OOIR: Observatory of International Research

Papers

(The TQCC of European Journal of Immunology is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Impressum	118
Impressum	96
Transglutaminase 2 affinity and enzyme‐substrate intermediate stability as determining factors for T‐cell responses to gluten peptides in celiac disease	68
Linking Epitope‐Specific T‐Cell Receptors to IFNγ Secretion Using Nanovial Technology	67
Surface CD69‐Negative CD4 and CD8 Bone Marrow‐Resident Human Memory T Cells	66
Fluorochrome‐labeled inhibitors of caspase‐1 require membrane permeabilization to efficiently access caspase‐1 in macrophages	60
The potential of γδ CAR and TRuC T cells: An unearthed treasure	54
Mast cells in type 2 skin inflammation: Maintenance and function	53
Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), 26–29 September, 2023, Strasbourg, France	51
Cover Story: Eur. J. Immunol. 4'23	49
Immunomodulation under the lens of real‐time in vivo imaging	47
Intrahepatic plasma cells, but not atypical memory B cells, associate with clinical phases of chronic hepatitis B	46
Emerging roles of host and microbial bioactive lipids in inflammatory bowel diseases	41
Immunoregulation of asthma by type 2 cytokine therapies: Treatments for all ages?	39
Epigenetic Regulation of CD8 ⁺ Effector T Cell Differentiation by PDCD5	36
Termination of CD40L co‐stimulation promotes human B cell differentiation into antibody‐secreting cells	36
TEAMwork: Interplay of Post‐Transcriptional Mechanisms, Epigenetics and Metabolism in (Auto‐)Immunity	36
Regulatory T cells as a therapeutic approach for inflammatory bowel disease	35
Four challenges to CAR T cells breaking the glass ceiling	34
In memoriam Martin Röllinghoff (1941–2022)	33
Immune signature of patients with cardiovascular disease predicts increased risk for a severe course of COVID‐19	32
Induction of Tolerogenic Dendritic Cells by a Noncoding Oligonucleotide	32
The Streptomyces Metabolite Thiostrepton Inhibits Regulatory T Cell Differentiation and Function to Boost Antitumor Immune Responses	31
Fate‐mapping studies in inbred mice: A model for understanding macrophage development and homeostasis?	31
Neutrophil subsets in noncancer liver diseases: Cellular crosstalk and therapeutic targets	30

Staphylococcus aureus ‐derived factors promote human Th9 cell polarization and enhance a transcriptional program associated with allergic inflammation	30
Sustained innate interferon is an essential inducer of tertiary lymphoid structures	30
Airway epithelial type‐2 alarmin profiles: Blood eosinophil counts remain in memory	30
Dimethyl itaconate selectively targets inflammatory and metabolic pathways in chronic lymphocytic leukemia	30
Guidelines for mouse and human DC functional assays	30
Bead‐by‐bead normalization of single antigen assays: A necessary step for accurate detection of weak anti‐HLA antibodies	29
The Phenotypical and Functional Effect of PGE2 on Human Macrophages	29
	29
Issue Information: Eur. J. Immunol. 1'25	28
Issue Information: Eur. J. Immunol. 8'23	28
In this issue	28
Cover Story: Eur. J. Immunol. 1'24	28
Communication and transparency at EJI: Supporting authors through their publishing experience	27
Current research and unmet needs in allergy and immunology in Germany: report presented by the DGfI and DGAKI task force Allergy & Immunology	26
The Young Immunologists' Podcast: Immunology and Much More	26
IQGAP1 Influences Neutrophil Maturation and Its Effector Functions	25
Immunomodulation of neutrophil granulocyte functions by bacterial polyphosphates	25
	24
Immediate major dynamic changes in the T‐ and NK‐cell subset composition after cardiac transplantation	24
Transcriptome–Proteome Analysis of Human Naive and Memory B Cell Subsets Reveals Isotype and Subclass‐Specific Phenotypes	24
T‐cell signature cytokines distinguish pulmonary sarcoidosis from pulmonary tuberculosis	23
AK2‐Deficient Mice Recapitulate Impaired Lymphopoiesis of Reticular Dysgenesis Patients, but Also Lack Erythropoiesis	23
Mouse dendritic cells and other myeloid subtypes in healthy lymph nodes and skin: 26‐Color flow cytometry panel for immune phenotyping	23
Researcher Reflections—Inspiring Paths in Academia	22
Czech Young Immunologists: Bound by science, united in purpose	22
Potentiation of the axis involving pentose phosphate pathway/NADPH oxidase/reactive oxygen species drives higher IL‐10 production in monocytes of Sub‐Saharan Africans	22
Cytokine Autoantibodies Alter Gene Expression Profiles of Healthy Donors	22
The VEGF‐Mediated Cytoprotective Ability of MIF‐Licensed Mesenchymal Stromal Cells in House Dust Mite‐Induced Epithelial Damage	21
Functional Fc receptors are crucial in antibody‐mediated protection against cytomegalovirus	21
Paradoxical immunodeficiencies—When failures of innate immunity cause immunopathology	21
Key actors in neuropathophysiology: The role of γδ T cells	21
Mastering Immunity: Antibody Feedback as a Driver of Germinal Center Fate and Vaccine Responses	20
Hyperinflammation by Human Macrophages Induced by SARS‐CoV‐2 Anti‐Spike IgG Is Dependent on Glucose and Fatty Acid Metabolism	20
Charting Bird Tregs	20
IL‐4, IL‐15, and Type I Interferon Orchestrate the Shaping of the Heterogeneity of Virtual Memory CD8 T Cells	20
YF17D‐based vaccines – standing on the shoulders of a giant	20
Innate immunity champions: The diverse functions of macrophages	19
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TLR9‐Driven S‐Palmitoylation in Dendritic Cells Reveals Immune and Metabolic Protein Targets	19
Fully functional monocytic MDSC generation from the murine HoxB8 cell line	19
Enhanced in vitro type 1 conventional dendritic cell generation via the recruitment of hematopoietic stem cells and early progenitors by Kit ligand	19
Novel homozygous CD46 variant with C‐isoform expression affects C3b inactivation in atypical hemolytic uremic syndrome	18
EFIS News	18
Contents: Eur. J. Immunol. 11'22	18
Contents: Eur. J. Immunol. 7'22	18
Impressum	18
In this issue	18
Journal roundup	18
Impressum	18
Immunology meeting	18

Langerhans cells orchestrate apoptosis of DNA‐damaged keratinocytes upon high‐dose UVB skin exposure	18
Tyrosine kinase inhibitor cabozantinib impacts dendritic and natural killer cells immune response in C38 syngeneic tumor model	17
Single‐cell multi‐omics analysis of COVID‐19 patients with pre‐existing autoimmune diseases shows aberrant immune responses to infection	17
Sex‐specific impact of psychosocial stress on hematopoiesis and blood leukocytes	17
Release of IL‐1β and IL‐18 in human primary bronchial epithelial cells exposed to cigarette smoke is independent of NLRP3	17
B Cell Receptor Repertoire Analysis of the CD21 ^lo B Cell Compartment in Healthy Individuals, Patients With Sjögren's Disease, and Patients With Radi	17
Dendritic cells generated from induced pluripotent stem cells and by direct reprogramming of somatic cells	17
Microenvironmental signals shaping NK‐cell reactivity in cancer	17
MicroRNA‐146a deficiency enhances host protection against murine cytomegalovirus	17
Pamidronate‐Induced Clinical Remission in Chronic Non‐bacterial Osteomyelitis Is Associated with Reduced Vγ9Vδ2 T‐Cell Receptor Expression	17
Differential regulation of CD8 ⁺ CD86 ⁺ Vγ1.1 ⁺	17
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The immunosuppressive drug cyclosporin A has an immunostimulatory function in CD8 ⁺ T cells	17
Knockout of SLy1 decreases double‐negative thymocyte proliferation and protects mice from p53‐induced tumor formation	17
Differential Runx3, Eomes, and T‐bet expression subdivides MS‐associated CD4 ⁺ T cells with brain‐homing capacity	16
Acquired immune resistance is associated with interferon signature and modulation of KLF6/c‐MYB transcription factors in myeloid leukemia	16
Guidelines for mouse and human DC generation	16
Distinct Tissue‐Dependent Composition and Gene Expression of Human Fetal Innate Lymphoid Cells	16
Endogenous secretory leukocyte protease inhibitor inhibits microbial‐induced monocyte activation	16
Issue Information: Eur. J. Immunol. 12'25	16
PP2A catalytic subunit alpha is critically required for CD8 ⁺ T‐cell homeostasis and antibacterial responses	16
Exploring How Cytoskeleton Dynamics Tunes T Cell Activation at the Immunological Synapse	16
Expanding our understanding of Guillain–Barré syndrome: Recent advances and clinical implications	16
The Swiss Young Immunologists Society (SYIS): Empowering the next generation of immunologists	16
Nonreplicating synthetic mRNA vaccines: A journey through the European (Journal of Immunology) history	15
EXPRESSION OF CONCERN: Activation of Epstein‐Barr Virus/C3d Receptor (gp140, CR2, CD21) on Human Cell Surface Triggers pp60src and Akt‐GSK3 Activities Upstream and Downstream to PI 3‐Kinase, Respectiv	15
Cover story: Eur. J. Immunol. 7'22	15
SIRPα: A key player in innate immunity	15
Methiothepin downregulates SNAP‐23 and inhibits degranulation of rat basophilic leukemia cells and mouse bone marrow‐derived mast cells	15
Intestinal homeostasis and inflammation: Gut microbiota at the crossroads of pancreas–intestinal barrier axis	15
	15
DsbA‐L deletion attenuates LPS‐induced acute kidney injury by modulating macrophage polarization	15
Correction	15
Issue Information: Eur. J. Immunol. 7'23	15
Human Blood IgA ⁺ Memory B Cells Differ From IgG ⁺ B Cells by Expressing Gut‐Homing and Regulatory	15
	15
Cover Story: Eur. J. Immunol. 12'23	15
A human immune system (HIS) mouse model that dissociates roles for mouse and human FcR⁺ cells during antibody‐mediated immune responses	15
Proteomics reveals a global phenotypic shift of NK cells in HCV patients treated with direct‐acting antivirals	14
Resolution of Autoimmune Uveitis Requires CCL20‐Dependent Regulatory T Cells	14
From simple to complex: Protein‐based biomarker discovery in tuberculosis	14
Actinin‐4 controls survival signaling in B cells by limiting the lateral mobility of B‐cell antigen receptors	14
Bin‐based visualization of cytokine‐co‐expression patterns of IL‐10‐producing CD4 T cell subsets	14
Georg Friedrich (Fritz) Melchers (27.4.1936–24.2.2025)	14
Acellular Pertussis Vaccines Induce CD8 ⁺ and CD4 ⁺ Regulatory T Cells That Suppress Protective Ti	14
Imaging Mass Cytometry‐Based Immune Profiling of Human Peyer's Patches in Patients with Crohn's Disease	14
Human T Cell Responses to Flavivirus Vaccines	14
Therapeutic targeting of factor D and MASP3 in complement‐mediated diseases: Lessons learned from mouse studies	14
Diversity of regulatory B cells: Markers and functions	14
Interleukin‐2‐induced skin inflammation	14
Booster Injection with Birch Pollen Extract Activates B‐Cellular Memory Responses in Patients Having Completed Allergen Immunotherapy	14
Portuguese Society of Immunology (SPI): Turning 50, inspired by the past, looking into the future	13
B‐Cell Differentiation of Human Hematopoietic Progenitors Is Efficiently Supported by Wharton Jelly‐Derived Mesenchymal Stem Cells	13
Prophylactic Inhaled Pattern Recognition Receptor Agonists Reprogram Lung Epithelial Response and Prevent Type 2 Allergic Inflammation	13
CCR4 ⁺ CD8 ⁺ T cells clonally expand to differentiated effectors in murine psoriasis and in human	13
Impressum	13
Puppet masters of B‐cell progenitor acute lymphoblastic leukemia: The preB cell receptor and the interleukin 7 receptor α	13
Lymphotoxins from distinct types of lymphoid cells differentially contribute to neuroinflammation	13
Characterization of human CD4 ⁺ EOMES ⁺ GzmK ⁺	13
TNF Production or TNFR2 Expression Characterize Distinct States of Regulatory T Cells that Cooperate in Treg Expansion in Cancer and Chronic Inflammation	12
Inhibition of Melanoma Growth by Ex Vivo Expanded Tumor‐Specific CD8+ T Cells Is Dependent on the Configuration of Nanoscale Artificial APCs	12
Epigenetic Regulations in Autoimmunity and Cancer: from Basic Science to Translational Medicine	12
Effect of Aspirin Challenge on Innate Lymphoid Cells in Asthma Patients With Aspirin Hypersensitivity	12
Molecular and functional in vivo characterisation of murine Dectin‐1 isoforms	12
	12
Detection of dendritic cell subsets in the tumor microenvironment by multiplex immunohistochemistry	12
TLR4 phosphorylation at tyrosine 672 activates the ERK/c‐FOS signaling module for LPS‐induced cytokine responses in macrophages	12
	11
PIEZO1‐mediated mechanosensing governs NK‐cell killing efficiency and infiltration in three‐dimensional matrices	11
Antibiotic use during pregnancy is linked to offspring gut microbial dysbiosis, barrier disruption, and altered immunity along the gut–lung axis	11
Translational immunology: Applying fundamental discoveries to human health and autoimmune diseases	11
The first year of young group of the Spanish Immunology Society: Progress, challenges, and next steps	11
Effects of altered salt intake and diet on cytokines in humans: A 20‐week randomized cross‐over intervention study	11
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Impressum	11
Contents: Eur. J. Immunol. 8'22	11
Cover Story: Eur. J. Immunol. 5'24	11
Neural Crest‐Derived Mesenchymal Cells Support Thymic Reconstitution After Lethal Irradiation	11
Baseline Single‐Cell Differences in Polyfunctionality Between Systemic Autoinflammatory Diseases Patients and Healthy Controls	11

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Regulation of B‐cell function and expression of CD11c, T‐bet, and FcRL5 in response to different activation signals	11
Issue Information: Eur. J. Immunol. 1'23	11
Impressum	11
Immunogenicity‐Guided Design of an Acinetobacter baumanii Vaccine	11
Cover Story: Eur. J. Immunol. 8'23	11
Chronic stimulation desensitizes β2‐adrenergic receptor responses in natural killer cells	10
Survival of Human Bone Marrow Plasma Cells In Vitro Depends on the Support of the Stromal Cells, PI3K, and Canonical NF‐kappaB Signaling	10
Interleukin 23 receptor: Expression and regulation in immune cells	10
Autoimmunity and SARS‐CoV‐2 infection: Unraveling the link in neurological disorders	10
Retinoic acid‐loaded liposomes induce human mucosal CD103 ⁺ dendritic cells that inhibit Th17 cells and drive regulatory T‐cell development in vitro	10
TLR2 on CD4+ and CD8+ T cells promotes control of Mycobacterium tuberculosis infection	10
ICAP‐1 loss impairs CD8⁺ thymocyte development and leads to reduced marginal zone B cells in mice	10
Bystander activation of tissue‐resident memory CD4 T cells: Getting by with a little help from unfamiliar T‐cell friends	10
Single‐Cell Profiling of Splenic Immune Ageing and Chronic Stress Adaptations in Mice With Natural Microbiota	10
Vitamin A‐treated natural killer cells reduce interferon‐gamma production and support regulatory T‐cell differentiation	10
Microbial‐Immune Interplay in CNS Autoimmune Diseases: Lessons from Animal Models and Clinical Studies	10
In this issue	10
Crafting an MSCA PhD Masterpiece: Guiding Students on the Verge of Discovery	10
IL1R2 Acts as a Negative Regulator of Monocyte Recruitment During Inflammation	10
Upregulation of IL4‐induced gene 1 enzyme by B2 cells during melanoma progression impairs their antitumor properties	10
	10
38‐Marker Full‐Spectrum Flow Cytometry Panel for the Comprehensive Profiling of γδ T Cells in Human Blood and Lymphoid Tissues	10
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High Extracellular K ⁺ Skews T‐Cell Differentiation Towards Tumour Promoting Th2 and T _reg Subsets	10
Guidelines for DC preparation and flow cytometry analysis of mouse lymphohematopoietic tissues	10
yEFIS 1^st Symposium: Shaping the future of Immunology in Europe, 10–11 November, 2022, Berlin, Germany	10
Fine needle aspiration of human lymph nodes reveals cell populations and soluble interactors pivotal to immunological priming	9
Plasmodium berghei Radiation‐Attenuated Sporozoite‐Immunized Mice Require Infectious Sporozoite Challenge to Maintain Protective Immunity	9
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PD‐L2 Inhibits Protective Immunity, Th2 Cell Functional Quality, and GATA‐3 Expression During Filarial Nematode Infection	9
	9
Follicular helper T cell signature of replicative exhaustion, apoptosis, and senescence in common variable immunodeficiency	9
Combined Deletion of ZFP36L1 and ZFP36L2 Drives Superior Cytokine Production in T Cells at the Cost of Cell Fitness	9
Regulation of DC metabolism by nitric oxide in murine GM‐CSF cultures	9
Dendritic cells Trigger IFN‐γ secretion by NK cells independent of IL‐12 and IL‐18	9
yEFIS with EFIS Lead the Way to ECR Engagement at ECI2024	9
Cover Story: Eur. J. Immunol. 4'25	9
Characteristics and mechanisms of T‐cell senescence: A potential target for cancer immunotherapy	9
Trametinib Suppresses the Stimulated T Cells Through G1 Arrest and Apoptosis	9
Influence of SLAM Family Receptors in the NK‐Cell‐Mediated Surveillance of Lymphoblastic Acute Leukemia	9
ADAR1 Controls Macrophage Scavenging and Lipid‐Buffering Programs in Metabolic Tissues	9
T helper cell subsets: diversification of the field	9
CD4 ⁺ T‐Cell‐Intrinsic IL‐6 Is Critical for Th17 Differentiation and Dampened Responsiveness to CD8 ⁺	9
Polymorphism in F pocket affects peptide selection and stability of type 1 diabetes‐associated HLA‐B39 allotypes	9
Multifaceted Role of ILCs in Metabolic Adaptations: From Adult to Neonate	9
Prmt5 deficient mouse B cells display RNA processing complexity and slower colorectal tumor progression	9
Zfp362 potentiates murine colonic inflammation by constraining Treg cell function rather than promoting Th17 cell differentiation	9
Interferon α and β induce differential transcriptional and functional metabolic phenotypes in human macrophages and blunt glycolysis in response to antigenic stimuli	9
Impressum	9
PAD2 immunization induces ACPA in wild‐type and HLA‐DR4 humanized mice	9
Foxp3⁺ regulatory T cells in the central nervous system and other nonlymphoid tissues	9
Antigen‐Specific Tolerance: Clinical and Preclinical Approaches in Autoimmunity	8
Sphingosine‐1‐phosphate receptor type 4 is critically involved in the regulation of peritoneal B‐1 cell trafficking and distribution in vivo	8
Impact of the adenosine receptor A2BR expressed on myeloid cells on immune regulation during pregnancy	8
Cover Story: Eur. J. Immunol. 8'24	8
Identification and Mapping of Human Lymph Node Stromal Cell Subsets by Combining Single‐Cell RNA Sequencing with Spatial Transcriptomics	8
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Autoantibodies targeting type I interferons: Prevalence, mechanisms of induction, and association with viral disease susceptibility	8
Rational design of polymer‐based particulate vaccine adjuvants	8
Ccl21a , Rather Than Ccl21b , is Essential for Thymocyte Migration in Mouse	8
Immunity in malignant brain tumors: Tumor entities, role of immunotherapy, and specific contribution of myeloid cells to the brain tumor microenvironment	8
CD95L concatemers highlight different stoichiometries of CD95‐mediated apoptotic and nonapoptotic pathways	8
Sensing context: Inhibitory receptors on non‐hematopoietic cells	8
Cover Story: Eur. J. Immunol. 11'23	8
Impressum	8
MicroRNAs targeting TGF‐β signaling exacerbate central nervous system autoimmunity by disrupting regulatory T cell development and function	8
Therapeutic tactics for targeting B lymphocytes in autoimmunity and cancer	8
TOX Does Not Drive Sepsis‐Induced T‐Cell Exhaustion	8
Meeting Report: German–Japanese Alliance in Immunology	8
Front cover story: Eur. J. Immunol. 11'22	8
FcµR and IgM‐Mediated Complement Activation Cooperate to Enhance Humoral Immunity	8
The complement system: A key player in the host response to infections	8
Composition of fatty acids in a high‐fat diet affects adipose tissue inflammation by inducing calreticulin on adipocytes and activating group 1 innate lymphoid cells	8
Antibody density on bacteria regulates C1q recruitment by monoclonal IgG but not IgM	8
Deciphering the Human Germinal Center: A Review of Models to Study T–B Cell Interactions	8
Cover Story: Eur. J. Immunol. 4'24	8
Issue Information: Eur. J. Immunol. 5'25	8
GPR109A expressed on medullary thymic epithelial cells affects thymic Treg development	8
SARS‐CoV‐2 variants of concern elicit divergent early immune responses in hACE2 transgenic mice	8
Verteporfin protects against Th17 cell‐mediated EAE independently of YAP inhibition	8
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Synovial Tissue Macrophage Heterogeneity in Rheumatoid Arthritis	8
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Bile acid‐activated receptors in innate and adaptive immunity: targeted drugs and biological agents	7
Training the microbiota to increase immune checkpoint blockade and to reduce toxicity	7
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VSIG4‐Expressing Macrophages Contribute to Antiparasitic and Antimetastatic Responses in the Peritoneal Cavity	7
Issue Information: Eur. J. Immunol. 12'24	7
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Transcriptional Regulation of Macrophage Specification and Function	7
Advances in experimental models of rheumatoid arthritis	7
EFIS Board 2024–2027: New Leadership for Advancing Immunology in Europe	7
Immunological Impact of Oncolytic Adenoviruses On Cancer Therapy: Clinical Insights	7