European Journal of Clinical Investigation

Article	Citations
	141
Issue Information	86
Issue Information	73
Human blood metabolites and risk of severe COVID‐19: A Mendelian randomization study	65
Progress and challenges in the symbiosis of AI with science and medicine	60
Clinical outcomes and phylogenetic analysis in reflection with three predominant clades of SARS‐CoV‐2 variants	54
Correction to ‘Association Between Exposure to Air Pollution and Blood Lipids in the General Population of Spain’	52
Clinical implications of vascular dysfunction in acute and convalescent COVID‐19: A systematic review	51
Elevated factor XIa as a modulator of plasma fibrin clot properties in coronary artery disease	48
Effects of pharmacological inhibition of hyaluronic acid synthesis on experimental endometriosis	46
Impact of sirolimus on long‐term adverse cardiovascular outcomes in kidney transplant recipients: A nationwide cohort study	44
Issue Information	43
Impact of Anaemia on Management and Outcomes in Patients With Atrial Fibrillation: Insights From European and Asian Cohorts	41
Social determinants of health and cardiovascular outcomes in patients with heart failure	41
Glucagon and glucagon‐like peptide‐1 dual agonist therapy: A possible future towards fatty kidney disease	41
Role of PERK‐mediated pathway in the effect of mild hypothermia after cerebral ischaemia/reperfusion	41
Seasonal vitamin D levels and lupus low disease activity state in systemic lupus erythematosus	41
Adipocyte maturation impacts daunorubicin disposition and metabolism	38
Combination therapy with an SGLT‐2 inhibitor and finerenone in DKD: Are we there yet?	37
ACKR3 agonism induces heterodimerization with chemokine receptor CXCR4 and attenuates platelet function	37
Practical considerations for the use of vericiguat in older patients with heart failure and reduced ejection fraction	37
The use of the Crohn's disease exclusion diet (CDED) in adults with Crohn's disease: A randomized controlled trial	34
Does hospitalisation improve oral anticoagulant optimisation in patients with atrial fibrillation?	33
Blood pressure measurement for prediction of chronic pressure overload and cardiovascular events	33
Effects of glucagon‐like PEPTIDE‐1 receptor agonists on incidence of hepatocellular carcinoma and liver decompensation in patients with diabetes: A systematic review and META‐analysis	33

Comparison between thoracic ultrasound and chest x‐ray in detection of non‐infective early complications of cardiac implantable electronic devices implantation ( CRUSADERS	32
The hinge‐1 domain of Flna is not necessary for diverse physiological functions in mice	32
Automatic reorientation algorithm for myocardial perfusion SPECT using segmentation	32
Angiopoietin‐like protein 2 and mortality in patients with heart failure—Results from an observational study	31
Short‐ and long‐term risk stratification in acutely ill medical patients by implementing ankle‐brachial index and pulse wave velocity in the emergency setting	31
The glucagon‐like peptide‐1 receptor agonist semaglutide in diabetic kidney disease: A new kid on the block to afford maximal kidney protection	30
Hyperventilation testing in the diagnosis of vasospastic angina: A clinical review and meta‐analysis	29
Prognostic significance of echocardiographic deformation imaging in adult congenital heart disease	29
Incretin system and glucagon secretion in patients with chronic pancreatitis	29
MyofAPPcial: Construct validity of a novel technological aid for improving clinical reasoning in the management of myofascial pain syndrome	28
Mental stress as a trigger of cardiovascular events: A narrative review	28
Deep brain stimulation of fornix in Alzheimer's disease: From basic research to clinical practice	26
Concerns regarding interpretation in systematic review of exercise and endothelial glycocalyx	26
Cardiac proteomic profiling suggests that hypertrophic and dilated cardiomyopathy share a common pathogenetic pathway of the calcium signalling pathway	26
Mineralocorticoid receptor antagonists in kidney transplantation	25
A Comprehensive Meta‐Analysis of Bioadaptor Versus Drug‐Eluting Stents in Randomised Trials With Exploratory Single‐Arm Landmark Analyses	25
Refining the role of presurgical PET/4D‐CT in a large series of patients with primary hyperparathyroidism undergoing [18F]Fluorocholine PET/CT	25
ALKBH1 contributes to renal cell carcinoma progression by reducing N6‐methyladenine of GPR137	25
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A precise review on NAATs‐based diagnostic assays for COVID‐19: A motion in fast POC molecular tests	24
Carcinoembryonic antigen‐related cell adhesion molecule 1 in cancer: Blessing or curse?	24
The urotensin‐II receptor: A marker for staging and steroid outcome prediction in ulcerative colitis	23
Issue Information	23
Cardiovascular benefits of early rhythm control and healthy lifestyle in young atrial fibrillation	23
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Osteopontin is associated with neutrophil extracellular trap formation in elderly patients with severe sepsis	22
The potential of artificial intelligence in clinical trials	22
The ABCG8 polymorphism increases the risk of gallbladder cancer in the general population and gallstones in obese patients from Poland	22
Associations of 50 modifiable risk factors with atrial fibrillation using Mendelian randomization analysis	22
No evidence linking sleep traits with white blood cell counts: Multivariable‐adjusted and Mendelian randomization analyses	22
Harnessing controlled human infection models to accelerate vaccine development for neglected tropical diseases: Lessons from leishmaniasis	22
Differential utility of various frailty diagnostic tools in non‐geriatric hospital departments of several countries: A longitudinal study	22
Age‐related differences in cardiogenic shock secondary to Takotsubo syndrome	22
Constructive and obsessive criticism in science	21
Temporal trends of gender disparities in oral anticoagulant use in patients with atrial fibrillation	21
ELOVL2‐methylation and renal and cardiovascular event in patients with chronic kidney disease	21
Coronary artery calcium score and its association with stroke: A systematic review and meta‐analysis	21
The sodium–chloride difference: A marker of prognosis in patients with acute myocardial infarction	21
The influence of hypoxia‐mediated CEACAM6 upregulation on epithelial cell and macrophage response in the context of gastric cancer	20
Percutaneous coronary revascularization versus medical therapy in chronic coronary syndromes: An updated meta‐analysis of randomized controlled trials	20
Type 2 diabetes and chronic kidney disease as long‐term predictors of cardiovascular events in patients with coronary artery disease	20
Elevated factor XI is associated with recurrent left ventricular thrombus of unknown origin	20
The role of mean platelet volume in metabolic dysfunction associated steatotic liver disease	19
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Increased epicardial nerves and decreased intramyocardial PVAT in acute myocardial infarction	19
Targeting the SPHK1/S1P/S1PR2 axis ameliorates GH‐secreted pituitary adenoma progression	19
Systemic Inflammation and Risk of Thromboembolism, Mortality, and Treatment Response in Patients With Cancer Receiving Immune Checkpoint Inhibitors	19
Issue Information	19
Serum fibulin‐1 levels and target organ damage in patients at high cardiovascular risk: A prospective observational study	19
Role of the electrocardiogram in differentiating genetically determined dilated cardiomyopathy from athlete's heart	19

Nutrition, cognition and chronic kidney disease: A comprehensive review of interactions and interventions	19
Focal high‐intensity focused ultrasound therapy for localized prostate cancer: An interim analysis of the multinational FASST study	19
Circulating haematopoietic stem cells and long‐term outcomes of COVID‐19	19
PD‐L1 expression pattern as predictive factor of biological behaviour in intracranial meningiomas: A single‐center retrospective study	18
Cystatin C‐estimated GFR correlates with endothelial function improvements following bariatric surgery	18
Mortality after transvenous lead extraction: A risk prediction model for sustainable care delivery	18
Impact of stroke history on procedural cerebrovascular insult probability and long‐term outcome after TAVI	18
Artificial‐intelligence‐based decision support tools for the differential diagnosis of colitis	18
The effect of subcutaneous dulaglutide on weight loss in patients with Type 2 diabetes mellitus: Systematic review and meta‐analysis of randomized controlled trials	18
Novel cutting edge nano‐strategies to address old long‐standing complications in cardiovascular diseases. A comprehensive review	17
A systematic review and meta‐analysis on oncological radiotherapy in patients with a cardiac implantable electronic device: Prevalence and predictors of device malfunction in 3121 patients	17
Statin treatment reduces protein carbonylation in patients with COPD: A randomized controlled study	17
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Residual risk prediction in anticoagulated patients with atrial fibrillation using machine learning: A report from the GLORIA‐AF registry phase II/III	17
Hypercholesterolemia and inflammation—Cooperative cardiovascular risk factors	17
Artificial intelligence evaluation of coronary computed tomography angiography for coronary stenosis classification and diagnosis	17
Association between the use of lipid‐lowering drugs and the risk of inflammatory bowel disease	17
The role of artificial intelligence in cardiovascular research: Fear less and live bolder	16
Pulse Wave Velocity, Mortality and Cardiovascular Disease in Chronic Kidney Disease: A Systematic Review and Meta‐Analysis	16
Psychiatric disorders and Type 2 diabetes mellitus: A bidirectional Mendelian randomization	16
Changing trends in the prevalence of heart failure impairment with Thalassemias over three decades	16
The association between the basal metabolic rate and cardiovascular disease: A two‐sample Mendelian randomization study	16
Fatigue and itch severity in patients with PBC and PSC: Prospective analysis of two large cohorts	16
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Association between CMR‐derived hepatic T1‐time, tricuspid regurgitation and survival	15
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Iron‐related intercellular communication in the liver: Main players and mechanisms	15
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Synovial expression of glucocorticoid receptor parallels fibroblast activation in patients with rheumatoid arthritis	15
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Sentinel lymph node biopsy for breast cancer during pregnancy: A comprehensive update	14
In‐house editorials and journalistic pieces comprise a massive corpus in the scientific literature that can be improved	14
Liver disease in management and outcomes of European and Asian patients with atrial fibrillation: A report from two observational prospective registries	14
Respiratory dysfunction in old mice could be related to inflammation and lung fibrosis induced by hyperphosphatemia	14
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Membrane oxygenator longevity was higher in argatroban‐treated patients undergoing vvECMO	14
Reciprocity between the regulation of the expression and functions of CEACAM	14
When less is more: The association between the expression of polymorphic CYPs and AFB1‐induced HCC	14
Albumin, urea‐to‐albumin ratio, or the albumin‐to‐creatinine ratio to predict outcomes in heart failure with mildly reduced ejection fraction	14
Burden of hypertensive heart disease and its attributable risk factors in 204 countries and territories, 1990–2021: Results from the global burden of disease study 2021	13
Total lesion glycolysis is a promising predictor of chemo‐response in pancreatic cancer patients treated with neoadjuvant chemotherapy prior to surgery	13
Clinical outcomes of transcatheter edge‐to‐edge repair in patients with functional mitral regurgitation and pulmonary hypertension	13
Issue Information	13
Advanced biomedical imaging for accurate discrimination and prognostication of mediastinal masses	13
Six‐minute walking distance and desaturation–distance ratio in allogeneic stem cell transplantation	13
Protective effects of avasopasem manganese (GC4419) against sepsis‐induced acute lung injury: A comprehensive experimental study	13
Issue Information	13
Long‐term risk of delayed postoperative Crohn's disease recurrence in patients with no or mild endoscopic recurrence at first assessment	13
Prehospital seizures: Short‐term outcomes and risk stratification based in point‐of‐care testing	13
Association of aortic stiffness early post myocardial infarction with left ventricular remodelling	13
HDL function and composition in atherothrombotic cardiovascular disease with very high HDL ‐C	13
Prognostic impact of abnormal sodium burden in heart failure patients with preserved ejection fraction	13
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Gender differences on healthcare accessibility and outcomes of a electronic inter‐clinician consultation program at the cardiology department in a Galician Health Area	12
Targeting nicotinamide N‐methyltransferase decreased aggressiveness of osteosarcoma cells	12
Triglyceride‐glycaemic index: Insights into predicting fetal macrosomia and its interaction with gestational diabetes mellitus: A cohort study of Chinese pregnant women	12
Anthropometric measures, predicted visceral adipose tissue and biomarkers of chronic inflammation	12
Novel 3D versus traditional transesophageal echocardiography techniques: Defining differences in the diagnosis of infective endocarditis	12
The autonomic nervous system and bone health in chronic kidney disease	12
Body composition markers are more strongly associated with type 2 diabetes than inflammatory markers—Results from the study of health in Pomerania	12
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Localization of accessory pathways in Wolff‐Parkinson‐white syndrome using ECG‐based multi‐task deep learning	12
Evidence base for yearly respiratory virus vaccines: Current status and proposed improved strategies	12
Preprocedural assessment of coronary artery disease in patients undergoing transcatheter aortic valve implantation: Rationale and design of the EASE‐IT CT registry	12
Sex disparities for patients with atrial fibrillation in the direct oral anticoagulant era	12
Decompressive surgery in cerebral venous thrombosis: A systematic review and meta‐analysis	12
Antihypertensive treatment changes and related clinical outcomes in older hospitalized patients	12
Adipose tissue metabolomics identifies disease stage and tumour invasiveness of rectal cancer	12
Clinical measures in chronic neuropathic pain are related to the Kennedy and endocannabinoid pathways	12
Impact of prior oral anticoagulation therapies on post‐discharge outcomes after COVID‐19: Results from a global federated health network analysis	12
Machine learning in cardiovascular risk assessment: Towards a precision medicine approach	12
Risk prediction of atrial fibrillation and its complications in the community using hs troponin I	12
Issue Information	12
Abstracts	11
Promising biomarker panel to monitor therapeutic efficacy of neoadjuvant chemotherapy in pancreatic cancer patients	11
Ramadan intermittent fasting reduces visceral fat and improves gastrointestinal motility	11
Assessing cardiorespiratory fitness relative to sex improves surgical risk stratification	11
Implications of inflammation and sex in lower extremity arterial disease	11

Extracellular matrix mechanical cues (dys)regulate metabolic redox homeostasis due to impaired autophagic flux	11
Abnormal circulating steroids refine risk of progression to heart failure in ischemic heart disease	11
Sotatercept in pulmonary hypertension and beyond	11
Increased body mass index is associated with sarcopenia and related outcomes	11
Ambulatory central BP and arterial stiffness in patients with and without intradialytic hypertension	11
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The influence of viral protein R amino acid substitutions on clinical outcomes in people living with HIV: A systematic review	10
Deep learning for electrocardiogram interpretation: Bench to bedside	10
Global, regional and national burden of alopecia areata and its associated diseases, 1990–2019: A systematic analysis of the Global Burden of Disease Study 2019	10
Issue Information	10
Subcutaneous Adipose Tissue as a Metabolic Mirror: Transcriptomic Insights Into Glycaemic Dysregulation	10
Global, regional and national burden of epilepsy in children and adolescents, 1990–2021: A systematic analysis for the Global Burden of Disease Study 2021	10
Patient‐reported outcomes in internal medicine: Methodological considerations for valid measurement and interpretation	10
The biology of lipoprotein(a): From genetics to molecular mechanisms	10
Risk of cardiovascular disease in elderly subjects with obesity and liver fibrosis and the potential benefit of statin treatment	10
Effects of NAD+ precursors on blood pressure, C‐reactive protein concentration and carotid intima‐media thickness: A meta‐analysis of randomized controlled trials	10
First‐line diagnostic tests to intercept primary heart involvement in systemic sclerosis: Clinical associations from the SPRING‐SIR registry	10
Cancer and cardiovascular diseases: A deadly combination	10
Depression in nonalcoholic fatty liver disease and all‐cause/cause‐specific mortality	10
LINC02605 involved in paediatric Mycoplasma pneumoniae pneumonia complicated with diarrhoea via miR‐539‐5p/CXCL1 axis	10
The definition of long COVID used in interventional studies	10
Heart failure in patients is associated with downregulation of mitochondrial quality control genes	10
Recent advances in multimodality imaging‐guided therapy in pericarditis	10
One‐hour post‐load glucose and subclinical left atrial myocardial dysfunction in hypertensive patients	10
Impact of oncologic diseases on outcome in patients with severe isolated tricuspid regurgitation	10
ESCI Newsletter	10
Meta‐analysis of factors associated with antidiabetic drug prescribing for type 2 diabetes mellitus	10
Establishing a Zebrafish Functional Assay to Assess the Pathogenicity of Variants of Uncertain Significance in Ciliopathies	10
Current investigation of carcinoembryonic antigen cell adhesion molecule (CEACAM) biology summary of the 32nd CEA symposium: 20–23 September 2024. Würzburg, Germany	9
Genetic evidence for the causal linkage between telomere length and aortic aneurysm risk: A Mendelian randomisation study	9
Zinc finger proteins and ATP‐binding cassette transporter‐dependent multidrug resistance	9
Sexual dimorphism in exercise‐induced response on steroid hormones to a 24‐week supervised concurrent training intervention	9
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A weekly 4‐methylpyrazole treatment attenuates the development of non‐obese metabolic dysfunction‐associated steatotic liver disease (MASLD) in male mice: Role of JNK	9
A Mendelian randomization study on causal effects of leisure sedentary behaviour on the risk of rheumatoid arthritis	9
miR‐619‐5p and cardiogenic shock in patients with ST‐segment elevation myocardial infarction	9
Issue Information	9
Liraglutide modulates morpho‐functional and inflammatory gastrointestinal responses in rats	9
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Familial hypercholesterolemia is related to cardiovascular disease, heart failure and atrial fibrillation. Results from a population‐based study	9
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The conservativeness of standard C statistics in the prediction of clinical events	8
Fatal attractions that trigger inflammation and drive atherosclerotic disease	8
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Educational level, clinical outcomes and quality of care in a Swiss cohort of patients with acute coronary syndromes	8
Comparison of high‐sensitive cardiac troponin T and I in patients with chronic coronary syndrome	8
Proprotein convertase subtilisin/kexin type 9 (PCSK9) and clinical outcomes in patients with end‐stage renal disease	8
Enhanced neutrophil extracellular traps formation in AF patients with dilated left atrium	8
Sex‐associated differences in cardiac ageing: Clinical aspects and molecular mechanisms	8
Erythrocyte membrane fluidity: A novel biomarker of residual cardiovascular risk in type 2 diabetes	8
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Transsulfuration and folate pathways in rheumatoid arthritis: A systematic review and meta‐analysis	8
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Self‐reported sleep characteristics and cardiovascular disease risk factors	8
Plasma lipoprotein(a) is associated with calcification activity of the thoracic aorta and aortic valve in statin naïve individuals with diabetes mellitus	8
Angiotensin converting enzyme 2 level and its significance in COVID‐19 and other diseases patients	8
Machine learning prediction of moderate‐to‐severe acute kidney injury after ICU admission and cardiac surgery with urine trace elements	8
Serological markers and long COVID—A rapid systematic review	8
The body mass index increases the genetic risk scores' ability to predict risk of hepatic damage in European adolescents: The HELENA study	8
Methodological and statistical considerations: Batch‐dependent adverse effects of COVID‐19 vaccines	8
Social isolation and loneliness: Undervalued risk factors for disease states and mortality	8
Central role of pro‐IGFII(68–88) (big IGFII) in the pathogenesis nonislet cell tumour‐induced hypoglycaemia	8
Corrigendum	8
Sex‐specific and hormone‐related differences in vascular remodelling in atherosclerosis	8