Computers in Biology and Medicine

Article	Citations
Diffuse tumors: Molecular determinants shared by different cancer types	417
Editorial Board	360
Beyond accuracy: The need for explainable AI in biomedical voice technology	357
Discrepancy-based diffusion models for lesion detection in brain MRI	312
Identifying indications for novel drugs using electronic health records	310
Carotid single- and dual-layer stents reduce the wall adhesion of platelets by influencing flow and cellular transport	303
Pathogenicity classification of missense mutations based on deep generative model	302
Contrastive learning based method for X-ray and CT registration under surgical equipment occlusion	297
Eye movement analysis for real-world settings using segmented linear regression	292
Advances in disease detection through retinal imaging: A systematic review	290
Class-Specific Distribution Alignment for semi-supervised medical image classification	273
Discrete element method-based simulation system for predicting natural stone evacuation pathways in patients with urolithiasis	257
Fine-grained food image classification and recipe extraction using a customized deep neural network and NLP	245
Classical Simulations on Quantum Computers: Interface-Driven Peptide Folding on Simulated Membrane Surfaces	242
Adaptive nonlinear filtering algorithms for removal of non-stationary noise in electronystagmographic signals	234
Non-same-scale feature attention network based on BPD for medical image segmentation	221
Enhanced depression detection from speech using Quantum Whale Optimization Algorithm for feature selection	218
Deep learning and machine learning approaches to classify stomach distant metastatic tumors using DNA methylation profiles	204
Visual prior-based cross-modal alignment network for radiology report generation	193
Prediction of lung cancer metastasis by gene expression	192
Dual-Stream Subspace Clustering Network for revealing gene targets in Alzheimer's disease	187
Triage and monitoring of COVID-19 patients in intensive care using unsupervised machine learning	186
Dynamical pattern of successive bits to predict the outcomes of the SSRI and rTMS depression therapies using EEG signals	184
Structure, sensing and control of pneumatic upper limb rehabilitation system: Review and prospect	172
Efficient sleep apnea detection using single-lead ECG: A CNN-Transformer-LSTM approach	171

Single-channel EEG based insomnia detection with domain adaptation	163
You get the best of both worlds? Integrating deep learning and traditional machine learning for breast cancer risk prediction	162
Simulated annealing aided genetic algorithm for gene selection from microarray data	162
Wearable-based human flow experience recognition enhanced by transfer learning methods using emotion data	161
Insights into potential mechanisms of asthma patients with COVID-19: A study based on the gene expression profiling of bronchoalveolar lavage fluid	159
Automatic eczema classification in clinical images based on hybrid deep neural network	159
ST-SRPerf: Continuous spatiotemporal representation for perfusion MRI super-resolution through neural ODE and implicit neural representation	153
Automated mitral inflow Doppler peak velocity measurement using deep learning	152
KS-TMIL: A K-Stage Transformer approach with multiple instance learning model for ovarian cancer subtype classification	152
M3-Net++: A multi-scale, multi-level, multi-stream network for nuclei segmentation in breast cancer histopathology using hierarchical context extraction and hybrid loss optimization	148
FCSU-Net: A novel full-scale Cross-dimension Self-attention U-Net with collaborative fusion of multi-scale feature for medical image segmentation	147
Automated identification of patient subgroups: A case-study on mortality of COVID-19 patients admitted to the ICU	146
Vectorial-based analysis of dual-tracer PET imaging: A proof of concept	144
A novel mobile phone and tablet application for automatized calculation of pain extent	143
Dynamic topography analysis of the cornea and its application to the diagnosis of keratoconus	142
A computational model of the effects of macronutrients absorption and physical exercise on hormonal regulation and metabolic homeostasis	138
Identification of JUN as determinant of osteoarthritis and its inhibition by the Chinese herbal formulae Zhuanggu Huoxue Tang	137
Functional identification and prediction of lncRNAs in esophageal cancer	135
Editorial Board	135
Electroanatomical mapping of the stomach with simultaneous biomagnetic measurements	133
Evaluation of the mechanical behaviour of the expandable wedge locked nail fixation in retrograde use: A finite element study	133
Artificial vascular image generation using blood vessel texture maps	130
Drug repositioning for rosacea disease: Biological TARGET identification, molecular docking, pharmacophore mapping, and molecular dynamics analysis	129
Causal relationship between slow waves of arterial, intracranial pressures and blood velocity in brain	128
Towards a better understanding of TF-DNA binding prediction from genomic features	128
Deep learning-based feature discovery for decoding phenotypic plasticity in pediatric high-grade gliomas single-cell transcriptomics	128
Quantifying the influence of combined lung and kidney support using a cardiovascular model and sensitivity analysis-informed parameter identification	127
A self-supervised COVID-19 CT recognition system with multiple regularizations	126
Automatic segmentation of intraluminal thrombosis of abdominal aortic aneurysms from CT angiography using a mixed-scale-driven multiview perception network (M2Net) model	126
Data-driven discovery of sparse dynamical model of cardiovascular system for model predictive control	126
Eudesma-4(15), 7-dien-1-β-ol, A promising natural drug candidate for Alzheimer's disease targeting the NMDA pathway: GC-MS identification, molecular docking, pharmacokinetic and molecular dynamic anal	126
A mask R-CNN based automatic assessment system for nail psoriasis severity	126
Two-stage error detection to improve electron microscopy image mosaicking	122
Uniqueness of inspiratory airflow patterns in a realistic rat nasal cavity	122
MulStack: An ensemble learning prediction model of multilabel mRNA subcellular localization	122
JoCoRank: Joint correlation learning with ranking similarity regularization for imbalanced fetal brain age regression	121
Prediction of colorectal cancer based on taxonomic levels of microorganisms and discovery of taxonomic biomarkers using the Grouping-Scoring-Modeling (G-S-M) approach	121
Editorial Board	119
Disclosing neonatal pain in real-time: AI-derived pain sign from continuous assessment of facial expressions	118
Corrigendum to “Unraveling the molecular landscape of non-small cell lung cancer: Integrating bioinformatics and statistical approaches to identify biomarkers and drug repurposing” [Comput. Biol. Med.	118
Integrating CNN and Bi-LSTM for protein succinylation sites prediction based on Natural Language Processing technique	117
AIScholar: An OpenFaaS-enhanced cloud platform for intelligent medical data analytics	117
Semi-empirical Anticoagulation Model (SAM): Dose prediction during warfarin therapy	117
Predictive modeling for early detection of biliary atresia in infants with cholestasis: Insights from a machine learning study	116
A general sample-weighted framework for epileptic seizure prediction	114
A method for predicting linear and conformational B-cell epitopes in an antigen from its primary sequence	112
Unraveling the complexities of pathological voice through saliency analysis	112
Counting on AR: EEG responses to incongruent information with real-world context	112
Prediction of protein N-terminal acetylation modification sites based on CNN-BiLSTM-attention model	110
Enhancing and advancements in deep learning for melanoma detection: A comprehensive review	109

EpiTEAmDNA: Sequence feature representation via transfer learning and ensemble learning for identifying multiple DNA epigenetic modification types across species	109
DeepSMR: Decoding high-complex motor imagery via subject-dependent multi-feature refinement in deep convolutional networks	108
An efficient image segmentation method for skin cancer imaging using improved golden jackal optimization algorithm	107
Identification of lncRNA associated with the SERPINE1 gene in colorectal cancer through TGF-β pathway	107
Identification of potential agonist-like molecules for α2-adrenergic receptor by multi-layer virtual screening to combat sinusitis	107
Exploring the spike glycoprotein-encoding gene of SARS-CoV-2 using multifractal analysis: Unveiling structural complexity and implications for viral transmission	103
HOTGpred: Enhancing human O-linked threonine glycosylation prediction using integrated pretrained protein language model-based features and multi-stage feature selection approach	102
Deep-learning-based real-time individualization for reduce-order haemodynamic model	100
Red blood cell passage through deformable interendothelial slits in the spleen: Insights into splenic filtration and hemodynamics	100
Analysis of domain shift in whole prostate gland, zonal and lesions segmentation and detection, using multicentric retrospective data	100
A partially shared joint clustering framework for detecting protein complexes from multiple state-specific signed interaction networks	99
Development of closed-loop modelling framework for adaptive respiratory pacemakers	99
Predicting lung cancer survival based on clinical data using machine learning: A review	99
Insights from explainable AI in oesophageal cancer team decisions	98
SSMT-PANBERT: A single-stage multitask model for phenotype extraction and assertion negation detection in unstructured clinical text	98
Identifying fetal status with fetal heart rate: Deep learning approach based on long convolution	97
Computer models evaluating hand tremors in Parkinson's disease patients	96
Anemia prediction using gene expression programming (GEP) and explainable artificial intelligence approaches	96
Pedicle drilling force control of a robotic surgical system via spine-soft tissue coupling model and parameters optimization	94
Modelling of thrombus formation, growth and embolisation in the left atrial appendage under atrial fibrillation	89
DRBpred: A sequence-based machine learning method to effectively predict DNA- and RNA-binding residues	89
Numerical analysis of coil designs to expedite fracture healing using dielectrophoresis with S method	88
Context-aggregator: An approach of loss- and class imbalance-aware aggregation in federated learning	88
Automated mitral valve segmentation in PLAX-view transthoracic echocardiography for anatomical assessment and risk stratification	88
Identification of anti-cancer organometallic compounds by inhibition of BCL-2/Bax interactions	88
KNU-DTI: KNowledge United Drug-Target Interaction prediction	87
CauDR: A causality-inspired domain generalization framework for fundus-based diabetic retinopathy grading	87
Artificial intelligence for identification of candidates for device-aided therapy in Parkinson's disease: DELIST-PD study	87
Gene-related Parkinson's disease diagnosis via feature-based multi-branch octave convolution network	87
LSDVvac: An immunoinformatics database for vaccine design against lumpy skin disease virus	87
GasHisSDB: A new gastric histopathology image dataset for computer aided diagnosis of gastric cancer	86
Multi-constraint point set registration with redundant point removal for the registration of coronary arteries	86
Synergistic eigenanalysis of covariance and Hessian matrices for enhanced binary classification on health datasets	86
The role of the extracellular matrix in the reduction of lateral force transmission in muscle bundles: A finite element analysis	86
Optimization of deep learning models for inference in low resource environments	85
The role of mechano-electric feedbacks and hemodynamic coupling in scar-related ventricular tachycardia	85
KC-UNIT: Multi-kernel conversion using unpaired image-to-image translation with perceptual guidance in chest computed tomography imaging	84
Predicting diameter and tensile strength of electrospun fibers for biomedicine: A comparison of Box-Behnken design, traditional machine learning and deep learning	84
Temporal relative transformer encoding cooperating with channel attention for EEG emotion analysis	84
Context encoder transfer learning approaches for retinal image analysis	83
Enhancing cell instance segmentation in scanning electron microscopy images via a deep contour closing operator	83
CARES: A Corpus for classification of Spanish Radiological reports	83
Extinction and stationary distribution of a stochastic COVID-19 epidemic model with time-delay	83
Identifying potent natural inhibitors of the hepatitis C virus NS3 protein using multiple computational and molecular approaches	83
S2FLNet: Hepatic steatosis detection network with body shape	82
Revised NMS-driven pipeline for heart valve regurgitation and Kawasaki disease coronary aneurysm localization	82
A deep learning model combining convolutional neural networks and a selective kernel mechanism for SSVEP-Based BCIs	82
A computational study of venom as drug library: Discovery of multifunctional astacin-like metalloproteases from Androctonus zagrosensis venom gland transcriptome	79
Quantitative computed tomography imaging-based classification of cement dust-exposed subjects with an artificial neural network technique	79
Integrating biocomputational techniques for Breast cancer drug discovery via the HER-2, BCRA, VEGF and ER protein targets	79
AI-based bi-modal fusion system for automated clinical pain monitoring	79
D-glucose-conjugated thioureas containing 2-aminopyrimidine as potential multitarget inhibitors for type 2 diabetes mellitus: Synthesis and biological activity study	79
A novel hybrid ViT-LSTM model with explainable AI for brain stroke detection and classification in CT images: A case study of Rajshahi region	78
Multi-label classification of fundus images with graph convolutional network and LightGBM	78
Molecular modelling and experimental validation identified a new therapeutic inhibitor of toxoplasmosis	78
Structure-based design of promising natural products to inhibit thymidylate kinase from Monkeypox virus and validation using free energy calculations	78
An efficient model for extracting respiratory and blood oxygen saturation data from photoplethysmogram signals by removing motion artifacts using heuristic-aided ensemble learning model	78
ILSHIP: An interpretable and predictive model for hypothyroidism	78
Longitudinal dementia trajectories for Alzheimer’s Disease characterization and prediction	78
Hemodynamic alternations following stent deployment and post-dilation in a heavily calcified coronary artery: In silico and ex-vivo approaches	77
Automated tool detection with deep learning for monitoring kinematics and eye-hand coordination in microsurgery	77
A novel Harris Hawks Optimization-based clustering method for elucidating genetic associations in osteoarthritis and Diverse Cancer Types	77
Artificial intelligence techniques for prediction of drug synergy in malignant diseases: Past, present, and future	77
Enhancing targeted tumor treatment: A novel fuzzy logic framework for precision drug delivery strategy selection	77
Computational prediction of protein folding rate using structural parameters and network centrality measures	77
SURVS: A Swin-Unet and game theory-based unsupervised segmentation method for retinal vessel	77
AGNet: Automatic generation network for skin imaging reports	77
Reversing skin cancer adversarial examples by multiscale diffusive and denoising aggregation mechanism	76
Stack-AAgP: Computational prediction and interpretation of anti-angiogenic peptides using a meta-learning framework	76
Performance of multilabel machine learning models and risk stratification schemas for predicting stroke and bleeding risk in patients with non-valvular atrial fibrillation	75
Hybrid offline and self-knowledge distillation for acute ischemic stroke lesion segmentation from non-contrast CT scans	75
A Three-branch Jointed Feature and Topology Decoder guided by game-theoretic interactions for temporomandibular joint segmentation	74
Detecting IDH and TERTp mutations in diffuse gliomas using 1H-MRS with attention deep-shallow networks	74
DrugormerDTI: Drug Graphormer for drug–target interaction prediction	74
A robust drug recall supply chain management system using hyperledger blockchain ecosystem	74
Multiscale differential geometry learning of networks with applications to single-cell RNA sequencing data	73
IVD fibrosis and disc collapse comprehensively aggravate vertebral body disuse osteoporosis and zygapophyseal joint osteoarthritis by posteriorly shifting the load transmission pattern	73
An improved RIME optimization algorithm for lung cancer image segmentation	73
DE-JANet: A unified network based on dual encoder and joint attention for Alzheimer’s disease classification using multi-modal data	72
Dynamic Statistical Attention-based lightweight model for Retinal Vessel Segmentation: DyStA-RetNet	72

Explainable AI-driven prediction of influenza neuraminidase inhibitors using a stacked ensemble-learning framework	72
Mass diffusion in multi-layer systems: an electrical analogue modelling approach	71
A systematic review on the state-of-the-art strategies for protein representation	71
In silico evaluation of lattice designs for additively manufactured total hip implants	71
A deep learning based model using RNN-LSTM for the Detection of Schizophrenia from EEG data	70
Mapping synthetic binding proteins epitopes on diverse protein targets by protein structure prediction and protein-protein docking	70
Effect of tumor heterogeneity on enhancing drug delivery to vascularized tumors using thermo-sensitive liposomes triggered by hyperthermia: A multi-scale and multi-physics computational model	70
Improved predictive diagnosis of diabetic macular edema based on hybrid models: An observational study	69
Pharmacophore-guided computational modeling of quinolone-ATPase conjugate inhibitors targeting DNA GyrB subunit of Staphylococcus aureus	69
A transformer-based deep neural network for arrhythmia detection using continuous ECG signals	69
Hierarchical cumulative network for unsupervised medical image registration	68
MCA-net: A multi-task channel attention network for Myocardial infarction detection and location using 12-lead ECGs	68
A comprehensive analysis of single-cell RNA transcriptome reveals unique SPP1+ chondrocytes in human osteoarthritis	67
Thyroid region prior guided attention for ultrasound segmentation of thyroid nodules	67
The role and potential of computer-aided drug discovery strategies in the discovery of novel antimicrobials	67
COVID-19 diagnosis using state-of-the-art CNN architecture features and Bayesian Optimization	67
Graph neural network-based subgraph analysis for predicting adverse drug events	67
Deriving a suitable schedule through robust H	67
AELGNet: Attention-based Enhanced Local and Global Features Network for medicinal leaf and plant classification	67
Prostate158 - An expert-annotated 3T MRI dataset and algorithm for prostate cancer detection	67
A review of deep learning-based information fusion techniques for multimodal medical image classification	67
Emotion recognition in EEG signals using deep learning methods: A review	66
Development and validation of a neutrophil extracellular traps-related gene signature for lower-grade gliomas	66
Assessing clinical utility of machine learning and artificial intelligence approaches to analyze speech recordings in multiple sclerosis: A pilot study	66
REDDA: Integrating multiple biological relations to heterogeneous graph neural network for drug-disease association prediction	66
Sparse Dynamic Volume TransUNet with multi-level edge fusion for brain tumor segmentation	66
How CLSPN could demystify its prognostic value and potential molecular mechanism for hepatocellular carcinoma: A crosstalk study	66
Exploring molecular mechanisms of diazinon toxicity in HT22 hippocampal neurons through integrated miRNA and mRNA profiling	65
Molecular hybridization assisted multi-technique approach for designing USP21 inhibitors to halt catalytic triad-mediated nucleophilic attack and suppress pancreatic ductal adenocarcinoma progression:	65
A novel virtual robotic platform for controlling six degrees of freedom assistive devices with body-machine interfaces	65
Editorial Board	65
Identification of telomere-associated gene signatures to predict prognosis and drug sensitivity in glioma	64
Estimation of potassium levels in hemodialysis patients by T wave nonlinear dynamics and morphology markers	64
A novel mTOR-associated gene signature for predicting prognosis and evaluating tumor immune microenvironment in lung adenocarcinoma	64
Characterization of cancer subtypes associated with clinical outcomes by multi-omics integrative clustering	63
Genetic algorithm based image reconstruction applying the digital holography process with the Discrete Orthonormal Stockwell Transform technique for diagnosis of COVID-19	63
Joint cardiac tissue conductivity and activation time estimation using confirmatory factor analysis	63
Bone marrow sparing oriented multi-model image registration in cervical cancer radiotherapy	62
SNN6mA: Improved DNA N6-methyladenine site prediction using Siamese network-based feature embedding	62
Prediction of drug-target interactions via neural tangent kernel extraction feature matrix factorization model	62
Breast cancer detection and classification: A study on the specification and implementation of multilayer perceptron analog artificial neural networks	62
Editorial Board	61
Three-dimensional morphology scoring of hepatocellular carcinoma stratifies prognosis and immune infiltration	61
Direct parametric reconstruction in dynamic PET using deep image prior and a novel parameter magnification strategy	61
Individual thigh muscle and proximal femoral features predict displacement in femoral neck Fractures: An AI-driven CT analysis	61
Editorial Board	61
Predicted and Explained: Transforming drug discovery with AI for high-precision receptor-ligand interaction modeling and binding analysis	61
CFD simulations of inhalation through a subject-specific human larynx – Impact of the unilateral vocal fold immobility	61
A sleep staging model on wavelet-based adaptive spectrogram reconstruction and light weight CNN	60
Building digital twins for personalized cardiovascular medicine: Advances, challenges, and future directions	60
Interplay of mutations, alternate mechanisms, and treatment breaks in leukaemia: Understanding and implications studied with stochastic models	60
DNA protein binding recognition based on lifelong learning	60
Guardian-BERT: Early detection of self-injury and suicidal signs with language technologies in electronic health reports	60
Hierarchical Harris hawks optimization for epileptic seizure classification	60
FIM: A fatigued-injured muscle model based on the sliding filament theory	60
PEA-Net: A progressive edge information aggregation network for vessel segmentation	60
PNMC: Four-dimensional conebeam CT reconstruction combining prior network and motion compensation	60
Characterizing patients at higher cardiovascular risk for prescribed stimulants: Learning from health records data with predictive analytics and data mining techniques	60
Respiratory modulation of the heart rate: A potential biomarker of cardiorespiratory function in human	59
Patient-specific investigation into plaque rupture risk due to catheter tracking during TAVR	59
Radiology report generation using automatic keyword adaptation, frequency-based multi-label classification and text-to-text large language models	59
QMaxViT-Unet+: A query-based MaxViT-Unet with edge enhancement for scribble-supervised segmentation of medical images	59
Multi-scale, multi-dimensional binocular endoscopic image depth estimation network	59
An automated parametric ear model to improve frugal 3D scanning methods for the advanced manufacturing of high-quality prosthetic ears	59
Disruption of histidine biosynthesis in Acinetobacter baumannii by Tubuloside B from Cistanche tubulosa	59
ACP-MLC: A two-level prediction engine for identification of anticancer peptides and multi-label classification of their functional types	59
Immunoinformatics-driven In silico vaccine design for Nipah virus (NPV): Integrating machine learning and computational epitope prediction	59
Impact of surgical ventricular restoration on intracardiac hemodynamics: An in silico study using CCT data	59
DYNAFormer: Enhancing transformer segmentation with dynamic anchor mask for medical imaging	58
A bidirectional registration neural network for cardiac motion tracking using cine MRI images	58
A response-threshold method for early cancer diagnosis and monitoring via swarms of nanorobots	58
A computational framework to simulate the thermochemical process during thermochemical ablation of biological tissues	58
Metagenome comparison (MC): A new framework for detecting unique/enriched OMUs (operational metagenomic units) derived from whole-genome sequencing reads	57
Torque modulation mechanism of the knee joint during balance recovery	57
MG-Net: Multi-level global-aware network for thymoma segmentation	57
A mathematical model of tissue axial and radial diffusion in the microvasculature for intravascular microscopy and phosphorescence quenching data	57
GeneDX-PBMC: An adversarial autoencoder framework for unlocking Alzheimer's disease biomarkers using blood single-cell RNA sequencing data	57
SparseMorph: A weakly-supervised lightweight sparse transformer for mono- and multi-modal deformable image registration	57
Evaluation of Cellpose segmentation with sequential thresholding for instance segmentation of cytoplasms within autofluorescence images	57
Analysis and design of antithetic proportional-integral-derivative biocontrol-systems with species dilution	57
Novel classification of brain vascular tortuosity measures: A systematic review	57
A simplified method for relapsing-remitting multiple sclerosis detection: Insights from resting EEG signals	57
Alcohol patch test with hue-saturation-value model analysis predicts ALDH2 genetic polymorphism	56
Mechanical modeling of the maturation process for tissue-engineered implants: Application to biohybrid heart valves	56
Semi-supervised peripapillary atrophy segmentation with shape constraint	56
Identification of drug targets in pan-drug resistant Acinetobacter baumannii via whole genome sequencing and subtractive genomics	56
A fully-convolutional residual encoder-decoder neural network to localize breast cancer on histopathology images	56
Automatic segmentation and classification of Papanicolaou-stained cells and dataset for oral cancer detection	56
Impact of physiological loads of arterial wall on nucleus deformation in endothelial cells: A computational study	55
Collaborative networks of transformers and convolutional neural networks are powerful and versatile learners for accurate 3D medical image segmentation	55
SPMLD: A skin pathological image dataset for non-melanoma with detailed lesion area annotation	55
CACTUS: Multiview classifier for Punctate White Matter Lesions detection & segmentation in cranial ultrasound volumes	55
Tsallis statistics enhanced logistic regression for gene expression classification	55
Intelligent tuberculosis activity assessment system based on an ensemble of neural networks	55
A computational optimization study of a self-expandable transcatheter aortic valve	55