European Journal of Immunology

Papers
(The TQCC of European Journal of Immunology is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)
ArticleCitations
Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)198
Seroprevalence of anti‐SARS‐CoV‐2 antibodies in COVID‐19 patients and healthy volunteers up to 6 months post disease onset172
Divergent SARS‐CoV‐2‐specific T‐ and B‐cell responses in severe but not mild COVID‐19 patients98
Expansion of plasmablasts and loss of memory B cells in peripheral blood from COVID‐19 patients with pneumonia92
Natural killer cell engagers in cancer immunotherapy: Next generation of immuno‐oncology treatments87
Human NK cells, their receptors and function74
Combined anti‐PD‐1 and anti‐CTLA‐4 checkpoint blockade: Treatment of melanoma and immune mechanisms of action71
Regulatory T cell targeting in cancer: Emerging strategies in immunotherapy68
Persistence of neutralizing antibodies a year after SARS‐CoV‐2 infection in humans67
Prevention and treatment of COVID‐19 disease by controlled modulation of innate immunity56
MDSC subtypes and CD39 expression on CD8+ T cells predict the efficacy of anti‐PD‐1 immunotherapy in patients with advanced NSCLC55
Viral infections in humans and mice with genetic deficiencies of the type I IFN response pathway54
Attenuated immune control of Epstein–Barr virus in humanized mice is associated with the multiple sclerosis risk factor HLA‐DR1551
Highly multiplexed tissue imaging using repeated oligonucleotide exchange reaction50
Cell‐mediated and humoral adaptive immune responses to SARS‐CoV‐2 are lower in asymptomatic than symptomatic COVID‐19 patients50
The expanding world of tissue‐resident macrophages49
JAK inhibitors: Ten years after49
High seroprevalence but short‐lived immune response to SARS‐CoV‐2 infection in Paris48
TNF‐α and IL‐1β sensitize human MSC for IFN‐γ signaling and enhance neutrophil recruitment46
CD8+ Tregs revisited: A heterogeneous population with different phenotypes and properties45
Treg cell therapy: How cell heterogeneity can make the difference44
Complement cascade in severe forms of COVID‐19: Recent advances in therapy43
CAR T cells: Building on the CD19 paradigm42
Peptide microarray‐based analysis of antibody responses to SARS‐CoV‐2 identifies unique epitopes with potential for diagnostic test development41
Helios is a marker, not a driver, of human Treg stability39
Transcriptional and posttranslational regulation of Th17/Treg balance in health and disease38
Ex vivo blockade of PI3K gamma or delta signaling enhances the antitumor potency of adoptively transferred CD8+ T cells38
Immune response in children with COVID‐19 is characterized by lower levels of T‐cell activation than infected adults38
Tc17 biology and function: Novel concepts37
Natural killer cell‐mediated ADCC in SARS‐CoV‐2‐infected individuals and vaccine recipients37
Metabolic reprograming shapes neutrophil functions in severe COVID‐1934
Comprehensive characterization of myeloid cells during wound healing in healthy and healing‐impaired diabetic mice33
Crossing the barriers: Revisiting the gut feeling in rheumatoid arthritis32
The role of the gut microbiota and microbial metabolites in neuroinflammation32
Differential Interleukin‐8 thresholds for chemotaxis and netosis in human neutrophils32
Anti‐heart antibodies levels and their correlation with clinical symptoms and outcomes in patients with confirmed or suspected diagnosis COVID‐1931
Loss of core fucosylation enhances the anticancer activity of cytotoxic T lymphocytes by increasing PD‐1 degradation31
The thioredoxin‐1 inhibitor Txnip restrains effector T‐cell and germinal center B‐cell expansion31
Mechanism of action of PD‐1 receptor/ligand targeted cancer immunotherapy31
LIPS method for the detection of SARS‐CoV‐2 antibodies to spike and nucleocapsid proteins30
Manipulation of epithelial integrity and mucosal immunity by host and microbiota‐derived metabolites30
IL‐17A expressed on neutrophil extracellular traps promotes mesenchymal stem cell differentiation toward bone‐forming cells in ankylosing spondylitis30
Icaritin inhibits PD‐L1 expression by Targeting Protein IκB Kinase α30
Tumor‐derived microparticles in tumor immunology and immunotherapy30
Antigen‐dependent multistep differentiation of T follicular helper cells and its role in SARS‐CoV‐2 infection and vaccination30
Altered increase in STAT1 expression and phosphorylation in severe COVID‐1930
A single subcutaneous or intranasal immunization with adenovirus‐based SARS‐CoV‐2 vaccine induces robust humoral and cellular immune responses in mice30
Regulatory T‐cell development in the tumor microenvironment29
Anti‐IFN‐α/‐ω neutralizing antibodies from COVID‐19 patients correlate with downregulation of IFN response and laboratory biomarkers of disease severity29
Palmitate‐TLR4 signaling regulates the histone demethylase, JMJD3, in macrophages and impairs diabetic wound healing28
Granzyme A and CD160 expression delineates ILC1 with graded functions in the mouse liver28
Janus kinase signaling as risk factor and therapeutic target for severe SARS‐CoV‐2 infection28
Molecular mechanisms of nonself nucleic acid recognition by the innate immune system27
Regulatory T cell metabolism at the intersection between autoimmune diseases and cancer27
Neutrophil activation and neutrophil extracellular traps (NETs) in COVID‐19 ARDS and immunothrombosis26
CCR4 in cutaneous T‐cell lymphoma: Therapeutic targeting of a pathogenic driver26
Dysregulation in B‐cell responses and T follicular helper cell function in ADA2 deficiency patients26
Altered IgG glycosylation at COVID‐19 diagnosis predicts disease severity26
Systematic analysis of CD39, CD103, CD137, and PD‐1 as biomarkers for naturally occurring tumor antigen‐specific TILs25
Neutralizing antibodies to SARS‐CoV‐2 Omicron variant after third mRNA vaccination in health care workers and elderly subjects24
Protection against allergies: Microbes, immunity, and the farming effect24
Antigen‐driven PD‐1+TOX+BHLHE40+ and PD‐1+TOX+EOMES+ T lymphocytes regulate juvenile idiopathic arthritis 24
Fibroblast‐derived IL‐33 is dispensable for lymph node homeostasis but critical for CD8 T‐cell responses to acute and chronic viral infection24
COVID‐19 vaccines: Knowing the unknown24
Neuroimmune interactions in peripheral tissues23
Collagen type VI is the antigen recognized by the ER‐TR7 antibody23
Differential sensitivity of inflammatory macrophages and alternatively activated macrophages to ferroptosis23
‘Nur'turing tumor T cell tolerance and exhaustion: novel function for Nuclear Receptor Nur77 in immunity23
Human splenic polymorphonuclear myeloid‐derived suppressor cells (PMN‐MDSC) are strategically located immune regulatory cells in cancer23
Deregulated cellular circuits driving immunoglobulins and complement consumption associate with the severity of COVID‐19 patients22
TIM‐3 and CEACAM1 do not interact in cis and in trans22
RAG deficiencies: Recent advances in disease pathogenesis and novel therapeutic approaches22
Mechanisms of exTreg induction22
Enrichment of CCR6+CD8+ T cells and CCL20 in the lungs of mechanically ventilated patients with COVID‐1922
Circulating memory CD8+ T cells are limited in forming CD103+ tissue‐resident memory T cells at mucosal sites after reinfection22
Upregulation of CCR4 in activated CD8+ T cells indicates enhanced lung homing in patients with severe acute SARS‐CoV‐2 infection22
Identification of human cytotoxic ILC3s22
Sestrin1 inhibits oxidized low‐density lipoprotein‐induced activation of NLRP3 inflammasome in macrophages in a murine atherosclerosis model22
Regulation of the humoral type 2 immune response against allergens and helminths22
The association of Epstein‐Barr virus infection with CXCR3+ B‐cell development in multiple sclerosis: impact of immunotherapies22
IL‐33/ST2 as a potential target for tumor immunotherapy21
CTRP4 acts as an anti‐inflammatory factor in macrophages and protects against endotoxic shock21
Reduced concentrations of the B cell cytokine interleukin 38 are associated with cardiovascular disease risk in overweight subjects21
Innate immune inflammatory cell death: PANoptosis and PANoptosomes in host defense and disease21
Soluble pattern recognition molecules: Guardians and regulators of homeostasis at airway mucosal surfaces21
Measuring single‐cell protein secretion in immunology: Technologies, advances, and applications21
The role of cGAS/STING in intestinal immunity21
An integrative genomics approach identifies KDM4 as a modulator of trained immunity21
Expanded clinical‐grade membrane‐bound IL‐21/4‐1BBL NK cell products exhibit activity against acute myeloid leukemia in vivo21
Innate lymphoid cells and cancer: Role in tumor progression and inhibition20
Deep phenotypical characterization of human CD3+CD56+ T cells by mass cytometry20
Autophagy regulates long‐term cross‐presentation by murine dendritic cells20
Detailed and atypical HLA‐E peptide binding motifs revealed by a novel peptide exchange binding assay20
Malaria exposure drives both cognate and bystander human B cells to adopt an atypical phenotype19
T cells at work: How post‐transcriptional mechanisms control T cell homeostasis and activation19
Maintenance of quiescent immune memory in the bone marrow19
Human dendritic cell subsets: An updated view of their ontogeny and functional specialization18
Inhibition of tumor‐associated macrophages by trabectedin improves the antitumor adaptive immunity in response to anti‐PD‐1 therapy18
TLR7 endogenous ligands remodel glycolytic macrophages and trigger skin‐to‐joint crosstalk in psoriatic arthritis18
Maturation signatures of conventional dendritic cell subtypes in COVID‐19 suggest direct viral sensing18
High neutralizing potency of swine glyco‐humanized polyclonal antibodies against SARS‐CoV‐218
CD5 levels define functionally heterogeneous populations of naïve human CD4+ T cells18
Mutations of the gene FNIP1 associated with a syndromic autosomal recessive immunodeficiency with cardiomyopathy and pre‐excitation syndrome17
Intestinal microbiota disruption limits the isoniazid mediated clearance of Mycobacterium tuberculosis in mice17
Fetal‐derived macrophages persist and sequentially maturate in ovaries after birth in mice17
De novo polyamine synthesis supports metabolic and functional responses in activated murine NK cells17
Divergent chemokine receptor expression and the consequence for human IgG4 B cell responses17
Tumor‐associated human dendritic cell subsets: Phenotype, functional orientation, and clinical relevance16
Tofacitinib therapy intercepts macrophage metabolic reprogramming instigated by SARS‐CoV‐2 Spike protein16
Innate immune evasion by picornaviruses16
Cross talk between human regulatory T cells and antigen‐presenting cells: Lessons for clinical applications16
Withdrawn16
Interleukin‐17 producing mucosal associated invariant T cells ‐ emerging players in chronic inflammatory diseases?16
Towards gene therapy for IPEX syndrome16
Mesenchymal stromal cells‐derived small extracellular vesicles modulate DC function to suppress Th2 responses via IL‐10 in patients with allergic rhinitis16
SARS‐CoV2 pneumonia recovery is linked to expansion of innate lymphoid cells type 2 expressing CCR1016
White matter lesions in multiple sclerosis are enriched for CD20dim CD8+ tissue‐resident memory T cells16
PD‐1‐specific “Blocking” antibodies that deplete PD‐1+ T cells present an inconvenient variable in preclinical immunotherapy experiments16
A pair of noncompeting neutralizing human monoclonal antibodies protecting from disease in a SARS‐CoV‐2 infection model16
Transcriptional meta‐analysis of regulatory B cells15
AIDS patient with severe T cell depletion achieved control but not clearance of SARS‐CoV‐2 infection15
The presence of serum anti‐SARS‐CoV‐2 IgA appears to protect primary health care workers from COVID‐1915
Mutant B2M‐HLA‐E and B2M‐HLA‐G fusion proteins protects universal chimeric antigen receptor‐modified T cells from allogeneic NK cell‐mediated lysis15
Heterogeneity of germinal center B cells: New insights from single‐cell studies15
HLA‐DRB1*15:01 is a co‐receptor for Epstein–Barr virus, linking genetic and environmental risk factors for multiple sclerosis15
Inhibition of stearoyl‐CoA desaturases suppresses follicular help T‐ and germinal center B‐ cell responses15
Recognition of S100 proteins by Signal Inhibitory Receptor on Leukocytes‐1 negatively regulates human neutrophils15
ACKR1 favors transcellular over paracellular T‐cell diapedesis across the blood‐brain barrier in neuroinflammation in vitro15
4‐1BB costimulation promotes bystander activation of human CD8 T cells15
Metabolic dynamics instruct CD8+ T‐cell differentiation and functions15
Geranylgeranyl pyrophosphate amplifies Treg differentiation via increased IL‐2 expression to ameliorate DSS‐induced colitis15
Specificity of mouse and human Fcgamma receptors and their polymorphic variants for IgG subclasses of different species15
Impact of IgA isoforms on their ability to activate dendritic cells and to prime T cells14
Evolved to protect, designed to destroy: IL‐17‐producing γδ T cells in infection, inflammation, and cancer14
Pharmacological inhibition of RORC2 enhances human Th17‐Treg stability and function14
T‐cell memory in tissues14
Tryptophan and the innate intestinal immunity: Crosstalk between metabolites, host innate immune cells, and microbiota14
A novel method to identify Post‐Aire stages of medullary thymic epithelial cell differentiation14
Insights into coronavirus immunity taught by the murine coronavirus14
Characterization of SARS‐CoV‐2 and common cold coronavirus‐specific T‐cell responses in MIS‐C and Kawasaki disease children14
Sex differences regulate immune responses in experimental autoimmune encephalomyelitis and multiple sclerosis14
Chimeric antigen receptor‐modified human regulatory T cells that constitutively express IL‐10 maintain their phenotype and are potently suppressive14
GSDMD‐mediated NETosis promotes the development of acute respiratory distress syndrome13
Convalescent plasma treatment for COVID‐19: Tempering expectations with the influenza experience13
Molecular characterization of HLA class II binding to the LAG‐3 T cell co‐inhibitory receptor13
Tumor infiltrated immune cell types support distinct immune checkpoint inhibitor outcomes in patients with advanced non‐small cell lung cancer13
Human liver‐derived MAIT cells differ from blood MAIT cells in their metabolism and response to TCR‐independent activation13
Mycobacterium tuberculosis PPE18 protein inhibits MHC class II antigen presentation and B cell response in mice13
Prostaglandin regulation of type 2 inflammation: From basic biology to therapeutic interventions13
Human pregnancy levels of estrogen and progesterone contribute to humoral immunity by activating TFH/B cell axis13
Towards prevention of autoimmune diseases: The example of rheumatoid arthritis13
IgE in the pathophysiology and therapy of food allergy12
Driving T cells to human atherosclerotic plaques: CCL3/CCR5 and CX3CL1/CX3CR1 migration axes12
miR‐148a controls metabolic programming and survival of mature CD19‐negative plasma cells in mice12
Tissue‐resident mucosal‐associated invariant T (MAIT) cells in the human kidney represent a functionally distinct subset12
Broadly reactive human CD4+ T cells against Enterobacteriaceae are found in the naïve repertoire and are clonally expanded in the memory repertoire12
Abortive HIV‐1 RNA induces pro‐IL‐1β maturation via protein kinase PKR and inflammasome activation in humans12
Loss of microRNA‐147 function alleviates synovial inflammation through ZNF148 in rheumatoid and experimental arthritis12
Sphingosine 1‐phosphate/microRNA‐1249‐5p/MCP‐1 axis is involved in macrophage‐associated inflammation in fatty liver injury in mice12
Targeting B cells and plasma cells in autoimmune diseases: From established treatments to novel therapeutic approaches12
Longitudinal SARS‐CoV‐2 seroprevalence in Portugal and antibody maintenance 12 months after infection12
Innate immune signaling and immunothrombosis: New insights and therapeutic opportunities12
ChAdOx1‐S adenoviral vector vaccine applied intranasally elicits superior mucosal immunity compared to the intramuscular route of vaccination12
CCL25 and CCR9 is a unique pathway that potentiates pannus formation by remodeling RA macrophages into mature osteoclasts11
Differential effects of estradiol and progesterone on human T cell activation in vitro11
Immunological analysis of the murine anti‐CD3‐induced cytokine release syndrome model and therapeutic efficacy of anti‐cytokine antibodies11
Autoimmunity and SARS‐CoV‐2 infection: Unraveling the link in neurological disorders11
One year of Young EFIS: achievements and future directions11
Flow cytometry data mining by cytoChain identifies determinants of exhaustion and stemness in TCR‐engineered T cells11
Advanced glycation end products reduce macrophage‐mediated killing of Staphylococcus aureus by ARL8 upregulation and inhibition of autolysosome formation11
Evidence for an involvement of the ubiquitin‐like modifier ISG15 in MHC class I antigen presentation11
Intestinal homeostasis and inflammation: Gut microbiota at the crossroads of pancreas–intestinal barrier axis11
Human CXCR5+PD‐1+ CD8 T cells in healthy individuals and patients with hematologic malignancies11
Young immunologists of Europe, unite!11
The thioredoxin system: Balancing redox responses in immune cells and tumors11
Cell surface IL‐1α trafficking is specifically inhibited by interferon‐γ, and associates with the membrane via IL‐1R2 and GPI anchors11
Trigger‐dependent differences determine therapeutic outcome in murine primary hemophagocytic lymphohistiocytosis11
Immunotherapy of CT26 murine tumors is characterized by an oligoclonal response of tissue‐resident memory T cells against the AH1 rejection antigen11
Human type 1 and type 2 conventional dendritic cells express indoleamine 2,3‐dioxygenase 1 with functional effects on T cell priming11
Transcriptomic profiling of bovine blood dendritic cells and monocytes following TLR stimulation11
Treatment and management of primary antibody deficiency: German interdisciplinary evidence‐based consensus guideline11
Peritoneal dialysate‐range hypertonic glucose promotes T‐cell IL‐17 production that induces mesothelial inflammation10
CD73 contributes to anti‐inflammatory properties of afferent lymphatic endothelial cells in humans and mice10
Splenic erythroid progenitors decrease TNF‐α production by macrophages and reduce systemic inflammation in a mouse model of T cell‐induced colitis10
Conventional type 1 dendritic cells induce TH1, TH1‐like follicular helper T cells and regulatory T cells after antigen boost via DEC205 receptor10
Human NK cells responses are enhanced by CD56 engagement10
Young EFIS ‐ joining forces to support Early Career Researchers in Immunology10
Regulatory T cells as a therapeutic approach for inflammatory bowel disease10
IL‐31 transgenic mice show reduced allergen‐induced lung inflammation10
MS4A4A Regulates Arginase 1 Induction during Macrophage Polarization and Lung Inflammation in Mice10
Increased B‐cell activity with consumption of activated monocytes in severe COVID‐19 patients10
Guidelines for mouse and human DC generation10
Blood microparticles are a component of immune modulation in red blood cell transfusion10
Functional and metabolic dichotomy of murine γδ T cell subsets in cancer immunity10
Four challenges to CAR T cells breaking the glass ceiling10
Ursodeoxycholic acid impairs liver‐infiltrating T‐cell chemotaxis through IFN‐γ and CX3CL1 production in primary biliary cholangitis10
Guidelines for standardizing T‐cell cytometry assays to link biomarkers, mechanisms, and disease outcomes in type 1 diabetes10
TRIM10 binds to IFN‐α/β receptor 1 to negatively regulate type I IFN signal transduction10
Augmented neutralization of SARS‐CoV‐2 Omicron variant by boost vaccination and monoclonal antibodies10
Macrophage plasticity as a therapeutic target in tuberculosis10
Hydroxychloroquine inhibits proteolytic processing of endogenous TLR7 protein in human primary plasmacytoid dendritic cells10
Human myeloid‐derived suppressor cell expansion during sepsis is revealed by unsupervised clustering of flow cytometric data10
Profiling the specificity of clonally expanded plasma cells during chronic viral infection by single‐cell analysis10
Hobit and Blimp‐1 regulate TRM abundance after LCMV infection by suppressing tissue exit pathways of TRMprecursors9
Effect of everolimus‐based drug regimens on CMV‐specific T‐cell functionality after renal transplantation: 12‐month ATHENA subcohort‐study results9
TFF3 mediates the NF‐κB/COX2 pathway to regulate PMN‐MDSCs activation and protect against necrotizing enterocolitis9
Guidelines for visualization and analysis of DC in tissues using multiparameter fluorescence microscopy imaging methods9
Checkpoints controlling the induction of B cell mediated autoimmunity in human autoimmune diseases9
Migration of murine intestinal dendritic cell subsets upon intrinsic and extrinsic TLR3 stimulation9
SARS‐CoV‐2‐specific T cells are generated in less than half of allogeneic HSCT recipients failing to seroconvert after COVID‐19 vaccination9
Cross‐presentation of dead‐cell‐associated antigens by DNGR‐1+ dendritic cells contributes to chronic allograft rejection in mice9
Dysregulated RASGRP1 expression through RUNX1 mediated transcription promotes autoimmunity9
Plasmacytoid dendritic cells regulate host immune response to Citrobacter rodentium induced colitis in colon‐draining lymph nodes9
Stereotyped B‐cell responses are linked to IgG constant region polymorphisms in multiple sclerosis9
CD11c identifies microbiota and EGR2‐dependent MHCII+ serous cavity macrophages with sexually dimorphic fate in mice9
Altered follicular regulatory T (Tfr)‐ and helper T (Tfh)‐cell subsets are associated with autoantibody levels in microscopic polyangiitis patients9
Autoantibodies targeting type I interferons: Prevalence, mechanisms of induction, and association with viral disease susceptibility9
COVID‐19 rapidly increases MDSCs and prolongs innate immune dysfunctions9
Follicular helper T cell signature of replicative exhaustion, apoptosis, and senescence in common variable immunodeficiency9
GVHD, IBD, and primary immunodeficiencies: The gut as a target of immunopathology resulting from impaired immunity8
Phospholipase activity of acyloxyacyl hydrolase induces IL‐22‐producing CD1a‐autoreactive T cells in individuals with psoriasis8
Epigenetic regulation in antiviral innate immunity8
Epstein Barr virus infection and immune defense related to HLA‐DR15: consequences for multiple sclerosis8
A conserved pathway of transdifferentiation in murine Kupffer cells8
Resolving trained immunity with systems biology8
Interleukin‐21 in autoimmune and inflammatory skin diseases8
Type I interferon receptor signalling deficiency results in dysregulated innate immune responses to SARS‐CoV‐2 in mice8
Nurse shark T‐cell receptors employ somatic hypermutation preferentially to alter alpha/delta variable segments associated with alpha constant region8
Single‐cell resolution of plasma cell fate programming in health and disease8
Genetic dissection of a major haplotype associated with arthritis reveal FcγR2b and FcγR3 to act additively8
TNFR2 expression is a hallmark of human memory B cells with suppressive function8
Successful treatment of COVID‐19 infection with convalescent plasma in B‐cell‐depleted patients may promote cellular immunity8
UNC93B1 curbs cytosolic DNA signaling by promoting STING degradation8
Acquisition of human plasminogen facilitates complement evasion by the malaria parasite Plasmodium falciparum8
Fa(c)t checking: How fatty acids shape metabolism and function of macrophages and dendritic cells8
Induction of diverse T cell memory through antibody‐mediated activation in mice8
Commensal fungi and their cell‐wall β‐glucans direct differential responses in human intestinal epithelial cells8
Human T cells interacting with HNSCC‐derived mesenchymal stromal cells acquire tissue‐resident memory like properties8
Nitrosonisoldipine is a selective inhibitor of inflammatory caspases and protects against pyroptosis and related septic shock8
SARS‐CoV‐2‐reactive T‐cell receptors isolated from convalescent COVID‐19 patients confer potent T‐cell effector function8
Th17 lymphocyte‐dependent degradation of joint cartilage by synovial fibroblasts in a humanized mouse model of arthritis and reversal by secukinumab8
Multiomics uncovers developing immunological lineages in human8
CD8+ T cells are crucial for humoral immunity establishment by SA14‐14‐2 live attenuated Japanese encephalitis vaccine in mice8
Robust intrathymic development of regulatory T cells in young NOD mice is rapidly restrained by recirculating cells8
Emerging imaging and liquid biomarkers in multiple sclerosis7
P2X7 is expressed on human innate‐like T lymphocytes and mediates susceptibility to ATP‐induced cell death7
T helper cell subsets: diversification of the field7
Regulatory T cells and transplantation tolerance: Emerging from the darkness?7
Peptidylprolyl isomerase C (Ppic) regulates invariant Natural Killer T cell (iNKT) differentiation in mice7
Murine iNKT cells are depleted by liver damage via activation of P2RX77
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