Drugs

Papers
(The median citation count of Drugs is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)
ArticleCitations
Correction: Targeting KRASG12C in Non-Small-Cell Lung Cancer: Current Standards and Developments471
Correction: New Pharmacologic Approaches to the Treatment of Bipolar Depression407
Suprachoroidal Space Triamcinolone Acetonide: A Review in Uveitic Macular Edema245
Targeting DNA Damage Response Deficiency in Thoracic Cancers216
New Therapies on the Horizon for Primary Biliary Cholangitis213
Clinical Efficacy, Safety and Imaging Effects of Oral Valiltramiprosate in APOEε4/ε4 Homozygotes with Early Alzheimer’s Disease: Results of the Phase III, Randomized, Double-Blind, Placebo-Controlled,197
Eftrenonacog Alfa: A Review in Haemophilia B189
Comment on “Recent Human Papillomavirus Vaccination is Associated with a Lower Risk of COVID-19: A US Database Cohort Study”162
Aztreonam-Avibactam: A Review in the Treatment of Serious Bacterial Infections Caused by Aerobic Gram-Negative Organisms151
Authors’ Reply to Toda: Multimodal Multidisciplinary Management of Patients with Moderate to Severe Pain in Knee Osteoarthritis: A Need to Meet Patient Expectations149
Acknowledgement to Referees142
Alcohol-Associated Liver Disease: Evolving Concepts and Treatments132
Asthma and Cardiovascular Diseases: Navigating Mutual Pharmacological Interferences129
Aprocitentan: First Approval129
Vorasidenib: First Approval127
Senaparib: First Approval120
Analysis of Cerebrospinal Fluid, Plasma β-Amyloid Biomarkers, and Cognition from a 2-Year Phase 2 Trial Evaluating Oral ALZ-801/Valiltramiprosate in APOE4 Carriers with Early Alzheimer’s Disease Using117
Teclistamab: First Approval112
Spesolimab for the Treatment of Generalized Pustular Psoriasis111
Efficacy and Safety of Plecanatide in Chinese Patients with Functional Constipation: A Phase III Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial108
Epcoritamab: First Approval108
Ivarmacitinib Sulfate: First Approval105
Olipudase Alfa: First Approval102
Cosibelimab: First Approval102
Advances in Pharmacotherapy for Menopausal Vasomotor Symptoms96
Tolebrutinib: First Approval92
Drugs in Development to Manage Acute Pain91
QT Prolongation and Risk of Death with the Use of Methadone for Chronic Cancer and Noncancer Pain: Myths or Reality?88
Lenacapavir: First Approval88
Danicopan: First Approval88
Efficacy and Safety of CDK4/6 Inhibitors: A Focus on HR+/HER2− Early Breast Cancer86
Safety of Anti-osteoarthritis Medications: A Systematic Literature Review of Post-marketing Surveillance Studies85
Repotrectinib: First Approval85
Acoltremon: First Approval84
Influenza Vaccine Effectiveness and Progress Towards a Universal Influenza Vaccine84
Emerging Therapies for Chronic Hepatitis B and the Potential for a Functional Cure83
Androgenetic Alopecia: Therapy Update80
Delgocitinib 20 mg/g Cream: A Review in Chronic Hand Eczema80
Alzheimer’s Disease: Novel Targets and Investigational Drugs for Disease Modification78
SER-109 (VOWST™): A Review in the Prevention of Recurrent Clostridioides difficile Infection73
Treatment of Cryptococcal Meningitis: How Have We Got Here and Where are We Going?73
Mazdutide: First Approval72
Cancer Pain Treatment Strategies in Patients with Cancer70
Novel Drugs for the Treatment of Pulmonary Arterial Hypertension: Where Are We Going?69
Mosunetuzumab: First Approval69
Olverembatinib: First Approval68
Relugolix/Estradiol/Norethisterone (Norethindrone) Acetate: A Review in Symptomatic Uterine Fibroids67
Managing Burning Mouth Syndrome: Current and Future Directions67
Correction to: Tapinarof Cream 1%: First Approval65
Situational Prevention of Migraine Attacks: Can Early Treatment Change the Conversation?65
Drugs Targeting Cough Receptors: New Therapeutic Options in Refractory or Unexplained Chronic Cough64
Correction to: Fenfluramine: A Review in Dravet and Lennox-Gastaut Syndromes64
Correction to: Prevention and Treatment of Monkeypox61
Taletrectinib: First Approval60
Sunvozertinib: First Approval59
The Place of Cannabinoids in the Treatment of Gynecological Pain59
Dorzagliatin: First Approval58
Pozelimab: First Approval58
Tovorafenib: First Approval57
Ifupinostat: First Approval57
Pharmacological Treatments of Temporomandibular Disorders: A Systematic Review Including a Network Meta-Analysis56
PARP Inhibition, a New Therapeutic Avenue in Patients with Prostate Cancer56
Targeting Interferon Signalling in Systemic Lupus Erythematosus: Lessons Learned53
Treatment of Ovarian Cancer Beyond PARP Inhibition: Current and Future Options53
Aligning Large Language Models with Humans: A Comprehensive Survey of ChatGPT’s Aptitude in Pharmacology51
Correction to: Concizumab: First Approval51
Targeting HER2 in Metastatic Colorectal Cancer: Current Therapies, Biomarker Refinement, and Emerging Strategies50
Recent Human Papillomavirus Vaccination is Associated with a Lower Risk of COVID-19: A US Database Cohort Study49
Pan-JAK Inhibition Across Chronic Hand Eczema and Other Cutaneous Diseases: An Updated Review on Topical Delgocitinib49
Might It Be Appropriate to Anticipate the Use of Long-Acting Muscarinic Antagonists in Asthma?49
The Utilization of the Accelerated Approval Pathway in Oncology: A Case Study of Pembrolizumab48
Correction to: Remdesivir: A Review in COVID-1948
Focus on Metformin: Its Role and Safety in Pregnancy and Beyond47
Tirzepatide: A Review in Type 2 Diabetes46
Safety and Tolerability of Glucagon-Like Peptide-1 Receptor Agonists: A State-of-the-Art Narrative Review46
Current Management of Peripheral Artery Disease: Focus on Pharmacotherapy46
Birch Bark Extract: A Review in Epidermolysis Bullosa45
Aumolertinib: A Review in Non-Small Cell Lung Cancer45
Correction: From Prospective Evaluation to Practice: Model-Informed Dose Optimization in Oncology44
Givinostat: First Approval44
Effects of Oral ALZ-801/Valiltramiprosate on Plasma Biomarkers, Brain Hippocampal Volume, and Cognition: Results of 2-Year Single-Arm, Open-Label, Phase 2 Trial in APOE4 Carriers with Early Alzheimer’43
Asciminib: First Approval43
Gepirone Extended-Release: First Approval43
Pharmacotherapy for Dravet Syndrome: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials41
Paracetamol Combination Therapy for Back Pain and Osteoarthritis: A Systematic Review and Meta-Analyses41
Ozoralizumab: First Approval41
Catumaxomab: First Approval41
Atrasentan: First Approval39
Correction: Teprotumumab: A Review in Thyroid Eye Disease39
Current and Emerging Treatments for Acid Sphingomyelinase Deficiency39
Mitapivat: A Review in Pyruvate Kinase Deficiency in Adults38
Fezolinetant: First Approval38
Current Understanding of Complement Proteins as Therapeutic Targets for the Treatment of Immunoglobulin A Nephropathy37
Omalizumab in Severe Asthma: Effect on Oral Corticosteroid Exposure and Remodeling. A Randomized Open-Label Parallel Study37
Update on Mpox Management: Epidemiology, Vaccines and Therapeutics, and Regulatory Changes37
Treatment of Non-Infectious Corneal Injury: Review of Diagnostic Agents, Therapeutic Medications, and Future Targets37
Ensitrelvir Fumaric Acid: First Approval37
Advanced-Stage Chronic Myeloid Leukemia: Options for Difficult Treatment Situations36
Futibatinib: First Approval36
Avacincaptad Pegol: First Approval36
Effectiveness of Interventions to Reduce Opioid Use After Orthopaedic Surgery: A Systematic Review of Randomised Controlled Trials35
Correction: Iptacopan: First Approval34
Eye Involvement and Management in Inherited Epidermolysis Bullosa34
Lotilaner Ophthalmic Solution 0.25%: First Approval34
Correction: Lumasiran: A Review in Primary Hyperoxaluria Type 134
Imetelstat: First Approval34
Spondyloarthropathy in Inflammatory Bowel Disease: From Pathophysiology to Pharmacological Targets34
Daratumumab: A Review in Newly Diagnosed Systemic Light Chain Amyloidosis34
Managing Pain in Fibromyalgia: Current and Future Options33
Zeprumetostat: First Approval33
Tamoxifen Dose De-Escalation: An Effective Strategy for Reducing Adverse Effects?33
Beremagene Geperpavec: First Approval32
Varenicline Solution Nasal Spray: A Review in Dry Eye Disease32
Zastaprazan: First Approval32
Gastrointestinal Dysfunction in Parkinson’s Disease32
Recent United States Developments in the Pharmacological Treatment of Dry Eye Disease32
Safety of Janus Kinase Inhibitors in Inflammatory Bowel Diseases32
Tebentafusp: First Approval32
Acknowledgement to Referees31
Global Consumption Trend of Antifungal Agents in Humans From 2008 to 2018: Data From 65 Middle- and High-Income Countries31
Authors’ Reply to Mazza et al.: “Fluvoxamine for the Early Treatment of SARS‑CoV‑2 Infection: A Review of Current Evidence”30
Revolutionary Changes in the Management of Lupus Nephritis: Towards De-Glucocorticoid or No-Glucocorticoid30
Correction to: Pharmacological Approaches to Managing Violence and Aggression in Prison Populations: Clinical and Ethical Issues30
Efficiency and Safety of Noninvasive and Intravesical Therapy for Adult Neurogenic Lower Urinary Tract Dysfunction: A Systematic Review and Network Meta-analysis of Randomized Controlled Trials30
Mavorixafor: First Approval30
Remdesivir Discontinuation Decisions Based on Thresholds of Aminotransferase in an Observational Registry30
Retifanlimab: First Approval30
Crinecerfont: First Approval30
Revumenib: First Approval29
Botulinum Toxin-A for the Treatment of Myogenous Temporomandibular Disorders: An Umbrella Review of Systematic Reviews29
Sepiapterin: First Approval29
Nogapendekin alfa Inbakicept: First Approval29
Diagnosis and Treatment of AL Amyloidosis29
Immune Mechanisms in Epileptogenesis: Update on Diagnosis and Treatment of Autoimmune Epilepsy Syndromes28
Correction to: Abrocitinib: First Approval28
Targeting the Sphingosine-1-Phosphate Pathway: New Opportunities in Inflammatory Bowel Disease Management28
Comment on: “Risk of Erectile Dysfunction in Male Patients with Gout Treated with Febuxostat or Allopurinol: A Propensity Score-Matched Cohort Study”27
Correction to: Spesolimab: First Approval27
Correction: Zastaprazan: First Approval27
Ravulizumab: A Review in Generalised Myasthenia Gravis27
Gabapentinoids for Pain: A Review of Published Comparative Effectiveness Trials and Data Submitted to the FDA for Approval27
Correction to: Sparsentan: First Approval27
Onradivir: First Approval27
Direct-Acting Antivirals and the Risk of Arrhythmias and Conduction Disorders in Patients with Chronic Hepatitis C: A French Nationwide Cohort Study27
Combination of PARP Inhibitors and Androgen Receptor Pathway Inhibitors in Metastatic Castration-Resistant Prostate Cancer26
Methadone for Cancer Pain Management in Children: A Review of Literature26
Zolbetuximab: First Approval26
Remdesivir: A Review in COVID-1926
Moderate-Intensity Statin Plus Ezetimibe: Time to Rethink it as an Optimal Initial Lipid-Lowering Strategy26
Efficacy and Safety of Sovateltide in Patients with Acute Cerebral Ischaemic Stroke: A Randomised, Double-Blind, Placebo-Controlled, Multicentre, Phase III Clinical Trial26
Keverprazan Hydrochloride: First Approval26
Publisher Correction: Efficacy and Safety of RBX2660 in PUNCH CD3, a Phase III, Randomized, Double-Blind, Placebo-Controlled Trial with a Bayesian Primary Analysis for the Prevention of Recurrent Clos25
Ripretinib: A Review in Gastrointestinal Stromal Tumours as Fourth-or Later-Line of Therapy25
Lecanemab: First Approval25
Marstacimab: First Approval25
Daridorexant: First Approval25
Molnupiravir: First Approval25
Association of Metformin with the Mortality and Incidence of Cardiovascular Events in Patients with Pre-existing Cardiovascular Diseases25
Novel Drug Therapeutics in Celiac Disease: A Pipeline Review25
Antibacterials with Novel Chemical Scaffolds in Clinical Development25
Treatment of Osteoporosis and Osteoarthritis in the Oldest Old25
Spesolimab: First Approval24
Nadofaragene Firadenovec: First Approval24
Refractory Systemic Lupus Erythematosus: Identification and Pharmacological Management24
Gefapixant: First Approval24
Correction to: Mavacamten: First Approval24
Elranatamab: First Approval24
A Review of RRx-001: A Late-Stage Multi-Indication Inhibitor of NLRP3 Activation and Chronic Inflammation24
Pucotenlimab: First Approval23
Correction to: Rozanolixizumab: First Approval23
Tixagevimab + Cilgavimab: First Approval23
Comment on: “Managing Diabetic Foot Ulcers: Pharmacotherapy for Wound Healing”23
Eplontersen: First Approval22
Comment on “Trientine Tetrahydrochloride, From Bench to Bedside: A Narrative Review”22
Tofersen: First Approval22
Risk of COVID-19 Diagnosis and Hospitalisation in Patients with Osteoarthritis or Back Pain Treated with Ibuprofen Compared to Other NSAIDs or Paracetamol: A Network Cohort Study22
Renal Safety Assessment of Lipid-Lowering Drugs: Between Old Certainties and New Questions22
Trastuzumab Rezetecan: First Approval22
Amubarvimab/Romlusevimab: First Approval22
Ritlecitinib: First Approval22
Targeted Small Molecules for Systemic Lupus Erythematosus: Drugs in the Pipeline21
Gepotidacin: First Approval21
Comment on: ‘Should We Interfere with the Interleukin-6 Receptor During COVID-19: What Do We Know?’21
Pharmacological Therapies in Paroxysmal Nocturnal Haemoglobinuria: Focus on Complement Inhibition21
Sirtuins and Cellular Senescence in Patients with Idiopathic Pulmonary Fibrosis and Systemic Autoimmune Disorders21
Correction to: Ozanimod: A Review in Ulcerative Colitis21
Elafibranor: First Approval20
Differentiating IL-23 Inhibitors in Crohn’s Disease20
Drug Survival of IL-17 and IL-23 Inhibitors for Psoriasis: A Systematic Review and Meta-Analysis20
New Developments in Glucagon Treatment for Hypoglycemia20
Benefits and Liabilities of Benzodiazepines and Z-Drugs: What We Know and What We Don’t Know20
Paltusotine: First Approval20
Ensifentrine Plus a Long-Acting Muscarinic Antagonist in COPD: A Trifunctional Dual Bronchodilation Perspective19
Talquetamab: First Approval19
PCSK9 Inhibitors: A Potential Priority Choice for Lipid Management in Patients with Diabetic Kidney Disease19
Chronic Obstructive Pulmonary Disease (COPD): Developments in Pharmacological Treatments19
Valoctocogene Roxaparvovec: First Approval19
A Meta-analysis Exploring the Efficacy of Neuropathic Pain Medication for Low Back Pain or Spine-Related Leg Pain: Is Efficacy Dependent on the Presence of Neuropathic Pain?18
First-line Immune Checkpoint Inhibitor Combinations in Metastatic Renal Cell Carcinoma: Where Are We Going, Where Have We Been?18
Motixafortide: First Approval18
Iptacopan: First Approval18
Sulbactam/Durlobactam: First Approval18
Association of Glucagon-Like Peptide-1 Receptor Agonist with Progression to Liver Cirrhosis and Alcohol-Related Admissions in Patients with Alcohol Use Disorder and Diabetes: A Retrospective Cohort St18
Sipavibart: First Approval18
TKI Treatment Sequencing in Advanced Gastrointestinal Stromal Tumors18
Vamorolone: First Approval18
PI3K Inhibitors as Potential Therapeutic Agents for the Treatment of COPD with Associated Atherosclerosis18
Tunlametinib: First Approval18
Minimal Residual Disease Negativity as the Primary Goal of Multiple Myeloma Therapy18
Correction: Senaparib: First Approval18
Intraperitoneal Chemotherapy for Unresectable Peritoneal Surface Malignancies18
20-Valent Pneumococcal Conjugate Vaccine: A Review of Its Use in Adults18
Treatment Approaches for Carbapenem-Resistant Acinetobacter baumannii Infections17
Tirzepatide: First Approval17
Vimseltinib: First Approval17
Exploring Novel Pharmacotherapy Candidates for Cannabis Use Disorder: Uncovering Promising Agents on the Horizon by Mechanism of Action17
Dimdazenil: First Approval17
Mirvetuximab Soravtansine: First Approval17
How Psychedelics Modulate Multiple Memory Mechanisms in Posttraumatic Stress Disorder17
Authors’ Reply to Colak et al.: “Managing Diabetic Foot Ulcers: Pharmacotherapy for Wound Healing”17
Linzagolix: First Approval16
Nemolizumab: First Approval16
Drug-Induced Pigmentation: A Review16
BCMA-Targeted Biologic Therapies: The Next Standard of Care in Multiple Myeloma Therapy16
Results from Expanded Access Programs: A Review of Academic Literature16
Vutrisiran: A Review in Polyneuropathy of Hereditary Transthyretin-Mediated Amyloidosis16
Overall and Sex-Specific Effect of Berberine for the Treatment of Dyslipidemia in Adults: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials16
Fitusiran: First Approval16
Cabotegravir Extended-Release Injectable Suspension: A Review in HIV-1 Pre-Exposure Prophylaxis16
Drugs in Development to Treat IgA Nephropathy15
Postpartum Depression: A Clinical Review of Impact and Current Treatment Solutions15
The Potential of RNA Therapeutics in Treating Cardiovascular Disease15
The Struggle to End a Millennia-Long Pandemic: Novel Candidate and Repurposed Drugs for the Treatment of Tuberculosis15
Treatment Options in Spinal Muscular Atrophy: A Pragmatic Approach for Clinicians15
Chinese Herbal Medicines for Coronary Heart Disease: Clinical Evidence, Pharmacological Mechanisms, and the Interaction with Gut Microbiota15
Tegileridine: First Approval15
Elinzanetant: First Approval15
Diabetes of the Exocrine Pancreas: Implications for Pharmacological Management15
Systemic Therapy for Advanced Thyroid Cancer—New Personalized Options15
Use of Levosimendan in Patients with Pulmonary Hypertension: What is the Current Evidence?15
Clesrovimab: First Approval15
Ebronucimab: First Approval15
Pirtobrutinib: First Approval15
Vonoprazan: A Review in Helicobacter pylori Infection14
GLP-1 Receptor Agonists and SGLT2 Inhibitors in Type 2 Diabetes: Pleiotropic Cardiometabolic Effects and Add-on Value of a Combined Therapy14
Anticoagulation in Chronic Kidney Disease14
Correction to: Nirmatrelvir Plus Ritonavir: First Approval14
Correction to: Daridorexant: First Approval14
Pharmacological Management of Hypertrophic Cardiomyopathy: From Bench to Bedside14
Fenfluramine: A Review in Dravet and Lennox-Gastaut Syndromes14
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