European Journal of Clinical Investigation

Article	Citations
Clinical outcomes and phylogenetic analysis in reflection with three predominant clades of SARS‐CoV‐2 variants	130
Hydrogen sulphide: Diabetic cardiomyopathy as the paradigm of its pleiotropic function	97
Role of PERK‐mediated pathway in the effect of mild hypothermia after cerebral ischaemia/reperfusion	80
Effects of pharmacological inhibition of hyaluronic acid synthesis on experimental endometriosis	78
New insights into Covid‐19 disease. Apo‐A1 antibodies are generated after mRNA Covid‐19 vaccination and after Covid‐19 infection	76
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Elevated factor XIa as a modulator of plasma fibrin clot properties in coronary artery disease	65
Seasonal vitamin D levels and lupus low disease activity state in systemic lupus erythematosus	46
The ‘new normality’ in research? What message are we conveying our medical students?	46
Glucagon and glucagon‐like peptide‐1 dual agonist therapy: A possible future towards fatty kidney disease	40
Adipocyte maturation impacts daunorubicin disposition and metabolism	39
Issue Information	38
Clinical predictors of late SARS‐CoV‐2 positivity in Italian internal medicine wards	36
Effects of glucagon‐like PEPTIDE‐1 receptor agonists on incidence of hepatocellular carcinoma and liver decompensation in patients with diabetes: A systematic review and META‐analysis	36
The use of the Crohn's disease exclusion diet (CDED) in adults with Crohn's disease: A randomized controlled trial	36
Combination therapy with an SGLT‐2 inhibitor and finerenone in DKD: Are we there yet?	34
Progress and challenges in the symbiosis of AI with science and medicine	34
Angiotensin‐converting enzyme 2 and transmembrane protease serine 2 in female and male patients with end‐stage kidney disease	33
rFVIII‐Fc in severe haemophilia A: The incentive switch in case of high risk of joint bleedings	33
Impact of sirolimus on long‐term adverse cardiovascular outcomes in kidney transplant recipients: A nationwide cohort study	32
Prehospital troponin as a predictor of early clinical deterioration	30
Acetyl‐CoA‐driven respiration in frozen muscle contributes to the diagnosis of mitochondrial disease	30
Does hospitalisation improve oral anticoagulant optimisation in patients with atrial fibrillation?	29
ACKR3 agonism induces heterodimerization with chemokine receptor CXCR4 and attenuates platelet function	29
Circ_0021087 acts as a miR‐184 sponge and represses gastric cancer progression by adsorbing miR‐184 and elevating FOSB expression	29

Human blood metabolites and risk of severe COVID‐19: A Mendelian randomization study	28
Social determinants of health and cardiovascular outcomes in patients with heart failure	28
Correction to ‘Association Between Exposure to Air Pollution and Blood Lipids in the General Population of Spain’	28
Omega‐3 phospholipids and obesity‐associated NAFLD: Potential mechanisms and therapeutic perspectives	27
Clinical implications of vascular dysfunction in acute and convalescent COVID‐19: A systematic review	27
The role of vascular smooth muscle cells in the development of aortic aneurysms and dissections	26
Clinical use of controlled oxygenated rewarming of kidney grafts prior to transplantation by ex vivo machine perfusion. A pilot study	26
Issue Information	25
Carcinoembryonic antigen‐related cell adhesion molecule 1 in cancer: Blessing or curse?	25
Automatic reorientation algorithm for myocardial perfusion SPECT using segmentation	23
Concerns regarding interpretation in systematic review of exercise and endothelial glycocalyx	23
Impaired fibrin clot lysis is associated with increased mortality in patients after coronary artery bypass grafting: A long‐term follow‐up study	23
A precise review on NAATs‐based diagnostic assays for COVID‐19: A motion in fast POC molecular tests	23
Cardiac proteomic profiling suggests that hypertrophic and dilated cardiomyopathy share a common pathogenetic pathway of the calcium signalling pathway	23
Markedly elevated serum preoperative thyroglobulin predicts radioiodine‐refractory thyroid cancer	23
Blood pressure measurement for prediction of chronic pressure overload and cardiovascular events	23
BNT162b2 Vaccine‐Associated Myo/Pericarditis in Adolescents: A Stratified Risk‐Benefit Analysis	22
Short‐ and long‐term risk stratification in acutely ill medical patients by implementing ankle‐brachial index and pulse wave velocity in the emergency setting	22
The hinge‐1 domain of Flna is not necessary for diverse physiological functions in mice	22
Prognostic significance of echocardiographic deformation imaging in adult congenital heart disease	22
ALKBH1 contributes to renal cell carcinoma progression by reducing N6‐methyladenine of GPR137	22
Refining the role of presurgical PET/4D‐CT in a large series of patients with primary hyperparathyroidism undergoing [18F]Fluorocholine PET/CT	22
Mineralocorticoid receptor antagonists in kidney transplantation	22
Adipose tissue insulin resistance and lipidome alterations as the characterizing factors of non‐alcoholic steatohepatitis	22
Hyperventilation testing in the diagnosis of vasospastic angina: A clinical review and meta‐analysis	21
Deep brain stimulation of fornix in Alzheimer's disease: From basic research to clinical practice	20
CONVALESCENT plasma for COVID‐19: A meta‐analysis of clinical trials and real‐world evidence	20
MyofAPPcial: Construct validity of a novel technological aid for improving clinical reasoning in the management of myofascial pain syndrome	20
The glucagon‐like peptide‐1 receptor agonist semaglutide in diabetic kidney disease: A new kid on the block to afford maximal kidney protection	20
Mushrooms on the plate: Trends towards NAFLD treatment, health improvement and sustainable diets	20
Constructive and obsessive criticism in science	19
Noncommunicable diseases, climate change and iniquities: What COVID‐19 has taught us about syndemic	18
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Developmental programming and ageing of male reproductive function	18
Issue Information	18
Percutaneous coronary revascularization versus medical therapy in chronic coronary syndromes: An updated meta‐analysis of randomized controlled trials	18
Focal high‐intensity focused ultrasound therapy for localized prostate cancer: An interim analysis of the multinational FASST study	17
Off‐label underdosing of four individual NOACs in patients with nonvalvular atrial fibrillation: A systematic review and meta‐analysis of observational studies	17
The urotensin‐II receptor: A marker for staging and steroid outcome prediction in ulcerative colitis	17
Nutrition, cognition and chronic kidney disease: A comprehensive review of interactions and interventions	17
Differential utility of various frailty diagnostic tools in non‐geriatric hospital departments of several countries: A longitudinal study	17
Hydrogen sulphide in liver glucose/lipid metabolism and non‐alcoholic fatty liver disease	17
Cognitive impairment and endothelial dysfunction in convalescent COVID‐19 patients undergoing rehabilitation	17
ELOVL2‐methylation and renal and cardiovascular event in patients with chronic kidney disease	17
Coronary artery calcium score and its association with stroke: A systematic review and meta‐analysis	17
Clinical prediction of genotypes in hypertrophic cardiomyopathy: A systematic review	16
No evidence linking sleep traits with white blood cell counts: Multivariable‐adjusted and Mendelian randomization analyses	16
Obesity paradox in patients with chronic total occlusion of coronary artery	16
Temporal trends of gender disparities in oral anticoagulant use in patients with atrial fibrillation	16
What determines health professionals’ COVID‐19 vaccine hesitancy? A nationwide study	16

The ABCG8 polymorphism increases the risk of gallbladder cancer in the general population and gallstones in obese patients from Poland	16
Omega‐3 fatty acids in adipose tissue and risk of atrial fibrillation	16
Associations of 50 modifiable risk factors with atrial fibrillation using Mendelian randomization analysis	16
The influence of hypoxia‐mediated CEACAM6 upregulation on epithelial cell and macrophage response in the context of gastric cancer	16
Issue Information	16
Elevated factor XI is associated with recurrent left ventricular thrombus of unknown origin	15
Issue Information	15
Impact of stroke history on procedural cerebrovascular insult probability and long‐term outcome after TAVI	15
Type 2 diabetes and chronic kidney disease as long‐term predictors of cardiovascular events in patients with coronary artery disease	15
Cardiovascular benefits of early rhythm control and healthy lifestyle in young atrial fibrillation	15
Nomogram for stratifying patients with lifelong premature ejaculation before using the PHQ‐9: An observational study	15
The sodium–chloride difference: A marker of prognosis in patients with acute myocardial infarction	15
Osteopontin is associated with neutrophil extracellular trap formation in elderly patients with severe sepsis	15
The triglyceride‐glucose index as an adiposity marker and a predictor of fat loss induced by a low‐calorie diet	15
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Increased epicardial nerves and decreased intramyocardial PVAT in acute myocardial infarction	14
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Haemodynamic impact of MitraClip in patients with functional mitral regurgitation and pulmonary hypertension	14
Synovial expression of glucocorticoid receptor parallels fibroblast activation in patients with rheumatoid arthritis	14
Circulating haematopoietic stem cells and long‐term outcomes of COVID‐19	14
A systematic review and meta‐analysis on oncological radiotherapy in patients with a cardiac implantable electronic device: Prevalence and predictors of device malfunction in 3121 patients	14
Mortality after transvenous lead extraction: A risk prediction model for sustainable care delivery	14
Author index	14
Association between the use of lipid‐lowering drugs and the risk of inflammatory bowel disease	13
The association between the basal metabolic rate and cardiovascular disease: A two‐sample Mendelian randomization study	13
The role of artificial intelligence in cardiovascular research: Fear less and live bolder	13
Open Access Publications is our mission in 2022: perspective from the editors of the European Journal of Clinical Investigation	13
Risk of gonadotoxicity with immunotherapy and targeted agents remains an unsolved but crucial issue	13
Fatigue and itch severity in patients with PBC and PSC: Prospective analysis of two large cohorts	13
Serum fibulin‐1 levels and target organ damage in patients at high cardiovascular risk: A prospective observational study	13
Changing trends in the prevalence of heart failure impairment with Thalassemias over three decades	13
Role of the electrocardiogram in differentiating genetically determined dilated cardiomyopathy from athlete's heart	13
Residual risk prediction in anticoagulated patients with atrial fibrillation using machine learning: A report from the GLORIA‐AF registry phase II/III	13
Cystatin C‐estimated GFR correlates with endothelial function improvements following bariatric surgery	12
Targeting the SPHK1/S1P/S1PR2 axis ameliorates GH‐secreted pituitary adenoma progression	12
Hypercholesterolemia and inflammation—Cooperative cardiovascular risk factors	12
The skin microbiome of infected pressure ulcers: A review and implications for health professionals	12
Artificial‐intelligence‐based decision support tools for the differential diagnosis of colitis	12
Is there an ‘ideal’ diet for patients with NAFLD?	12
Statin treatment reduces protein carbonylation in patients with COPD: A randomized controlled study	12
Novel cutting edge nano‐strategies to address old long‐standing complications in cardiovascular diseases. A comprehensive review	12
Artificial intelligence evaluation of coronary computed tomography angiography for coronary stenosis classification and diagnosis	12
Psychiatric disorders and Type 2 diabetes mellitus: A bidirectional Mendelian randomization	12
The effect of subcutaneous dulaglutide on weight loss in patients with Type 2 diabetes mellitus: Systematic review and meta‐analysis of randomized controlled trials	12
Respiratory dysfunction in old mice could be related to inflammation and lung fibrosis induced by hyperphosphatemia	11
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Reciprocity between the regulation of the expression and functions of CEACAM	11
Prognostic impact of abnormal sodium burden in heart failure patients with preserved ejection fraction	11
Sentinel lymph node biopsy for breast cancer during pregnancy: A comprehensive update	11
Advanced biomedical imaging for accurate discrimination and prognostication of mediastinal masses	11
Membrane oxygenator longevity was higher in argatroban‐treated patients undergoing vvECMO	11
Similarities between fibroblasts and cardiomyocytes in the study of the permeability transition pore	11
List of Reviewers	11
Discriminatory capacity of obesity indicators as predictors of high liver fat in US adolescents	11
Issue Information	11
Fatty kidney: A possible future for chronic kidney disease research	11
Issue Information	11
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Issue Information	11
Antithrombotic therapy and clinical outcomes at 1 year in the Spanish cohort of the EORP‐AF Long‐term General Registry	11
Heart, kidney and left ventricular assist device: a complex trio	11
When less is more: The association between the expression of polymorphic CYPs and AFB1‐induced HCC	11
Shorter periconception maternal telomere length and the risk of congenital cardiac outflow defects in the offspring	11
Impact of prior oral anticoagulation therapies on post‐discharge outcomes after COVID‐19: Results from a global federated health network analysis	11
Machine learning in cardiovascular risk assessment: Towards a precision medicine approach	10
Total lesion glycolysis is a promising predictor of chemo‐response in pancreatic cancer patients treated with neoadjuvant chemotherapy prior to surgery	10
Six‐minute walking distance and desaturation–distance ratio in allogeneic stem cell transplantation	10
Clinical measures in chronic neuropathic pain are related to the Kennedy and endocannabinoid pathways	10
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Long‐term risk of delayed postoperative Crohn's disease recurrence in patients with no or mild endoscopic recurrence at first assessment	10
The role of microbiota in nonalcoholic fatty liver disease	10
Localization of accessory pathways in Wolff‐Parkinson‐white syndrome using ECG‐based multi‐task deep learning	10
CHA2DS2‐VASc impact on risk following percutaneous coronary intervention in atrial fibrillation	10
Anthropometric measures, predicted visceral adipose tissue and biomarkers of chronic inflammation	10
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Issue Information	10
Abstract	10
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Issue Information	10
Evidence base for yearly respiratory virus vaccines: Current status and proposed improved strategies	10

Association of aortic stiffness early post myocardial infarction with left ventricular remodelling	10
Circulation tumour DNA in predicting recurrence and prognosis in operable colorectal cancer patients: A meta‐analysis	10
Issue Information	10
Prehospital seizures: Short‐term outcomes and risk stratification based in point‐of‐care testing	10
Targeting nicotinamide N‐methyltransferase decreased aggressiveness of osteosarcoma cells	10
Triglyceride‐glycaemic index: Insights into predicting fetal macrosomia and its interaction with gestational diabetes mellitus: A cohort study of Chinese pregnant women	9
Novel 3D versus traditional transesophageal echocardiography techniques: Defining differences in the diagnosis of infective endocarditis	9
The autonomic nervous system and bone health in chronic kidney disease	9
Antihypertensive treatment changes and related clinical outcomes in older hospitalized patients	9
Poor self‐reported sleep is associated with risk factors for cardiovascular disease: A cross‐sectional analysis in half a million adults	9
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Adrenocortical dysfunction in rheumatoid arthritis: Α narrative review and future directions	9
Promising biomarker panel to monitor therapeutic efficacy of neoadjuvant chemotherapy in pancreatic cancer patients	9
Body composition markers are more strongly associated with type 2 diabetes than inflammatory markers—Results from the study of health in Pomerania	9
56th Annual Scientific Meeting, 8–10 June 2022, Bari, Italy, “Promoting Biomedical Research, Equal Health and Environment in the post‐COVID Syndemic Era”	9
Ambulatory central BP and arterial stiffness in patients with and without intradialytic hypertension	9
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Decompressive surgery in cerebral venous thrombosis: A systematic review and meta‐analysis	9
Risk prediction of atrial fibrillation and its complications in the community using hs troponin I	9
Increased body mass index is associated with sarcopenia and related outcomes	9
Issue Information	9
Influenza vaccination in cancer patients receiving immune checkpoint inhibitors: A systematic review	9
Abnormal circulating steroids refine risk of progression to heart failure in ischemic heart disease	9
Sex disparities for patients with atrial fibrillation in the direct oral anticoagulant era	9
Issue Information	9
Ramadan intermittent fasting reduces visceral fat and improves gastrointestinal motility	9
Gender differences on healthcare accessibility and outcomes of a electronic inter‐clinician consultation program at the cardiology department in a Galician Health Area	9
Microvascular disease increases the risk of lower limb amputation – A Western Danish cohort study	9
Science and the social media: Time for a reset	9
Preprocedural assessment of coronary artery disease in patients undergoing transcatheter aortic valve implantation: Rationale and design of the EASE‐IT CT registry	9
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LINC02605 involved in paediatric Mycoplasma pneumoniae pneumonia complicated with diarrhoea via miR‐539‐5p/CXCL1 axis	8
Isoprostane‐8 and GDF‐15 as novel markers of post‐PE syndrome: Relation with prothrombotic factors	8
Low triiodothyronine syndrome is associated with stroke‐associated pneumonia	8
Distant metastasis and prognostic factors in patients with invasive ductal carcinoma of the breast	8
Impact of oncologic diseases on outcome in patients with severe isolated tricuspid regurgitation	8
The influence of viral protein R amino acid substitutions on clinical outcomes in people living with HIV: A systematic review	8
Effects of NAD+ precursors on blood pressure, C‐reactive protein concentration and carotid intima‐media thickness: A meta‐analysis of randomized controlled trials	8
Common misconceptions of randomized controlled trials in oncology	8
ESCI Newsletter	8
Quality of life assessment in amyloid transthyretin (ATTR) amyloidosis	8
Depression in nonalcoholic fatty liver disease and all‐cause/cause‐specific mortality	8
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Sotatercept in pulmonary hypertension and beyond	8
Use of rivaroxaban attenuates renal function impairment in patients with atrial fibrillation: insights of the EMIR study	8
Assessing cardiorespiratory fitness relative to sex improves surgical risk stratification	8
Issue Information	8
Global, regional and national burden of alopecia areata and its associated diseases, 1990–2019: A systematic analysis of the Global Burden of Disease Study 2019	8
Risk of cardiovascular disease in elderly subjects with obesity and liver fibrosis and the potential benefit of statin treatment	8
Extracellular matrix mechanical cues (dys)regulate metabolic redox homeostasis due to impaired autophagic flux	8
One‐hour post‐load glucose and subclinical left atrial myocardial dysfunction in hypertensive patients	8
Cancer and cardiovascular diseases: A deadly combination	7
Heart failure in patients is associated with downregulation of mitochondrial quality control genes	7
Liraglutide modulates morpho‐functional and inflammatory gastrointestinal responses in rats	7
Serological markers and long COVID—A rapid systematic review	7
Frailty trajectories in community‐dwelling older adults during COVID‐19 pandemic: The PRESTIGE study	7
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The definition of long COVID used in interventional studies	7
Issue Information	7
Sexual dimorphism in exercise‐induced response on steroid hormones to a 24‐week supervised concurrent training intervention	7
Plasma lipoprotein(a) is associated with calcification activity of the thoracic aorta and aortic valve in statin naïve individuals with diabetes mellitus	7
An online nomogram of acute respiratory distress syndrome originating from pulmonary disease	7
Deep learning for electrocardiogram interpretation: Bench to bedside	7
Meta‐analysis of factors associated with antidiabetic drug prescribing for type 2 diabetes mellitus	7
Angiotensin converting enzyme 2 level and its significance in COVID‐19 and other diseases patients	7
Sex‐associated differences in cardiac ageing: Clinical aspects and molecular mechanisms	7
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Genetic evidence for the causal linkage between telomere length and aortic aneurysm risk: A Mendelian randomisation study	7
Interatrial block, atrial fibrillation, and thrombotic events in COVID‐19	6
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Yield of bone scintigraphy screening for transthyretin‐related cardiac amyloidosis in different conditions: Methodological issues and clinical implications	6
Major bleeding in patients with pulmonary embolism presenting with syncope	6
Corrigendum	6
miR‐619‐5p and cardiogenic shock in patients with ST‐segment elevation myocardial infarction	6
‘Obesities’: Position statement on a complex disease entity with multifaceted drivers	6
Self‐reported sleep characteristics and cardiovascular disease risk factors	6
Redox profiles of amyotrophic lateral sclerosis lymphoblasts with or without known SOD1 mutations	6
Mesenchymal stem cells for lysosomal storage and polyglutamine disorders: Possible shared mechanisms	6
Right ventricle dysfunction assessment for transcatheter tricuspid valve repair: A matter of debate	6
Zinc finger proteins and ATP‐binding cassette transporter‐dependent multidrug resistance	6
A weekly 4‐methylpyrazole treatment attenuates the development of non‐obese metabolic dysfunction‐associated steatotic liver disease (MASLD) in male mice: Role of JNK	6
Issue Information	6
A Mendelian randomization study on causal effects of leisure sedentary behaviour on the risk of rheumatoid arthritis	6
Enoxaparin for thromboprophylaxis in hospitalized COVID‐19 patients: The X‐COVID‐19 Randomized Trial	6
A systematic review of the correlation between serum asymmetric dimethylarginine, carotid atherosclerosis and ischaemic stroke	6
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Infectious mononucleosis is associated with an increased incidence of NAFLD	6
Effects of vegetarian versus Mediterranean diet on kidney function: Findings from the CARDIVEG study	6
Issue Information	6
Current investigation of carcinoembryonic antigen cell adhesion molecule (CEACAM) biology summary of the 32nd CEA symposium: 20–23 September 2024. Würzburg, Germany	6
Building a competitive infrastructure to support clinical research in healthcare institution	6
Familial hypercholesterolemia is related to cardiovascular disease, heart failure and atrial fibrillation. Results from a population‐based study	6
Comparison of high‐sensitive cardiac troponin T and I in patients with chronic coronary syndrome	6
Issue Information	6
Cardiac and renal outcomes of direct oral anticoagulants in patients with atrial fibrillation	6