Computers in Biology and Medicine

Article	Citations
Editorial Board	431
Beyond accuracy: The need for explainable AI in biomedical voice technology	376
Discrepancy-based diffusion models for lesion detection in brain MRI	374
Identifying indications for novel drugs using electronic health records	322
Carotid single- and dual-layer stents reduce the wall adhesion of platelets by influencing flow and cellular transport	320
Eye movement analysis for real-world settings using segmented linear regression	318
Advances in disease detection through retinal imaging: A systematic review	311
Anemia prediction using gene expression programming (GEP) and explainable artificial intelligence approaches	310
Classical Simulations on Quantum Computers: Interface-Driven Peptide Folding on Simulated Membrane Surfaces	304
Identification of anti-cancer organometallic compounds by inhibition of BCL-2/Bax interactions	303
Numerical analysis of coil designs to expedite fracture healing using dielectrophoresis with S method	284
Automated mitral valve segmentation in PLAX-view transthoracic echocardiography for anatomical assessment and risk stratification	282
LSDVvac: An immunoinformatics database for vaccine design against lumpy skin disease virus	255
DRBpred: A sequence-based machine learning method to effectively predict DNA- and RNA-binding residues	254
Discrete element method-based simulation system for predicting natural stone evacuation pathways in patients with urolithiasis	246
Deep learning and machine learning approaches to classify stomach distant metastatic tumors using DNA methylation profiles	226
Automated mitral inflow Doppler peak velocity measurement using deep learning	217
KS-TMIL: A K-Stage Transformer approach with multiple instance learning model for ovarian cancer subtype classification	202
M3-Net++: A multi-scale, multi-level, multi-stream network for nuclei segmentation in breast cancer histopathology using hierarchical context extraction and hybrid loss optimization	198
Automated identification of patient subgroups: A case-study on mortality of COVID-19 patients admitted to the ICU	195
A novel mobile phone and tablet application for automatized calculation of pain extent	194
Vectorial-based analysis of dual-tracer PET imaging: A proof of concept	194
Dynamic topography analysis of the cornea and its application to the diagnosis of keratoconus	191
A computational model of the effects of macronutrients absorption and physical exercise on hormonal regulation and metabolic homeostasis	181
Editorial Board	173

Functional identification and prediction of lncRNAs in esophageal cancer	172
Evaluation of the mechanical behaviour of the expandable wedge locked nail fixation in retrograde use: A finite element study	166
Electroanatomical mapping of the stomach with simultaneous biomagnetic measurements	166
Artificial vascular image generation using blood vessel texture maps	164
Drug repositioning for rosacea disease: Biological TARGET identification, molecular docking, pharmacophore mapping, and molecular dynamics analysis	163
Towards a better understanding of TF-DNA binding prediction from genomic features	162
Uniqueness of inspiratory airflow patterns in a realistic rat nasal cavity	157
Eudesma-4(15), 7-dien-1-β-ol, A promising natural drug candidate for Alzheimer's disease targeting the NMDA pathway: GC-MS identification, molecular docking, pharmacokinetic and molecular dynamic anal	151
A self-supervised COVID-19 CT recognition system with multiple regularizations	151
Data-driven discovery of sparse dynamical model of cardiovascular system for model predictive control	148
AGNet: Automatic generation network for skin imaging reports	147
Multiscale differential geometry learning of networks with applications to single-cell RNA sequencing data	147
Deriving a suitable schedule through robust H	145
Extinction and stationary distribution of a stochastic COVID-19 epidemic model with time-delay	142
ILSHIP: An interpretable and predictive model for hypothyroidism	142
Identifying fetal status with fetal heart rate: Deep learning approach based on long convolution	141
FCSU-Net: A novel full-scale Cross-dimension Self-attention U-Net with collaborative fusion of multi-scale feature for medical image segmentation	139
A method for predicting linear and conformational B-cell epitopes in an antigen from its primary sequence	137
Graph neural network-based subgraph analysis for predicting adverse drug events	136
Two-stage error detection to improve electron microscopy image mosaicking	135
Prediction of colorectal cancer based on taxonomic levels of microorganisms and discovery of taxonomic biomarkers using the Grouping-Scoring-Modeling (G-S-M) approach	134
Corrigendum to “Unraveling the molecular landscape of non-small cell lung cancer: Integrating bioinformatics and statistical approaches to identify biomarkers and drug repurposing” [Comput. Biol. Med.	134
Editorial Board	134
Disclosing neonatal pain in real-time: AI-derived pain sign from continuous assessment of facial expressions	133
AIScholar: An OpenFaaS-enhanced cloud platform for intelligent medical data analytics	133
Semi-empirical Anticoagulation Model (SAM): Dose prediction during warfarin therapy	130
Deep-learning-based real-time individualization for reduce-order haemodynamic model	129
Identifying potent natural inhibitors of the hepatitis C virus NS3 protein using multiple computational and molecular approaches	129
Analysis of domain shift in whole prostate gland, zonal and lesions segmentation and detection, using multicentric retrospective data	129
CARES: A Corpus for classification of Spanish Radiological reports	129
Synergistic eigenanalysis of covariance and Hessian matrices for enhanced binary classification on health datasets	128
Context encoder transfer learning approaches for retinal image analysis	126
Multi-constraint point set registration with redundant point removal for the registration of coronary arteries	125
DeepSMR: Decoding high-complex motor imagery via subject-dependent multi-feature refinement in deep convolutional networks	123
A partially shared joint clustering framework for detecting protein complexes from multiple state-specific signed interaction networks	122
Dual-Stream Subspace Clustering Network for revealing gene targets in Alzheimer's disease	121
Gene-related Parkinson's disease diagnosis via feature-based multi-branch octave convolution network	120
ST-SRPerf: Continuous spatiotemporal representation for perfusion MRI super-resolution through neural ODE and implicit neural representation	120
Automatic eczema classification in clinical images based on hybrid deep neural network	120
Insights into potential mechanisms of asthma patients with COVID-19: A study based on the gene expression profiling of bronchoalveolar lavage fluid	120
Wearable-based human flow experience recognition enhanced by transfer learning methods using emotion data	119
Revised NMS-driven pipeline for heart valve regurgitation and Kawasaki disease coronary aneurysm localization	118
D-glucose-conjugated thioureas containing 2-aminopyrimidine as potential multitarget inhibitors for type 2 diabetes mellitus: Synthesis and biological activity study	118
Optimization of deep learning models for inference in low resource environments	115
KC-UNIT: Multi-kernel conversion using unpaired image-to-image translation with perceptual guidance in chest computed tomography imaging	115
Enhancing cell instance segmentation in scanning electron microscopy images via a deep contour closing operator	115
Computational prediction of protein folding rate using structural parameters and network centrality measures	114
Artificial intelligence techniques for prediction of drug synergy in malignant diseases: Past, present, and future	113
Reversing skin cancer adversarial examples by multiscale diffusive and denoising aggregation mechanism	112
SSMT-PANBERT: A single-stage multitask model for phenotype extraction and assertion negation detection in unstructured clinical text	112

Performance of multilabel machine learning models and risk stratification schemas for predicting stroke and bleeding risk in patients with non-valvular atrial fibrillation	111
Hybrid offline and self-knowledge distillation for acute ischemic stroke lesion segmentation from non-contrast CT scans	110
Longitudinal dementia trajectories for Alzheimer’s Disease characterization and prediction	108
Enhancing targeted tumor treatment: A novel fuzzy logic framework for precision drug delivery strategy selection	106
Pedicle drilling force control of a robotic surgical system via spine-soft tissue coupling model and parameters optimization	104
Adaptive nonlinear filtering algorithms for removal of non-stationary noise in electronystagmographic signals	103
Pathogenicity classification of missense mutations based on deep generative model	103
KNU-DTI: KNowledge United Drug-Target Interaction prediction	102
CauDR: A causality-inspired domain generalization framework for fundus-based diabetic retinopathy grading	101
Modelling of thrombus formation, growth and embolisation in the left atrial appendage under atrial fibrillation	101
A mask R-CNN based automatic assessment system for nail psoriasis severity	99
Quantitative computed tomography imaging-based classification of cement dust-exposed subjects with an artificial neural network technique	99
Exploring the spike glycoprotein-encoding gene of SARS-CoV-2 using multifractal analysis: Unveiling structural complexity and implications for viral transmission	97
A novel hybrid ViT-LSTM model with explainable AI for brain stroke detection and classification in CT images: A case study of Rajshahi region	97
Identification of potential agonist-like molecules for α2-adrenergic receptor by multi-layer virtual screening to combat sinusitis	96
Unraveling the complexities of pathological voice through saliency analysis	95
EpiTEAmDNA: Sequence feature representation via transfer learning and ensemble learning for identifying multiple DNA epigenetic modification types across species	93
Stack-AAgP: Computational prediction and interpretation of anti-angiogenic peptides using a meta-learning framework	92
Identification of JUN as determinant of osteoarthritis and its inhibition by the Chinese herbal formulae Zhuanggu Huoxue Tang	92
Explainable AI-driven prediction of influenza neuraminidase inhibitors using a stacked ensemble-learning framework	91
Improved predictive diagnosis of diabetic macular edema based on hybrid models: An observational study	91
JoCoRank: Joint correlation learning with ranking similarity regularization for imbalanced fetal brain age regression	91
DE-JANet: A unified network based on dual encoder and joint attention for Alzheimer’s disease classification using multi-modal data	90
Mapping synthetic binding proteins epitopes on diverse protein targets by protein structure prediction and protein-protein docking	90
Prediction of protein N-terminal acetylation modification sites based on CNN-BiLSTM-attention model	89
The role of the extracellular matrix in the reduction of lateral force transmission in muscle bundles: A finite element analysis	88
Red blood cell passage through deformable interendothelial slits in the spleen: Insights into splenic filtration and hemodynamics	88
Prostate158 - An expert-annotated 3T MRI dataset and algorithm for prostate cancer detection	87
Enhancing and advancements in deep learning for melanoma detection: A comprehensive review	87
A general sample-weighted framework for epileptic seizure prediction	87
Dynamical pattern of successive bits to predict the outcomes of the SSRI and rTMS depression therapies using EEG signals	86
A Three-branch Jointed Feature and Topology Decoder guided by game-theoretic interactions for temporomandibular joint segmentation	86
Deep learning-based feature discovery for decoding phenotypic plasticity in pediatric high-grade gliomas single-cell transcriptomics	86
Structure, sensing and control of pneumatic upper limb rehabilitation system: Review and prospect	86
A robust drug recall supply chain management system using hyperledger blockchain ecosystem	84
An efficient model for extracting respiratory and blood oxygen saturation data from photoplethysmogram signals by removing motion artifacts using heuristic-aided ensemble learning model	84
Computer models evaluating hand tremors in Parkinson's disease patients	84
Diffuse tumors: Molecular determinants shared by different cancer types	84
In silico evaluation of lattice designs for additively manufactured total hip implants	83
S2FLNet: Hepatic steatosis detection network with body shape	83
AI-based bi-modal fusion system for automated clinical pain monitoring	83
A computational study of venom as drug library: Discovery of multifunctional astacin-like metalloproteases from Androctonus zagrosensis venom gland transcriptome	83
Development of closed-loop modelling framework for adaptive respiratory pacemakers	82
A transformer-based deep neural network for arrhythmia detection using continuous ECG signals	82
Insights from explainable AI in oesophageal cancer team decisions	82
Context-aggregator: An approach of loss- and class imbalance-aware aggregation in federated learning	81
Fine-grained food image classification and recipe extraction using a customized deep neural network and NLP	81
Integrating biocomputational techniques for Breast cancer drug discovery via the HER-2, BCRA, VEGF and ER protein targets	81
Predictive modeling for early detection of biliary atresia in infants with cholestasis: Insights from a machine learning study	81
Bayesian parameter inference and uncertainty-informed sensitivity analysis in a 0D cardiovascular model for intraoperative hypotension	81
Quantifying the influence of combined lung and kidney support using a cardiovascular model and sensitivity analysis-informed parameter identification	80
Effect of tumor heterogeneity on enhancing drug delivery to vascularized tumors using thermo-sensitive liposomes triggered by hyperthermia: A multi-scale and multi-physics computational model	80
A systematic review on the state-of-the-art strategies for protein representation	80
Predicting lung cancer survival based on clinical data using machine learning: A review	79
Non-same-scale feature attention network based on BPD for medical image segmentation	79
Artificial intelligence for identification of candidates for device-aided therapy in Parkinson's disease: DELIST-PD study	78
Integrating CNN and Bi-LSTM for protein succinylation sites prediction based on Natural Language Processing technique	78
Automatic segmentation of intraluminal thrombosis of abdominal aortic aneurysms from CT angiography using a mixed-scale-driven multiview perception network (M2Net) model	78
Efficient sleep apnea detection using single-lead ECG: A CNN-Transformer-LSTM approach	78
Optimizing multimodal models for medical visual question answering: A comparative study of LoRA and AdaLoRA on VQA-RAD and SLAKE-VQA	78
Prediction of lung cancer metastasis by gene expression	77
Assessing clinical utility of machine learning and artificial intelligence approaches to analyze speech recordings in multiple sclerosis: A pilot study	77
MOIS-SAM2: Exemplar-based segment anything model 2 for multi-lesion interactive segmentation of neurofibromas in whole-body MRI	77
SURVS: A Swin-Unet and game theory-based unsupervised segmentation method for retinal vessel	76
Pharmacophore-guided computational modeling of quinolone-ATPase conjugate inhibitors targeting DNA GyrB subunit of Staphylococcus aureus	76
AELGNet: Attention-based Enhanced Local and Global Features Network for medicinal leaf and plant classification	75
Development and validation of a neutrophil extracellular traps-related gene signature for lower-grade gliomas	75
Identification of lncRNA associated with the SERPINE1 gene in colorectal cancer through TGF-β pathway	75
HOTGpred: Enhancing human O-linked threonine glycosylation prediction using integrated pretrained protein language model-based features and multi-stage feature selection approach	73
How CLSPN could demystify its prognostic value and potential molecular mechanism for hepatocellular carcinoma: A crosstalk study	73
A deep learning model combining convolutional neural networks and a selective kernel mechanism for SSVEP-Based BCIs	73
Class-Specific Distribution Alignment for semi-supervised medical image classification	73
COVID-19 diagnosis using state-of-the-art CNN architecture features and Bayesian Optimization	72
GasHisSDB: A new gastric histopathology image dataset for computer aided diagnosis of gastric cancer	72
You get the best of both worlds? Integrating deep learning and traditional machine learning for breast cancer risk prediction	72
A novel Harris Hawks Optimization-based clustering method for elucidating genetic associations in osteoarthritis and Diverse Cancer Types	72
Temporal relative transformer encoding cooperating with channel attention for EEG emotion analysis	72
MulStack: An ensemble learning prediction model of multilabel mRNA subcellular localization	71
Simulated annealing aided genetic algorithm for gene selection from microarray data	71
Detecting IDH and TERTp mutations in diffuse gliomas using 1H-MRS with attention deep-shallow networks	70

Counting on AR: EEG responses to incongruent information with real-world context	70
Dynamic Statistical Attention-based lightweight model for Retinal Vessel Segmentation: DyStA-RetNet	70
Sparse Dynamic Volume TransUNet with multi-level edge fusion for brain tumor segmentation	70
Enhanced depression detection from speech using Quantum Whale Optimization Algorithm for feature selection	70
An improved RIME optimization algorithm for lung cancer image segmentation	70
Triage and monitoring of COVID-19 patients in intensive care using unsupervised machine learning	69
Hierarchical cumulative network for unsupervised medical image registration	69
IVD fibrosis and disc collapse comprehensively aggravate vertebral body disuse osteoporosis and zygapophyseal joint osteoarthritis by posteriorly shifting the load transmission pattern	69
The role of mechano-electric feedbacks and hemodynamic coupling in scar-related ventricular tachycardia	69
A deep learning based model using RNN-LSTM for the Detection of Schizophrenia from EEG data	68
Multi-label classification of fundus images with graph convolutional network and LightGBM	68
Emotion recognition in EEG signals using deep learning methods: A review	68
Contrastive learning based method for X-ray and CT registration under surgical equipment occlusion	68
MCA-net: A multi-task channel attention network for Myocardial infarction detection and location using 12-lead ECGs	68
Predicting diameter and tensile strength of electrospun fibers for biomedicine: A comparison of Box-Behnken design, traditional machine learning and deep learning	67
An efficient image segmentation method for skin cancer imaging using improved golden jackal optimization algorithm	67
DrugormerDTI: Drug Graphormer for drug–target interaction prediction	67
Automated tool detection with deep learning for monitoring kinematics and eye-hand coordination in microsurgery	67
REDDA: Integrating multiple biological relations to heterogeneous graph neural network for drug-disease association prediction	67
The role and potential of computer-aided drug discovery strategies in the discovery of novel antimicrobials	67
Visual prior-based cross-modal alignment network for radiology report generation	66
A review of deep learning-based information fusion techniques for multimodal medical image classification	66
Molecular modelling and experimental validation identified a new therapeutic inhibitor of toxoplasmosis	66
Structure-based design of promising natural products to inhibit thymidylate kinase from Monkeypox virus and validation using free energy calculations	66
Thyroid region prior guided attention for ultrasound segmentation of thyroid nodules	66
Exploring molecular mechanisms of diazinon toxicity in HT22 hippocampal neurons through integrated miRNA and mRNA profiling	65
Mass diffusion in multi-layer systems: an electrical analogue modelling approach	65
Editorial Board	65
A comprehensive analysis of single-cell RNA transcriptome reveals unique SPP1+ chondrocytes in human osteoarthritis	65
Molecular hybridization assisted multi-technique approach for designing USP21 inhibitors to halt catalytic triad-mediated nucleophilic attack and suppress pancreatic ductal adenocarcinoma progression:	65
Identification of telomere-associated gene signatures to predict prognosis and drug sensitivity in glioma	64
A novel virtual robotic platform for controlling six degrees of freedom assistive devices with body-machine interfaces	64
Estimation of potassium levels in hemodialysis patients by T wave nonlinear dynamics and morphology markers	64
A novel mTOR-associated gene signature for predicting prognosis and evaluating tumor immune microenvironment in lung adenocarcinoma	64
Joint cardiac tissue conductivity and activation time estimation using confirmatory factor analysis	62
SNN6mA: Improved DNA N6-methyladenine site prediction using Siamese network-based feature embedding	62
Editorial Board	62
Characterization of cancer subtypes associated with clinical outcomes by multi-omics integrative clustering	62
Bone marrow sparing oriented multi-model image registration in cervical cancer radiotherapy	62
Predicted and Explained: Transforming drug discovery with AI for high-precision receptor-ligand interaction modeling and binding analysis	62
Direct parametric reconstruction in dynamic PET using deep image prior and a novel parameter magnification strategy	62
Genetic algorithm based image reconstruction applying the digital holography process with the Discrete Orthonormal Stockwell Transform technique for diagnosis of COVID-19	62
Prediction of drug-target interactions via neural tangent kernel extraction feature matrix factorization model	62
Individual thigh muscle and proximal femoral features predict displacement in femoral neck Fractures: An AI-driven CT analysis	62
Editorial Board	61
MOSDNET: A multi-omics classification framework using simplified multi-view deep discriminant representation learning and dynamic edge GCN with multi-task learning	61
Role of [18F]-PSMA-1007 PET radiomics for seminal vesicle invasion prediction in primary prostate cancer	61
Designing a bioadjuvant candidate vaccine targeting infectious bursal disease virus (IBDV) using viral VP2 fusion and chicken IL-2 antigenic epitope: A bioinformatics approach	61
Alcohol patch test with hue-saturation-value model analysis predicts ALDH2 genetic polymorphism	61
Two-stage data augmentation for improved ASR performance for dysarthric speech	61
Lung nodule diagnosis and cancer histology classification from computed tomography data by convolutional neural networks: A survey	61
An unsupervised image registration method employing chest computed tomography images and deep neural networks	61
CISCA and CytoDArk0: A cell instance segmentation and classification method for histo(patho)logical image Analyses and a new, open, Nissl-stained dataset for brain cytoarchitecture studies	60
Cross attention guided multi-scale feature fusion for false-positive reduction in pulmonary nodule detection	60
Enhanced breast mass segmentation in mammograms using a hybrid transformer UNet model	60
Application of Explainable Artificial Intelligence for personalized childhood weight management using IoT data	60
Smoke veil prior regularized surgical field desmoking without paired in-vivo data	60
Systematic comparison of genome information processing and boundary recognition tools used for genomic island detection	60
Identification of key candidate genes and biological pathways in neuropathic pain	60
Potential anti-liver cancer targets and mechanisms of kaempferitrin based on network pharmacology, molecular docking and experimental verification	59
Genomic instability-related twelve-microRNA signatures for predicting the prognosis of gastric cancer	59
A multimodal deep learning framework for enzyme turnover prediction with missing modality	59
Enhancing search strategies for systematic reviews on drug Harms: An evaluation of the utility of ChatGPT in error detection and keyword generation	59
Spatiotemporal modeling of host–pathogen interactions using level-set method	59
SLT-Net: A codec network for skin lesion segmentation	59
Lightweight triangular mesh deformable reconstruction for low quality 3D organ models: Thickness noise and uneven topology	59
Atten-Nonlocal Unet: Attention and Non-local Unet for medical image segmentation	59
Impact of physiological loads of arterial wall on nucleus deformation in endothelial cells: A computational study	58
A regularization method to improve adversarial robustness of neural networks for ECG signal classification	58
A mechanobiological model for tumor spheroid evolution with application to glioblastoma: A continuum multiphysics approach	58
Multi-scale, multi-dimensional binocular endoscopic image depth estimation network	58
Effective fall detection and post-fall breath rate tracking using a low-cost CW Doppler radar sensor	57
A multi-granularity convolutional neural network model with temporal information and attention mechanism for efficient diabetes medical cost prediction	57
Application of artificial intelligence in drug design: A review	57
ACP-MLC: A two-level prediction engine for identification of anticancer peptides and multi-label classification of their functional types	57
Medical application of deep-learning-based head pose estimation from RGB image sequence	57
Cancer-inspired genomics mapper model for the generation of synthetic DNA sequences with desired genomics signatures	57
Breast cancer detection and classification: A study on the specification and implementation of multilayer perceptron analog artificial neural networks	57
Automatic segmentation and classification of Papanicolaou-stained cells and dataset for oral cancer detection	57
Enhancing nuclei segmentation in breast histopathology images using U-Net with backbone architectures	57
CFD simulations of inhalation through a subject-specific human larynx – Impact of the unilateral vocal fold immobility	56
FIM: A fatigued-injured muscle model based on the sliding filament theory	56
PNMC: Four-dimensional conebeam CT reconstruction combining prior network and motion compensation	56
Characterizing patients at higher cardiovascular risk for prescribed stimulants: Learning from health records data with predictive analytics and data mining techniques	56
Interplay of mutations, alternate mechanisms, and treatment breaks in leukaemia: Understanding and implications studied with stochastic models	56
DNA protein binding recognition based on lifelong learning	56
Hierarchical Harris hawks optimization for epileptic seizure classification	55
Patient-specific investigation into plaque rupture risk due to catheter tracking during TAVR	55
An automated parametric ear model to improve frugal 3D scanning methods for the advanced manufacturing of high-quality prosthetic ears	55
Building digital twins for personalized cardiovascular medicine: Advances, challenges, and future directions	55
Guardian-BERT: Early detection of self-injury and suicidal signs with language technologies in electronic health reports	55
A bidirectional registration neural network for cardiac motion tracking using cine MRI images	55
A sleep staging model on wavelet-based adaptive spectrogram reconstruction and light weight CNN	55
Respiratory modulation of the heart rate: A potential biomarker of cardiorespiratory function in human	55
Impact of surgical ventricular restoration on intracardiac hemodynamics: An in silico study using CCT data	55