Computers in Biology and Medicine

Article	Citations
Editorial Board	475
Eye movement analysis for real-world settings using segmented linear regression	472
Vectorial-based analysis of dual-tracer PET imaging: A proof of concept	424
A novel mobile phone and tablet application for automatized calculation of pain extent	407
Electroanatomical mapping of the stomach with simultaneous biomagnetic measurements	386
Evaluation of the mechanical behaviour of the expandable wedge locked nail fixation in retrograde use: A finite element study	378
A self-supervised COVID-19 CT recognition system with multiple regularizations	353
Eudesma-4(15), 7-dien-1-β-ol, A promising natural drug candidate for Alzheimer's disease targeting the NMDA pathway: GC-MS identification, molecular docking, pharmacokinetic and molecular dynamic anal	344
FCSU-Net: A novel full-scale Cross-dimension Self-attention U-Net with collaborative fusion of multi-scale feature for medical image segmentation	303
Adaptive nonlinear filtering algorithms for removal of non-stationary noise in electronystagmographic signals	287
Mass diffusion in multi-layer systems: an electrical analogue modelling approach	286
Discrete element method-based simulation system for predicting natural stone evacuation pathways in patients with urolithiasis	285
Deep learning and machine learning approaches to classify stomach distant metastatic tumors using DNA methylation profiles	284
DrugormerDTI: Drug Graphormer for drug–target interaction prediction	276
Pathogenicity classification of missense mutations based on deep generative model	257
A novel Harris Hawks Optimization-based clustering method for elucidating genetic associations in osteoarthritis and Diverse Cancer Types	242
Parameter sensitivity and critical transition anticipation in bistable toxin-antitoxin dynamics	221
Prediction of protein N-terminal acetylation modification sites based on CNN-BiLSTM-attention model	221
Simulated annealing aided genetic algorithm for gene selection from microarray data	220
Context-aggregator: An approach of loss- and class imbalance-aware aggregation in federated learning	218
AIScholar: An OpenFaaS-enhanced cloud platform for intelligent medical data analytics	216
Explainable AI-driven prediction of influenza neuraminidase inhibitors using a stacked ensemble-learning framework	209
Discrepancy-based diffusion models for lesion detection in brain MRI	204
Prediction of lung cancer metastasis by gene expression	199
An improved RIME optimization algorithm for lung cancer image segmentation	190

AI-based bi-modal fusion system for automated clinical pain monitoring	188
Pharmacophore-guided computational modeling of quinolone-ATPase conjugate inhibitors targeting DNA GyrB subunit of Staphylococcus aureus	183
Enhancing targeted tumor treatment: A novel fuzzy logic framework for precision drug delivery strategy selection	182
Molecular modelling and experimental validation identified a new therapeutic inhibitor of toxoplasmosis	182
Optimizing multimodal models for medical visual question answering: A comparative study of LoRA and AdaLoRA on VQA-RAD and SLAKE-VQA	180
Corrigendum to “Unraveling the molecular landscape of non-small cell lung cancer: Integrating bioinformatics and statistical approaches to identify biomarkers and drug repurposing” [Comput. Biol. Med.	178
Identification of potential agonist-like molecules for α2-adrenergic receptor by multi-layer virtual screening to combat sinusitis	175
Editorial Board	175
Computational prediction of protein folding rate using structural parameters and network centrality measures	165
MulStack: An ensemble learning prediction model of multilabel mRNA subcellular localization	165
Wearable-based human flow experience recognition enhanced by transfer learning methods using emotion data	162
Data-driven discovery of sparse dynamical model of cardiovascular system for model predictive control	160
Dual-Stream Subspace Clustering Network for revealing gene targets in Alzheimer's disease	159
A computational study of venom as drug library: Discovery of multifunctional astacin-like metalloproteases from Androctonus zagrosensis venom gland transcriptome	156
Assessing clinical utility of machine learning and artificial intelligence approaches to analyze speech recordings in multiple sclerosis: A pilot study	151
A computational model of the effects of macronutrients absorption and physical exercise on hormonal regulation and metabolic homeostasis	149
Two-stage error detection to improve electron microscopy image mosaicking	147
Enhanced depression detection from speech using Quantum Whale Optimization Algorithm for feature selection	145
Artificial vascular image generation using blood vessel texture maps	144
Artificial intelligence for identification of candidates for device-aided therapy in Parkinson's disease: DELIST-PD study	142
A partially shared joint clustering framework for detecting protein complexes from multiple state-specific signed interaction networks	142
Counting on AR: EEG responses to incongruent information with real-world context	141
Improved predictive diagnosis of diabetic macular edema based on hybrid models: An observational study	140
Gene-related Parkinson's disease diagnosis via feature-based multi-branch octave convolution network	138
Non-same-scale feature attention network based on BPD for medical image segmentation	136
Dynamic topography analysis of the cornea and its application to the diagnosis of keratoconus	134
Deep learning-based feature discovery for decoding phenotypic plasticity in pediatric high-grade gliomas single-cell transcriptomics	132
Revised NMS-driven pipeline for heart valve regurgitation and Kawasaki disease coronary aneurysm localization	130
IVD fibrosis and disc collapse comprehensively aggravate vertebral body disuse osteoporosis and zygapophyseal joint osteoarthritis by posteriorly shifting the load transmission pattern	130
Reversing skin cancer adversarial examples by multiscale diffusive and denoising aggregation mechanism	129
ILSHIP: An interpretable and predictive model for hypothyroidism	127
EpiTEAmDNA: Sequence feature representation via transfer learning and ensemble learning for identifying multiple DNA epigenetic modification types across species	125
Insights into potential mechanisms of asthma patients with COVID-19: A study based on the gene expression profiling of bronchoalveolar lavage fluid	124
A novel hybrid ViT-LSTM model with explainable AI for brain stroke detection and classification in CT images: A case study of Rajshahi region	124
Graph neural network-based subgraph analysis for predicting adverse drug events	121
HOTGpred: Enhancing human O-linked threonine glycosylation prediction using integrated pretrained protein language model-based features and multi-stage feature selection approach	118
A deep learning based model using RNN-LSTM for the Detection of Schizophrenia from EEG data	116
Enhancing cell instance segmentation in scanning electron microscopy images via a deep contour closing operator	110
The role and potential of computer-aided drug discovery strategies in the discovery of novel antimicrobials	108
Longitudinal dementia trajectories for Alzheimer’s Disease characterization and prediction	105
Deriving a suitable schedule through robust H∞ and sliding mode control methods for cancer treatment using chemotherapy & anti-angiogenic drugs	103
Classical Simulations on Quantum Computers: Interface-Driven Peptide Folding on Simulated Membrane Surfaces	103
Structure-based design of promising natural products to inhibit thymidylate kinase from Monkeypox virus and validation using free energy calculations	102
Contrastive learning based method for X-ray and CT registration under surgical equipment occlusion	102
Hybrid offline and self-knowledge distillation for acute ischemic stroke lesion segmentation from non-contrast CT scans	102
Automatic segmentation of intraluminal thrombosis of abdominal aortic aneurysms from CT angiography using a mixed-scale-driven multiview perception network (M2Net) model	101
Dynamic Statistical Attention-based lightweight model for Retinal Vessel Segmentation: DyStA-RetNet	101
An efficient image segmentation method for skin cancer imaging using improved golden jackal optimization algorithm	100
Bayesian parameter inference and uncertainty-informed sensitivity analysis in a 0D cardiovascular model for intraoperative hypotension	100
CauDR: A causality-inspired domain generalization framework for fundus-based diabetic retinopathy grading	99

Efficient sleep apnea detection using single-lead ECG: A CNN-Transformer-LSTM approach	99
Imaging and machine learning reveal pigment ring spatial characteristics in vitiligo progression	98
AI unleashed: A meta-analysis transforming radiological insights in diagnosing abdominal infections	97
Integrating biocomputational techniques for Breast cancer drug discovery via the HER-2, BCRA, VEGF and ER protein targets	97
Fusion-m6A: A lightweight hybrid deep learning framework for RNA m6A site prediction	97
Simulated effects of the peripheral musculoskeletal system on hand tremor	97
Red blood cell passage through deformable interendothelial slits in the spleen: Insights into splenic filtration and hemodynamics	96
Numerical analysis of coil designs to expedite fracture healing using dielectrophoresis with S method	95
JoCoRank: Joint correlation learning with ranking similarity regularization for imbalanced fetal brain age regression	95
Beyond accuracy: The need for explainable AI in biomedical voice technology	95
Fine-grained food image classification and recipe extraction using a customized deep neural network and NLP	95
You get the best of both worlds? Integrating deep learning and traditional machine learning for breast cancer risk prediction	94
DRBpred: A sequence-based machine learning method to effectively predict DNA- and RNA-binding residues	93
Hybrid neural–mechanistic modeling of leptospirosis transmission with environmental drivers: Evidence from Thailand	93
Modelling of thrombus formation, growth and embolisation in the left atrial appendage under atrial fibrillation	93
Identification of lncRNA associated with the SERPINE1 gene in colorectal cancer through TGF-β pathway	88
Synergistic eigenanalysis of covariance and Hessian matrices for enhanced binary classification on health datasets	88
Semi-empirical Anticoagulation Model (SAM): Dose prediction during warfarin therapy	88
CARES: A Corpus for classification of Spanish Radiological reports	86
SSMT-PANBERT: A single-stage multitask model for phenotype extraction and assertion negation detection in unstructured clinical text	86
LSDVvac: An immunoinformatics database for vaccine design against lumpy skin disease virus	86
Multiscale differential geometry learning of networks with applications to single-cell RNA sequencing data	86
Enhancing and advancements in deep learning for melanoma detection: A comprehensive review	86
How CLSPN could demystify its prognostic value and potential molecular mechanism for hepatocellular carcinoma: A crosstalk study	85
Hierarchical cumulative network for unsupervised medical image registration	85
MCA-net: A multi-task channel attention network for Myocardial infarction detection and location using 12-lead ECGs	85
Multi-constraint point set registration with redundant point removal for the registration of coronary arteries	84
Predictive modeling for early detection of biliary atresia in infants with cholestasis: Insights from a machine learning study	83
A method for predicting linear and conformational B-cell epitopes in an antigen from its primary sequence	83
Context encoder transfer learning approaches for retinal image analysis	83
MOIS-SAM2: Exemplar-based segment anything model 2 for multi-lesion interactive segmentation of neurofibromas in whole-body MRI	83
Pedicle drilling force control of a robotic surgical system via spine-soft tissue coupling model and parameters optimization	81
Development and validation of a neutrophil extracellular traps-related gene signature for lower-grade gliomas	81
Identifying indications for novel drugs using electronic health records	81
The role of the extracellular matrix in the reduction of lateral force transmission in muscle bundles: A finite element analysis	81
Stack-AAgP: Computational prediction and interpretation of anti-angiogenic peptides using a meta-learning framework	81
Identification of JUN as determinant of osteoarthritis and its inhibition by the Chinese herbal formulae Zhuanggu Huoxue Tang	81
Diffuse tumors: Molecular determinants shared by different cancer types	81
Towards a better understanding of TF-DNA binding prediction from genomic features	80
Integrating CNN and Bi-LSTM for protein succinylation sites prediction based on Natural Language Processing technique	80
Carotid single- and dual-layer stents reduce the wall adhesion of platelets by influencing flow and cellular transport	80
A general sample-weighted framework for epileptic seizure prediction	80
Identification of anti-cancer organometallic compounds by inhibition of BCL-2/Bax interactions	80
AELGNet: Attention-based Enhanced Local and Global Features Network for medicinal leaf and plant classification	80
Dynamical pattern of successive bits to predict the outcomes of the SSRI and rTMS depression therapies using EEG signals	79
Quantifying the influence of combined lung and kidney support using a cardiovascular model and sensitivity analysis-informed parameter identification	79
Structure, sensing and control of pneumatic upper limb rehabilitation system: Review and prospect	79
A systematic review on the state-of-the-art strategies for protein representation	79
A deep learning model combining convolutional neural networks and a selective kernel mechanism for SSVEP-Based BCIs	79
A Three-branch Jointed Feature and Topology Decoder guided by game-theoretic interactions for temporomandibular joint segmentation	79
Functional identification and prediction of lncRNAs in esophageal cancer	78
Automated identification of patient subgroups: A case-study on mortality of COVID-19 patients admitted to the ICU	78
Analysis of domain shift in whole prostate gland, zonal and lesions segmentation and detection, using multicentric retrospective data	78
Disclosing neonatal pain in real-time: AI-derived pain sign from continuous assessment of facial expressions	78
Identifying fetal status with fetal heart rate: Deep learning approach based on long convolution	78
Visual prior-based cross-modal alignment network for radiology report generation	78
KNU-DTI: KNowledge United Drug-Target Interaction prediction	78
Unraveling the complexities of pathological voice through saliency analysis	77
M3-Net++: A multi-scale, multi-level, multi-stream network for nuclei segmentation in breast cancer histopathology using hierarchical context extraction and hybrid loss optimization	76
DeepSMR: Decoding high-complex motor imagery via subject-dependent multi-feature refinement in deep convolutional networks	76
Anemia prediction using gene expression programming (GEP) and explainable artificial intelligence approaches	74
Exploring the spike glycoprotein-encoding gene of SARS-CoV-2 using multifractal analysis: Unveiling structural complexity and implications for viral transmission	74
KC-UNIT: Multi-kernel conversion using unpaired image-to-image translation with perceptual guidance in chest computed tomography imaging	74
Automated mitral valve segmentation in PLAX-view transthoracic echocardiography for anatomical assessment and risk stratification	74
Optimization of deep learning models for inference in low resource environments	74
KS-TMIL: A K-Stage Transformer approach with multiple instance learning model for ovarian cancer subtype classification	74
Effect of tumor heterogeneity on enhancing drug delivery to vascularized tumors using thermo-sensitive liposomes triggered by hyperthermia: A multi-scale and multi-physics computational model	73
REDDA: Integrating multiple biological relations to heterogeneous graph neural network for drug-disease association prediction	73
Emotion recognition in EEG signals using deep learning methods: A review	73
Predicting diameter and tensile strength of electrospun fibers for biomedicine: A comparison of Box-Behnken design, traditional machine learning and deep learning	73
DE-JANet: A unified network based on dual encoder and joint attention for Alzheimer’s disease classification using multi-modal data	73
Identifying potent natural inhibitors of the hepatitis C virus NS3 protein using multiple computational and molecular approaches	73
A review of deep learning-based information fusion techniques for multimodal medical image classification	72
Drug repositioning for rosacea disease: Biological TARGET identification, molecular docking, pharmacophore mapping, and molecular dynamics analysis	72
A comprehensive analysis of single-cell RNA transcriptome reveals unique SPP1+ chondrocytes in human osteoarthritis	72
Automatic eczema classification in clinical images based on hybrid deep neural network	71
Detecting IDH and TERTp mutations in diffuse gliomas using 1H-MRS with attention deep-shallow networks	70
Advances in disease detection through retinal imaging: A systematic review	70
Predicting lung cancer survival based on clinical data using machine learning: A review	70
Temporal relative transformer encoding cooperating with channel attention for EEG emotion analysis	70

D-glucose-conjugated thioureas containing 2-aminopyrimidine as potential multitarget inhibitors for type 2 diabetes mellitus: Synthesis and biological activity study	70
Performance of multilabel machine learning models and risk stratification schemas for predicting stroke and bleeding risk in patients with non-valvular atrial fibrillation	69
Automated mitral inflow Doppler peak velocity measurement using deep learning	68
SURVS: A Swin-Unet and game theory-based unsupervised segmentation method for retinal vessel	68
Mapping synthetic binding proteins epitopes on diverse protein targets by protein structure prediction and protein-protein docking	68
Multi-label classification of fundus images with graph convolutional network and LightGBM	68
An efficient model for extracting respiratory and blood oxygen saturation data from photoplethysmogram signals by removing motion artifacts using heuristic-aided ensemble learning model	68
Prostate158 - An expert-annotated 3T MRI dataset and algorithm for prostate cancer detection	67
Insights from explainable AI in oesophageal cancer team decisions	67
Class-Specific Distribution Alignment for semi-supervised medical image classification	67
Sparse Dynamic Volume TransUNet with multi-level edge fusion for brain tumor segmentation	67
Identification of telomere-associated gene signatures to predict prognosis and drug sensitivity in glioma	66
Deep-learning-based real-time individualization for reduce-order haemodynamic model	66
ST-SRPerf: Continuous spatiotemporal representation for perfusion MRI super-resolution through neural ODE and implicit neural representation	66
Editorial Board	66
Prediction of colorectal cancer based on taxonomic levels of microorganisms and discovery of taxonomic biomarkers using the Grouping-Scoring-Modeling (G-S-M) approach	66
Molecular hybridization assisted multi-technique approach for designing USP21 inhibitors to halt catalytic triad-mediated nucleophilic attack and suppress pancreatic ductal adenocarcinoma progression:	66
Thyroid region prior guided attention for ultrasound segmentation of thyroid nodules	66
MG-Net: Multi-level global-aware network for thymoma segmentation	65
Genetic algorithm based image reconstruction applying the digital holography process with the Discrete Orthonormal Stockwell Transform technique for diagnosis of COVID-19	65
Designing a bioadjuvant candidate vaccine targeting infectious bursal disease virus (IBDV) using viral VP2 fusion and chicken IL-2 antigenic epitope: A bioinformatics approach	65
Prediction of drug-target interactions via neural tangent kernel extraction feature matrix factorization model	65
Smoke veil prior regularized surgical field desmoking without paired in-vivo data	65
FIM: A fatigued-injured muscle model based on the sliding filament theory	64
Lightweight triangular mesh deformable reconstruction for low quality 3D organ models: Thickness noise and uneven topology	64
Characterizing patients at higher cardiovascular risk for prescribed stimulants: Learning from health records data with predictive analytics and data mining techniques	64
Role of [18F]-PSMA-1007 PET radiomics for seminal vesicle invasion prediction in primary prostate cancer	64
Transcriptome analysis displays new molecular insights into the mechanisms of action of Mebendazole in gastric cancer cells	64
Spatiotemporal modeling of host–pathogen interactions using level-set method	64
A sleep staging model on wavelet-based adaptive spectrogram reconstruction and light weight CNN	64
SWTRU: Star-shaped Window Transformer Reinforced U-Net for medical image segmentation	63
Pathological prognosis classification of patients with neuroblastoma using computational pathology analysis	63
N6-methyladenosine RNA methylation regulators and their target SOX2 as circulating biomarkers of colorectal cancer: Insights towards early diagnosis and staging	63
NSICA: Multi-objective imperialist competitive algorithm for feature selection in arrhythmia diagnosis	62
A multiwavelet-based sparse time-varying autoregressive modeling for motor imagery EEG classification	61
An automated parametric ear model to improve frugal 3D scanning methods for the advanced manufacturing of high-quality prosthetic ears	61
Hierarchical Harris hawks optimization for epileptic seizure classification	61
SEPO-FI: Deep-learning based software to calculate fusion index of muscle cells	61
A computational framework to simulate the thermochemical process during thermochemical ablation of biological tissues	61
Enhanced single-cell RNA-seq embedding through gene expression and data-driven gene-gene interaction integration	61
Building digital twins for personalized cardiovascular medicine: Advances, challenges, and future directions	61
A wrapper method for finding optimal subset of multimodal Magnetic Resonance Imaging sequences for ischemic stroke lesion segmentation	61
A fully-convolutional residual encoder-decoder neural network to localize breast cancer on histopathology images	61
Classifying alkaliphilic proteins using embeddings from protein language model	60
Mechanical modeling of the maturation process for tissue-engineered implants: Application to biohybrid heart valves	60
A response-threshold method for early cancer diagnosis and monitoring via swarms of nanorobots	60
Torque modulation mechanism of the knee joint during balance recovery	60
DYNAFormer: Enhancing transformer segmentation with dynamic anchor mask for medical imaging	60
Identification of molecular and cellular infection response biomarkers associated with anthrax infection through comparative analysis of gene expression data	60
Two-stage data augmentation for improved ASR performance for dysarthric speech	59
Characterization of cancer subtypes associated with clinical outcomes by multi-omics integrative clustering	59
Energy consumption during insect flight and bioinspiration for MAV design: A review	59
Effective fall detection and post-fall breath rate tracking using a low-cost CW Doppler radar sensor	59
Modelling antibiotic delivery from functionally graded materials to target biofilm-associated infections	59
QMaxViT-Unet+: A query-based MaxViT-Unet with edge enhancement for scribble-supervised segmentation of medical images	59
Alcohol patch test with hue-saturation-value model analysis predicts ALDH2 genetic polymorphism	59
A novel mTOR-associated gene signature for predicting prognosis and evaluating tumor immune microenvironment in lung adenocarcinoma	59
Fractional-order safe mental-health corridor modelling with Matignon spectral analysis of post-pandemic fatigue-to-recovery dynamics	58
Enhanced breast mass segmentation in mammograms using a hybrid transformer UNet model	58
Atten-Nonlocal Unet: Attention and Non-local Unet for medical image segmentation	58
Repeated measures analysis for steady-state evoked potentials	58
Optimized Complex-Valued Spatio-Temporal Graph Convolutional Networks for attention deficit hyperactivity disorder detection in pediatric EEG signals	57
A simplified method for relapsing-remitting multiple sclerosis detection: Insights from resting EEG signals	57
An unsupervised image registration method employing chest computed tomography images and deep neural networks	57
Radiology report generation using automatic keyword adaptation, frequency-based multi-label classification and text-to-text large language models	56
Breast cancer detection and classification: A study on the specification and implementation of multilayer perceptron analog artificial neural networks	56
An adaptive language model-based intelligent medication assistant for the decision support of antidepressant prescriptions	56
Exploring molecular mechanisms of diazinon toxicity in HT22 hippocampal neurons through integrated miRNA and mRNA profiling	55
PNMC: Four-dimensional conebeam CT reconstruction combining prior network and motion compensation	55
Design and hierarchical analysis of magnetic actuated robot: A governing equation based approach	55
Impact of workflow variability on image-based intracranial aneurysm hemodynamics	55
NIMEQ-SACNet: A novel self-attention precision medicine model for vision-threatening diabetic retinopathy using image data	55
Cervical cancer image analysis: Detection and segmentation using self-guided quantum GANs and musical chairs optimization	55
GeneDX-PBMC: An adversarial autoencoder framework for unlocking Alzheimer's disease biomarkers using blood single-cell RNA sequencing data	55
Identification of key candidate genes and biological pathways in neuropathic pain	54
Enclosing 95% confidence area and volume to center of pressure and center of mass in posturography using optimization algorithm and coordinate ascent methods	54
Modeling pulsed magneto-optical stimulation for controlled nanoparticle aggregation and hyperthermia in a non-Newtonain aqueous medium adjacent to a tumor	54
A mathematical model of tissue axial and radial diffusion in the microvasculature for intravascular microscopy and phosphorescence quenching data	54
Ce	54
Integrating local and global attention mechanisms for enhanced oral cancer detection and explainability	54
recruIT: A cloud-native clinical trial recruitment support system based on Health Level 7 Fast Healthcare Interoperability Resources (HL7 FHIR) and the Observational Medical Outcomes Partnership Commo	54
A multimodal deep learning framework for enzyme turnover prediction with missing modality	54
Multi-scale, multi-dimensional binocular endoscopic image depth estimation network	53
Analysis and design of antithetic proportional-integral-derivative biocontrol-systems with species dilution	53
Intelligent tuberculosis activity assessment system based on an ensemble of neural networks	53
Immunoinformatics-driven In silico vaccine design for Nipah virus (NPV): Integrating machine learning and computational epitope prediction	53
Analysis of power law fluid for nutritional transport in the human capillary	53
Individual thigh muscle and proximal femoral features predict displacement in femoral neck Fractures: An AI-driven CT analysis	52
Medical application of deep-learning-based head pose estimation from RGB image sequence	52
A modified reptile search algorithm for global optimization and image segmentation: Case study brain MRI images	52
Potential anti-liver cancer targets and mechanisms of kaempferitrin based on network pharmacology, molecular docking and experimental verification	52
Direct parametric reconstruction in dynamic PET using deep image prior and a novel parameter magnification strategy	52
A new diagnostic method and tool for cutaneous leishmaniasis based on artificial intelligence techniques	52
Patient-specific investigation into plaque rupture risk due to catheter tracking during TAVR	52
Combination of 2D and 3D nnU-Net for ground glass opacity segmentation in CT images of Post-COVID-19 patients	52