Developmental Biology

Article	Citations
YAP1 and its fusion proteins in cancer initiation, progression and therapeutic resistance	84
Human gastrulation: The embryo and its models	41
Cell competition: A historical perspective	40
Modeling human embryo development with embryonic and extra-embryonic stem cells	39
The developmental biology of kinesins	34
Seeing stars: Development and function of retinal astrocytes	32
The role of cnidarian developmental biology in unraveling axis formation and Wnt signaling	29
Postembryonic screen for mutations affecting spine development in zebrafish	29
A developmental perspective on the evolution of the nervous system	29
Vitamin A1/A2 chromophore exchange: Its role in spectral tuning and visual plasticity	29
Gastruloids: Pluripotent stem cell models of mammalian gastrulation and embryo engineering	27
Mechanisms of vitamin A metabolism and deficiency in the mammalian and fly visual system	27
Vascular deficiencies in renal organoids and ex vivo kidney organogenesis	27
Evolution of organoid technology: Lessons learnt in Co-Culture systems from developmental biology	27
Conserved and context-dependent roles for pdgfrb signaling during zebrafish vascular mural cell development	27
Development and maintenance of vision’s first synapse	26
Identification of novel human Wnt target genes using adult endodermal tissue-derived organoids	26
Neural crest metabolism: At the crossroads of development and disease	26
The (unusual) heuristic value of Hox gene clusters; a matter of time?	26
Cell competition-induced apical elimination of transformed cells, EDAC, orchestrates the cellular homeostasis	26
VEGF signaling activates the matrix metalloproteinases, MmpL7 and MmpL5 at the sites of active skeletal growth and MmpL7 regulates skeletal elongation	26
Retinoic acid signaling restricts the size of the first heart field within the anterior lateral plate mesoderm	25
The evolutionary history and spectral tuning of vertebrate visual opsins	24
Wnt signaling determines body axis polarity in regenerating Hydra tissue fragments	24
Lamellipodia-like protrusions and focal adhesions contribute to collective cell migration in zebrafish	24

Shark and ray genomics for disentangling their morphological diversity and vertebrate evolution	24
Build me up optic cup: Intrinsic and extrinsic mechanisms of vertebrate eye morphogenesis	23
Developmental basis of trachea-esophageal birth defects	23
A systematic, label-free method for identifying RNA-associated proteins in vivo provides insights into vertebrate ciliary beating machinery	23
A single-cell guide to retinal development: Cell fate decisions of multipotent retinal progenitors in scRNA-seq	23
Conditional gene knockdowns in sea urchins using caged morpholinos	23
MicroRNA-21 is involved in oocyte maturation, blastocyst formation, and pre-implantation embryo development	23
The role of Xenopus developmental biology in unraveling Wnt signalling and antero-posterior axis formation	23
There and back again: The mechanisms of differentiation and transdifferentiation in Drosophila blood cells	22
A brief history of the segmentation clock	21
Wnt/β-catenin signaling acts cell-autonomously to promote cardiomyocyte regeneration in the zebrafish heart	21
Human neural organoids: Models for developmental neurobiology and disease	21
The unfolding of the Hippo signaling pathway	21
Development and diversification of bipolar interneurons in the mammalian retina	21
Trim-Away mediated knock down uncovers a new function for Lbh during gastrulation of Xenopus laevis.	20
Balancing energy expenditure and storage with growth and biosynthesis during Drosophila development	20
Hexagonal patterning of the Drosophila eye	20
Molecular detection of maturation stages in the developing kidney	20
Developmental plasticity and the response to nutrient stress in Caenorhabditis elegans	19
CRISPR-Cas9 editing of non-coding genomic loci as a means of controlling gene expression in the sea urchin	19
Epigenetic regulation of drosophila germline stem cell maintenance and differentiation	19
Evo-Devo of Urbilateria and its larval forms	19
Fish models for investigating nutritional regulation of embryonic development	19
Transcriptional and epigenetic control of hematopoietic stem cell fate decisions in vertebrates	19
Temporal single-cell transcriptomes of zebrafish spinal cord pMN progenitors reveal distinct neuronal and glial progenitor populations	19
Wnt/β-catenin signaling pathway regulates cell proliferation but not muscle dedifferentiation nor apoptosis during sea cucumber intestinal regeneration	18
OFCD syndrome and extraembryonic defects are revealed by conditional mutation of the Polycomb-group repressive complex 1.1 (PRC1.1) gene BCOR	18
Modeling mammalian trunk development in a dish	18
The FGF-AKT pathway is necessary for cardiomyocyte survival for heart regeneration in zebrafish	18
Diverse cellular origins of adult blood vascular endothelial cells	18
Human retinal model systems: Strengths, weaknesses, and future directions	18
Nucleoporin NUP205 plays a critical role in cilia and congenital disease	18
The actin polymerization factor Diaphanous and the actin severing protein Flightless I collaborate to regulate sarcomere size	17
Multiple roles for Pax2 in the embryonic mouse eye	17
A conserved role for arrow in posterior axis patterning across Arthropoda	16
Progenitors in prostate development and disease	16
The great small organisms of developmental genetics: Caenorhabditis elegans and Drosophila melanogaster	16
Development of the vertebrate retinal direction-selective circuit	16
Hif1α and Wnt are required for posterior gene expression during Xenopus tropicalis tail regeneration	15
The role of mechanosensor Piezo1 in bone homeostasis and mechanobiology	15
Nutrient availability contributes to a graded refractory period for regeneration in Xenopus tropicalis	15
A conserved node in the regulation of Vasa between an induced and an inherited program of primordial germ cell specification	15
Cell shape changes during larval body plan development in Clytia hemisphaerica	15
Returning to kidney development to deliver synthetic kidneys	15
Single-cell transcriptomics in the Drosophila visual system: Advances and perspectives on cell identity regulation, connectivity, and neuronal diversity evolution	15
CBP/p300 homologs CBP2 and CBP3 play distinct roles in planarian stem cell function	15
An exciting period of Drosophila developmental biology: Of imaginal discs, clones, compartments, parasegments and homeotic genes	15
Mouse models to study the pathophysiology of combined methylmalonic acidemia and homocystinuria, cblC type	15
CREB-binding protein (CBP) gene family regulates planarian survival and stem cell differentiation	15
Rethinking embryology in vitro: A synergy between engineering, data science and theory	14

Temperature-Induced uncoupling of cell cycle regulators	14
The forkhead factor Foxl2 participates in the ovarian differentiation of Chinese soft-shelled turtle Pelodiscus sinensis	14
Drosophila E93 promotes adult development and suppresses larval responses to ecdysone during metamorphosis	14
Effects of aging on urinary tract epithelial homeostasis and immunity	14
Transcriptional mechanisms of motor neuron development in vertebrates and invertebrates	14
Mcrs1 interacts with Six1 to influence early craniofacial and otic development	14
Reassembling gastrulation	14
Transcriptional profiling from whole embryos to single neuroblast lineages in Drosophila	14
Reflections on the past, present and future of developmental biology	13
Mechanosignaling in vertebrate development	13
The role of glucose in physiological and pathological heart formation	13
Essential function and targets of BMP signaling during midbrain neural crest delamination	13
Stressful development: integrating endoderm development, stress, and longevity	13
Thyroid hormone regulates abrupt skin morphogenesis during zebrafish postembryonic development	12
Leucine zipper transcription factor-like 1 (LZTFL1), an intraflagellar transporter protein 27 (IFT27) associated protein, is required for normal sperm function and male fertility	12
Development and patterning of rib primordia are dependent on associated musculature	12
Non-coding RNAs repressive role in post-transcriptional processing of RUNX2 during the acquisition of the osteogenic phenotype of periodontal ligament mesenchymal stem cells	12
Physiological electric fields induce directional migration of mammalian cranial neural crest cells	12
Inferring temporal organization of postembryonic development from high-content behavioral tracking	12
A proteomics approach identifies novel resident zebrafish Balbiani body proteins Cirbpa and Cirbpb	12
Role of BMP signaling during early development of the annelid Capitella teleta	12
Basal epidermis collective migration and local Sonic hedgehog signaling promote skeletal branching morphogenesis in zebrafish fins	12
Is zebrafish heart regeneration “complete”? Lineage-restricted cardiomyocytes proliferate to pre-injury numbers but some fail to differentiate in fibrotic hearts	12
Temporal cell fate determination in the spinal cord is mediated by the duration of Notch signalling	11
Zebrafish mutants in vegfab can affect endothelial cell proliferation without altering ERK phosphorylation and are phenocopied by loss of PI3K signaling	11
A comprehensive in vivo screen for anti-apoptotic miRNAs indicates broad capacities for oncogenic synergy	11
A single-cell RNA-seq analysis of Brachyury-expressing cell clusters suggests a morphogenesis-associated signal center of oral ectoderm in sea urchin embryos	11
Immunoglobulin superfamily receptor Junctional adhesion molecule 3 (Jam3) requirement for melanophore survival and patterning during formation of zebrafish stripes	11
Migratory patterns and evolutionary plasticity of cranial neural crest cells in ray-finned fishes	11
Semper's cells in the insect compound eye: Insights into ocular form and function	11
Mef2c factors are required for early but not late addition of cardiomyocytes to the ventricle	11
The Hox protein conundrum: The “specifics” of DNA binding for Hox proteins and their partners	11
Anomalous incisor morphology indicates tissue-specific roles for Tfap2a and Tfap2b in tooth development	11
YAP/TAZ maintain the proliferative capacity and structural organization of radial glial cells during brain development	10
Multiple roles of Pax6 in postnatal cornea development	10
Zebrafish her3 knockout impacts developmental and cancer-related gene signatures	10
Synthetic by design: Exploiting tissue self-organization to explore early human embryology	10
Urp1 and Urp2 act redundantly to maintain spine shape in zebrafish larvae	10
Zfh-2 facilitates Notch-induced apoptosis in the CNS and appendages of Drosophila melanogaster	10
The axonemal dynein heavy chain 10 gene is essential for monocilia motility and spine alignment in zebrafish	10
Dynamic transcription regulation at the single-molecule level	10
Natural genetic engineering: A programmed chromosome/DNA elimination	10
The function of the axon initial segment in neuronal polarity	10
Role of cell competition in ageing	10
Hormone-related genes heterochronically and modularly regulate neotenic differentiation in termites	10
BMP signalling is required for extra-embryonic ectoderm development during pre-to-post-implantation transition of the mouse embryo	10
Microtubule organization of vertebrate sensory neurons in vivo	10
Loss of Smad4 in the scleraxis cell lineage results in postnatal joint contracture	10
Tie1 regulates zebrafish cardiac morphogenesis through Tolloid-like 1 expression	10
Chromatin remodeler CHD7 is critical for cochlear morphogenesis and neurosensory patterning	10
In silico analysis of inner ear development using public whole embryonic body single-cell RNA-sequencing data	10
Dynamic optima in cell sizes during early development enable normal gastrulation in zebrafish embryos	10
Localized translation on the mitotic apparatus: A history and perspective	10
Digit specific denervation does not inhibit mouse digit tip regeneration	10
E-liquids and vanillin flavoring disrupts retinoic acid signaling and causes craniofacial defects in Xenopus embryos	10
The conserved alternative splicing factor caper regulates neuromuscular phenotypes during development and aging	9
The nephric mesenchyme lineage of intermediate mesoderm is derived from Tbx6-expressing derivatives of neuro-mesodermal progenitors via BMP-dependent Osr1 function	9
Scribble mutation disrupts convergent extension and apical constriction during mammalian neural tube closure	9
A role for sustained MAPK activity in the mouse ventral telencephalon	9
Optimizing CRISPR/Cas9-based gene manipulation in echinoderms	9
Reconstructing the evolutionary history of the oxytocin and vasotocin receptor gene family: Insights on whole genome duplication scenarios	9
HAND transcription factors cooperatively specify the aorta and pulmonary trunk	9
The dynamics of morphogenesis in stem cell-based embryology: Novel insights for symmetry breaking	9
Wound repair in sea urchin larvae involves pigment cells and blastocoelar cells	9
Nervous system and tissue polarity dynamically adapt to new morphologies in planaria	9
A fishy tail: Insights into the cell and molecular biology of neuromesodermal cells from zebrafish embryos	9
microRNA-31 regulates skeletogenesis by direct suppression of Eve and Wnt1	9
A novel gene trap line for visualization and manipulation of erbb3b+ neural crest and glial cells in zebrafish	9
The diversity of invertebrate visual opsins spanning Protostomia, Deuterostomia, and Cnidaria	9
Autophagy induction in tumor surrounding cells promotes tumor growth in adult Drosophila intestines	9
ETS factors are required but not sufficient for specific patterns of enhancer activity in different endothelial subtypes	9
Microtubule polarity is instructive for many aspects of neuronal polarity	9
An enhancer located in a Pde6c intron drives transient expression in the cone photoreceptors of developing mouse and human retinas	8
Coup-TF: A maternal factor essential for differentiation along the embryonic axes in the sea urchin Paracentrotus lividus	8
Gene regulatory divergence amongst echinoderms underlies appearance of pigment cells in sea urchin development	8
Spatio-temporal immunolocalization of VEGF-A, Runx2, and osterix during the early steps of intramembranous ossification of the alveolar process in rat embryos	8
The embryonic origin of primordial germ cells in the tardigrade Hypsibius exemplaris	8
Non-targeted lipidomics and transcriptomics analysis reveal the molecular underpinnings of mandibular gland development in Apis mellifera ligustica	8
Asymmetric organelle positioning during epithelial polarization of C. elegans intestinal cells	8
The exocyst complex is required for developmental and regenerative neurite growth in vivo	8

The role of cell lineage in the development of neuronal circuitry and function	8
Cdc42 has important roles in postnatal angiogenesis and vasculature formation	8
IMPDH forms the cytoophidium in zebrafish	8
Diacylglycerol, PKC and MAPK signaling initiate tubeworm metamorphosis in response to bacteria	8
Human lung organoid: Models for respiratory biology and diseases	8
Principles of microtubule polarity in linear cells	8
Patterning of cartilaginous condensations in the developing facial skeleton	8
An efficient miRNA knockout approach using CRISPR-Cas9 in Xenopus	8
Anterior lateral plate mesoderm gives rise to multiple tissues and requires tbx5a function in left-right asymmetry, migration dynamics, and cell specification of late-addition cardiac cells	8
Temporospatial regulation of intraflagellar transport is required for the endochondral ossification in mice	8
Unifying synthetic embryology	8
Cell culture system to assay candidate genes and molecular pathways implicated in congenital diaphragmatic hernias	8
Sox10-cre BAC transgenes reveal temporal restriction of mesenchymal cranial neural crest and identify glandular Sox10 expression	8
A role for Cep70 in centriole amplification in multiciliated cells	8
High-throughput methodology to identify CRISPR-generated Danio rerio mutants using fragment analysis with unmodified PCR products	8
Cardiomyocyte heterogeneity during zebrafish development and regeneration	8
Dysregulated BMP signaling through ACVR1 impairs digit joint development in fibrodysplasia ossificans progressiva (FOP)	8
Lymphatic endothelial cell fate specification in the mammalian embryo: An historical perspective	8
Dendrite regeneration in the vertebrate spinal cord	8
Keratin 13 deficiency causes white sponge nevus in mice	8
A reverse genetic approach in geckos with the CRISPR/Cas9 system by oocyte microinjection	8
Profiling NSD3-dependent neural crest gene expression reveals known and novel candidate regulatory factors	8
Evolutionary conservation of maternal RNA localization in fishes and amphibians revealed by TOMO-Seq	8
Molecular mechanisms of hearing loss in Nager syndrome	7
Tbx15/18/22 shares a binding site with Tbx6-r.b to maintain expression of a muscle structural gene in ascidian late embryos	7
Spatiotemporal mapping of sensory and motor innervation of the embryonic and postnatal mouse urinary bladder	7
Cyclin D1 gene expression is essential for cell cycle progression from the maternal-to-zygotic transition during blastoderm development in Japanese quail	7
Iron overload during the embryonic period develops hyperactive like behavior and dysregulation of biogenic amines in Drosophila melanogaster	7
Polychrome labeling reveals skeletal triradiate and elongation dynamics and abnormalities in patterning cue-perturbed embryos	7
Lfng and Dll3 cooperate to modulate protein interactions in cis and coordinate oscillatory Notch pathway activation in the segmentation clock	7
Interplay between sex determination cascade and major signaling pathways during Drosophila eye development: Perspectives for future research	7
Alterations in the spatiotemporal expression of the chemokine receptor CXCR4 in endothelial cells cause failure of hierarchical vascular branching	7
Misregulation of cell adhesion molecules in the Ciona neural tube closure mutant bugeye	7
Arid1a regulates bladder urothelium formation and maintenance	7
microRNA-124 directly suppresses Nodal and Notch to regulate mesodermal development	7
Brain endothelial cells acquire blood-brain barrier properties in the absence of Vegf-dependent CNS angiogenesis	7
Spatiotemporal transcriptional dynamics of the cycling mouse oviduct	7
Expanding the boundaries of synthetic development	7
Metabolic regulation of cell competition	7
Distinct Frizzled receptors independently mediate endomesoderm specification and primary archenteron invagination during gastrulation in Nematostella	7
Nociceptor subtypes are born continuously over DRG development	7
Kcnb1 plays a role in development of the inner ear	6
CARMIL3 is important for cell migration and morphogenesis during early development in zebrafish	6
Why study human embryo development?	6
Post-translational activation of Mmp2 correlates with patterns of active collagen degradation during the development of the zebrafish tail	6
A life cycle alteration can correct molting defects in Caenorhabditis elegans	6
Origin and diversification of fibroblasts from the sclerotome in zebrafish	6
Integrating animal development: How hormones and metabolism regulate developmental transitions and brain formation	6
mTOR plays a pivotal role in multiple processes of enamel organ development principally through the mTORC1 pathway and in part via regulating cytoskeleton dynamics	6
CFAP45, a heterotaxy and congenital heart disease gene, affects cilia stability	6
Mechanical role of actinotrichia in shaping the caudal fin of zebrafish	6
Cell polarity control by Wnt morphogens	6
Taste buds are not derived from neural crest in mouse, chicken, and zebrafish	6
Impact of cilia-related genes on mitochondrial dynamics during Drosophila spermatogenesis	6
Circadian clocks, retinogenesis and ocular health in vertebrates: new molecular insights	6
Lamprey lecticans link new vertebrate genes to the origin and elaboration of vertebrate tissues	6
When is a neuron like an epithelial cell	6
Transcriptional and epigenetic regulation of temporal patterning in neural progenitors	6
FMR1 loss in a human stem cell model reveals early changes to intrinsic membrane excitability	6
Interdependent regulation of stereotyped and stochastic photoreceptor fates in the fly eye	6
The multiple roles of caudal in early development of the milkweed bug Oncopeltus fasciatus	6
Fitness selection in human pluripotent stem cells and interspecies chimeras: Implications for human development and regenerative medicine	6
EXOSC10/Rrp6 is essential for the eight-cell embryo/morula transition	6
Early patterning of ABCB, ABCC, and ABCG transporters establishes unique territories of small molecule transport in embryonic mesoderm and endoderm	6
Analysis of lamprey meis genes reveals that conserved inputs from Hox, Meis and Pbx proteins control their expression in the hindbrain and neural tube	6
E3 ubiquitin ligase FBXW7 balances airway cell fates	6
Zeb2 regulates the balance between retinal interneurons and Müller glia by inhibition of BMP–Smad signaling	6
WNT5A-Ca2+-CaN-NFAT signalling plays a permissive role during cartilage differentiation in embryonic chick digit development	6
IRGC1, a testis-enriched immunity related GTPase, is important for fibrous sheath integrity and sperm motility in mice	6
Regulation of male fertility and accessory gland gene expression by the Drosophila HR39 nuclear receptor	6
Systemic racism, systemic sexism, and the embryological enterprise	6
Dermal EZH2 orchestrates dermal differentiation and epidermal proliferation during murine skin development	6
Yes-associated protein 1 translocation through actin cytoskeleton organization in trophectoderm cells	6
DDX24 is required for muscle fiber organization and the suppression of wound-induced Wnt activity necessary for pole re-establishment during planarian regeneration	6
The origin and evolution of gene targeting	5
Single cell transcriptomic analysis of external genitalia reveals complex and sexually dimorphic cell populations in the early genital tubercle	5
TurboID functions as an efficient biotin ligase for BioID applications in Xenopus embryos	5
Ethanol exposure perturbs sea urchin development and disrupts developmental timing	5
Cis-regulatory code for determining the action of Foxd as both an activator and a repressor in ascidian embryos	5
Transcriptome landscapes that signify Botrylloides leachi (Ascidiacea) torpor states	5
Serotonergic signaling plays a deeply conserved role in improving oocyte quality	5
Corpuscles of Stannius development requires FGF signaling	5
Cloning and characterisation of NMDA receptors in the Pacific oyster, Crassostrea gigas (Thunberg, 1793) in relation to metamorphosis and catecholamine synthesis	5
CDON contributes to Hedgehog-dependent patterning and growth of the developing limb	5
Cytoskeletal players in single-cell branching morphogenesis	5
Rab11 is essential to pancreas morphogenesis, lumen formation and endocrine mass	5
The morphogenetic changes that lead to cell extrusion in development and cell competition	5
The development of sex differences in the nervous system and behavior of flies, worms, and rodents	5
Regeneration among animals: An evolutionary hypothesis related to aquatic versus terrestrial environment	5
Transcriptional repression in stochastic gene expression, patterning, and cell fate specification	5
Planar cell polarity and the pathogenesis of Tourette Disorder: New hypotheses and perspectives	5
In vivo high-content imaging and regression analysis reveal non-cell autonomous functions of Shroom3 during neural tube closure	5
Expression atlas of avian neural crest proteins: Neurulation to migration	5
Protein kinase C family evolution in jawed vertebrates	5
Heterotrimeric Kinesin II is required for flagellar assembly and elongation of nuclear morphology during spermiogenesis in Schmidtea mediterranea	5