OOIR: Observatory of International Research

Papers

(The median citation count of European Journal of Immunology is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Transglutaminase 2 affinity and enzyme‐substrate intermediate stability as determining factors for T‐cell responses to gluten peptides in celiac disease	346
Impressum	77
Inborn errors of immunity and immunodeficiencies: Antibody‐mediated pathology and autoimmunity as a consequence of impaired immune reactions	74
Impressum	74
A pair of noncompeting neutralizing human monoclonal antibodies protecting from disease in a SARS‐CoV‐2 infection model	71
Integrin activation enables rapid detection of functional Vδ1⁺ and Vδ2⁺ γδ T cells	67
B‐cell modulation with anti‐CD79b antibodies ameliorates experimental autoimmune encephalitis in mice	59
Metabolic dynamics instruct CD8⁺ T‐cell differentiation and functions	56
Termination of CD40L co‐stimulation promotes human B cell differentiation into antibody‐secreting cells	55
Cover Story: Eur. J. Immunol. 4'23	52
Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), 26–29 September, 2023, Strasbourg, France	52
Intrahepatic plasma cells, but not atypical memory B cells, associate with clinical phases of chronic hepatitis B	46
The potential of γδ CAR and TRuC T cells: An unearthed treasure	45
Sustained innate interferon is an essential inducer of tertiary lymphoid structures	44
Bead‐by‐bead normalization of single antigen assays: A necessary step for accurate detection of weak anti‐HLA antibodies	39
Issue Information: Eur. J. Immunol. 10'21	39
Immunomodulation under the lens of real‐time in vivo imaging	38
Immunoregulation of asthma by type 2 cytokine therapies: Treatments for all ages?	38
Fate‐mapping studies in inbred mice: A model for understanding macrophage development and homeostasis?	37
Staphylococcus aureus‐derived factors promote human Th9 cell polarization and enhance a transcriptional program associated with allergic inflammation	37
Guidelines for mouse and human DC functional assays	36
Regulatory T cells as a therapeutic approach for inflammatory bowel disease	33
Neutrophil subsets in noncancer liver diseases: Cellular crosstalk and therapeutic targets	31
Mast cells in type 2 skin inflammation: Maintenance and function	31
Airway epithelial type‐2 alarmin profiles: Blood eosinophil counts remain in memory	31

In memoriam Martin Röllinghoff (1941–2022)	30
Fluorochrome‐labeled inhibitors of caspase‐1 require membrane permeabilization to efficiently access caspase‐1 in macrophages	30
Dimethyl itaconate selectively targets inflammatory and metabolic pathways in chronic lymphocytic leukemia	30
Surface CD69‐Negative CD4 and CD8 Bone Marrow‐Resident Human Memory T Cells	29
Immune signature of patients with cardiovascular disease predicts increased risk for a severe course of COVID‐19	28
Four challenges to CAR T cells breaking the glass ceiling	28
Epigenetic Regulation of CD8⁺ Effector T Cell Differentiation by PDCD5	28
Emerging roles of host and microbial bioactive lipids in inflammatory bowel diseases	28
Linking Epitope‐Specific T‐Cell Receptors to IFNγ Secretion Using Nanovial Technology	28
	28
Current research and unmet needs in allergy and immunology in Germany: report presented by the DGfI and DGAKI task force Allergy & Immunology	27
In this issue	27
E‐Cadherin restricts mast cell degranulation in mice	27
LCMV induced downregulation of HVEM on antiviral T cells is critical for an efficient effector response	26
BOB.1/OBF.1 is required during B‐cell ontogeny for B‐cell differentiation and germinal center function	26
Global k_off‐rates of polyclonal T‐cell populations merge subclonal avidities and predict functionality	26
MHC class I molecules co‐stimulate NK1.1 signaling and enhance Ca²⁺ flux in murine NK cells	26
Cereblon regulates NK cell cytotoxicity and migration via Rac1 activation	26
	26
Paradoxical immunodeficiencies—When failures of innate immunity cause immunopathology	26
Metabolic reprograming shapes neutrophil functions in severe COVID‐19	25
Functional Fc receptors are crucial in antibody‐mediated protection against cytomegalovirus	25
Mouse dendritic cells and other myeloid subtypes in healthy lymph nodes and skin: 26‐Color flow cytometry panel for immune phenotyping	25
Key actors in neuropathophysiology: The role of γδ T cells	24
Potentiation of the axis involving pentose phosphate pathway/NADPH oxidase/reactive oxygen species drives higher IL‐10 production in monocytes of Sub‐Saharan Africans	24
Innate immunity champions: The diverse functions of macrophages	23
The VEGF‐Mediated Cytoprotective Ability of MIF‐Licensed Mesenchymal Stromal Cells in House Dust Mite‐Induced Epithelial Damage	23
Cytokine Autoantibodies Alter Gene Expression Profiles of Healthy Donors	23
Issue Information: Eur. J. Immunol. 1'25	22
IL‐4, IL‐15, and Type I Interferon Orchestrate the Shaping of the Heterogeneity of Virtual Memory CD8 T Cells	22
Cover Story: Eur. J. Immunol. 1'24	21
Enhanced in vitro type 1 conventional dendritic cell generation via the recruitment of hematopoietic stem cells and early progenitors by Kit ligand	21
Researcher Reflections—Inspiring Paths in Academia	21
YF17D‐based vaccines – standing on the shoulders of a giant	21
T‐cell signature cytokines distinguish pulmonary sarcoidosis from pulmonary tuberculosis	20
IQGAP1 Influences Neutrophil Maturation and Its Effector Functions	19
The Young Immunologists' Podcast: Immunology and Much More	18
Czech Young Immunologists: Bound by science, united in purpose	18
Communication and transparency at EJI: Supporting authors through their publishing experience	18
Immunomodulation of neutrophil granulocyte functions by bacterial polyphosphates	18
Issue Information: Eur. J. Immunol. 8'23	18
Immediate major dynamic changes in the T‐ and NK‐cell subset composition after cardiac transplantation	17
Novel homozygous CD46 variant with C‐isoform expression affects C3b inactivation in atypical hemolytic uremic syndrome	17
AK2‐Deficient Mice Recapitulate Impaired Lymphopoiesis of Reticular Dysgenesis Patients, but Also Lack Erythropoiesis	17
Contents: Eur. J. Immunol. 11'22	17
Fully functional monocytic MDSC generation from the murine HoxB8 cell line	17
	17
Differential regulation of CD8⁺CD86⁺ Vγ1.1⁺ γδT cell responses in skin barrier tissue protection and homeostatic maintenance	17
Contents: Eur. J. Immunol. 7'22	16
Dendritic cells generated from induced pluripotent stem cells and by direct reprogramming of somatic cells	16

Hyperlipidemia‐induced metabolic changes in regulatory T cells result in altered function	16
Contents: Eur. J. Immunol. 12'21	16
	16
Altered increase in STAT1 expression and phosphorylation in severe COVID‐19	16
In this issue	16
Journal roundup	16
	16
PP2A catalytic subunit alpha is critically required for CD8⁺ T‐cell homeostasis and antibacterial responses	15
Impressum	15
Helios is a marker, not a driver, of human Treg stability	15
MicroRNA‐146a deficiency enhances host protection against murine cytomegalovirus	15
Pamidronate‐Induced Clinical Remission in Chronic Non‐bacterial Osteomyelitis Is Associated with Reduced Vγ9Vδ2 T‐Cell Receptor Expression	15
Intestinal homeostasis and inflammation: Gut microbiota at the crossroads of pancreas–intestinal barrier axis	15
B Cell Receptor Repertoire Analysis of the CD21^lo B Cell Compartment in Healthy Individuals, Patients With Sjögren's Disease, and Patients With Radiographic Axial Spondyloarthritis	15
Distinct Tissue‐Dependent Composition and Gene Expression of Human Fetal Innate Lymphoid Cells	15
Human cDC1s display constitutive activation of the UPR sensor IRE1	15
Impressum	14
The immunosuppressive drug cyclosporin A has an immunostimulatory function in CD8⁺ T cells	14
Differential Runx3, Eomes, and T‐bet expression subdivides MS‐associated CD4⁺ T cells with brain‐homing capacity	14
Acquired immune resistance is associated with interferon signature and modulation of KLF6/c‐MYB transcription factors in myeloid leukemia	14
Single‐cell multi‐omics analysis of COVID‐19 patients with pre‐existing autoimmune diseases shows aberrant immune responses to infection	14
The Swiss Young Immunologists Society (SYIS): Empowering the next generation of immunologists	14
Immunology meeting	13
Langerhans cells orchestrate apoptosis of DNA‐damaged keratinocytes upon high‐dose UVB skin exposure	13
DsbA‐L deletion attenuates LPS‐induced acute kidney injury by modulating macrophage polarization	13
Endogenous secretory leukocyte protease inhibitor inhibits microbial‐induced monocyte activation	13
	13
Microenvironmental signals shaping NK‐cell reactivity in cancer	13
In this issue	13
Nonreplicating synthetic mRNA vaccines: A journey through the European (Journal of Immunology) history	13
Tyrosine kinase inhibitor cabozantinib impacts dendritic and natural killer cells immune response in C38 syngeneic tumor model	13
Expanding our understanding of Guillain–Barré syndrome: Recent advances and clinical implications	13
	13
EFIS News	13
Sex‐specific impact of psychosocial stress on hematopoiesis and blood leukocytes	13
Guidelines for mouse and human DC generation	13
Knockout of SLy1 decreases double‐negative thymocyte proliferation and protects mice from p53‐induced tumor formation	13
Release of IL‐1β and IL‐18 in human primary bronchial epithelial cells exposed to cigarette smoke is independent of NLRP3	13
Correction	13
Cover Story: Eur. J. Immunol. 12'23	12
Diversity of regulatory B cells: Markers and functions	12
ACKR1 favors transcellular over paracellular T‐cell diapedesis across the blood‐brain barrier in neuroinflammation in vitro	12
Cover story: Eur. J. Immunol. 7'22	12
From simple to complex: Protein‐based biomarker discovery in tuberculosis	12
Acellular Pertussis Vaccines Induce CD8⁺ and CD4⁺ Regulatory T Cells That Suppress Protective Tissue‐Resident Memory CD4⁺ T Cells, in Part via IL‐10	12
Lymphotoxins from distinct types of lymphoid cells differentially contribute to neuroinflammation	12
Therapeutic targeting of factor D and MASP3 in complement‐mediated diseases: Lessons learned from mouse studies	12
SIRPα: A key player in innate immunity	12
Augmented neutralization of SARS‐CoV‐2 Omicron variant by boost vaccination and monoclonal antibodies	12
Mutant B2M‐HLA‐E and B2M‐HLA‐G fusion proteins protects universal chimeric antigen receptor‐modified T cells from allogeneic NK cell‐mediated lysis	12
A human immune system (HIS) mouse model that dissociates roles for mouse and human FcR⁺ cells during antibody‐mediated immune responses	12
Resolution of Autoimmune Uveitis Requires CCL20‐Dependent Regulatory T Cells	12
In this issue	12
Actinin‐4 controls survival signaling in B cells by limiting the lateral mobility of B‐cell antigen receptors	12
Methiothepin downregulates SNAP‐23 and inhibits degranulation of rat basophilic leukemia cells and mouse bone marrow‐derived mast cells	12
Proteomics reveals a global phenotypic shift of NK cells in HCV patients treated with direct‐acting antivirals	12
SARS‐CoV‐2‐specific T cells are generated in less than half of allogeneic HSCT recipients failing to seroconvert after COVID‐19 vaccination	12
Bin‐based visualization of cytokine‐co‐expression patterns of IL‐10‐producing CD4 T cell subsets	12
Interleukin‐2‐induced skin inflammation	12
Georg Friedrich (Fritz) Melchers (27.4.1936–24.2.2025)	12
Issue Information: Eur. J. Immunol. 7'23	12
Specificity of mouse and human Fcgamma receptors and their polymorphic variants for IgG subclasses of different species	11
Impressum	11
Detection of dendritic cell subsets in the tumor microenvironment by multiplex immunohistochemistry	11
Bruton's tyrosine kinase inhibition induces rewiring of proximal and distal B‐cell receptor signaling in mice	11
Regulation of B‐cell function and expression of CD11c, T‐bet, and FcRL5 in response to different activation signals	11
Antibiotic use during pregnancy is linked to offspring gut microbial dysbiosis, barrier disruption, and altered immunity along the gut–lung axis	11
TLR4 phosphorylation at tyrosine 672 activates the ERK/c‐FOS signaling module for LPS‐induced cytokine responses in macrophages	11
Characterization of human CD4⁺EOMES⁺GzmK⁺ T‐cell subsets unveils an uncoupling of suppressive functions from IL‐10‐producing capacities	11
Puppet masters of B‐cell progenitor acute lymphoblastic leukemia: The preB cell receptor and the interleukin 7 receptor α	11
Molecular and functional in vivo characterisation of murine Dectin‐1 isoforms	11
Inhibition of Melanoma Growth by Ex Vivo Expanded Tumor‐Specific CD8+ T Cells Is Dependent on the Configuration of Nanoscale Artificial APCs	11
CCR4⁺CD8⁺ T cells clonally expand to differentiated effectors in murine psoriasis and in human psoriatic arthritis	11
Portuguese Society of Immunology (SPI): Turning 50, inspired by the past, looking into the future	11
Epigenetic Regulations in Autoimmunity and Cancer: from Basic Science to Translational Medicine	11
Impressum	11
Characterization of SARS‐CoV‐2 and common cold coronavirus‐specific T‐cell responses in MIS‐C and Kawasaki disease children	10
Compartmentalized multicellular crosstalk in lymph nodes coordinates the generation of potent cellular and humoral immune responses	10
	10
Bystander activation of tissue‐resident memory CD4 T cells: Getting by with a little help from unfamiliar T‐cell friends	10

Front cover story: Eur. J. Immunol. 2'22	10
Upregulation of IL4‐induced gene 1 enzyme by B2 cells during melanoma progression impairs their antitumor properties	10
Autoimmunity and SARS‐CoV‐2 infection: Unraveling the link in neurological disorders	10
PIEZO1‐mediated mechanosensing governs NK‐cell killing efficiency and infiltration in three‐dimensional matrices	10
	10
PDGFRα‐lineage origin directs monocytes to trafficking proficiency to support peripheral immunity	10
Interleukin 23 receptor: Expression and regulation in immune cells	10
The first year of young group of the Spanish Immunology Society: Progress, challenges, and next steps	10
Retinoic acid‐loaded liposomes induce human mucosal CD103⁺ dendritic cells that inhibit Th17 cells and drive regulatory T‐cell development in vitro	10
	10
Contents: Eur. J. Immunol. 8'22	10
Impressum	10
	10
Vitamin A‐treated natural killer cells reduce interferon‐gamma production and support regulatory T‐cell differentiation	10
TLR2 on CD4+ and CD8+ T cells promotes control of Mycobacterium tuberculosis infection	10
Issue Information: Eur. J. Immunol. 1'23	10
Cover Story: Eur. J. Immunol. 8'23	9
Foxp3⁺ regulatory T cells in the central nervous system and other nonlymphoid tissues	9
Impressum	9
yEFIS 1^st Symposium: Shaping the future of Immunology in Europe, 10–11 November, 2022, Berlin, Germany	9
Immunogenicity‐Guided Design of an Acinetobacter baumanii Vaccine	9
ICAP‐1 loss impairs CD8⁺ thymocyte development and leads to reduced marginal zone B cells in mice	9
Guidelines for DC preparation and flow cytometry analysis of mouse lymphohematopoietic tissues	9
Survival of Human Bone Marrow Plasma Cells In Vitro Depends on the Support of the Stromal Cells, PI3K, and Canonical NF‐kappaB Signaling	9
Crafting an MSCA PhD Masterpiece: Guiding Students on the Verge of Discovery	9
	9
Effects of altered salt intake and diet on cytokines in humans: A 20‐week randomized cross‐over intervention study	9
6^th European Congress of Immunology, 1–4 September 2021, Virtual meeting	9
T helper cell subsets: diversification of the field	9
Dendritic cells Trigger IFN‐γ secretion by NK cells independent of IL‐12 and IL‐18	9
Cover Story: Eur. J. Immunol. 5'24	9
Translational immunology: Applying fundamental discoveries to human health and autoimmune diseases	9
High Extracellular K⁺ Skews T‐Cell Differentiation Towards Tumour Promoting Th2 and T_reg Subsets	9
Chronic stimulation desensitizes β2‐adrenergic receptor responses in natural killer cells	9
In this issue	9
	9
Regulation of DC metabolism by nitric oxide in murine GM‐CSF cultures	9
IL1R2 Acts as a Negative Regulator of Monocyte Recruitment During Inflammation	9
Neural Crest‐Derived Mesenchymal Cells Support Thymic Reconstitution After Lethal Irradiation	9
Characteristics and mechanisms of T‐cell senescence: A potential target for cancer immunotherapy	8
yEFIS with EFIS Lead the Way to ECR Engagement at ECI2024	8
Combined Deletion of ZFP36L1 and ZFP36L2 Drives Superior Cytokine Production in T Cells at the Cost of Cell Fitness	8
Zfp362 potentiates murine colonic inflammation by constraining Treg cell function rather than promoting Th17 cell differentiation	8
	8
PAD2 immunization induces ACPA in wild‐type and HLA‐DR4 humanized mice	8
Altered IgG glycosylation at COVID‐19 diagnosis predicts disease severity	8
SARS‐CoV‐2 variants of concern elicit divergent early immune responses in hACE2 transgenic mice	8
Impressum	8
Cover Story: Eur. J. Immunol. 4'25	8
Follicular helper T cell signature of replicative exhaustion, apoptosis, and senescence in common variable immunodeficiency	8
Trametinib Suppresses the Stimulated T Cells Through G1 Arrest and Apoptosis	8
Prmt5 deficient mouse B cells display RNA processing complexity and slower colorectal tumor progression	8
	8
Verteporfin protects against Th17 cell‐mediated EAE independently of YAP inhibition	8
Ex vivo microRNA and gene expression profiling of human Tr1‐like cells suggests a role for miR‐92a and ‐125a in the regulation of EOMES and IL‐10R	8
Sensing context: Inhibitory receptors on non‐hematopoietic cells	8
Plasmodium berghei Radiation‐Attenuated Sporozoite‐Immunized Mice Require Infectious Sporozoite Challenge to Maintain Protective Immunity	8
Fine needle aspiration of human lymph nodes reveals cell populations and soluble interactors pivotal to immunological priming	8
Polymorphism in F pocket affects peptide selection and stability of type 1 diabetes‐associated HLA‐B39 allotypes	8
Interferon α and β induce differential transcriptional and functional metabolic phenotypes in human macrophages and blunt glycolysis in response to antigenic stimuli	8
MicroRNAs targeting TGF‐β signaling exacerbate central nervous system autoimmunity by disrupting regulatory T cell development and function	8
Dynamics of IL‐15/IL‐15R‐α expression in response to HSV‐1 infection reveal a novel mode of viral immune evasion counteracted by iNKT cells	8
Autoantibodies targeting type I interferons: Prevalence, mechanisms of induction, and association with viral disease susceptibility	8
Rational design of polymer‐based particulate vaccine adjuvants	8
Antibody density on bacteria regulates C1q recruitment by monoclonal IgG but not IgM	7
GPR109A expressed on medullary thymic epithelial cells affects thymic Treg development	7
Impact of the adenosine receptor A2BR expressed on myeloid cells on immune regulation during pregnancy	7
TOX Does Not Drive Sepsis‐Induced T‐Cell Exhaustion	7
PBMC‐derived extracellular vesicles in a smoking‐related inflammatory disease model	7
	7
Impressum	7
VSIG4‐Expressing Macrophages Contribute to Antiparasitic and Antimetastatic Responses in the Peritoneal Cavity	7
In this issue	7
Early career immunology: A digital space to support early career investigators	7
Cover Story: Eur. J. Immunol. 4'24	7
Sphingosine‐1‐phosphate receptor type 4 is critically involved in the regulation of peritoneal B‐1 cell trafficking and distribution in vivo	7
CD95L concatemers highlight different stoichiometries of CD95‐mediated apoptotic and nonapoptotic pathways	7
Cover Story: Eur. J. Immunol. 11'23	7
	7
Front cover story: Eur. J. Immunol. 11'22	7
Training the microbiota to increase immune checkpoint blockade and to reduce toxicity	7
Issue Information: Eur. J. Immunol. 11'24	7
Cryptococcus gattii polysaccharide capsule: An insight on fungal‐host interactions and vaccine studies	7
Contents: Eur. J. Immunol. 1'22	7
Macrophage plasticity as a therapeutic target in tuberculosis	7
Cover Story: Eur. J. Immunol. 8'24	7
Composition of fatty acids in a high‐fat diet affects adipose tissue inflammation by inducing calreticulin on adipocytes and activating group 1 innate lymphoid cells	7
Therapeutic tactics for targeting B lymphocytes in autoimmunity and cancer	7
Identification and Mapping of Human Lymph Node Stromal Cell Subsets by Combining Single‐Cell RNA Sequencing with Spatial Transcriptomics	7
	7
Bile acid‐activated receptors in innate and adaptive immunity: targeted drugs and biological agents	7
Advances in experimental models of rheumatoid arthritis	7
PTEN is required for human Treg suppression of costimulation in vitro	7
Neutralizing antibodies to SARS‐CoV‐2 Omicron variant after third mRNA vaccination in health care workers and elderly subjects	7
	7