Developmental Biology

Article	Citations
Pattern formation mechanisms of self-organizing reaction-diffusion systems	95
YAP1 and its fusion proteins in cancer initiation, progression and therapeutic resistance	61
What are you synching about? Emerging complexity of Notch signaling in the segmentation clock	44
The conserved and divergent roles of Prdm3 and Prdm16 in zebrafish and mouse craniofacial development	39
Cell competition: A historical perspective	35
Modeling human embryo development with embryonic and extra-embryonic stem cells	35
Human gastrulation: The embryo and its models	34
The developmental biology of kinesins	30
Chromatin accessibility and histone acetylation in the regulation of competence in early development	28
Seeing stars: Development and function of retinal astrocytes	26
Postembryonic screen for mutations affecting spine development in zebrafish	24
A developmental perspective on the evolution of the nervous system	24
Neural crest metabolism: At the crossroads of development and disease	24
Development and maintenance of vision’s first synapse	23
Vascular deficiencies in renal organoids and ex vivo kidney organogenesis	23
Vitamin A1/A2 chromophore exchange: Its role in spectral tuning and visual plasticity	23
Role of RB1 in human embryonic stem cell-derived retinal organoids	23
Evolution of organoid technology: Lessons learnt in Co-Culture systems from developmental biology	23
Cell competition-induced apical elimination of transformed cells, EDAC, orchestrates the cellular homeostasis	23
Identification of novel human Wnt target genes using adult endodermal tissue-derived organoids	23
SHROOM3 is downstream of the planar cell polarity pathway and loss-of-function results in congenital heart defects	22
Molecular mechanisms regulating axon responsiveness at the midline	22
Retinoic acid signaling restricts the size of the first heart field within the anterior lateral plate mesoderm	22
Formation and contraction of multicellular actomyosin cables facilitate lens placode invagination	21
Mechanisms of vitamin A metabolism and deficiency in the mammalian and fly visual system	21

A systematic, label-free method for identifying RNA-associated proteins in vivo provides insights into vertebrate ciliary beating machinery	21
The role of Xenopus developmental biology in unraveling Wnt signalling and antero-posterior axis formation	21
Gastruloids: Pluripotent stem cell models of mammalian gastrulation and embryo engineering	20
Developmental basis of trachea-esophageal birth defects	20
Build me up optic cup: Intrinsic and extrinsic mechanisms of vertebrate eye morphogenesis	20
Trim-Away mediated knock down uncovers a new function for Lbh during gastrulation of Xenopus laevis.	20
Developmental origins of transgenerational sperm histone retention following ancestral exposures	20
Lamellipodia-like protrusions and focal adhesions contribute to collective cell migration in zebrafish	19
Cell fusion is differentially regulated in zebrafish post-embryonic slow and fast muscle	19
Wnt signaling determines body axis polarity in regenerating Hydra tissue fragments	19
Conditional gene knockdowns in sea urchins using caged morpholinos	19
There and back again: The mechanisms of differentiation and transdifferentiation in Drosophila blood cells	19
Conserved and context-dependent roles for pdgfrb signaling during zebrafish vascular mural cell development	19
BMP signaling plays a role in anterior-neural/head development, but not organizer activity, in the gastropod Crepidula fornicata	19
Ets1 functions partially redundantly with Etv2 to promote embryonic vasculogenesis and angiogenesis in zebrafish	19
Shark and ray genomics for disentangling their morphological diversity and vertebrate evolution	19
MicroRNA-21 is involved in oocyte maturation, blastocyst formation, and pre-implantation embryo development	19
Neural-fated self-renewing cells regulated by Sox2 during secondary neurulation in chicken tail bud	19
The role of cnidarian developmental biology in unraveling axis formation and Wnt signaling	18
The (unusual) heuristic value of Hox gene clusters; a matter of time?	18
Temporal single-cell transcriptomes of zebrafish spinal cord pMN progenitors reveal distinct neuronal and glial progenitor populations	18
VEGF signaling activates the matrix metalloproteinases, MmpL7 and MmpL5 at the sites of active skeletal growth and MmpL7 regulates skeletal elongation	18
Temporal progression of Drosophila medulla neuroblasts generates the transcription factor combination to control T1 neuron morphogenesis	18
Human neural organoids: Models for developmental neurobiology and disease	18
Epigenetic regulation of drosophila germline stem cell maintenance and differentiation	18
Histone methyltransferase activity programs nuclear peripheral genome positioning	17
Prdm1 overexpression causes a photoreceptor fate-shift in nascent, but not mature, bipolar cells	17
Context-specific functions of Notch in Drosophila blood cell progenitors	17
Balancing energy expenditure and storage with growth and biosynthesis during Drosophila development	17
The actin polymerization factor Diaphanous and the actin severing protein Flightless I collaborate to regulate sarcomere size	16
Full of potential: Pluripotent stem cells for the systems biology of embryonic patterning	16
Modeling mammalian trunk development in a dish	16
Evo-Devo of Urbilateria and its larval forms	16
A single-cell guide to retinal development: Cell fate decisions of multipotent retinal progenitors in scRNA-seq	16
OFCD syndrome and extraembryonic defects are revealed by conditional mutation of the Polycomb-group repressive complex 1.1 (PRC1.1) gene BCOR	16
Wnt/β-catenin signaling acts cell-autonomously to promote cardiomyocyte regeneration in the zebrafish heart	16
Developmental plasticity and the response to nutrient stress in Caenorhabditis elegans	15
CRISPR-Cas9 editing of non-coding genomic loci as a means of controlling gene expression in the sea urchin	15
Fish models for investigating nutritional regulation of embryonic development	15
Human retinal model systems: Strengths, weaknesses, and future directions	15
CBP/p300 homologs CBP2 and CBP3 play distinct roles in planarian stem cell function	15
Multiple roles for Pax2 in the embryonic mouse eye	15
Single-cell transcriptomics in the Drosophila visual system: Advances and perspectives on cell identity regulation, connectivity, and neuronal diversity evolution	15
Transcriptional mechanisms of motor neuron development in vertebrates and invertebrates	15
The FGF-AKT pathway is necessary for cardiomyocyte survival for heart regeneration in zebrafish	15
An exciting period of Drosophila developmental biology: Of imaginal discs, clones, compartments, parasegments and homeotic genes	15
Hexagonal patterning of the Drosophila eye	15
Development and diversification of bipolar interneurons in the mammalian retina	15
The evolutionary history and spectral tuning of vertebrate visual opsins	14
Mcrs1 interacts with Six1 to influence early craniofacial and otic development	14

Nucleoporin NUP205 plays a critical role in cilia and congenital disease	14
Molecular detection of maturation stages in the developing kidney	14
CREB-binding protein (CBP) gene family regulates planarian survival and stem cell differentiation	14
Pdgfra regulates multipotent cell differentiation towards chondrocytes via inhibiting Wnt9a/beta-catenin pathway during chondrocranial cartilage development	14
Rethinking embryology in vitro: A synergy between engineering, data science and theory	14
The embryonic origin of periodic color patterns	14
Nutrient availability contributes to a graded refractory period for regeneration in Xenopus tropicalis	14
Wnt/β-catenin signaling pathway regulates cell proliferation but not muscle dedifferentiation nor apoptosis during sea cucumber intestinal regeneration	14
DNA methylation and the core pluripotency network	14
Transcriptional and epigenetic control of hematopoietic stem cell fate decisions in vertebrates	14
The developmental transcriptome for Lytechinus variegatus exhibits temporally punctuated gene expression changes	14
Reassembling gastrulation	14
The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation	14
Mouse models to study the pathophysiology of combined methylmalonic acidemia and homocystinuria, cblC type	14
Cell shape changes during larval body plan development in Clytia hemisphaerica	13
Development of the vertebrate retinal direction-selective circuit	13
FGF signaling promotes myoblast proliferation through activation of wingless signaling	13
Knock-in mutations of scarecrow, a Drosophila homolog of mammalian Nkx2.1, reveal a novel function required for development of the optic lobe in Drosophila melanogaster	13
Expression of Hey2 transcription factor in the early embryonic ventricles is controlled through a distal enhancer by Tbx20 and Gata transcription factors	13
A conserved role for arrow in posterior axis patterning across Arthropoda	13
A brief history of the segmentation clock	13
The mTOR pathway component Unkempt regulates neural stem cell and neural progenitor cell cycle in the Drosophila central nervous system	13
Temperature-Induced uncoupling of cell cycle regulators	13
Returning to kidney development to deliver synthetic kidneys	13
The forkhead factor Foxl2 participates in the ovarian differentiation of Chinese soft-shelled turtle Pelodiscus sinensis	13
Extra-genomic instructive influences in morphogenesis: A review of external signals that regulate growth and form	12
Transcriptional profiling from whole embryos to single neuroblast lineages in Drosophila	12
A conserved node in the regulation of Vasa between an induced and an inherited program of primordial germ cell specification	12
Development and regeneration dynamics of the Medaka notochord	12
Mechanosignaling in vertebrate development	12
Essential function and targets of BMP signaling during midbrain neural crest delamination	12
IGF1R constitutive activation expands luminal progenitors and influences lineage differentiation during breast tumorigenesis	12
The unfolding of the Hippo signaling pathway	12
Visualizing mesoderm and neural crest cell dynamics during chick head morphogenesis	12
The tissues and regulatory pattern of limb chondrogenesis	12
The great small organisms of developmental genetics: Caenorhabditis elegans and Drosophila melanogaster	12
Development and regeneration of the crushing dentition in skates (Rajidae)	12
Method for disarranging the pigment pattern of zebrafish by optogenetics	11
Apcdd1 is a dual BMP/Wnt inhibitor in the developing nervous system and skin	11
Notch-mediated lateral induction is necessary to maintain vestibular prosensory identity during inner ear development	11
Heparan sulfate proteoglycans regulate BMP signalling during neural crest induction	11
Is zebrafish heart regeneration “complete”? Lineage-restricted cardiomyocytes proliferate to pre-injury numbers but some fail to differentiate in fibrotic hearts	11
Non-coding RNAs repressive role in post-transcriptional processing of RUNX2 during the acquisition of the osteogenic phenotype of periodontal ligament mesenchymal stem cells	11
Progenitors in prostate development and disease	11
Zebrafish can regenerate endoskeleton in larval pectoral fin but the regenerative ability declines	11
Speeding up anterior-posterior patterning of insects by differential initialization of the gap gene cascade	11
Development and patterning of rib primordia are dependent on associated musculature	11
CRISPR/Cas9-mediated mutation reveals Pax6 is essential for development of the compound eye in Decapoda Exopalaemon carinicauda	11
The role of glucose in physiological and pathological heart formation	11
Hif1α and Wnt are required for posterior gene expression during Xenopus tropicalis tail regeneration	11
Leucine zipper transcription factor-like 1 (LZTFL1), an intraflagellar transporter protein 27 (IFT27) associated protein, is required for normal sperm function and male fertility	11
Inferring temporal organization of postembryonic development from high-content behavioral tracking	11
ShapeMetrics: A userfriendly pipeline for 3D cell segmentation and spatial tissue analysis	11
Diverse cellular origins of adult blood vascular endothelial cells	11
Role of cell competition in ageing	11
An optimized QF-binary expression system for use in zebrafish	10
Drosophila E93 promotes adult development and suppresses larval responses to ecdysone during metamorphosis	10
Conservation as well as divergence in Mcidas function underlies the differentiation of multiciliated cells in vertebrates	10
Foxa1 and Foxa2 orchestrate development of the urethral tube and division of the embryonic cloaca through an autoregulatory loop with Shh	10
Physiological electric fields induce directional migration of mammalian cranial neural crest cells	10
Immunoglobulin superfamily receptor Junctional adhesion molecule 3 (Jam3) requirement for melanophore survival and patterning during formation of zebrafish stripes	10
The Hox protein conundrum: The “specifics” of DNA binding for Hox proteins and their partners	10
Chromatin remodeler CHD7 is critical for cochlear morphogenesis and neurosensory patterning	10
In silico analysis of inner ear development using public whole embryonic body single-cell RNA-sequencing data	10
Orchestration of the distinct morphogenetic movements in different tissues drives tail regression during ascidian metamorphosis	10
Dynamic transcription regulation at the single-molecule level	10
Patterning via local cell-cell interactions in developing systems	10
Multiple roles of Pax6 in postnatal cornea development	10
Long-lived zebrafish Rohon-Beard cells	10
Reflections on the past, present and future of developmental biology	10
Wampa is a dynein subunit required for axonemal assembly and male fertility in Drosophila	10
Mef2c factors are required for early but not late addition of cardiomyocytes to the ventricle	10
Natural size variation among embryos leads to the corresponding scaling in gene expression	10
WNT signalling supported by MEK/ERK inhibition is essential to maintain pluripotency in bovine preimplantation embryo	10
The conserved alternative splicing factor caper regulates neuromuscular phenotypes during development and aging	9
BMP signalling is required for extra-embryonic ectoderm development during pre-to-post-implantation transition of the mouse embryo	9
Basal epidermis collective migration and local Sonic hedgehog signaling promote skeletal branching morphogenesis in zebrafish fins	9
Shedding light into the black box: Advances in in vitro systems for studying implantation	9
Anomalous incisor morphology indicates tissue-specific roles for Tfap2a and Tfap2b in tooth development	9
Desert hedgehog-primary cilia cross talk shapes mitral valve tissue by organizing smooth muscle actin	9

Synthetic by design: Exploiting tissue self-organization to explore early human embryology	9
Role of BMP signaling during early development of the annelid Capitella teleta	9
Stressful development: integrating endoderm development, stress, and longevity	9
YAP/TAZ maintain the proliferative capacity and structural organization of radial glial cells during brain development	9
A cell-based boundary model of gastrulation by unipolar ingression in the hydrozoan cnidarian Clytia hemisphaerica	9
Dally-like protein sequesters multiple Wnt ligands in the Drosophila germarium	9
Dynamic optima in cell sizes during early development enable normal gastrulation in zebrafish embryos	9
DNA methylation dynamics underlie metamorphic gene regulation programs in Xenopus tadpole brain	9
Autophagy induction in tumor surrounding cells promotes tumor growth in adult Drosophila intestines	9
Natural genetic engineering: A programmed chromosome/DNA elimination	9
Thyroid hormone regulates abrupt skin morphogenesis during zebrafish postembryonic development	9
A comprehensive in vivo screen for anti-apoptotic miRNAs indicates broad capacities for oncogenic synergy	9
Semper's cells in the insect compound eye: Insights into ocular form and function	9
microRNA-31 regulates skeletogenesis by direct suppression of Eve and Wnt1	8
Loss of Smad4 in the scleraxis cell lineage results in postnatal joint contracture	8
Cell culture system to assay candidate genes and molecular pathways implicated in congenital diaphragmatic hernias	8
An efficient miRNA knockout approach using CRISPR-Cas9 in Xenopus	8
Localized translation on the mitotic apparatus: A history and perspective	8
Zebrafish mutants in vegfab can affect endothelial cell proliferation without altering ERK phosphorylation and are phenocopied by loss of PI3K signaling	8
Scribble mutation disrupts convergent extension and apical constriction during mammalian neural tube closure	8
The function of the axon initial segment in neuronal polarity	8
Keratin 13 deficiency causes white sponge nevus in mice	8
Integrin α5 and Integrin α4 cooperate to promote endocardial differentiation and heart morphogenesis	8
The role of cell lineage in the development of neuronal circuitry and function	8
Migratory patterns and evolutionary plasticity of cranial neural crest cells in ray-finned fishes	8
Deletion of the Dishevelled family of genes disrupts anterior-posterior axis specification and selectively prevents mesoderm differentiation	8
Lymphatic endothelial cell fate specification in the mammalian embryo: An historical perspective	8
A proteomics approach identifies novel resident zebrafish Balbiani body proteins Cirbpa and Cirbpb	8
Microtubule organization of vertebrate sensory neurons in vivo	8
ETS factors are required but not sufficient for specific patterns of enhancer activity in different endothelial subtypes	8
The axonemal dynein heavy chain 10 gene is essential for monocilia motility and spine alignment in zebrafish	8
Reconstructing the evolutionary history of the oxytocin and vasotocin receptor gene family: Insights on whole genome duplication scenarios	8
GCN5 acetylation is required for craniofacial chondrocyte maturation	8
The nephric mesenchyme lineage of intermediate mesoderm is derived from Tbx6-expressing derivatives of neuro-mesodermal progenitors via BMP-dependent Osr1 function	8
A single-cell RNA-seq analysis of Brachyury-expressing cell clusters suggests a morphogenesis-associated signal center of oral ectoderm in sea urchin embryos	8
The diversity of invertebrate visual opsins spanning Protostomia, Deuterostomia, and Cnidaria	8
Nervous system and tissue polarity dynamically adapt to new morphologies in planaria	8
Zfh-2 facilitates Notch-induced apoptosis in the CNS and appendages of Drosophila melanogaster	8
Asymmetric organelle positioning during epithelial polarization of C. elegans intestinal cells	7
Temporal cell fate determination in the spinal cord is mediated by the duration of Notch signalling	7
Unifying synthetic embryology	7
Profiling NSD3-dependent neural crest gene expression reveals known and novel candidate regulatory factors	7
Diacylglycerol, PKC and MAPK signaling initiate tubeworm metamorphosis in response to bacteria	7
Hormone-related genes heterochronically and modularly regulate neotenic differentiation in termites	7
Of mice and plants: Comparative developmental systems biology	7
HAND transcription factors cooperatively specify the aorta and pulmonary trunk	7
Molecular mechanisms of hearing loss in Nager syndrome	7
Multi-organ transcriptomic landscape of Ambystoma velasci metamorphosis	7
A dynamic cell recruitment process drives growth of the Drosophila wing by overscaling the vestigial expression pattern	7
Optic vesicle morphogenesis requires primary cilia	7
Variability in β-catenin pulse dynamics in a stochastic cell fate decision in C. elegans	7
IMPDH forms the cytoophidium in zebrafish	7
Effects of aging on urinary tract epithelial homeostasis and immunity	7
Coup-TF: A maternal factor essential for differentiation along the embryonic axes in the sea urchin Paracentrotus lividus	7
Optimizing CRISPR/Cas9-based gene manipulation in echinoderms	7
Spatio-temporal immunolocalization of VEGF-A, Runx2, and osterix during the early steps of intramembranous ossification of the alveolar process in rat embryos	7
Dysregulated BMP signaling through ACVR1 impairs digit joint development in fibrodysplasia ossificans progressiva (FOP)	7
Digit specific denervation does not inhibit mouse digit tip regeneration	7
Temporospatial regulation of intraflagellar transport is required for the endochondral ossification in mice	7
Tbx15/18/22 shares a binding site with Tbx6-r.b to maintain expression of a muscle structural gene in ascidian late embryos	7
Spatiotemporal mapping of sensory and motor innervation of the embryonic and postnatal mouse urinary bladder	7
The role of mechanosensor Piezo1 in bone homeostasis and mechanobiology	7
A single-cell RNA-seq analysis of early larval cell-types of the starfish, Patiria pectinifera: Insights into evolution of the chordate body plan	7
Mask, a component of the Hippo pathway, is required for Drosophila eye morphogenesis	7
The dynamics of morphogenesis in stem cell-based embryology: Novel insights for symmetry breaking	7
A novel gene trap line for visualization and manipulation of erbb3b+ neural crest and glial cells in zebrafish	7