Clinica Chimica Acta

Papers
(The TQCC of Clinica Chimica Acta is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)
ArticleCitations
Evaluating the clinical effectiveness of cardiovascular precision diagnostics254
Performance evaluation and validation of high-performance liquid chromatography method for the quantification vitamins A and E158
How did the COVID-19 pandemic impact drug trends?106
Assessment of an analysing system for the determination of NA+, K+, CL- and CA2+99
Determine the pharmacokinetics (half-life, volume of distribution and clearance) of AMB-FUBINACA in blood samples of rats using GC-MS/MS89
The increased sensitivity of the Xpert® Xpress assay in detecting SARS-COV-2, compared to the COBAS® assay, can be attributed to the nucleocapsid gene target84
Effects of obesity on liver function in children84
Interference of hemolysis in urgent clinical biochemistry examinations analyzed on DxC 700 AU and access 277
Pre-analytical issues in haemostasis69
Performance evaluation of the architect hepatitis c core antigen assay vs roche HCV DUO65
Laboratory-based study of newborn with intrauterine growth restriction61
Exploring artificial intelligence techniques for morphological analysis of digital images of peripheral blood cells: MC-80 versus HemaVision58
New insights in the newborn screening for methylmalonic aciduria in the Balearic Islands: Surprisingly high prevalence of CD320 gene mutation (transcobalamin receptor)56
Indeterminate results in quantiferon-TB gold plus testing: Possible explanation and predictive parameters54
Hypocalcemia and hypomagnesemia among patients with depression attending KFMMC-Dhahran-KSA49
Association of miRNA-126 cycle threshold values with the blood glucose concentration49
Treating red blood cells with dithiothreitol can help eliminate daratumumab interference in blood compatibility tests (pretransfusion testing)46
The effect of calcium chloride on the release of platelet-derived growth factor-BB in the platelet-rich plasma products45
Improving of test utilization through modification of the electronic ordering system for blood zinc level44
Evaluation of beta glucan test using kinetic turbidimetric method on toxinometer MT-6500 for detection of invasive fungal infections in hospitalized patients44
Unveiling liquid markers: The diagnostic revolution in early detection of pancreatic cancer through liquid biopsy40
Evaluation of pre-analytical quality indicators by six sigma principle: Experience at a tertiary care hospital39
Evaluation OF FGF-23 as a marker of mineral bone disease among newly diagnosed chronic kidney disease patients in a Nigerian hospital38
Immunoglobulin fragmentation challenges the interpretation of capillary protein electrophoresis results37
Seroprevalence and risk factors of toxoplasmosis among pregnant women in the M’saken region (Tunisia)37
Evaluation of metabolic and endocrine profiles in the elderly37
Association of ECM remodelling marker gene polymorphisms and their serum levels in acute and recurrent myocardial infarction35
Association of single nucleotide polymorphisms in eNOS gene with development of diabetic nephropathy: A case control study33
“Revolutionizing emergency care: A comparative analysis of comprehensive point-of-care test panels vs conventional laboratory processes in the critical care& emergency medicine”33
Exploring the potency of Lamiaceae essential oils: Chemical composition and antibacterial efficacy against multidrug-resistant bacteri33
Stability of arterial and venous gas samples stored for 20, 40 and 60 minutes after collection32
Estimation of glomerular filtration rate with cystatin C in the evaluation of cardiovascular risk32
A variant reclassification of SLC12A3 of Gitelman syndrome32
Uric acid lithiasis in southern Tunisia31
Why do scientists call for action against vitamin D deficiency and what is behind the scene?31
Not one-size-fits-all: The types and varieties of dtc tests and their potential harms30
The reality of antimicrobial resistance (AMR) in Palestine and its impact on health and economy: A cross-sectional study in West Bank, Palestine30
Study of the association between vitamin D and anti-mullerian hormone (AMH)30
Testosterone II (TSTII) and dimension VISTA® LOCI total testosterone (TTST) immunoassays meet the CDC host certification requirements for more than four years29
A system troubleshooting for HIV-1 drug resistance genotyping amplification rate failure at Ethiopian public health institute HIV laboratory29
Cardiorenal syndrome and diabetes mellitus in indonesian population29
Strategy to improve the turn around time (TAT) for stat samples in clinical laboratories29
Principle of flow cytometry and issues in diagnosis29
Raman spectroscopic analysis of urine combined with machine learning identifies life-threatening inborn errors of metabolism28
Thyroid profile abnormalities among patients tested at the Nairobi Hospital Laboratory, Kenya28
Next step in predictive medicine: New serum biomarkers to predict acute stroke mortality28
Antibiotic resistance profile of enterobacteriaceae isolated from infected hemodialysis catheters27
Detection of mycobacterium tuberculosis and rifampicin resistance with Xpert® MTB/RIF analysis in a tertiary hospital27
Editorial Board26
Changes in nonalcoholic fatty liver disease and M2BPHI due to lifestyle intervention in primary healthcare26
Editorial Board26
Hematological malignancies: Analysis of complete blood count (CBC) and myelogram results in the Hematology Laboratory of Hedi Chaker Hospital Sfax (South Tunisia)26
Aptamer-based electrochemical biosensors for progesterone detection: Advancing point-of-care diagnostics26
Editorial Board25
Identification of cell cycle-related hub genes HMMR AND CDC25C for prognosis of head and neck squamous cell carcinoma through co-expression network analysis25
Comparison of various E-GFR equations in estimating glomerular filtration rate in Indians25
Targeted plasma proteomic analysis uncovers a high-performance biomarker panel for early diagnosis of gastric cancer25
Interference in the detection of HBA1C: Detection of abnormal HB presence25
An accurate measurement method for serum homocysteine measurement by ID-LC/MS/MS and the application of external quality assessment24
Plasma protein biomarkers for long COVID-19: Predictors of symptom severity and mortality risk24
Urinary iodine testing practices in China: Results of the 5-year external quality assessment program24
Plasma lipidomics reveals potential lipid markers for the prediction of delayed neurocognitive recovery after cardiac surgery with cardiopulmonary bypass24
M085 Determinants of systemic immunity to invasive salmonella infection in endemic settings23
Metabolomics identifies metabolite markers in plasma and extracellular vesicles within plasma in patients with asthma23
Evaluation of thrombin generation assay in factor XI deficiency23
GLCCI1 gene body methylation in peripheral blood is associated with asthma and asthma severity23
T287 The change for qualitative balance of vascular endothelial growth factor-a may contribute to therapeutic efficacy for an anti-neutrophil cytoplasmic antibody associated vasculitis subtypes23
T274 Natural killer cell subsets and phenotypic expression of markers of activation, maturation and associated with slow progression of HIV in HAART naïve HIV patients in Addis Ababa, Ethiopia23
W080 Nanoparticle-enhanced digitof for detection of e. coli directly from urine22
Unexpectedly low hemoglobin A1c in a patient with chronic lymphocytic leukemia22
Evaluation of a batched-extraction method for measurement of sirolimus, tacrolimus, and cyclosporine on the Architect i2000SR22
W058 Salmonella infection among the suspected enteric fever patients22
Biological variation of thyroid function biomarkers over 24 hours22
Serum Gas6 contributes to clinical outcome after aneurysmal subarachnoid hemorrhage: A prospective cohort study22
T134 Establishment of algorithms and threshold of thyroid stimulating immunoglobulin for diagnosis of Graves’ disease by data mining: A Chinese multicenter study22
T052 Tumor marker study in pleural fluid and tumor heterogeneity21
W139 Molecular characterization of glucose 6-phosphate dehydrogenase deficiency among selected populations in malaria endemic area of Ethiopia21
M003 Cytogenetic mechanisms of the aortic coarctation formation and their relationship with late postoperative complications21
W089 Emerging threat of biofilm producing MDR acinetobactercalcoaceticusbaumanniicomplex clinical isolates causing healthcare associated infections in a teaching hospital in Nepal21
M251 Potential reference measurement procedure— Determination of c-reactive protein in serum by isotope dilution mass spectrometry based on enzyme digestion21
Untargeted metabolomics analysis of the plasma metabolic signature of moderate-to-severe acne21
Development of exploratory algorithms to aid in risk of malignancy prediction of indeterminate pulmonary nodules21
W090 Effect of carbapenemase, qace, qace⊗1, and cepa genes on chlorhexidine sensitivity in clinical isolates of gram-negative bacteria with multiple resistance21
T223 Validation and clinical application of a novel platelet function analyzer (ANYSIS 200) in cardiology patients21
T258 Investigation of genetic biomarkers associated with low platelet count in normal karyotype acute myeloid leukemia21
M102 Laboratory errors in clinical biochemistry: The quality of laboratory testing in B.P. Koirala institute of health sciences, Nepal20
T124 Hormonal biomarkers associated with in-hospital mortality in therapeutic hypothermia after cardiac arrest: A case series20
W163 Effects of cassava processing methods on insulin index, glyceamic profile, glyceamic load and index of cassava (manihot esculeuta) meals in type 2 diabetes mellitus patients seen in Benue State U20
Functional characterization of novel variants found in patients with suspected Fabry disease20
T215 About a case: Crioaglutinine disease20
M080 Tinea unguium, tinea cruris and tinea corporis caused by trichophyton rurbum in HIV patient: A case report20
T022 The role of antioxidant therapy in the symptomatic treatment of pancreatic cancer patients20
M208 Pakistan inherited metabolic disorders network (PAK-IMD-NET): Breaking silos and bringing synergies20
W264 A survey on RBC transfusion practice in Korea20
Identification of of a PAX2 mutation from maternal mosaicism causes recurrent renal disorder in siblings20
M062 Identification of biomarkers in patients with colorectal cancer in Kazakh population20
T040 Micrornas stimulate prostate cancer stem cell expansion by targeting genes of the apoptotic pathway20
Evaluating the effect of gestational diabetes mellitus on macrosomia based on the characteristics of oral glucose tolerance test20
T195 Plasma creatinine measurement in diabetic patients. Should we advocate the enzymatic method?20
Editorial board member, Aims and Scope, Publication Info.20
Boron-doped diamond electrochemical biosensors19
Assay-Dependent Effects of EDTA Contamination on Magnesium and Iron19
The pentraxin family in autoimmune disease19
Diagnosis of patients with mucopolysaccharidosis type II via RNA sequencing19
Non-coding RNA biomarkers in Alzheimer’s disease19
Serum metabolomic profile of myasthenia gravis and potential values as biomarkers in disease monitoring19
Comparison of digital PCR systems for the analysis of liquid biopsy samples of patients affected by lung and colorectal cancer19
Evaluation of a rapid immunochromatographic diagnostic test for heparin-induced thrombocytopenia: validation of delayed test and whole blood test19
Development and application of a novel aldehyde nanoparticle-based amplified luminescent proximity homogeneous assay for rapid quantitation of pancreatic stone protein19
Resistin and omentin in breast cancer: A systematic review and meta-analysis19
Epigenetics of Diabetes: A bioinformatic approach19
Lipocalin2 as a useful biomarker for risk stratification in patients with acute cholangitis: A single-center prospective and observational study19
The value of serum tumor-associated autoantibodies in screening and diagnosis of gastric cancer18
Diagnostic value of Serum Amyloid A, Interleukin-6 in gravidas with spontaneous preterm birth18
MicroRNA regulators of vascular pathophysiology in chronic kidney disease18
Identification of a novel plasma metabolite panel as diagnostic biomarker for hepatocellular carcinoma18
The liver and blood cells are responsible for creatine kinase clearance in blood Circulation: A retrospective study among different human diseases18
Monitoring mutant KRAS in plasma cell-free DNA can predict disease progression in a patient with multiple myeloma: A case report18
Electrochemical biosensors for enhanced detection of diabetes mellitus18
Blood biomarkers for Alzheimer’s disease with the Lumipulse automated platform: Age-effect and clinical value interpretation18
Comparative study of plasma clearance of iohexol at different injection doses18
Analysis of the diagnostic and prognostic value of serum PAD2 in patients with sepsis in the intensive care unit18
Integrating multiplex PCR in fever clinics for acute respiratory pathogen-specific diagnosis18
Exploring strategies to rapidly identify false positives in high-sensitivity cardiac troponin I assay: A prospective study17
The value of serum glial fibrillary acidic protein as a biomarker of astrogliosis in different neurological diseases17
Potentiometric urea biosensors17
Hook-effect in MAGLUMI immunoassay for serum anti-GAD antibodies in neurological disorders: When “wrong” matrix is the right choice17
Real-world data shows the effectiveness of a tetravalent vaccine against human papilloma virus types 16 and 18 in Chilean women17
Nanoparticle electrochemical biosensors for virus detection17
Simultaneous determination of multiple urine biomarkers for kidney injury using SPE combined with LC-MS/MS17
miRNA-based electrochemical biosensors for ovarian cancer17
Inflammation in maple syrup urine disease17
Quantification of choline in serum and plasma using a clinical nuclear magnetic resonance analyzer17
Quantitative analysis of soluble costimulatory molecules as potential diagnostic biomarkers for rheumatoid arthritis using LC-MS/MS in MRM mode17
Similar Ferroportin Q248H polymorphism prevalence in patients with Plasmodium falciparum malaria and control subjects in the low-endemic setting of Botswana17
Exosome biosensors for detection of liver cancer17
Recent advances in lateral flow assays for MicroRNA detection17
TQ-Oxime derivative: A promising therapeutic agent for U87 glioma cells assessment of cytotoxic and apoptotic properties16
Correlation between the levels of serum C-reactive protein and plasma glycated HbA1c in diabetic patients and non-diabetic individuals in the western parts of Nepal16
“Extracellular Vesicle DNA: Advances and Applications as a Non-Invasive Biomarker in Disease Diagnosis and Treatment”16
The biomarkers of oxidative stress – An effective tool for diagnosing COVID-19 patients and convalescents16
Deficiency or sufficiency? A five-year analysis of calcidiol levels across age groups in the Spanish population16
Use of point of care (POCT) c-reactive protein (CRP) to support antibiotic prescribing in primary care – Are they good enough? A review of performance on the Weqas POCT CRP programme16
Comment on ‘The diagnostic value of interleukin-36 cytokines in pleural effusions of varying etiologies’16
Seroprevalence of antinuclear antibodies in patients with Hepatitis B16
Laboratory medicine residents in France − highly qualified, scarcely mobile16
Stool antigen testing and serology’s accuracy in identifying helicobacter pylori infections in suspected patients16
Biological variation of methylmalonic acid in urine in spanish population16
Serum concentration of placental growth factor in pregnancy screening for placental dysfunction and low molecular weight heparin treatment16
Neonatal myofibrillar myopathy type II associated with biallelic UNC-45B gene novel mutation and perinatal myasthenia as the core phenotype: A case report15
Exploring the key factors of schizophrenia relapse by integrating LC-MS/1H NMR metabolomics and weighted correlation network analysis15
T170 Three cases of endocrine immune-related adverse events caused by immune checkpoint inhibitor therapy15
A multi-test planning model for risk based statistical quality control strategies15
Editorial Board15
T021 Nagalase – New laboratory test for the discovery of malignancy and some serious viral diseases15
Clinical and genetic investigation in patients with permanent congenital hypothyroidism15
Evaluation of iron metabolism in hospitalized COVID-19 patients15
T104 An accuracy of blood glucose obtained from glucose meter [LDQUO]Standard Gluconavii® GDH Blood Glucose Meter[RDQUO] by testing with arterial and neonatal blood samples15
M200 Evaluation of eight commercially available clinical chemistry assays on the ALINITY® C system15
W014 About a case of rhabdomyolysis in a 7 year-old child secondary to a deficiency of very long-chain acyl-coa dehydrogenase (VLCAD)15
T129 Stability of arterial blood gases (ABG)15
T257 Blood coagulation testing and hematological features of thalassemia carriers in pregnant15
Association of lipoprotein(a) with left ventricular hypertrophy in patients with new-onset acute myocardial infarction: A large cross-sectional study15
Editorial board member, Aims and Scope, Publication Info.15
A novel KCNQ2 missense variant in non-syndromic intellectual disability causes mild gain-of-function of Kv7.2 channel15
LIS requirements for laboratory management15
M122 Sample rejection of mixed body fluids for CSF identification – The utility of fluid protein concentration14
Sclerostin in ankylosing spondylitis: A meta-analysis14
W224 Is there a relationship between seminal zinc concentration and sperm quality in overweight men?14
W055 Serum erythroferrone in chronic kidney disease patients14
Emergency severity level-3 patient flow based on point-of-care testing improves patient outcomes14
T201 The liver enzymes in patients with cirrhosis and hepatocellular carcinoma (HCC)14
T017 Analytical and clinical assessment of prostate specific antigen by chemiluminescence HISCL-5000 immunoassay14
Risk stratification and predictive value of serum sodium fluctuation for adverse prognosis in acute coronary syndrome patients14
Expanding the clinical utility of reporter gene assay to infliximab biosimilars14
T079 High sensitive troponin assays in differentiating acute coronary syndrome from healthy individuals14
M052 Evaluation of extracellular fatty acid synthase and copeptin in obesity induced insulin resistance and metabolic syndrome14
W226 NGS-based pipeline for routine non-invasive preimplantation genetic assessment in IVF14
Procalcitonin and transferrin as a survival markers of patients with COVID-1914
Quality management, ethical considerations, and emerging challenges in genomics and biobanking: A comprehensive review14
W157 Prostaglandin-D-synthase levels in cerebrospinal fluid associated with altered tau proteins in patients with suspected Alzheimer’s disease14
T181 Establishment of influence factors and ageing models for thyroid hormones in the elderly using real-world big data14
Analysis of two intestinal bacterial metabolites (trimethylamine N-oxide and phenylacetylglutamine) in human serum samples of patients with T2DM and AMI using a liquid chromatography tandem mass spect14
Application of neutrophil-to-lymphocyte ratio in the diagnosis of complicated pediatric appendicitis13
Analysis of gene mutation characteristics and its correlation with prognosis in patients with myelodysplastic syndromes13
Relationships among maternal monosomy X mosaicism, maternal trisomy, and discordant sex chromosome aneuploidies13
The association of siMS and siMS risk scores with risk factors for cardiovascular events in university students with metabolic syndrome13
Clinical performance evaluation of smartchek SARS-COV-2 detection kit and smartchek SARS-COV-2 fast detection kit for detection of severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) in saliv13
Serologic profile of individuals who contracted COVID-19 despite triple vaccination13
Study of teratozoospermia in our population through analysis of seminal fluid in the assisted human reproduction unit of a Spanish referral hospital13
Evaluation of the performance of biochemical ratios and albumin’s gradient in the etiological exploration of ascitic fluid13
Evaluating the utility of using glycated albumin in diagnosing dysglycemia among Saudis- A pilot study13
Distance changes of lymphocyte quantity and function in patients with COVID-1913
The assessment of endocannabinoids and N-acylethanolamines in human hair: Associations with sociodemographic and psychological variables13
Lean adolescents with insulin resistance display higher angiopoietin like protein 3, ApoC-III and chylomicron remnant dyslipidemia13
Non-invasive fetal RHD genotyping in d- (RH:-1) patients with RHD genomic sequences: retrospective study over 11 years13
Apolipoprotein C-III mucin core 2 O-Linked glycoforms: Hiding in plain sight13
Novel biomarkers to improve diagnosis and monitor prognosis13
Bacteriological profile and antimicrobial susceptibility patterns of organisms responsible for blood stream infections in intensive care unit patients13
The role of laboratory diagnostics in determining the physical health of psychiatric inpatients13
Leveraging machine learning to improve current diagnostic algorithms and laboratory stewardship13
Advantages of the implementation of a second-tier test strategy in the newborn screening13
Cytomegalovirus antigen-specific multi-cytokine immune responses in patients with rheumatic diseases under different cytomegalovirus infection status: A case-control study13
A retrospective analysis of 1600 infertility patients with azoospermia and severe oligozoospermia13
Mild-to-moderate COVID-19 may affect nervous system function in convalescents13
Waste management in clinical laboratories13
Enhancing enteric pathogen detection: implementation and impact of multiplex PCR for improved diagnosis and surveillance13
Utility of serum indices for predicting liver fibrosis13
Liaison MeMed BV: A new approach for a quicker diagnosis between viral and bacterial infections in a cohort of pediatric patients13
Overweight and obesity: The weight of genes13
The association between the PON1 genes rs662 and rs854560 and the metabolic syndrome in patients with obesity12
Brucella outbreak linked to ice cream: A Lebanese case series12
Strategic collaboration to address nitrous oxide challenges: Establishment of an international consortium of experts12
Association of HIV-1 Nef polymorphisms with coronary artery disease in HIV-positive patients12
Targeting tumour markers in ovarian cancer treatment12
Metabolomic profiling of serum and tongue coating of pregnant women with intrahepatic cholestasis in pregnancy12
HDL subfractions determined by microfluidic chip electrophoresis predict the vulnerability of intracranial plaque: A HRMRI study12
Validation of a liquid chromatography coupled to tandem mass spectrometry method for simultaneous quantification of tryptophan and 10 key metabolites of the kynurenine pathway in plasma and urine: App12
Estimation of FGF-23 level in patients with chronic kidney disease with or without vitamin D supplementation12
Performance verification and reference interval establishment of serum/plasma aldosterone by a novel “sandwich” chemiluminescent immunoassay12
Impact of CSF collection volume in the accuracy of Alzheimer’s disease biomarker results12
Comparison of clot waveform analysis with or without adjustment between prothrombin time and activated partial thromboplastin time assays to assess in vitro effects of direct oral anticoagulants12
The role of tubulointerstitial markers in differential diagnosis and prognosis in patients with type 2 diabetes and biopsy proven diabetic kidney disease12
Limitations of hemolysis-based correction for potassium measurement in hemolyzed whole blood samples12
Pediatric reference values of NT-proBNP and Galectin-3 based on a French cohort12
Proteomics of neuropsychiatric disorders12
Corrigendum to “The impact of triadimenol on male fertility: An in vitro study and molecular docking examination” [Reprod. Toxicol. 132 (2025) 108861]12
Challenges with sweat testing – A quality improvement initiative12
Revolutionizing cell-based analyses: An electrochemical analysis platform with integrated incubator capabilities12
MicroRNA biomarkers for predicting treatment response and resistance to bevacizumab in cancer12
Plasma cellular prion protein concentrations correlate with severity and prognosis of aneurysmal subarachnoid hemorrhage12
Association between apolipoprotein B/A1 and the risk of metabolic dysfunction associated fatty liver disease according to different lipid profiles in a Chinese population: A cross-sectional study12
Evaluating the efficacy of a long-read sequencing-based approach in the clinical diagnosis of neonatal congenital adrenocortical hyperplasia12
A novel variant of the POLR3A gene in a patient with hypomyelinating POLR3-related leukodystrophy12
Autologous platelet-rich plasma as adjuvant treatment in patients with refractory endometrial growth: Preliminary results from a 2-year prospective study in a Spanish reference unit of assisted human 11
An adult patient with Tatton-Brown-Rahman Syndrome: case report and novel DNMT3A variant not previously reported11
Indisputable vs. questionable actionable secondary findings in a cohort of 500 Lebanese participants: What to report to the patient?11
M207 Simultaneous measurements of nicotine and its metabolites in urine by LC-MS/MS in the general Korean population11
A rare case of potter’s sequence with sex reversal in a 33 – Year old female”11
Dihydropyrimidine dehydrogenase phenotyping by LC-MS/MS determination of uracil in human plasma11
Assessment of a novel point-of-care system for chemistry panel testing11
IgE sensitization to ragweed and Japanese cedar pollen due to pectate lyase11
Corrigendum to “Tuberculosis-targeted next-generation sequencing and machine learning: An ultrasensitive diagnostic strategy for paucibacillary pulmonary tuberculosis and tuberculous meningitis” [Clin11
Stabilization of glucose concentration in the new vacuette® FC mix blood collection tube for diagnosis of diabetes and gestational diabetes11
Top-down mass spectrometry for in-depth analysis of protein biomarkers: A novel methodology for precision diagnostics11
Evaluating data accuracy in clinical laboratory requests: A therapeutic drug monitoring study11
Deciphering biological impact of nitrous oxide abuse: Insights from targeted metabolomics analysis11
W125 Evaluation of HIV viral load specimen rejections in the pre-analytical phase at centralized testing site in Lusaka province, Zambia11
Pathfast POCT: Evaluation presepsin as a key biomarker in sepsis11
Corrigendum to “Plasma neurofilament light chain (NfL) reference interval determination in an age-stratified cognitively unimpaired cohort” [Clin. Chim. Acta 535 (2022) 153-156]11
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