Computers in Biology and Medicine

Article	Citations
Gene-related Parkinson's disease diagnosis via feature-based multi-branch octave convolution network	740
Electroanatomical mapping of the stomach with simultaneous biomagnetic measurements	396
Dynamic topography analysis of the cornea and its application to the diagnosis of keratoconus	354
Editorial Board	315
Vectorial-based analysis of dual-tracer PET imaging: A proof of concept	272
A general sample-weighted framework for epileptic seizure prediction	270
A Three-branch Jointed Feature and Topology Decoder guided by game-theoretic interactions for temporomandibular joint segmentation	268
Context encoder transfer learning approaches for retinal image analysis	252
Editorial Board	247
Computer models evaluating hand tremors in Parkinson's disease patients	235
Automatic segmentation of intraluminal thrombosis of abdominal aortic aneurysms from CT angiography using a mixed-scale-driven multiview perception network (M2Net) model	217
Identification of anti-cancer organometallic compounds by inhibition of BCL-2/Bax interactions	217
Screening of potent phytochemical inhibitors against SARS-CoV-2 protease and its two Asian mutants	216
Functional identification and prediction of lncRNAs in esophageal cancer	203
Diffuse tumors: Molecular determinants shared by different cancer types	203
Artificial intelligence for identification of candidates for device-aided therapy in Parkinson's disease: DELIST-PD study	202
Counting on AR: EEG responses to incongruent information with real-world context	195
AGNet: Automatic generation network for skin imaging reports	192
EpiTEAmDNA: Sequence feature representation via transfer learning and ensemble learning for identifying multiple DNA epigenetic modification types across species	191
Assessing clinical utility of machine learning and artificial intelligence approaches to analyze speech recordings in multiple sclerosis: A pilot study	179
Integrating biocomputational techniques for Breast cancer drug discovery via the HER-2, BCRA, VEGF and ER protein targets	177
The role of the extracellular matrix in the reduction of lateral force transmission in muscle bundles: A finite element analysis	171
Fine-grained food image classification and recipe extraction using a customized deep neural network and NLP	170
Data-driven discovery of sparse dynamical model of cardiovascular system for model predictive control	168
Artificial vascular image generation using blood vessel texture maps	165

Identifying indications for novel drugs using electronic health records	165
Molecular modelling and experimental validation identified a new therapeutic inhibitor of toxoplasmosis	164
Hybrid offline and self-knowledge distillation for acute ischemic stroke lesion segmentation from non-contrast CT scans	155
Carotid single- and dual-layer stents reduce the wall adhesion of platelets by influencing flow and cellular transport	154
Identification of JUN as determinant of osteoarthritis and its inhibition by the Chinese herbal formulae Zhuanggu Huoxue Tang	151
Pathogenicity classification of missense mutations based on deep generative model	147
Eye movement analysis for real-world settings using segmented linear regression	146
Triage and monitoring of COVID-19 patients in intensive care using unsupervised machine learning	138
Pedicle drilling force control of a robotic surgical system via spine-soft tissue coupling model and parameters optimization	138
A partially shared joint clustering framework for detecting protein complexes from multiple state-specific signed interaction networks	137
S2FLNet: Hepatic steatosis detection network with body shape	135
Automated identification of patient subgroups: A case-study on mortality of COVID-19 patients admitted to the ICU	133
HOTGpred: Enhancing human O-linked threonine glycosylation prediction using integrated pretrained protein language model-based features and multi-stage feature selection approach	133
Contrastive learning based method for X-ray and CT registration under surgical equipment occlusion	131
Quantitative computed tomography imaging-based classification of cement dust-exposed subjects with an artificial neural network technique	129
Enhancing targeted tumor treatment: A novel fuzzy logic framework for precision drug delivery strategy selection	128
A computational model of the effects of macronutrients absorption and physical exercise on hormonal regulation and metabolic homeostasis	126
A self-supervised COVID-19 CT recognition system with multiple regularizations	125
Visual prior-based cross-modal alignment network for radiology report generation	125
Prediction of protein N-terminal acetylation modification sites based on CNN-BiLSTM-attention model	124
Automated mitral inflow Doppler peak velocity measurement using deep learning	123
Context-aggregator: An approach of loss- and class imbalance-aware aggregation in federated learning	123
Red blood cell passage through deformable interendothelial slits in the spleen: Insights into splenic filtration and hemodynamics	123
Adaptive nonlinear filtering algorithms for removal of non-stationary noise in electronystagmographic signals	122
Analysis of COVID-19 pandemic in USA, using Topological Weighted Centroid	122
Classical Simulations on Quantum Computers: Interface-Driven Peptide Folding on Simulated Membrane Surfaces	122
Graph neural network-based subgraph analysis for predicting adverse drug events	121
Multiscale differential geometry learning of networks with applications to single-cell RNA sequencing data	121
Improved predictive diagnosis of diabetic macular edema based on hybrid models: An observational study	120
Non-same-scale feature attention network based on BPD for medical image segmentation	119
An efficient model for extracting respiratory and blood oxygen saturation data from photoplethysmogram signals by removing motion artifacts using heuristic-aided ensemble learning model	119
Unraveling the complexities of pathological voice through saliency analysis	119
Insights from explainable AI in oesophageal cancer team decisions	119
Class-Specific Distribution Alignment for semi-supervised medical image classification	118
Discrete element method-based simulation system for predicting natural stone evacuation pathways in patients with urolithiasis	117
Reversing skin cancer adversarial examples by multiscale diffusive and denoising aggregation mechanism	117
Evaluation of the mechanical behaviour of the expandable wedge locked nail fixation in retrograde use: A finite element study	116
A novel mobile phone and tablet application for automatized calculation of pain extent	113
Two-stage error detection to improve electron microscopy image mosaicking	112
A hybrid methodology for breast screening and cancer diagnosis using thermography	110
FCSU-Net: A novel full-scale Cross-dimension Self-attention U-Net with collaborative fusion of multi-scale feature for medical image segmentation	110
Enhanced depression detection from speech using Quantum Whale Optimization Algorithm for feature selection	109
A method for predicting linear and conformational B-cell epitopes in an antigen from its primary sequence	108
An improved RIME optimization algorithm for lung cancer image segmentation	107
CauDR: A causality-inspired domain generalization framework for fundus-based diabetic retinopathy grading	107
Mapping synthetic binding proteins epitopes on diverse protein targets by protein structure prediction and protein-protein docking	106
Multi-constraint point set registration with redundant point removal for the registration of coronary arteries	105
A unique view of SARS-CoV-2 through the lens of ORF8 protein	105
Dual-Stream Subspace Clustering Network for revealing gene targets in Alzheimer's disease	103
Towards a better understanding of TF-DNA binding prediction from genomic features	102

SURVS: A Swin-Unet and game theory-based unsupervised segmentation method for retinal vessel	102
Linear and nonlinear analysis of intrinsic mode function after facial stimuli presentation in children with autism spectrum disorder	101
Deep-learning-based real-time individualization for reduce-order haemodynamic model	101
CARES: A Corpus for classification of Spanish Radiological reports	101
Automated tool detection with deep learning for monitoring kinematics and eye-hand coordination in microsurgery	101
Conditional GAN based augmentation for predictive modeling of respiratory signals	100
Multi-label classification of fundus images with graph convolutional network and LightGBM	100
Prediction of lung cancer metastasis by gene expression	100
Potential inhibitors of the main protease of SARS-CoV-2 and modulators of arachidonic acid pathway: Non-steroidal anti-inflammatory drugs against COVID-19	100
A systematic review on the state-of-the-art strategies for protein representation	99
ILSHIP: An interpretable and predictive model for hypothyroidism	99
DrugormerDTI: Drug Graphormer for drug–target interaction prediction	99
Hierarchical cumulative network for unsupervised medical image registration	99
Development and validation of a neutrophil extracellular traps-related gene signature for lower-grade gliomas	98
REDDA: Integrating multiple biological relations to heterogeneous graph neural network for drug-disease association prediction	98
Blood glucose detection based on Teager-Kaiser main energy of photoacoustic signal	98
Causal relationship between slow waves of arterial, intracranial pressures and blood velocity in brain	97
LSDVvac: An immunoinformatics database for vaccine design against lumpy skin disease virus	96
Enhancing cell instance segmentation in scanning electron microscopy images via a deep contour closing operator	96
Semi-empirical Anticoagulation Model (SAM): Dose prediction during warfarin therapy	96
Synergistic eigenanalysis of covariance and Hessian matrices for enhanced binary classification on health datasets	95
In silico evaluation of lattice designs for additively manufactured total hip implants	94
Wearable-based human flow experience recognition enhanced by transfer learning methods using emotion data	94
Identifying fetal status with fetal heart rate: Deep learning approach based on long convolution	94
Identification of lncRNA associated with the SERPINE1 gene in colorectal cancer through TGF-β pathway	93
Drug repurposing of triazoles against mucormycosis using molecular docking: A short communication	93
Single-channel EEG based insomnia detection with domain adaptation	92
Personalized brachytherapy dose reconstruction using deep learning	92
A deep learning based model using RNN-LSTM for the Detection of Schizophrenia from EEG data	92
Simulated annealing aided genetic algorithm for gene selection from microarray data	91
Performance optimization of differential evolution with slime mould algorithm for multilevel breast cancer image segmentation	91
Deep learning and machine learning approaches to classify stomach distant metastatic tumors using DNA methylation profiles	90
Hemodynamic alternations following stent deployment and post-dilation in a heavily calcified coronary artery: In silico and ex-vivo approaches	90
Structure-based design of promising natural products to inhibit thymidylate kinase from Monkeypox virus and validation using free energy calculations	90
Prostate158 - An expert-annotated 3T MRI dataset and algorithm for prostate cancer detection	89
DRBpred: A sequence-based machine learning method to effectively predict DNA- and RNA-binding residues	88
How CLSPN could demystify its prognostic value and potential molecular mechanism for hepatocellular carcinoma: A crosstalk study	88
A mask R-CNN based automatic assessment system for nail psoriasis severity	87
AELGNet: Attention-based Enhanced Local and Global Features Network for medicinal leaf and plant classification	87
MCA-net: A multi-task channel attention network for Myocardial infarction detection and location using 12-lead ECGs	86
Effect of tumor heterogeneity on enhancing drug delivery to vascularized tumors using thermo-sensitive liposomes triggered by hyperthermia: A multi-scale and multi-physics computational model	86
Automatic eczema classification in clinical images based on hybrid deep neural network	84
KNU-DTI: KNowledge United Drug-Target Interaction prediction	84
IVD fibrosis and disc collapse comprehensively aggravate vertebral body disuse osteoporosis and zygapophyseal joint osteoarthritis by posteriorly shifting the load transmission pattern	84
JoCoRank: Joint correlation learning with ranking similarity regularization for imbalanced fetal brain age regression	84
Discrepancy-based diffusion models for lesion detection in brain MRI	84
Quantifying the influence of combined lung and kidney support using a cardiovascular model and sensitivity analysis-informed parameter identification	83
Corrigendum to “Unraveling the molecular landscape of non-small cell lung cancer: Integrating bioinformatics and statistical approaches to identify biomarkers and drug repurposing” [Comput. Biol. Med.	83
AIScholar: An OpenFaaS-enhanced cloud platform for intelligent medical data analytics	83
Disclosing neonatal pain in real-time: AI-derived pain sign from continuous assessment of facial expressions	83
Dynamic Statistical Attention-based lightweight model for Retinal Vessel Segmentation: DyStA-RetNet	83
Editorial Board	83
A novel hybrid ViT-LSTM model with explainable AI for brain stroke detection and classification in CT images: A case study of Rajshahi region	82
Detecting IDH and TERTp mutations in diffuse gliomas using 1H-MRS with attention deep-shallow networks	82
D-glucose-conjugated thioureas containing 2-aminopyrimidine as potential multitarget inhibitors for type 2 diabetes mellitus: Synthesis and biological activity study	82
DE-JANet: A unified network based on dual encoder and joint attention for Alzheimer’s disease classification using multi-modal data	81
A review of deep learning-based information fusion techniques for multimodal medical image classification	81
COVID-19 diagnosis using state-of-the-art CNN architecture features and Bayesian Optimization	81
An efficient image segmentation method for skin cancer imaging using improved golden jackal optimization algorithm	81
Pharmacophore-guided computational modeling of quinolone-ATPase conjugate inhibitors targeting DNA GyrB subunit of Staphylococcus aureus	81
Development of closed-loop modelling framework for adaptive respiratory pacemakers	80
MulStack: An ensemble learning prediction model of multilabel mRNA subcellular localization	80
Predicting lung cancer survival based on clinical data using machine learning: A review	80
A YOLO based software for automated detection and analysis of rodent behaviour in the open field arena	79
Predictive modeling for early detection of biliary atresia in infants with cholestasis: Insights from a machine learning study	79
A comprehensive analysis of single-cell RNA transcriptome reveals unique SPP1+ chondrocytes in human osteoarthritis	79
The role and potential of computer-aided drug discovery strategies in the discovery of novel antimicrobials	79
Thyroid region prior guided attention for ultrasound segmentation of thyroid nodules	78
Uniqueness of inspiratory airflow patterns in a realistic rat nasal cavity	78
Artificial intelligence techniques for prediction of drug synergy in malignant diseases: Past, present, and future	77
Insights into potential mechanisms of asthma patients with COVID-19: A study based on the gene expression profiling of bronchoalveolar lavage fluid	77
GasHisSDB: A new gastric histopathology image dataset for computer aided diagnosis of gastric cancer	77
Extinction and stationary distribution of a stochastic COVID-19 epidemic model with time-delay	77
The role of mechano-electric feedbacks and hemodynamic coupling in scar-related ventricular tachycardia	77
You get the best of both worlds? Integrating deep learning and traditional machine learning for breast cancer risk prediction	76
Computational prediction of protein folding rate using structural parameters and network centrality measures	76
Temporal relative transformer encoding cooperating with channel attention for EEG emotion analysis	76
Analysis of domain shift in whole prostate gland, zonal and lesions segmentation and detection, using multicentric retrospective data	76
Sparse Dynamic Volume TransUNet with multi-level edge fusion for brain tumor segmentation	75
Drug repositioning for rosacea disease: Biological TARGET identification, molecular docking, pharmacophore mapping, and molecular dynamics analysis	75

Prediction of colorectal cancer based on taxonomic levels of microorganisms and discovery of taxonomic biomarkers using the Grouping-Scoring-Modeling (G-S-M) approach	75
Mass diffusion in multi-layer systems: an electrical analogue modelling approach	75
Estimation of BMI from facial images using semantic segmentation based region-aware pooling	74
Identification of potential agonist-like molecules for α2-adrenergic receptor by multi-layer virtual screening to combat sinusitis	74
Novel ensemble of optimized CNN and dynamic selection techniques for accurate Covid-19 screening using chest CT images	74
Stack-AAgP: Computational prediction and interpretation of anti-angiogenic peptides using a meta-learning framework	74
Integrating CNN and Bi-LSTM for protein succinylation sites prediction based on Natural Language Processing technique	73
Emotion recognition in EEG signals using deep learning methods: A review	73
A robust drug recall supply chain management system using hyperledger blockchain ecosystem	73
A transformer-based deep neural network for arrhythmia detection using continuous ECG signals	73
Identification of molecular and cellular infection response biomarkers associated with anthrax infection through comparative analysis of gene expression data	72
Transcriptome analysis displays new molecular insights into the mechanisms of action of Mebendazole in gastric cancer cells	72
Performance of multilabel machine learning models and risk stratification schemas for predicting stroke and bleeding risk in patients with non-valvular atrial fibrillation	72
Dynamic modeling of antibody repertoire reshaping in response to viral infections	72
Molecular hybridization assisted multi-technique approach for designing USP21 inhibitors to halt catalytic triad-mediated nucleophilic attack and suppress pancreatic ductal adenocarcinoma progression:	71
An efficient cardiovascular disease prediction model through AI-driven IoT technology	71
Exploring molecular mechanisms of diazinon toxicity in HT22 hippocampal neurons through integrated miRNA and mRNA profiling	71
Role of [18F]-PSMA-1007 PET radiomics for seminal vesicle invasion prediction in primary prostate cancer	71
Lupus nephritis diagnosis using enhanced moth flame algorithm with support vector machines	70
Torque modulation mechanism of the knee joint during balance recovery	70
Hierarchical Harris hawks optimization for epileptic seizure classification	70
Computational Traditional Chinese Medicine diagnosis: A literature survey	70
CFD simulations of inhalation through a subject-specific human larynx – Impact of the unilateral vocal fold immobility	70
Deep networks for behavioral variant frontotemporal dementia identification from multiple acquisition sources	70
A mechanobiological model for tumor spheroid evolution with application to glioblastoma: A continuum multiphysics approach	69
Effective fall detection and post-fall breath rate tracking using a low-cost CW Doppler radar sensor	69
Identification of telomere-associated gene signatures to predict prognosis and drug sensitivity in glioma	69
A novel compartmental model to capture the nonlinear trend of COVID-19	69
Semi-automatic vessel detection for challenging cases of peripheral arterial disease	69
Genomic instability-related twelve-microRNA signatures for predicting the prognosis of gastric cancer	68
PrimePatNet87: Prime pattern and tunable q-factor wavelet transform techniques for automated accurate EEG emotion recognition	68
A robust time delay estimation method for ultrasonic echo signals and elastography	68
Computer modeling of radiofrequency cardiac ablation including heartbeat-induced electrode displacement	68
An unsupervised image registration method employing chest computed tomography images and deep neural networks	67
Automatic bone maturity grading from EOS radiographs in Adolescent Idiopathic Scoliosis	66
Microscopic dynamics modeling unravels the role of asymptomatic virus carriers in SARS-CoV-2 epidemics at the interplay between biological and social factors	66
Collaborative networks of transformers and convolutional neural networks are powerful and versatile learners for accurate 3D medical image segmentation	66
Intelligent tuberculosis activity assessment system based on an ensemble of neural networks	65
Impact of physiological loads of arterial wall on nucleus deformation in endothelial cells: A computational study	65
Smoke veil prior regularized surgical field desmoking without paired in-vivo data	65
The detection of mild traumatic brain injury in paediatrics using artificial neural networks	65
Multi-scale, multi-dimensional binocular endoscopic image depth estimation network	65
Attention2Minority: A salient instance inference-based multiple instance learning for classifying small lesions in whole slide images	65
A computational framework to simulate the thermochemical process during thermochemical ablation of biological tissues	65
A conversational agent for querying Italian Patient Information Leaflets and improving health literacy	64
Design and hierarchical analysis of magnetic actuated robot: A governing equation based approach	64
Interplay of mutations, alternate mechanisms, and treatment breaks in leukaemia: Understanding and implications studied with stochastic models	64
PNMC: Four-dimensional conebeam CT reconstruction combining prior network and motion compensation	64
Directed Graph Mapping exceeds Phase Mapping for the detection of simulated 2D meandering rotors in fibrotic tissue with added noise	64
Analysis and design of antithetic proportional-integral-derivative biocontrol-systems with species dilution	64
Validation of fluid-structure interaction simulations of the opening phase of phantom mitral heart valves under physiologically inspired conditions	64
PEA-Net: A progressive edge information aggregation network for vessel segmentation	63
Impact of workflow variability on image-based intracranial aneurysm hemodynamics	63
Privacy preserving distributed learning classifiers – Sequential learning with small sets of data	63
SNN6mA: Improved DNA N6-methyladenine site prediction using Siamese network-based feature embedding	63
FIM: A fatigued-injured muscle model based on the sliding filament theory	63
Novel classification of brain vascular tortuosity measures: A systematic review	62
SLT-Net: A codec network for skin lesion segmentation	62
Breast cancer detection and classification: A study on the specification and implementation of multilayer perceptron analog artificial neural networks	62
An adaptive language model-based intelligent medication assistant for the decision support of antidepressant prescriptions	62
A sleep staging model on wavelet-based adaptive spectrogram reconstruction and light weight CNN	62
Efficient parallel simulation of hemodynamics in patient-specific abdominal aorta with aneurysm	60
A multi-granularity convolutional neural network model with temporal information and attention mechanism for efficient diabetes medical cost prediction	60
Potential anti-liver cancer targets and mechanisms of kaempferitrin based on network pharmacology, molecular docking and experimental verification	60
Sterenin M as a potential inhibitor of SARS-CoV-2 main protease identified from MeFSAT database using molecular docking, molecular dynamics simulation and binding free energy calculation	60
Energy consumption during insect flight and bioinspiration for MAV design: A review	60
Multilevel threshold image segmentation for COVID-19 chest radiography: A framework using horizontal and vertical multiverse optimization	60
Structural and functional analysis of disease-associated mutations in GOT1 gene: An in silico study	60
ACP-MLC: A two-level prediction engine for identification of anticancer peptides and multi-label classification of their functional types	59
Ce	59
Extensive T1-weighted MRI preprocessing improves generalizability of deep brain age prediction models	59
Enhanced single-cell RNA-seq embedding through gene expression and data-driven gene-gene interaction integration	59
Identification of a novel gene signature for the prognosis of sepsis	59
Characterizing patients at higher cardiovascular risk for prescribed stimulants: Learning from health records data with predictive analytics and data mining techniques	59
Computational identification of repurposed drugs against viruses causing epidemics and pandemics via drug-target network analysis	59
Editorial Board	58
A novel multi-objective metaheuristic algorithm for protein-peptide docking and benchmarking on the LEADS-PEP dataset	58
Cross attention guided multi-scale feature fusion for false-positive reduction in pulmonary nodule detection	58
A computational optimization study of a self-expandable transcatheter aortic valve	58
Cancer-inspired genomics mapper model for the generation of synthetic DNA sequences with desired genomics signatures	57
SPMLD: A skin pathological image dataset for non-melanoma with detailed lesion area annotation	57
Application of noise-reduction techniques to machine learning algorithms for breast cancer tumor identification	57
Wearable multisource quantitative gait analysis of Parkinson's diseases	57
A bidirectional registration neural network for cardiac motion tracking using cine MRI images	57
Alcohol patch test with hue-saturation-value model analysis predicts ALDH2 genetic polymorphism	56
Prediction of drug-target interactions via neural tangent kernel extraction feature matrix factorization model	56
Joint cardiac tissue conductivity and activation time estimation using confirmatory factor analysis	56
Bone marrow sparing oriented multi-model image registration in cervical cancer radiotherapy	56
Computationally efficient model to predict the deformations of a cellular foot orthotic	56
Enclosing 95% confidence area and volume to center of pressure and center of mass in posturography using optimization algorithm and coordinate ascent methods	55
Conformational transformation of switch domains in GDP/K-Ras induced by G13 mutants: An investigation through Gaussian accelerated molecular dynamics simulations and principal component analysis	55
Genetic algorithm based image reconstruction applying the digital holography process with the Discrete Orthonormal Stockwell Transform technique for diagnosis of COVID-19	55
A wrapper method for finding optimal subset of multimodal Magnetic Resonance Imaging sequences for ischemic stroke lesion segmentation	55
A novel mTOR-associated gene signature for predicting prognosis and evaluating tumor immune microenvironment in lung adenocarcinoma	55
Three-dimensional morphology scoring of hepatocellular carcinoma stratifies prognosis and immune infiltration	54