OOIR: Observatory of International Research

Papers

(The median citation count of European Journal of Immunology is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
	271
Crossing the barriers: Revisiting the gut feeling in rheumatoid arthritis	108
Blockade of OX40/OX40L signaling using anti‐OX40L alleviates murine lupus nephritis	103
Liver type 1 innate lymphoid cells undergo apoptosis in murine models of macrophage activation syndrome and are dispensable for disease	101
ThymoSpheres culture: A model to study human polyclonal unconventional T cells	68
Neutrophil subsets in noncancer liver diseases: Cellular crosstalk and therapeutic targets	67
Sustained innate interferon is an essential inducer of tertiary lymphoid structures	65
Immunization with excretory‐secretory molecules of intestinal nematodes induces antigen‐specific protective memory Th2 cell responses	63
Issue Information: Eur. J. Immunol. 6'22	58
In this issue	57
Protection against allergies: Microbes, immunity, and the farming effect	53
	52
Impressum	47
Front cover story: Eur. J. Immunol. 12'21	47
	45
Impressum	44
	43
Our latest edition of Flow Cytometry Guidelines for basic and clinical immunologists!	43
	40
Half a century of immunological discovery: EJI celebrates its golden anniversary!	40
	39
Journal roundup	39
Journal roundup	39
Impressum	39
Impressum	37

Young EFIS: Three years of progress – Reflecting on achievements and embracing new horizons	35
Agonistic anti‐CD27 antibody ameliorates EAE by suppressing IL‐17 production	34
Issue Information: Eur. J. Immunol. 10'21	34
Back cover story: Eur. J. Immunol. 10'21	33
Journal Round	33
EFIS and IUIS 2022 #DayofImmunology campaign	32
Impressum	32
Impressum	32
Importance of antibody isotypes in antitumor immunity by monocytes and complement using human‐immune tumor models	31
Regulation of autoimmune‐mediated neuroinflammation by endothelial cells	30
Frequency of natural regulatory T cells specific for factor VIII in the peripheral blood of healthy donors	30
SLAMF7 selectively favors degranulation to promote cytotoxicity in human NK cells	29
Nanoparticles for stimulation of neutrophil extracellular trap‐mediated immunity	29
2022 International Women's Day ‐ yEFIS highlights outstanding women vaccine researchers	28
Front cover story: Eur. J. Immunol. 4'22	28
Journal roundup	28
Back cover story: Eur. J. Immunol. 4'22	27
ICAP‐1 loss impairs CD8⁺ thymocyte development and leads to reduced marginal zone B cells in mice	27
Alterations of blood monocyte subset distribution and surface phenotype are linked to infection severity in COVID‐19 inpatients	27
Front cover story: Eur. J. Immunol. 3'22	26
Issue Information: Eur. J. Immunol. 3'22	26
Back cover story: Eur. J. Immunol. 4'21	26
RAG1/2 induces double‐stranded DNA breaks at non‐Ig loci in the proximity of single sequence repeats in developing B cells	26
Lung epithelial cells: Upstream targets in type 2‐high asthma	26
A surrogate cell‐based SARS‐CoV‐2 spike blocking assay	25
IL‐27 mediates anti‐inflammatory effect in cigarette smoke induced emphysema by negatively regulating IFN‐γ producing cytotoxic CD8⁺T cells in mice	24
Dendritic cells Trigger IFN‐γ secretion by NK cells independent of IL‐12 and IL‐18	24
Prmt5 deficient mouse B cells display RNA processing complexity and slower colorectal tumor progression	23
Vγ6⁺ γδ T cells are critical for protection against infection by Escherichia coli in mice	23
Peripheral differentiation patterns of human T cells	23
Point mutation L116R in interferon‐regulatory factor 4 differentially impacts key cytokine production in Th2, Th9, and Th17 cells	22
Inborn errors of immunity and immunodeficiencies: Antibody‐mediated pathology and autoimmunity as a consequence of impaired immune reactions	22
IL‐18: A potential inflammation biomarker in Wiskott–Aldrich syndrome	22
cIAP1/2 antagonization by SMAC mimetic induces non‐canonical NF‐κB mediated T_H17 cell homotypic interactions and increases their resistance to shear stress	21
Regulation of DC metabolism by nitric oxide in murine GM‐CSF cultures	21
Glycolytic metabolite phosphoenolpyruvate protects host from viral infection through promoting AATK expression	21
Immunoregulation of asthma by type 2 cytokine therapies: Treatments for all ages?	21
Sepsis shapes the human γδ TCR repertoire in an age‐ and pathogen‐dependent manner	20
Small molecule inhibitors targeting regulatory T cells for cancer treatment	20
Toll‐like receptor 3 expression in myeloid cells is essential for efficient regeneration after acute pancreatitis in mice	20
16^th ENII‐EFIS‐EJI Summer School on Advanced Immunology	20
Antibodies internalization mechanisms by dendritic cells and their role in therapeutic antibody immunogenicity	20
Development of Plasmodium‐specific liver‐resident memory CD8⁺ T cells after heat‐killed sporozoite immunization in mice	20
The EFIS vaccination task force expert report	20
Influenza A virus‐induced thymus atrophy differentially affects dynamics of conventional and regulatory T‐cell development in mice	20
T‐cell selection in the thymus: New routes toward the identification of the self‐peptide ligandome presented by thymic epithelial cells	19
Foxp3⁺ regulatory T cells in the central nervous system and other nonlymphoid tissues	19
Zfp362 potentiates murine colonic inflammation by constraining Treg cell function rather than promoting Th17 cell differentiation	19
yEFIS 1^st Symposium: Shaping the future of Immunology in Europe, 10–11 November, 2022, Berlin, Germany	18
Front cover story: Eur. J. Immunol. 6'21	18

Back cover story: Eur. J. Immunol. 9'22	18
Journal roundup	18
Immunomodulatory activity of dipeptidyl peptidase‐4 inhibitors in immune‐related diseases	18
Transglutaminase 2 affinity and enzyme‐substrate intermediate stability as determining factors for T‐cell responses to gluten peptides in celiac disease	18
Guidelines for mouse and human DC functional assays	18
Immunomodulation under the lens of real‐time in vivo imaging	18
Constant regulation for stable CD8 T‐cell functional avidity and its possible implications for cancer immunotherapy	18
Young immunologists of Europe, unite ‐ and join us in Berlin!	18
Peptidylprolyl isomerase C (Ppic) regulates invariant Natural Killer T cell (iNKT) differentiation in mice	17
Activation and differentiation of cognate T cells by a dextran‐based antigen‐presenting system for cancer immunotherapy	16
A conserved pathway of transdifferentiation in murine Kupffer cells	16
Impressum	16
Metabolic dynamics instruct CD8⁺ T‐cell differentiation and functions	16
Issue Information: Eur. J. Immunol. 2'21	16
	16
Targeting Bcl6 in the TREX1 D18N murine model ameliorates autoimmunity by modulating T‐follicular helper cells and germinal center B cells	16
In This issue	16
COVID‐19 vaccines – common misperceptions, false claims and myths explained	16
Epithelial–immune cell interactions in allergic diseases	16
Med1 controls thymic T‐cell migration into lymph node through enhancer‐based Foxo1‐Klf2 transcription program	16
Issue Information: Eur. J. Immunol. 3'24	15
In memoriam Martin Röllinghoff (1941–2022)	15
Cover Story: Eur. J. Immunol. 2'24	15
Underrepresentation of activating KIR gene expression in single‐cell RNA‐seq data is due to KIR gene misassignment	15
Gingival fibroblast activation by Porphyromonas gingivalis is driven by TLR2 and is independent of the LPS‐TLR4 axis	15
B‐cell modulation with anti‐CD79b antibodies ameliorates experimental autoimmune encephalitis in mice	14
Site‐specific serology unveils cross‐reactive monoclonal antibodies targeting influenza A hemagglutinin epitopes	14
Comprehensive analysis of T‐cell receptor repertoires reveals antigen‐driven T‐cell clusters in patients with Behçet's syndrome	14
Induction of the sphingosine‐1‐phosphate signaling pathway by TGF‐β1 during Langerhans‐type dendritic cell differentiation	14
Renal medullary osmolytes NaCl and urea differentially modulate human tubular cell cytokine expression and monocyte recruitment	14
Regulatory T cells and transplantation tolerance: Emerging from the darkness?	14
UNC93B1 curbs cytosolic DNA signaling by promoting STING degradation	14
Monocytes promote UV‐induced epidermal carcinogenesis	14
Innate lymphoid cell characterization in the rat and their correlation to gut commensal microbes	14
Maturation signatures of conventional dendritic cell subtypes in COVID‐19 suggest direct viral sensing	14
Successful treatment of COVID‐19 infection with convalescent plasma in B‐cell‐depleted patients may promote cellular immunity	13
Cover Story: Eur. J. Immunol. 4'23	13
Longitudinal SARS‐CoV‐2 seroprevalence in Portugal and antibody maintenance 12 months after infection	13
Airway epithelial type‐2 alarmin profiles: Blood eosinophil counts remain in memory	13
Inhibition of tumor‐associated macrophages by trabectedin improves the antitumor adaptive immunity in response to anti‐PD‐1 therapy	13
Staphylococcus aureus‐derived factors promote human Th9 cell polarization and enhance a transcriptional program associated with allergic inflammation	13
Colostrum IgA1 antibodies recognize antigens from Helicobacter pylori and prevent cytoskeletal changes in human epithelial cells	12
Natural killer cell‐mediated ADCC in SARS‐CoV‐2‐infected individuals and vaccine recipients	12
Increased circulating T follicular helper 13 subset correlates with high IgE levels in pediatric allergic asthma	12
Polypyrimidine tract binding protein 1 regulates the activation of mouse CD8 T cells	12
Flow cytometry‐based high‐throughput RNAi screening for miRNAs regulating MHC class II HLA‐DR surface expression	12
Mechanisms of exTreg induction	12
Profiling the specificity of clonally expanded plasma cells during chronic viral infection by single‐cell analysis	12
A novel cryopreservation and biobanking strategy to study lymphoid tissue stromal cells in human disease	12
Ubiquitination network in the type I IFN‐induced antiviral signaling pathway	12
BAFF Blockade Attenuates B Cell MALT Formation in Conditional Nlrc5‐Deficient Mice With Helicobacter felis Infection	12
Issue Information: Eur. J. Immunol. 6'24	11
Dual Activation‐Induced Marker Combinations Efficiently Identify and Discern Antigen‐Specific and Bystander‐Activated Human CD4⁺ T Cells	11
Polymorphism in F pocket affects peptide selection and stability of type 1 diabetes‐associated HLA‐B39 allotypes	11
Non‐neutralizing antibodies protect against chronic LCMV infection by promoting infection of inflammatory monocytes in mice	11
Cover Story: Eur. J. Immunol. 7'24	11
Human Genetic GLUT1 Deficiency Results in Impaired T Cellular IFN‐γ Production	11
A fluorescent reporter model for the visualization and characterization of T_DC	11
IRF8 regulates efficacy of therapeutic anti‐CD20 monoclonal antibodies	11
	11
Colony morphotype governs innate and adaptive pulmonary immune responses to Mycobacterium abscessus infection in C3HeB/FeJ mice	11
Ubiquitin‐Conjugating Enzyme Ubc13 in Macrophages Suppresses Lung Tumor Progression Through Inhibiting PD‐L1 Expression	11
Fine needle aspiration of human lymph nodes reveals cell populations and soluble interactors pivotal to immunological priming	11
Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), 26–29 September, 2023, Strasbourg, France	11
Temporal associations of plasma levels of the secreted phospholipase A₂ family and mortality in severe COVID‐19	11
A pair of noncompeting neutralizing human monoclonal antibodies protecting from disease in a SARS‐CoV‐2 infection model	10
ILC1: Development, maturation, and transcriptional regulation	10
Issue Information: Eur. J. Immunol. 9'24	10
Immune signature of patients with cardiovascular disease predicts increased risk for a severe course of COVID‐19	10
The potential of γδ CAR and TRuC T cells: An unearthed treasure	10
Integrin activation enables rapid detection of functional Vδ1⁺ and Vδ2⁺ γδ T cells	10
	10
SARS‐CoV‐2 infection induces thymic atrophy mediated by IFN‐γ in hACE2 transgenic mice	10
Impressum	10
Bead‐by‐bead normalization of single antigen assays: A necessary step for accurate detection of weak anti‐HLA antibodies	10
Impact of antiretroviral therapy during primary HIV infection on T‐cell immunity after treatment interruption	10
Fluorochrome‐labeled inhibitors of caspase‐1 require membrane permeabilization to efficiently access caspase‐1 in macrophages	10
HLA‐DRB1*15:01 is a co‐receptor for Epstein–Barr virus, linking genetic and environmental risk factors for multiple sclerosis	10
T‐cell memory in tissues	10
A single subcutaneous or intranasal immunization with adenovirus‐based SARS‐CoV‐2 vaccine induces robust humoral and cellular immune responses in mice	10

Interferon α and β induce differential transcriptional and functional metabolic phenotypes in human macrophages and blunt glycolysis in response to antigenic stimuli	10
Characteristics and mechanisms of T‐cell senescence: A potential target for cancer immunotherapy	10
Atg16l2 augments Nlrc4 inflammasome activation by facilitating NAIPs–NLRC4 association	10
	10
Fate‐mapping studies in inbred mice: A model for understanding macrophage development and homeostasis?	10
Mast cells in type 2 skin inflammation: Maintenance and function	9
Four challenges to CAR T cells breaking the glass ceiling	9
P2X7 is expressed on human innate‐like T lymphocytes and mediates susceptibility to ATP‐induced cell death	9
Emerging roles of host and microbial bioactive lipids in inflammatory bowel diseases	9
6^th European Congress of Immunology, 1–4 September 2021, Virtual meeting	9
NLRP3 inflammasome triggers interleukin‐37 release from human monocytes	9
Mesenchymal stromal cells and their small extracellular vesicles in allergic diseases: From immunomodulation to therapy	9
Systemic lupus erythematosus patients contain B‐cell receptor repertoires sensitive to immunosuppressive drugs	9
Termination of CD40L co‐stimulation promotes human B cell differentiation into antibody‐secreting cells	9
Mesenchymal stromal cells‐derived small extracellular vesicles modulate DC function to suppress Th2 responses via IL‐10 in patients with allergic rhinitis	9
Adenovirus vector and mRNA vaccines: Mechanisms regulating their immunogenicity	9
Emerging imaging and liquid biomarkers in multiple sclerosis	9
The IFN‐inducible GTPase IRGB10 regulates viral replication and inflammasome activation during influenza A virus infection in mice	9
Ursodeoxycholic acid impairs liver‐infiltrating T‐cell chemotaxis through IFN‐γ and CX3CL1 production in primary biliary cholangitis	9
Assessing anti‐SARS‐CoV‐2 cellular immunity in 571 vaccines by using an IFN‐γ release assay	9
Regulatory T cells as a therapeutic approach for inflammatory bowel disease	9
Dimethyl itaconate selectively targets inflammatory and metabolic pathways in chronic lymphocytic leukemia	9
CD4⁺CD57⁺ senescent T cells as promoters of systemic lupus erythematosus pathogenesis and the therapeutic potential of senolytic BCL‐2 inhibitor	9
Diet, commensal microbiota‐derived extracellular vesicles, and host immunity	9
Distinct and dynamic activation profiles of circulating dendritic cells and monocytes in mild COVID‐19 and after yellow fever vaccination	9
T helper cell subsets: diversification of the field	9
The thioredoxin system: Balancing redox responses in immune cells and tumors	9
Measuring single‐cell protein secretion in immunology: Technologies, advances, and applications	9
Eosinophils interact with thymocytes and proliferate in the human thymus	9
Citrulline enteral administration markedly reduces immunosuppressive extrafollicular plasma cell differentiation in a preclinical model of sepsis	8
Pro‐ and antitumorigenic functions of γδ T cells	8
2024 German Society for Immunology Prizes	8
SARS‐CoV‐2 variants of concern elicit divergent early immune responses in hACE2 transgenic mice	8
Fully functional monocytic MDSC generation from the murine HoxB8 cell line	8
	8
Intrahepatic plasma cells, but not atypical memory B cells, associate with clinical phases of chronic hepatitis B	8
Follicular helper T cell signature of replicative exhaustion, apoptosis, and senescence in common variable immunodeficiency	8
Characterizing dynamic tumor–immune interactions in lung adenocarcinoma through orthotopic allograft modeling	8
TSLP and TSLPr Expression and Localization in the Airways of COPD and Non‐COPD Patients	8
Association of vaccine‐specific regulatory T cells with reduced antibody response to repeated influenza vaccination	8
Tolerogenic dendritic cells alleviate collagen‐induced arthritis by forming microchimerism and affecting the expression of immune checkpoint molecules	8
Cover Story: Eur. J. Immunol. 9'23	8
Probing TCR Specificity Using Artificial In Vivo Diversification of CDR3 Regions	8
French club of Young Immunologists: One year and counting	8
Rise of a CD27⁻ IgD⁻ CD11c⁺ B cells population in kidney recipients achieving long‐term graft stability under immunosuppression	8
	8
Cryopreservation of mouse thymus depletes thymocytes but supports immune reconstitution on transplantation	8
Levamisole suppresses activation and proliferation of human T cells by the induction of a p53‐dependent DNA damage response	8
Issue Information: Eur. J. Immunol. 8'23	7
Plasmodium vivax infection alters the peripheral immunoregulatory network of CD4 T follicular cells and B cells	7
Back cover story: Eur. J. Immunol. 6'21	7
Impressum	7
Intestinal tissue‐resident memory T cells maintain distinct identity from circulating memory T cells after in vitro restimulation	7
In this issue	7
	7
	7
Z‐nucleic acids: Uncovering the functions from past to present	7
Decoding the signaling profile of hematopoietic progenitor kinase 1 (HPK1) in innate immunity: A proteomic approach	7
Cover Story: Eur. J. Immunol. 6'23	7
Homologous and heterologous serological response to the N‐terminal domain of SARS‐CoV‐2 in humans and mice	7
Driving T cells to human atherosclerotic plaques: CCL3/CCR5 and CX3CL1/CX3CR1 migration axes	7
Decoding the potential role of regulatory T cells in sepsis‐induced immunosuppression	7
E‐Cadherin restricts mast cell degranulation in mice	7
Keratinocytes in the pathogenesis, phenotypic switch, and relapse of psoriasis	7
SARS‐CoV‐2‐reactive T‐cell receptors isolated from convalescent COVID‐19 patients confer potent T‐cell effector function	7
COVID‐19 rapidly increases MDSCs and prolongs innate immune dysfunctions	7
The Young Immunologists' Podcast: Immunology and Much More	7
A multifunctional mouse model to study the role of Samd3	7
MALT1 protease function in regulatory T cells induces MYC activity to promote mitochondrial function and cellular expansion	7
Correction	7
Vaccinia virus F1L blocks the ribotoxic stress response to subvert ZAKα‐dependent NLRP1 inflammasome activation	7
Transcriptional signatures associated with rubella virus‐specific humoral immunity after a third dose of MMR vaccine in women of childbearing age	7
Issue Information: Eur. J. Immunol. 3'23	6
Issue Information: Eur. J. Immunol. 5'21	6
Hobit and Blimp‐1 instruct the differentiation of iNKT cells into resident‐phenotype lymphocytes after lineage commitment	6
	6
In this issue	6
Miodrag L. Lukic (1941–2023)	6
In this issue	6
	6
	6
Issue Information: Eur. J. Immunol. 7'21	6
Towards prevention of autoimmune diseases: The example of rheumatoid arthritis	6
Contents: Eur. J. Immunol. 12'22	6
In this issue	6
Immunological analysis of the murine anti‐CD3‐induced cytokine release syndrome model and therapeutic efficacy of anti‐cytokine antibodies	6
Impressum	6
Current research and unmet needs in allergy and immunology in Germany: report presented by the DGfI and DGAKI task force Allergy & Immunology	6
Impressum	6
Issue Information: Eur. J. Immunol. 8'21	6
In this issue	6
	6
Front cover story: Eur. J. Immunol. 5'22	6
Antigen clearance at the peak of the primary immune response induces experimental autoimmune encephalomyelitis	6
Organizing the 16th Spring School on Immunology during a pandemic	6