Clinica Chimica Acta

Papers
(The TQCC of Clinica Chimica Acta is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-05-01 to 2025-05-01.)
ArticleCitations
M062 Identification of biomarkers in patients with colorectal cancer in Kazakh population193
Analysis of the diagnostic and prognostic value of serum PAD2 in patients with sepsis in the intensive care unit135
Monitoring mutant KRAS in plasma cell-free DNA can predict disease progression in a patient with multiple myeloma: A case report131
T195 Plasma creatinine measurement in diabetic patients. Should we advocate the enzymatic method?121
T215 About a case: Crioaglutinine disease94
T223 Validation and clinical application of a novel platelet function analyzer (ANYSIS 200) in cardiology patients89
T258 Investigation of genetic biomarkers associated with low platelet count in normal karyotype acute myeloid leukemia78
W058 Salmonella infection among the suspected enteric fever patients76
W080 Nanoparticle-enhanced digitof for detection of e. coli directly from urine75
M102 Laboratory errors in clinical biochemistry: The quality of laboratory testing in B.P. Koirala institute of health sciences, Nepal71
The impact of neutrophil extracellular traps on deep venous thrombosis in patients with traumatic fractures70
M251 Potential reference measurement procedure— Determination of c-reactive protein in serum by isotope dilution mass spectrometry based on enzyme digestion64
T022 The role of antioxidant therapy in the symptomatic treatment of pancreatic cancer patients60
T040 Micrornas stimulate prostate cancer stem cell expansion by targeting genes of the apoptotic pathway60
T052 Tumor marker study in pleural fluid and tumor heterogeneity56
M003 Cytogenetic mechanisms of the aortic coarctation formation and their relationship with late postoperative complications54
Biological variation of thyroid function biomarkers over 24 hours52
W089 Emerging threat of biofilm producing MDR acinetobactercalcoaceticusbaumanniicomplex clinical isolates causing healthcare associated infections in a teaching hospital in Nepal52
W090 Effect of carbapenemase, qace, qace⊗1, and cepa genes on chlorhexidine sensitivity in clinical isolates of gram-negative bacteria with multiple resistance49
M208 Pakistan inherited metabolic disorders network (PAK-IMD-NET): Breaking silos and bringing synergies49
Diagnostic value of Serum Amyloid A, Interleukin-6 in gravidas with spontaneous preterm birth47
Editorial board member, Aims and Scope, Publication Info.46
Lipocalin2 as a useful biomarker for risk stratification in patients with acute cholangitis: A single-center prospective and observational study45
Quantitative analysis of soluble costimulatory molecules as potential diagnostic biomarkers for rheumatoid arthritis using LC-MS/MS in MRM mode42
W139 Molecular characterization of glucose 6-phosphate dehydrogenase deficiency among selected populations in malaria endemic area of Ethiopia42
Evaluation of a batched-extraction method for measurement of sirolimus, tacrolimus, and cyclosporine on the Architect i2000SR42
Development of exploratory algorithms to aid in risk of malignancy prediction of indeterminate pulmonary nodules42
W163 Effects of cassava processing methods on insulin index, glyceamic profile, glyceamic load and index of cassava (manihot esculeuta) meals in type 2 diabetes mellitus patients seen in Benue State U42
T134 Establishment of algorithms and threshold of thyroid stimulating immunoglobulin for diagnosis of Graves’ disease by data mining: A Chinese multicenter study40
T124 Hormonal biomarkers associated with in-hospital mortality in therapeutic hypothermia after cardiac arrest: A case series40
W264 A survey on RBC transfusion practice in Korea40
Diagnosis of patients with mucopolysaccharidosis type II via RNA sequencing37
T274 Natural killer cell subsets and phenotypic expression of markers of activation, maturation and associated with slow progression of HIV in HAART naïve HIV patients in Addis Ababa, Ethiopia37
M080 Tinea unguium, tinea cruris and tinea corporis caused by trichophyton rurbum in HIV patient: A case report37
M085 Determinants of systemic immunity to invasive salmonella infection in endemic settings36
“Extracellular Vesicle DNA: Advances and Applications as a Non-Invasive Biomarker in Disease Diagnosis and Treatment”35
T287 The change for qualitative balance of vascular endothelial growth factor-a may contribute to therapeutic efficacy for an anti-neutrophil cytoplasmic antibody associated vasculitis subtypes35
Hook-effect in MAGLUMI immunoassay for serum anti-GAD antibodies in neurological disorders: When “wrong” matrix is the right choice34
Evaluating the clinical effectiveness of cardiovascular precision diagnostics34
Comparative study of plasma clearance of iohexol at different injection doses34
Potentiometric urea biosensors34
Performance evaluation and validation of high-performance liquid chromatography method for the quantification vitamins A and E33
Assessment of an analysing system for the determination of NA+, K+, CL- and CA2+32
How did the COVID-19 pandemic impact drug trends?32
Determine the pharmacokinetics (half-life, volume of distribution and clearance) of AMB-FUBINACA in blood samples of rats using GC-MS/MS31
The increased sensitivity of the Xpert® Xpress assay in detecting SARS-COV-2, compared to the COBAS® assay, can be attributed to the nucleocapsid gene target31
Interference of hemolysis in urgent clinical biochemistry examinations analyzed on DxC 700 AU and access 229
Performance evaluation of the architect hepatitis c core antigen assay vs roche HCV DUO29
Pre-analytical issues in haemostasis29
Exploring artificial intelligence techniques for morphological analysis of digital images of peripheral blood cells: MC-80 versus HemaVision28
Laboratory-based study of newborn with intrauterine growth restriction28
Hypocalcemia and hypomagnesemia among patients with depression attending KFMMC-Dhahran-KSA27
Treating red blood cells with dithiothreitol can help eliminate daratumumab interference in blood compatibility tests (pretransfusion testing)27
Indeterminate results in quantiferon-TB gold plus testing: Possible explanation and predictive parameters27
Association of miRNA-126 cycle threshold values with the blood glucose concentration27
New insights in the newborn screening for methylmalonic aciduria in the Balearic Islands: Surprisingly high prevalence of CD320 gene mutation (transcobalamin receptor)27
Evaluation of beta glucan test using kinetic turbidimetric method on toxinometer MT-6500 for detection of invasive fungal infections in hospitalized patients26
The effect of calcium chloride on the release of platelet-derived growth factor-BB in the platelet-rich plasma products26
Improving of test utilization through modification of the electronic ordering system for blood zinc level26
Real-world data shows the effectiveness of a tetravalent vaccine against human papilloma virus types 16 and 18 in Chilean women26
Evaluation OF FGF-23 as a marker of mineral bone disease among newly diagnosed chronic kidney disease patients in a Nigerian hospital25
Evaluation of pre-analytical quality indicators by six sigma principle: Experience at a tertiary care hospital25
Unveiling liquid markers: The diagnostic revolution in early detection of pancreatic cancer through liquid biopsy25
Evaluation of metabolic and endocrine profiles in the elderly24
“Revolutionizing emergency care: A comparative analysis of comprehensive point-of-care test panels vs conventional laboratory processes in the critical care& emergency medicine”24
Seroprevalence and risk factors of toxoplasmosis among pregnant women in the M’saken region (Tunisia)24
Exploring the potency of Lamiaceae essential oils: Chemical composition and antibacterial efficacy against multidrug-resistant bacteri24
Immunoglobulin fragmentation challenges the interpretation of capillary protein electrophoresis results24
Association of ECM remodelling marker gene polymorphisms and their serum levels in acute and recurrent myocardial infarction24
Association of single nucleotide polymorphisms in eNOS gene with development of diabetic nephropathy: A case control study24
The reality of antimicrobial resistance (AMR) in Palestine and its impact on health and economy: A cross-sectional study in West Bank, Palestine23
Uric acid lithiasis in southern Tunisia23
A variant reclassification of SLC12A3 of Gitelman syndrome23
Study of the association between vitamin D and anti-mullerian hormone (AMH)23
Why do scientists call for action against vitamin D deficiency and what is behind the scene?23
Estimation of glomerular filtration rate with cystatin C in the evaluation of cardiovascular risk23
Not one-size-fits-all: The types and varieties of dtc tests and their potential harms23
Stability of arterial and venous gas samples stored for 20, 40 and 60 minutes after collection23
Principle of flow cytometry and issues in diagnosis22
Testosterone II (TSTII) and dimension VISTA® LOCI total testosterone (TTST) immunoassays meet the CDC host certification requirements for more than four years22
Antibiotic resistance profile of enterobacteriaceae isolated from infected hemodialysis catheters22
Thyroid profile abnormalities among patients tested at the Nairobi Hospital Laboratory, Kenya22
Raman spectroscopic analysis of urine combined with machine learning identifies life-threatening inborn errors of metabolism22
Strategy to improve the turn around time (TAT) for stat samples in clinical laboratories22
Cardiorenal syndrome and diabetes mellitus in indonesian population22
A system troubleshooting for HIV-1 drug resistance genotyping amplification rate failure at Ethiopian public health institute HIV laboratory22
Next step in predictive medicine: New serum biomarkers to predict acute stroke mortality22
Identification of cell cycle-related hub genes HMMR AND CDC25C for prognosis of head and neck squamous cell carcinoma through co-expression network analysis21
Effects of obesity on liver function in children21
Comparison of various E-GFR equations in estimating glomerular filtration rate in Indians21
Changes in nonalcoholic fatty liver disease and M2BPHI due to lifestyle intervention in primary healthcare21
Detection of mycobacterium tuberculosis and rifampicin resistance with Xpert® MTB/RIF analysis in a tertiary hospital21
Interference in the detection of HBA1C: Detection of abnormal HB presence21
Hematological malignancies: Analysis of complete blood count (CBC) and myelogram results in the Hematology Laboratory of Hedi Chaker Hospital Sfax (South Tunisia)21
GLCCI1 gene body methylation in peripheral blood is associated with asthma and asthma severity20
Evaluation of thrombin generation assay in factor XI deficiency20
Unexpectedly low hemoglobin A1c in a patient with chronic lymphocytic leukemia20
Serum metabolomic profile of myasthenia gravis and potential values as biomarkers in disease monitoring20
Epigenetics of Diabetes: A bioinformatic approach19
The liver and blood cells are responsible for creatine kinase clearance in blood Circulation: A retrospective study among different human diseases19
Functional characterization of novel variants found in patients with suspected Fabry disease19
MicroRNA regulators of vascular pathophysiology in chronic kidney disease19
Identification of of a PAX2 mutation from maternal mosaicism causes recurrent renal disorder in siblings19
Evaluating the effect of gestational diabetes mellitus on macrosomia based on the characteristics of oral glucose tolerance test19
Exploring strategies to rapidly identify false positives in high-sensitivity cardiac troponin I assay: A prospective study18
Irisin in atherosclerosis18
Editorial Board18
An accurate measurement method for serum homocysteine measurement by ID-LC/MS/MS and the application of external quality assessment18
Editorial Board18
Blood biomarkers for Alzheimer’s disease with the Lumipulse automated platform: Age-effect and clinical value interpretation18
Exosome biosensors for detection of liver cancer18
Electrochemical biosensors for enhanced detection of diabetes mellitus18
Serum Gas6 contributes to clinical outcome after aneurysmal subarachnoid hemorrhage: A prospective cohort study17
Circulating calprotectin as biomarker in neutrophil-related inflammation: Pre-analytical recommendations and reference values according to sample type17
The pentraxin family in autoimmune disease17
Recent advances in lateral flow assays for MicroRNA detection17
The value of serum tumor-associated autoantibodies in screening and diagnosis of gastric cancer17
Targeted next-generation sequencing reveals novel and known variants of thrombophilia associated genes in Saudi patients with venous thromboembolism17
SLC37A4-CDG: New biochemical insights for an emerging congenital disorder of glycosylation with major coagulopathy17
Editorial Board17
Resistin and omentin in breast cancer: A systematic review and meta-analysis17
Untargeted metabolomics analysis of the plasma metabolic signature of moderate-to-severe acne17
Simultaneous determination of multiple urine biomarkers for kidney injury using SPE combined with LC-MS/MS17
Comparison of digital PCR systems for the analysis of liquid biopsy samples of patients affected by lung and colorectal cancer16
miRNA-based electrochemical biosensors for ovarian cancer16
Similar Ferroportin Q248H polymorphism prevalence in patients with Plasmodium falciparum malaria and control subjects in the low-endemic setting of Botswana16
The value of serum glial fibrillary acidic protein as a biomarker of astrogliosis in different neurological diseases16
Nanoparticle electrochemical biosensors for virus detection16
Quantification of choline in serum and plasma using a clinical nuclear magnetic resonance analyzer16
Clinical laboratory evaluation of COVID-1916
Integrating multiplex PCR in fever clinics for acute respiratory pathogen-specific diagnosis16
Development and application of a novel aldehyde nanoparticle-based amplified luminescent proximity homogeneous assay for rapid quantitation of pancreatic stone protein16
Metabolomics identifies metabolite markers in plasma and extracellular vesicles within plasma in patients with asthma16
Targeted plasma proteomic analysis uncovers a high-performance biomarker panel for early diagnosis of gastric cancer16
Identification of a novel plasma metabolite panel as diagnostic biomarker for hepatocellular carcinoma16
Plasma lipidomics reveals potential lipid markers for the prediction of delayed neurocognitive recovery after cardiac surgery with cardiopulmonary bypass16
A novel variant of the POLR3A gene in a patient with hypomyelinating POLR3-related leukodystrophy15
Biological variation of methylmalonic acid in urine in spanish population15
Quality management, ethical considerations, and emerging challenges in genomics and biobanking: A comprehensive review15
Pediatric reference values of NT-proBNP and Galectin-3 based on a French cohort15
The role of tubulointerstitial markers in differential diagnosis and prognosis in patients with type 2 diabetes and biopsy proven diabetic kidney disease15
At-admission HbA1c levels in hospitalized COVID-19 participants with and without known diabetes15
A retrospective analysis of 1600 infertility patients with azoospermia and severe oligozoospermia15
Clinical implications of opioid parent-metabolite ratios15
Comment on ‘The diagnostic value of interleukin-36 cytokines in pleural effusions of varying etiologies’15
PIWI-interacting RNAs and PIWI proteins in diabetes and cardiovascular disease: Molecular pathogenesis and role as biomarkers14
Comparison of clot waveform analysis with or without adjustment between prothrombin time and activated partial thromboplastin time assays to assess in vitro effects of direct oral anticoagulants14
The clinical validation of a dried blood spot method for simultaneous measurement of cyclosporine A, tacrolimus, creatinine, and hematocrit14
Evaluation of iron metabolism in hospitalized COVID-19 patients14
Analysis of gene mutation characteristics and its correlation with prognosis in patients with myelodysplastic syndromes14
Association between apolipoprotein B/A1 and the risk of metabolic dysfunction associated fatty liver disease according to different lipid profiles in a Chinese population: A cross-sectional study14
Associations between polycythemia and cardiometabolic risk factors in middle-aged men14
Evaluating the utility of using glycated albumin in diagnosing dysglycemia among Saudis- A pilot study13
The association of siMS and siMS risk scores with risk factors for cardiovascular events in university students with metabolic syndrome13
Evaluating the efficacy of a long-read sequencing-based approach in the clinical diagnosis of neonatal congenital adrenocortical hyperplasia13
Enhancing breast cancer treatment through pharmacogenomics: A narrative review13
Study of the impact of ClinGen Revisions on ACMG/AMP variant semi-automatic classification for Rare Diseases diagnosis13
Relationships among maternal monosomy X mosaicism, maternal trisomy, and discordant sex chromosome aneuploidies13
Metabolomic profiling of serum and tongue coating of pregnant women with intrahepatic cholestasis in pregnancy13
Application of neutrophil-to-lymphocyte ratio in the diagnosis of complicated pediatric appendicitis13
Distance changes of lymphocyte quantity and function in patients with COVID-1913
MicroRNA and cyclooxygenase-2 in breast cancer13
Noninvasive fecal testing for colorectal cancer13
Analysis of two intestinal bacterial metabolites (trimethylamine N-oxide and phenylacetylglutamine) in human serum samples of patients with T2DM and AMI using a liquid chromatography tandem mass spect13
Cytomegalovirus antigen-specific multi-cytokine immune responses in patients with rheumatic diseases under different cytomegalovirus infection status: A case-control study13
Procalcitonin and transferrin as a survival markers of patients with COVID-1913
Advantages of the implementation of a second-tier test strategy in the newborn screening13
Overweight and obesity: The weight of genes13
Leveraging machine learning to improve current diagnostic algorithms and laboratory stewardship13
Targeting tumour markers in ovarian cancer treatment13
Proteomics of neuropsychiatric disorders13
A CD3G homozygous pathogenic variant in a Chinese child with lupus-like disease, autoimmune thyroiditis and immunodeficiency13
Large-scale retrospective analyses of the effect of iron deficiency anemia on hemoglobin A1c concentrations13
Non-invasive fetal RHD genotyping in d- (RH:-1) patients with RHD genomic sequences: retrospective study over 11 years13
Novel biomarkers to improve diagnosis and monitor prognosis12
Neonatal myofibrillar myopathy type II associated with biallelic UNC-45B gene novel mutation and perinatal myasthenia as the core phenotype: A case report12
Editorial Board12
The association between the PON1 genes rs662 and rs854560 and the metabolic syndrome in patients with obesity12
Brucella outbreak linked to ice cream: A Lebanese case series12
Liaison MeMed BV: A new approach for a quicker diagnosis between viral and bacterial infections in a cohort of pediatric patients12
Study of teratozoospermia in our population through analysis of seminal fluid in the assisted human reproduction unit of a Spanish referral hospital12
Evaluation of the performance of biochemical ratios and albumin’s gradient in the etiological exploration of ascitic fluid12
The role of laboratory diagnostics in determining the physical health of psychiatric inpatients12
Enhancing enteric pathogen detection: implementation and impact of multiplex PCR for improved diagnosis and surveillance12
Revolutionizing cell-based analyses: An electrochemical analysis platform with integrated incubator capabilities12
A novel KCNQ2 missense variant in non-syndromic intellectual disability causes mild gain-of-function of Kv7.2 channel12
Plasma cellular prion protein concentrations correlate with severity and prognosis of aneurysmal subarachnoid hemorrhage12
Estimation of FGF-23 level in patients with chronic kidney disease with or without vitamin D supplementation12
Association of HIV-1 Nef polymorphisms with coronary artery disease in HIV-positive patients12
Clinical performance evaluation of smartchek SARS-COV-2 detection kit and smartchek SARS-COV-2 fast detection kit for detection of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) in saliv12
Waste management in clinical laboratories12
Bacteriological profile and antimicrobial susceptibility patterns of organisms responsible for blood stream infections in intensive care unit patients12
Mild-to-moderate COVID-19 may affect nervous system function in convalescents12
Strategic collaboration to address nitrous oxide challenges: Establishment of an international consortium of experts12
Performance verification and reference interval establishment of serum/plasma aldosterone by a novel “sandwich” chemiluminescent immunoassay12
M200 Evaluation of eight commercially available clinical chemistry assays on the ALINITY® C system12
W157 Prostaglandin-D-synthase levels in cerebrospinal fluid associated with altered tau proteins in patients with suspected Alzheimer’s disease12
Challenges with sweat testing – A quality improvement initiative12
Risk stratification and predictive value of serum sodium fluctuation for adverse prognosis in acute coronary syndrome patients12
Apolipoprotein C-III mucin core 2 O-Linked glycoforms: Hiding in plain sight12
Serologic profile of individuals who contracted COVID-19 despite triple vaccination12
Utility of serum indices for predicting liver fibrosis12
Impact of CSF collection volume in the accuracy of Alzheimer’s disease biomarker results12
Stool antigen testing and serology’s accuracy in identifying helicobacter pylori infections in suspected patients11
Fragmentation of human cardiac troponin T after acute myocardial infarction11
Electrochemical biosensors in early leukemia detection11
A multi-test planning model for risk based statistical quality control strategies11
T257 Blood coagulation testing and hematological features of thalassemia carriers in pregnant11
Laboratory medicine residents in France − highly qualified, scarcely mobile11
Serum concentration of placental growth factor in pregnancy screening for placental dysfunction and low molecular weight heparin treatment11
T181 Establishment of influence factors and ageing models for thyroid hormones in the elderly using real-world big data11
T129 Stability of arterial blood gases (ABG)11
Association of lipoprotein(a) with left ventricular hypertrophy in patients with new-onset acute myocardial infarction: A large cross-sectional study11
T017 Analytical and clinical assessment of prostate specific antigen by chemiluminescence HISCL-5000 immunoassay11
Clinical and genetic investigation in patients with permanent congenital hypothyroidism11
M052 Evaluation of extracellular fatty acid synthase and copeptin in obesity induced insulin resistance and metabolic syndrome11
Exploring the key factors of schizophrenia relapse by integrating LC-MS/1H NMR metabolomics and weighted correlation network analysis11
Leptin in skin disease modulation11
Diagnostic value of combining tumor and inflammatory biomarkers in detecting common cancers in Korea11
W224 Is there a relationship between seminal zinc concentration and sperm quality in overweight men?11
Lean adolescents with insulin resistance display higher angiopoietin like protein 3, ApoC-III and chylomicron remnant dyslipidemia11
Correlation between the levels of serum C-reactive protein and plasma glycated HbA1c in diabetic patients and non-diabetic individuals in the western parts of Nepal11
T021 Nagalase – New laboratory test for the discovery of malignancy and some serious viral diseases11
Emergency severity level-3 patient flow based on point-of-care testing improves patient outcomes11
T170 Three cases of endocrine immune-related adverse events caused by immune checkpoint inhibitor therapy11
M122 Sample rejection of mixed body fluids for CSF identification – The utility of fluid protein concentration11
Editorial board member, Aims and Scope, Publication Info.11
W055 Serum erythroferrone in chronic kidney disease patients11
T104 An accuracy of blood glucose obtained from glucose meter [LDQUO]Standard Gluconavii® GDH Blood Glucose Meter[RDQUO] by testing with arterial and neonatal blood samples11
The biomarkers of oxidative stress – An effective tool for diagnosing COVID-19 patients and convalescents11
What do we need to obtain high quality circulating tumor DNA (ctDNA) for routine diagnostic test in oncology? – Considerations on pre-analytical aspects by the IFCC workgroup cfDNA11
Normal transferrin patterns in congenital disorders of glycosylation with Golgi homeostasis disruption: apolipoprotein C-III at the rescue!11
HDL subfractions determined by microfluidic chip electrophoresis predict the vulnerability of intracranial plaque: A HRMRI study11
LIS requirements for laboratory management11
TQ-Oxime derivative: A promising therapeutic agent for U87 glioma cells assessment of cytotoxic and apoptotic properties11
Deficiency or sufficiency? A five-year analysis of calcidiol levels across age groups in the Spanish population11
T201 The liver enzymes in patients with cirrhosis and hepatocellular carcinoma (HCC)11
Seroprevalence of antinuclear antibodies in patients with Hepatitis B11
W226 NGS-based pipeline for routine non-invasive preimplantation genetic assessment in IVF11
T079 High sensitive troponin assays in differentiating acute coronary syndrome from healthy individuals11
Urinary neutrophil gelatinase-associated lipocalin was a predictor from the day after intensive care unit entry, but not on the day of intensive care unit entry11
W014 About a case of rhabdomyolysis in a 7 year-old child secondary to a deficiency of very long-chain acyl-coa dehydrogenase (VLCAD)11
Use of point of care (POCT) c-reactive protein (CRP) to support antibiotic prescribing in primary care – Are they good enough? A review of performance on the Weqas POCT CRP programme11
Creatine and creatinine quantified using nuclear magnetic resonance: A method validation study and clinical associations between circulating creatine and fatigue in kidney transplant recipients10
Molecular diagnosis for growth hormone deficiency in Chinese children and adolescents and evaluation of impact of rare genetic variants on treatment efficacy of growth hormone10
Acute aluminum phosphide poisoning: The menace of phosphine exposure10
Assessment of a novel point-of-care system for chemistry panel testing10
Angiopoietin-like proteins in atherosclerosis10
Seminal plasma proteomics as putative biomarkers for male infertility diagnosis10
A deep learning-based system for assessment of serum quality using sample images10
0.039624929428101