(The TQCC of European Journal of Immunology is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)

Article	Citations
Journal roundup	317
Transglutaminase 2 affinity and enzyme‐substrate intermediate stability as determining factors for T‐cell responses to gluten peptides in celiac disease	115
	115
Airway epithelial type‐2 alarmin profiles: Blood eosinophil counts remain in memory	71
Fate‐mapping studies in inbred mice: A model for understanding macrophage development and homeostasis?	71
Dimethyl itaconate selectively targets inflammatory and metabolic pathways in chronic lymphocytic leukemia	71
Integrin activation enables rapid detection of functional Vδ1⁺ and Vδ2⁺ γδ T cells	68
Impressum	66
Issue Information: Eur. J. Immunol. 10'21	65
Immunomodulation under the lens of real‐time in vivo imaging	60
Sustained innate interferon is an essential inducer of tertiary lymphoid structures	54
In memoriam Martin Röllinghoff (1941–2022)	52
Cover Story: Eur. J. Immunol. 4'23	52
Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), 26–29 September, 2023, Strasbourg, France	48
Impressum	46
Inborn errors of immunity and immunodeficiencies: Antibody‐mediated pathology and autoimmunity as a consequence of impaired immune reactions	45
Intrahepatic plasma cells, but not atypical memory B cells, associate with clinical phases of chronic hepatitis B	44
Immune signature of patients with cardiovascular disease predicts increased risk for a severe course of COVID‐19	43
Bead‐by‐bead normalization of single antigen assays: A necessary step for accurate detection of weak anti‐HLA antibodies	42
Fluorochrome‐labeled inhibitors of caspase‐1 require membrane permeabilization to efficiently access caspase‐1 in macrophages	41
The potential of γδ CAR and TRuC T cells: An unearthed treasure	41
Staphylococcus aureus‐derived factors promote human Th9 cell polarization and enhance a transcriptional program associated with allergic inflammation	40
A pair of noncompeting neutralizing human monoclonal antibodies protecting from disease in a SARS‐CoV‐2 infection model	40
Guidelines for mouse and human DC functional assays	39
Termination of CD40L co‐stimulation promotes human B cell differentiation into antibody‐secreting cells	37

B‐cell modulation with anti‐CD79b antibodies ameliorates experimental autoimmune encephalitis in mice	37
Peptidylprolyl isomerase C (Ppic) regulates invariant Natural Killer T cell (iNKT) differentiation in mice	36
Metabolic dynamics instruct CD8⁺ T‐cell differentiation and functions	36
Immunoregulation of asthma by type 2 cytokine therapies: Treatments for all ages?	36
Emerging roles of host and microbial bioactive lipids in inflammatory bowel diseases	36
Neutrophil subsets in noncancer liver diseases: Cellular crosstalk and therapeutic targets	35
Epigenetic Regulation of CD8⁺ Effector T Cell Differentiation by PDCD5	33
Four challenges to CAR T cells breaking the glass ceiling	33
	31
Mast cells in type 2 skin inflammation: Maintenance and function	31
Regulatory T cells as a therapeutic approach for inflammatory bowel disease	31
Immediate major dynamic changes in the T‐ and NK‐cell subset composition after cardiac transplantation	30
Back cover story: Eur. J. Immunol. 6'21	29
Issue Information: Eur. J. Immunol. 1'25	28
In this issue	28
Cereblon regulates NK cell cytotoxicity and migration via Rac1 activation	28
Enhanced in vitro type 1 conventional dendritic cell generation via the recruitment of hematopoietic stem cells and early progenitors by Kit ligand	27
LCMV induced downregulation of HVEM on antiviral T cells is critical for an efficient effector response	27
Abortive HIV‐1 RNA induces pro‐IL‐1β maturation via protein kinase PKR and inflammasome activation in humans	26
T‐cell signature cytokines distinguish pulmonary sarcoidosis from pulmonary tuberculosis	26
Fully functional monocytic MDSC generation from the murine HoxB8 cell line	26
Issue Information: Eur. J. Immunol. 8'23	26
Metabolic reprograming shapes neutrophil functions in severe COVID‐19	26
YF17D‐based vaccines – standing on the shoulders of a giant	25
Global k_off‐rates of polyclonal T‐cell populations merge subclonal avidities and predict functionality	25
Paradoxical immunodeficiencies—When failures of innate immunity cause immunopathology	25
Cover Story: Eur. J. Immunol. 1'24	25
Potentiation of the axis involving pentose phosphate pathway/NADPH oxidase/reactive oxygen species drives higher IL‐10 production in monocytes of Sub‐Saharan Africans	25
Mouse dendritic cells and other myeloid subtypes in healthy lymph nodes and skin: 26‐Color flow cytometry panel for immune phenotyping	25
Cytokine Autoantibodies Alter Gene Expression Profiles of Healthy Donors	24
E‐Cadherin restricts mast cell degranulation in mice	24
Human myeloid‐derived suppressor cell expansion during sepsis is revealed by unsupervised clustering of flow cytometric data	24
	23
Functional Fc receptors are crucial in antibody‐mediated protection against cytomegalovirus	23
Immunomodulation of neutrophil granulocyte functions by bacterial polyphosphates	23
Communication and transparency at EJI: Supporting authors through their publishing experience	23
MHC class I molecules co‐stimulate NK1.1 signaling and enhance Ca²⁺ flux in murine NK cells	23
The Young Immunologists' Podcast: Immunology and Much More	22
Researcher Reflections—Inspiring Paths in Academia	22
Innate immunity champions: The diverse functions of macrophages	22
IQGAP1 Influences Neutrophil Maturation and Its Effector Functions	22
BOB.1/OBF.1 is required during B‐cell ontogeny for B‐cell differentiation and germinal center function	22
GPA33 is expressed on multiple human blood cell types and distinguishes CD4⁺ central memory T cells with and without effector function	21
Current research and unmet needs in allergy and immunology in Germany: report presented by the DGfI and DGAKI task force Allergy & Immunology	21
Czech Young Immunologists: Bound by science, united in purpose	21
	20
Key actors in neuropathophysiology: The role of γδ T cells	20
The VEGF‐Mediated Cytoprotective Ability of MIF‐Licensed Mesenchymal Stromal Cells in House Dust Mite‐Induced Epithelial Damage	20
In this issue	19
Release of IL‐1β and IL‐18 in human primary bronchial epithelial cells exposed to cigarette smoke is independent of NLRP3	19

Altered increase in STAT1 expression and phosphorylation in severe COVID‐19	18
Back cover story: Eur. J. Immunol. 5'21	18
Single‐cell multi‐omics analysis of COVID‐19 patients with pre‐existing autoimmune diseases shows aberrant immune responses to infection	18
Microenvironmental signals shaping NK‐cell reactivity in cancer	18
DsbA‐L deletion attenuates LPS‐induced acute kidney injury by modulating macrophage polarization	18
Immunology meeting	18
Distinct Tissue‐Dependent Composition and Gene Expression of Human Fetal Innate Lymphoid Cells	17
MicroRNA‐146a deficiency enhances host protection against murine cytomegalovirus	17
Human cDC1s display constitutive activation of the UPR sensor IRE1	17
Nonreplicating synthetic mRNA vaccines: A journey through the European (Journal of Immunology) history	17
Langerhans cells orchestrate apoptosis of DNA‐damaged keratinocytes upon high‐dose UVB skin exposure	17
Intestinal homeostasis and inflammation: Gut microbiota at the crossroads of pancreas–intestinal barrier axis	16
Impressum	16
Pamidronate‐Induced Clinical Remission in Chronic Non‐bacterial Osteomyelitis Is Associated with Reduced Vγ9Vδ2 T‐Cell Receptor Expression	16
B Cell Receptor Repertoire Analysis of the CD21^lo B Cell Compartment in Healthy Individuals, Patients With Sjögren's Disease, and Patients With Radiographic Axial Spondyloarthritis	16
Acquired immune resistance is associated with interferon signature and modulation of KLF6/c‐MYB transcription factors in myeloid leukemia	16
The Swiss Young Immunologists Society (SYIS): Empowering the next generation of immunologists	16
Contents: Eur. J. Immunol. 11'22	16
Endogenous secretory leukocyte protease inhibitor inhibits microbial‐induced monocyte activation	16
Differential Runx3, Eomes, and T‐bet expression subdivides MS‐associated CD4⁺ T cells with brain‐homing capacity	16
Journal roundup	15
Knockout of SLy1 decreases double‐negative thymocyte proliferation and protects mice from p53‐induced tumor formation	15
Contents: Eur. J. Immunol. 12'21	15
In this issue	15
Dendritic cells generated from induced pluripotent stem cells and by direct reprogramming of somatic cells	15
Contents: Eur. J. Immunol. 7'22	15
Differential regulation of CD8⁺CD86⁺ Vγ1.1⁺ γδT cell responses in skin barrier tissue protection and homeostatic maintenance	15
Impressum	14
EFIS News	14
Tyrosine kinase inhibitor cabozantinib impacts dendritic and natural killer cells immune response in C38 syngeneic tumor model	14
	14
PP2A catalytic subunit alpha is critically required for CD8⁺ T‐cell homeostasis and antibacterial responses	14
The immunosuppressive drug cyclosporin A has an immunostimulatory function in CD8⁺ T cells	14
Sex‐specific impact of psychosocial stress on hematopoiesis and blood leukocytes	14
	14
Guidelines for mouse and human DC generation	13
	13
Issue Information: Eur. J. Immunol. 7'23	13
Novel homozygous CD46 variant with C‐isoform expression affects C3b inactivation in atypical hemolytic uremic syndrome	13
Helios is a marker, not a driver, of human Treg stability	13
Bin‐based visualization of cytokine‐co‐expression patterns of IL‐10‐producing CD4 T cell subsets	13
Expanding our understanding of Guillain–Barré syndrome: Recent advances and clinical implications	13
Hyperlipidemia‐induced metabolic changes in regulatory T cells result in altered function	13
SARS‐CoV‐2‐specific T cells are generated in less than half of allogeneic HSCT recipients failing to seroconvert after COVID‐19 vaccination	13
Methiothepin downregulates SNAP‐23 and inhibits degranulation of rat basophilic leukemia cells and mouse bone marrow‐derived mast cells	12
Proteomics reveals a global phenotypic shift of NK cells in HCV patients treated with direct‐acting antivirals	12
SIRPα: A key player in innate immunity	12
Therapeutic targeting of factor D and MASP3 in complement‐mediated diseases: Lessons learned from mouse studies	12
ACKR1 favors transcellular over paracellular T‐cell diapedesis across the blood‐brain barrier in neuroinflammation in vitro	12
Lymphotoxins from distinct types of lymphoid cells differentially contribute to neuroinflammation	12
Cover story: Eur. J. Immunol. 7'22	12
	12
Actinin‐4 controls survival signaling in B cells by limiting the lateral mobility of B‐cell antigen receptors	12
From simple to complex: Protein‐based biomarker discovery in tuberculosis	12
Mutant B2M‐HLA‐E and B2M‐HLA‐G fusion proteins protects universal chimeric antigen receptor‐modified T cells from allogeneic NK cell‐mediated lysis	12
Cover Story: Eur. J. Immunol. 12'23	12
A human immune system (HIS) mouse model that dissociates roles for mouse and human FcR⁺ cells during antibody‐mediated immune responses	12
Augmented neutralization of SARS‐CoV‐2 Omicron variant by boost vaccination and monoclonal antibodies	12
Correction	12
Diversity of regulatory B cells: Markers and functions	12
Interleukin‐2‐induced skin inflammation	12
PDGFRα‐lineage origin directs monocytes to trafficking proficiency to support peripheral immunity	11
Puppet masters of B‐cell progenitor acute lymphoblastic leukemia: The preB cell receptor and the interleukin 7 receptor α	11
Anca Catrina 1971–2021	11
CCR4⁺CD8⁺ T cells clonally expand to differentiated effectors in murine psoriasis and in human psoriatic arthritis	11
PIEZO1‐mediated mechanosensing governs NK‐cell killing efficiency and infiltration in three‐dimensional matrices	11
Antibiotic use during pregnancy is linked to offspring gut microbial dysbiosis, barrier disruption, and altered immunity along the gut–lung axis	11
Impressum	11
Back cover story: Eur. J. Immunol. 7'21	11
In this issue	11
Bruton's tyrosine kinase inhibition induces rewiring of proximal and distal B‐cell receptor signaling in mice	11
Characterization of human CD4⁺EOMES⁺GzmK⁺ T‐cell subsets unveils an uncoupling of suppressive functions from IL‐10‐producing capacities	11
Portuguese Society of Immunology (SPI): Turning 50, inspired by the past, looking into the future	11
Contents: Eur. J. Immunol. 7'21	11
Molecular and functional in vivo characterisation of murine Dectin‐1 isoforms	11
TLR4 phosphorylation at tyrosine 672 activates the ERK/c‐FOS signaling module for LPS‐induced cytokine responses in macrophages	10
Detection of dendritic cell subsets in the tumor microenvironment by multiplex immunohistochemistry	10
Non‐zero‐sum microbiome immune system interactions	10
Contents: Eur. J. Immunol. 8'22	10
TLR2 on CD4+ and CD8+ T cells promotes control of Mycobacterium tuberculosis infection	10

	10
Front cover story: Eur. J. Immunol. 2'22	10
Deletion of TLR2⁺ erythro‐myeloid progenitors leads to embryonic lethality in mice	10
Regulation of B‐cell function and expression of CD11c, T‐bet, and FcRL5 in response to different activation signals	10
Epigenetic Regulations in Autoimmunity and Cancer: from Basic Science to Translational Medicine	10
Characterization of SARS‐CoV‐2 and common cold coronavirus‐specific T‐cell responses in MIS‐C and Kawasaki disease children	10
Survival of Human Bone Marrow Plasma Cells In Vitro Depends on the Support of the Stromal Cells, PI3K, and Canonical NF‐kappaB Signaling	10
Bystander activation of tissue‐resident memory CD4 T cells: Getting by with a little help from unfamiliar T‐cell friends	10
Compartmentalized multicellular crosstalk in lymph nodes coordinates the generation of potent cellular and humoral immune responses	10
IL1R2 Acts as a Negative Regulator of Monocyte Recruitment During Inflammation	10
Specificity of mouse and human Fcgamma receptors and their polymorphic variants for IgG subclasses of different species	10
Impressum	10
Upregulation of IL4‐induced gene 1 enzyme by B2 cells during melanoma progression impairs their antitumor properties	10
Crafting an MSCA PhD Masterpiece: Guiding Students on the Verge of Discovery	10
Cover Story: Eur. J. Immunol. 5'24	10
Impressum	10
Cover Story: Eur. J. Immunol. 8'23	10
High Extracellular K⁺ Skews T‐Cell Differentiation Towards Tumour Promoting Th2 and T_reg Subsets	9
Effects of altered salt intake and diet on cytokines in humans: A 20‐week randomized cross‐over intervention study	9
	9
Vitamin A‐treated natural killer cells reduce interferon‐gamma production and support regulatory T‐cell differentiation	9
Interleukin 23 receptor: Expression and regulation in immune cells	9
Guidelines for DC preparation and flow cytometry analysis of mouse lymphohematopoietic tissues	9
Impressum	9
	9
Neuroimmune interactions in peripheral tissues	9
Neural Crest‐Derived Mesenchymal Cells Support Thymic Reconstitution After Lethal Irradiation	9
Chronic stimulation desensitizes β2‐adrenergic receptor responses in natural killer cells	9
Issue Information: Eur. J. Immunol. 1'23	9
Translational immunology: Applying fundamental discoveries to human health and autoimmune diseases	9
Retinoic acid‐loaded liposomes induce human mucosal CD103⁺ dendritic cells that inhibit Th17 cells and drive regulatory T‐cell development in vitro	9
Autoimmunity and SARS‐CoV‐2 infection: Unraveling the link in neurological disorders	9
The first year of young group of the Spanish Immunology Society: Progress, challenges, and next steps	9
Regulatory T cells and transplantation tolerance: Emerging from the darkness?	8
Trametinib Suppresses the Stimulated T Cells Through G1 Arrest and Apoptosis	8
Foxp3⁺ regulatory T cells in the central nervous system and other nonlymphoid tissues	8
Zfp362 potentiates murine colonic inflammation by constraining Treg cell function rather than promoting Th17 cell differentiation	8
6^th European Congress of Immunology, 1–4 September 2021, Virtual meeting	8
Impressum	8
	8
Prmt5 deficient mouse B cells display RNA processing complexity and slower colorectal tumor progression	8
Combined Deletion of ZFP36L1 and ZFP36L2 Drives Superior Cytokine Production in T Cells at the Cost of Cell Fitness	8
T helper cell subsets: diversification of the field	8
Follicular helper T cell signature of replicative exhaustion, apoptosis, and senescence in common variable immunodeficiency	8
Fine needle aspiration of human lymph nodes reveals cell populations and soluble interactors pivotal to immunological priming	8
Regulation of DC metabolism by nitric oxide in murine GM‐CSF cultures	8
	8
Interferon α and β induce differential transcriptional and functional metabolic phenotypes in human macrophages and blunt glycolysis in response to antigenic stimuli	8
yEFIS 1^st Symposium: Shaping the future of Immunology in Europe, 10–11 November, 2022, Berlin, Germany	8
Plasmodium berghei Radiation‐Attenuated Sporozoite‐Immunized Mice Require Infectious Sporozoite Challenge to Maintain Protective Immunity	8
yEFIS with EFIS Lead the Way to ECR Engagement at ECI2024	8
Polymorphism in F pocket affects peptide selection and stability of type 1 diabetes‐associated HLA‐B39 allotypes	8
Cover Story: Eur. J. Immunol. 4'25	8
Characteristics and mechanisms of T‐cell senescence: A potential target for cancer immunotherapy	8
ICAP‐1 loss impairs CD8⁺ thymocyte development and leads to reduced marginal zone B cells in mice	8
	8
In this issue	8
Dendritic cells Trigger IFN‐γ secretion by NK cells independent of IL‐12 and IL‐18	8
Ex vivo microRNA and gene expression profiling of human Tr1‐like cells suggests a role for miR‐92a and ‐125a in the regulation of EOMES and IL‐10R	7
STAT6‐induced production of mucus and resistin‐like molecules in lung Club cells does not protect against helminth or influenza A virus infection	7
Autoantibodies targeting type I interferons: Prevalence, mechanisms of induction, and association with viral disease susceptibility	7
Issue Information: Eur. J. Immunol. 6'23	7
Therapeutic tactics for targeting B lymphocytes in autoimmunity and cancer	7
TOX Does Not Drive Sepsis‐Induced T‐Cell Exhaustion	7
Altered IgG glycosylation at COVID‐19 diagnosis predicts disease severity	7
MicroRNAs targeting TGF‐β signaling exacerbate central nervous system autoimmunity by disrupting regulatory T cell development and function	7
Impressum	7
Cover Story: Eur. J. Immunol. 4'24	7
	7
CD95L concatemers highlight different stoichiometries of CD95‐mediated apoptotic and nonapoptotic pathways	7
Deciphering the Human Germinal Center: A Review of Models to Study T–B Cell Interactions	7
Impact of the adenosine receptor A2BR expressed on myeloid cells on immune regulation during pregnancy	7
Immunity in malignant brain tumors: Tumor entities, role of immunotherapy, and specific contribution of myeloid cells to the brain tumor microenvironment	7
PAD2 immunization induces ACPA in wild‐type and HLA‐DR4 humanized mice	7
Cover Story: Eur. J. Immunol. 8'24	7
	7
Verteporfin protects against Th17 cell‐mediated EAE independently of YAP inhibition	7
Composition of fatty acids in a high‐fat diet affects adipose tissue inflammation by inducing calreticulin on adipocytes and activating group 1 innate lymphoid cells	7
Sensing context: Inhibitory receptors on non‐hematopoietic cells	7
Dynamics of IL‐15/IL‐15R‐α expression in response to HSV‐1 infection reveal a novel mode of viral immune evasion counteracted by iNKT cells	7
Natural killer cell engagers in cancer immunotherapy: Next generation of immuno‐oncology treatments	7
Sphingosine‐1‐phosphate receptor type 4 is critically involved in the regulation of peritoneal B‐1 cell trafficking and distribution in vivo	7
Rational design of polymer‐based particulate vaccine adjuvants	7
The complement system: A key player in the host response to infections	7
Impressum	7
Antibody density on bacteria regulates C1q recruitment by monoclonal IgG but not IgM	7
SARS‐CoV‐2 variants of concern elicit divergent early immune responses in hACE2 transgenic mice	7
Cover Story: Eur. J. Immunol. 11'23	7
GPR109A expressed on medullary thymic epithelial cells affects thymic Treg development	7
Collagen type VI is the antigen recognized by the ER‐TR7 antibody	6
Cryptococcus gattii polysaccharide capsule: An insight on fungal‐host interactions and vaccine studies	6
c‐Rel employs multiple mechanisms to promote the thymic development and peripheral function of regulatory T cells in mice	6
PTEN is required for human Treg suppression of costimulation in vitro	6
KIRA6 is an Effective and Versatile Mast Cell Inhibitor of IgE‐mediated Activation	6
Differential Interleukin‐8 thresholds for chemotaxis and netosis in human neutrophils	6