Computers in Biology and Medicine

Article	Citations
Editorial Board	463
Beyond accuracy: The need for explainable AI in biomedical voice technology	457
Eye movement analysis for real-world settings using segmented linear regression	405
Vectorial-based analysis of dual-tracer PET imaging: A proof of concept	394
A novel mobile phone and tablet application for automatized calculation of pain extent	373
Editorial Board	363
Electroanatomical mapping of the stomach with simultaneous biomagnetic measurements	361
Evaluation of the mechanical behaviour of the expandable wedge locked nail fixation in retrograde use: A finite element study	353
A self-supervised COVID-19 CT recognition system with multiple regularizations	347
Eudesma-4(15), 7-dien-1-β-ol, A promising natural drug candidate for Alzheimer's disease targeting the NMDA pathway: GC-MS identification, molecular docking, pharmacokinetic and molecular dynamic anal	339
FCSU-Net: A novel full-scale Cross-dimension Self-attention U-Net with collaborative fusion of multi-scale feature for medical image segmentation	336
Adaptive nonlinear filtering algorithms for removal of non-stationary noise in electronystagmographic signals	292
Mass diffusion in multi-layer systems: an electrical analogue modelling approach	282
An efficient model for extracting respiratory and blood oxygen saturation data from photoplethysmogram signals by removing motion artifacts using heuristic-aided ensemble learning model	278
LSDVvac: An immunoinformatics database for vaccine design against lumpy skin disease virus	276
Automated mitral valve segmentation in PLAX-view transthoracic echocardiography for anatomical assessment and risk stratification	274
DRBpred: A sequence-based machine learning method to effectively predict DNA- and RNA-binding residues	269
Discrete element method-based simulation system for predicting natural stone evacuation pathways in patients with urolithiasis	246
Deep learning and machine learning approaches to classify stomach distant metastatic tumors using DNA methylation profiles	237
DrugormerDTI: Drug Graphormer for drug–target interaction prediction	219
Semi-empirical Anticoagulation Model (SAM): Dose prediction during warfarin therapy	217
Pathogenicity classification of missense mutations based on deep generative model	217
Predicting lung cancer survival based on clinical data using machine learning: A review	214
A novel Harris Hawks Optimization-based clustering method for elucidating genetic associations in osteoarthritis and Diverse Cancer Types	209
Parameter sensitivity and critical transition anticipation in bistable toxin-antitoxin dynamics	207

Prediction of protein N-terminal acetylation modification sites based on CNN-BiLSTM-attention model	201
An efficient image segmentation method for skin cancer imaging using improved golden jackal optimization algorithm	198
Simulated annealing aided genetic algorithm for gene selection from microarray data	193
Context-aggregator: An approach of loss- and class imbalance-aware aggregation in federated learning	185
Artificial intelligence techniques for prediction of drug synergy in malignant diseases: Past, present, and future	184
Detecting IDH and TERTp mutations in diffuse gliomas using 1H-MRS with attention deep-shallow networks	178
AIScholar: An OpenFaaS-enhanced cloud platform for intelligent medical data analytics	177
Explainable AI-driven prediction of influenza neuraminidase inhibitors using a stacked ensemble-learning framework	176
Classical Simulations on Quantum Computers: Interface-Driven Peptide Folding on Simulated Membrane Surfaces	175
Dynamic Statistical Attention-based lightweight model for Retinal Vessel Segmentation: DyStA-RetNet	175
Discrepancy-based diffusion models for lesion detection in brain MRI	170
Multi-label classification of fundus images with graph convolutional network and LightGBM	169
Prediction of lung cancer metastasis by gene expression	162
An improved RIME optimization algorithm for lung cancer image segmentation	160
Hybrid offline and self-knowledge distillation for acute ischemic stroke lesion segmentation from non-contrast CT scans	157
Optimization of deep learning models for inference in low resource environments	156
Modelling of thrombus formation, growth and embolisation in the left atrial appendage under atrial fibrillation	155
AI-based bi-modal fusion system for automated clinical pain monitoring	155
Pharmacophore-guided computational modeling of quinolone-ATPase conjugate inhibitors targeting DNA GyrB subunit of Staphylococcus aureus	148
Molecular modelling and experimental validation identified a new therapeutic inhibitor of toxoplasmosis	147
Enhancing targeted tumor treatment: A novel fuzzy logic framework for precision drug delivery strategy selection	147
Insights from explainable AI in oesophageal cancer team decisions	142
Enhancing cell instance segmentation in scanning electron microscopy images via a deep contour closing operator	141
Automated mitral inflow Doppler peak velocity measurement using deep learning	139
Corrigendum to “Unraveling the molecular landscape of non-small cell lung cancer: Integrating bioinformatics and statistical approaches to identify biomarkers and drug repurposing” [Comput. Biol. Med.	138
Editorial Board	138
Optimizing multimodal models for medical visual question answering: A comparative study of LoRA and AdaLoRA on VQA-RAD and SLAKE-VQA	138
Identification of potential agonist-like molecules for α2-adrenergic receptor by multi-layer virtual screening to combat sinusitis	138
Computational prediction of protein folding rate using structural parameters and network centrality measures	136
MulStack: An ensemble learning prediction model of multilabel mRNA subcellular localization	134
Bayesian parameter inference and uncertainty-informed sensitivity analysis in a 0D cardiovascular model for intraoperative hypotension	131
DeepSMR: Decoding high-complex motor imagery via subject-dependent multi-feature refinement in deep convolutional networks	130
Numerical analysis of coil designs to expedite fracture healing using dielectrophoresis with S method	130
Data-driven discovery of sparse dynamical model of cardiovascular system for model predictive control	127
Wearable-based human flow experience recognition enhanced by transfer learning methods using emotion data	127
Anemia prediction using gene expression programming (GEP) and explainable artificial intelligence approaches	124
Dual-Stream Subspace Clustering Network for revealing gene targets in Alzheimer's disease	124
A computational study of venom as drug library: Discovery of multifunctional astacin-like metalloproteases from Androctonus zagrosensis venom gland transcriptome	123
Longitudinal dementia trajectories for Alzheimer’s Disease characterization and prediction	117
Assessing clinical utility of machine learning and artificial intelligence approaches to analyze speech recordings in multiple sclerosis: A pilot study	116
A computational model of the effects of macronutrients absorption and physical exercise on hormonal regulation and metabolic homeostasis	115
Two-stage error detection to improve electron microscopy image mosaicking	113
KC-UNIT: Multi-kernel conversion using unpaired image-to-image translation with perceptual guidance in chest computed tomography imaging	109
Enhanced depression detection from speech using Quantum Whale Optimization Algorithm for feature selection	105
M3-Net++: A multi-scale, multi-level, multi-stream network for nuclei segmentation in breast cancer histopathology using hierarchical context extraction and hybrid loss optimization	105
Artificial vascular image generation using blood vessel texture maps	101
Artificial intelligence for identification of candidates for device-aided therapy in Parkinson's disease: DELIST-PD study	101
JoCoRank: Joint correlation learning with ranking similarity regularization for imbalanced fetal brain age regression	101
Class-Specific Distribution Alignment for semi-supervised medical image classification	100
SURVS: A Swin-Unet and game theory-based unsupervised segmentation method for retinal vessel	99

KS-TMIL: A K-Stage Transformer approach with multiple instance learning model for ovarian cancer subtype classification	99
A partially shared joint clustering framework for detecting protein complexes from multiple state-specific signed interaction networks	98
Integrating biocomputational techniques for Breast cancer drug discovery via the HER-2, BCRA, VEGF and ER protein targets	98
Deep-learning-based real-time individualization for reduce-order haemodynamic model	98
Automatic eczema classification in clinical images based on hybrid deep neural network	97
Counting on AR: EEG responses to incongruent information with real-world context	97
Structure-based design of promising natural products to inhibit thymidylate kinase from Monkeypox virus and validation using free energy calculations	97
Gene-related Parkinson's disease diagnosis via feature-based multi-branch octave convolution network	97
Improved predictive diagnosis of diabetic macular edema based on hybrid models: An observational study	97
Dynamic topography analysis of the cornea and its application to the diagnosis of keratoconus	96
Non-same-scale feature attention network based on BPD for medical image segmentation	96
Deep learning-based feature discovery for decoding phenotypic plasticity in pediatric high-grade gliomas single-cell transcriptomics	95
Contrastive learning based method for X-ray and CT registration under surgical equipment occlusion	95
Identification of lncRNA associated with the SERPINE1 gene in colorectal cancer through TGF-β pathway	95
IVD fibrosis and disc collapse comprehensively aggravate vertebral body disuse osteoporosis and zygapophyseal joint osteoarthritis by posteriorly shifting the load transmission pattern	94
Temporal relative transformer encoding cooperating with channel attention for EEG emotion analysis	93
Revised NMS-driven pipeline for heart valve regurgitation and Kawasaki disease coronary aneurysm localization	93
ILSHIP: An interpretable and predictive model for hypothyroidism	93
Reversing skin cancer adversarial examples by multiscale diffusive and denoising aggregation mechanism	93
Exploring the spike glycoprotein-encoding gene of SARS-CoV-2 using multifractal analysis: Unveiling structural complexity and implications for viral transmission	93
Insights into potential mechanisms of asthma patients with COVID-19: A study based on the gene expression profiling of bronchoalveolar lavage fluid	92
EpiTEAmDNA: Sequence feature representation via transfer learning and ensemble learning for identifying multiple DNA epigenetic modification types across species	92
Identifying potent natural inhibitors of the hepatitis C virus NS3 protein using multiple computational and molecular approaches	88
ST-SRPerf: Continuous spatiotemporal representation for perfusion MRI super-resolution through neural ODE and implicit neural representation	88
Synergistic eigenanalysis of covariance and Hessian matrices for enhanced binary classification on health datasets	88
Towards a better understanding of TF-DNA binding prediction from genomic features	87
Carotid single- and dual-layer stents reduce the wall adhesion of platelets by influencing flow and cellular transport	86
Integrating CNN and Bi-LSTM for protein succinylation sites prediction based on Natural Language Processing technique	86
A general sample-weighted framework for epileptic seizure prediction	86
AELGNet: Attention-based Enhanced Local and Global Features Network for medicinal leaf and plant classification	85
A systematic review on the state-of-the-art strategies for protein representation	84
Mapping synthetic binding proteins epitopes on diverse protein targets by protein structure prediction and protein-protein docking	84
Automatic segmentation of intraluminal thrombosis of abdominal aortic aneurysms from CT angiography using a mixed-scale-driven multiview perception network (M2Net) model	83
Diffuse tumors: Molecular determinants shared by different cancer types	83
Predicting diameter and tensile strength of electrospun fibers for biomedicine: A comparison of Box-Behnken design, traditional machine learning and deep learning	82
Development and validation of a neutrophil extracellular traps-related gene signature for lower-grade gliomas	82
Hybrid neural–mechanistic modeling of leptospirosis transmission with environmental drivers: Evidence from Thailand	82
The role of the extracellular matrix in the reduction of lateral force transmission in muscle bundles: A finite element analysis	82
Pedicle drilling force control of a robotic surgical system via spine-soft tissue coupling model and parameters optimization	81
Identification of JUN as determinant of osteoarthritis and its inhibition by the Chinese herbal formulae Zhuanggu Huoxue Tang	81
Identification of anti-cancer organometallic compounds by inhibition of BCL-2/Bax interactions	81
Unraveling the complexities of pathological voice through saliency analysis	81
The role and potential of computer-aided drug discovery strategies in the discovery of novel antimicrobials	81
SSMT-PANBERT: A single-stage multitask model for phenotype extraction and assertion negation detection in unstructured clinical text	80
Drug repositioning for rosacea disease: Biological TARGET identification, molecular docking, pharmacophore mapping, and molecular dynamics analysis	79
In silico evaluation of lattice designs for additively manufactured total hip implants	79
HOTGpred: Enhancing human O-linked threonine glycosylation prediction using integrated pretrained protein language model-based features and multi-stage feature selection approach	79
Red blood cell passage through deformable interendothelial slits in the spleen: Insights into splenic filtration and hemodynamics	79
A deep learning based model using RNN-LSTM for the Detection of Schizophrenia from EEG data	78
REDDA: Integrating multiple biological relations to heterogeneous graph neural network for drug-disease association prediction	78
Identifying indications for novel drugs using electronic health records	78
Automated identification of patient subgroups: A case-study on mortality of COVID-19 patients admitted to the ICU	78
Analysis of domain shift in whole prostate gland, zonal and lesions segmentation and detection, using multicentric retrospective data	78
Disclosing neonatal pain in real-time: AI-derived pain sign from continuous assessment of facial expressions	77
Visual prior-based cross-modal alignment network for radiology report generation	77
A comprehensive analysis of single-cell RNA transcriptome reveals unique SPP1+ chondrocytes in human osteoarthritis	77
Functional identification and prediction of lncRNAs in esophageal cancer	77
D-glucose-conjugated thioureas containing 2-aminopyrimidine as potential multitarget inhibitors for type 2 diabetes mellitus: Synthesis and biological activity study	76
DE-JANet: A unified network based on dual encoder and joint attention for Alzheimer’s disease classification using multi-modal data	76
Graph neural network-based subgraph analysis for predicting adverse drug events	76
Deriving a suitable schedule through robust H	76
Sparse Dynamic Volume TransUNet with multi-level edge fusion for brain tumor segmentation	76
Emotion recognition in EEG signals using deep learning methods: A review	75
Prediction of colorectal cancer based on taxonomic levels of microorganisms and discovery of taxonomic biomarkers using the Grouping-Scoring-Modeling (G-S-M) approach	74
Stack-AAgP: Computational prediction and interpretation of anti-angiogenic peptides using a meta-learning framework	74
You get the best of both worlds? Integrating deep learning and traditional machine learning for breast cancer risk prediction	74
Thyroid region prior guided attention for ultrasound segmentation of thyroid nodules	74
A Three-branch Jointed Feature and Topology Decoder guided by game-theoretic interactions for temporomandibular joint segmentation	73
Predictive modeling for early detection of biliary atresia in infants with cholestasis: Insights from a machine learning study	73
Structure, sensing and control of pneumatic upper limb rehabilitation system: Review and prospect	73
Quantifying the influence of combined lung and kidney support using a cardiovascular model and sensitivity analysis-informed parameter identification	73
Efficient sleep apnea detection using single-lead ECG: A CNN-Transformer-LSTM approach	73
Imaging and machine learning reveal pigment ring spatial characteristics in vitiligo progression	72
Dynamical pattern of successive bits to predict the outcomes of the SSRI and rTMS depression therapies using EEG signals	72
Fusion-m6A: A lightweight hybrid deep learning framework for RNA m6A site prediction	72
AI unleashed: A meta-analysis transforming radiological insights in diagnosing abdominal infections	72
A review of deep learning-based information fusion techniques for multimodal medical image classification	71
A deep learning model combining convolutional neural networks and a selective kernel mechanism for SSVEP-Based BCIs	71
CARES: A Corpus for classification of Spanish Radiological reports	71
Simulated effects of the peripheral musculoskeletal system on hand tremor	71

Fine-grained food image classification and recipe extraction using a customized deep neural network and NLP	70
Multiscale differential geometry learning of networks with applications to single-cell RNA sequencing data	70
KNU-DTI: KNowledge United Drug-Target Interaction prediction	70
Identifying fetal status with fetal heart rate: Deep learning approach based on long convolution	70
A method for predicting linear and conformational B-cell epitopes in an antigen from its primary sequence	69
Effect of tumor heterogeneity on enhancing drug delivery to vascularized tumors using thermo-sensitive liposomes triggered by hyperthermia: A multi-scale and multi-physics computational model	69
CauDR: A causality-inspired domain generalization framework for fundus-based diabetic retinopathy grading	69
Prostate158 - An expert-annotated 3T MRI dataset and algorithm for prostate cancer detection	69
MOIS-SAM2: Exemplar-based segment anything model 2 for multi-lesion interactive segmentation of neurofibromas in whole-body MRI	68
Performance of multilabel machine learning models and risk stratification schemas for predicting stroke and bleeding risk in patients with non-valvular atrial fibrillation	68
Context encoder transfer learning approaches for retinal image analysis	68
A novel hybrid ViT-LSTM model with explainable AI for brain stroke detection and classification in CT images: A case study of Rajshahi region	67
Hierarchical cumulative network for unsupervised medical image registration	67
MCA-net: A multi-task channel attention network for Myocardial infarction detection and location using 12-lead ECGs	67
How CLSPN could demystify its prognostic value and potential molecular mechanism for hepatocellular carcinoma: A crosstalk study	67
A transformer-based deep neural network for arrhythmia detection using continuous ECG signals	67
Enhancing and advancements in deep learning for melanoma detection: A comprehensive review	66
Multi-constraint point set registration with redundant point removal for the registration of coronary arteries	66
Molecular hybridization assisted multi-technique approach for designing USP21 inhibitors to halt catalytic triad-mediated nucleophilic attack and suppress pancreatic ductal adenocarcinoma progression:	66
Advances in disease detection through retinal imaging: A systematic review	66
Joint cardiac tissue conductivity and activation time estimation using confirmatory factor analysis	65
Editorial Board	65
Prediction of drug-target interactions via neural tangent kernel extraction feature matrix factorization model	65
Editorial Board	65
Identification of telomere-associated gene signatures to predict prognosis and drug sensitivity in glioma	65
Genetic algorithm based image reconstruction applying the digital holography process with the Discrete Orthonormal Stockwell Transform technique for diagnosis of COVID-19	65
Individual thigh muscle and proximal femoral features predict displacement in femoral neck Fractures: An AI-driven CT analysis	65
Bone marrow sparing oriented multi-model image registration in cervical cancer radiotherapy	64
MicroRNA regulation of PPARG Signalling: Therapeutic implications for pulmonary hypertension	64
Transcriptome analysis displays new molecular insights into the mechanisms of action of Mebendazole in gastric cancer cells	64
MG-Net: Multi-level global-aware network for thymoma segmentation	64
Designing a bioadjuvant candidate vaccine targeting infectious bursal disease virus (IBDV) using viral VP2 fusion and chicken IL-2 antigenic epitope: A bioinformatics approach	64
Precision oncology informatics for anticancer drug combination responses: A systematic review	64
Smoke veil prior regularized surgical field desmoking without paired in-vivo data	64
Editorial Board	64
CISCA and CytoDArk0: A cell instance segmentation and classification method for histo(patho)logical image Analyses and a new, open, Nissl-stained dataset for brain cytoarchitecture studies	64
A sleep staging model on wavelet-based adaptive spectrogram reconstruction and light weight CNN	63
Role of [18F]-PSMA-1007 PET radiomics for seminal vesicle invasion prediction in primary prostate cancer	63
Lightweight triangular mesh deformable reconstruction for low quality 3D organ models: Thickness noise and uneven topology	63
Spatiotemporal modeling of host–pathogen interactions using level-set method	62
FIM: A fatigued-injured muscle model based on the sliding filament theory	61
Characterizing patients at higher cardiovascular risk for prescribed stimulants: Learning from health records data with predictive analytics and data mining techniques	61
PNMC: Four-dimensional conebeam CT reconstruction combining prior network and motion compensation	61
Breast cancer detection and classification: A study on the specification and implementation of multilayer perceptron analog artificial neural networks	61
Pathological prognosis classification of patients with neuroblastoma using computational pathology analysis	60
Enhanced breast mass segmentation in mammograms using a hybrid transformer UNet model	60
An efficient cardiovascular disease prediction model through AI-driven IoT technology	60
SWTRU: Star-shaped Window Transformer Reinforced U-Net for medical image segmentation	60
NSICA: Multi-objective imperialist competitive algorithm for feature selection in arrhythmia diagnosis	60
Wearable multisource quantitative gait analysis of Parkinson's diseases	60
Fractional-order safe mental-health corridor modelling with Matignon spectral analysis of post-pandemic fatigue-to-recovery dynamics	60
N6-methyladenosine RNA methylation regulators and their target SOX2 as circulating biomarkers of colorectal cancer: Insights towards early diagnosis and staging	60
SEPO-FI: Deep-learning based software to calculate fusion index of muscle cells	60
Hierarchical Harris hawks optimization for epileptic seizure classification	59
Computer modeling of radiofrequency cardiac ablation including heartbeat-induced electrode displacement	59
Building digital twins for personalized cardiovascular medicine: Advances, challenges, and future directions	59
Characterization of cancer subtypes associated with clinical outcomes by multi-omics integrative clustering	59
Impact of surgical ventricular restoration on intracardiac hemodynamics: An in silico study using CCT data	59
A fully-convolutional residual encoder-decoder neural network to localize breast cancer on histopathology images	59
Patient-specific investigation into plaque rupture risk due to catheter tracking during TAVR	59
Integrating local and global attention mechanisms for enhanced oral cancer detection and explainability	58
A mathematical model of tissue axial and radial diffusion in the microvasculature for intravascular microscopy and phosphorescence quenching data	58
A multimodal deep learning framework for enzyme turnover prediction with missing modality	58
A computational framework to simulate the thermochemical process during thermochemical ablation of biological tissues	58
A wrapper method for finding optimal subset of multimodal Magnetic Resonance Imaging sequences for ischemic stroke lesion segmentation	58
GeneDX-PBMC: An adversarial autoencoder framework for unlocking Alzheimer's disease biomarkers using blood single-cell RNA sequencing data	58
An automated parametric ear model to improve frugal 3D scanning methods for the advanced manufacturing of high-quality prosthetic ears	58
Enhanced single-cell RNA-seq embedding through gene expression and data-driven gene-gene interaction integration	57
Classifying alkaliphilic proteins using embeddings from protein language model	57
A regularization method to improve adversarial robustness of neural networks for ECG signal classification	57
Identification of molecular and cellular infection response biomarkers associated with anthrax infection through comparative analysis of gene expression data	57
A multiwavelet-based sparse time-varying autoregressive modeling for motor imagery EEG classification	57
Mechanical modeling of the maturation process for tissue-engineered implants: Application to biohybrid heart valves	56
Torque modulation mechanism of the knee joint during balance recovery	56
Artificial intelligence derived categorizations significantly improve HOMA IR/β indicators: Combating diabetes through cross-interacting drugs	55
DYNAFormer: Enhancing transformer segmentation with dynamic anchor mask for medical imaging	55
Analysis and design of antithetic proportional-integral-derivative biocontrol-systems with species dilution	55
Ce	55
A response-threshold method for early cancer diagnosis and monitoring via swarms of nanorobots	55
Impact of workflow variability on image-based intracranial aneurysm hemodynamics	54
A simplified method for relapsing-remitting multiple sclerosis detection: Insights from resting EEG signals	54
Intelligent tuberculosis activity assessment system based on an ensemble of neural networks	54
Repeated measures analysis for steady-state evoked potentials	54
Enclosing 95% confidence area and volume to center of pressure and center of mass in posturography using optimization algorithm and coordinate ascent methods	54
SNN6mA: Improved DNA N6-methyladenine site prediction using Siamese network-based feature embedding	53
Enhancing search strategies for systematic reviews on drug Harms: An evaluation of the utility of ChatGPT in error detection and keyword generation	53
Identification of a novel gene signature for the prognosis of sepsis	53
Deep networks for behavioral variant frontotemporal dementia identification from multiple acquisition sources	53
Cross attention guided multi-scale feature fusion for false-positive reduction in pulmonary nodule detection	53
Metagenome comparison (MC): A new framework for detecting unique/enriched OMUs (operational metagenomic units) derived from whole-genome sequencing reads	53
Validation of fluid-structure interaction simulations of the opening phase of phantom mitral heart valves under physiologically inspired conditions	53
A lightweight convolutional neural network hardware implementation for wearable heart rate anomaly detection	52
Predicted and Explained: Transforming drug discovery with AI for high-precision receptor-ligand interaction modeling and binding analysis	52
PEA-Net: A progressive edge information aggregation network for vessel segmentation	52
Collaborative networks of transformers and convolutional neural networks are powerful and versatile learners for accurate 3D medical image segmentation	52