Drugs

Papers
(The median citation count of Drugs is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-11-01 to 2024-11-01.)
ArticleCitations
Prevention and Treatment of Monkeypox356
The Epidemiology and Pathogenesis and Treatment of Pseudomonas aeruginosa Infections: An Update257
BNT162b2 mRNA COVID-19 Vaccine: First Approval253
Inhibiting CDK4/6 in Breast Cancer with Palbociclib, Ribociclib, and Abemaciclib: Similarities and Differences220
The Antifungal Pipeline: Fosmanogepix, Ibrexafungerp, Olorofim, Opelconazole, and Rezafungin218
Inclisiran: First Approval208
Lumasiran: First Approval187
Nirmatrelvir Plus Ritonavir: First Approval179
Acute Pancreatitis: Diagnosis and Treatment176
Casimersen: First Approval164
Aducanumab: First Approval156
Sotorasib: First Approval132
Efficacy and Safety of RBX2660 in PUNCH CD3, a Phase III, Randomized, Double-Blind, Placebo-Controlled Trial with a Bayesian Primary Analysis for the Prevention of Recurrent Clostridioides difficile I125
TRPV1-Targeted Drugs in Development for Human Pain Conditions120
Setmelanotide: First Approval111
Managing Diabetic Foot Ulcers: Pharmacotherapy for Wound Healing110
Abuse and Misuse of Pregabalin and Gabapentin: A Systematic Review Update110
Sphingosine 1-phosphate Receptor Modulator Therapy for Multiple Sclerosis: Differential Downstream Receptor Signalling and Clinical Profile Effects102
Targeting Sphingosine-1-Phosphate Signaling in Immune-Mediated Diseases: Beyond Multiple Sclerosis101
Nivolumab Plus Relatlimab: First Approval89
Orelabrutinib: First Approval86
REGN-EB3: First Approval85
Deucravacitinib: First Approval84
Amivantamab: First Approval82
Lonafarnib: First Approval81
Remimazolam: A Review in Procedural Sedation80
Novel Agents for the Pharmacological Treatment of Alcohol Use Disorder78
Fabry Disease: The Current Treatment Landscape78
Faricimab: First Approval75
Belzutifan: First Approval75
Abrocitinib: First Approval71
Pralsetinib: First Approval70
Disitamab Vedotin: First Approval70
Savolitinib: First Approval70
Vutrisiran: First Approval69
Cannabinoid Formulations and Delivery Systems: Current and Future Options to Treat Pain67
Nintedanib: A Review in Fibrotic Interstitial Lung Diseases66
Tisotumab Vedotin: First Approval65
Updated Overall Survival in a Randomized Study Comparing Dacomitinib with Gefitinib as First-Line Treatment in Patients with Advanced Non-Small-Cell Lung Cancer and EGFR-Activating Mutations64
Molnupiravir: First Approval63
Cadonilimab: First Approval63
Anti-Amyloid Monoclonal Antibodies are Transformative Treatments that Redefine Alzheimer's Disease Therapeutics62
MicroRNA Mimics or Inhibitors as Antiviral Therapeutic Approaches Against COVID-1961
Telitacicept: First Approval60
Casirivimab/Imdevimab: First Approval60
Current Status of Clinical Trials on Tau Immunotherapies60
Trilaciclib: First Approval60
Cefiderocol: A Review in Serious Gram-Negative Bacterial Infections60
Efgartigimod: First Approval59
Contezolid: First Approval58
Loncastuximab Tesirine: First Approval57
Third-Generation Antiseizure Medications for Adjunctive Treatment of Focal-Onset Seizures in Adults: A Systematic Review and Network Meta-analysis57
Infigratinib: First Approval57
Tebentafusp: First Approval57
Targeting AMPK by Statins: A Potential Therapeutic Approach57
Lecanemab: First Approval57
Imipenem/Cilastatin/Relebactam: A Review in Gram-Negative Bacterial Infections56
Treating Head and Neck Cancer in the Age of Immunotherapy: A 2023 Update55
Tirzepatide: First Approval55
Envafolimab: First Approval55
Ocrelizumab: A Review in Multiple Sclerosis55
Pharmacotherapy of Generalized Myasthenia Gravis with Special Emphasis on Newer Biologicals54
Dostarlimab: First Approval54
Pegcetacoplan: First Approval53
Umbralisib: First Approval52
Antipsychotic Polypharmacy for the Management of Schizophrenia: Evidence and Recommendations52
Filgotinib: First Approval50
Tremelimumab: First Approval50
Safety, Immunogenicity and Interchangeability of Biosimilar Monoclonal Antibodies and Fusion Proteins: A Regulatory Perspective50
Nirsevimab: First Approval50
Naxitamab: First Approval49
Donafenib: First Approval49
Fuzuloparib: First Approval47
Delandistrogene Moxeparvovec: First Approval47
Odevixibat: First Approval47
Cholestatic Liver Disease: Current Treatment Strategies and New Therapeutic Agents47
Anifrolumab: First Approval47
Teclistamab: First Approval46
Regdanvimab: First Approval46
Therapeutic Options in Hereditary Optic Neuropathies46
Trastuzumab Deruxtecan-Induced Interstitial Lung Disease/Pneumonitis in ERBB2-Positive Advanced Solid Malignancies: A Systematic Review46
Givosiran: A Review in Acute Hepatic Porphyria46
Mavacamten: First Approval46
Mirvetuximab Soravtansine: First Approval45
Thrombopoietin Receptor Agonists (TPO-RAs): Drug Class Considerations for Pharmacists45
The Development of Cladribine Tablets for the Treatment of Multiple Sclerosis: A Comprehensive Review45
Androgenetic Alopecia: Therapy Update44
Lazertinib: First Approval44
Adagrasib: First Approval44
Spesolimab: First Approval43
Tezepelumab: First Approval43
Valoctocogene Roxaparvovec: First Approval43
Etranacogene Dezaparvovec: First Approval42
Voclosporin: First Approval42
Sotrovimab: First Approval41
Mosunetuzumab: First Approval41
A Pharmacological and Clinical Overview of Oral Semaglutide for the Treatment of Type 2 Diabetes41
Pamiparib: First Approval40
Daridorexant: First Approval40
Avacopan: First Approval40
Melphalan Flufenamide (Melflufen): First Approval39
Asciminib: First Approval39
Finerenone: First Approval39
Vericiguat: First Approval39
Pacritinib: First Approval38
Mobocertinib: First Approval38
Pharmacotherapy for Amyotrophic Lateral Sclerosis: A Review of Approved and Upcoming Agents38
Overview of DaxibotulinumtoxinA for Injection: A Novel Formulation of Botulinum Toxin Type A38
Epidemiology, Treatments, and Vaccine Development for Antimicrobial-Resistant Neisseria gonorrhoeae: Current Strategies and Future Directions37
Tixagevimab + Cilgavimab: First Approval37
Lenacapavir: First Approval37
REal worlD Effectiveness and Safety of Mepolizumab in a Multicentric Spanish Cohort of Asthma Patients Stratified by Eosinophils: The REDES Study37
Evinacumab: First Approval37
Ozoralizumab: First Approval36
Olverembatinib: First Approval36
Ibrexafungerp: First Approval36
Futibatinib: First Approval36
Margetuximab: First Approval36
Neuronal Ceroid Lipofuscinosis: Potential for Targeted Therapy36
Ansuvimab: First Approval36
Tofersen: First Approval36
Atogepant: First Approval36
Are New Antiretroviral Treatments Increasing the Risk of Weight Gain?35
Ofatumumab: A Review in Relapsing Forms of Multiple Sclerosis34
Phase 3, Randomized, 20-Month Study of the Efficacy and Safety of Bimatoprost Implant in Patients with Open-Angle Glaucoma and Ocular Hypertension (ARTEMIS 2)34
Bruton’s Tyrosine Kinase Inhibition as an Emerging Therapy in Systemic Autoimmune Disease33
Maralixibat: First Approval33
Clinical Implementation of Biologics and Small Molecules in the Treatment of Hidradenitis Suppurativa33
Tapinarof Cream 1%: First Approval32
Hyperkalemia in Chronic Kidney Disease in the New Era of Kidney Protection Therapies31
Difelikefalin: First Approval31
Treatment of Non-Infectious Corneal Injury: Review of Diagnostic Agents, Therapeutic Medications, and Future Targets30
Belumosudil: First Approval30
Alzheimer’s Disease: Novel Targets and Investigational Drugs for Disease Modification30
Biosimilar-to-Biosimilar Switching: What is the Rationale and Current Experience?30
Treatment of Cryptococcal Meningitis: How Have We Got Here and Where are We Going?30
The Potential Role of Clinical Metagenomics in Infectious Diseases: Therapeutic Perspectives30
Omaveloxolone: First Approval30
Entrectinib: A Review in NTRK+ Solid Tumours and ROS1+ NSCLC30
Pimitespib: First Approval30
Hetrombopag: First Approval29
Prior Treatment with Statins is Associated with Improved Outcomes of Patients with COVID-19: Data from the SEMI-COVID-19 Registry29
Oteseconazole: First Approval29
Nemolizumab: First Approval29
Ocular Toxicity of Targeted Anticancer Agents28
Tralokinumab: First Approval28
Global Consumption Trend of Antifungal Agents in Humans From 2008 to 2018: Data From 65 Middle- and High-Income Countries28
Ganaxolone: First Approval28
Ritlecitinib: First Approval27
Pharmacological Management of Hypertrophic Cardiomyopathy: From Bench to Bedside27
The Effects of Osteoporotic and Non-osteoporotic Medications on Fracture Risk and Bone Mineral Density27
Secukinumab: A Review in Psoriatic Arthritis27
Avatrombopag: A Review in Thrombocytopenia26
Enarodustat: First Approval26
Dose Tapering of Biologics in Patients with Psoriasis: A Scoping Review26
Bone Mineral Density Loss and Fracture Risk After Discontinuation of Anti-osteoporotic Drug Treatment: A Narrative Review26
Tapentadol Versus Tramadol: A Narrative and Comparative Review of Their Pharmacological, Efficacy and Safety Profiles in Adult Patients26
Alemtuzumab: A Review in Relapsing Remitting Multiple Sclerosis26
Fluvoxamine for the Early Treatment of SARS-CoV-2 Infection: A Review of Current Evidence26
The Role of Vitamin D in Health and Disease: A Narrative Review on the Mechanisms Linking Vitamin D with Disease and the Effects of Supplementation25
Lefamulin: A Novel Oral and Intravenous Pleuromutilin for the Treatment of Community-Acquired Bacterial Pneumonia25
Evolving Strategies in the Treatment of Anaemia in Chronic Kidney Disease: The HIF-Prolyl Hydroxylase Inhibitors25
The Struggle to End a Millennia-Long Pandemic: Novel Candidate and Repurposed Drugs for the Treatment of Tuberculosis25
Furmonertinib: First Approval24
Nadofaragene Firadenovec: First Approval24
Benefits and Harms of ‘Smart Drugs’ (Nootropics) in Healthy Individuals24
Maribavir: First Approval24
Vedolizumab and Extraintestinal Manifestations in Inflammatory Bowel Disease24
Contemporary Management of Dyslipidemia24
Estetrol/Drospirenone: A Review in Oral Contraception23
Vosoritide: First Approval23
Ponesimod: First Approval23
New Topical Therapies in Development for Atopic Dermatitis23
Serplulimab: First Approval23
Netupitant/Palonosetron: A Review in Chemotherapy-Induced Nausea and Vomiting23
Safety of Janus Kinase Inhibitors in Inflammatory Bowel Diseases23
Elacestrant: First Approval22
Pharmacotherapeutic Treatment of Glioblastoma: Where Are We to Date?22
Ozanimod: A Review in Ulcerative Colitis22
Pharmacotherapy for Hospitalized Patients with COVID-19: Treatment Patterns by Disease Severity22
Baricitinib for the Treatment of Alopecia Areata22
Emerging Options for the Prevention and Management of Clostridioides difficile Infection22
Failed, Interrupted, or Inconclusive Trials on Neuroprotective and Neuroregenerative Treatment Strategies in Multiple Sclerosis: Update 2015–202021
Bupivacaine/Meloxicam Prolonged Release: A Review in Postoperative Pain21
Nedosiran: First Approval21
Retifanlimab: First Approval21
Personalized Multimorbidity Management for Patients with Type 2 Diabetes Using Reinforcement Learning of Electronic Health Records21
A Role for SGLT-2 Inhibitors in Treating Non-diabetic Chronic Kidney Disease21
Tirbanibulin: First Approval21
Pathophysiology and Management of Variceal Bleeding21
Olipudase Alfa: First Approval21
Avacincaptad Pegol: First Approval21
Gefapixant: First Approval21
Rezafungin: First Approval21
Drug Treatment of Cluster Headache21
Current Medical Therapy for Adenomyosis: From Bench to Bedside21
Budesonide/Glycopyrronium/Formoterol: A Review in COPD20
Pirtobrutinib: First Approval20
Bimekizumab for the Treatment of Psoriasis20
Pharmacologic Management of Persistent Pain in Cancer Survivors20
Avalglucosidase alfa: First Approval20
Targeted Therapy Approaches for MET Abnormalities in Non-Small Cell Lung Cancer20
Insights Into the Results of Sotagliflozin Cardiovascular Outcome Trials: Is Dual Inhibition the Cherry on the Cake of Cardiorenal Protection?20
Glofitamab: First Approval20
New Drug Delivery Systems Developed for Brain Targeting19
Targeting Acquired and Intrinsic Resistance Mechanisms in Epidermal Growth Factor Receptor Mutant Non-Small-Cell Lung Cancer19
Ravulizumab: A Review in Atypical Haemolytic Uraemic Syndrome19
Mechanisms of Neutralizing Anti-drug Antibody Formation and Clinical Relevance on Therapeutic Efficacy of Enzyme Replacement Therapies in Fabry Disease19
Sparsentan: First Approval19
Cancer Pain Treatment Strategies in Patients with Cancer19
Olanzapine/Samidorphan: First Approval19
Valemetostat Tosilate: First Approval19
Surufatinib: First Approval19
Clinical Value of Emerging Bioanalytical Methods for Drug Measurements: A Scoping Review of Their Applicability for Medication Adherence and Therapeutic Drug Monitoring18
Amubarvimab/Romlusevimab: First Approval18
A Review of RRx-001: A Late-Stage Multi-Indication Inhibitor of NLRP3 Activation and Chronic Inflammation18
Penpulimab: First Approval18
Improving Treatment Options for Primary Hyperoxaluria18
Inhaled Corticosteroids in Adults with Non-cystic Fibrosis Bronchiectasis: From Bench to Bedside. A Narrative Review18
Multimodal Multidisciplinary Management of Patients with Moderate to Severe Pain in Knee Osteoarthritis: A Need to Meet Patient Expectations18
Fostamatinib: A Review in Chronic Immune Thrombocytopenia18
Sulopenem: An Intravenous and Oral Penem for the Treatment of Urinary Tract Infections Due to Multidrug-Resistant Bacteria18
Cannabis-Based Medicines and Medical Cannabis in the Treatment of Nociplastic Pain17
Sugemalimab: First Approval17
Chiglitazar: First Approval17
Neoadjuvant and Adjuvant Systemic Therapy for Early-Stage Non-small-Cell Lung Cancer17
Berotralstat: First Approval17
Association of Metformin with the Mortality and Incidence of Cardiovascular Events in Patients with Pre-existing Cardiovascular Diseases17
Recent Clinical Trials Insights into the Treatment of Primary Membranous Nephropathy16
Targeting the Angiopoietin/Tie Pathway: Prospects for Treatment of Retinal and Respiratory Disorders16
Talquetamab: First Approval15
Clazosentan: First Approval15
Evolution of Type 2 Diabetes Management from a Glucocentric Approach to Cardio-Renal Risk Reduction: The New Paradigm of Care15
Immune Mechanisms in Epileptogenesis: Update on Diagnosis and Treatment of Autoimmune Epilepsy Syndromes15
Fezolinetant: First Approval15
Recent Advances in Antiarrhythmic Drug Therapy15
Resmetirom: First Approval15
Varenicline Solution Nasal Spray: A Review in Dry Eye Disease15
From a Symptom-Based to a Mechanism-Based Pharmacotherapeutic Treatment in Complex Regional Pain Syndrome15
Imeglimin: Current Development and Future Potential in Type 2 Diabetes15
Current and Future Treatment Landscape for Idiopathic Pulmonary Fibrosis15
Drugs in Clinical Development to Treat Autosomal Dominant Polycystic Kidney Disease15
Zavegepant: First Approval15
Imeglimin Hydrochloride: First Approval14
IL-31 Inhibition as a Therapeutic Approach for the Management of Chronic Pruritic Dermatoses14
Treatment Sequencing for Anaplastic Lymphoma Kinase-Rearranged Non-Small-Cell Lung Cancer14
Inhaled Phosphodiesterase Inhibitors for the Treatment of Chronic Obstructive Pulmonary Disease14
Detecting and Targeting NTRK Fusions in Cancer in the Era of Tumor Agnostic Oncology14
Antithrombotic Therapy for Symptomatic Peripheral Arterial Disease: A Systematic Review and Network Meta-Analysis14
Dasiglucagon: First Approval14
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