Drugs

Article	Citations
Acknowledgement to Referees	503
Comment on “Recent Human Papillomavirus Vaccination is Associated with a Lower Risk of COVID-19: A US Database Cohort Study”	322
Targeting DNA Damage Response Deficiency in Thoracic Cancers	285
Suprachoroidal Space Triamcinolone Acetonide: A Review in Uveitic Macular Edema	270
Correction: New Pharmacologic Approaches to the Treatment of Bipolar Depression	232
Correction: Targeting KRASG12C in Non-Small-Cell Lung Cancer: Current Standards and Developments	206
Asthma and Cardiovascular Diseases: Navigating Mutual Pharmacological Interferences	177
Analysis of Cerebrospinal Fluid, Plasma β-Amyloid Biomarkers, and Cognition from a 2-Year Phase 2 Trial Evaluating Oral ALZ-801/Valiltramiprosate in APOE4 Carriers with Early Alzheimer’s Disease Using	174
Eftrenonacog Alfa: A Review in Haemophilia B	171
Spesolimab for the Treatment of Generalized Pustular Psoriasis	158
Authors’ Reply to Toda: Multimodal Multidisciplinary Management of Patients with Moderate to Severe Pain in Knee Osteoarthritis: A Need to Meet Patient Expectations	154
Aztreonam-Avibactam: A Review in the Treatment of Serious Bacterial Infections Caused by Aerobic Gram-Negative Organisms	149
Senaparib: First Approval	142
New Therapies on the Horizon for Primary Biliary Cholangitis	135
Vorasidenib: First Approval	131
Aprocitentan: First Approval	114
Teclistamab: First Approval	111
Epcoritamab: First Approval	108
Clinical Efficacy, Safety and Imaging Effects of Oral Valiltramiprosate in APOEε4/ε4 Homozygotes with Early Alzheimer’s Disease: Results of the Phase III, Randomized, Double-Blind, Placebo-Controlled,	107
Alcohol-Associated Liver Disease: Evolving Concepts and Treatments	99
Efficacy and Safety of Plecanatide in Chinese Patients with Functional Constipation: A Phase III Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial	99
Drugs in Development to Manage Acute Pain	97
Emerging Therapies for Chronic Hepatitis B and the Potential for a Functional Cure	96
Tolebrutinib: First Approval	95
Efficacy and Harms of Opioid Analgesics for Acute Pain: Overview of Systematic Reviews and Meta-analyses	92

Advances in Pharmacotherapy for Menopausal Vasomotor Symptoms	92
Danicopan: First Approval	91
Repotrectinib: First Approval	86
Safety of Anti-osteoarthritis Medications: A Systematic Literature Review of Post-marketing Surveillance Studies	86
Efficacy and Safety of CDK4/6 Inhibitors: A Focus on HR+/HER2− Early Breast Cancer	84
Acoltremon: First Approval	83
QT Prolongation and Risk of Death with the Use of Methadone for Chronic Cancer and Noncancer Pain: Myths or Reality?	82
Cosibelimab: First Approval	81
Androgenetic Alopecia: Therapy Update	79
Lenacapavir: First Approval	79
Ivarmacitinib Sulfate: First Approval	78
Influenza Vaccine Effectiveness and Progress Towards a Universal Influenza Vaccine	74
Cancer Pain Treatment Strategies in Patients with Cancer	72
Relugolix/Estradiol/Norethisterone (Norethindrone) Acetate: A Review in Symptomatic Uterine Fibroids	72
Treatment of Cryptococcal Meningitis: How Have We Got Here and Where are We Going?	70
Sibeprenlimab: First Approval	69
Novel Drugs for the Treatment of Pulmonary Arterial Hypertension: Where Are We Going?	69
Mazdutide: First Approval	68
Classic Psychedelics for Chronic Pain: A Critical Review of the Literature and Practical Advice for Clinicians	66
Alzheimer’s Disease: Novel Targets and Investigational Drugs for Disease Modification	65
Delgocitinib 20 mg/g Cream: A Review in Chronic Hand Eczema	65
SER-109 (VOWST™): A Review in the Prevention of Recurrent Clostridioides difficile Infection	63
Drugs Targeting Cough Receptors: New Therapeutic Options in Refractory or Unexplained Chronic Cough	62
Pozelimab: First Approval	61
Correction to: Fenfluramine: A Review in Dravet and Lennox-Gastaut Syndromes	60
Correction to: Tapinarof Cream 1%: First Approval	60
Situational Prevention of Migraine Attacks: Can Early Treatment Change the Conversation?	59
Taletrectinib: First Approval	57
Ifupinostat: First Approval	55
Correction to: Prevention and Treatment of Monkeypox	53
The Place of Cannabinoids in the Treatment of Gynecological Pain	52
Botulinum Toxin Type A for Trigeminal and Postherpetic Neuralgia: An Umbrella Review of Systematic Reviews	51
Sunvozertinib: First Approval	51
Aligning Large Language Models with Humans: A Comprehensive Survey of ChatGPT’s Aptitude in Pharmacology	50
Managing Burning Mouth Syndrome: Current and Future Directions	50
Comparative Efficacy of Non-opioid Analgesic Drugs for Chronic Cancer Pain: A Bayesian Network Meta-analysis	50
Pixavir Marboxil: First Approval	50
Targeting Interferon Signalling in Systemic Lupus Erythematosus: Lessons Learned	49
Treatment of Ovarian Cancer Beyond PARP Inhibition: Current and Future Options	48
Targeting Inflammation in Bronchiectasis	48
Pharmacological Treatments of Temporomandibular Disorders: A Systematic Review Including a Network Meta-Analysis	47
Tovorafenib: First Approval	47
Correction to: Concizumab: First Approval	46
Dorzagliatin: First Approval	46
Antiseizure Medications that Did Not Reach the Epilepsy Market: An Assessment of Factors Contributing to Their Failed Clinical Development Over the Last Three Decades	45
Pharmacological Management of Obesity in Pregnancy: A Review of Current and Emerging Therapies	44
Correction: From Prospective Evaluation to Practice: Model-Informed Dose Optimization in Oncology	44
Correction to: Remdesivir: A Review in COVID-19	44
Pharmacotherapy for Dravet Syndrome: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials	43
Recent Human Papillomavirus Vaccination is Associated with a Lower Risk of COVID-19: A US Database Cohort Study	43

Focus on Metformin: Its Role and Safety in Pregnancy and Beyond	43
The Utilization of the Accelerated Approval Pathway in Oncology: A Case Study of Pembrolizumab	43
Advances in Immune-Based Approaches for the Cure of HIV Infection	43
Ozoralizumab: First Approval	42
Pan-JAK Inhibition Across Chronic Hand Eczema and Other Cutaneous Diseases: An Updated Review on Topical Delgocitinib	42
Birch Bark Extract: A Review in Epidermolysis Bullosa	42
Safety and Tolerability of Glucagon-Like Peptide-1 Receptor Agonists: A State-of-the-Art Narrative Review	42
Paracetamol Combination Therapy for Back Pain and Osteoarthritis: A Systematic Review and Meta-Analyses	42
Effects of Oral ALZ-801/Valiltramiprosate on Plasma Biomarkers, Brain Hippocampal Volume, and Cognition: Results of 2-Year Single-Arm, Open-Label, Phase 2 Trial in APOE4 Carriers with Early Alzheimer’	41
Might It Be Appropriate to Anticipate the Use of Long-Acting Muscarinic Antagonists in Asthma?	41
Givinostat: First Approval	40
Catumaxomab: First Approval	39
Gepirone Extended-Release: First Approval	39
Fezolinetant: First Approval	38
Targeting HER2 in Metastatic Colorectal Cancer: Current Therapies, Biomarker Refinement, and Emerging Strategies	38
Tirzepatide: A Review in Type 2 Diabetes	38
Becotatug Vedotin: First Approval	37
Current and Emerging Treatments for Acid Sphingomyelinase Deficiency	37
Polidocanol in Sclerotherapy for Lymphovenous Disorders: Mechanisms, Clinical Uses, and Future Prospects	37
Correction: Ifupinostat: First Approval	37
Futibatinib: First Approval	36
Current Understanding of Complement Proteins as Therapeutic Targets for the Treatment of Immunoglobulin A Nephropathy	36
Sequential Use of Trastuzumab Deruxtecan and Sacituzumab Govitecan in Patients with Breast Cancer: A Pharmacological Approach to Support the Clinical Rationale	36
Ensitrelvir Fumaric Acid: First Approval	36
Relacorilant: First Approval	35
Antifungal Treatment Regimens as Primary Therapy for Invasive Aspergillosis: A Systematic Review and Network Meta-analysis	35
Avacincaptad Pegol: First Approval	34
Mitapivat: A Review in Pyruvate Kinase Deficiency in Adults	34
Atrasentan: First Approval	34
Omalizumab in Severe Asthma: Effect on Oral Corticosteroid Exposure and Remodeling. A Randomized Open-Label Parallel Study	34
Update on Mpox Management: Epidemiology, Vaccines and Therapeutics, and Regulatory Changes	34
Correction: Teprotumumab: A Review in Thyroid Eye Disease	34
Correction: Iptacopan: First Approval	34
Tamoxifen Dose De-Escalation: An Effective Strategy for Reducing Adverse Effects?	33
Managing Pain in Fibromyalgia: Current and Future Options	33
Effectiveness of Interventions to Reduce Opioid Use After Orthopaedic Surgery: A Systematic Review of Randomised Controlled Trials	33
Beremagene Geperpavec: First Approval	33
Zeprumetostat: First Approval	33
Advanced-Stage Chronic Myeloid Leukemia: Options for Difficult Treatment Situations	33
Eye Involvement and Management in Inherited Epidermolysis Bullosa	32
Recent United States Developments in the Pharmacological Treatment of Dry Eye Disease	32
Oral Gut-Restricted Targeted Therapy for IBD: A Pipeline Review	32
Zastaprazan: First Approval	31
Imetelstat: First Approval	31
Correction: Lumasiran: A Review in Primary Hyperoxaluria Type 1	31
Varenicline Solution Nasal Spray: A Review in Dry Eye Disease	31
Lotilaner Ophthalmic Solution 0.25%: First Approval	31
Safety of Janus Kinase Inhibitors in Inflammatory Bowel Diseases	31
Remdesivir Discontinuation Decisions Based on Thresholds of Aminotransferase in an Observational Registry	30
Acknowledgement to Referees	30
Nogapendekin alfa Inbakicept: First Approval	30
EGFR Exon 20 Insertion–Mutated Non-Small Cell Lung Cancer: Current Treatment Landscape and Future Directions	29
Revolutionary Changes in the Management of Lupus Nephritis: Towards De-Glucocorticoid or No-Glucocorticoid	29
Etripamil: First Approval	29
Sepiapterin: First Approval	29
Targeting the Sphingosine-1-Phosphate Pathway: New Opportunities in Inflammatory Bowel Disease Management	29
Crinecerfont: First Approval	29
Rovadicitinib: First Approval	28
Revumenib: First Approval	28
Efficiency and Safety of Noninvasive and Intravesical Therapy for Adult Neurogenic Lower Urinary Tract Dysfunction: A Systematic Review and Network Meta-analysis of Randomized Controlled Trials	28
Retifanlimab: First Approval	28
Botulinum Toxin-A for the Treatment of Myogenous Temporomandibular Disorders: An Umbrella Review of Systematic Reviews	28
Diagnosis and Treatment of AL Amyloidosis	28
Immune Mechanisms in Epileptogenesis: Update on Diagnosis and Treatment of Autoimmune Epilepsy Syndromes	27
Correction to: Spesolimab: First Approval	27
Methadone for Cancer Pain Management in Children: A Review of Literature	27
Mavorixafor: First Approval	27
Tradipitant: First Approval	27
Correction to: Sparsentan: First Approval	27
Comment on: “Risk of Erectile Dysfunction in Male Patients with Gout Treated with Febuxostat or Allopurinol: A Propensity Score-Matched Cohort Study”	27
Direct-Acting Antivirals and the Risk of Arrhythmias and Conduction Disorders in Patients with Chronic Hepatitis C: A French Nationwide Cohort Study	27
Correction: Zastaprazan: First Approval	27
Efficacy and Safety of Sovateltide in Patients with Acute Cerebral Ischaemic Stroke: A Randomised, Double-Blind, Placebo-Controlled, Multicentre, Phase III Clinical Trial	26
Ravulizumab: A Review in Generalised Myasthenia Gravis	26
Gabapentinoids for Pain: A Review of Published Comparative Effectiveness Trials and Data Submitted to the FDA for Approval	25
Combination of PARP Inhibitors and Androgen Receptor Pathway Inhibitors in Metastatic Castration-Resistant Prostate Cancer	25
Keverprazan Hydrochloride: First Approval	25
Remdesivir: A Review in COVID-19	25
Onradivir: First Approval	25
Moderate-Intensity Statin Plus Ezetimibe: Time to Rethink it as an Optimal Initial Lipid-Lowering Strategy	25

Zolbetuximab: First Approval	25
Refractory Systemic Lupus Erythematosus: Identification and Pharmacological Management	24
Publisher Correction: Efficacy and Safety of RBX2660 in PUNCH CD3, a Phase III, Randomized, Double-Blind, Placebo-Controlled Trial with a Bayesian Primary Analysis for the Prevention of Recurrent Clos	24
Spesolimab: First Approval	24
Ripretinib: A Review in Gastrointestinal Stromal Tumours as Fourth-or Later-Line of Therapy	24
Current and Future Pharmacological Interventions for Acquired Hypothalamic Obesity	24
Elranatamab: First Approval	24
Nadofaragene Firadenovec: First Approval	24
Antibacterials with Novel Chemical Scaffolds in Clinical Development	24
Novel Drug Therapeutics in Celiac Disease: A Pipeline Review	24
Lecanemab: First Approval	24
A Review of RRx-001: A Late-Stage Multi-Indication Inhibitor of NLRP3 Activation and Chronic Inflammation	24
Treatment of Osteoporosis and Osteoarthritis in the Oldest Old	23
Correction to: Rozanolixizumab: First Approval	23
Marstacimab: First Approval	23
Biologics and Small Molecule Inhibitors: Novel Therapeutic Strategies for Cutaneous Adverse Drug Reactions	23
Ziftomenib: First Approval	23
Amubarvimab/Romlusevimab: First Approval	23
Antibody–Drug Conjugates in Non-small Cell Lung Cancer	23
DLL3-Targeted Strategies in Advanced Prostate Cancer: Current Evidence and Future Perspectives	23
Renal Safety Assessment of Lipid-Lowering Drugs: Between Old Certainties and New Questions	23
Linerixibat: First Approval	23
Pucotenlimab: First Approval	22
Comment on “Trientine Tetrahydrochloride, From Bench to Bedside: A Narrative Review”	22
Zongertinib: First Approval	22
Risk of COVID-19 Diagnosis and Hospitalisation in Patients with Osteoarthritis or Back Pain Treated with Ibuprofen Compared to Other NSAIDs or Paracetamol: A Network Cohort Study	22
Ritlecitinib: First Approval	22
Tofersen: First Approval	22
Benefits and Liabilities of Benzodiazepines and Z-Drugs: What We Know and What We Don’t Know	21
Large Vessel Vasculitis: Recent Advances in Pathophysiology and Targeted Therapies	21
Targeted Small Molecules for Systemic Lupus Erythematosus: Drugs in the Pipeline	21
Paltusotine: First Approval	21
Differentiating IL-23 Inhibitors in Crohn’s Disease	21
Pharmacological Therapies in Paroxysmal Nocturnal Haemoglobinuria: Focus on Complement Inhibition	21
Comment on: ‘Should We Interfere with the Interleukin-6 Receptor During COVID-19: What Do We Know?’	21
Sirtuins and Cellular Senescence in Patients with Idiopathic Pulmonary Fibrosis and Systemic Autoimmune Disorders	20
Chronic Obstructive Pulmonary Disease (COPD): Developments in Pharmacological Treatments	20
Correction to: Ozanimod: A Review in Ulcerative Colitis	20
Drug Survival of IL-17 and IL-23 Inhibitors for Psoriasis: A Systematic Review and Meta-Analysis	20
Talquetamab: First Approval	20
Elafibranor: First Approval	20
Gepotidacin: First Approval	20
Association of Glucagon-Like Peptide-1 Receptor Agonist with Progression to Liver Cirrhosis and Alcohol-Related Admissions in Patients with Alcohol Use Disorder and Diabetes: A Retrospective Cohort St	20
Sipavibart: First Approval	20
Valoctocogene Roxaparvovec: First Approval	20
Trastuzumab Rezetecan: First Approval	20
Eplontersen: First Approval	20
Correction: Senaparib: First Approval	20
Exploring Novel Pharmacotherapy Candidates for Cannabis Use Disorder: Uncovering Promising Agents on the Horizon by Mechanism of Action	19
Ensifentrine Plus a Long-Acting Muscarinic Antagonist in COPD: A Trifunctional Dual Bronchodilation Perspective	19
Minimal Residual Disease Negativity as the Primary Goal of Multiple Myeloma Therapy	19
Iptacopan: First Approval	19
Tunlametinib: First Approval	19
TKI Treatment Sequencing in Advanced Gastrointestinal Stromal Tumors	19
PI3K Inhibitors as Potential Therapeutic Agents for the Treatment of COPD with Associated Atherosclerosis	19
Pharmacological, Natural and Emerging Therapies for Meibomian Gland Dysfunction: A Review	19
Dimdazenil: First Approval	19
A Meta-analysis Exploring the Efficacy of Neuropathic Pain Medication for Low Back Pain or Spine-Related Leg Pain: Is Efficacy Dependent on the Presence of Neuropathic Pain?	19
Vamorolone: First Approval	18
Tegileridine: First Approval	18
Linzagolix: First Approval	18
Sulbactam/Durlobactam: First Approval	18
Treatment Approaches for Carbapenem-Resistant Acinetobacter baumannii Infections	18
Clesrovimab: First Approval	18
Results from Expanded Access Programs: A Review of Academic Literature	18
Postpartum Depression: A Clinical Review of Impact and Current Treatment Solutions	18
Motixafortide: First Approval	18
How Psychedelics Modulate Multiple Memory Mechanisms in Posttraumatic Stress Disorder	18
Mirvetuximab Soravtansine: First Approval	18
Drugs in Development to Treat IgA Nephropathy	18
Cabotegravir Extended-Release Injectable Suspension: A Review in HIV-1 Pre-Exposure Prophylaxis	18
PCSK9 Inhibitors: A Potential Priority Choice for Lipid Management in Patients with Diabetic Kidney Disease	18
Intraperitoneal Chemotherapy for Unresectable Peritoneal Surface Malignancies	18
Biased Kappa-opioid Agonist Strategies in Pain Management: Approaches to Clinical Benefits with Reduced Adverse Effects	17
Vutrisiran: A Review in Polyneuropathy of Hereditary Transthyretin-Mediated Amyloidosis	17
Fitusiran: First Approval	17
Vimseltinib: First Approval	17
Use of Levosimendan in Patients with Pulmonary Hypertension: What is the Current Evidence?	17
Chinese Herbal Medicines for Coronary Heart Disease: Clinical Evidence, Pharmacological Mechanisms, and the Interaction with Gut Microbiota	17
Drug-Induced Pigmentation: A Review	17
Overall and Sex-Specific Effect of Berberine for the Treatment of Dyslipidemia in Adults: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials	17
Treatment Options in Spinal Muscular Atrophy: A Pragmatic Approach for Clinicians	17
Anticoagulation in Chronic Kidney Disease	17
Managing Psoriatic Arthritis Patients Presenting with Axial Symptoms	17
Weight Loss Versus Glycemic Control as the Primary Treatment Target in Newly Diagnosed Type 2 Diabetes: Why Choose When You Can Have Both?	16
Elinzanetant: First Approval	16
Ebronucimab: First Approval	16
HIV Pre-Exposure Prophylaxis: New and Upcoming Drugs to Address the HIV Epidemic	16
Current and Emerging Therapies for Lysosomal Storage Disorders	16
Rezvilutamide: First Approval	16
Systemic Therapy for Advanced Thyroid Cancer—New Personalized Options	16
Extended and Continuous Infusion of Novel Protected β-Lactam Antibiotics: A Narrative Review	15
Correction to: Suprachoroidal Space Triamcinolone Acetonide: A Review in Uveitic Macular Edema	15
Fenfluramine: A Review in Dravet and Lennox-Gastaut Syndromes	15
The Potential of RNA Therapeutics in Treating Cardiovascular Disease	15