Computers in Biology and Medicine

Article	Citations
Two dimensional computational model coupling myoarchitecture-based lingual tissue mechanics with liquid bolus flow during oropharyngeal swallowing	650
EG-Unet: Edge-Guided cascaded networks for automated frontal brain segmentation in MR images	293
Wavelet coherence analysis of muscle coupling during reaching movement in stroke	285
Progress on the development of prediction tools for detecting disease causing mutations in proteins	255
ECLStat: A robust machine learning based visual imaging tool for electrochemiluminescence biosensing	245
Named entity recognition for de-identifying Spanish electronic health records	223
Latent representation learning for classification of the Doppler ultrasound images	221
Development and evaluation of a decision aid for HPV vaccination among adults aged 27–45 years old in the United States	211
Histopathology-based near-realistic arterial wall reconstruction of a patient-specific cerebral aneurysm for fluid-structure interaction studies	206
Interpretable prediction of drug-drug interactions via text embedding in biomedical literature	187
Artificial intelligence for identification of candidates for device-aided therapy in Parkinson's disease: DELIST-PD study	182
Optimizing convolutional neural networks for Chronic Obstructive Pulmonary Disease detection in clinical computed tomography imaging	169
Three-dimensional fluid–structure interaction modelling of the venous valve using immersed boundary/finite element method	167
Computational exploration of injection strategies for improving medicine distribution in the liver	166
Counting on AR: EEG responses to incongruent information with real-world context	163
DisorderUnetLM: Validating ProteinUnet for efficient protein intrinsic disorder prediction	162
Drug toxicity prediction model based on enhanced graph neural network	151
Automated detection of posterior urethral valves in voiding cystourethrography images: A novel AI-Based pipeline for enhanced diagnosis and classification	149
Automatic segmentation of intraluminal thrombosis of abdominal aortic aneurysms from CT angiography using a mixed-scale-driven multiview perception network (M2Net) model	143
Unraveling new avenues in pancreatic cancer treatment: A comprehensive exploration of drug repurposing using transcriptomic data	143
HOTGpred: Enhancing human O-linked threonine glycosylation prediction using integrated pretrained protein language model-based features and multi-stage feature selection approach	139
Novel interpretable Feature set extraction and classification for accurate atrial fibrillation detection from ECGs	138
Multi-granularity prior networks for uncertainty-informed patient-specific quality assurance	135
A graph neural network approach for predicting drug susceptibility in the human microbiome	124
S3T-Net: A nove	124

Editorial Board	122
The effects of aperture position and length in side-vented needles on root canal irrigation: A computational fluid dynamics study	118
Interpretable machine learning for dermatological disease detection: Bridging the gap between accuracy and explainability	118
A dual-encoder double concatenation Y-shape network for precise volumetric liver and lesion segmentation	117
GILEA: In silico phenome profiling and editing using GAN Inversion	114
Identification of new targets for glioblastoma therapy based on a DNA expression microarray	113
Single-cell RNA sequencing data analysis utilizing multi-type graph neural networks	111
DP-SSLoRA: A privacy-preserving medical classification model combining differential privacy with self-supervised low-rank adaptation	111
The identification of biomarkers for Alzheimer's disease using a systems biology approach based on lncRNA-circRNA-miRNA-mRNA ceRNA networks	109
Enhancing local representation learning through global–local integration with functional connectivity for EEG-based emotion recognition	109
Identification of anti-cancer organometallic compounds by inhibition of BCL-2/Bax interactions	107
Pan-vaccinomics approach towards a universal vaccine candidate against WHO priority pathogens to address growing global antibiotic resistance	106
DeepRF: A deep learning method for predicting metabolic pathways in organisms based on annotated genomes	105
Structural probing of HapR to identify potent phytochemicals to control Vibrio cholera through integrated computational approaches	104
In-silico heart model phantom to validate cardiac strain imaging	104
ECG classification via integration of adaptive beat segmentation and relative heart rate with deep learning networks	102
Enhancing sonothrombolysis outcomes with dual-frequency ultrasound: Insights from an in silico microbubble dynamics study	101
Genetic analysis from multiple cohorts implies causality between 2200 druggable genes, telomere length, and leukemia	100
Discrepancy-based diffusion models for lesion detection in brain MRI	100
From farm to pharma: Investigation of the therapeutic potential of the dietary plants Apium graveolens L., Coriandrum sativum, and Mentha longifolia, as AhR modulators for Immunotherapy	100
An intelligent garment for long COVID-19 real-time monitoring	99
Bi-level gene selection of cancer by combining clustering and sparse learning	98
Automated diagnosis of cardiovascular diseases from cardiac magnetic resonance imaging using deep learning models: A review	98
YMLA: A comparative platform to carry out functional enrichment analysis for multiple gene lists in yeast	98
US2Mask: Image-to-mask generation learning via a conditional GAN for cardiac ultrasound image segmentation	98
Thyroid region prior guided attention for ultrasound segmentation of thyroid nodules	97
A robust real-time deep learning based automatic polyp detection system	97
A novel P-QRS-T wave localization method in ECG signals based on hybrid neural networks	97
Evaluation of machine learning algorithms for health and wellness applications: A tutorial	96
Deep learning for predicting respiratory rate from biosignals	95
Multi-branch fusion auxiliary learning for the detection of pneumonia from chest X-ray images	95
Bayesian-based optimized deep learning model to detect COVID-19 patients using chest X-ray image data	94
ISW-LM: An intensive symptom weight learning mechanism for early COVID-19 diagnosis	94
Few-shot medical image segmentation using a global correlation network with discriminative embedding	94
Multi-input adaptive neural network for automatic detection of cervical vertebral landmarks on X-rays	94
Higher reproducibility of phase derived metrics from electrocardiographic imaging during atrial fibrillation in patients remaining in sinus rhythm after pulmonary vein isolation	93
Understanding the bias in machine learning systems for cardiovascular disease risk assessment: The first of its kind review	92
Breast cancer detection from thermal images using a Grunwald-Letnikov-aided Dragonfly algorithm-based deep feature selection method	91
Low-dose CT denoising using a Progressive Wasserstein generative adversarial network	91
A multidrug efflux protein in Mycobacterium tuberculosis; tap as a potential drug target for drug repurposing	91
Emotion recognition in EEG signals using deep learning methods: A review	90
Continuous online prediction of lower limb joints angles based on sEMG signals by deep learning approach	89
Diffusion-based conditional ECG generation with structured state space models	89
Joint optic disc and cup segmentation based on elliptical-like morphological feature and spatial geometry constraint	88
A feature-aware multimodal framework with auto-fusion for Alzheimer’s disease diagnosis	88
Machine learning integrated ensemble of feature selection methods followed by survival analysis for predicting breast cancer subtype specific miRNA biomarkers	88
JoCoRank: Joint correlation learning with ranking similarity regularization for imbalanced fetal brain age regression	88
Self-Distilled Supervised Contrastive Learning for diagnosis of breast cancers with histopathological images	87
Moving towards intelligent telemedicine: Computer vision measurement of human movement	87
A novel approach for COVID-19 Infection forecasting based on multi-source deep transfer learning	87

CT-based generation of synthetic-pseudo MR images with different weightings for human knee	86
Self-supervised learning-based cervical cytology for the triage of HPV-positive women in resource-limited settings and low-data regime	86
RDmaster: A novel phenotype-oriented dialogue system supporting differential diagnosis of rare disease	86
Liquid-liquid phase separation-related lncRNA prognostic signature and ZNF32-AS2 as a novel biomarker in hepatocellular carcinoma	86
Automatically recognize and segment morphological features of the 3D vertebra based on topological data analysis	85
Evolutionary warning system for COVID-19 severity: Colony predation algorithm enhanced extreme learning machine	84
Machine learning with a reduced dimensionality representation of comprehensive Pentacam tomography parameters to identify subclinical keratoconus	84
End-to-end learning with interpretation on electrohysterography data to predict preterm birth	84
An integrated in-silico Pharmaco-BioInformatics approaches to identify synergistic effects of COVID-19 to HIV patients	84
Computational studies evidenced the potential of steroidal lactone to disrupt surface interaction of SARS-CoV-2 spike protein and hACE2	84
VDA-RWLRLS: An anti-SARS-CoV-2 drug prioritizing framework combining an unbalanced bi-random walk and Laplacian regularized least squares	84
Graph-based relevancy-redundancy gene selection method for cancer diagnosis	84
Screening of potent phytochemical inhibitors against SARS-CoV-2 protease and its two Asian mutants	83
A meta-learning approach to improving radiation response prediction in cancers	83
Computation of a probabilistic and anisotropic failure metric on the aortic wall using a machine learning-based surrogate model	82
An evolutionary machine learning for multiple myeloma using Runge Kutta Optimizer from multi characteristic indexes	82
Native-resolution myocardial principal Eulerian strain mapping using convolutional neural networks and Tagged Magnetic Resonance Imaging	81
A bibliometric analysis of the cause of sudden unexplained death in forensic medicine: Research trends, hot spots and prospects	81
Automatic eczema classification in clinical images based on hybrid deep neural network	81
Dual-Stream Subspace Clustering Network for revealing gene targets in Alzheimer's disease	81
Exploring the cuproptosis-related molecular clusters in the peripheral blood of patients with amyotrophic lateral sclerosis	81
Editorial Board	81
P-ResUnet: Segmentation of brain tissue with Purified Residual Unet	80
Prediction of transport proteins from sequence information with the deep learning approach	80
Blood glucose detection based on Teager-Kaiser main energy of photoacoustic signal	79
Artificial intelligence for quality control of oscillometry measures	79
LSCS-Net: A lightweight skin cancer segmentation network with densely connected multi-rate atrous convolution	79
Modeling the protective role of human eyelashes against ultraviolet light exposure	78
A hybrid methodology for breast screening and cancer diagnosis using thermography	78
MACG-Net: Multi-axis cross gating network for deformable medical image registration	77
Biomechanical and histological changes associated with riboflavin ultraviolet-A-induced CXL with different irradiances in young human corneal stroma	77
Large-scale analysis of neural activity and connectivity from high-density electroencephalographic data	77
A novel machine learning model for efficacy prediction of immunotherapy-chemotherapy in NSCLC based on CT radiomics	77
Scalp surface estimation and head registration using sparse sampling and 3D statistical models	77
OPTICS: An interactive online platform for photosensory and bio-functional proteins in optogenetic systems	76
Czech medical coding assistant based on transformer networks	76
Diffuse tumors: Molecular determinants shared by different cancer types	76
Elicitation of fetal ECG from abdominal recordings using Blind Source Separation techniques and Robust Set Membership Affine Projection algorithm for signal quality enhancement	75
GPT-4 as a biomedical simulator	75
AI-Driven localization of all impacted teeth and prediction of winter angulation for third molars on panoramic radiographs: Clinical user interface design	73
An accurate unsupervised extraction of retinal vasculature using curvelet transform and classical morphological operators	73
GC-MS profiling of Bauhinia variegata major phytoconstituents with computational identification of potential lead inhibitors of SARS-CoV-2 Mpro	72
MR-Trans: MultiResolution Transformer for medical image segmentation	72
Prediction of viral pneumonia based on machine learning models analyzing pulmonary inflammation index scores	71
Potential inhibitors of the main protease of SARS-CoV-2 and modulators of arachidonic acid pathway: Non-steroidal anti-inflammatory drugs against COVID-19	71
Deep diagnostic agent forest (DDAF): A deep learning pathogen recognition system for pneumonia based on CT	70
Mathematical modeling of COVID-19 pandemic in India using Caputo-Fabrizio fractional derivative	69
MM-StackEns: A new deep multimodal stacked generalization approach for protein–protein interaction prediction	69
ECG segmentation algorithm based on bidirectional hidden semi-Markov model	69
SIL-Net: A Semi-Isotropic L-shaped network for dermoscopic image segmentation	69
Industry 4.0 technologies and their applications in fighting COVID-19 pandemic using deep learning techniques	69
A mask R-CNN based automatic assessment system for nail psoriasis severity	69
Enhanced depression detection from speech using Quantum Whale Optimization Algorithm for feature selection	68
Transfer learning-based approach for detecting COVID-19 ailment in lung CT scan	68
Automatic epileptic seizure detection via Stein kernel-based sparse representation	67
FFCM-MRF: An accurate and generalizable cerebrovascular segmentation pipeline for humans and rhesus monkeys based on TOF-MRA	67
MCPNET: Development of an interpretable deep learning model based on multiple conformations of the compound for predicting developmental toxicity	67
Explainable deep learning diagnostic system for prediction of lung disease from medical images	67
Alzheimer’s disease prediction algorithm based on de-correlation constraint and multi-modal feature interaction	67
Improved predictive diagnosis of diabetic macular edema based on hybrid models: An observational study	67
Pathogenicity classification of missense mutations based on deep generative model	67
Effect of tumor heterogeneity on enhancing drug delivery to vascularized tumors using thermo-sensitive liposomes triggered by hyperthermia: A multi-scale and multi-physics computational model	66
DRBpred: A sequence-based machine learning method to effectively predict DNA- and RNA-binding residues	66
CLCLSA: Cross-omics linked embedding with contrastive learning and self attention for integration with incomplete multi-omics data	66
Voxel representation of brain images inpainting via Regional Pixel Semantic Network and pyramidal attention AE - Quantile differential mechanism model	65
A method for predicting linear and conformational B-cell epitopes in an antigen from its primary sequence	65
SARS-CoV-2 NSP14 governs mutational instability and assists in making new SARS-CoV-2 variants	65
IVD fibrosis and disc collapse comprehensively aggravate vertebral body disuse osteoporosis and zygapophyseal joint osteoarthritis by posteriorly shifting the load transmission pattern	65
A multi-module algorithm for heartbeat classification based on unsupervised learning and adaptive feature transfer	65
Insights from explainable AI in oesophageal cancer team decisions	64
MetaCAE: Causal autoencoder with meta-knowledge transfer for brain effective connectivity estimation	64
Aberrant migration features in primary skin fibroblasts of Huntington's disease patients hold potential for unraveling disease progression using an image based machine learning tool	64
An efficient model for extracting respiratory and blood oxygen saturation data from photoplethysmogram signals by removing motion artifacts using heuristic-aided ensemble learning model	64
Enhancing targeted tumor treatment: A novel fuzzy logic framework for precision drug delivery strategy selection	63
FCSU-Net: A novel full-scale Cross-dimension Self-attention U-Net with collaborative fusion of multi-scale feature for medical image segmentation	63
Customized T-time inner sampling network with uncertainty-aware data augmentation strategy for multi-annotated lesion segmentation	63
Synthetic 3D full-body skeletal motion from 2D paths using RNN with LSTM cells and linear networks	63
Signal completion using generative adversarial networks for enhanced photoplethysmography measurement accuracy	63
Contrastive learning based method for X-ray and CT registration under surgical equipment occlusion	63
A novel graph neural network method for Alzheimer’s disease classification	62

Altruistic seagull optimization algorithm enables selection of radiomic features for predicting benign and malignant pulmonary nodules	62
Machine learning allows expert level classification of intraoperative motor evoked potentials during neurosurgical procedures	62
Brain-GCN-Net: Graph-Convolutional Neural Network for brain tumor identification	62
Characterization of cardiac resynchronization therapy response through machine learning and personalized models	62
Distributed management of patient data-sharing informed consents for clinical research	62
The sample locator: A federated search tool for biosamples and associated data in Europe using HL7 FHIR	62
Editorial Board	61
Virtual flow diverter deployment and embedding for hemodynamic simulations	61
GraphPro: An interpretable graph neural network-based model for identifying promoters in multiple species	61
XGraphCDS: An explainable deep learning model for predicting drug sensitivity from gene pathways and chemical structures	60
Enhancing cerebral arteriovenous malformation analysis: Development and application of patient-specific lumped parameter models based on 3D imaging data	60
Automated detection and classification of tumor histotypes on dynamic PET imaging data through machine-learning driven voxel classification	60
Context encoder transfer learning approaches for retinal image analysis	60
ℛSCZ: A Riemannian schizophrenia diagnosis framework based on the multiplexity of EEG-based dynamic functional connectivity patterns	60
An open-source, three-dimensional growth model of the mandible	59
Fine-grained food image classification and recipe extraction using a customized deep neural network and NLP	59
Using an artificial intelligence tool incorporating natural language processing to identify patients with a diagnosis of ANCA-associated vasculitis in electronic health records	59
Advances in understanding the specificity function of transporters by machine learning	59
SRTRP-Net: A multi-task learning network for segmentation and prediction of stereotactic radiosurgery treatment response in brain metastases	59
Optimized fuzzy K-nearest neighbor approach for accurate lung cancer prediction based on radial endobronchial ultrasonography	59
EEG power spectra parameterization and adaptive channel selection towards semi-supervised seizure prediction	59
Stratification of glioma based on stemness scores in bulk and single-cell transcriptomes	58
Enhancing gastric cancer early detection: A multi-verse optimized feature selection model with crossover-information feedback	58
The role of the extracellular matrix in the reduction of lateral force transmission in muscle bundles: A finite element analysis	58
Next-generation chemotherapy treatments based on black hole algorithms: From cancer remission to chronic disease management	57
Segmentation-based tracking of macrophages in 2D＋time microscopy movies inside a living animal	57
Predicting the effect of a combination drug therapy on the prostate tumor growth via an improvement of a direct radial basis function partition of unity technique for a diffuse-interface model	57
Choroidal Layer Analysis in OCT images via Ambiguous Boundary-aware Attention	57
ECLNet: Center localization of eye structures based on Adaptive Gaussian Ellipse Heatmap	57
Identification of secondary metabolites from Crescentia cujete as promising antibacterial therapeutics targeting type 2A topoisomerases through molecular dynamics simulation	56
MGCBFormer: The multiscale grid-prior and class-inter boundary-aware transformer for polyp segmentation	56
Superficial femoral artery calcification segmentation and detection in CT angiography using convolutional neural network	56
Utilization of AlphaFold models for drug discovery: Feasibility and challenges. Histone deacetylase 11 as a case study	56
A dynamical graph-based feature extraction approach to enhance mental task classification in brain–computer interfaces	56
Homologous recombination deficiency in triple-negative breast cancer: Multi-scale transcriptomics reveals distinct tumor microenvironments and limitations in predicting immunotherapy response	56
Hierarchical cumulative network for unsupervised medical image registration	56
Genome-wide transcriptomics and copy number profiling identify patient-specific CNV-lncRNA-mRNA regulatory triplets in colorectal cancer	55
Network pharmacology and LC-MS approachs to explore the active compounds and mechanisms of Yuanjiang decoction for treating bradyarrhythmia	55
Central moments multiple relaxation time LBM for hemodynamic simulations in intracranial aneurysms: An in-vitro validation study using PIV and PC-MRI	55
ILSHIP: An interpretable and predictive model for hypothyroidism	54
Self-supervised CT super-resolution with hybrid model	54
SAFNet: A deep spatial attention network with classifier fusion for breast cancer detection	54
Classifying tumor brain images using parallel deep learning algorithms	54
Diabetic retinopathy screening using deep learning for multi-class imbalanced datasets	53
Automatic heartbeat classification using S-shaped reconstruction and a squeeze-and-excitation residual network	53
ACP-check: An anticancer peptide prediction model based on bidirectional long short-term memory and multi-features fusion strategy	53
Multi-constraint point set registration with redundant point removal for the registration of coronary arteries	53
LayNet—A multi-layer architecture to handle imbalance in medical imaging data	53
A scalable artificial intelligence platform that automatically finds copy number variations (CNVs) in journal articles and transforms them into a database: CNV extraction, transformation, and loading	52
Comparison of machine learning techniques for the identification of human activities from inertial sensors available in a mobile device after the application of data imputation techniques	52
Extinction and stationary distribution of a stochastic COVID-19 epidemic model with time-delay	52
A diagnostic model for COVID-19 based on proteomics analysis	52
Towards similarity-based differential diagnostics for common diseases	52
Machine learning and network-based models to identify genetic risk factors to the progression and survival of colorectal cancer	52
A privacy-aware method for COVID-19 detection in chest CT images using lightweight deep conventional neural network and blockchain	52
COVID-19 diagnosis using state-of-the-art CNN architecture features and Bayesian Optimization	51
Performance evaluation of Emergency Department patient arrivals forecasting models by including meteorological and calendar information: A comparative study	51
Automatic detection of stroke lesion from diffusion-weighted imaging via the improved YOLOv5	51
Clinical stratification improves the diagnostic accuracy of small omics datasets within machine learning and genome-scale metabolic modelling methods	50
Identification of Key DNA methylation sites related to differentially expressed genes in Lung squamous cell carcinoma	50
Computational design of phage cocktails based on phage-bacteria infection networks	49
Prediction of qualitative antibiofilm activity of antibiotics using supervised machine learning techniques	49
Identification and computational analysis of mutations in SARS-CoV-2	49
EHDFL: Evolutionary hybrid domain feature learning based on windowed fast Fourier convolution pyramid for medical image classification	49
Numerical analysis of stenoses severity and aortic wall mechanics in patients with supravalvular aortic stenosis	49
Comprehensive analysis identifies ARHGEF6 as a potential prognostic and immunological biomarker in lung adenocarcinoma	49
Computational fluid dynamics comparison of impaired breathing function in French bulldogs with nostril stenosis and an examination of the efficacy of rhinoplasty	49
BAWGNet: Boundary aware wavelet guided network for the nuclei segmentation in histopathology images	48
Sparse non-convex regularization based explainable DBN in the analysis of brain abnormalities in schizophrenia	48
Unraveling the molecular crosstalk between Atherosclerosis and COVID-19 comorbidity	48
Fast instruments and tissues segmentation of micro-neurosurgical scene using high correlative non-local network	48
Non-standard bioinformatics characterization of SARS-CoV-2	48
A self-supervised COVID-19 CT recognition system with multiple regularizations	48
Computational screening of 645 antiviral peptides against the receptor-binding domain of the spike protein in SARS-CoV-2	48
Estimation of BMI from facial images using semantic segmentation based region-aware pooling	48
Simulation of a new respiratory phase sorting method for 4D-imaging using optical surface information towards precision radiotherapy	48
A novel self-learning framework for bladder cancer grading using histopathological images	47
Exploring the relationship between the dielectric properties and viability of human normal hepatic tissues from 10 Hz to 100 MHz based on grey relational analysis and BP neural network	47
Development of closed-loop modelling framework for adaptive respiratory pacemakers	47
An emotion recognition method based on EWT-3D–CNN–BiLSTM-GRU-AT model	47
Insights into the structural peculiarities of the N-terminal and receptor binding domains of the spike protein from the SARS-CoV-2 Omicron variant	47
LCSB-inception: Reliable and effective light-chroma separated branches for Covid-19 detection from chest X-ray images	46
2-HDCNN: A two-tier hybrid dual convolution neural network feature fusion approach for diagnosing malignant melanoma	46
An investigation into the hammer toe effects on the lower extremity mechanics and plantar fascia tension: A case for a vicious cycle and progressive damage	46
The Purkinje network plays a major role in low-energy ventricular defibrillation	46
3D finite-element modeling of air-cell-based cushions and buttock tissues during prolonged sitting	46
Single-channel EEG sleep staging based on data augmentation and cross-subject discrepancy alleviation	46
Multi-scale feature similarity-based weakly supervised lymphoma segmentation in PET/CT images	46
Uniqueness of inspiratory airflow patterns in a realistic rat nasal cavity	46
Identification of molecular mechanisms underlying the therapeutic effects of Celosia Cristata on immunoglobulin nephropathy	46
Accuracy of free-hand positioned patient specific implants (PSI) in primary reconstruction after inferior and/or medial orbital wall fractures	45
Predicting presumed serious infection among hospitalized children on central venous lines with machine learning	45
Multistage adaptive control strategy based on image contour data for autonomous endoscope navigation	45
Automated resection planning for bone tumor surgery	45
Multimodal analysis of electroencephalographic and electrooculographic signals	45