Circulation Research

(The TQCC of Circulation Research is 80. The table below lists those papers that are above that threshold based on CrossRef citation counts. The publications cover those that have been published in the past four years, i.e., from 2019-03-01 to 2023-03-01.)
Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases3186
Power spectral analysis of heart rate and arterial pressure variabilities as a marker of sympatho-vagal interaction in man and conscious dog.2921
Some statistical methods useful in circulation research.2902
Endothelial Dysfunction in Cardiovascular Diseases: The Role of Oxidant Stress2506
Bone Marrow Origin of Endothelial Progenitor Cells Responsible for Postnatal Vasculogenesis in Physiological and Pathological Neovascularization2329
A Novel Angiotensin-Converting Enzyme–Related Carboxypeptidase (ACE2) Converts Angiotensin I to Angiotensin 1-92050
NAD(P)H Oxidase1989
Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells.1771
Adipose-Derived Stem Cells for Regenerative Medicine1696
Role of endothelium in responses of vascular smooth muscle.1584
Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats.1551
Adipose Tissue, Inflammation, and Cardiovascular Disease1473
Endothelial/Pericyte Interactions1436
Endothelial Progenitor Cells1367
Phenotypic Heterogeneity of the Endothelium1197
Isolation and Expansion of Adult Cardiac Stem Cells From Human and Murine Heart1155
Distinct Roles of Autophagy in the Heart During Ischemia and Reperfusion1139
Load Independence of the Instantaneous Pressure-Volume Ratio of the Canine Left Ventricle and Effects of Epinephrine and Heart Rate on the Ratio1119
A dynamic model of the cardiac ventricular action potential. I. Simulations of ionic currents and concentration changes.1108
Mesenchymal Stem Cells and Their Potential as Cardiac Therapeutics1101
Marrow-Derived Stromal Cells Express Genes Encoding a Broad Spectrum of Arteriogenic Cytokines and Promote In Vitro and In Vivo Arteriogenesis Through Paracrine Mechanisms1069
Fiber Orientation in the Canine Left Ventricle during Diastole and Systole1060
A model of the ventricular cardiac action potential. Depolarization, repolarization, and their interaction.1035
The Circulation of the Fetus in Utero1019
Endothelial Cell Migration During Angiogenesis993
Carotid bifurcation atherosclerosis. Quantitative correlation of plaque localization with flow velocity profiles and wall shear stress.976
Phosphate Regulation of Vascular Smooth Muscle Cell Calcification972
Instantaneous Pressure-Volume Relationships and Their Ratio in the Excised, Supported Canine Left Ventricle971
Reflex Regulation of Arterial Pressure during Sleep in Man970
Antiinflammatory Properties of HDL966
AMP-Activated Protein Kinase in Metabolic Control and Insulin Signaling964
Beta 1- and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor dow964
The [18F]fluorodeoxyglucose method for the measurement of local cerebral glucose utilization in man.928
Acute Vascular Endothelial Changes Associated with Increased Blood Velocity Gradients917
Identification of Epoxyeicosatrienoic Acids as Endothelium-Derived Hyperpolarizing Factors886
Myocardial infarct size and ventricular function in rats.884
Endothelial Extracellular Matrix880
Circus movement in rabbit atrial muscle as a mechanism of tachycardia. III. The "leading circle" concept: a new model of circus movement in cardiac tissue without the involvement of an anatomical obst853
Molecular characterization of angiotensin II--induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts. Critical role of the AT1 receptor subtype.848
Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical.821
Sirt1 Regulates Aging and Resistance to Oxidative Stress in the Heart805
Mechanisms Underlying Endothelial Dysfunction in Diabetes Mellitus794
Effect of Age and High Blood Pressure on Barorefiex Sensitivity in Man778
Phenotypic Heterogeneity of the Endothelium772
Inflammatory Cytokines and Postmyocardial Infarction Remodeling764
Role of Akt Signaling in Vascular Homeostasis and Angiogenesis754
Hypoxia-Induced Pulmonary Vascular Remodeling751
New Insights Into the Regulation of HDL Metabolism and Reverse Cholesterol Transport737
Nonuniform Recovery of Excitability in Ventricular Muscle727
Innate and Adaptive Immunity in the Pathogenesis of Atherosclerosis727
Agonist-induced endothelium-dependent relaxation in rat thoracic aorta may be mediated through cGMP.725
Inflammatory Mediators and the Failing Heart722
Characterization and Enrichment of Cardiomyocytes Derived From Human Embryonic Stem Cells700
Angiotensin II induces hypertrophy, not hyperplasia, of cultured rat aortic smooth muscle cells.700
Hypoxia Regulates Vascular Endothelial Growth Factor Gene Expression in Endothelial Cells699
Biological actions and properties of endothelium-derived nitric oxide formed and released from artery and vein.692
Vascular Calcification690
Measurement of Local Blood Flow with Hydrogen Gas688
Experimental Subendocardial Ischemia in Dogs with Normal Coronary Arteries681
Relating extracellular potentials and their derivatives to anisotropic propagation at a microscopic level in human cardiac muscle. Evidence for electrical uncoupling of side-to-side fiber connections 675
Cardioprotective Effect of Diazoxide and Its Interaction With Mitochondrial ATP-Sensitive K + Channels673
The role of adenosine in the regulation of coronary blood flow.643
Canine myocardial reperfusion injury. Its reduction by the combined administration of superoxide dismutase and catalase.635
Immunity and Inflammation in Atherosclerosis626
Blockade of ATP-sensitive potassium channels prevents myocardial preconditioning in dogs.616
Human Embryonic Stem Cells Develop Into Multiple Types of Cardiac Myocytes609
Flow patterns and spatial distribution of atherosclerotic lesions in human coronary arteries.607
Stress (Heat Shock) Proteins607
Equations for Measuring Blood Flow by External Monitoring of Radioisotopes603
Chronic exercise in dogs increases coronary vascular nitric oxide production and endothelial cell nitric oxide synthase gene expression.600
MicroRNAs Play an Essential Role in the Development of Cardiac Hypertrophy599
The discontinuous nature of propagation in normal canine cardiac muscle. Evidence for recurrent discontinuities of intracellular resistance that affect the membrane currents.599
Regional Myocardial Function during Acute Coronary Artery Occlusion and Its Modification by Pharmacologic Agents in the Dog598
The Intima597
Myocardial Cell Death in Human Diabetes595
NAD(P)H Oxidase 4 Mediates Transforming Growth Factor-β1–Induced Differentiation of Cardiac Fibroblasts Into Myofibroblasts594
Brief Reviews590
Abnormal intracellular calcium handling in myocardium from patients with end-stage heart failure.588
What Is the Role of β-Adrenergic Signaling in Heart Failure?581
Matrix Metalloproteinases and Cardiovascular Disease580
Chemokines in the Pathogenesis of Vascular Disease573
Calcineurin/NFAT Coupling Participates in Pathological, but not Physiological, Cardiac Hypertrophy572
Dilated Cardiomyopathy in Transgenic Mice With Cardiac-Specific Overexpression of Tumor Necrosis Factor-α569
Vascular Trauma Induces Rapid but Transient Mobilization of VEGFR2 + AC133 + Endothelial Precursor Cells569
Angiotensin II Stimulation of NAD(P)H Oxidase Activity553
Ischemic preconditioning slows energy metabolism and delays ultrastructural damage during a sustained ischemic episode.551
Control of Heart Rate by the Autonomic Nervous System551
Total and Regional Coronary Blood Flow Measured by Radioactive Microspheres in Conscious and Anesthetized Dogs551
Overview of PDEs and Their Regulation550
Intravenous Transfusion of Endothelial Progenitor Cells Reduces Neointima Formation After Vascular Injury550
Ca 2+ /Calmodulin–Dependent Protein Kinase Modulates Cardiac Ryanodine Receptor Phosphorylation and Sarcoplasmic Reticulum Ca 2+ L550
Sedentary Behavior, Exercise, and Cardiovascular Health550
Oxidative Stress as a Regulator of Gene Expression in the Vasculature548
Apoptosis in Ischemic and Reperfused Rat Myocardium543
Dicer Dependent MicroRNAs Regulate Gene Expression and Functions in Human Endothelial Cells543
Activation of Receptor for Advanced Glycation End Products543
Influence of chronic captopril therapy on the infarcted left ventricle of the rat.542
Oxidant Signaling in Vascular Cell Growth, Death, and Survival542
Differentiation of Pluripotent Embryonic Stem Cells Into Cardiomyocytes541
Role of intracellular Na+ in Ca2+ overload and depressed recovery of ventricular function of reperfused ischemic rat hearts. Possible involvement of H+-Na+ and Na+-Ca2+ exchange.540
Balloon angioplasty. Natural history of the pathophysiological response to injury in a pig model.536
Matrix Metalloproteinases535
Mitochondrial Dysfunction in Atherosclerosis528
Mechanical Properties of Arteries in Vivo526
A Lamellar Unit of Aortic Medial Structure and Function in Mammals524
Cardioprotective Actions by a Water-Soluble Carbon Monoxide–Releasing Molecule524
Intravenous Administration of Human Bone Marrow Stromal Cells Induces Angiogenesis in the Ischemic Boundary Zone After Stroke in Rats524
Alterations with Age in the Viscoelastic Properties of Human Arterial Walls520
Microneurographic studies of the mechanisms of sympathetic nerve responses to static exercise in humans.517
Tumor necrosis factor downregulates an endothelial nitric oxide synthase mRNA by shortening its half-life.517
Effects of Angiotensin II Infusion on the Expression and Function of NAD(P)H Oxidase and Components of Nitric Oxide/cGMP Signaling511
Molecular Regulation of Atrioventricular Valvuloseptal Morphogenesis506
Cardiomyopathy of the aging human heart. Myocyte loss and reactive cellular hypertrophy.506
Adhesion Mechanisms in Platelet Function500
Protective Role of Interleukin-10 in Atherosclerosis500
The Antianginal Drug Trimetazidine Shifts Cardiac Energy Metabolism From Fatty Acid Oxidation to Glucose Oxidation by Inhibiting Mitochondrial Long-Chain 3-Ketoacyl Coenzyme A Thiolase500
Replication of smooth muscle cells in vascular disease.498
Flow of "injury" current and patterns of excitation during early ventricular arrhythmias in acute regional myocardial ischemia in isolated porcine and canine hearts. Evidence for two different arrhyth498
Bone Marrow Stem Cells Prevent Left Ventricular Remodeling of Ischemic Heart Through Paracrine Signaling497
Blood pressure and heart rate variabilities in normotensive and hypertensive human beings.497
The Late Phase of Preconditioning496
Postconditioning: A Form of “Modified Reperfusion” Protects the Myocardium by Activating the Phosphatidylinositol 3-Kinase-Akt Pathway496
Control of coronary vascular tone by nitric oxide.495
CCL2/Monocyte Chemoattractant Protein-1 Regulates Inflammatory Responses Critical to Healing Myocardial Infarcts495
Dobutamine: development of a new catecholamine to selectively increase cardiac contractility.494
Heterogeneity within the ventricular wall. Electrophysiology and pharmacology of epicardial, endocardial, and M cells.493
Heart Valve Development492
Platelets as Immune Cells491
Selective Suppression of Endothelial Cell Apoptosis by the High Molecular Weight Form of Adiponectin490
Early afterdepolarizations: mechanism of induction and block. A role for L-type Ca2+ current.486
Apoptosis Regulates Human Vascular Calcification In Vitro483
Leptin, the Product of Ob Gene, Promotes Angiogenesis482
A Novel Form of Short QT Syndrome (SQT3) Is Caused by a Mutation in the KCNJ2 Gene482
Mitochondrial DNA Damage and Dysfunction Associated With Oxidative Stress in Failing Hearts After Myocardial Infarction480
Relation between myocardial function and expression of sarcoplasmic reticulum Ca(2+)-ATPase in failing and nonfailing human myocardium.480
The Transient Receptor Potential Protein Homologue TRP6 Is the Essential Component of Vascular α 1 -Adrenoceptor–Activated Ca 2+ -480
Spontaneous Cardiomyocyte Differentiation From Adipose Tissue Stroma Cells475
Tie2 Receptor Ligands, Angiopoietin-1 and Angiopoietin-2, Modulate VEGF-Induced Postnatal Neovascularization475
Vagal stimulation and prevention of sudden death in conscious dogs with a healed myocardial infarction.475
Alterations of K+ currents in isolated human ventricular myocytes from patients with terminal heart failure.474
Mechanical Signaling and the Cellular Response to Extracellular Matrix in Angiogenesis and Cardiovascular Physiology472
Effects of fibrous cap thickness on peak circumferential stress in model atherosclerotic vessels.471
Ca 2+ /Calmodulin-Dependent Protein Kinase II Phosphorylation Regulates the Cardiac Ryanodine Receptor470
Mitochondrial Electron Transport Complex I Is a Potential Source of Oxygen Free Radicals in the Failing Myocardium468
Expression of a Functionally Active gp91phox-Containing Neutrophil-Type NAD(P)H Oxidase in Smooth Muscle Cells From Human Resistance Arteries466
Targeted ablation of the phospholamban gene is associated with markedly enhanced myocardial contractility and loss of beta-agonist stimulation.465
Ionic Remodeling Underlying Action Potential Changes in a Canine Model of Atrial Fibrillation458
Angiotensin II induces smooth muscle cell proliferation in the normal and injured rat arterial wall.458
Is the Failing Heart Energy Starved?457
Bone Marrow-Derived Cells Do Not Incorporate Into the Adult Growing Vasculature456
The Transforming Growth Factor-β Superfamily Member Growth-Differentiation Factor-15 Protects the Heart From Ischemia/Reperfusion Injury456
Role of the Baroreceptor Reflex in Daily Control of Arterial Blood Pressure and Other Variables in Dogs455
Ionic Mechanisms of Propagation in Cardiac Tissue455
The functional role of structural complexities in the propagation of depolarization in the atrium of the dog. Cardiac conduction disturbances due to discontinuities of effective axial resistivity.454
Endothelial and Antithrombotic Actions of HDL453
Cell Type–Specific Regulation of Angiogenic Growth Factor Gene Expression and Induction of Angiogenesis in Nonischemic Tissue by a Constitutively Active Form of Hypoxia-Inducible Factor 1453
Activation of Platelet Function Through G Protein–Coupled Receptors450
Apelin, the Novel Endogenous Ligand of the Orphan Receptor APJ, Regulates Cardiac Contractility450
Circus Movement in Rabbit Atrial Muscle as a Mechanism of Tachycardia449
Opening of Mitochondrial K ATP Channels Triggers the Preconditioned State by Generating Free Radicals449
Tissue Engineering of Vascularized Cardiac Muscle From Human Embryonic Stem Cells448
Deoxymyoglobin Is a Nitrite Reductase That Generates Nitric Oxide and Regulates Mitochondrial Respiration448
Regulation of large cerebral arteries and cerebral microvascular pressure.447
Remodeling of the rat right and left ventricles in experimental hypertension.447
The δ C Isoform of CaMKII Is Activated in Cardiac Hypertrophy and Induces Dilated Cardiomyopathy and Heart Failure446
Identification of Distinct Luminal Domains for Macromolecules, Erythrocytes, and Leukocytes Within Mammalian Capillaries444
Oxidative Stress-Induced Actin Reorganization Mediated by the p38 Mitogen-Activated Protein Kinase/Heat Shock Protein 27 Pathway in Vascular Endothelial Cells444
Vascular Smooth Muscle Cells Undergo Telomere-Based Senescence in Human Atherosclerosis444
Role of the Mitochondrial Permeability Transition in Myocardial Disease443
Cardiac Stem Cell and Myocyte Aging, Heart Failure, and Insulin-Like Growth Factor-1 Overexpression443
Heterogeneous behavior of the canine arterial and venous wall. Importance of the endothelium.441
Indicator Transit Time Considered as a Gamma Variate441
Angiopoietin-1 Regulates Endothelial Cell Survival Through the Phosphatidylinositol 3′-Kinase/Akt Signal Transduction Pathway441
Cloning and Characterization of α1H From Human Heart, a Member of the T-Type Ca 2+ Channel Gene Family439
The Giant Protein Titin438
Conduction Slowing and Sudden Arrhythmic Death in Mice With Cardiac-Restricted Inactivation of Connexin43437
Diabetic Cardiomyopathy434
Myocytes Die by Multiple Mechanisms in Failing Human Hearts433
Direct detection of free radicals in the reperfused rat heart using electron spin resonance spectroscopy.432
Effect of hypercholesterolemia on vascular reactivity in the rabbit. I. Endothelium-dependent and endothelium-independent contractions and relaxations in isolated arteries of control and hypercholeste432
Nitric Oxide and Cardiac Function431
Significance of quiescent smooth muscle migration in the injured rat carotid artery.431
Heparan Sulfate Proteoglycan Is a Mechanosensor on Endothelial Cells431
Structural Basis for the Static Mechanical Properties of the Aortic Media430
Resistance to blood flow in microvessels in vivo.429
Release of Adenosine from Ischemic Brain428
Influences of anisotropic tissue structure on reentrant circuits in the epicardial border zone of subacute canine infarcts.425
Aging-Induced Phenotypic Changes and Oxidative Stress Impair Coronary Arteriolar Function425
Lipid-membrane interactions and the pathogenesis of ischemic damage in the myocardium.424
Nitric Oxide and Cardiac Function423
Regulation of Cardiac L-Type Calcium Channels by Protein Kinase A and Protein Kinase C423
Role of glycolytic products in damage to ischemic myocardium. Dissociation of adenosine triphosphate levels and recovery of function of reperfused ischemic hearts.422
Role of Integrins in Endothelial Mechanosensing of Shear Stress421
The Mitochondrial Death Pathway and Cardiac Myocyte Apoptosis421
Cardiac Stem Cells Possess Growth Factor-Receptor Systems That After Activation Regenerate the Infarcted Myocardium, Improving Ventricular Function and Long-Term Survival421
Active oxygen species stimulate vascular smooth muscle cell growth and proto-oncogene expression.418
CD31 but Not CD31 + Cardiac Side Population Cells Exhibit Functional Cardiomyogenic Differentiation417
What Causes Sudden Death in Heart Failure?416
A Single Na + Channel Mutation Causing Both Long-QT and Brugada Syndromes416
Heme Oxygenase-1 Regulates Cardiac Mitochondrial Biogenesis via Nrf2-Mediated Transcriptional Control of Nuclear Respiratory Factor-1413
Characteristics of the Delayed Rectifier Current (I Kr and I Ks ) in Canine Ventricular Epicardial, Midmyocardial, and Endocardial412
Regulation of NADPH Oxidases410
Patterns of Vascular Cell Adhesion Molecule-1 and Intercellular Adhesion Molecule-1 Expression in Rabbit and Mouse Atherosclerotic Lesions and at Sites Predisposed to Lesion Formation409
Direct Evidence of Endothelial Oxidative Stress With Aging in Humans409
Mechanical stress mechanisms and the cell. An endothelial paradigm.408
Blood flow in microvascular networks. Experiments and simulation.408
Spiral waves of excitation underlie reentrant activity in isolated cardiac muscle.408
Functional Distribution of Right and Left Stellate Innervation to the Ventricles408
Cytokine-stimulated human vascular smooth muscle cells synthesize a complement of enzymes required for extracellular matrix digestion.408
Vascular Cell Senescence407
Calcium Fluxes Involved in Control of Cardiac Myocyte Contraction407
Oscillatory and Steady Laminar Shear Stress Differentially Affect Human Endothelial Redox State406
Voltage-dependent block of calcium channel current in the calf cardiac Purkinje fiber by dihydropyridine calcium channel antagonists.405
A gp91phox Containing NADPH Oxidase Selectively Expressed in Endothelial Cells Is a Major Source of Oxygen Radical Generation in the Arterial Wall404
Membrane Estrogen Receptor Engagement Activates Endothelial Nitric Oxide Synthase via the PI3-Kinase–Akt Pathway in Human Endothelial Cells403
Rho Kinases in Cardiovascular Physiology and Pathophysiology402
Superoxide Production in Vascular Smooth Muscle Contributes to Oxidative Stress and Impaired Relaxation in Atherosclerosis402
Peroxisome Proliferator-Activated Receptors and Atherogenesis397
Coupling of Cardiac Electrical Activity Over Extended Distances by Fibroblasts of Cardiac Origin397
Increased Vulnerability to Atrial Fibrillation in Transgenic Mice With Selective Atrial Fibrosis Caused by Overexpression of TGF-β1397
Rapamycin-FKBP Inhibits Cell Cycle Regulators of Proliferation in Vascular Smooth Muscle Cells395
NG-nitro L-arginine methyl ester and other alkyl esters of arginine are muscarinic receptor antagonists.395
Epicardium-Derived Cells Contribute a Novel Population to the Myocardial Wall and the Atrioventricular Cushions394
Elevated Placental Soluble Vascular Endothelial Growth Factor Receptor-1 Inhibits Angiogenesis in Preeclampsia393
Length of excitation wave and susceptibility to reentrant atrial arrhythmias in normal conscious dogs.393
Mathematical Model of an Adult Human Atrial Cell393
Neurogenic Hypertension in the Rat392
TRPV2 Is a Component of Osmotically Sensitive Cation Channels in Murine Aortic Myocytes392
Marked reduction of free radical generation and contractile dysfunction by antioxidant therapy begun at the time of reperfusion. Evidence that myocardial "stunning" is a manifestation of reperfusion i392
Effect of Elevated Left Atrial Pressure and Decreased Plasma Protein Concentration on the Development of Pulmonary Edema389
Rate of Calcium Binding and Uptake in Normal Animal and Failing Human Cardiac Muscle: MEMBRANE VESICLES (RELAXING SYSTEM) AND MITOCHONDRIA388
Contractile State of Cardiac Muscle Obtained from Cats with Experimentally Produced Ventricular Hypertrophy and Heart Failure388
Small-Diameter Artificial Arteries Engineered In Vitro386
Gene Expression in Fibroblasts and Fibrosis385
Cyclic GMP Phosphodiesterases and Regulation of Smooth Muscle Function385
Left Ventricular Tension and Stress in Man384
Delayed effects of sublethal ischemia on the acquisition of tolerance to ischemia.384
Vascular Endothelial Growth Factor 165 Gene Transfer Augments Circulating Endothelial Progenitor Cells in Human Subjects384
Regulation of Nitric Oxide-Sensitive Guanylyl Cyclase383
Theoretical Basis of Indicator-Dilution Methods For Measuring Flow and Volume383
Circus movement in rabbit atrial muscle as a mechanism of tachycardia. II. The role of nonuniform recovery of excitability in the occurrence of unidirectional block, as studied with multiple microelec382
Survey of Studies Examining Mammalian Cardiomyocyte DNA Synthesis381
Glycation, Inflammation, and RAGE380
Bone Marrow Cells Differentiate in Cardiac Cell Lineages After Infarction Independently of Cell Fusion380
Neural Crest and Cardiovascular Patterning379
Epigenetic Modification of the Renin-Angiotensin System in the Fetal Programming of Hypertension379
Sustained depolarization-induced outward current in human atrial myocytes. Evidence for a novel delayed rectifier K+ current similar to Kv1.5 cloned channel currents.378
Ionic Mechanisms Responsible for the Electrocardiographic Phenotype of the Brugada Syndrome Are Temperature Dependent377
The ventricular pressure-volume diagram revisited.376
Peroxisome Proliferator-Activated Receptor Gamma Activators Inhibit Gene Expression and Migration in Human Vascular Smooth Muscle Cells375
Physiologic Evidence for a Dual A-V Transmission System373
Volume loading slows left ventricular isovolumic relaxation rate. Evidence of load-dependent relaxation in the intact dog heart.372
Gene expression of the cardiac Na(+)-Ca2+ exchanger in end-stage human heart failure.372
Hypoxia induces apoptosis with enhanced expression of Fas antigen messenger RNA in cultured neonatal rat cardiomyocytes.371
Endothelial Cells of Hematopoietic Origin Make a Significant Contribution to Adult Blood Vessel Formation371
Ionic Mechanism of Action Potential Prolongation in Ventricular Myocytes From Dogs With Pacing-Induced Heart Failure371
Angiotensin II-forming pathways in normal and failing human hearts.369
Protein Kinase Cε Interacts With and Inhibits the Permeability Transition Pore in Cardiac Mitochondria369
Lipoprotein Uptake and Metabolism by Rat Aortic Smooth Muscle Cells in Tissue Culture368
Ischemic preconditioning reduces infarct size in swine myocardium.367
Stimulation of hypertrophy of cultured neonatal rat heart cells through an alpha 1-adrenergic receptor and induction of beating through an alpha 1- and beta 1-adrenergic receptor interaction. Evidence367
Novel Role of gp91 phox -Containing NAD(P)H Oxidase in Vascular Endothelial Growth Factor–Induced Signaling and Angiogenesis367
A Theoretical Analysis of Intracavitary Blood Mass Influence on the Heart-Lead Relationship366
Nitric Oxide Synthesis by Cultured Endothelial Cells Is Modulated by Flow Conditions366
What Mechanisms Underlie Diastolic Dysfunction in Heart Failure?365
Stimulation of the Stress-Activated Mitogen-Activated Protein Kinase Subfamilies in Perfused Heart365
Circulatory Changes during Growth in the Fetal Lamb364
Sympathetic nerve activity: role in regulation of blood pressure in the spontaenously hypertensive rat.364
The plasma membrane sodium-hydrogen exchanger and its role in physiological and pathophysiological processes.363
Myocyte Death, Growth, and Regeneration in Cardiac Hypertrophy and Failure363
Transgenic CaMKIIδ C Overexpression Uniquely Alters Cardiac Myocyte Ca 2+ Handling362
Rho GTPases, Statins, and Nitric Oxide361
The Dystrophin Glycoprotein Complex361
Myosin Heavy Chain Isoform Expression in the Failing and Nonfailing Human Heart361
Dichloroacetate Prevents and Reverses Pulmonary Hypertension by Inducing Pulmonary Artery Smooth Muscle Cell Apoptosis361
Direct evidence that the greater contractility of resistance vessels in spontaneously hypertensive rats is associated with a narrowed lumen, a thickened media, and an increased number of smooth muscle361
Morphological, biochemical, and electrophysiological characterization of a clonal cell (H9c2) line from rat heart.360
Hemoglobin Scavenger Receptor CD163 Mediates Interleukin-10 Release and Heme Oxygenase-1 Synthesis360
Longitudinal Gradients in Periarteriolar Oxygen Tension359
Rescue of Monocrotaline-Induced Pulmonary Arterial Hypertension Using Bone Marrow–Derived Endothelial-Like Progenitor Cells357
Experimental and Clinical Regenerative Capability of Human Bone Marrow Cells After Myocardial Infarction357
Cardiomyocyte Cell Cycle Regulation356
TRPV4 Forms a Novel Ca 2+ Signaling Complex With Ryanodine Receptors and BK Ca Channels356
Soluble Epoxide Hydrolase Regulates Hydrolysis of Vasoactive Epoxyeicosatrienoic Acids355
The Endothelial Glycocalyx Protects Against Myocardial Edema354
Excitation-Contraction Coupling in Rabbit Aorta Studied by the Lanthanum Method for Measuring Cellular Calcium Influx354
Hypertension Caused by Angiotensin II Infusion Involves Increased Superoxide Production in the Central Nervous System354
Angiopoietin-1 Is an Antipermeability and Anti-Inflammatory Agent In Vitro and Targets Cell Junctions353
Dephosphorylation and Intracellular Redistribution of Ventricular Connexin43 During Electrical Uncoupling Induced by Ischemia353
p22phox mRNA Expression and NADPH Oxidase Activity Are Increased in Aortas From Hypertensive Rats352
Elevation in cytosolic free calcium concentration early in myocardial ischemia in perfused rat heart.351
PGH synthase and lipoxygenase generate superoxide in the presence of NADH or NADPH.351
Cellular Basis of Abnormal Calcium Transients of Failing Human Ventricular Myocytes351
Nuclear Receptor Signaling and Cardiac Energetics350
Collagen remodeling of the pressure-overloaded, hypertrophied nonhuman primate myocardium.350
Atrial stretch, not pressure, is the principal determinant controlling the acute release of atrial natriuretic factor.350
Myocardial contractile function during ischemia and hypoxia.349
Baroceptor Function in Chronic Renal Hypertension349
Atrial L-Type Ca 2+ Currents and Human Atrial Fibrillation349
Diverse Origin and Function of Cells With Endothelial Phenotype Obtained From Adult Human Blood348
Heart Failure With Preserved Ejection Fraction In Perspective348
Resistivity of Body Tissues at Low Frequencies347
Pathophysiology of Vascular Calcification in Chronic Kidney Disease347
Smooth muscle cell migration and matrix metalloproteinase expression after arterial injury in the rat.347
Peroxisome Proliferator-Activated Receptor Activators Inhibit Thrombin-Induced Endothelin-1 Production in Human Vascular Endothelial Cells by Inhibiting the Activator Protein-1 Signaling Pathway347
Distribution and regulation of blood flow in the fetal and neonatal lamb.346
Detection of Vascular Adhesion Molecule-1 Expression Using a Novel Multimodal Nanoparticle346
Outward K + Current Densities and Kv1.5 Expression Are Reduced in Chronic Human Atrial Fibrillation345
Role of Bradykinin in Protection of Ischemic Preconditioning in Rabbit Hearts344
Measurement of Pulmonary Edema343
Diminished basal nitric oxide release after myocardial ischemia and reperfusion promotes neutrophil adherence to coronary endothelium.343
LDL Cholesterol Upregulates Synthesis of Asymmetrical Dimethylarginine in Human Endothelial Cells343
Mechanisms of Altered Excitation-Contraction Coupling in Canine Tachycardia-Induced Heart Failure, II342
Oscillatory Shear Stress Stimulates Adhesion Molecule Expression in Cultured Human Endothelium342
Similarities of genetic (spontaneous) hypertension. Man and rat.341
Myosin isoenzyme changes in several models of rat cardiac hypertrophy.341
Endothelin-1 induces hypertrophy with enhanced expression of muscle-specific genes in cultured neonatal rat cardiomyocytes.341
Rate-dependent prolongation of cardiac action potentials by a methanesulfonanilide class III antiarrhythmic agent. Specific block of rapidly activating delayed rectifier K+ current by dofetilide.340
Long-Term Inhibition of Rho-Kinase Suppresses Angiotensin II–Induced Cardiovascular Hypertrophy in Rats In Vivo340
Role of the Sodium-Dependent Phosphate Cotransporter, Pit-1, in Vascular Smooth Muscle Cell Calcification339
From Pulsus to Pulseless338
Cardiac-Specific Deletion of Gata4 Reveals Its Requirement for Hypertrophy, Compensation, and Myocyte Viability338
Evidence for Mitochondrial K + Channels and Their Role in Cardioprotection337
Decrease in Mitochondrial Complex I Activity in Ischemic/Reperfused Rat Heart337
Transgenic Expression of Fatty Acid Transport Protein 1 in the Heart Causes Lipotoxic Cardiomyopathy337
Regulation of stroke volume during submaximal and maximal upright exercise in normal man.336
Control of Cardiac Growth by Histone Acetylation/Deacetylation335
Amphipathic metabolites and membrane dysfunction in ischemic myocardium.335
Interleukin-1β and Tumor Necrosis Factor-α Decrease Collagen Synthesis and Increase Matrix Metalloproteinase Activity in Cardiac Fibroblasts In Vitro335
Role of Nrf2 in the Regulation of CD36 and Stress Protein Expression in Murine Macrophages335
Compressibility of the Arterial Wall334
Mechanisms of Vascular Smooth Muscle Cell Migration333
Modulation of Antioxidant Enzyme Expression and Function by Estrogen333
17β-Estradiol Regulation of Human Endothelial Cell Basal Nitric Oxide Release, Independent of Cytosolic Ca 2+ Mobilization332
GDF15/MIC-1 Functions As a Protective and Antihypertrophic Factor Released From the Myocardium in Association With SMAD Protein Activation331
Characterization and Localization of Ventricular Arrhythmias Resulting from Myocardial Ischemia and Infarction330
Regional Cerebral low in Man Determined by Intral-artrial Injection of Radioactive Inert Gas330
Explaining the Phenomenon of Nitrate Tolerance327
Comparison of Simultaneously Recorded Central and Peripheral Arterial Pressure Pulses During Rest, Exercise and Tilted Position in Man326
Ischemic Preconditioning Induces Selective Translocation of Protein Kinase C Isoforms ε and η in the Heart of Conscious Rabbits Without Subcellular Redistribution of Total Protein Kinase C Activity326
Redox-Dependent Transcriptional Regulation325
Apoptosis and Heart Failure325
Heat-shock response is associated with enhanced postischemic ventricular recovery.325
Myocardial Protection at a Crossroads325
Cardiac Hypertrophy in Spontaneously Hypertensive Rats324
The Mediterranean Diet and Cardiovascular Health324
Sarcolemmal Versus Mitochondrial ATP-Sensitive K + Channels and Myocardial Preconditioning323
A subpopulation of cells with unique electrophysiological properties in the deep subepicardium of the canine ventricle. The M cell.323
Mitochondrial PKCε and MAPK Form Signaling Modules in the Murine Heart323
Action potentials, afterpotentials, and arrhythmias.322
Hypoxia on the pulmonary circulation. How and where it acts.322
Regulation of Vascular Calcification by Osteoclast Regulatory Factors RANKL and Osteoprotegerin322
Signaling and Functions of Angiopoietin-1 in Vascular Protection322
Influence of cardiac fiber orientation on wavefront voltage, conduction velocity, and tissue resistivity in the dog.322
Fibrillar collagen and myocardial stiffness in the intact hypertrophied rat left ventricle.322
1α,25-Dihydroxyvitamin D 3 Inhibits Angiogenesis In Vitro and In Vivo322
Superoxide Mediates the Actions of Angiotensin II in the Central Nervous System322
Mechanism and time course of S-T and T-Q segment changes during acute regional myocardial ischemia in the pig heart determined by extracellular and intracellular recordings.322
Contrasting Roles of NADPH Oxidase Isoforms in Pressure-Overload Versus Angiotensin II–Induced Cardiac Hypertrophy322
Evidence for Two Components of Delayed Rectifier K + Current in Human Ventricular Myocytes321
Evidence for Cardiomyocyte Repopulation by Extracardiac Progenitors in Transplanted Human Hearts320
Extracellular Matrix Remodeling and Organization in Developing and Diseased Aortic Valves320
Angiotensin I converting enzyme.318
A dynamic model of the cardiac ventricular action potential. II. Afterdepolarizations, triggered activity, and potentiation.318
Optimal arterial resistance for the maximal stroke work studied in isolated canine left ventricle.318
Peroxynitrite Is a Major Contributor to Cytokine-Induced Myocardial Contractile Failure317
“Stress-Responsive” Mitogen-Activated Protein Kinases (c-Jun N-Terminal Kinases and p38 Mitogen-Activated Protein Kinases) in the Myocardium317
Role for Hydrogen Peroxide in Flow-Induced Dilation of Human Coronary Arterioles317
Mechanisms of Altered Excitation-Contraction Coupling in Canine Tachycardia-Induced Heart Failure, I317
The three-dimensional dynamic geometry of the left ventricle in the conscious dog.317
Atherosclerosis impairs endothelium-dependent vascular relaxation to acetylcholine and thrombin in primates.315
Peroxisome Proliferator-Activated Receptor (PPAR) α and PPARβ/δ, but not PPARγ, Modulate the Expression of Genes Involved in Cardiac Lipid Metabolism315
Differential Distribution of Cardiac Ion Channel Expression as a Basis for Regional Specialization in Electrical Function314
VEGF-D Is the Strongest Angiogenic and Lymphangiogenic Effector Among VEGFs Delivered Into Skeletal Muscle via Adenoviruses314
Clinical Applications of Stem Cells for the Heart313
Role of basic fibroblast growth factor in vascular lesion formation.313
The role of oxygen-derived free radicals in ischemia-induced increases in canine skeletal muscle vascular permeability.313
Long-Term Treatment With a Rho-Kinase Inhibitor Improves Monocrotaline-Induced Fatal Pulmonary Hypertension in Rats313
ATP-regulated K+ channels protect the myocardium against ischemia/reperfusion damage.312
A Cellular Mechanism for the Generation of Ventricular Arrhythmias by Acetylstrophanthidin312
Mature Vascular Endothelium Can Give Rise to Smooth Muscle Cells via Endothelial-Mesenchymal Transdifferentiation312
Simulation Study of Cellular Electric Properties in Heart Failure311
Determination of Regional Cerebral Blood Flow by Inhalation of 133-Xenon311
Differentiation of rat myocytes in single cell cultures with and without proliferating nonmyocardial cells. Cross-striations, ultrastructure, and chronotropic response to isoproterenol.311
Nitric Oxide as a Bifunctional Regulator of Apoptosis310
Pathophysiological Role of Angiotensin II Type 2 Receptor in Cardiovascular and Renal Diseases309
Activation of RhoA by Thrombin in Endothelial Hyperpermeability309
Native Low-Density Lipoprotein Increases Endothelial Cell Nitric Oxide Synthase Generation of Superoxide Anion309
A Breaker of Advanced Glycation End Products Attenuates Diabetes-Induced Myocardial Structural Changes309
Ligand-Independent Activation of Vascular Endothelial Growth Factor Receptor 2 by Fluid Shear Stress Regulates Activation of Endothelial Nitric Oxide Synthase308
Calcification of Vascular Smooth Muscle Cell Cultures307
Phosphorylation of Endothelial Nitric Oxide Synthase in Response to Fluid Shear Stress307
Cell-Demanded Liberation of VEGF 121 From Fibrin Implants Induces Local and Controlled Blood Vessel Growth307
Environmental Cardiology306
Functional Sympatholysis During Muscular Activity306
Valvular Myofibroblast Activation by Transforming Growth Factor-β306
Factors which affect the diastolic pressure-volume curve.305
Electrotonic Modulation of Cardiac Impulse Conduction by Myofibroblasts305
Identification of 5-Lipoxygenase as a Major Gene Contributing to Atherosclerosis Susceptibility in Mice305
Targeted Disruption of the Matrix Metalloproteinase-9 Gene Impairs Smooth Muscle Cell Migration and Geometrical Arterial Remodeling305
George E. Brown memorial lecture. Oxygen radicals in cerebral vascular injury.304
Protein Glycation304
Control of Coronary Blood Flow by an Autoregulatory Mechanism304
Rapid Turnover of Connexin43 in the Adult Rat Heart304
HMG-CoA Reductase Inhibitors Reduce Senescence and Increase Proliferation of Endothelial Progenitor Cells via Regulation of Cell Cycle Regulatory Genes304
Statin Toxicity304
Determinants of left ventricular filling and of the diastolic pressure-volume relation.303
Modulation of ischemia/reperfusion-induced microvascular dysfunction by nitric oxide.303
Myocyte hypertrophy in neonatal rat heart cultures and its regulation by serum and by catecholamines.303
Critical Role for Transient Receptor Potential Channel TRPM4 in Myogenic Constriction of Cerebral Arteries303
Vascular Endothelial Growth Factor Upregulates the Expression of Matrix Metalloproteinases in Vascular Smooth Muscle Cells303
Cardiomyocytes differentiated in vitro from embryonic stem cells developmentally express cardiac-specific genes and ionic currents.303
Interleukin-6 Induces Oxidative Stress and Endothelial Dysfunction by Overexpression of the Angiotensin II Type 1 Receptor303
Mechanical Stretch Enhances mRNA Expression and Proenzyme Release of Matrix Metalloproteinase-2 (MMP-2) via NAD(P)H Oxidase–Derived Reactive Oxygen Species303
Heart Failure in Type 2 Diabetes Mellitus303
Absence of Calsequestrin 2 Causes Severe Forms of Catecholaminergic Polymorphic Ventricular Tachycardia302
Cardiac-Specific Induction of the Transcriptional Coactivator Peroxisome Proliferator-Activated Receptor γ Coactivator-1α Promotes Mitochondrial Biogenesis and Reversible Cardiomyopathy in a Developme302
Signal Transducer and Activator of Transcription 3 Is Required for Myocardial Capillary Growth, Control of Interstitial Matrix Deposition, and Heart Protection From Ischemic Injury302
Role of Krüppel-Like Transcription Factors in Endothelial Biology301
Effect of Ischemia and Antianginal Drugs on the Distribution of Radioactive Microspheres in the Canine Left Ventricle301
SM22α, a Marker of Adult Smooth Muscle, Is Expressed in Multiple Myogenic Lineages During Embryogenesis301
Tie2 Expression and Phosphorylation in Angiogenic and Quiescent Adult Tissues301
Fluorescence Resonance Energy Transfer–Based Analysis of cAMP Dynamics in Live Neonatal Rat Cardiac Myocytes Reveals Distinct Functions of Compartmentalized Phosphodiesterases301
Correlation between acute reductions in myocardial blood flow and function in conscious dogs.300
Ionic bases for electrophysiological distinctions among epicardial, midmyocardial, and endocardial myocytes from the free wall of the canine left ventricle.300
Impairment of Store-Operated Ca 2+ Entry in TRPC4 −/− Mice Interferes With Increase in Lung Microvascular Permeability300
Activation of Transient Receptor Potential Vanilloid Type-1 Channel Prevents Adipogenesis and Obesity300
Adrenergic Effects on Ventricular Vulnerability299
Fluid Shear Stress Stimulates Phosphorylation of Akt in Human Endothelial Cells299
Differential Activation of Mitogen-Activated Protein Kinases by H 2 O 2 and O 2 298
Evidence of the Atrial Location of Receptors Influencing Urine Flow297
α 1 -Adrenergic Receptor Subtypes297
TrpC1 Is a Membrane-Spanning Subunit of Store-Operated Ca 2+ Channels in Native Vascular Smooth Muscle Cells297
Vascular Endothelial Growth Factor–Stimulated Actin Reorganization and Migration of Endothelial Cells Is Regulated via the Serine/Threonine Kinase Akt297
Senescence and Death of Primitive Cells and Myocytes Lead to Premature Cardiac Aging and Heart Failure297
Electrophysiological study of cardiovascular neurons in the rostral ventrolateral medulla in rats.296
Tissue-specific activation of cardiac angiotensin converting enzyme in experimental heart failure.296
Transient Receptor Potential Channels in Cardiovascular Function and Disease296
Compartmentation of Cyclic Nucleotide Signaling in the Heart296
Circulating catecholamine levels in human and experimental hypertension.295
Thioredoxin Promotes ASK1 Ubiquitination and Degradation to Inhibit ASK1-Mediated Apoptosis in a Redox Activity-Independent Manner295
Tissue Resident CCR2− and CCR2+ Cardiac Macrophages Differentially Orchestrate Monocyte Recruitment and Fate Specification Following Myocardial Injury295
Nerve Sprouting and Sudden Cardiac Death294
Role of the Kv4.3 K + Channel in Ventricular Muscle294
Recombinant Adeno-Associated Virus Serotype 9 Leads to Preferential Cardiac Transduction In Vivo294
Endothelial Cell Apoptosis in Angiogenesis and Vessel Regression293
Demonstration of a Dual A-V Nodal Conduction System in the Isolated Rabbit Heart293
Stim1 and Orai1 Mediate CRAC Currents and Store-Operated Calcium Entry Important for Endothelial Cell Proliferation293
Alterations in sarcoplasmic reticulum gene expression in human heart failure. A possible mechanism for alterations in systolic and diastolic properties of the failing myocardium.293
Chronic Hypoxia–Induced Upregulation of Store-Operated and Receptor-Operated Ca 2+ Channels in Pulmonary Arterial Smooth Muscle Cells293
Optical Imaging of the Heart292
Involvement of Extracellular Signal-Regulated Kinases 1/2 in Cardiac Hypertrophy and Cell Death292
Differential Expression of Cardiac Titin Isoforms and Modulation of Cellular Stiffness292
Elevated Cytosolic Na + Decreases Mitochondrial Ca 2+ Uptake During Excitation-Contraction Coupling and Impairs Energetic Adaptati292
Arterial impedance as ventricular afterload.291
Right Ventricular Myocardium Derives From the Anterior Heart Field291
SDF-1α/CXCR4 Axis Is Instrumental in Neointimal Hyperplasia and Recruitment of Smooth Muscle Progenitor Cells291
Lineage and Morphogenetic Analysis of the Cardiac Valves291
Direct Evidence for Increased Hydroxyl Radicals Originating From Superoxide in the Failing Myocardium290
Endothelium-Derived Hyperpolarizing Factor Synthase (Cytochrome P450 2C9) Is a Functionally Significant Source of Reactive Oxygen Species in Coronary Arteries290
A Myocardial Nox2 Containing NAD(P)H Oxidase Contributes to Oxidative Stress in Human Atrial Fibrillation290
Neuropeptide Y290
The β 2 -Adrenergic Receptor Delivers an Antiapoptotic Signal to Cardiac Myocytes Through G i -Dependent Coupling to Phosphatidyli290
Bone Morphogenic Protein 4 Produced in Endothelial Cells by Oscillatory Shear Stress Induces Monocyte Adhesion by Stimulating Reactive Oxygen Species Production From a Nox1-Based NADPH Oxidase290
Ventricular wall stress.289
ATP-Binding Cassette Cholesterol Transporters and Cardiovascular Disease289
Transcriptional and Posttranscriptional Regulation of Endothelial Nitric Oxide Synthase Expression by Hydrogen Peroxide289
A dual function for adenosine 5'-triphosphate in the regulation of vascular tone. Excitatory cotransmitter with noradrenaline from perivascular nerves and locally released inhibitory intravascular age289
Cyclophilin A Is a Secreted Growth Factor Induced by Oxidative Stress289
Human Amyloidogenic Light Chains Directly Impair Cardiomyocyte Function Through an Increase in Cellular Oxidant Stress289
Modulation of the Ca 2 Permeable Cation Channel TRPV4 by Cytochrome P450 Epoxygenases in Vascular Endothelium289
HDL and Reverse Cholesterol Transport289
Mechanisms of glycolytic inhibition in ischemic rat hearts.288
A Concept of Negative Interstitial Pressure Based on Pressures in Implanted Perforated Capsules288
Phosphorylation of Glycogen Synthase Kinase-3β During Preconditioning Through a Phosphatidylinositol-3-Kinase–Dependent Pathway Is Cardioprotective288
Tetrahydrobiopterin Improves Endothelium-Dependent Vasodilation in Chronic Smokers288
Comparison between the sarcomere length-force relations of intact and skinned trabeculae from rat right ventricle. Influence of calcium concentrations on these relations.288
Monocyte Chemotactic Protein-1 Increases Collateral and Peripheral Conductance After Femoral Artery Occlusion287
Release of a Prostaglandin E-Like Substance from Canine Kidney by Bradykinin287
Opioid-Induced Cardioprotection Occurs via Glycogen Synthase Kinase β Inhibition During Reperfusion in Intact Rat Hearts286
Two Components of the Delayed Rectifier K + Current in Ventricular Myocytes of the Guinea Pig Type286
Glycogen Synthase Kinase-3β285
The Insulin-Like Growth Factor Axis285
Cyclic AMP Imaging in Adult Cardiac Myocytes Reveals Far-Reaching β 1 -Adrenergic but Locally Confined β 2 -Adrenergic Receptor–Me285
ATP Release From Activated Neutrophils Occurs via Connexin 43 and Modulates Adenosine-Dependent Endothelial Cell Function285
Animal models for protecting ischemic myocardium: results of the NHLBI Cooperative Study. Comparison of unconscious and conscious dog models.285
Pressure-dependent membrane depolarization in cat middle cerebral artery.284
The Myocardial Na + -H + Exchange284
Antioxidants Inhibit Nuclear Export of Telomerase Reverse Transcriptase and Delay Replicative Senescence of Endothelial Cells284
Myocardin Is a Key Regulator of CArG-Dependent Transcription of Multiple Smooth Muscle Marker Genes284
Inhibition of Extracellular Signal–Regulated Kinase Enhances Ischemia/Reoxygenation–Induced Apoptosis in Cultured Cardiac Myocytes and Exaggerates Reperfusion Injury in Isolated Perfused Heart284
Pressure-flow characteristics of coronary stenoses in unsedated dogs at rest and during coronary vasodilation.283
A redox-based O2 sensor in rat pulmonary vasculature.283
Certain Histological and Chemical Responses of the Vascular Interface to Acutely Induced Mechanical Stress in the Aorta of the Dog283
Ascorbate Prevents the Interaction of Superoxide and Nitric Oxide Only at Very High Physiological Concentrations283
Antagonism of RANTES Receptors Reduces Atherosclerotic Plaque Formation in Mice283
Estrogen Receptor α and Endothelial Nitric Oxide Synthase Are Organized Into a Functional Signaling Module in Caveolae283
Enhanced Store Overload–Induced Ca 2+ Release and Channel Sensitivity to Luminal Ca 2+ Activation Are Common Defects of RyR2 Mutat283
Mechanism of Block and Identification of the Verapamil Binding Domain to HERG Potassium Channels282
Osteopontin promotes vascular cell adhesion and spreading and is chemotactic for smooth muscle cells in vitro.282
Myocyte cell loss and myocyte cellular hyperplasia in the hypertrophied aging rat heart.282
Asymmetric Dimethylarginine and the Risk of Cardiovascular Events and Death in Patients With Coronary Artery Disease282
Autoregulation of blood flow.281
Cellular mechanisms for cardiac arrhythmias.281
Improved Assay Methods for Renin "Concentration" and "Activity" in Human Plasma281
Role of Troponin I Proteolysis in the Pathogenesis of Stunned Myocardium281
Molecular Pathway for the Localized Formation of the Sinoatrial Node281
Proinflammatory Activation of Macrophages by Basic Calcium Phosphate Crystals via Protein Kinase C and MAP Kinase Pathways281
Hydrogen Peroxide– and Peroxynitrite-Induced Mitochondrial DNA Damage and Dysfunction in Vascular Endothelial and Smooth Muscle Cells281
Simulation studies of the electrocardiogram. I. The normal heart.280
Cardiovascular Effects of Angiotensin Mediated by the Central Nervous System280
Angiotensin II and Aldosterone Regulate Gene Transcription Via Functional Mineralocortocoid Receptors in Human Coronary Artery Smooth Muscle Cells280
Inhibition of rat arterial smooth muscle cell proliferation by heparin. In vivo studies with anticoagulant and nonanticoagulant heparin.280
Hypertrophic Cardiomyopathy in Cardiac Myosin Binding Protein-C Knockout Mice280
Ionic Current Basis of Electrocardiographic Waveforms279
Influence of Mechanical, Cellular, and Molecular Factors on Collateral Artery Growth (Arteriogenesis)279
Resting membrane potential, extracellular potassium activity, and intracellular sodium activity during acute global ischemia in isolated perfused guinea pig hearts.279
Vascular Superoxide Production by NAD(P)H Oxidase279
Metabolism and excretion of nitric oxide in humans. An experimental and clinical study.279
Hypoxia Inducible Factor 1 Mediates Hypoxia-Induced TRPC Expression and Elevated Intracellular Ca 2+ in Pulmonary Arterial Smooth Muscle Cells279
Preconditioning against myocardial dysfunction after ischemia and reperfusion by an alpha 1-adrenergic mechanism.279
Inhibition of hypoxic pulmonary vasoconstriction by calcium antagonists in isolated rat lungs.278
Dysfunctional Smad Signaling Contributes to Abnormal Smooth Muscle Cell Proliferation in Familial Pulmonary Arterial Hypertension278
Diabetes Promotes Cardiac Stem Cell Aging and Heart Failure, Which Are Prevented by Deletion of the p66 shc Gene278
Control of Cerebral Circulation in Health and Disease277
Endothelial Mitochondria277
Platelets Can Associate With SARS-CoV-2 RNA and Are Hyperactivated in COVID-19277
Brain amines and models of experimental hypertension.276
Senescence and the Renal Vasculature in Normal Man276
Patterns of Atrioventricular Conduction in the Human Heart275
Preconditioning of Isolated Rat Heart Is Mediated by Protein Kinase C275
Reperfusion-induced arrhythmias and oxygen-derived free radicals. Studies with "anti-free radical" interventions and a free radical-generating system in the isolated perfused rat heart.275
The pericardium substantially affects the left ventricular diastolic pressure-volume relationship in the dog.275
Induction of Heme Oxygenase-1 Suppresses Venular Leukocyte Adhesion Elicited by Oxidative Stress275
Cytokine-Induced Modulation of Cardiac Function274
T-Tubule Function in Mammalian Cardiac Myocytes274
ACE Polymorphisms274
Superoxide dismutase plus catalase improve contractile function in the canine model of the "stunned myocardium".274
Selective attenuation of endothelium-mediated vasodilation in atherosclerotic human coronary arteries.274
Clinical Aspects of Platelet Inhibitors and Thrombus Formation272
The Electrophysiological Mechanism of Ventricular Arrhythmias in the Long QT Syndrome272
Roles of Cardiac Transcription Factors in Cardiac Hypertrophy271
Proteoglycans in Atherosclerosis and Restenosis271
The cardiac renin-angiotensin system. An appraisal of present experimental and clinical evidence.271
Fibroblast Network in Rabbit Sinoatrial Node271
Adherence in Hypertension271
Coupling of β 2 -Adrenoceptor to G i Proteins and Its Physiological Relevance in Murine Cardiac Myocytes271
Estrogen Receptor-α Mediates the Protective Effects of Estrogen Against Vascular Injury270
Transient outward current prominent in canine ventricular epicardium but not endocardium.267
The Rac and Rho Hall of Fame267
Myocyte Death in the Failing Human Heart Is Gender Dependent267
Targeted Expression of Cyclin D2 Results in Cardiomyocyte DNA Synthesis and Infarct Regression in Transgenic Mice267
Kruppel-Like Factor 2 (KLF2) Regulates Endothelial Thrombotic Function267
3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase and Isoprenylation Inhibitors Induce Apoptosis of Vascular Smooth Muscle Cells in Culture267
Regression of Coronary Atheromatosis in Rhesus Monkeys266
The distribution of blood rheological parameters in the microvasculature of cat mesentery.266
Nitric Oxide Modulates the Expression of Monocyte Chemoattractant Protein 1 in Cultured Human Endothelial Cells266
Structural and electrophysiological changes in the epicardial border zone of canine myocardial infarcts during infarct healing.266
Paracrine Regulation of Angiogenesis and Adipocyte Differentiation During In Vivo Adipogenesis266
Domain Mapping Studies Reveal That the M Domain of hsp90 Serves as a Molecular Scaffold to Regulate Akt-Dependent Phosphorylation of Endothelial Nitric Oxide Synthase and NO Release266
Distribution of Heart Potentials on the Thoracic Surface of Normal Human Subjects265
Selective inhibition of T-type Ca2+ channels by Ro 40-5967.265
Neural Crest Cells Retain Multipotential Characteristics in the Developing Valves and Label the Cardiac Conduction System265
Incidence of Myoendothelial Gap Junctions in the Proximal and Distal Mesenteric Arteries of the Rat Is Suggestive of a Role in Endothelium-Derived Hyperpolarizing Factor–Mediated Responses264
Bone Morphogenetic Proteins in Vascular Calcification263
AMP-Activated Protein Kinase in the Heart263
Activation of RhoA and Inhibition of Myosin Phosphatase as Important Components in Hypertension in Vascular Smooth Muscle263
Series of Exon-Skipping Events in the Elastic Spring Region of Titin as the Structural Basis for Myofibrillar Elastic Diversity263
Transmural myocardial deformation in the canine left ventricle. Normal in vivo three-dimensional finite strains.262
Survival of Subendocardial Purkinje Fibers after Extensive Myocardial Infarction in Dogs262
Angiotensin II Induces Monocyte Chemoattractant Protein-1 Gene Expression in Rat Vascular Smooth Muscle Cells262
Cutaneous Active Vasodilation in Humans Is Mediated by Cholinergic Nerve Cotransmission262
Rho Kinase–Mediated Vasoconstriction Is Important in Severe Occlusive Pulmonary Arterial Hypertension in Rats262
Effect of insulin on the proliferation of cultured primate arterial smooth muscle cells.261
Targeted Disruption of Kir2.1 and Kir2.2 Genes Reveals the Essential Role of the Inwardly Rectifying K + Current in K + -Mediated 261
Serum Dopamine-Beta-Hydroxylase Activity260
Brief Reviews Exchange of Calcium Ions in the Mammalian Myocardium260
Cardiac Septal and Valvular Dysmorphogenesis in Mice Heterozygous for Mutations in the Homeobox Gene Nkx2-5260
Angiotensin II and Other Hypertrophic Stimuli Mediated by G Protein–Coupled Receptors Activate Tyrosine Kinase, Mitogen-Activated Protein Kinase, and 90-kD S6 Kinase in Cardiac Myocytes260
Overexpression of Interleukin-10 by Activated T Lymphocytes Inhibits Atherosclerosis in LDL Receptor–Deficient Mice by Altering Lymphocyte and Macrophage Phenotypes260
Bone Marrow Monocyte Lineage Cells Adhere on Injured Endothelium in a Monocyte Chemoattractant Protein-1–Dependent Manner and Accelerate Reendothelialization as Endothelial Progenitor Cells260
Calcium release from the sarcoplasmic reticulum.259
Regulation of Angiopoietin-2 mRNA Levels in Bovine Microvascular Endothelial Cells by Cytokines and Hypoxia259
Heterogenous Nature of Flow-Mediated Dilatation in Human Conduit Arteries In Vivo259
Human Splanchnic and Forearm Vasoconstrictor Responses to Reductions of Right Atrial and Aortic Pressures258
Augmented responses to vasoconstrictor stimuli in hypercholesterolemic and atherosclerotic monkeys.258
Release of endogenous catecholamines in the ischemic myocardium of the rat. Part A: Locally mediated release.258
Mitochondrial Sources of H 2 O 2 Generation Play a Key Role in Flow-Mediated Dilation in Human Coronary Resistance Arteries258
Inhibition of coronary blood flow by a vascular waterfall mechanism.257
A Proposal Linking Atherogenesis to the Interaction of Endothelial Lipoprotein Lipase with Triglyceride-Rich Lipoproteins257
Tension development and sarcomere length in rat cardiac trabeculae. Evidence of length-dependent activation.257
Smooth muscle myosin heavy chain exclusively marks the smooth muscle lineage during mouse embryogenesis.257
Superoxide Anion From the Adventitia of the Rat Thoracic Aorta Inactivates Nitric Oxide257
Assessment of Passive Elastic Stiffness for Isolated Heart Muscle and the Intact Heart256
Functional and morphological organization of the rabbit sinus node.256
Elevated Sarcoplasmic Reticulum Ca 2+ Leak in Intact Ventricular Myocytes From Rabbits in Heart Failure256
Silent Information Regulator 2α, a Longevity Factor and Class III Histone Deacetylase, Is an Essential Endogenous Apoptosis Inhibitor in Cardiac Myocytes256
Inducible Expression of BNIP3 Provokes Mitochondrial Defects and Hypoxia-Mediated Cell Death of Ventricular Myocytes255
Role of the Cytosolic Chaperones Hsp70 and Hsp90 in Maturation of the Cardiac Potassium Channel hERG255
Erythrocyte and the Regulation of Human Skeletal Muscle Blood Flow and Oxygen Delivery255
NG-methyl-L-arginine, an inhibitor of L-arginine-derived nitric oxide synthesis, stimulates renal sympathetic nerve activity in vivo. A role for nitric oxide in the central regulation of sympathetic t255
Fractal nature of regional myocardial blood flow heterogeneity.254
Dimensions and Geometric Relationships of the Human Aortic Value as a Function of Pressure254
Mechanisms Underlying Conduction Slowing and Arrhythmogenesis in Nonischemic Dilated Cardiomyopathy254
Morphine Mimics the Cardioprotective Effect of Ischemic Preconditioning via a Glibenclamide-Sensitive Mechanism in the Rat Heart254
Regional myocardial function and dimensions early and late after myocardial infarction in the unanesthetized dog.254
Genetic Disruption of Poly (ADP-Ribose) Synthetase Inhibits the Expression of P-Selectin and Intercellular Adhesion Molecule-1 in Myocardial Ischemia/Reperfusion Injury254
Mechanisms of Cardiac Nerve Sprouting After Myocardial Infarction in Dogs254
Passive Stiffness Changes Caused by Upregulation of Compliant Titin Isoforms in Human Dilated Cardiomyopathy Hearts254
Upregulation of Na + /Ca 2+ Exchanger Expression and Function in an Arrhythmogenic Rabbit Model of Heart Failure254
Time-Dependent Changes in Matrix Metalloproteinase Activity and Expression During the Progression of Congestive Heart Failure254
Cardiac myocyte necrosis induced by angiotensin II.253
Influence of Right Ventricular Filling Pressure on Left Ventricular Pressure and Dimension253
Inhibition of nitric oxide production. Mechanisms of vascular albumin leakage.253
Mice With Disrupted BK Channel β1 Subunit Gene Feature Abnormal Ca 2+ Spark/STOC Coupling and Elevated Blood Pressure253
Response of the Rat Aortic Media to Hypertension252
Uncoupling Protein-2 Overexpression Inhibits Mitochondrial Death Pathway in Cardiomyocytes252
Endothelin-1–Induced Arrhythmogenic Ca 2+ Signaling Is Abolished in Atrial Myocytes of Inositol-1,4,5-Trisphosphate(IP 3 )–Recepto252
Homeometric Autoregulation in the Heart251
Electrical Restitution and Spatiotemporal Organization During Ventricular Fibrillation251
Estrogen Relaxes Coronary Arteries by Opening BK Ca Channels Through a cGMP-Dependent Mechanism251
Induced Deletion of the N-Cadherin Gene in the Heart Leads to Dissolution of the Intercalated Disc Structure251
Myocardial K ATP Channels in Preconditioning250
The Functional Anatomy of Ventricular Contraction250
Adaptations of the left ventricle to chronic pressure overload.250
Matrix Metalloproteinase-9 Is Necessary for the Regulation of Smooth Muscle Cell Replication and Migration After Arterial Injury250
Effects of norepinephrine and angiotensin II on the determinants of glomerular ultrafiltration and proximal tubule fluid reabsorption in the rat.250
Pulsatile Versus Oscillatory Shear Stress Regulates NADPH Oxidase Subunit Expression250
Endothelial Cells Modulate the Proliferation of Mural Cell Precursors via Platelet-Derived Growth Factor-BB and Heterotypic Cell Contact250
Ventricular Myocytes Are Not Terminally Differentiated in the Adult Mammalian Heart249
Allograft Vasculopathy Versus Atherosclerosis249
PPAR Activators as Antiinflammatory Mediators in Human T Lymphocytes249
Gap Junctions in Cardiovascular Disease248
Sarcoplasmic Reticulum Calcium Content Fluctuation Is the Key to Cardiac Alternans248
Long-Term Effects of Hypertension on the Rat Aortic Wall and Their Relation to Concurrent Aging Changes: MORPHOLOGICAL AND CHEMICAL STUDIES248
Left ventricular diastolic pressure-volume relations in rats with healed myocardial infarction. Effects on systolic function.248
CD40 Is Constitutively Expressed on Platelets and Provides a Novel Mechanism for Platelet Activation248
Arrhythmogenesis in Catecholaminergic Polymorphic Ventricular Tachycardia248
17β-Estradiol Reduces Cardiomyocyte Apoptosis In Vivo and In Vitro via Activation of Phospho-Inositide-3 Kinase/Akt Signaling248
Impaired CXCR4 Signaling Contributes to the Reduced Neovascularization Capacity of Endothelial Progenitor Cells From Patients With Coronary Artery Disease248
Autoantibodies against beta-adrenoceptors in human idiopathic dilated cardiomyopathy.247
Negative feedback regulation of endothelial cell function by nitric oxide.247
Correlation between cytosolic free calcium, contracture, ATP, and irreversible ischemic injury in perfused rat heart.247
CD34 /CD133 + /VEGFR-2 + Endothelial Progenitor Cell Subpopulation With Potent Vasoregenerati247
Troponin T isoform expression in humans. A comparison among normal and failing adult heart, fetal heart, and adult and fetal skeletal muscle.247
Endoplasmic Reticulum Stress Gene Induction and Protection From Ischemia/Reperfusion Injury in the Hearts of Transgenic Mice With a Tamoxifen-Regulated Form of ATF6247
Increased sheep lung vascular permeability caused by Escherichia coli endotoxin.246
Electrical uncoupling and increase of extracellular resistance after induction of ischemia in isolated, arterially perfused rabbit papillary muscle.246
Action potential prolongation and induction of abnormal automaticity by low quinidine concentrations in canine Purkinje fibers. Relationship to potassium and cycle length.246
Functional, morphological, and metabolic abnormalities of the cerebral microcirculation after concussive brain injury in cats.246
Differential Distribution of Electrophysiologically Distinct Myocytes in Conduit and Resistance Arteries Determines Their Response to Nitric Oxide and Hypoxia246
Cells Expressing Early Cardiac Markers Reside in the Bone Marrow and Are Mobilized Into the Peripheral Blood After Myocardial Infarction246
Trafficking of G Protein–Coupled Receptors245
Instantaneous pressure-volume relationship of the canine right ventricle.245
Inhibition of rat arterial smooth muscle cell proliferation by heparin. II. In vitro studies.245
Effect of increased vascular pressure on lung fluid balance in unanesthetized sheep.245
Nitric Oxide Induces Heme Oxygenase-1 Gene Expression and Carbon Monoxide Production in Vascular Smooth Muscle Cells245
Cell-to-Cell Connection of Endothelial Progenitor Cells With Cardiac Myocytes by Nanotubes245
β-Adrenergic Enhancement of Sarcoplasmic Reticulum Calcium Leak in Cardiac Myocytes Is Mediated by Calcium/Calmodulin-Dependent Protein Kinase245
Hypoxia-Inducible Factor-1 Mediates Activation of Cultured Vascular Endothelial Cells by Inducing Multiple Angiogenic Factors244
Interrelationships Between Automaticity and Conduction in Purkinje Fibers244
Vascular Matrix Metalloproteinase-2 Cleaves Big Endothelin-1 Yielding a Novel Vasoconstrictor244
Impaired endothelium-dependent relaxation to aggregating platelets and related vasoactive substances in porcine coronary arteries in hypercholesterolemia and atherosclerosis.244
cAMP-Specific Phosphodiesterase-4 Enzymes in the Cardiovascular System244
Embryonic Endothelial Cells Transdifferentiate Into Mesenchymal Cells Expressing Smooth Muscle Actins In Vivo and In Vitro244
Effect of reperfusion late in the phase of reversible ischemic injury. Changes in cell volume, electrolytes, metabolites, and ultrastructure.244
Double-Edged Role of Statins in Angiogenesis Signaling243
Isolation of gene markers of differentiated and proliferating vascular smooth muscle cells.243
Nitric oxide mediates vasodilatation in response to activation of N-methyl-D-aspartate receptors in brain.243
Tumor Necrosis Factor-α Induces Endothelial Dysfunction in the Prediabetic Metabolic Syndrome243
A Novel Signal Transduction Cascade Involving Direct Physical Interaction of the Renin/Prorenin Receptor With the Transcription Factor Promyelocytic Zinc Finger Protein243
Altered myocardial mechanics in diabetic rats.242
Signal transduction pathways of angiotensin II--induced c-fos gene expression in cardiac myocytes in vitro. Roles of phospholipid-derived second messengers.242
8-bromo-cGMP reduces the myofilament response to Ca2+ in intact cardiac myocytes.242
Angiogenesis Inhibitor, TNP-470, Prevents Diet-Induced and Genetic Obesity in Mice242
Impaired diastolic function and coronary reserve in genetic hypertension. Role of interstitial fibrosis and medial thickening of intramyocardial coronary arteries.241
Diversity in Mitochondrial Function Explains Differences in Vascular Oxygen Sensing241
Independent Signals Control Expression of the Calcineurin Inhibitory Proteins MCIP1 and MCIP2 in Striated Muscles241
Altered Patterns of Gene Expression in Response to Myocardial Infarction241
Contribution of endogenous endothelin-1 to the progression of cardiopulmonary alterations in rats with monocrotaline-induced pulmonary hypertension.241
Length-Tension Relationship of Smooth Muscle of the Hog Carotid Artery241
Distinct Phenotype of E-Selectin–Deficient Mice241
Free Radicals, Mitochondria, and Oxidized Lipids241
Molecular Mechanisms of Coronary Collateral Vessel Growth240
Ventriculoarterial coupling in normal and failing heart in humans.240
Caveolae and Caveolins in the Cardiovascular System240
Developmental Control of Titin Isoform Expression and Passive Stiffness in Fetal and Neonatal Myocardium240
Angiotensin II is mitogenic in neonatal rat cardiac fibroblasts.240
Extracellular potentials related to intracellular action potentials during impulse conduction in anisotropic canine cardiac muscle.240
Accumulation of unesterified arachidonic acid in ischemic canine myocardium. Relationship to a phosphatidylcholine deacylation-reacylation cycle and the depletion of membrane phospholipids.240
Ca 2+ -Dependent Activation of Rho and Rho Kinase in Membrane Depolarization–Induced and Receptor Stimulation–Induced Vascular Smooth Muscle Contraction240
Phospholamban: A Prominent Regulator of Myocardial Contractility239
Modulation of Mitochondrial ATP-Dependent K + Channels by Protein Kinase C239
Role of Specific Glycopeptides of Human Serum Lipoproteins in the Activation of Lipoprotein Lipase239
Diastolic-systolic coronary flow differences are caused by intramyocardial pump action in the anesthetized dog.239
Angiotensin II Induces Apoptosis of Human Endothelial Cells239
Effect of positive inotropic agents on the relation between oxygen consumption and systolic pressure volume area in canine left ventricle.239
Effects of acutely induced hypertension in cats on pial arteriolar caliber, local cerebral blood flow, and the blood-brain barrier.239
Bone Morphogenetic Protein Receptor-2 Signaling Promotes Pulmonary Arterial Endothelial Cell Survival239
Transmural Electrophysiological Heterogeneities Underlying Arrhythmogenesis in Heart Failure238
Diminished inotropic response of aged myocardium to catecholamines.238
Observations on the Extrinsic Neural Control of Cerebral Blood Flow in the Baboon238
Nitric Oxide Reversibly Inhibits the Migration of Cultured Vascular Smooth Muscle Cells238
Shear stress-induced reorganization of the surface topography of living endothelial cells imaged by atomic force microscopy.238
Angiotensin II Induces Interleukin-6 Transcription in Vascular Smooth Muscle Cells Through Pleiotropic Activation of Nuclear Factor-κB Transcription Factors238
Intrarenal Distribution of Nutrient Blood Flow Determined with Krypton 85 in the Unanesthetized Dog238
Multiple pathways of capillary permeability.237
Acute Fulminating Neurogenic Hypertension Produced by Brainstem Lesions in the Rat237
Capillary perfusion of the rat brain cortex. An in vivo confocal microscopy study.237
Young Adult Bone Marrow–Derived Endothelial Precursor Cells Restore Aging-Impaired Cardiac Angiogenic Function237
Glucocorticoid Excess Induces Superoxide Production in Vascular Endothelial Cells and Elicits Vascular Endothelial Dysfunction237
High-Mobility Group Box 1 Activates Integrin-Dependent Homing of Endothelial Progenitor Cells237
Hypercontractile Female Hearts Exhibit Increased S -Nitrosylation of the L-Type Ca 2+ Channel α1 Subunit and Reduced Ischemia/Reperfus237
Cardiac Myosin Binding Protein C236
Protein kinase C. Its role in ischemic preconditioning in the rat.236
Ca 2+ Handling and Sarcoplasmic Reticulum Ca 2+ Content in Isolated Failing and Nonfailing Human Myocardium236
Identity of a novel delayed rectifier current from human heart with a cloned K+ channel current.236
Transient Receptor Potential Vanilloid 4–Mediated Disruption of the Alveolar Septal Barrier236
Brief Reviews : A Systems Analysis Approach to Understanding Long-Range Arterial Blood Pressure Control and Hypertension236
Bradycardia and Slowing of the Atrioventricular Conduction in Mice Lacking Ca V 3.1/α 1G T-Type Calcium Channels236
Two-Photon Microscopy of Cells and Tissue234
Stem Cells for Myocardial Regeneration234
Triggered activity in cardiac muscle fibers of the simian mitral valve.234
Examination of the Transverse Tubular System in Living Cardiac Rat Myocytes by 2-Photon Microscopy and Digital Image–Processing Techniques234
Heart Valve Tissue Engineering233
Molecular Determinants of Vascular Smooth Muscle Cell Diversity233
The left ventricular dP/dtmax-end-diastolic volume relation in closed-chest dogs.233
Adipocyte Signaling and Lipid Homeostasis233
Death by Design233
Nature of Species Differences in the Medial Distribution of Aortic Vasa Vasorum in Mammals233
Diverse Contribution of Bone Marrow Cells to Neointimal Hyperplasia After Mechanical Vascular Injuries233
Evidence of the Limitations of Water as a Freely Diffusible Tracer in Brain of the Rhesus Monkey233
Chronic treatment with polyethylene-glycolated superoxide dismutase partially restores endothelium-dependent vascular relaxations in cholesterol-fed rabbits.233
VEGFR-1–Selective VEGF Homologue PlGF Is Arteriogenic233
Collagen expression in mechanically stimulated cardiac fibroblasts.232
Molecular mechanisms of nitric oxide regulation. Potential relevance to cardiovascular disease.232
Virtual Electrode–Induced Phase Singularity232
Disruption of Hemoglobin Oxygen Transport Does Not Impact Oxygen-Dependent Physiological Processes in Developing Embryos of Zebra Fish ( Danio rerio )232
Protein Kinase A Phosphorylates Titin’s Cardiac-Specific N2B Domain and Reduces Passive Tension in Rat Cardiac Myocytes232
Contractile State of the Left Ventricle in Man232
Formation of the Venous Pole of the Heart From an Nkx2–5 –Negative Precursor Population Requires Tbx18232
Enhanced Postischemic Functional Recovery in CYP2J2 Transgenic Hearts Involves Mitochondrial ATP-Sensitive K + Channels and p42/p44 MAPK Pathway232
Mechanism of preconditioning. Ionic alterations.231
Ubiquitin and Ubiquitin-Like Proteins in Protein Regulation231
Electrophysiological changes and ventricular arrhythmias in the early phase of regional myocardial ischemia.231
Isoproterenol-induced myocardial fibrosis in relation to myocyte necrosis.231
Mitochondrial Reactive Oxygen Species Trigger Calcium Increases During Hypoxia in Pulmonary Arterial Myocytes231
Endothelial Nuclear Patterns in the Canine Arterial Tree with Particular Reference to Hemodynamic Events231
Production of 20-HETE and Its Role in Autoregulation of Cerebral Blood Flow231
High Basal Protein Kinase A–Dependent Phosphorylation Drives Rhythmic Internal Ca 2+ Store Oscillations and Spontaneous Beating of Cardiac Pacemaker Cells231
Ischemic Preconditioning Activates Phosphatidylinositol-3-Kinase Upstream of Protein Kinase C230
Quantitative Assessment of the SR Ca 2+ Leak-Load Relationship230
Heterogeneity of Expression of E- and P-Selectins In Vivo230
Comparison of the Effects of Anoxia and Whole Heart Ischemia on Carbohydrate Utilization in Isolated Working Rat Hearts230
Nitric Oxide Enhances Angiogenesis via the Synthesis of Vascular Endothelial Growth Factor and cGMP After Stroke in the Rat230
Treatment With Dimethylthiourea Prevents Left Ventricular Remodeling and Failure After Experimental Myocardial Infarction in Mice230
Early Signals in Cardiac Development229
Control of maximum rates of glycolysis in rat cardiac muscle.229
Sarcoplasmic reticulum gene expression in cardiac hypertrophy and heart failure.229
Troponin and Tropomyosin229
Porcine coronary arteries with regenerated endothelium have a reduced endothelium-dependent responsiveness to aggregating platelets and serotonin.229
Activation of the Unfolded Protein Response in Infarcted Mouse Heart and Hypoxic Cultured Cardiac Myocytes229
Compartmentalized Phosphodiesterase-2 Activity Blunts β-Adrenergic Cardiac Inotropy via an NO/cGMP-Dependent Pathway229
Interstitial Fluid Pressure: II. Pressure-Volume Curves of Interstitial Space228
Morphological and Molecular Characterization of Adult Cardiomyocyte Apoptosis During Hypoxia and Reoxygenation228
Role of Calcium Cycling Versus Restitution in the Mechanism of Repolarization Alternans228
Side-to-side slippage of myocytes participates in ventricular wall remodeling acutely after myocardial infarction in rats.228
Desmosomal Dysfunction due to Mutations in Desmoplakin Causes Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy228
Alpha B-crystallin in cardiac tissue. Association with actin and desmin filaments.227
Changes in central catecholaminergic neurons in the spontaneously (genetic) hypertensive rat.227
Familial Hypertrophic Cardiomyopathy227
The Cardiac Renin-Angiotensin System227
Intussusceptive Angiogenesis227
Role of endothelial cell cytoskeleton in control of endothelial permeability.227
Calcium channels in muscle cells isolated from rat mesenteric arteries: modulation by dihydropyridine drugs.227
Perivascular Potassium and pH as Determinants of Local Pial Arterial Diameter in Cats227
Actions of sympathomimetic amines on the Ca2+ transients and contractions of rabbit myocardium: reciprocal changes in myofibrillar responsiveness to Ca2+ mediated through alpha- and beta-adrenoceptors227
Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) Expression Is Decreased in Pulmonary Hypertension and Affects Endothelial Cell Growth227
Interstitial Flow as a Guide for Lymphangiogenesis226
Impaired Conduction of Vasodilation Along Arterioles in Connexin40-Deficient Mice226
Two Distinct Congenital Arrhythmias Evoked by a Multidysfunctional Na + Channel226
High-Resolution Electrophysiological Assessment of Human Embryonic Stem Cell-Derived Cardiomyocytes226
Estrogen Upregulates Endothelial Nitric Oxide Synthase Gene Expression in Fetal Pulmonary Artery Endothelium226
Alpha 1-adrenergic and muscarinic cholinergic stimulation of phosphoinositide hydrolysis in adult rat cardiomyocytes.225
Distribution and Prevalence of Hyperpolarization-Activated Cation Channel (HCN) mRNA Expression in Cardiac Tissues225
Altered Expression of Small-Conductance Ca 2+ -Activated K + (SK3) Channels Modulates Arterial Tone and Blood Pressure225
Human Mesenchymal Stem Cells as a Gene Delivery System to Create Cardiac Pacemakers225
Functional Coupling Between Glycolysis and Sarcoplasmic Reticulum Ca 2+ Transport224
Aberrant A-V Impulse Propagation in the Dog Heart: A Study of Functional Bundle Branch Block224
Canine ventricular arrhythmias in the late myocardial infarction period. 8. Epicardial mapping of reentrant circuits.224
Measurements of coronary velocity and reactive hyperemia in the coronary circulation of humans.224
Antiarrhythmic Engineering of Skeletal Myoblasts for Cardiac Transplantation224
Exogenous High-Mobility Group Box 1 Protein Induces Myocardial Regeneration After Infarction via Enhanced Cardiac C-Kit + Cell Proliferation and Differentiation224
Comparison of Abdominal and Thoracic Aortic Medial Structure in Mammals223
Arterial Endothelium-Specific Activin Receptor-Like Kinase 1 Expression Suggests Its Role in Arterialization and Vascular Remodeling223
Matrix Metalloproteinase Inhibition During the Development of Congestive Heart Failure223
Cardiac Innervation and Sudden Cardiac Death223
Organelle Proteomics222
Selective changes in cardiac gene expression during compensated hypertrophy and the transition to cardiac decompensation in rats with chronic aortic banding.222
Protein Kinase G Transmits the Cardioprotective Signal From Cytosol to Mitochondria222
Contraction-excitation feedback in myocardium. Physiological basis and clinical relevance.221
Transient outward current in human ventricular myocytes of subepicardial and subendocardial origin.221
Dual control of relaxation. Its role in the ventricular function in the mammalian heart.221
Voltage-Gated K + Currents Regulate Resting Membrane Potential and [Ca 2+ ] i in Pulmonary Arte221
Inducible Expression of Lectin-like Oxidized LDL Receptor-1 in Vascular Endothelial Cells221
Human smooth muscle myosin heavy chain isoforms as molecular markers for vascular development and atherosclerosis.221
B-Type Natriuretic Peptide Exerts Broad Functional Opposition to Transforming Growth Factor-β in Primary Human Cardiac Fibroblasts221
Age-Dependent Impairment of Endothelial Progenitor Cells Is Corrected by Growth Hormone Mediated Increase of Insulin-Like Growth Factor-1221
Novel Vascular Graft Grown Within Recipient’s Own Peritoneal Cavity220
Cyclic guanosine monophosphate inhibition of contraction may be mediated through inhibition of phosphatidylinositol hydrolysis in rat aorta.220
Effects of excess free fatty acids on mechanical and metabolic function in normal and ischemic myocardium in swine.220
Oxidized low density lipoproteins induce mRNA expression and release of endothelin from human and porcine endothelium.220
Angiotensin II Activates Nuclear Transcription Factor κB Through AT 1 and AT 2 in Vascular Smooth Muscle Cells220
Uncontrolled Expression of Vascular Endothelial Growth Factor and Its Receptors Leads to Insufficient Skin Angiogenesis in Patients With Systemic Sclerosis220
Capillary fluid filtration. Starling forces and lymph flow.219
Cardiac Troponin I Phosphorylation Increases the Rate of Cardiac Muscle Relaxation219
Sarcoplasmic Reticulum Ca 2+ and Heart Failure219
NADH Oxidase Activation Is Involved in Arsenite-Induced Oxidative DNA Damage in Human Vascular Smooth Muscle Cells219
Association Between a Functional Variant of the KLOTHO Gene and High-Density Lipoprotein Cholesterol, Blood Pressure, Stroke, and Longevity219
Increased Expression of Cytoskeletal, Linkage, and Extracellular Proteins in Failing Human Myocardium219
The wavelength of the cardiac impulse and reentrant arrhythmias in isolated rabbit atrium. The role of heart rate, autonomic transmitters, temperature, and potassium.219
Transplantation of Blood-Derived Progenitor Cells After Recanalization of Chronic Coronary Artery Occlusion219
Input Impedance of the Systemic Circulation218
Electrophysiological Properties of Canine Purkinje Cells in One-Day-Old Myocardial Infarction218
Molecular Determinants of Dofetilide Block of HERG K + Channels218
Involvement of Myoendothelial Gap Junctions in the Actions of Endothelium-Derived Hyperpolarizing Factor218
Etomoxir, a carnitine palmitoyltransferase I inhibitor, protects hearts from fatty acid-induced ischemic injury independent of changes in long chain acylcarnitine.218
Alterations in cardiac gene expression during the transition from stable hypertrophy to heart failure. Marked upregulation of genes encoding extracellular matrix components.218
Dimensions of Blood Vessels from Distributing Artery to Collecting Vein217
Comparative Evaluation of FGF-2–, VEGF-A–, and VEGF-C–Induced Angiogenesis, Lymphangiogenesis, Vascular Fenestrations, and Permeability217
The Stromal Cell–Derived Factor-1 Chemokine Is a Potent Platelet Agonist Highly Expressed in Atherosclerotic Plaques217
Notch Activation Results in Phenotypic and Functional Changes Consistent With Endothelial-to-Mesenchymal Transformation217
Two Isoforms of the Mouse Ether-a-go-go –Related Gene Coassemble to Form Channels With Properties Similar to the Rapidly Activating Component of the Cardiac Delayed Rect217
Regulation of Gene Expression by Cyclic GMP216
Role of nitric oxide in the regulation of oxygen consumption in conscious dogs.216
Phenotypic Alteration of Vascular Smooth Muscle Cells Precedes Elastolysis in a Mouse Model of Marfan Syndrome216
Brain Natriuretic Peptide Is Produced in Cardiac Fibroblasts and Induces Matrix Metalloproteinases216
Intermittent Hypoxia Induces Hyperlipidemia in Lean Mice216
Early Growth Response-1 in Cardiovascular Pathobiology215
Effect of Coronary Vasodilator Drugs on Retrograde Flow in Areas of Chronic Myocardial Ischemia215
Regulation of Vascular Calcification215
Intracellular oxidative stress induced by nitric oxide synthesis inhibition increases endothelial cell adhesion to neutrophils.215
Antisense Oligodeoxynucleotides Directed Against Kv1.5 mRNA Specifically Inhibit Ultrarapid Delayed Rectifier K + Current in Cultured Adult Human Atrial Myocytes215
Interaction between endothelin-1 and endothelium-derived relaxing factor in human arteries and veins.215
Upregulation of Endothelial Receptor for Oxidized Low-Density Lipoprotein (LOX-1) in Cultured Human Coronary Artery Endothelial Cells by Angiotensin II Type 1 Receptor Activation215
High-Density Lipoprotein Promotes Endothelial Cell Migration and Reendothelialization via Scavenger Receptor-B Type I215
Phenotyping Hypertrophy214
Effect of Nitroglycerin and Dipyridamole on Regional Coronary Resistance214
Electrical Coupling Between Endothelial Cells and Smooth Muscle Cells in Hamster Feed Arteries214
Relation between transmural deformation and local myofiber direction in canine left ventricle.214
Neural Crest Cell Contribution to the Developing Circulatory System214
Cerebral Blood Flow In Man at High Altitude214
Pharmacological mechanisms for left ventricular unloading in clinical congestive heart failure. Differential effects of nitroprusside, phentolamine, and nitroglycerin on cardiac function and periphera214
Cyclic GMP-Dependent Protein Kinases and the Cardiovascular System213
3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors Interfere With Angiogenesis by Inhibiting the Geranylgeranylation of RhoA213
Nuclear Factor-κB Plays an Essential Role in the Late Phase of Ischemic Preconditioning in Conscious Rabbits213
Mechanism of Nitric Oxide–Induced Vasodilatation213
Design Principles of Vascular Beds212
Primary role of renal homografts in setting chronic blood pressure levels in rats.212
A Sensitive Double-Isotope Derivative Assay for Norepinephrine and Epinephrine212
Cardiomyocyte Cultures With Controlled Macroscopic Anisotropy212
Hypoxic Regulation of Inducible Nitric Oxide Synthase via Hypoxia Inducible Factor-1 in Cardiac Myocytes212
Vasoactive Substances Regulate Vascular Smooth Muscle Cell Apoptosis212
Class III Antiarrhythmic Drugs Block HERG, a Human Cardiac Delayed Rectifier K + Channel212
The Extracellular Matrix in Ischemic and Nonischemic Heart Failure212
L-Type Ca 2+ Channel Density and Regulation Are Altered in Failing Human Ventricular Myocytes and Recover After Support With Mechanical Assist Devices212
Blood Supply of the Myocardium after Temporary Coronary Occlusion211
Role of shear stress and endothelial prostaglandins in flow- and viscosity-induced dilation of arterioles in vitro.211
Differential Expression of Adenosine Receptors in Human Endothelial Cells211
Endothelial NADPH Oxidase as the Source of Oxidants in Lungs Exposed to Ischemia or High K +211
Pulmonary Hypertension in Transgenic Mice Expressing a Dominant-Negative BMPRII Gene in Smooth Muscle211
Nitric Oxide Activates Telomerase and Delays Endothelial Cell Senescence210
Troponin I Degradation and Covalent Complex Formation Accompanies Myocardial Ischemia/Reperfusion Injury210
Transverse Shear Along Myocardial Cleavage Planes Provides a Mechanism for Normal Systolic Wall Thickening210
Effect of reduced aortic compliance on cardiac efficiency and contractile function of in situ canine left ventricle.210
Molecular determinants of reperfusion-induced leukocyte adhesion and vascular protein leakage.210
Neurovascular and Cognitive Dysfunction in Hypertension210
Interaction of Vasopressin and the Baroreceptor Reflex System in the Regulation of Arterial Blood Pressure in the Dog209
Effect of Verapamil on the Sinoatrial and Atrioventricular Nodes of the Rabbit and the Mechanism by Which it Arrests Reentrant Atrioventricular Nodal Tachycardia209
Ca 2+ /Calmodulin-Dependent Protein Kinase II Phosphorylation of Ryanodine Receptor Does Affect Calcium Sparks in Mouse Ventricular Myocytes209
Regulation of Matrix Metalloproteinase Expression in Human Vascular Smooth Muscle Cells by T Lymphocytes209
Function of the sarcoplasmic reticulum and expression of its Ca2(+)-ATPase gene in pressure overload-induced cardiac hypertrophy in the rat.209
Expression of Constitutive and Inducible Nitric Oxide Synthases in the Vascular Wall of Young and Aging Rats209
Impaired Endothelium-Derived Hyperpolarizing Factor-Mediated Dilations and Increased Blood Pressure in Mice Deficient of the Intermediate-Conductance Ca 2+ -Activate209
Diastolic coronary artery pressure-flow relations in the dog.208
Release of Adenosine by the Normal Myocardium in Dogs and Its Relationship to the Regulation of Coronary Resistance208
Stimulation of soluble guanylate cyclase by an acetylcholine-induced endothelium-derived factor from rabbit and canine arteries.208
Immunohistochemical and biochemical evidence for a cardiovascular mineralocorticoid receptor.208
Effects of Agents which Inhibit the Slow Channel on Sinus Node Automaticity and Atrioventricular Conduction in the Dog208
Time course of smooth muscle cell proliferation in the intima and media of arteries following experimental angioplasty.208
Heparin-II Domain of Fibronectin Is a Vascular Endothelial Growth Factor-Binding Domain208
The cardiac hypertrophy process. Analyses of factors determining pathological vs. physiological development.207
Integrative Analysis of Calcium Cycling in Cardiac Muscle207
Bone Marrow–Derived Cells for Enhancing Collateral Development207
Role of the Pressor Action of Angiotensin IIin Experimental Hypertension207
Heme Oxygenase-1–Derived Carbon Monoxide Contributes to the Suppression of Acute Hypertensive Responses In Vivo207
Mechanisms of sinoatrial pacemaker synchronization: a new hypothesis.206
Homocysteine Thiolactone and Protein Homocysteinylation in Human Endothelial Cells206
Sarcoplasmic Reticulum Ca 2+ Release Causes Myocyte Depolarization206
Reengineering Inducible Cardiac-Specific Transgenesis With an Attenuated Myosin Heavy Chain Promoter206
Identification and Expression of δ-Isoforms of the Multifunctional Ca 2+ /Calmodulin-Dependent Protein Kinase in Failing and Nonfailing Human Myocardium206
Distribution of Size and Shape in Populations of Normal Human Red Cells205
Amiloride delays the ischemia-induced rise in cytosolic free calcium.205
Turbulent blood flow in the ascending aorta of humans with normal and diseased aortic valves.205
Contractile State of the Heart Characterized by Force-Velocity Relations in Variably Afterloaded and Isovolumic Beats205
Role of Caspases in Ox-LDL–Induced Apoptotic Cascade in Human Coronary Artery Endothelial Cells205
Monocyte/Macrophage Suppression in CD11b Diphtheria Toxin Receptor Transgenic Mice Differentially Affects Atherogenesis and Established Plaques205
3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors Increase Fibrinolytic Activity in Rat Aortic Endothelial Cells205
Gene Expression Patterns in the Lungs of Patients With Primary Pulmonary Hypertension205
Bidirectional Ventricular Tachycardia and Fibrillation Elicited in a Knock-In Mouse Model Carrier of a Mutation in the Cardiac Ryanodine Receptor205
Potential Antiatherogenic Mechanisms of Ascorbate (Vitamin C) and α-Tocopherol (Vitamin E)204
Work as a correlate of canine left ventricular oxygen consumption, and the problem of catecholamine oxygen wasting.204
Procoagulant Soluble Tissue Factor Is Released From Endothelial Cells in Response to Inflammatory Cytokines204
Mechanical Stretch Activates the JAK/STAT Pathway in Rat Cardiomyocytes204
Expression of beta-arrestins and beta-adrenergic receptor kinases in the failing human heart.204
Thioredoxin-2 Inhibits Mitochondria-Located ASK1-Mediated Apoptosis in a JNK-Independent Manner204
Bradykinin-induced increases in cytosolic calcium and ionic currents in cultured bovine aortic endothelial cells.204
Altered Myocardial Function and Metabolism in Chronic Diabetes Mellitus without Ischemia in Dogs204
Transient and Prolonged Increase in Endothelial Permeability Induced by Histamine and Thrombin204
Induction of Bone-Type Alkaline Phosphatase in Human Vascular Smooth Muscle Cells204
Angiogenesis and Pericytes in the Initiation of Ectopic Calcification203
Renal Myogenic Response203
Effect of electrotonic potentials on pacemaker activity of canine Purkinje fibers in relation to parasystole.203
Mechanical Properties of Rat Cardiac Muscle during Experimental Hypertrophy203
Molecular Mechanisms Underlying Ionic Remodeling in a Dog Model of Atrial Fibrillation203
Long-Term Vitamin C Treatment Increases Vascular Tetrahydrobiopterin Levels and Nitric Oxide Synthase Activity203
Preconditioning in Cardiomyocytes Protects by Attenuating Oxidant Stress at Reperfusion203
Spatial Heterogeneity of Endothelial Phenotypes Correlates With Side-Specific Vulnerability to Calcification in Normal Porcine Aortic Valves203
Pharmacologic treatment of hyperlipidemia reduces glomerular injury in rat 5/6 nephrectomy model of chronic renal failure.203
Multiple Mechanisms of Na + Channel– Linked Long-QT Syndrome203
The Protective Effect of Late Preconditioning Against Myocardial Stunning in Conscious Rabbits Is Mediated by Nitric Oxide Synthase203
Mitophagy Is Essential for Maintaining Cardiac Function During High Fat Diet-Induced Diabetic Cardiomyopathy203
Mice Lacking the Vascular Endothelial Growth Factor-B Gene ( Vegfb ) Have Smaller Hearts, Dysfunctional Coronary Vasculature, and Impaired Recovery From Cardiac Ischemia203
Early outward current in rat single ventricular cells.202
Input impedance of the systemic circulation in man.202
Dual Adrenergic and Cholinergic Innervation of the Cerebral Arteries of the Rat202
Alpha-skeletal muscle actin mRNA's accumulate in hypertrophied adult rat hearts.202
Alterations in vascular smooth muscle mass in the spontaneously hypertensive rat. Role of cellular hypertrophy, hyperploidy, and hyperplasia.202
Spontaneous and Induced Cardiac Arrhythmias in Subendocardial Purkinje Fibers Surviving Extensive Myocardial Infarction in Dogs202
Modulation of Cardiac Gap Junction Expression and Arrhythmic Susceptibility202
Angiotensin II Impairs Neurovascular Coupling in Neocortex Through NADPH Oxidase–Derived Radicals202
Cardiac Microstructure202
Uptake and tissue content of fatty acids in dog myocardium under normoxic and ischemic conditions.202
Serotonin Increases Susceptibility to Pulmonary Hypertension in BMPR2 -Deficient Mice202
Engineering Myocardial Tissue202
Vascular Remodeling in Transplant Vasculopathy201
Localization of Sodium Channels in Intercalated Disks Modulates Cardiac Conduction201
At the Crossroads of Myocardial Signaling201
The behavior of sonicated albumin microbubbles within the microcirculation: a basis for their use during myocardial contrast echocardiography.201
Wave-front curvature as a cause of slow conduction and block in isolated cardiac muscle.201
Cardiomyocyte-Specific Knockout and Agonist of Peroxisome Proliferator–Activated Receptor-γ Both Induce Cardiac Hypertrophy in Mice201
Mechanism of ventricular vulnerability to single premature stimuli in open-chest dogs.201
Constitutive Endocytosis of CD163 Mediates Hemoglobin-Heme Uptake and Determines the Noninflammatory and Protective Transcriptional Response of Macrophages to Hemoglobin201
Cardiac Neuronal Nitric Oxide Synthase Isoform Regulates Myocardial Contraction and Calcium Handling201
Recent Developments in Vascular Endothelial Cell Transient Receptor Potential Channels200
Purkinje-Muscle Reentry as a Mechanism of Polymorphic Ventricular Arrhythmias in a 3-Dimensional Model of the Ventricles200
Myosin isoenzymes in normal and hypertrophied human ventricular myocardium.200
Tissue-specific determinants of anisotropic conduction velocity in canine atrial and ventricular myocardium.200
Genetically Determined Heterogeneity in Hemoglobin Scavenging and Susceptibility to Diabetic Cardiovascular Disease200
Reassessing the Mechanisms of Acute Coronary Syndromes200
Mouse model of arterial injury.199
Angiotensin-Converting Enzyme II in the Heart and the Kidney199
Structure, Regulation, and Function of Mammalian Membrane Guanylyl Cyclase Receptors, With a Focus on Guanylyl Cyclase-A199
Superoxide Mediates Sympathoexcitation in Heart Failure199
Monocyte Chemoattractant Protein-1 Induces a Novel Transcription Factor That Causes Cardiac Myocyte Apoptosis and Ventricular Dysfunction199
Point-Counterpoint of Sphingosine 1-Phosphate Metabolism198
Myocardin-Related Transcription Factors198
Calcium-Dependent Action Potentials Produced by Catecholamines in Guinea Pig Atrial Muscle Fibers Depolarized by Potassium198
Chronic exercise enhances endothelium-mediated dilation of epicardial coronary artery in conscious dogs.198
Shear Stress Modulates Expression of Cu/Zn Superoxide Dismutase in Human Aortic Endothelial Cells198
Heme Oxygenase-1 Inhibits Atherosclerotic Lesion Formation in LDL-Receptor Knockout Mice198
Development of the cardiac coronary vascular endothelium, studied with antiendothelial antibodies, in chicken-quail chimeras.198
Relation of Ultrastructure to Function in the Intact Heart: Sarcomere Structure Relative to Pressure Volume Curves of Intact Left Ventricles of Dog and Cat198
Influence of the passive anisotropic properties on directional differences in propagation following modification of the sodium conductance in human atrial muscle. A model of reentry based on anisotrop198
A Cardiac Sodium Channel Mutation Cosegregates With a Rare Connexin40 Genotype in Familial Atrial Standstill198
Translocation of Connexin 43 to the Inner Mitochondrial Membrane of Cardiomyocytes Through the Heat Shock Protein 90–Dependent TOM Pathway and Its Importance for Cardioprotection198
Focal Adhesions197
Coronary Hemodynamics in Endothelial NO Synthase Knockout Mice197
The Mitochondrial Apoptotic Pathway Is Activated by Serum and Glucose Deprivation in Cardiac Myocytes197
Smooth muscle cells express urokinase during mitogenesis and tissue-type plasminogen activator during migration in injured rat carotid artery.197
Transgenic Model of Aldosterone-Driven Cardiac Hypertrophy and Heart Failure197
Measurement of Myocardial Blood Flow in Animals and Man by Selective Injection of Radioactive Inert Gas into the Coronary Arteries197
Appearance of superoxide anion radical in cerebral extracellular space during increased prostaglandin synthesis in cats.197
Diabetic Cardiomyopathy197
Targeted Disruption of cd73 /Ecto-5′-Nucleotidase Alters Thromboregulation and Augments Vascular Inflammatory Response197
Transcriptional Regulation of Vertebrate Cardiac Morphogenesis196
Hypoxia-Induced Inhibition of Adenosine Kinase Potentiates Cardiac Adenosine Release196
Evidence for increased media thickness, increased neuronal amine uptake, and depressed excitation--contraction coupling in isolated resistance vessels from essential hypertensives.196
Role of Small GTPases in Endothelial Cytoskeletal Dynamics and the Shear Stress Response195
Mechanism of S-T Segment Alteration During Acute Myocardial Injury195
Hydroxyl Radical Inhibits Sarcoplasmic Reticulum Ca 2+ -ATPase Function by Direct Attack on the ATP Binding Site195
Proliferation in primary and restenotic coronary atherectomy tissue. Implications for antiproliferative therapy.195
Novel Vascular Endothelial Growth Factor Binding Domains of Fibronectin Enhance Vascular Endothelial Growth Factor Biological Activity195
Effect of Coronary Perfusion Pressure or Coronary Flow on Oxygen Usage of the Myocardium194
T-type Ca2+ current is expressed in hypertrophied adult feline left ventricular myocytes.194
Direct measurement of changes in intracellular calcium transients during hypoxia, ischemia, and reperfusion of the intact mammalian heart.194
Uneven distribution of postjunctional alpha 1-and alpha 2-like adrenoceptors in canine arterial and venous smooth muscle.194
Hemodynamic Regulation of Tumor Necrosis Factor-α Gene and Protein Expression in Adult Feline Myocardium194
Responses of Coronary Smooth Muscle to Catecholamines193
Granulocytes cause reperfusion ventricular dysfunction after 15-minute ischemia in the dog.193
Fluid Shear Stress Stimulates Mitogen-Activated Protein Kinase in Endothelial Cells193
Engineering Mechanics for Successive States in Canine Left Ventricular Myocardium193
CD36 Deficiency Rescues Lipotoxic Cardiomyopathy193
Gap Junctions in Vascular Tissues193
Importance of CXC Chemokine Receptor 2 in the Homing of Human Peripheral Blood Endothelial Progenitor Cells to Sites of Arterial Injury193
Reduced Nitric Oxide Production and Altered Myocardial Metabolism During the Decompensation of Pacing-Induced Heart Failure in the Conscious Dog193
Organization and Sequence of Human Cardiac Myosin Binding Protein C Gene (MYBPC3) and Identification of Mutations Predicted to Produce Truncated Proteins in Familial Hypertrophic Cardiomyopathy193
Effect of Exercise and Coronary Artery Narrowing on Coronary Collateral Circulation192
Measured Turbulence and Its Effect on Thrombus Formation192
Left ventricular myocardial edema. Lymph flow, interstitial fibrosis, and cardiac function.192
Change of residual strains in arteries due to hypertrophy caused by aortic constriction.192
Effect of tissue anisotropy on extracellular potential fields in canine myocardium in situ.192
Pressure drop across artificially induced stenoses in the femoral arteries of dogs.192
Effects of pH on Na+-Ca2+ exchange in canine cardiac sarcolemmal vesicles.192
Arterial Wall Mechanics in Conscious Dogs192
Functional Knockout of the Transient Outward Current, Long-QT Syndrome, and Cardiac Remodeling in Mice Expressing a Dominant-Negative Kv4 α Subunit192
Human nonmuscle myosin heavy chains are encoded by two genes located on different chromosomes.192
Increased Expression of Estrogen Receptor-β mRNA in Male Blood Vessels After Vascular Injury192
Isoproterenol antagonizes prolongation of refractory period by the class III antiarrhythmic agent E-4031 in guinea pig myocytes. Mechanism of action.192
Abnormal Ca 2+ Release, but Normal Ryanodine Receptors, in Canine and Human Heart Failure192
Adenosine Monophosphate-Activated Protein Kinase Suppresses Vascular Smooth Muscle Cell Proliferation Through the Inhibition of Cell Cycle Progression192
AMP-Activated Protein Kinase Signaling Stimulates VEGF Expression and Angiogenesis in Skeletal Muscle191
Ryanodine Receptor Mutations Associated With Stress-Induced Ventricular Tachycardia Mediate Increased Calcium Release in Stimulated Cardiomyocytes191
Tumor Necrosis Factor-α–Converting Enzyme (ADAM17) Mediates GPIbα Shedding From Platelets In Vitro and In Vivo191
Increased Superoxide Generation Is Associated With Pulmonary Hypertension in Fetal Lambs191
Impairment of Diazoxide-Induced Formation of Reactive Oxygen Species and Loss of Cardioprotection in Connexin 43 Deficient Mice191
β-Adrenergic Receptor–Stimulated Apoptosis in Cardiac Myocytes Is Mediated by Reactive Oxygen Species/c-Jun NH 2 -Terminal Kinase–Dependent Activation of the Mitocho191
Custom Design of the Cardiac Microenvironment With Biomaterials190
Functional TRPM7 Channels Accumulate at the Plasma Membrane in Response to Fluid Flow190
Effects of damaging the endocardial surface on the mechanical performance of isolated cardiac muscle.190
Effects of decreasing arterial blood pressure on cerebral blood flow in the baboon. Influence of the sympathetic nervous system.190
Restenosis After Experimental Angioplasty190
Folic Acid Reverts Dysfunction of Endothelial Nitric Oxide Synthase190
Nonbone Marrow-Derived Circulating Progenitor Cells Contribute to Postnatal Neovascularization Following Tissue Ischemia190
Role for Peroxisome Proliferator-Activated Receptor α in Oxidized Phospholipid–Induced Synthesis of Monocyte Chemotactic Protein-1 and Interleukin-8 by Endothelial Cells190
Akt Takes Center Stage in Angiogenesis Signaling189
NAD(P)H Oxidase–Dependent Self-Propagation of Hydrogen Peroxide and Vascular Disease189
The Elastic Symmetry of Arterial Segments in Dogs189
Angiotensin II Signal Transduction in Vascular Smooth Muscle189
Interactions Between Nitric Oxide and Lipid Oxidation Pathways189
A Cardiocardiac Sympathovagal Reflex in the Cat189
Activation of Distinct cAMP-Dependent and cGMP-Dependent Pathways by Nitric Oxide in Cardiac Myocytes189
Laminar Shear Stress Inhibits Vascular Endothelial Cell Proliferation by Inducing Cyclin-Dependent Kinase Inhibitor p21 Sdi1/Cip1/Waf1 189
Angiotensin II Partly Mediates Mechanical Stress–Induced Cardiac Hypertrophy189
The independent effects of oxygen radical scavengers on canine infarct size. Reduction by superoxide dismutase but not catalase.189
Increased myothermal economy of isometric force generation in compensated cardiac hypertrophy induced by pulmonary artery constriction in the rabbit. A characterization of heat liberation in normal an189
CD14+CD34 low Cells With Stem Cell Phenotypic and Functional Features Are the Major Source of Circulating Endothelial Progenitors189
Calcium Dynamics in Cortical Astrocytes and Arterioles During Neurovascular Coupling188
Epoxyeicosatrienoic Acids Activate K + Channels in Coronary Smooth Muscle Through a Guanine Nucleotide Binding Protein188
Canine Lipoproteins and Atherosclerosis188
Inhibition of Matrix Metalloproteinase Activity Inhibits Smooth Muscle Cell Migration but Not Neointimal Thickening After Arterial Injury188
Differences in the electrophysiological response of canine ventricular subendocardium and subepicardium to acetylcholine and isoproterenol. A direct effect of acetylcholine in ventricular myocardium.188
Cholinergic Atrial Fibrillation in a Computer Model of a Two-Dimensional Sheet of Canine Atrial Cells With Realistic Ionic Properties188
Angiogenic Gene Therapy for Experimental Critical Limb Ischemia188
Nitroxyl Improves Cellular Heart Function by Directly Enhancing Cardiac Sarcoplasmic Reticulum Ca 2+ Cycling188
Competition between sympathetic vasoconstriction and metabolic vasodilation in the canine coronary circulation.187
Quantitative analysis of potassium channel mRNA expression in atrial and ventricular muscle of rats.187
Ultrastructural morphometric analysis of myocardium from dogs, rats, hamsters, mice, and from human hearts.187
Relative Roles of the Sympathetic and Parasympathetic Nervous Systems in the Reflex Control of Heart Rate187
Fluid Shear Stress Activates Ca 2+ Influx Into Human Endothelial Cells via P2X4 Purinoceptors187
Cholinergically mediated tachyarrhythmias induced by a single extrastimulus in the isolated canine right atrium.187
Role of Poly-ADP Ribosyltransferase Activation in the Vascular Contractile and Energetic Failure Elicited by Exogenous and Endogenous Nitric Oxide and Peroxynitrite187
In vivo myocardial kinetics of air-filled albumin microbubbles during myocardial contrast echocardiography. Comparison with radiolabeled red blood cells.187
Endothelin and increased contractility in adult rat ventricular myocytes. Role of intracellular alkalosis induced by activation of the protein kinase C-dependent Na(+)-H+ exchanger.187
Angiogenic Role of LYVE-1–Positive Macrophages in Adipose Tissue187
Physical Activity Improves Long-Term Stroke Outcome via Endothelial Nitric Oxide Synthase–Dependent Augmentation of Neovascularization and Cerebral Blood Flow187
The Obesity-Associated Peptide Leptin Induces Hypertrophy in Neonatal Rat Ventricular Myocytes186
Intracellular pH and Tyrosine Phosphorylation but Not Calcium Determine Shear Stress–Induced Nitric Oxide Production in Native Endothelial Cells186
Relationship between blood flow to ischemic regions and extent of myocardial infarction. Serial measurement of blood flow to ischemic regions in dogs.186
Regulation of Bcl-2 Family Proteins During Development and in Response to Oxidative Stress in Cardiac Myocytes186
Action Potential Duration Restitution and Alternans in Rabbit Ventricular Myocytes186
Selectivity of Connexin-Specific Gap Junctions Does Not Correlate With Channel Conductance186
A Role for Platelets and Endothelial Selectins in Tumor Necrosis Factor-α–Induced Leukocyte Recruitment in the Brain Microvasculature186
Apoptosis Signal-Regulating Kinase 1 Plays a Pivotal Role in Angiotensin II–Induced Cardiac Hypertrophy and Remodeling186
Inhibition of Copper-Zinc Superoxide Dismutase Induces Cell Growth, Hypertrophic Phenotype, and Apoptosis in Neonatal Rat Cardiac Myocytes In Vitro186
Cardiomyocyte-Specific Overexpression of Nitric Oxide Synthase 3 Improves Left Ventricular Performance and Reduces Compensatory Hypertrophy After Myocardial Infarction186
Enhancement of Cardiac Function and Suppression of Heart Failure Progression By Inhibition of Protein Phosphatase 1186
Time course of changes in porcine myocardial phospholipid levels during ischemia. A reassessment of the lysolipid hypothesis.185
Epoxyeicosatrienoic Acids and Dihydroxyeicosatrienoic Acids Are Potent Vasodilators in the Canine Coronary Microcirculation185
Oxygen Radicals Can Induce Preconditioning in Rabbit Hearts185
Distribution of Blood (Fe 59 ) and Plasma (I 131 ) Volumes of Rats Determined by Liquid Nitrogen Freezing185
Critical Role of Endothelial Notch1 Signaling in Postnatal Angiogenesis185
Cardiac Myosin-Binding Protein-C Phosphorylation and Cardiac Function185
Excitation-contraction coupling and the ultrastructure of smooth muscle.184
Inotropic Effects of Electric Currents184
Natural Androgens Inhibit Male Atherosclerosis184
Slow Conduction and Reentry in the Ventricular Conducting System184
Ischemia and reperfusion-induced arrhythmias in the rat. Effects of xanthine oxidase inhibition with allopurinol.184
Sustained Currents Through ASIC3 Ion Channels at the Modest pH Changes That Occur During Myocardial Ischemia184
Connexin43 Is Highly Localized to Sites of Disturbed Flow in Rat Aortic Endothelium but Connexin37 and Connexin40 Are More Uniformly Distributed184
Increased Superoxide and Vascular Dysfunction in CuZnSOD-Deficient Mice184
Role of NAD(P)H Oxidase in Angiotensin II–Induced JAK/STAT Signaling and Cytokine Induction184
Interferon-gamma and tumor necrosis factor synergize to induce nitric oxide production and inhibit mitochondrial respiration in vascular smooth muscle cells.184
Angiopoietin-1 Induces Endothelial Cell Sprouting Through the Activation of Focal Adhesion Kinase and Plasmin Secretion184
Arterial Paclitaxel Distribution and Deposition183
Pharmacological Characterization of Adrenergic Alpha and Beta Receptors Mediating the Vasomotor Responses of Cerebral Arteries Ir Vitro183
Viscoelastic properties of the diastolic left ventricle in the conscious dog.183
Conduction of the Cardiac Impulse183
Effects of nifedipine on myocardial perfusion and ischemic injury in dogs.183
The selective inhibition of serotonin-induced contractions of rabbit cerebral vascular smooth muscle by calcium-antagonistic dihydropyridines. An investigation of the mechanism of action of nimodipine183
Inhibition of nitric oxide formation in the nucleus tractus solitarius increases renal sympathetic nerve activity in rabbits.183
Slow Conduction and Reentry in the Ventricular Conducting System183
Characterization and localization of endothelin receptor subtypes in the human atrioventricular conducting system and myocardium.183
Prostaglandin-Like Substances Appearing in Canine Renal Venous Blood During Renal Ischemia183
Transcapillary Escape Rate of Albumin and Plasma Volume in Essential Hypertension182
Dye Tracers Define Differential Endothelial and Smooth Muscle Coupling Patterns Within the Arteriolar Wall182
Electrophysiological and Beta-Receptor Blocking Effects of MJ 1999 on Dog and Rabbit Cardiac Tissue182
Cellular basis of chronic ventricular remodeling after myocardial infarction in rats.182
Calcitonin gene-related peptide mediates nitroglycerin and sodium nitroprusside-induced vasodilation in feline cerebral arterioles.182
Phorbol ester increases calcium current and simulates the effects of angiotensin II on cultured neonatal rat heart myocytes.182
Cardiac Sodium Channel Na v 1.5 Is Regulated by a Multiprotein Complex Composed of Syntrophins and Dystrophin182
Selective Activation of Noradrenaline and Adrenaline Producing Cells in the Cat's Adrenal Gland by Hypothalamic Stimulation181
Transgenic Overexpression of Constitutively Active Protein Kinase C ε Causes Concentric Cardiac Hypertrophy181
Adiponectin Inhibits Endothelial Synthesis of Interleukin-8181
A Ubiquitous Splice Variant and a Common Polymorphism Affect Heterologous Expression of Recombinant Human SCN5A Heart Sodium Channels181
AMP-Activated Protein Kinase Activates p38 Mitogen-Activated Protein Kinase by Increasing Recruitment of p38 MAPK to TAB1 in the Ischemic Heart181
Total and Regional Myocardial Blood Flow Measurements with 25µ, 15µ, 9µ, and Filtered 1-10µ Diameter Microspheres and Antipyrine in Dogs and Sheep181
Statins Activate Peroxisome Proliferator-Activated Receptor γ Through Extracellular Signal-Regulated Kinase 1/2 and p38 Mitogen-Activated Protein Kinase–Dependent Cyclooxygenase-2 Expression in Macrop181
IQGAP1, a Novel Vascular Endothelial Growth Factor Receptor Binding Protein, Is Involved in Reactive Oxygen Species—Dependent Endothelial Migration and Proliferation181
Platelets and Chemokines in Atherosclerosis180
Pressure-induced myogenic activation of cat cerebral arteries is dependent on intact endothelium.180
Pulmonary Arterial Pulse Wave Velocity and Impedance in Man180
Cardiotonic activity of amrinone--Win 40680 [5-amino-3,4'-bipyridine-6(1H)-one].180
Protection of human left ventricular myocardium from cutting injury with 2,3-butanedione monoxime.180
Sympathetic Innervation of the Developing Rabbit Heart180
Effect of lidocaine and quinidine on steady-state characteristics and recovery kinetics of (dV/dt)max in guinea pig ventricular myocardium.180
A Role for Endoglin in Coupling eNOS Activity and Regulating Vascular Tone Revealed in Hereditary Hemorrhagic Telangiectasia180
Matrix Metalloproteinase-9 Overexpression Enhances Vascular Smooth Muscle Cell Migration and Alters Remodeling in the Injured Rat Carotid Artery180
Isoform-Selective Activation of Protein Kinase C by Nitric Oxide in the Heart of Conscious Rabbits180
Telomere Biology and Cardiovascular Disease179
p47phox-Dependent NADPH Oxidase Regulates Flow-Induced Vascular Remodeling179
Altered Ion Transport in Vascular Smooth Muscle from Spontaneously Hypertensive Rats179
Increase in intracellular sodium ion activity during stimulation in mammalian cardiac muscle.179
Sildenafil Induces Delayed Preconditioning Through Inducible Nitric Oxide Synthase–Dependent Pathway in Mouse Heart179
Endogenous and Exogenous Nitric Oxide Inhibits Norepinephrine Release From Rat Heart Sympathetic Nerves179
QTU prolongation and polymorphic ventricular tachyarrhythmias due to bradycardia-dependent early afterdepolarizations. Afterdepolarizations and ventricular arrhythmias.179
Vasodilator-Stimulated Phosphoprotein Serine 239 Phosphorylation as a Sensitive Monitor of Defective Nitric Oxide/cGMP Signaling and Endothelial Dysfunction179
Regulation of G Protein–Coupled Receptor Signaling by Scaffold Proteins178
Vasopressin causes endothelium-dependent relaxations of the canine basilar artery.178
Dependency of Renal Blood Flow on Prostaglandin Synthesis in the Dog178
Velocity of Blood Flow in Normal Human Venae Cavae178
Efficient gene transfer into myocardium by direct injection of adenovirus vectors.178
Mast Cell–Mediated Stimulation of Angiogenesis178
Morphometric study of early postnatal development in the left and right ventricular myocardium of the rat. II. Tissue composition, capillary growth, and sarcoplasmic alterations.178
Adenovirus-Mediated Overexpression of O -GlcNAcase Improves Contractile Function in the Diabetic Heart178
Electrophysiological Effects of Diphenylhydantoin on Canine Purkinje Fibers177
Influence of lung volume on sympathetic nerve discharge in normal humans.177
A model for early afterdepolarizations: induction with the Ca2+ channel agonist Bay K 8644.177
Involvement of Rho-Kinase–Mediated Phosphorylation of Myosin Light Chain in Enhancement of Cerebral Vasospasm177
Ca 2+ -Independent Activation of the Endothelial Nitric Oxide Synthase in Response to Tyrosine Phosphatase Inhibitors and Fluid Shear Stress177
Influence of Caffeine and other Methylxanthines on Mechanical Properties of Isolated Mammalian Heart Muscle: EVIDENCE FOR A DUAL MECHANISM OF ACTION177
Luminal Ca 2+ Controls Termination and Refractory Behavior of Ca 2+ -Induced Ca 2+ Release in C177
Impact of TASK-1 in Human Pulmonary Artery Smooth Muscle Cells177
Spread of Activity Through the Atrioventricular Node176
George E. Brown memorial lecture. Role of atrial peptides in body fluid homeostasis.176
Modulation by prostaglandins of adrenergic transmission in the isolated perfused rabbit and rat kidney.176
Direct Renal Vasodilatation Produced by Dopamine in the Dog176
Defective Mitochondrial Biogenesis176
Human connexin43 gap junction channels. Regulation of unitary conductances by phosphorylation.176
Nitric Oxide–Generating Compounds Inhibit Total Protein and Collagen Synthesis in Cultured Vascular Smooth Muscle Cells176
Studies of the release from human platelets of the growth factor for cultured human arterial smooth muscle cells.176
Extracellular Superoxide Dismutase Is a Major Determinant of Nitric Oxide Bioavailability176
Genetics of Thoracic and Abdominal Aortic Diseases176
Critical Role of Monocyte Chemoattractant Protein-1 Receptor CCR2 on Monocytes in Hypertension-Induced Vascular Inflammation and Remodeling176
Compound Heterozygosity for Mutations (W156X and R225W) in SCN5A Associated With Severe Cardiac Conduction Disturbances and Degenerative Changes in the Conduction System176
Calcium-activated chloride current in rabbit ventricular myocytes.175
Action of Driving Stimuli from Intrinsic and Extrinsic Sources on in Situ Cardiac Pacemaker Tissues175
The effect of diabetes on performance and metabolism of rat hearts.175
Effects of Hypertension and Its Reversal on the Thoracic Aorta of Male and Female Rats175
Effects of acidosis and ischemia on contractility and intracellular pH of rat heart.175
Inward sodium current at resting potentials in single cardiac myocytes induced by the ischemic metabolite lysophosphatidylcholine.175
PKCζ Regulates TNF-α–Induced Activation of NADPH Oxidase in Endothelial Cells175
Exercise Training Augments Flow-Dependent Dilation in Rat Skeletal Muscle Arterioles175
Interleukin-8. A mitogen and chemoattractant for vascular smooth muscle cells.175
Low Increase in cGMP Induced by Organic Nitrates and Nitrovasodilators Improves Contractile Response of Rat Ventricular Myocytes175
20-Hydroxyeicosatetraenoic acid is an endogenous vasoconstrictor of canine renal arcuate arteries.175
Total ischemia in dog hearts, in vitro. 1. Comparison of high energy phosphate production, utilization, and depletion, and of adenine nucleotide catabolism in total ischemia in vitro vs. severe ischem175
Altered calcium handling in experimental pressure-overload hypertrophy in the ferret.174
Loss of selective endothelial cell vasoactive functions caused by hypercholesterolemia in pig coronary arteries.174
Thyroid hormone-induced alterations in phospholamban protein expression. Regulatory effects on sarcoplasmic reticulum Ca2+ transport and myocardial relaxation.174
Modulation of Cytokine-Induced Cardiac Myocyte Apoptosis by Nitric Oxide, Bak, and Bcl-x174
Effects of Levosimendan, a Cardiotonic Agent Targeted to Troponin C, on Cardiac Function and on Phosphorylation and Ca 2+ Sensitivity of Cardiac Myofibrils and Sarco174
alpha 1-adrenergic agonists precondition rabbit ischemic myocardium independent of adenosine by direct activation of protein kinase C.173
Essential Role of Smad3 in Angiotensin II–Induced Vascular Fibrosis173
Heme Is a Carbon Monoxide Receptor for Large-Conductance Ca 2+ -Activated K + Channels173
Does Ischemic Preconditioning in the Human Involve Protein Kinase C and the ATP-Dependent K + Channel?173
Pulmonary Vasoconstriction and Hypertension in Mice With Targeted Disruption of the Endothelial Nitric Oxide Synthase (NOS 3) Gene173
Retardation of Atherosclerosis by Overexpression of Catalase or Both Cu/Zn-Superoxide Dismutase and Catalase in Mice Lacking Apolipoprotein E173
Migration of cultured vascular smooth muscle cells through a basement membrane barrier requires type IV collagenase activity and is inhibited by cellular differentiation.173
Primary and Secondary Signaling Pathways in Early Preconditioning That Converge on the Mitochondria to Produce Cardioprotection173
Endothelial Cell Pathway for Conduction of Hyperpolarization and Vasodilation Along Hamster Feed Artery173
Regulation of Cardiomyocyte Apoptotic Signaling by Insulin-like Growth Factor I173
Increased blood flow inhibits neointimal hyperplasia in endothelialized vascular grafts.173
Mechanisms of NO/cGMP-Dependent Vasorelaxation173
Fluid Flow Rapidly Activates G Proteins in Human Endothelial Cells173
Pressure and Flow Generated by the Left Ventricle against Different Impedances172
The Giant Protein Titin172
Rho Kinase Mediates Cold-Induced Constriction of Cutaneous Arteries172
Hemodynamic effects of exogenous and endogenous vasopressin at low plasma concentrations in conscious dogs.172
Cyclophilin A Is Secreted by a Vesicular Pathway in Vascular Smooth Muscle Cells172
Physiological Coupling of Donor and Host Cardiomyocytes After Cellular Transplantation172
Rho and Rho Kinase Mediate Thrombin-Stimulated Vascular Smooth Muscle Cell DNA Synthesis and Migration172
Salvage of myocardial function by coronary artery reperfusion 1, 2, and 3 hours after occlusion in conscious dogs.172
Pressure Wave Transmission along the Human Aorta172
Gender Differences in Coronary Artery Diameter Involve Estrogen, Nitric Oxide, and Ca 2+ -Dependent K + Channels172
Adenoviral Expression of Vascular Endothelial Growth Factor-C Induces Lymphangiogenesis in the Skin172
Proangiogenic Action of Thyroid Hormone Is Fibroblast Growth Factor–Dependent and Is Initiated at the Cell Surface172
Restoration of Cardiac Progenitor Cells After Myocardial Infarction by Self-Proliferation and Selective Homing of Bone Marrow–Derived Stem Cells172
Reduced Gene Expression of Vascular Endothelial NO Synthase and Cyclooxygenase-1 in Heart Failure172
Derivation and Potential Applications of Human Embryonic Stem Cells171
Residual strain in rat left ventricle.171
Morphometry of the Human Pulmonary Arterial Tree171
Computer simulation of arrhythmias in a network of coupled excitable elements.171
Endothelial, not hemodynamic, differences are responsible for preferential leukocyte rolling in rat mesenteric venules.171
Brain adenosine production in the rat during 60 seconds of ischemia.171
Distribution and three-dimensional structure of intercellular junctions in canine myocardium.171
Angiotensin II Potentiates Vascular Endothelial Growth Factor–Induced Angiogenic Activity in Retinal Microcapillary Endothelial Cells171
Stimulation of Prostaglandin Biosynthesis by Adenine Nucleotides171
Time Relationship of Dynamic Events in the Cardiac Chambers, Pulmonary Artery and Aorta in Man171
Transient and Steady-State Effects of Shear Stress on Endothelial Cell Adherens Junctions171
Microsatellite Instability of Endothelial Cell Growth and Apoptosis Genes Within Plexiform Lesions in Primary Pulmonary Hypertension171
Tissue osmolality, cell swelling, and reperfusion in acute regional myocardial ischemia in the isolated porcine heart.171
Inhibition by free radical scavengers and by cyclooxygenase inhibitors of pial arteriolar abnormalities from concussive brain injury in cats.171
Blood Fibrinolytic Activity in Man171
Collateral Artery Growth (Arteriogenesis) After Experimental Arterial Occlusion Is Impaired in Mice Lacking CC-Chemokine Receptor-2171
Characterization of protein kinase C isotype expression in adult rat heart. Protein kinase C-epsilon is a major isotype present, and it is activated by phorbol esters, epinephrine, and endothelin.171
Functional Roles of Ca v 1.3 (α 1D ) Calcium Channel in Sinoatrial Nodes171
Cardiovascular aspects of human thermoregulation.170
Measurement of Viscoelastic Properties of Arteries in the Living Dog170
The Relation of Cardiac Effort to Myocardial Oxygen Consumption and Coronary Flow170
Development of the Cardiac Conduction System170
Hydrolysis of Bradykinin by Angiotensin-Converting Enzyme170
Effect of Exercise on Cardiac Output, Left Coronary Flow and Myocardial Metabolism in the Unanesthetized Dog170
Selectivity of Connexin 43 Channels Is Regulated Through Protein Kinase C–Dependent Phosphorylation170
Relation Between the Sarcolemmal Ca 2+ Current and Ca 2+ Sparks and Local Control Theories for Cardiac Excitation-Contraction Coup170
NADPH Oxidase–Derived Superoxide Anion Mediates Angiotensin II–Induced Pressor Effect via Activation of p38 Mitogen–Activated Protein Kinase in the Rostral Ventrolateral Medulla170
Cardiac-Specific Loss of N-Cadherin Leads to Alteration in Connexins With Conduction Slowing and Arrhythmogenesis170
Excitation–Transcription Coupling in Arterial Smooth Muscle169
Effect of sulfinpyrazone on homocysteine-induced endothelial injury and arteriosclerosis in baboons.169
NADPH Oxidase Activity and Function Are Profoundly Greater in Cerebral Versus Systemic Arteries169
Expression of Cyclin-Dependent Kinase Inhibitors in Vascular Disease169
Direct Demonstration of P-Selectin– and VCAM-1–Dependent Mononuclear Cell Rolling in Early Atherosclerotic Lesions of Apolipoprotein E–Deficient Mice169
Nuclear Targeting of Akt Enhances Kinase Activity and Survival of Cardiomyocytes169
Erythropoietin-Mobilized Endothelial Progenitors Enhance Reendothelialization via Akt-Endothelial Nitric Oxide Synthase Activation and Prevent Neointimal Hyperplasia169
cGMP Catabolism by Phosphodiesterase 5A Regulates Cardiac Adrenergic Stimulation by NOS3-Dependent Mechanism169
Transcoronary Transplantation of Functionally Competent BMCs Is Associated With a Decrease in Natriuretic Peptide Serum Levels and Improved Survival of Patients With Chronic Postinfarction Heart Failu169
Sympathetic Control of Coronary Circulation168
Pulmonary Vascular Impedance in the Dog168
Autonomic neural influences on the dysrhythmias resulting from myocardial infarction.168
Facilitation of adrenergic transmission by locally generated angiotensin II in rat mesenteric arteries.168
Notch Signaling in Blood Vessels168
Biology of Cardiac Arrhythmias168
ATP-sensitive potassium channel modulation of the guinea pig ventricular action potential and contraction.168
Effect of Altering Potassium Concentration on the Action of Lidocaine and Diphenylhydantoin on Rabbit Atrial and Ventricular Muscle168
Effect of preconditioning ischemia on reperfusion arrhythmias after coronary artery occlusion and reperfusion in the rat.168
Inhibition of Rho-Kinase Attenuates Hypoxia-Induced Angiogenesis in the Pulmonary Circulation168
Cyclic Strain–Induced Monocyte Chemotactic Protein-1 Gene Expression in Endothelial Cells Involves Reactive Oxygen Species Activation of Activator Protein 1168
Direct Actions of Urotensin II on the Heart168
Leukocytes are required for increased lung microvascular permeability after microembolization in sheep.167
Ventricular Fibrillation167
Effects of capsaicin and bradykinin on afferent fibers with ending in skeletal muscle.167
Unilateral Vitelline Vein Ligation Alters Intracardiac Blood Flow Patterns and Morphogenesis in the Chick Embryo167
Early Changes in Energy Metabolism in the Myocardium Following Acute Coronary Artery Occlusion in Anesthetized Dogs167
Mechanical deformation of vessel wall and shear stress determine the basal release of endothelium-derived relaxing factor in the intact rabbit coronary vascular bed.167
Role of capillary endothelium in the clearance of chylomicrons. A model for lipid transport from blood by lateral diffusion in cell membranes.167
Balloon-Artery Interactions During Stent Placement167
Recipes for Creating Animal Models of Diabetic Cardiovascular Disease167
Development of the Coronary Vessel System166
Acid-Evoked Currents in Cardiac Sensory Neurons166
Role for G 12 /G 13 in Agonist-Induced Vascular Smooth Muscle Cell Contraction166
L-arginine augments endothelium-dependent vasodilation in cholesterol-fed rabbits.166
Oxygen radicals mediate the cerebral arteriolar dilation from arachidonate and bradykinin in cats.166
Regulation of Smooth Muscle α-Actin Expression In Vivo Is Dependent on CArG Elements Within the 5′ and First Intron Promoter Regions166
Left Ventricular Wall Stress Calculated from One-Plane Cineangiography166
Alternatively Spliced IS6 Segments of the α 1C Gene Determine the Tissue-Specific Dihydropyridine Sensitivity of Cardiac and Vascular Smooth Muscle L-Type Ca 166
Control of Renin Secretion165
Neural Stimulation of Release of Renin165
Glucose and palmitate oxidation in isolated working rat hearts reperfused after a period of transient global ischemia.165
Antioxidant effects of calcium channel blockers against free radical injury in endothelial cells. Correlation of protection with preservation of glutathione levels.165
Beta 1-adrenoceptor stimulation and beta 2-adrenoceptor stimulation differ in their effects on contraction, cytosolic Ca2+, and Ca2+ current in single rat ventricular cells.165
Electrophysiological Effects of Remodeling Cardiac Gap Junctions and Cell Size165
Adverse Effects of Chronic Endogenous Sympathetic Drive Induced by Cardiac G Overexpression165
Effects of Long-Term Nitroglycerin Treatment on Endothelial Nitric Oxide Synthase (NOS III) Gene Expression, NOS III–Mediated Superoxide Production, and Vascular NO Bioavailability165
Stoichiometric Relationships Between Endothelial Tetrahydrobiopterin, Endothelial NO Synthase (eNOS) Activity, and eNOS Coupling in Vivo165
Critical Role of the NAD(P)H Oxidase Subunit p47 phox for Left Ventricular Remodeling/Dysfunction and Survival After Myocardial In165
Heart Failure and Protein Quality Control164
Reactivity of Vascular Smooth Muscle in Hypertensive Rats164
Neural Stem Cells164
Reactive dilation of large coronary arteries in conscious dogs.164
Control of Total Systemic Vascular Capacity by the Carotid Sinus Baroreceptor Reflex164
Wall Tissue Remodeling Regulates Longitudinal Tension in Arteries164
Urinary Kallikrein Excretion in Hypertensive Man164
Recruitment of an inotropic reserve in moderately ischemic myocardium at the expense of metabolic recovery. A model of short-term hibernation.164
Rotation of the Myocardial Wall of the Outflow Tract Is Implicated in the Normal Positioning of the Great Arteries164
Dissociated Spatial Patterning of Gap Junctions and Cell Adhesion Junctions During Postnatal Differentiation of Ventricular Myocardium164
Deficiency of the Cysteine Protease Cathepsin S Impairs Microvessel Growth164
Natriuretic peptides as cardiac hormones in normotensive and spontaneously hypertensive rats. The ventricle is a major site of synthesis and secretion of brain natriuretic peptide.164
Cardiac Voltage-Gated Sodium Channel Na v 1.5 Is Regulated by Nedd4-2 Mediated Ubiquitination164
Formation of Nitric Oxide–Derived Oxidants by Myeloperoxidase in Monocytes164
Receptors under pressure. An update on baroreceptors.163
Fractionation of the Cardiac Output of Rats with Isotopic Potassium163
The Molecular Basis for Distinct β-Adrenergic Receptor Subtype Actions in Cardiomyocytes163
Ca 2+ Channel Subtypes and Pharmacology in the Kidney163
Kinetics of cellular proliferation after arterial injury. IV. Heparin inhibits rat smooth muscle mitogenesis and migration.163
Neutrophil-mediated microvascular dysfunction in postischemic canine skeletal muscle. Role of granulocyte adherence.163
Connexin40 Is Essential for the Pressure Control of Renin Synthesis and Secretion163
Expression of collagen binding integrins during cardiac development and hypertrophy.163
Left Ventricular Ejection in Conscious Dogs:163
Gamma-interferon regulates vascular smooth muscle proliferation and Ia antigen expression in vivo and in vitro.163
Extracellular matrix remodeling after balloon angioplasty injury in a rabbit model of restenosis.163
Subclasses of cyclic AMP-specific phosphodiesterase in left ventricular muscle and their involvement in regulating myocardial contractility.163
Ca 2+ Scraps163
Relation between longitudinal, circumferential, and oblique shortening and torsional deformation in the left ventricle of the transplanted human heart.163
The "border zone" in myocardial ischemia. An electrophysiological, metabolic, and histochemical correlation in the pig heart.163
Vascular Smooth Muscle Updated162
Seeing Within162
Downregulation of the BK Channel β1 Subunit in Genetic Hypertension162
Two components of transient outward current in canine ventricular myocytes.162
Interstitial cells of the heart valves possess characteristics similar to smooth muscle cells.162
Altered myosin isozyme patterns from pressure-overloaded and thyrotoxic hypertrophied rabbit hearts.162
In vivo gene transfer and expression in normal uninjured blood vessels using replication-deficient recombinant adenovirus vectors.162
Supportive Interaction Between Cell Survival Signaling and Angiocompetent Factors Enhances Donor Cell Survival and Promotes Angiomyogenesis for Cardiac Repair162
Distribution of Excitation Frequencies on the Epicardial and Endocardial Surfaces of Fibrillating Ventricular Wall of the Sheep Heart162
Effect of renal hypertension and left ventricular hypertrophy on the coronary circulation in dogs.162
Cardiac Electrophysiological Actions of the Histamine H 1 -Receptor Antagonists Astemizole and Terfenadine Compared With Chlorpheniramine and Pyrilamine162
Recombinant Apolipoprotein A-I Milano Infusion Into Rabbit Carotid Artery Rapidly Removes Lipid From Fatty Streaks162
Mesenchymal Stem Cells and the Artery Wall161
Hemodynamics of the stage 12 to stage 29 chick embryo.161
Coronary arteriolar myogenic response is independent of endothelium.161
Relation Between Pressure and Diameter in the Ascending Aorta of Man161
Protein kinase C isoform expression and regulation in the developing rat heart.161
Electrophysiologic Effects of Acute Myocardial Ischemia161
Contribution of prostaglandins to the renal circulation in conscious, anesthetized, and laparotomized dogs.161
Cardiovascular and respiratory effects of adenosine in conscious man. Evidence for chemoreceptor activation.161
Recent Advances in Cardiac β 2 -Adrenergic Signal Transduction161
Dynamic ventricular interaction in the conscious dog.161
MAP Kinase Activation by Flow in Endothelial Cells161
Nitric Oxide Produced by Endothelial Cells Increases Production of Eicosanoids Through Activation of Prostaglandin H Synthase161
Persisting zones of slow impulse conduction in developing chicken hearts.161
Decreased endothelium-dependent hyperpolarization to acetylcholine in smooth muscle of the mesenteric artery of spontaneously hypertensive rats.161
[Ca 2+ ] i Inhibition of K + Channels in Canine Pulmonary Artery161
Single-Molecule Mechanics of R403Q Cardiac Myosin Isolated From the Mouse Model of Familial Hypertrophic Cardiomyopathy161
Oral Administration of Tetrahydrobiopterin Prevents Endothelial Dysfunction and Vascular Oxidative Stress in the Aortas of Insulin-Resistant Rats161
Collagen Triple Helix Repeat Containing 1, a Novel Secreted Protein in Injured and Diseased Arteries, Inhibits Collagen Expression and Promotes Cell Migration161
Viral infection and the pathogenesis of dilated cardiomyopathy.160
Titin Develops Restoring Force in Rat Cardiac Myocytes160
The Collaterals of the Coronary Arteries in Normal and Pathologic Hearts160
The effects of cardiac sympathetic nerve stimulation on perfusion of stenotic coronary arteries in the dog.160
Adenylate Kinase–Catalyzed Phosphotransfer in the Myocardium160
Multiple phenotypically distinct smooth muscle cell populations exist in the adult and developing bovine pulmonary arterial media in vivo.160
Leptin Induces Endothelin-1 in Endothelial Cells In Vitro160
Haptoglobin Genotype– and Diabetes-Dependent Differences in Iron-Mediated Oxidative Stress In Vitro and In Vivo160
Cellular Mechanisms of Aortic Aneurysm Formation160
Atrial but Not Ventricular Fibrosis in Mice Expressing a Mutant Transforming Growth Factor-β 1 Transgene in the Heart160
Inhibitors of Histone Deacetylation Downregulate the Expression of Endothelial Nitric Oxide Synthase and Compromise Endothelial Cell Function in Vasorelaxation and Angiogenesis160
Cholesterol Depletion Impairs Vascular Reactivity to Endothelin-1 by Reducing Store-Operated Ca 2+ Entry Dependent on TRPC1160
Complement Component C3 Mediates Inflammatory Injury Following Focal Cerebral Ischemia160
Effects of Propranolol on the Transmembrane Potentials of Ventricular Muscle and Purkinje Fibers of the Dog159
Sulfonylureas, ATP-sensitive K+ channels, and cellular K+ loss during hypoxia, ischemia, and metabolic inhibition in mammalian ventricle.159
Contribution of Monocytes/Macrophages to Compensatory Neovascularization159
Evidence That Late Preconditioning Against Myocardial Stunning in Conscious Rabbits Is Triggered by the Generation of Nitric Oxide159
β-Arrestin1 Knockout Mice Appear Normal but Demonstrate Altered Cardiac Responses to β-Adrenergic Stimulation159
Hypertension Management in Older and Frail Older Patients159
Spatiotemporal Heterogeneity in the Induction of Ventricular Fibrillation by Rapid Pacing159
Intravenous Allopurinol Decreases Myocardial Oxygen Consumption and Increases Mechanical Efficiency in Dogs With Pacing-Induced Heart Failure159
Activation of Inflammation and Coagulation After Infusion of C-Reactive Protein in Humans159
A reexamination of the influence of muscle length on myocardial performance.158
Myocardial infarction in rats. Infarct size, myocyte hypertrophy, and capillary growth.158
Interaction between cyclic adenosine monophosphate and cyclic gunaosine monophosphate in guinea pig ventricular myocardium.158
Angiotensin II Activates RhoA in Cardiac Myocytes158
Effects of partial neuromuscular blockade on sympathetic nerve responses to static exercise in humans.158
Stimulation of renin release from rabbit renal cortex by arachidonic acid and prostaglandin endoperoxides.158
Frequency-Dependent Breakdown of Wave Propagation Into Fibrillatory Conduction Across the Pectinate Muscle Network in the Isolated Sheep Right Atrium158
Troponin I gene expression during human cardiac development and in end-stage heart failure.158
Prevention and Reversal of Premature Endothelial Cell Senescence and Vasculopathy in Obesity-Induced Diabetes by Ebselen158
Upregulated TRPC1 Channel in Vascular Injury In Vivo and Its Role in Human Neointimal Hyperplasia158
Response of Small Pulmonary Arteries to Unilobar Hypoxia and Hypercapnia157
Left Ventricular Dimensions Recorded by Sonocardiometry157
Pathogenesis of acute renal failure following temporary renal ischemia in the rat.157
Hydraulic Power Associated with Pulmonary Blood Flow and its Relation to Heart Rate157
Measurement of Renin Activity in Human Plasma157
Small Amounts of α-Myosin Heavy Chain Isoform Expression Significantly Increase Power Output of Rat Cardiac Myocyte Fragments157
The dependence of ultrasonic attenuation and backscatter on collagen content in dog and rabbit hearts.157
Slow Conduction in Cardiac Tissue, I157
In Vivo Echocardiographic Detection of Enhanced Left Ventricular Function in Gene-Targeted Mice With Phospholamban Deficiency157
Sustained Increase in Aortic Endothelial Nitric Oxide Synthase Expression In Vivo in a Model of Chronic High Blood Flow157
Effects of Chronic Excess Salt Ingestion157
Differential Expression of Voltage-Gated K + Channel Subunits in Adult Rat Heart157
Prevention of Hypoxia-Induced Pulmonary Hypertension by Enhancement of Endogenous Heme Oxygenase-1 in the Rat157
Role of the Calcium-Independent Transient Outward Current I to1 in Shaping Action Potential Morphology and Duration157
Differential effects of transforming growth factor-beta 1 and phorbol myristate acetate on cardiac fibroblasts. Regulation of fibrillar collagen mRNAs and expression of early transcription factors.157
Molecular Basis of Human Cardiac Troponin T Isoforms Expressed in the Developing, Adult, and Failing Heart157
Caveolin-1 Expression Is Critical for Vascular Endothelial Growth Factor–Induced Ischemic Hindlimb Collateralization and Nitric Oxide–Mediated Angiogenesis157
Ca 2+ Influx–Induced Sarcoplasmic Reticulum Ca 2+ Overload Causes Mitochondrial-Dependent Apoptosis in Ventricular Myocytes157
Role of Soluble Epoxide Hydrolase in Postischemic Recovery of Heart Contractile Function157
Electrogenic Suppression of Automaticity in Sheep and Dog Purkinje Fibers156
Determinants of Duration and Mean Rate of Ventricular Ejection156
Collagen and Elastin Content in Canine Arteries Selected from Functionally Different Vascular Beds156
Alpha 1-adrenoceptor-mediated phosphoinositide breakdown and inotropic response in rat left ventricular papillary muscles.156
Connexin 43 Downregulation and Dephosphorylation in Nonischemic Heart Failure Is Associated With Enhanced Colocalized Protein Phosphatase Type 2A156
Impairment of autonomically mediated heart rate control in patients with cardiac dysfunction.156
Rho Kinase–Induced Nuclear Translocation of ERK1/ERK2 in Smooth Muscle Cell Mitogenesis Caused by Serotonin156
N-acetylcysteine potentiates platelet inhibition by endothelium-derived relaxing factor.156
Interactions of vasopressin with the area postrema in arterial baroreflex function in conscious rabbits.156
Hemodynamics Is a Key Epigenetic Factor in Development of the Cardiac Conduction System156
Calmodulin Is Essential for Cardiac I KS Channel Gating and Assembly156
Statins Protect Human Aortic Smooth Muscle Cells From Inorganic Phosphate-Induced Calcification by Restoring Gas6-Axl Survival Pathway156
Abnormal Interactions of Calsequestrin With the Ryanodine Receptor Calcium Release Channel Complex Linked to Exercise-Induced Sudden Cardiac Death156
Reentrant and nonreentrant mechanisms contribute to arrhythmogenesis during early myocardial ischemia: results using three-dimensional mapping.155
Mechanical Transduction of Nitric Oxide Synthesis in the Beating Heart155
Transgenic Expression of Bcl-2 Modulates Energy Metabolism, Prevents Cytosolic Acidification During Ischemia, and Reduces Ischemia/Reperfusion Injury155
Effects of Autonomic Blockade on the Baroreflex in Man at Rest and During Exercise155
Changes in brain adenosine during bicuculline-induced seizures in rats. Effects of hypoxia and altered systemic blood pressure.155
Transient Receptor Potential Melastatin 7 Ion Channels Regulate Magnesium Homeostasis in Vascular Smooth Muscle Cells155
Passive properties of canine left ventricle: diastolic stiffness and restoring forces.155
Increasing Ryanodine Receptor Open Probability Alone Does Not Produce Arrhythmogenic Calcium Waves155
Selective accumulation of the first component of complement and leukocytes in ischemic canine heart muscle. A possible initiator of an extra myocardial mechanism of ischemic injury.155
Angiotensin II Impairs the Insulin Signaling Pathway Promoting Production of Nitric Oxide by Inducing Phosphorylation of Insulin Receptor Substrate-1 on Ser 312 and 155
Possible Involvement of Stress-Activated Protein Kinase Signaling Pathway and Fas Receptor Expression in Prevention of Ischemia/Reperfusion-Induced Cardiomyocyte Apoptosis by Carvedilol155
Hypertension Caused by Salt Loading in the Dog154
Transmural Heterogeneity of Calcium Handling in Canine154
Cardiac myosin heavy chain mRNA expression and myocardial function in the mouse heart.154
Relationship between blood flow direction and endothelial cell orientation at arterial branch sites in rabbits and mice.154
Stability of heterogeneity of myocardial blood flow in normal awake baboons.154
Developmental Changes in the Delayed Rectifier K + Channels in Mouse Heart154
Failure of atriopeptin II to cause arterial vasodilation in the conscious rat.154
Hydrogen peroxide and hydroxyl radical mediation of activated leukocyte depression of cardiac sarcoplasmic reticulum. Participation of the cyclooxygenase pathway.154
Oxidative Stress–Dependent Sphingosine Kinase-1 Inhibition Mediates Monoamine Oxidase A–Associated Cardiac Cell Apoptosis154
Role of Endothelium-Derived Nitric Oxide in the Modulation of Canine Myocardial Mitochondrial Respiration In Vitro154
The Range of Adaptation by Collateral Vessels After Femoral Artery Occlusion154
14,15-Epoxyeicosa-5( Z )-enoic Acid154
Electrogenesis of increased norepinephrine sensitivity of arterial vascular muscle in hypertension.153
Myoplasmic [Ca2+] determines myosin phosphorylation in agonist-stimulated swine arterial smooth muscle.153
Block of inactivated sodium channels and of depolarization-induced automaticity in guinea pig papillary muscle by amiodarone.153
Effect of alteration of left ventricular activation sequence on the left ventricular end-systolic pressure-volume relation in closed-chest dogs.153
The failing human heart is unable to use the Frank-Starling mechanism.153
Epicardial Outgrowth Inhibition Leads to Compensatory Mesothelial Outflow Tract Collar and Abnormal Cardiac Septation and Coronary Formation153
Inhaled nitric oxide reverses pulmonary vasoconstriction in the hypoxic and acidotic newborn lamb.153
Characterization of a Novel PKA Phosphorylation Site, Serine-2030, Reveals No PKA Hyperphosphorylation of the Cardiac Ryanodine Receptor in Canine Heart Failure153
Fluid Shear Stress Transcriptionally Induces Lectin-like Oxidized LDL Receptor-1 in Vascular Endothelial Cells152
Measurement of Umbilical Arterial Blood Flow to the Sheep Placenta and Fetus in Utero152
Myoendothelial Differentiation of Human Umbilical Cord Blood–Derived Stem Cells in Ischemic Limb Tissues152
Sustained β 1 -Adrenergic Stimulation Modulates Cardiac Contractility by Ca 2+ /Calmodulin Kinase Signaling Pathway152
Targeted Overexpression of the Sarcoplasmic Reticulum Ca 2+ -ATPase Increases Cardiac Contractility in Transgenic Mouse Hearts152
Malonyl Coenzyme A Decarboxylase Inhibition Protects the Ischemic Heart by Inhibiting Fatty Acid Oxidation and Stimulating Glucose Oxidation152
Preferential Expression and Function of Voltage-Gated, O 2 -Sensitive K + Channels in Resistance Pulmonary Arteries Explains Regio152
Telomeres and Cardiovascular Disease152
Effect of maximal coronary vasodilation on transmural myocardial perfusion during tachycardia in the awake dog.152
Excitation-contraction coupling in postischemic myocardium. Does failure of activator Ca2+ transients underlie stunning?152
IP-10 Blocks Vascular Endothelial Growth Factor-Induced Endothelial Cell Motility and Tube Formation via Inhibition of Calpain152
Cytokine-Mediated Apoptosis in Cardiac Myocytes152
Calcineurin and Beyond151
Metabolism of adenine nucleotides in human blood.151
Coronary diastolic pressure-flow relation and zero flow pressure explained on the basis of intramyocardial compliance.151
Cyclooxygenase-1 Participates in Selected Vasodilator Responses of the Cerebral Circulation151
Excitation-Contraction Coupling of Isolated Cardiac Fibers with Disrupted or Closed Sarcolemmas: CALCIUM-DEPENDENT CYCLIC AND TONIC CONTRACTIONS151
Overexpression of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Induces Intramyocardial Vasculopathy in Apolipoprotein E–Null Mice151
The role of autoregulation and tissue diastolic pressures in the transmural distribution of left ventricular blood flow in anesthetized dogs.151
Nitric Oxide Promotes Proliferation and Plasminogen Activator Production by Coronary Venular Endothelium Through Endogenous bFGF151
Ventricular activation patterns of spontaneous and induced ventricular rhythms in canine one-day-old myocardial infarction. Evidence for focal and reentrant mechanisms.151
Breakdown and Release of Myofilament Proteins During Ischemia and Ischemia/Reperfusion in Rat Hearts151
Thrombospondin-2 Is Essential for Myocardial Matrix Integrity151
Effect of Hematocrit on Venous Return150
Blood Flow in Cutaneous Tissue in Man Studied by Washout of Radioactive Xenon150
Gestational changes in pulmonary vascular responses in fetal lambs in utero.150
Brugada Syndrome150
Regional Myocardial Blood Flow in Lambs with Concentric Right Ventricular Hypertrophy150
Atrial reentry around an anatomic barrier with a partially refractory excitable gap. A canine model of atrial flutter.150
α v β 3 Integrin Expression in Normal and Atherosclerotic Artery150
Expression of A-, B-, and C-type natriuretic peptide genes in failing and developing human ventricles. Correlation with expression of the Ca(2+)-ATPase gene.150
Mechanism of Action of Epinephrine and Glucagon on the Canine Heart: EVIDENCE FOR INCREASE IN SARCOTUBULAR CALCIUM STORES MEDIATED BY CYCLIC 3',5'-AMP150
Preservation of endothelium-dependent vascular relaxation in cholesterol-fed rabbit by treatment with the calcium blocker PN 200110.150
Evidence of Structural Remodeling in the Dyssynchronous Failing Heart150
The economy of isometric force development, myosin isoenzyme pattern and myofibrillar ATPase activity in normal and hypothyroid rat myocardium.150
Phospholemman-Phosphorylation Mediates the β-Adrenergic Effects on Na/K Pump Function in Cardiac Myocytes150
Pulmonary Blood Flow and Venous Return During Spontaneous Respiration149
Contractures and increase in internal longitudianl resistance of cow ventricular muscle induced by hypoxia.149
Improvement of Endothelial Function by Systemic Transfusion of Vascular Progenitor Cells149
Downregulation of Soluble Guanylyl Cyclase in Young and Aging Spontaneously Hypertensive Rats149
Effects of tetrodotoxin, lidocaine, verapamil, and AHR-2666 on Ouabain-induced delayed afterdepolarizations in canine Purkinje fibers.149
Rat angiotensin II (type 1A) receptor mRNA regulation and subtype expression in myocardial growth and hypertrophy.149
Developmentally Regulated Switching of Titin Size Alters Myofibrillar Stiffness in the Perinatal Heart149
Interaction of verapamil and other calcium channel blockers with alpha 1- and alpha 2-adrenergic receptors.149
An analysis of the mechanical disadvantage of myocardial infarction in the canine left ventricle.149
Velocity distribution and intimal proliferation in autologous vein grafts in dogs.149
Neuronal Nitric Oxide Synthase Is Expressed in Rat Vascular Smooth Muscle Cells149
Urinary Kallikrein Excretion in Normal Man149
Preferential distribution of inhibitory cardiac receptors with vagal afferents to the inferoposterior wall of the left ventricle activated during coronary occlusion in the dog.149
A Proinflammatory Gut Microbiota Increases Systemic Inflammation and Accelerates Atherosclerosis149
Heart size.148
Pericardial and Ventricular Pressure148
Is Depressed Myocyte Contractility Centrally Involved in Heart Failure?148
Mechanism of augmented rate of left ventricular filling during exercise.148
Prolonged impairment of coronary vasodilation after reversible ischemia. Evidence for microvascular "stunning".148
Reduction by Propranolol of Myocardial Necrosis following Temporary Coronary Artery Occlusion in Dogs148
Hypothermic arrest and potassium arrest: metabolic and myocardial protection during elective cardiac arrest.148
Characteristics of transient outward current in human ventricular myocytes from patients with terminal heart failure.148
Contraction-Induced Cell Wounding and Release of Fibroblast Growth Factor in Heart148
cAMP-Binding Protein Epac Induces Cardiomyocyte Hypertrophy148
Diastolic Geometry and Sarcomere Lengths in the Chronically Dilated Canine Left Ventricle148
Effect of Intra-arterial Insulin on Tissue Cholesterol and Fatty Acids in Alloxan-Diabetic Dogs148
Hormonal and cardiac effects of converting enzyme inhibition in rat myocardial infarction.148
Enhanced Basal Activity of a Cardiac Ca 2+ Release Channel (Ryanodine Receptor) Mutant Associated With Ventricular Tachycardia and Sudden Death148
Functional and Biochemical Analysis of Angiotensin II–Forming Pathways in the Human Heart148
Mechanism of cytokine inhibition of beta-adrenergic agonist stimulation of cyclic AMP in rat cardiac myocytes. Impairment of signal transduction.148
Acetyl glyceryl ether phosphorylcholine (AGEPC). A putative mediator of cardiac anaphylaxis in the guinea pig.148
Cardiotrophic Effects of Protein Kinase C ε148
Myosin Binding Protein C, a Phosphorylation-Dependent Force Regulator in Muscle That Controls the Attachment of Myosin Heads by Its Interaction With Myosin S2148
Acute alterations in left ventricular diastolic chamber stiffness. Role of the "erectile" effect of coronary arterial pressure and flow in normal and damaged hearts.148
Phospholipid alterations in canine ischemic myocardium. Temporal and topographical correlations with Tc-99m-PPi accumulation and an in vitro sarcolemmal Ca2+ permeability defect.148
Calcineurin-Mediated Hypertrophy Protects Cardiomyocytes From Apoptosis In Vitro and In Vivo148
Increased Sarcoplasmic Reticulum Calcium Leak but Unaltered Contractility by Acute CaMKII Overexpression in Isolated Rabbit Cardiac Myocytes148
Endothelial Progenitor Thrombospondin-1 Mediates Diabetes-Induced Delay in Reendothelialization Following Arterial Injury148
Reprogramming of the Human Atrial Transcriptome in Permanent Atrial Fibrillation148
Cardiac Intracellular Calcium Release Channels147
Capillary Exchange Modeling147
Ventricular intramural and epicardial potential distributions during ventricular activation and repolarization in the intact dog.147
Mechanotransduction of Rat Aortic Vascular Smooth Muscle Cells Requires RhoA and Intact Actin Filaments147
Mechanisms of action of lidocaine and quinidine on action potential duration in rabbit cardiac Purkinje fibers. An effect on steady state sodium currents?147
Electrophysiological Characterization of an Alternatively Processed ERG K + Channel in Mouse and Human Hearts147
Reduction of ischemic K+ loss and arrhythmias in rat hearts. Effect of glibenclamide, a sulfonylurea.147
Focal Adhesion Kinase Is Activated and Mediates the Early Hypertrophic Response to Stretch in Cardiac Myocytes147
The renal sympathetic baroreflex in the rabbit. Arterial and cardiac baroreceptor influences, resetting, and effect of anesthesia.147
Muscle Ring Finger 1, but not Muscle Ring Finger 2, Regulates Cardiac Hypertrophy In Vivo147
Mineralocorticoid Receptor Blocker Increases Angiotensin-Converting Enzyme 2 Activity in Congestive Heart Failure Patients147
Multifunctional Ca2+/calmodulin-dependent protein kinase mediates Ca(2+)-induced enhancement of the L-type Ca2+ current in rabbit ventricular myocytes.147
Vangl2 Acts via RhoA Signaling to Regulate Polarized Cell Movements During Development of the Proximal Outflow Tract147
Potassium accumulation in the globally ischemic mammalian heart. A role for the ATP-sensitive potassium channel.147
Shear Stress Induces ATP-Independent Transient Nitric Oxide Release From Vascular Endothelial Cells, Measured Directly With a Porphyrinic Microsensor147
L-type Voltage-Gated Ca 2+ Channels Modulate Expression of Smooth Muscle Differentiation Marker Genes via a Rho Kinase/Myocardin/SRF–Dependent Mechanism147
Nitric Oxide Regulation of Myocardial Contractility and Calcium Cycling147
Myocardial Dysfunction With Coronary Microembolization147
Serotonin Inhibits Voltage-Gated K + Currents in Pulmonary Artery Smooth Muscle Cells147
Overexpression of Human Catalase Inhibits Proliferation and Promotes Apoptosis in Vascular Smooth Muscle Cells147
Insulin-Like Growth Factor-1 Enhances Inflammatory Responses in Endothelial Cells147
Mechanism of Hydrocortisone Potentiation of Responses to Epinephrine and Norepinephrine in Rabbit Aorta146
Influence of Deformability of Human Red Cells upon Blood Viscosity146
Fluid dynamics of coronary artery stenosis.146
Inhibition of sympathetic neurotransmission in canine blood vessels by adenosine and adenine nucleotides.146
Endothelium-Derived Hyperpolarizing Factors and Vascular Cytochrome P450 Metabolites of Arachidonic Acid in the Regulation of Tone146
Circulating Progenitor Cells Regenerate Endothelium of Vein Graft Atherosclerosis, Which Is Diminished in ApoE-Deficient Mice146
Cardiac Efficiency Is Improved After Ischemia by Altering Both the Source and Fate of Protons146
Mixed Messages146
Two-Pore Domain K Channel, TASK-1, in Pulmonary Artery Smooth Muscle Cells146
Tachycardia-Induced Changes in Na + Current in a Chronic Dog Model of Atrial Fibrillation146
Changes in substrate metabolism and effects of excess fatty acids in reperfused myocardium.146
Molecular and Functional Signature of Heart Hypertrophy During Pregnancy146
Suppression of plasma renin activity by indomethacin in man.146
Effect of Verapamil on the Normal Action Potential and on a Calcium Dependent Slow Response of Canine Cardiac Purkinje Fibers146
Serotonin-Induced Smooth Muscle Hyperplasia in Various Forms of Human Pulmonary Hypertension146
Reentrant ventricular arrhythmias in the late myocardial infarction period in the dog. 13. Correlation of activation and refractory maps.146
Myozenin 2 Is a Novel Gene for Human Hypertrophic Cardiomyopathy146
Epigenetic Histone Modification and Cardiovascular Lineage Programming in Mouse Embryonic Stem Cells Exposed to Laminar Shear Stress146
Anticytokine Agents146
Transgenic Mice Overexpressing the 5-Hydroxytryptamine Transporter Gene in Smooth Muscle Develop Pulmonary Hypertension146
A Specific Pattern of Phosphodiesterases Controls the cAMP Signals Generated by Different G s -Coupled Receptors in Adult Rat Ventricular Myocytes146
Potentiation of endothelium-dependent relaxations to bradykinin by angiotensin I converting enzyme inhibitors in canine coronary artery involves both endothelium-derived relaxing and hyperpolarizing f146
Mechanism of adenosine inhibition of catecholamine-induced responses in heart.145
Dependence of Wall Stress in the Human Thoracic Aorta on Age and Pressure145
Physiology of Canine Intraventricular Conduction and Endocardial Excitation145
Cardiac myocytes express multiple gap junction proteins.145
Factors Controlling Pacemaker Action in Cells of the Sinoatrial Node145
Transforming Growth Factor-β-Induced Differentiation of Smooth Muscle From a Neural Crest Stem Cell Line145
Angiopoietin-1 Promotes Cardiac and Skeletal Myocyte Survival Through Integrins145
Role of Adenine Nucleotides, Adenosine, and Inorganic Phosphate in the Regulation of Skeletal Muscle Blood Flow145
Nod1-Mediated Endothelial Cell Activation by Chlamydophila pneumoniae145
Mechanical Strain Increases Smooth Muscle and Decreases Nonmuscle Myosin Expression in Rat Vascular Smooth Muscle Cells145
High Glucose Concentrations Increase Endothelial Cell Permeability via Activation of Protein Kinase Cα145
Expression of sarcoplasmic reticulum Ca(2+)-ATPase and calsequestrin genes in rat heart during ontogenic development and aging.145
Cellular origins of the transient inward current in cardiac myocytes. Role of fluctuations and waves of elevated intracellular calcium.145
Matrix Metalloproteinase-9 Is Required for Adequate Angiogenic Revascularization of Ischemic Tissues145
Anti–Monocyte Chemoattractant Protein-1/Monocyte Chemotactic and Activating Factor Antibody Inhibits Neointimal Hyperplasia in Injured Rat Carotid Arteries145
Rapid Endothelial Cell–Selective Loading of Connexin 40 Antibody Blocks Endothelium-Derived Hyperpolarizing Factor Dilation in Rat Small Mesenteric Arteries145
Increases in Mitochondrial Reactive Oxygen Species Trigger Hypoxia-Induced Calcium Responses in Pulmonary Artery Smooth Muscle Cells145
Comparison of the effects of regional ischemia, hypoxia, hyperkalemia, and acidosis on intracellular and extracellular potentials and metabolism in the isolated porcine heart.145
Adherent Platelets Recruit and Induce Differentiation of Murine Embryonic Endothelial Progenitor Cells to Mature Endothelial Cells In Vitro145
Critical Roles of Muscle-Secreted Angiogenic Factors in Therapeutic Neovascularization145
Mechanosensitive gating of atrial ATP-sensitive potassium channels.144
Cardiac Actions of Glucagon144
Changes in Content of Purine Nucleoside in Canine Myocardium during Coronary Occlusion144
Triggered and automatic activity in the canine coronary sinus.144
Responsiveness of Isolated Cerebral and Peripheral Arteries to Serotonin, Norepinephrine, and Transmural Electrical Stimulation144
Effect of arterial impedance changes on the end-systolic pressure-volume relation.144
Step Hypocapnia to Separate Arterial from Tissue Pco 2 in the Regulation of Cerebral Blood Flow144
Daunorubicin-Induced Apoptosis in Rat Cardiac Myocytes Is Inhibited by Dexrazoxane144
Rapid Displacement of Vimentin Intermediate Filaments in Living Endothelial Cells Exposed to Flow144
Rat carotid neointimal smooth muscle cells reexpress a developmentally regulated mRNA phenotype during repair of arterial injury.144
Rapamycin Selectively Inhibits Angiotensin II–Induced Increase in Protein Synthesis in Cardiac Myocytes In Vitro144
Activation of Sphingosine Kinase-1 Reverses the Increase in Lung Vascular Permeability Through Sphingosine-1-Phosphate Receptor Signaling in Endothelial Cells144
Distribution and Functional Characterization of Equilibrative Nucleoside Transporter-4, a Novel Cardiac Adenosine Transporter Activated at Acidic pH144
Prostaglandins mediate arteriolar dilation to increased blood flow velocity in skeletal muscle microcirculation.143
Effect of Calcium on Acetylstrophanthidin-Induced Transient Depolarizations in Canine Purkinje Tissue143
Effects of gonadectomy and hormonal replacement on rat hearts.143
Duration of the Phases of Left Ventricular Systole143
Renomedullary Vasodepressor Substance, Medullin143
Expression of cellular oncogenes in the myocardium during the developmental stage and pressure-overloaded hypertrophy of the rat heart.143
Effects of Action Potential Duration on Excitation-Contraction Coupling in Rat Ventricular Myocytes143
Protracted ventricular tachcardia induced by premature stimulation of the canine heart after coronary artery occlusion and reperfusion.143
Continuous positive-pressure ventilation decreases right and left ventricular end-diastolic volumes in the dog.143
Alterations of Na + Currents in Myocytes From Epicardial Border Zone of the Infarcted Heart143
Potential Molecular Basis of Different Physiological Properties of the Transient Outward K + Current in Rabbit and Human Atrial Myocytes143
Circus Movement within the AV Node as a Basis for Supraventricular Tachycardia as Shown by Multiple Microelectrode Recording in the Isolated Rabbit Heart143
Impaired Long-Chain Fatty Acid Utilization by Cardiac Myocytes Isolated From Mice Lacking the Heart-Type Fatty Acid Binding Protein Gene143
Angiotensin II Type 2 Receptor Is Upregulated in Human Heart With Interstitial Fibrosis, and Cardiac Fibroblasts Are the Major Cell Type for Its Expression143
Electrophysiological Properties of the Canine Peripheral A-V Conducting System142
The effect of streptozotocin-induced diabetes in rats on cardiac contractile proteins.142
Smooth Muscle α-Actin Is a Direct Target of Notch/CSL142
Gap Junction Communication Mediates Transforming Growth Factor-β Activation and Endothelial-Induced Mural Cell Differentiation142
The myocardial cell surface, its histochemistry, and the effect of sialic acid and calcium removal on its stucture and cellular ionic exchange.142
cGMP and Nitric Oxide Modulate Thrombin-Induced Endothelial Permeability142
Beneficial Effects of Trimetazidine in Ex Vivo Working Ischemic Hearts Are Due to a Stimulation of Glucose Oxidation Secondary to Inhibition of Long-Chain 3-Ketoacyl Coenzyme A Thiolase142
Oxidized Low-Density Lipoprotein–Dependent Endothelial Arginase II Activation Contributes to Impaired Nitric Oxide Signaling142
Requirement for Rac1-Dependent NADPH Oxidase in the Cardiovascular and Dipsogenic Actions of Angiotensin II in the Brain142
Angiotensin II Type 1 Receptor–Induced Extracellular Signal–Regulated Protein Kinase Activation Is Mediated by Ca 2+ /Calmodulin-Dependent Transactivation of Epiderm142
Angiotensin AT 1 and AT 2 Receptors Differentially Regulate Angiopoietin-2 and Vascular Endothelial Growth Factor Expression and A142
A Computer Model of Normal Conduction in the Human Atria141
Developmental and hormonal regulation of sarcomeric myosin heavy chain gene family.141
Effect of Ischemia on Adenine Nucleotides in Cardiac and Skeletal Muscle141
Patterned growth of neonatal rat heart cells in culture. Morphological and electrophysiological characterization.141
Localization of angiotensin converting enzyme in rat heart.141
Intestinal vasodilation by epoxyeicosatrienoic acids: arachidonic acid metabolites produced by a cytochrome P450 monooxygenase.141
Developmental Changes in Ionic Channel Activity in the Embryonic Murine Heart141
Connexin45 Expression Is Preferentially Associated With the Ventricular Conduction System in Mouse and Rat Heart141
Role of angiotensin II in the altered renal function of congestive heart failure.141
Phorbol ester increases the dihydropyridine-sensitive calcium conductance in a vascular smooth muscle cell line.141
Regulation of fibrillar collagen types I and III and basement membrane type IV collagen gene expression in pressure overloaded rat myocardium.141
Pharmacologically Preconditioned Skeletal Myoblasts Are Resistant to Oxidative Stress and Promote Angiomyogenesis via Release of Paracrine Factors in the Infarcted Heart141
Regulation of Vascular Endothelial Growth Factor in Cardiac Myocytes141
Essential Role of ICAM-1/CD18 in Mediating EPC Recruitment, Angiogenesis, and Repair to the Infarcted Myocardium141
Inhibition of p38 MAPK Activation via Induction of MKP-1141
Importance of Monocyte Chemoattractant Protein-1 Pathway in Neointimal Hyperplasia After Periarterial Injury in Mice and Monkeys141
Nitrolinoleate Inhibits Superoxide Generation, Degranulation, and Integrin Expression by Human Neutrophils141
Conformation-Specific Blockade of the Integrin GPIIb/IIIa141
Exacerbation of Cerebral Injury in Mice That Express the P-Selectin Gene141
Cardiac Physiology in Transgenic Mice140
Single cardiac vagal fiber activity, acute myocardial ischemia, and risk for sudden death.140
Contribution of endogenous endothelin to the extension of myocardial infarct size in rats.140
Influence of Extracellular K + Concentration on Cable Properties and Excitability of Sheep Cardiac Purkinje Fibers140
The effects of verapamil, quiescence, and cardioplegia on calcium exchange and mechanical function in ischemic rabbit myocardium.140
Morphometric study of early postnatal development in the left and right ventricular myocardium of the rat. I. Hypertrophy, hyperplasia, and binucleation of myocytes.140
External detection and visualization of myocardial ischemia with 11C-substrates in vitro and in vivo.140
Increased Atherosclerosis in Mice Lacking Apolipoprotein A-I Attributable to Both Impaired Reverse Cholesterol Transport and Increased Inflammation140
Inhibition of Na + -H + Exchange Prevents Hypertrophy, Fibrosis, and Heart Failure in β 1 -Adre140
Pre–B-Cell Colony–Enhancing Factor Regulates NAD + -Dependent Protein Deacetylase Activity and Promotes Vascular Smooth Muscle Cell Maturation140
Regulation of Cardiac Ca 2+ Release Channel (Ryanodine Receptor) by Ca 2+ , H + , Mg 140
Protective effect of increased glycolytic substrate against systolic and diastolic dysfunction and increased coronary resistance from prolonged global underperfusion and reperfusion in isolated rabbit140
Morphometry of the small pulmonary arteries in man.139
Vascular Impedance of the Femoral Bed139
G Protein–Coupled Receptor Oligomerization139
Phasic coronary blood flow velocity in intramural and epicardial coronary arteries.139
Hypoxia/Reoxygenation Stimulates Jun Kinase Activity Through Redox Signaling in Cardiac Myocytes139
Diminished endothelium-derived relaxing factor activity in an experimental model of chronic heart failure.139
Ventricular arrhythmias and electrophysiological consequences of myocardial ischemia and infarction.139
Mechanical Stretch and Angiotensin II Differentially Upregulate the Renin-Angiotensin System in Cardiac Myocytes In Vitro139
Effect of vagal stimulation on the overflow of norepinephrine into the coronary sinus during cardiac sympathetic nerve stimulation in the dog.139
Agonist-Induced Activation of Matrix Metalloproteinase-7 Promotes Vasoconstriction Through the Epidermal Growth Factor–Receptor Pathway139
Activation of Mitochondrial ATP-Sensitive K + Channel for Cardiac Protection Against Ischemic Injury Is Dependent on Protein Kinase C Activity139
Iloprost inhibits neutrophil function in vitro and in vivo and limits experimental infarct size in canine heart.139
Role of Sodium-Calcium Exchanger in Modulating the Action Potential of Ventricular Myocytes From Normal and Failing Hearts139
Thrombogenic Effects of Antiphospholipid Antibodies Are Mediated by Intercellular Cell Adhesion Molecule-1, Vascular Cell Adhesion Molecule-1, and P-Selectin139
Induction of Serotonin Transporter by Hypoxia in Pulmonary Vascular Smooth Muscle Cells139
Antiangiogenic Effect of Interleukin-10 in Ischemia-Induced Angiogenesis in Mice Hindlimb139
Exercise Can Prevent and Reverse the Severity of Hypertrophic Cardiomyopathy139
Functional Roles of Cardiac and Vascular ATP-Sensitive Potassium Channels Clarified by Kir6.2-Knockout Mice139
Quantification of [Ca2+]i in perfused hearts. Critical evaluation of the 5F-BAPTA and nuclear magnetic resonance method as applied to the study of ischemia and reperfusion.139
Spread of Excitation from the Sinus Node138
Regulation of adenosine formation by the heart.138
Mechanisms of Cardiac Control in Exercise138
Alterations in cardiac sarcoplasmic reticulum calcium transport in the postischemic "stunned" myocardium.138
On the Mechanism of Vascular Leakage Caused by Histamine-Type Mediators138
What Sets the Long-Term Level of Renal Sympathetic Nerve Activity138
Association of Human Connexin40 Gene Polymorphisms With Atrial Vulnerability as a Risk Factor for Idiopathic Atrial Fibrillation138
Mapping the Murine Cardiac 26S Proteasome Complexes138
Mechanisms Underlying the Increase in Force and Ca 2+ Transient That Follow Stretch of Cardiac Muscle138
Recovery of left ventricular segmental function after long-term reperfusion following temporary coronary occlusion in conscious dogs. Comparison of 2- and 4-hour occlusions.138
The blood-brain barrier. Transport across the cerebral endothelium.137
Metabolic responses to cardiac hypoxia. Increased production of succinate by rabbit papillary muscles.137
Coronary collateral development in swine after coronary artery occlusion.137
High-Density Lipoprotein Regulates Calcification of Vascular Cells137
Regulation of total and regional spinal cord blood flow.137
Covalent and Noncovalent Modification of Thin Filament Action137
Glutathiolation Regulates Tumor Necrosis Factor-α–Induced Caspase-3 Cleavage and Apoptosis137
Evidence for hyperplasia in mesenteric resistance vessels of spontaneously hypertensive rats using a three-dimensional disector.137
Possible mechanisms of ventricular arrhythmias elicited by ischemia followed by reperfusion. Studies on isolated canine ventricular tissues.137
Further Observations on the Activation and Inhibition of Lipoprotein Lipase by Apolipoproteins137
Extracellular Potentials Related to Intracellular Action Potentials in the Dog Purkinje System137
Functional Proteomic Analysis of Protein Kinase C ε Signaling Complexes in the Normal Heart and During Cardioprotection137
Echocardiographic Assessment of Left Ventricular Mass and Systolic Function in Mice137
Remodeling of Gap Junctional Channel Function in Epicardial Border Zone of Healing Canine Infarcts137
Smooth Muscle Cells Isolated From Discrete Compartments of the Mature Vascular Media Exhibit Unique Phenotypes and Distinct Growth Capabilities137
Expression Pattern of Connexin Gene Products at the Early Developmental Stages of the Mouse Cardiovascular System137
Sinoatrial Node Pacemaker Activity Requires Ca 2+ /Calmodulin-Dependent Protein Kinase II Activation137
Rhythmic Ryanodine Receptor Ca 2+ Releases During Diastolic Depolarization of Sinoatrial Pacemaker Cells Do Not Require Membrane Depolarization137
"Reperfusion injury" by oxygen-derived free radicals? Effect of superoxide dismutase plus catalase, given at the time of reperfusion, on myocardial infarct size, contractile function, coronary microva137
Caveolin-1 Facilitates Mechanosensitive Protein Kinase B (Akt) Signaling In Vitro and In Vivo137
Extracellular Matrix–Bound Angiopoietin-Like 4 Inhibits Endothelial Cell Adhesion, Migration, and Sprouting and Alters Actin Cytoskeleton137
Pulsatile Cardiac Tissue Grafts Using a Novel Three-Dimensional Cell Sheet Manipulation Technique Functionally Integrates With the Host Heart, In Vivo137
Effects of Overexpression of the Na + -Ca 2+ Exchanger on [Ca 2+ ] i 137
A role for endogenous endothelin-1 in neointimal formation after rat carotid artery balloon angioplasty. Protective effects of the novel nonpeptide endothelin receptor antagonist SB 209670.137
Endothelium-dependent relaxation in experimental atherosclerosis in the rabbit.136
Importance of E-Selectin for Firm Leukocyte Adhesion In Vivo136
Central and peripheral adrenergic mechanisms in the development of deoxycorticosterone-saline hypertension in rats.136
De Novo Synthesis of Myocardial Adenine Nucleotides in the Rat136
Effect of thyroid hormone on the expression of mRNA encoding sarcoplasmic reticulum proteins.136
Binding and Phagocytosis of Apoptotic Vascular Smooth Muscle Cells Is Mediated in Part by Exposure of Phosphatidylserine136
Regional differences in myocardial performance in the left ventricle of the dog.136
Hyperhomocysteinemia Activates Nuclear Factor-κB in Endothelial Cells via Oxidative Stress136
Pathophysiological consequences of atherosclerosis extend into the coronary microcirculation. Restoration of endothelium-dependent responses by L-arginine.136
Migration Inhibitory Factor Mediates Angiogenesis via Mitogen-Activated Protein Kinase and Phosphatidylinositol Kinase136
A Role for Reactive Oxygen Species in Endothelial Cell Anoikis136
Vascular Endothelial Growth Factor-B Promotes In Vivo Angiogenesis136
ARC Inhibits Cytochrome c Release From Mitochondria and Protects Against Hypoxia-Induced Apoptosis in Heart-Derived H9c2 Cells136
Tissue and Species Distribution of mRNA for the i kr -like K + Channel, ERG136
Changes in Shear Stress–Related Gene Expression After Experimentally Altered Venous Return in the Chicken Embryo136
Molecular Cloning and Characterization of the Intermediate-Conductance Ca 2+ -Activated K + Channel in Vascular Smooth Muscle136
Actions of adenosine and isoproterenol on isolated mammalian ventricular myocytes.136
Unidirectional block and reentry of cardiac excitation: a model study.135
Subendocardial Distribution of Coronary Blood Flow and the Effect of Antianginal Drugs135
Servoanalysis of Carotid Sinus Reflex Effects on Peripheral Resistance135
Depression of Ventricular Contractility by Stimulation of the Vagus Nerves135
The Development of the Atrioventricular Junction in the Human Heart135
Sarcoplasmic Reticulum and Nuclear Envelope Are One Highly Interconnected Ca 2+ Store Throughout Cardiac Myocyte135
Redox Changes of Cultured Endothelial Cells and Actin Dynamics135
Upper Limit of Autoregulation of Cerebral Blood Flow in the Baboon135
Opioid-Induced Second Window of Cardioprotection135
Identification of a Putative Microvascular Oxygen Sensor135
Role of Nitric Oxide in the Angiogenic Response In Vitro to Basic Fibroblast Growth Factor135
Important Role of Erythropoietin Receptor to Promote VEGF Expression and Angiogenesis in Peripheral Ischemia in Mice135
Rho-Associated Protein Kinase Contributes to Early Atherosclerotic Lesion Formation in Mice135
Small Artery Remodeling Depends on Tissue-Type Transglutaminase135
Role of Apoptosis in the Disappearance of Infiltrated and Proliferated Interstitial Cells After Myocardial Infarction135
Xanthine Oxidoreductase Inhibition Causes Reverse Remodeling in Rats With Dilated Cardiomyopathy135
cAMP-Dependent Vasodilators Cross-Activate the cGMP-Dependent Protein Kinase to Stimulate BK Ca Channel Activity in Coronary Artery Smooth Muscle Cells135
Glu298Asp Endothelial Nitric Oxide Synthase Gene Polymorphism Interacts With Environmental and Dietary Factors to Influence Endothelial Function135
Relaxin, a Pregnancy Hormone, Is a Functional Endothelin-1 Antagonist135
Quantification of coronary artery stenosis in vivo.134
Mechanism of flecainide's antiarrhythmic action in experimental atrial fibrillation.134
Role of Structural Barriers in the Mechanism of Alternans-Induced Reentry134
Angiotensin II induces fibronectin expression associated with cardiac fibrosis in the rat.134
The Limits of Right Ventricular Compensation Following Acute Increase in Pulmonary Circulatory Resistance134
Cardiac Alternans Do Not Rely on Diastolic Sarcoplasmic Reticulum Calcium Content Fluctuations134
Electrical Activity of Single Fibers of the Atrioventricular Node134
Effect of Epinephrine on Pressure, Flow, and Volume Relationships in the Systemic Circulation of Dogs134
Differential sensitivity of canine cardiac sarcolemmal and microsomal enzymes to inhibition by free radical-induced lipid peroxidation.134
Adrenomedullin Reduces Endothelial Hyperpermeability134
Cellular and Ionic Basis of Arrhythmias in Postinfarction Remodeled Ventricular Myocardium134
Hyperplastic Conotruncal Endocardial Cushions and Transposition of Great Arteries in Perlecan-Null Mice134
Spatial distribution of connexin43, the major cardiac gap junction protein, in the developing and adult rat heart.134
Reperfusion of Rat Heart After Brief Ischemia Induces Proteolysis of Calspectin (Nonerythroid Spectrin or Fodrin) by Calpain134
Epoxycyclopentenone-Containing Oxidized Phospholipids Restore Endothelial Barrier Function via Cdc42 and Rac134
An In Vivo Analysis of Hematopoietic Stem Cell Potential134
Cardiac-Specific Ablation of G-Protein Receptor Kinase 2 Redefines Its Roles in Heart Development and β-Adrenergic Signaling134
Longterm Exercise-Derived Exosomal miR-342-5p134
Mechanisms of neurogenic pulmonary edema.133
Specific Resistance of Body Tissues133
Compliance of the Human Pulmonary Arterial System in Disease133
Electrophysiological Actions of Lidocaine on Canine Ventricular Muscle and Purkinje Fibers133
Cyclic Adenosine Monophosphate Modulation of Slow Calcium Influx Channels in Guinea Pig Hearts133
Electrolyte Alterations in Acute Myocardial Ischemic Injury133
Aortic endothelial cell replication. I. Effects of age and hypertension in the rat.133
Ionic Mechanisms of Regional Action Potential Heterogeneity in the Canine Right Atrium133
Pharmacological analysis of 5-hydroxytryptamine receptors in isolated intracranial and extracranial vessels of cat and man.133
Impaired Cardiac Energetics in Mice Lacking Muscle-Specific Isoenzymes of Creatine Kinase133
KCNQ1 Assembly and Function Is Blocked by Long-QT Syndrome Mutations That Disrupt Interaction With Calmodulin133
Dlastolic Pressure-Volume Relationship in the Canine Left Ventricle133
Spatially Discordant Alternans in Cardiac Tissue133
ATP-Sensitive K + Channels, Adenosine, and Nitric Oxide–Mediated Mechanisms Account for Coronary Vasodilation During Exercise133
Role of Vascular Cell Adhesion Molecule-1 and Fibronectin Connecting Segment-1 in Monocyte Rolling and Adhesion on Early Atherosclerotic Lesions133
Static and dynamic components in the vascular myogenic response to passive changes in length as revealed by electrical and mechanical recordings from the rat portal vein.133
Susceptibility to Myocarditis Is Dependent on the Response of αβ T Lymphocytes to Coxsackieviral Infection133
Rho Family Small G Proteins Play Critical Roles in Mechanical Stress–Induced Hypertrophic Responses in Cardiac Myocytes133
Determination of Plasma Renin Concentration by Angiotensin I Immunoassay133
Dispersion of refractoriness in canine ventricular myocardium. Effects of sympathetic stimulation.133
Functional Adult Myocardium in the Absence of Na + -Ca 2+ Exchange133
Epidemiologic and Genetic Studies of Congenital Heart Disease in the Dog132
Innate Immunity and Angiogenesis132
Intimal ultrastructure of human umbilical arteries. Observations on arteries from newborn children of smoking and nonsmoking mothers.132
Central Nervous System Control of Baroreceptor Reflexes in the Rabbit132
Role of the intrarenal renin-angiotensin system in the control of renal function.132
Progressive ventricular remodeling in response to diffuse isoproterenol-induced myocardial necrosis in rats.132
Quantitative determination of regional oxygen consumption in the dog heart.132
Refractory Period of the Dog's Ventricular Myocardium Following Sudden Changes in Frequency132
FIZZ1/RELMα, a Novel Hypoxia-Induced Mitogenic Factor in Lung With Vasoconstrictive and Angiogenic Properties132
Microcirculation in the Ventricle of the Dog and Turtle132
The Stochastic Nature of Cardiac Propagation at a Microscopic Level132
The effects of geometry, elasticity, and external pressures on the diastolic pressure-volume and stiffness-stress relations. How important is the pericardium?132
Interaction of acidosis and increased extracellular potassium on action potential characteristics and conduction in guinea pig ventricular muscle.132
Application of Transcription Factor “Decoy” Strategy as Means of Gene Therapy and Study of Gene Expression in Cardiovascular Disease132
Time course for reversal of electrophysiological and ultrastructural abnormalities in subendocardial Purkinje fibers surviving extensive myocardial infarction in dogs.132
Inhibition of coronary artery superoxide dismutase attenuates endothelium-dependent and -independent nitrovasodilator relaxation.132
Nitric oxide synthase in cardiac nerve fibers and neurons of rat and guinea pig heart.132
Loaded Shortening, Power Output, and Rate of Force Redevelopment Are Increased With Knockout of Cardiac Myosin Binding Protein-C132
Hypoxia Inducible Factor-1 Activation by Prolyl 4-Hydroxylase-2 Gene Silencing Attenuates Myocardial Ischemia Reperfusion Injury132
Diabetes Mellitus Impairs Vasodilation to Hypoxia in Human Coronary Arterioles132
Malignant hypertension resulting from deoxycorticosterone acetate and salt excess: role of renin and sodium in vascular changes.132
Carbon Monoxide Dilates Cerebral Arterioles by Enhancing the Coupling of Ca 2+ Sparks to Ca 2+ -Activated K +132
Acute Antiinflammatory Properties of Statins Involve Peroxisome Proliferator–Activated Receptor-α via Inhibition of the Protein Kinase C Signaling Pathway132
Glucose-6-Phosphate Dehydrogenase Modulates Cytosolic Redox Status and Contractile Phenotype in Adult Cardiomyocytes132
Hypoxia-Induced Endothelial Apoptosis Through Nuclear Factor-κB (NF-κB)–Mediated bcl-2 Suppression132
Signaling by the Angiotensin-Converting Enzyme131
Is fibrillation chaos?131
Effects of Adenosine Compounds on Renal Function and Renin Secretion in Dogs131
Depressed Myocardial Creatine Phosphokinase Activity Following Experimental Myocardial Infarction in Rabbit131
Protective Role of Angiopoietin-1 in Experimental Pulmonary Hypertension131
Inverse calculation of QRS-T epicardial potentials from body surface potential distributions for normal and ectopic beats in the intact dog.131
Renal and systemic hemodynamic effects of synthetic atrial natriuretic peptide in the anesthetized rat.131
A Different Outlook on the Role of Bone Marrow Stem Cells in Vascular Growth131
Osteopontin Plays an Important Role in the Development of Medial Thickening and Neointimal Formation131
Different Signaling Pathways Induce Apoptosis in Endothelial Cells and Cardiac Myocytes During Ischemia/Reperfusion Injury131
Phosphoinositide-Dependent Kinase 1 and p21-Activated Protein Kinase Mediate Reactive Oxygen Species–Dependent Regulation of Platelet-Derived Growth Factor–Induced Smooth Muscle Cell Migration131
The Variable Arterial Pressure Response to Serotonin in Laboratory Animals and Man130
Postnatal changes in the circulation and responses to volume loading in sheep.130
Mechanism of Impaired Myocardial Function During Progressive Coronary Stenosis in Conscious Pigs130
Free radicals and reperfusion-induced arrhythmias: protection by spin trap agent PBN in the rat heart.130
Load regulation of the properties of adult feline cardiocytes: growth induction by cellular deformation.130
cAMP-Independent Dilation of Coronary Arterioles to Adenosine130
Effect of regional ischemia on the left ventricular end-systolic pressure-volume relationship of isolated canine hearts.130
Adenosine inhibits exocytotic release of endogenous noradrenaline in rat heart: a protective mechanism in early myocardial ischemia.130
Depressed Ryanodine Receptor Activity Increases Variability and Duration of the Systolic Ca 2+ Transient in Rat Ventricular Myocytes130
Ca 2+ -Dependent Rapid Ca 2+ Sensitization of Contraction in Arterial Smooth Muscle130
Volume regulation and plasma membrane injury in aerobic, anaerobic, and ischemic myocardium in vitro. Effects of osmotic cell swelling on plasma membrane integrity.130
Deficient Platelet-Derived Nitric Oxide and Enhanced Hemostasis in Mice Lacking the NOSIII Gene130
Effects of sodium pentobarbital anesthesia on left ventricular function and distribution of cardiac output in dogs, with particular reference to the mechanism for tachycardia.130
Bidirectional Role of Tumor Necrosis Factor-α in Coronary Microembolization130
Nitric Oxide Donors Induce Late Preconditioning Against Myocardial Stunning and Infarction in Conscious Rabbits via an Antioxidant-Sensitive Mechanism130
Rho Kinase Inhibition Improves Endothelial Function in Human Subjects With Coronary Artery Disease130
Enhanced Release of Prostaglandins Contributes to Flow-Induced Arteriolar Dilation in eNOS Knockout Mice130
Gap junction protein connexin40 is preferentially expressed in vascular endothelium and conductive bundles of rat myocardium and is increased under hypertensive conditions.130
Vascular free radical release. Ex vivo and in vivo evidence for a flow-dependent endothelial mechanism.130
Relationship Between Intracellular Calcium and Contractile Force in Stunned Myocardium130
Increased messenger RNA level of the inhibitory G protein alpha subunit Gi alpha-2 in human end-stage heart failure.130
Urokinase-Type Plasminogen Activator Plays a Critical Role in Angiotensin II–Induced Abdominal Aortic Aneurysm130
Novel Effect of Mineralocorticoid Receptor Antagonism to Reduce Proinflammatory Cytokines and Hypothalamic Activation in Rats With Ischemia-Induced Heart Failure130
A Sphingosine-1–Phosphate-Activated Calcium Channel Controlling Vascular Smooth Muscle Cell Motility130
Mitochondria Are a Subset of Extracellular Vesicles Released by Activated Monocytes and Induce Type I IFN and TNF Responses in Endothelial Cells130
Transmembrane Voltage Changes During Unipolar Stimulation of Rabbit Ventricle129
Angiotensin II Activates Phosphatidylinositol 3-Kinase in Vascular Smooth Muscle Cells129
Adenosine production in the ischemic kidney.129
DNA Synthesis and Mitoses in Coronary Collateral Vessels of the Dog129
Comparison of the myocardial uptake of a technetium-labeled isonitrile analogue and thallium.129
Stress-Activated Protein Kinases in Cardiovascular Disease129
Effects of Pulmonary Embolism on the Pulmonary Circulation With Special Reference to Arteriovenous Shunts in the Lung129
Volumes and Compliances Measured Simultaneously in the Right and Left Ventricles of the Dog129
Electrode radius predicts lesion radius during radiofrequency energy heating. Validation of a proposed thermodynamic model.129
Rapid Effect of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibition on Coronary Endothelial Function129
Effects of sympathetic and vagal nerves on recovery properties of the endocardium and epicardium of the canine left ventricle.129
Adenosine 3', 5'-Monophosphate-Dependent Membrane Phosphorylation129
Regional myocardial blood flow during exercise in dogs with chronic left ventricular hypertrophy.129
Effects of myocardial ischemia on quantitative ultrasonic backscatter and identification of responsible determinants.129
Reduced Atherosclerotic Plaque but Enhanced Aneurysm Formation in Mice With Inactivation of the Tissue Inhibitor of Metalloproteinase-1 ( TIMP-1 ) Gene129
Inhibition of Vascular Smooth Muscle Cell Migration by Cytochrome P450 Epoxygenase-Derived Eicosanoids129
Sensitization of the Adrenal Cortex to Angiotensin II in Sodium-Deplete Man129
Regulation of Ventricular Contraction129
Different activation of the endothelial L-arginine and cyclooxygenase pathway in the human internal mammary artery and saphenous vein.129
Peroxisome Proliferator–Activated Receptor Activators Inhibit Lipopolysaccharide-Induced Tumor Necrosis Factor-α Expression in Neonatal Rat Cardiac Myocytes129
Subcellular [Ca 2+ ] i Gradients During Excitation-Contraction Coupling in Newborn Rabbit Ventricular Myocytes129
Angiotensin II Induces Soluble fms-Like Tyrosine Kinase-1 Release via Calcineurin Signaling Pathway in Pregnancy129
Combined Loss of Hey1 and HeyL Causes Congenital Heart Defects Because of Impaired Epithelial to Mesenchymal Transition129
Endothelium-Dependent Contractions Are Associated With Both Augmented Expressionof Prostaglandin H Synthase-1 and Hypersensitivity to Prostaglandin H 2 in the SHR Ao129
Allele-Specific Regulation of Matrix Metalloproteinase-12 Gene Activity Is Associated With Coronary Artery Luminal Dimensions in Diabetic Patients With Manifest Coronary Artery Disease129
Increased Expression of Interleukin-1β and Monocyte Chemotactic and Activating Factor/Monocyte Chemoattractant Protein-1 in the Hypertrophied and Failing Heart With Pressure Overload129
Perturbations of Vascular Homeostasis and Aortic Valve Abnormalities in Fibulin-4 Deficient Mice129
Replacement by Homologous Recombination of the minK Gene With lacZ Reveals Restriction of minK Expression t129
Low Efficiency of Ca 2+ Entry Through the Na + -Ca 2+ Exchanger as Trigger for Ca <129
Histamine and cardiac arrhythmias.128
Signaling in Myocardial Hypertrophy128
Effects of the discrete pattern of electrical coupling on propagation through an electrical syncytium.128
S -Nitrosothiols in the Blood128
Significance of myocardial alpha- and beta-adrenoceptors in catecholamine-induced cardiac hypertrophy.128
Integrin Signaling Transduces Shear Stress-Dependent Vasodilation of Coronary Arterioles128
Apolipoprotein E Suppresses the Type I Inflammatory Response In Vivo128
Hemodynamics of arterial stenoses at elevated flow rates.128
Cyclic guanosine monophosphate-enhanced sequestration of Ca2+ by sarcoplasmic reticulum in vascular smooth muscle.128
Myeloperoxidase Delays Neutrophil Apoptosis Through CD11b/CD18 Integrins and Prolongs Inflammation128
Nonexocytotic release of endogenous noradrenaline in the ischemic and anoxic rat heart: mechanism and metabolic requirements.128
Genetic Influence of the Kidneys on Blood Pressure128
Aldosterone and Angiotensin II Synergistically Induce Mitogenic Response in Vascular Smooth Muscle Cells128
Reflex inputs to the cardiovascular and respiratory centers from dynamically working canine muscles. Some evidence for involvement of group III or IV nerve fibers.128
Mechanism of Doxorubicin-Induced Inhibition of Sarcoplasmic Reticulum Ca 2+ -ATPase Gene Transcription128
Vascular Endothelial Growth Factor–Induced Endothelial Cell Migration and Proliferation Depend on a Nitric Oxide–Mediated Decrease in Protein Kinase Cδ Activity128
Respiratory modulation of muscle sympathetic nerve activity in intact and lung denervated humans.128
Hydrogen Peroxide Activates Mitogen-Activated Protein Kinases and Na + -H + Exchange in Neonatal Rat Cardiac Myocytes128
Angiopoietin-1 Opposes VEGF-Induced Increase in Endothelial Permeability by Inhibiting TRPC1-Dependent Ca 2 Influx128
Function and Production of Nitric Oxide in the Coronary Circulation of the Conscious Dog During Exercise128
Rapid Inactivation Determines the Rectification and [K + ] o Dependence of the Rapid Component of the Delayed Rectifier K 128
Overexpression of the Cardiac Na + /Ca 2+ Exchanger Increases Susceptibility to Ischemia/Reperfusion Injury in Male, but Not Femal128
Abnormal Calcium Signaling and Sudden Cardiac Death Associated With Mutation of Calsequestrin128
Novel LQT-3 Mutation Affects Na + Channel Activity Through Interactions Between α- and β 1 -Subunits128
Stretch Enhances Contraction of Bovine Coronary Arteries via an NAD(P)H Oxidase–Mediated Activation of the Extracellular Signal–Regulated Kinase Mitogen-Activated Protein Kinase Cascade128
Effects of Intra-Aortic Balloon Counterpulsation on Cardiac Performance, Oxygen Consumption, and Coronary Blood Flow in Dogs128
Arteriogenesis Proceeds via ICAM-1/Mac-1- Mediated Mechanisms128
Differential Changes in Cardiac Phospholamban and Sarcoplasmic Reticular Ca 2+ -ATPase Protein Levels128
Pulmonary edema due to increased microvascular permeability to fluid and protein.127
Inhibition of Coronary Vasodilating Action of Dipyridamole and Adenosine by Aminophylline in the Dog127
Oxygen Uptake of the Nonworking Left Ventricle127
Reversibly injured, postischemic canine myocardium retains normal contractile reserve.127
Platelet aggregation in the cerebral microcirculation: effect of aspirin and other agents.127
Lipid Depletion in Atheromatous Coronary Arteries in Rhesus Monkeys after Regression Diets127
Late sodium current and its contribution to action potential configuration in guinea pig ventricular myocytes.127
Static Anisotropic Elastic Properties of the Aorta in Living Dogs127
Intra- and extracellular actions of proton on the calcium current of isolated guinea pig ventricular cells.127
Localized Expression of Aromatase in Human Vascular Tissues127
Pulsatile Stretch Remodels Cell-to-Cell Communication in Cultured Myocytes127
Reversibility of diabetic cardiomyopathy with insulin in rats.127
A model study of the effects of the discrete cellular structure on electrical propagation in cardiac tissue.127
Triggered ventricular rhythms in 1-day-old myocardial infarction in the dog.127
Increased Microvascular Reactivity and Improved Mortality in Septic Mice Lacking Inducible Nitric Oxide Synthase127
Mechanics of Distension of Dog Veins and Other Very Thin-Walled Tubular Structures127
Pulsatile Stretch Stimulates Superoxide Production and Activates Nuclear Factor-κB in Human Coronary Smooth Muscle127
Relationship between adenine nucleotide metabolism and irreversible ischemic tissue damage in isolated perfused rat heart.127
Platelet-derived growth factor-BB-induced suppression of smooth muscle cell differentiation.127
Connexin43 and Connexin45 Form Heteromeric Gap Junction Channels in Which Individual Components Determine Permeability and Regulation127
Superoxide generation and reversal of acetylcholine-induced cerebral arteriolar dilation after acute hypertension.127
Glycated Collagen I Induces Premature Senescence-Like Phenotypic Changes in Endothelial Cells127
Redundancy reduction for improved display and analysis of body surface potential maps. I. Spatial compression.127
Atrial natriuretic factor and isosorbide dinitrate modulate the gating of ATP-sensitive K+ channels in cultured vascular smooth muscle cells.127
Very Low-Density Lipoprotein Activates Nuclear Factor-κB in Endothelial Cells127
Matrix Metalloproteinase-3 Genotype Contributes to Age-Related Aortic Stiffening Through Modulation of Gene and Protein Expression127
Effects of chronic inhibition of converting enzyme on mechanical and structural properties of arteries in rat renovascular hypertension.127
Induction of Heat Shock Response Protects the Heart Against Atrial Fibrillation127
Management of Myocarditis-Related Cardiomyopathy in Adults127
Arrhythmogenicity of IgG and Anti-52-kD SSA/Ro Affinity-Purified Antibodies From Mothers of Children With Congenital Heart Block127
Plasma Nitrosothiols Contribute to the Systemic Vasodilator Effects of Intravenously Applied NO127
Hyperhomocysteinemia Decreases Circulating High-Density Lipoprotein by Inhibiting Apolipoprotein A-I Protein Synthesis and Enhancing HDL Cholesterol Clearance127
O 2 Sensing in the Human Ductus Arteriosus127
Combination of Tumor Necrosis Factor-α Ablation and Matrix Metalloproteinase Inhibition Prevents Heart Failure After Pressure Overload in Tissue Inhibitor of Metalloproteinase-3 Knock-Out Mice127
Integrin-Linked Kinase at the Heart of Cardiac Contractility, Repair, and Disease126
The ε Subtype of Protein Kinase C Is Required for Cardiomyocyte Connexin-43 Phosphorylation126
Role of Central and Peripheral Adrenergic Mechanisms in Neurogenic Hypertension Produced by Brainstem Lesions in Rat126
Effects of acidosis on ventricular muscle from adult and neonatal rats.126
Intracellular Sodium Accumulation During Ischemia as the Substrate for Reperfusion Injury126
Isoform-Specific Modulation of Voltage-Gated Na + Channels by Calmodulin126
Ryanodine alteration of the contractile state of rat ventricular myocardium. Comparison with dog, cat, and rabbit ventricular tissues.126
The effects of gonadectomy on left ventricular function and cardiac contractile proteins in male and female rats.126
Tenascin-C Is Induced With Progressive Pulmonary Vascular Disease in Rats and Is Functionally Related to Increased Smooth Muscle Cell Proliferation126
Altered left atrial compliance after atrial appendectomy. Influence on left atrial and ventricular filling.126
Alteration of contractile function and excitation-contraction coupling in dilated cardiomyopathy.126
Regional Distribution of Diffusible Tracers and Carbonized Microspheres in the Left Ventricle of Isolated Dog Hearts126
Effect of Bicycling on the Baroreflex Regulation of Pulse Interval126
Estrogens and Glucocorticoids Inhibit Endothelial Vascular Cell Adhesion Molecule-1 Expression by Different Transcriptional Mechanisms126
Activated Protein C Induces Endothelial Cell Proliferation by Mitogen-Activated Protein Kinase Activation In Vitro and Angiogenesis In Vivo126
Cardiac Myocyte Apoptosis Is Associated With Increased DNA Damage and Decreased Survival in Murine Models of Obesity126
Nitric Oxide Can Increase Heart Rate by Stimulating the Hyperpolarization-Activated Inward Current, I f125
Endogenous p53 Protects Vascular Smooth Muscle Cells From Apoptosis and Reduces Atherosclerosis in ApoE Knockout Mice125
Molecular Mechanisms of Anoxia/Reoxygenation-Induced Neutrophil Adherence to Cultured Endothelial Cells125
Effect of Cigarette Smoking and Nicotine on Serum Free Fatty Acids125
Mechanically Driven Contour-Length Adjustment in Rat Cardiac Titin’s Unique N2B Sequence125
Hemodynamic and Metabolic Effects of Hemorrhage in Man, with Particular Reference to the Splanchnic Circulation125
Protein Kinase A Phosphorylation at Serine-2808 of the Cardiac Ca 2+ -Release Channel (Ryanodine Receptor) Does Not Dissociate 12.6-kDa FK506-Binding Protein (FKBP12125
Frequency- and Afterload-Dependent Cardiac Modulation In Vivo by Troponin I With Constitutively Active Protein Kinase A Phosphorylation Sites125
Unique Kir2.x Properties Determine Regional and Species Differences in the Cardiac Inward Rectifier K + Current125
Soluble Transforming Growth Factor-β Type II Receptor Inhibits Negative Remodeling, Fibroblast Transdifferentiation, and Intimal Lesion Formation But Not Endothelial Growth125
Familial Hypertrophic Cardiomyopathy-Linked Mutant Troponin T Causes Stress-Induced Ventricular Tachycardia and Ca 2+ -Dependent Action Potential Remodeling125
Selective Activation of A 3 Adenosine Receptors With N 6 -(3-Iodobenzyl)Adenosine-5′- N 125
Effects of Recombinant Adenovirus-Mediated Uncoupling Protein 2 Overexpression on Endothelial Function and Apoptosis125
Electrical Excitability of Atrioventricular Nodal Cells125
Cardioversion and Digitalis Drugs: Changed Threshold to Electric Shock in Digitalized Animals125
Adenine nucleotide release from isolated perfused guinea pig hearts and extracellular formation of adenosine.125
Induction of Cardiogenesis in Embryonic Stem Cells via Downregulation of Notch1 Signaling125
Protective Action of Methylprednisolone on the Myocardium during Experimental Myocardial Ischemia in the Cat125
Effects of Norepinephrine on Coronary Circulation and Left Ventricular Dynamics in the Conscious Dog125
Myosin Crossbridge Activation of Cardiac Thin Filaments125
Supernormal excitability as a mechanism of chaotic dynamics of activation in cardiac Purkinje fibers.125
Withdrawal of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors Elicits Oxidative Stress and Induces Endothelial Dysfunction in Mice125
Alterations in the Determinants of Diastolic Suction During Pacing Tachycardia125
Effects of preload on the transmural distribution of perfusion and pressure-flow relationships in the canine coronary vascular bed.125
Enhanced Dispersion of Repolarization and Refractoriness in Transgenic Mouse Hearts Promotes Reentrant Ventricular Tachycardia125
Homocysteine Mediated Expression and Secretion of Monocyte Chemoattractant Protein-1 and Interleukin-8 in Human Monocytes125
Mechanistically Distinct Steps in the Mitochondrial Death Pathway Triggered by Oxidative Stress in Cardiac Myocytes125
Microvascular Responses to Alterations in Oxygen Tension124
Comparative antioxidant activities of propranolol, nifedipine, verapamil, and diltiazem against sarcolemmal membrane lipid peroxidation.124
Liver and ductus venosus blood flows in fetal lambs in utero.124
Canine Lipoproteins and Atherosclerosis124
Vessel caliber and branch-angle of human coronary artery branch-points.124
Series Elasticity in Heart Muscle124
Observations on the Control of Cerebral Blood Flow in the Sheep Fetus and Newborn Lamb124
Effects of acetylsalicylic acid on the ductus arteriosus and circulation in fetal lambs in utero.124
A Specific Competitive Antagonist of the Vascular Action of Angiotensin II124
Selective In Situ Parasympathetic Control of the Canine Sinoatrial and Atrioventricular Nodes124
Glucose Enhances Human Macrophage LOX-1 Expression124
Hibernating Myocardium124
Endothelium-dependent relaxation and cyclic GMP accumulation in rabbit pulmonary artery are selectively impaired by moderate hypoxia.124
Purinergic axis in cardiac blood vessels. Agonist-mediated release of ATP from cardiac endothelial cells.124
Urokinase but Not Tissue Plasminogen Activator Mediates Arterial Neointima Formation in Mice124
Induction of insulin-like growth factor I messenger RNA in rat aorta after balloon denudation.124
Platelets Release CXCL4L1, a Nonallelic Variant of the Chemokine Platelet Factor-4/CXCL4 and Potent Inhibitor of Angiogenesis124
Natural course of the impairment of endothelium-dependent relaxations after balloon endothelium removal in porcine coronary arteries. Possible dysfunction of a pertussis toxin-sensitive G protein.124
Cardiac-Specific Ablation of the Na + -Ca 2+ Exchanger Confers Protection Against Ischemia/Reperfusion Injury124
Myostatin Regulates Cardiomyocyte Growth Through Modulation of Akt Signaling124
Restricted distribution of connexin40, a gap junctional protein, in mammalian heart.124
Intrasarcoplasmic Amyloidosis Impairs Proteolytic Function of Proteasomes in Cardiomyocytes by Compromising Substrate Uptake124
Heparin Blockade of Thrombin-Induced Smooth Muscle Cell Migration Involves Inhibition of Epidermal Growth Factor (EGF) Receptor Transactivation by Heparin-Binding EGF-Like Growth Factor124
Endogenous Endothelial Nitric Oxide Synthase–Derived Nitric Oxide Is a Physiological Regulator of Myocardial Oxygen Consumption124
Tissue Engineering Therapy for Cardiovascular Disease123
Vascular Cell Apoptosis in Remodeling, Restenosis, and Plaque Rupture123
Big Mitogen-Activated Protein Kinase (BMK1)/ERK5 Protects Endothelial Cells From Apoptosis123
Mechanism of adenosine-mediated decreases in glomerular filtration rate in dogs.123
Cytoskeletal Mechanics in Pressure-Overload Cardiac Hypertrophy123
Optical recordings in the rabbit heart show that defibrillation strength shocks prolong the duration of depolarization and the refractory period.123
Regulation of Blood Pressure by Sympathetic Nerve Fibers and Adrenal Medulla in Normotensive and Hypertensive Rats123
Influence of Pulmonary Arterial and Left Atrial Pressures on Pulmonary Vascular Resistance123
Effects of Rapamycin on Ryanodine Receptor/Ca 2+ -Release Channels From Cardiac Muscle123
Individual Gap Junction Plaques Contain Multiple Connexins in Arterial Endothelium123
Reversal of Pulmonary Hypertension by Prolonged Oxygen Administration to Patients with Chronic Bronchitis123
Plasma catecholamines during paroxysmal neurogenic hypertension in quadriplegic man.123
Myocardin Induces Cardiomyocyte Hypertrophy123
Role of kinins and nitric oxide in the effects of angiotensin converting enzyme inhibitors on neointima formation.123
Morphometry of canine coronary arteries, arterioles, and capillaries during hypertension and left ventricular hypertrophy.123
Inhibition of Hydroxymethylglutaryl-Coenzyme A Reductase Reduces Th1 Development and Promotes Th2 Development123
Regionalized Sequence of Myocardial Cell Growth and Proliferation Characterizes Early Chamber Formation123
Nitric Oxide-20–Hydroxyeicosatetraenoic Acid Interaction in the Regulation of K + Channel Activity and Vascular Tone in Renal Arterioles123
Angiotensin II Receptor–Independent Antiinflammatory and Antiaggregatory Properties of Losartan123
Central Role of Connexin40 in the Propagation of Electrically Activated Vasodilation in Mouse Cremasteric Arterioles In Vivo123
Expression of Human Scavenger Receptor Class B Type I in Cultured Human Monocyte-Derived Macrophages and Atherosclerotic Lesions123
Regulation of Endocytic Recycling of KCNQ1/KCNE1 Potassium Channels123
In Vivo Thrombus Formation in Murine Models122
Vascular gp91 phox 122
A Mechanism for Reentry in Canine Ventricular Tissue122
Programming Smooth Muscle Plasticity With Chromatin Dynamics122
Propagated Vasodilation in the Microcirculation of the Hamster Cheek Pouch122
In situ analysis of alpha-adrenoceptors on arteriolar and venular smooth muscle in rat skeletal muscle microcirculation.122
Regulation of Endothelial Matrix Metalloproteinase-2 by Hypoxia/Reoxygenation122
Elevated Homocysteine Reduces Apolipoprotein A-I Expression in Hyperhomocysteinemic Mice and in Males With Coronary Artery Disease122
Calcium Current Channels Induced by Catecholamines in Chick Embryonic Hearts Whose Fast Sodium Channels are Blocked by Tetrodotoxin or Elevated Potassium122
Effects of Alterations in Aortic Impedance on the Performance of the Ventricles122
Hormone interactions in the isolated rabbit heart. Synthesis and coronary vasomotor effects of prostaglandins, angiotensin, and bradykinin.122
Epicardial mapping of ventricular defibrillation with monophasic and biphasic shocks in dogs.122
Signaling Properties and Functions of Two Distinct Cardiomyocyte Protease-Activated Receptors122
Involvement of Rho GTPases in the Transcriptional Inhibition of Preproendothelin-1 Gene Expression by Simvastatin in Vascular Endothelial Cells122
Oxygen Sensitivity of Cloned Voltage-Gated K + Channels Expressed in the Pulmonary Vasculature122
Reconstituted Human Cardiac K ATP Channels122
Total ischemia in dog hearts, in vitro 2. High energy phosphate depletion and associated defects in energy metabolism, cell volume regulation, and sarcolemmal integrity.122
Kappa and delta opioid receptor stimulation affects cardiac myocyte function and Ca2+ release from an intracellular pool in myocytes and neurons.122
Nitric oxide-mediated effects of interleukin-6 on [Ca2+]i and cell contraction in cultured chick ventricular myocytes.122
β 1 Integrins Participate in the Hypertrophic Response of Rat Ventricular Myocytes122
Changes in intramyocardial ST segment voltage and gas tensions with regional myocardial ischemia in the dog.122
Interdependent Serotonin Transporter and Receptor Pathways Regulate S100A4/Mts1, a Gene Associated With Pulmonary Vascular Disease122
Oxidative Stress–Induced Iron Signaling Is Responsible for Peroxide-Dependent Oxidation of Dichlorodihydrofluorescein in Endothelial Cells122
Rapamycin Inhibits α 1 -Adrenergic Receptor–Stimulated Cardiac Myocyte Hypertrophy but Not Activation of Hypertrophy-Associated Genes122
Volatile anesthetics block intercellular communication between neonatal rat myocardial cells.121
Distribution of the Coronary Blood Flow across the Canine Heart Wall during Systole121
Action of Manganese Ions and Tetrodotoxin on Atrioventricular Nodal Transmembrane Potentials in Isolated Rabbit Hearts121
Increased size of myocardial infarction in dogs with chronic hypertension and left ventricular hypertrophy.121
Histochemical and Chemical Studies of the Localization of Adrenergic and Cholinergic Nerves in Normal and Denervated Cat Hearts121
Potential arrhythmogenic electrophysiological derangements in canine Purkinje fibers induced by lysophosphoglycerides.121
Osmotic Compression of Single Cardiac Myocytes Eliminates the Reduction in Ca 2+ Sensitivity of Tension at Short Sarcomere Length121
Effects of Pressure-Induced Stretch and Convection on Low-Density Lipoprotein and Albumin Uptake in the Rabbit Aortic Wall121
Chemiluminescent Detection of Oxidants in Vascular Tissue121
Cardiac V 1 And V 3 Myosins Differ in Their Hydrolytic and Mechanical Activities In Vitro121
Stimulation of skin sympathetic nerve discharge by central command. Differential control of sympathetic outflow to skin and skeletal muscle during static exercise.121
High-Density Lipoproteins Protect Isolated Rat Hearts From Ischemia-Reperfusion Injury by Reducing Cardiac Tumor Necrosis Factor-α Content and Enhancing Prostaglandin Release121
Dual Channel Optical Tomographic Imaging of Leukocyte Recruitment and Protease Activity in the Healing Myocardial Infarct121
Deregulated expression of the c-myc oncogene abolishes inhibition of proliferation of rat vascular smooth muscle cells by serum reduction, interferon-gamma, heparin, and cyclic nucleotide analogues an121
Depletion of Mitogen-Activated Protein Kinase Using an Antisense Oligodeoxynucleotide Approach Downregulates the Phenylephrine-Induced Hypertrophic Response in Rat Cardiac Myocytes121
Polymorphisms of the β 2 -Adrenergic Receptor Determine Exercise Capacity in Patients With Heart Failure121
Wall shear stress temporal gradient and anastomotic intimal hyperplasia.120
GDF15, a Cardioprotective TGF-β Superfamily Protein120
Branching patterns in the porcine coronary arterial tree. Estimation of flow heterogeneity.120
Characterization of the renin-aldosterone system in decompensated cirrhosis.120
Protein kinase C modulates basal myogenic tone in resistance arteries from the cerebral circulation.120
Altered ion transport in aortic smooth muscle during deoxycorticosterone acetate hypertension in the rat.120
Engineering Mechanics for Successive States in Canine Left Ventricular Myocardium120
Effect of Left Ventricular Hypertension, Ischemia and Vasoactive Drugs on the Myocardial Distribution of Coronary Flow120
Heterogeneity of the action potential in isolated rat ventricular myocytes and tissue.120
Influence of a Pyrimidopyrimidine Derivative on Deamination of Adenosine by Blood120
A computer study of the left ventricular performance based on fiber structure, sarcomere dynamics, and transmural electrical propagation velocity.120
Coronary blood flow in experimental canine left ventricular hypertrophy.120
Adenine nucleotide metabolism and compartmentalization in isolated adult rat heart cells.120
Nongenomic Effects of Aldosterone on Intracellular Ca 2+ in Vascular Smooth Muscle Cells120
Myocardial composition and function in diabetes. The effects of chronic insulin use.120
Autonomic Control of Cardiac Action Potentials120
Divergent Roles of Angiotensin II AT 1 and AT 2 Receptors in Modulating Coronary Microvascular Function120
Does Nitric Oxide Mediate the Vasodilator Activity of Nitroglycerin?120
Immune Cell Toll-Like Receptor 4 Is Required for Cardiac Myocyte Impairment During Endotoxemia120
Targeted Disruption of Smad4 in Cardiomyocytes Results in Cardiac Hypertrophy and Heart Failure120
Energetics of isometric force development in control and volume-overload human myocardium. Comparison with animal species.120
Velocity profiles of blood platelets and red blood cells flowing in arterioles of the rabbit mesentery.120
Mimicking Phosphorylation of αB-Crystallin on Serine-59 Is Necessary and Sufficient to Provide Maximal Protection of Cardiac Myocytes From Apoptosis120
Circ_Lrp6, a Circular RNA Enriched in Vascular Smooth Muscle Cells, Acts as a Sponge Regulating miRNA-145 Function120
The cardiac and vascular factors that determine systemic blood flow.119
The structural and molecular basis of glomerular filtration.119
Cardiac contractile proteins. Adenosine triphosphatase activity and physiological function.119
Elastic Environment of the Capillary Bed119
Maximum Velocity as an Index of Contractility in Cardiac Muscle119
Endothelial renin-angiotensin pathway: evidence for intracellular synthesis and secretion of angiotensins.119
Effect of stellectomy and vagotomy on ventricular refractoriness in dogs.119
Cardiac Gap Junction Channels Show Quantitative Differences in Selectivity119
Nuclear uptake of sex steroid hormones in the cardiovascular system of the baboon.119
Extraction, Purification, and Assay of Human Renin Free of Angiotensinase119
Rho GTPases and Leukocyte Adhesion Receptor Expression and Function in Endothelial Cells119
Quantitative Studies of Microcirculatory Structure and Function119
Granulocytes and no-reflow phenomenon in irreversible hemorrhagic shock.119
Redistribution of Renal Blood Flow Produced by Furosemide and Ethacrynic Acid119
High-Frequency Periodic Sources Underlie Ventricular Fibrillation in the Isolated Rabbit Heart119
Effect of pacing-induced ischemia on left ventricular diastolic pressure-volume relations in dogs with coronary stenoses.119
Catecholamine-Induced Vascular Wall Growth Is Dependent on Generation of Reactive Oxygen Species119
The effects of atrial fibrillation on atrial pressure-volume and flow relationships.119
Regulation of norepinephrine release from cardiac sympathetic fibers in the dog by presynaptic alpha- and beta-receptors.119
Is a High Glycogen Content Beneficial or Detrimental to the Ischemic Rat Heart?119
Mutation of N-myristoylation site converts endothelial cell nitric oxide synthase from a membrane to a cytosolic protein.119
Multiple connexins confer distinct regulatory and conductance properties of gap junctions in developing heart.119
Formation of F 2 -Isoprostanes During Oxidation of Human Low-Density Lipoprotein and Plasma by Peroxynitrite119
Ignition of Calcium Sparks in Arterial and Cardiac Muscle Through Caveolae119
1α,25-Dihydroxyvitamin D 3 Induces Vascular Smooth Muscle Cell Migration via Activation of Phosphatidylinositol 3-Kinase119
Aspirin Attenuates Cytomegalovirus Infectivity and Gene Expression Mediated by Cyclooxygenase-2 in Coronary Artery Smooth Muscle Cells119
Selective beta 1-adrenoceptor blockade enhances positive inotropic responses to endogenous catecholamines mediated through beta 2-adrenoceptors in human atrial myocardium.119
The effects of antiarrhythmic drugs, stimulation frequency, and potassium-induced resting membrane potential changes on conduction velocity and dV/dtmax in guinea pig myocardium.119
Glycogen-Synthase Kinase3β/β-Catenin Axis Promotes Angiogenesis Through Activation of Vascular Endothelial Growth Factor Signaling in Endothelial Cells119
Role of Heteromultimers in the Generation of Myocardial Transient Outward K + Currents119
Site of Origin and Molecular Substrate of Atrioventricular Junctional Rhythm in the Rabbit Heart119
Impaired Angiogenesis in Glutathione Peroxidase-1–Deficient Mice Is Associated With Endothelial Progenitor Cell Dysfunction119
Modulation of Ventricular Repolarization by a Premature Stimulus119
CD36 Mediates the Cardiovascular Action of Growth Hormone-Releasing Peptides in the Heart119
Osteopontin and β 3 Integrin Are Coordinately Expressed in Regenerating Endothelium In Vivo and Stimulate Arg-Gly-Asp–Dependent Endothelial Migration In Vitro119
Effect of autonomic blockade on ventricular refractoriness and atrioventricular nodal conduction in humans. Evidence supporting a direct cholinergic action on ventricular muscle refractoriness.119
Modulation of Iron Uptake in Heart by L-Type Ca 2+ Channel Modifiers119
Common Variants in Myocardial Ion Channel Genes Modify the QT Interval in the General Population119
Cyclic nucleotides and cardiac function.118
Nature of the Inotropic Action of Angiotensin on Ventricular Myocardium118
Rabbit papillary muscle myosin isozymes and the velocity of muscle shortening.118
Formation of Heterotypic Gap Junction Channels by Connexins 40 and 43118
Functional Properties of the Atrioventricular Conduction System118
Glucose flux rate regulates onset of ischemic contracture in globally underperfused rat hearts.118
Intrarenal Distribution of Blood Flow in Dogs during Hemorrhagic Hypotension118
Applications of the Lagged Normal Density Curve as a Model for Arterial Dilution Curves118
The Pathway of Ventricular Depolarization in the Dog118
Cellular uncoupling can unmask dispersion of action potential duration in ventricular myocardium. A computer modeling study.118
Increased Pulmonary Vascular Resistance in the Dependent Zone of the Isolated Dog Lung Caused by Perivascular Edema118
Deletion of Macrophage LDL Receptor–Related Protein Increases Atherogenesis in the Mouse118
The relationship of human atrial cellular electrophysiology to clinical function and ultrastructure.118
Shortening of the action potential and reduction of pacemaker activity by lidocaine, quinidine, and procainamide in sheep cardiac purkinje fibers. An effect on Na or K currents?118
Surface staining and cytotoxic activity of heat-shock protein 60 antibody in stressed aortic endothelial cells.118
Heme Oxygenase-1 Attenuates Glucose-Mediated Cell Growth Arrest and Apoptosis in Human Microvessel Endothelial Cells118
Mechanism for the postive inotropic effect of angiotensin II on isolated cardiac muscle.118
Vitamin D 3 –Upregulated Protein-1 (VDUP-1) Regulates Redox-Dependent Vascular Smooth Muscle Cell Proliferation Through Interaction With Thioredoxin118
Functional Consequences of Elimination of I to, f and I to, s118
Parasympathetic Control of Coronary Blood Flow in Dogs117
Fibrillation Threshold of Premature Ventricular Responses117
Genetics of Variation in HDL Cholesterol in Humans and Mice117
Regulation of muscle transcription by the MyoD family. The heart of the matter.117
Prospects for Gene Therapy for Heart Failure117
Coronary pressure-flow relationships. Controversial issues and probable implications.117
Antisense nonmuscle myosin heavy chain and c-myb oligonucleotides suppress smooth muscle cell proliferation in vitro.117
Modulation by prostaglandin synthesis inhibitors of the action of exogenous angiotensin II on glomerular ultrafiltration in the rat.117
Decreased hydrodynamic resistance in the two-phase flow of blood through small vertical tubes at low flow rates.117
Expression of Multiple Connexins in Cultured Neonatal Rat Ventricular Myocytes117
Modulation of Extracellular Superoxide Dismutase Expression by Angiotensin II and Hypertension117
In vivo adenoviral vector-mediated gene transfer into balloon-injured rat carotid arteries.117
Relation of mitochondrial and cytosolic free calcium to cardiac myocyte recovery after exposure to anoxia.117
Jumonji, a Nuclear Protein That Is Necessary for Normal Heart Development117
Decreased Energy Reserve in an Animal Model of Dilated Cardiomyopathy117
Human Coronary Arteriolar Dilation to Arachidonic Acid Depends on Cytochrome P-450 Monooxygenase and Ca 2+ -Activated K + Channels117
Inhibition of Endogenous Mst1 Prevents Apoptosis and Cardiac Dysfunction Without Affecting Cardiac Hypertrophy After Myocardial Infarction117
Mapping the conversion of atrial flutter to atrial fibrillation and atrial fibrillation to atrial flutter. Insights into mechanisms.117
Diabetes Induces Endothelial Dysfunction but Does Not Increase Neointimal Formation in High-Fat Diet Fed C57BL/6J Mice117
Chronic Hypoxia Activates Lung 15-Lipoxygenase, Which Catalyzes Production of 15-HETE and Enhances Constriction in Neonatal Rabbit Pulmonary Arteries117
Regulation of Murine Cardiac 20S Proteasomes117
Inducible Nitric Oxide Synthase Modulates Cyclooxygenase-2 Activity in the Heart of Conscious Rabbits During the Late Phase of Ischemic Preconditioning117
Vanilloid Receptor TRPV1, Sensory C-Fibers, and Vascular Autoregulation117
Endothelial PAS Domain Protein 1 Gene Promotes Angiogenesis Through the Transactivation of Both Vascular Endothelial Growth Factor and Its Receptor, Flt-1117
Targeted Deletion of Kv4.2 Eliminates I to,f and Results in Electrical and Molecular Remodeling, With No Evidence of Ventricular Hypertrophy or My117
Mechanisms of Action of Antiarrhythmic Drugs116
A Concurrent Flow Model for Extraction during Transcapillary Passage116
Intimal Thickening After Ligature of Arteries An Electron-Microscopic Study116
Murine Cardiac Function116
Role of nitric oxide in reactive hyperemia of the guinea pig heart.116
Influence of Coronary Artery Pressure Upon Myocardial Elasticity116
Short-term diabetes alters K+ currents in rat ventricular myocytes.116
Effects of Intracellular Angiotensin II in Vascular Smooth Muscle Cells116
Blockade of the ATP-sensitive potassium channel modulates reactive hyperemia in the canine coronary circulation.116
Inhibition of the activation and troponin calcium binding of dog cardiac myofibrils by acidic pH.116
Protective effect of vagal stimulation on reperfusion arrhythmias in cats.116
Effect of coronary blood flow on glycolytic flux and intracellular pH in isolated rat hearts.116
Polarographic Oxygen, the Epicardial Electrocardiogram and Muscle Contraction in Experimental Acute Regional Ischemia of the Left Ventricle116
Suppression of time-dependent outward current in guinea pig ventricular myocytes. Actions of quinidine and amiodarone.116
Simulation of Action Potentials From Metabolically Impaired Cardiac Myocytes116
Differential effects of adenosine and nitroglycerin on the action potentials of large and small coronary arteries.116
Endothelin blocks ATP-sensitive K+ channels and depolarizes smooth muscle cells of porcine coronary artery.116
C-Reactive Protein Enhances LOX-1 Expression in Human Aortic Endothelial Cells116
Cyclic Strain Inhibits Notch Receptor Signaling in Vascular Smooth Muscle Cells In Vitro116
Cell Cycle-Dependent Expression of L- and T-Type Ca 2+ Currents in Rat Aortic Smooth Muscle Cells in Primary Culture116
Impaired Atrial Receptor Responses in Dogs with Heart Failure Due to Tricuspid Insufficiency and Pulmonary Artery Stenosis116
Renin, Aldosterone, Body Fluid Volumes, and the Baroreceptor Reflex in the Development and Reversal of Goldblatt Hypertension in Conscious Dogs116
q and Gβγ Regulate PAR-1 Signaling of Thrombin-Induced NF-κB Activation and ICAM-1 Transcription in Endothelial Cells116
Phosphorylation of Serine 188 Protects RhoA from Ubiquitin/Proteasome-Mediated Degradation in Vascular Smooth Muscle Cells115
Endothelial Nox2 Overexpression Potentiates Vascular Oxidative Stress and Hemodynamic Response to Angiotensin II115
Gene Transfer of Extracellular Superoxide Dismutase Reduces Arterial Pressure in Spontaneously Hypertensive Rats115
Cystatin C Deficiency Increases Elastic Lamina Degradation and Aortic Dilatation in Apolipoprotein E–Null Mice115
Small Guanine Nucleotide-Binding Proteins and Myocardial Hypertrophy115
The Role of Electroporation in Defibrillation115
Baroreceptor reflexes in human hypertension.115
Catecholamine Metabolism in Experimental Hypertension in the Rat115
Inward Rectification and Implications for Cardiac Excitability115
Voltage dependence of intracellular [Ca2+]i transients in guinea pig ventricular myocytes.115
Left Ventricular Pressure -Volume Relationships and Myocardial Oxygen Consumption in the Isolated Heart115
Evidence that neural mechanisms do not have important effects on cerebral blood flow.115
Ca2+ regulation of mechanical properties of striated muscle. Mechanistic studies using extraction and replacement of regulatory proteins.115
Mechanisms of pHi recovery after global ischemia in the perfused heart.115
Endothelial expression of thrombomodulin is reversibly regulated by fluid shear stress.115
alpha-Adrenoceptor attenuation of the coronary vascular response to severe exercise in the conscious dog.115
Local Regulation of Vascular Cross Section during Changes in Femoral Arterial Blood Flow in Dogs115
Stimulation of Ca++ binding and ATPase activity of dog cardiac myofibrils by AR-L 115BS, a novel cardiotonic agent.115
Measurements of disordered flows distal to subtotal vascular stenoses in the thoracic aortas of dogs.115
Differences Between Left and Right Ventricular Chamber Geometry Affect Cardiac Vulnerability to Electric Shocks115
Enhanced Ca 2+ -Activated Na + -Ca 2+ Exchange Activity in Canine Pacing-Induced Heart Failure115
Dual effect of serotonin on growth of bovine pulmonary artery smooth muscle cells in culture.115
Transient depolarization and spontaneous voltage fluctuations in isolated single cells from guinea pig ventricles. Calcium-mediated membrane potential fluctuations.115
Regulation of Cytokine-Induced Nitric Oxide Synthesis by Asymmetric Dimethylarginine115
Synergistic Modulation of ATP-Sensitive K + Currents by Protein Kinase C and Adenosine115
Angiotensin II Activates pp60 c- src in Vascular Smooth Muscle Cells115
Differential impairment of vasodilator responsiveness of peripheral resistance and conduit vessels in humans with atherosclerosis.115
Cyclosporine Attenuates Pressure-Overload Hypertrophy in Mice While Enhancing Susceptibility to Decompensation and Heart Failure115
Protein Kinase D Is a Novel Mediator of Cardiac Troponin I Phosphorylation and Regulates Myofilament Function115
Bone Morphogenetic Protein 4 Promotes Pulmonary Vascular Remodeling in Hypoxic Pulmonary Hypertension115
β-Catenin Downregulation Is Required for Adaptive Cardiac Remodeling115
Prevention of Cardiac Hypertrophy by Atorvastatin in a Transgenic Rabbit Model of Human Hypertrophic Cardiomyopathy115
Effect of Epinephrine and Norepinephrine on Coronary Circulation114
Instantaneous Dimensional Changes of the Left Ventricle in Dogs114
Molecular Basis of Electrocardiographic ST-Segment Elevation114
Transmural distribution of myocardial blood flow during systole in the awake dog.114
Cardiac and Extracardiac Expression of Csx/Nkx2.5 Homeodomain Protein114
Inducible Expression of Egr-1–Dependent Genes114
Nongenomic, ER-Mediated Activation of Endothelial Nitric Oxide Synthase:114
Contribution of Intrarenal Generation of Prostaglandin to Autoregulation of Renal Blood Flow in the Dog114
Cardiac mitochondrial DNA polymerase-gamma is inhibited competitively and noncompetitively by phosphorylated zidovudine.114
Enhanced Na + Channel Intermediate Inactivation in Brugada Syndrome114
Characterization of angiotensin II receptor subtypes in rat heart.114
Contractile deactivation and uncoupling of crossbridges. Effects of 2,3-butanedione monoxime on mammalian myocardium.114
β 2 -Adrenergic Receptor Actions in Neonatal and Adult Rat Ventricular Myocytes114
Differential control of adrenal and renal sympathetic nerve activity during hemorrhagic hypotension in rats.114
Expression and Regulation of Adhesion Molecules in Cardiac Cells by Cytokines114
Application of Heated-Film Velocity and Shear Probes to Hemodynamic Studies114
Determinants of Vascular Smooth Muscle Cell Apoptosis After Balloon Angioplasty Injury114
Heteromultimeric assembly of human potassium channels. Molecular basis of a transient outward current?114
The Antiinflammatory Endothelial Tyrosine Kinase Tie2 Interacts With a Novel Nuclear Factor-κB Inhibitor ABIN-2114
Tyrosine Kinase Activity of Discoidin Domain Receptor 1 Is Necessary for Smooth Muscle Cell Migration and Matrix Metalloproteinase Expression114
Correlation between the response of the heart to sympathetic stimulation and the release of endogenous catecholamines into the coronary sinus of the dog.114
Peroxynitrite Inhibits Ca 2+ -Activated K + Channel Activity in Smooth Muscle of Human Coronary Arterioles114
Direct Effects of Smooth Muscle Relaxation and Contraction on In Vivo Human Brachial Artery Elastic Properties114
Impact of finite orifice size on proximal flow convergence. Implications for Doppler quantification of valvular regurgitation.114
Onset of Cardiac Function During Early Mouse Embryogenesis Coincides With Entry of Primitive Erythroblasts Into the Embryo Proper114
Thromboxane A 2 -Induced Inhibition of Voltage-Gated K + Channels and Pulmonary Vasoconstriction114
A Combined Morphological and Electrophysiological Study of the Atrioventricular Node of the Rabbit Heart114
Mitochondrial PKCε and Mitochondrial ATP-Sensitive K + Channel Copurify and Coreconstitute to Form a Functioning Signaling Module in Proteoliposomes114
Early Growth Response-1 Promotes Atherogenesis114
Regulation of Smooth Muscle Cell Proliferation by β-Catenin/T-Cell Factor Signaling Involves Modulation of Cyclin D1 and p21 Expression114
Human Pulmonary Valve Progenitor Cells Exhibit Endothelial/Mesenchymal Plasticity in Response to Vascular Endothelial Growth Factor-A and Transforming Growth Factor-β 2114
Ischemic Neoangiogenesis Enhanced by β 2 -Adrenergic Receptor Overexpression114
Troponin I isoform expression in human heart.113
Modulation of Cerebral Arteriolar Diameter by Intraluminal Flow and Pressure113
Delayed rectifier outward current and repolarization in human atrial myocytes.113
Collagen phenotypes during development and regression of myocardial hypertrophy in spontaneously hypertensive rats.113
Swelling-induced chloride-sensitive current in canine atrial cells revealed by whole-cell patch-clamp method.113
Systemic and Coronary Energetics in the Resting Unanesthetized Dog113
Regulation of the Brain’s Vascular Responses to Oxygen113
Non-Newtonian Rheology of Human Blood - Effect of Fibrinogen Deduced by "Subtraction"113
Interaction of Transmembrane Potentials in Canine Purkinje Fibers and at Purkinje Fiber-Muscle Junctions113
Both Donor and Recipient Origins of Smooth Muscle Cells in Vein Graft Atherosclerotic Lesions113
Reentry and Fibrillation in the Mouse Heart113
Selective dye and ionic permeability of gap junction channels formed by connexin45.113
Sensitization of dog and guinea pig heart myofilaments to Ca2+ activation and the inotropic effect of pimobendan: comparison with milrinone.113
Nitric oxide is a mediator of hypoxic coronary vasodilatation. Relation to adenosine and cyclooxygenase-derived metabolites.113
Modulation of severity of reperfusion stunning in the isolated rat heart by agents altering calcium flux at onset of reperfusion.113
Superoxide Is Involved in the Central Nervous System Activation and Sympathoexcitation of Myocardial Infarction–Induced Heart Failure113
Stereoselective actions of thiadiazinones on canine cardiac myocytes and myofilaments.113
Inhibition of Nuclear Factor-κB–Mediated Adhesion Molecule Expression in Human Endothelial Cells113
Inactivation of Voltage-Gated Cardiac K + Channels113
Platelet-activating factor contributes to the induction of nitric oxide synthase by bacterial lipopolysaccharide.113
A G/C Element Mediates Repression of the SM22α Promoter Within Phenotypically Modulated Smooth Muscle Cells in Experimental Atherosclerosis113
Remodeling of Cell-Cell and Cell–Extracellular Matrix Interactions at the Border Zone of Rat Myocardial Infarcts113
Overexpression of Tissue Inhibitor of Matrix Metalloproteinase-1 Inhibits Vascular Smooth Muscle Cell Functions In Vitro and In Vivo113
Roles of the Two Active Sites of Somatic Angiotensin-Converting Enzyme in the Cleavage of Angiotensin I and Bradykinin113
Differences in cardiac calcium release channel (ryanodine receptor) expression in myocardium from patients with end-stage heart failure caused by ischemic versus dilated cardiomyopathy.113
Triglyceride-Rich Lipoproteins Prime Aortic Endothelium for an Enhanced Inflammatory Response to Tumor Necrosis Factor-α113
Chromosome 1q21.1 Contiguous Gene Deletion Is Associated With Congenital Heart Disease113
Defective Lung Vascular Development and Fatal Respiratory Distress in Endothelial NO Synthase-Deficient Mice113
Cellular Mechanisms of Altered Contractility in the Hypertrophied Heart113
Molecular Coupling of a Ca 2+ -Activated K + Channel to L-Type Ca 2+ Channels via α-Actinin2113
Dobutamine-Stress Magnetic Resonance Microimaging in Mice113
Apoptosis During Cardiovascular Development112
The Adenylyl Cyclases as Integrators of Transmembrane Signal Transduction112
Microvascular pressures and resistances in the left ventricular subepicardium and subendocardium.112
Release of Adenosine from Anoxic Hearts112
Effect of sympathetic denervation on smooth muscle cell proliferation in the growing rabbit ear artery.112
A proposal linking clearance of circulating lipoproteins to tissue metabolic activity as a basis for understanding atherogenesis.112
Baroreflex control of the cutaneous active vasodilator system in humans.112
Regulation of Ca2+ channels by cAMP and cGMP in vascular smooth muscle cells.112
Local cerebral blood volume response to carbon dioxide in man.112
Activated Protein Kinase C Isoforms Target to Cardiomyocyte Caveolae112
Evidence for a renal alpha-adrenergic receptor inhibiting renin release.112
Rate of Vasoconstrictor Prostanoids Released by Endothelial Cells Depends on Cyclooxygenase-2 Expression and Prostaglandin I Synthase Activity112
Effects of duration and severity of arterial hypertension and cardiac hypertrophy on coronary vasodilator reserve.112
Hypertension, bradycardia, and pulmonary edema in the conscious rabbit after brainstem lesions coinciding with the A1 group of catecholamine neurons.112
Role of Protein Kinase C in Mitochondrial K ATP Channel–Mediated Protection Against Ca 2+ Overload Injury in Rat Myocardium112
Profound spatial heterogeneity of coronary reserve. Discordance between patterns of resting and maximal myocardial blood flow.112
Novel Role of ARF6 in Vascular Endothelial Growth Factor–Induced Signaling and Angiogenesis112
Increased vascular catecholamine sensitivity and alpha-adrenergic receptor affinity in female and estrogen-treated male rats.112
Absence of a lateral border zone of intermediate creatine phosphokinase depletion surrounding a central infarct 24 hours after acute coronary occlusion in the dog.112
Calcium- and Protein Kinase C–Dependent Activation of the Tyrosine Kinase PYK2 by Angiotensin II in Vascular Smooth Muscle112
Increased Expression of Axl Tyrosine Kinase After Vascular Injury and Regulation by G Protein–Coupled Receptor Agonists in Rats112
Differential Expression of Ion Channel Transcripts in Atrial Muscle and Sinoatrial Node in Rabbit112
Tumor Necrosis Factor-α Induces Early-Onset Endothelial Adhesivity by Protein Kinase Cζ–Dependent Activation of Intercellular Adhesion Molecule-1112
Novel NAD(P)H Oxidase Inhibitor Suppresses Angioplasty-Induced Superoxide and Neointimal Hyperplasia of Rat Carotid Artery112
Epicardial coronary artery responses to acetylcholine are impaired in hypertensive patients.112
Cooperative Interactions Between RB and p53 Regulate Cell Proliferation, Cell Senescence, and Apoptosis in Human Vascular Smooth Muscle Cells From Atherosclerotic Plaques112
The Dual-Specificity Phosphatase MKP-1 Limits the Cardiac Hypertrophic Response In Vitro and In Vivo112
Knockout Mice for Pharmacological Screening112
Mouse Model of a Familial Hypertrophic Cardiomyopathy Mutation in α-Tropomyosin Manifests Cardiac Dysfunction112
A Mutant Tropomyosin That Causes Hypertrophic Cardiomyopathy Is Expressed In Vivo and Associated With an Increased Calcium Sensitivity112
Demonstration of Selective Protein Kinase C–Dependent Activation of Src and Lck Tyrosine Kinases During Ischemic Preconditioning in Conscious Rabbits112
Regulation of the Transient Outward K + Current by Ca 2+ /Calmodulin-Dependent Protein Kinases II in Human Atrial Myocytes112
Regulation of eNOS Expression in Brain Endothelial Cells by Perinuclear EP 3 Receptors112
Myocardin Enhances Smad3-Mediated Transforming Growth Factor-β 1 Signaling in a CArG Box-Independent Manner112
Isometric Time-Tension Relationships as an Index of Myocardial Contractility111
Formation of the Atrioventricular Septal Structures in the Normal Mouse111
Beta-Receptor Activity in Aorta111
Dispersion and Attenuation of Small Artificial Pressure Waves in the Canine Aorta111
Inhibition of sympathetic vasoconstriction is a major principle of vasodilation by nitric oxide in vivo.111
Relationship between Sodium Intake and Norepinephrine Storage during the Development of Experimental Hypertension111
Force and velocity of sarcomere shortening in trabeculae from rat heart. Effects of temperature.111
Myocardial Presynaptic and Postsynaptic Autonomic Dysfunction in Hypertrophic Cardiomyopathy111
Angiotensin II-induced mitogenesis of spontaneously hypertensive rat-derived cultured smooth muscle cells is dependent on autocrine production of transforming growth factor-beta.111
Platelet-Derived Growth Factor D Induces Cardiac Fibrosis and Proliferation of Vascular Smooth Muscle Cells in Heart-Specific Transgenic Mice111
Cerebral Ischemia and Reactive Hyperemia111
Inducible Nitric Oxide Synthase Deficiency Protects the Heart From Systolic Overload–Induced Ventricular Hypertrophy and Congestive Heart Failure111
Cardiac Overexpression of Monocyte Chemoattractant Protein-1 in Transgenic Mice Prevents Cardiac Dysfunction and Remodeling After Myocardial Infarction111
Influence of ribose, adenosine, and "AICAR" on the rate of myocardial adenosine triphosphate synthesis during reperfusion after coronary artery occlusion in the dog.111
Evidence in Favor of a Calcium-Sensing Receptor in Arterial Endothelial Cells111
Sphingosylphosphorylcholine Is a Novel Messenger for Rho-Kinase–Mediated Ca 2+ Sensitization in the Bovine Cerebral Artery111
Cardiovascular Performance of Alaska Sled Dogs during Exercise110
Characterization of cardiac sarcoplasmic reticulum dysfunction during short-term, normothermic, global ischemia.110
Vasomotor Responses in the Human Arm During Leg Exercise110
Apoptosis (Programmed Cell Death) in Arteries of the Neonatal Lamb110
Estimating cardiac transmembrane activation and recovery times from unipolar and bipolar extracellular electrograms: a simulation study.110
Role of veins and cerebral venous pressure in disruption of the blood-brain barrier.110
Increased protein kinase C and isozyme redistribution in pressure-overload cardiac hypertrophy in the rat.110
Characteristics of Single Aortic and Right Subclavian Baroreceptor Fiber Activity in Rabbits with Chronic Renal Hypertension110
Effects of ischemia on rat myocardial function and metabolism in diabetes.110
Propagation of Impulses across the Purkinje Fiber-Muscle Junctions in the Dog Heart110
Direct Preconditioning of Cardiac Myocytes via Opioid Receptors and K ATP Channels110
Role of the Cerebellum and the Vestibular Apparatus in Regulation of Orthostatic Reflexes in the Cat110
Ca 2+ and Inositol 1,4,5-Trisphosphate–Mediated Signaling Across the Myoendothelial Junction110
Acute respiratory acidosis decreases left ventricular contractility but increases cardiac output in dogs.110
Intact vesicles of canine cardiac sarcolemma: evidence from vectorial properties of Na+, K+-ATPase.110
Enhanced renal prostaglandin production in the dog. I. Effects on renal function.110
Increased Ventricular Preload Is Compensated by Myocyte Proliferation in Normal and Hypoplastic Fetal Chick Left Ventricle110
Rat dilated cardiomyopathy after autoimmune giant cell myocarditis.110
Calcium Signaling in Endothelial Cells Involves Activation of Tyrosine Kinases and Leads to Activation of Mitogen-Activated Protein Kinases110
Use of Radioiodinated Fatty Acid for Photoscans of the Heart110
Correlation dimension of heartbeat intervals is reduced in conscious pigs by myocardial ischemia.110
NFATc3 and NFATc4 Are Required for Cardiac Development and Mitochondrial Function110
Cytoskeletal features of rat aortic cells during development. An electron microscopic, immunohistochemical, and biochemical study.110
Notch Ligand Delta-Like 1 Is Essential for Postnatal Arteriogenesis110
Cytoskeletal damage during myocardial ischemia: changes in vinculin immunofluorescence staining during total in vitro ischemia in canine heart.110
Precordial and epicardial surface potentials during Myocardial ischemia in the pig. A theoretical and experimental analysis of the TQ and ST segments.110
Cardiovascular effects of calcitonin gene-related peptides I and II in man.110
Phasic right coronary artery blood flow in conscious dogs with normal and elevated right ventricular pressures.110
Electrophysiological Basis of Arrhythmogenicity of QT/T Alternans in the Long-QT Syndrome110
Increased thromboxane biosynthesis during coronary thrombolysis. Evidence that platelet activation and thromboxane A2 modulate the response to tissue-type plasminogen activator in vivo.110
Activation of Extracellular Signal–Regulated Kinases (ERK1/2) by Angiotensin II Is Dependent on c-Src in Vascular Smooth Muscle Cells110
c-Jun N-Terminal Kinase Activation Mediates Downregulation of Connexin43 in Cardiomyocytes110
Reduction of Cardiac Tyrosine Hydroxylase Activity in Experimental Congestive Heart Failure110
Short-Term Treatment With Ranolazine Improves Mechanical Efficiency in Dogs With Chronic Heart Failure110
Platelet-derived growth factor suppresses and fibroblast growth factor enhances cytokine-induced production of nitric oxide by cultured smooth muscle cells. Effects on cell proliferation.110
Cardiac Myosin Light Chain-2110
Renal and systemic hemodynamic responses to intravenous infusion of leukotriene C4 in the rat.110
Depressed Heart Rate Variability and Arterial Baroreflex in Conscious Transgenic Mice With Overexpression of Cardiac G 110
Oxidized Phospholipids Stimulate Angiogenesis Via Autocrine Mechanisms, Implicating a Novel Role for Lipid Oxidation in the Evolution of Atherosclerotic Lesions110
Nonlinearities of the human carotid baroreceptor-cardiac reflex.109
Interactions of granulocytes with the lungs.109
Development Gone Awry109
Conduction of the Cardiac Impulse109
Permeability of the Alveolar Membrane to Solutes109
Cellular Mechanism of Calcium-Mediated Triggered Activity in the Heart109
Connexin Expression and Turnover109
Some Characteristics of Transmembrane Potentials of AV Nodal Cells during Propagation of Premature Beats109
Interstitial Fluid Pressure: III. Its Effect on Resistance to Tissue Fluid Mobility109
In Vivo Analysis of Adrenergic Receptor Activity of Dobutamine109
Protein Kinase A Does Not Alter Economy of Force Maintenance in Skinned Rat Cardiac Trabeculae109
Estimation of Stroke Volume in the Dog by a Pulse Contour Method109
Human Cardiovascular Adjustments to Rapid Changes in Skin Temperature during Exercise109
Influence of the Direction of the Atrial Wave Front on A-V Nodal Transmission in Isolated Hearts of Rabbits109
Effects of aging on mechanics and composition of cerebral arterioles in rats.109
Acute impairment of endothelium-dependent relaxations to aggregating platelets following reperfusion injury in canine coronary arteries.109
Phosphatidylinositol 3-Kinase Is Required for Insulin-Like Growth Factor-I–Induced Vascular Smooth Muscle Cell Proliferation and Migration109
Quantitative regional determination of morphometric indices of the total and perfused capillary network in the rat brain.109
Recovery from Cardiac Bypass and Elective Cardiac Arrest109
Role of cardiac ATP-regulated potassium channels in differential responses of endocardial and epicardial cells to ischemia.109
Mobilization of Bone Marrow–Derived Cells Enhances the Angiogenic Response to Hypoxia Without Transdifferentiation Into Endothelial Cells109
Apoptosis of Cardiac Myocytes in Gsα Transgenic Mice109
Role of Respiratory Motor Output in Within-Breath Modulation of Muscle Sympathetic Nerve Activity in Humans109
Proto-oncogene expression in porcine myocardium subjected to ischemia and reperfusion.109
Dose-dependent inhibition of stretch-induced arrhythmias by gadolinium in isolated canine ventricles. Evidence for a unique mode of antiarrhythmic action.109
Attenuation of the Slow Component of Delayed Rectification, Action Potential Prolongation, and Triggered Activity in Mice Expressing a Dominant-Negative Kv2 α Subunit109
Angiotensin II increases spontaneous contractile frequency and stimulates calcium current in cultured neonatal rat heart myocytes: insights into the underlying biochemical mechanisms.109
Electrophysiological Properties of Cardiac Muscle in the Anterior Mitral Valve Leaflet and the Adjacent Atrium in the Dog109
Differential Response to Na + Channel Blockade, β-Adrenergic Stimulation, and Rapid Pacing in a Cellular Model Mimicking the SCN5A and HERG Defects Present in the Lo109
Long-Term and Sustained COMP-Ang1 Induces Long-Lasting Vascular Enlargement and Enhanced Blood Flow109
Proteomics of the Heart108
Effects of Dopamine in Man108
The Interplay of Coronary Vascular Resistance and Myocardial Compression in Regulating Coronary Flow108
Protection by beta-blocking agents against free radical-mediated sarcolemmal lipid peroxidation.108
Vascular Remodeling Versus Vasoconstriction in Chronic Hypoxic Pulmonary Hypertension108
Different electrophysiological responses of canine endocardium and epicardium to combined hyperkalemia, hypoxia, and acidosis.108
Pumping ability of the hypertrophying left ventricle of the spontaneously hypertensive rat.108
Determinants of Antiarrhythmic Drug Action108
Enhanced Na + -Ca 2+ Exchange in the Infarcted Heart108
Influence of the lonic Environment on Spontaneous Electrical and Mechanical Activity of the Rat Portal Vein108
Protein Kinase C Activates ATP-Sensitive K + Current in Human and Rabbit Ventricular Myocytes108
Reperfusion-Induced Translocation of δPKC to Cardiac Mitochondria Prevents Pyruvate Dehydrogenase Reactivation108
Effects of substrates on tissue metabolic changes in the isolated rat heart during underperfusion and on release of lactate dehydrogenase and arrhythmias during reperfusion.108
Increased Nitric Oxide Synthase Activity and Expression in the Human Uterine Artery During Pregnancy108
Depressed function of a ouabain-sensitive sodium-potassium pump in blood vessels from renal hypertensive dogs.108
Vasomodulation by Skeletal Muscle–Derived Nitric Oxide Requires α-Syntrophin–Mediated Sarcolemmal Localization of Neuronal Nitric Oxide Synthase108
Simulated Ischemia in Flow-Adapted Endothelial Cells Leads to Generation of Reactive Oxygen Species and Cell Signaling108
Tumor Necrosis Factor-α–Induced AT 1 Receptor Upregulation Enhances Angiotensin II–Mediated Cardiac Fibroblast Responses That Favor Fibrosis108
Partition of Blood Flow to the Cutaneous and Muscular Beds of the Forearm at Rest and during Leg Exercise in Normal Subjects and in Patients with Heart Failure108
Transient Exposure to Hydrogen Peroxide Causes an Increase in Mitochondria-Derived Superoxide As a Result of Sustained Alteration in L-Type Ca 2+ Channel Function in108
Diverse Mechanisms of Myocardial p38 Mitogen-Activated Protein Kinase Activation108
Alk3/Bmpr1a Receptor Is Required for Development of the Atrioventricular Canal Into Valves and Annulus Fibrosus108
Effects of unilateral stellectomy upon cardiac performance during exercise in dogs.107
A comparison of volume conductor and source geometry effects on body surface and epicardial potentials.107
Cdc42 Regulates the Restoration of Endothelial Barrier Function107
Effect of Hemorrhage on the Cardiac Output and Distribution in the Rat107
Myofilament Ca2+ sensitivity in intact versus skinned rat ventricular muscle.107
Human Heart Generates Complement Proteins That Are Upregulated and Activated After Myocardial Infarction107
Spread of Electrical Activity Through the Wall of the Ventricle107
Excess membrane cholesterol alters calcium movements, cytosolic calcium levels, and membrane fluidity in arterial smooth muscle cells.107
Reduction by adenosine of the isoproterenol-induced increase in cyclic adenosine 3',5'-monophosphate formation and glycogen phosphorylase activity in rat heart muscle.107
Beta-adrenergic receptor stimulation increases unloaded shortening velocity of skinned single ventricular myocytes from rats.107
Endothelium-dependent modulation of cGMP levels and intrinsic smooth muscle tone in isolated bovine intrapulmonary artery and vein.107
Determinants of Notch-3 Receptor Expression and Signaling in Vascular Smooth Muscle Cells107
Renal adrenoceptor mediation of antinatriuretic and renin secretion responses to low frequency renal nerve stimulation in the dog.107
Direct Inhibition of Expressed Cardiac L-Type Ca 2+ Channels by S -Nitrosothiol Nitric Oxide Donors107
Transforming Growth Factor β Receptor Endoglin Is Expressed in Cardiac Fibroblasts and Modulates Profibrogenic Actions of Angiotensin II107
Activation of Cardiac Tissue by Extracellular Electrical Shocks107
Reduced production of cGMP underlies the loss of endothelium-dependent relaxations in the canine basilar artery after subarachnoid hemorrhage.107
Contribution of Sodium Channel Mutations to Bradycardia and Sinus Node Dysfunction in LQT3 Families107
Impulse Propagation in Synthetic Strands of Neonatal Cardiac Myocytes With Genetically Reduced Levels of Connexin43107
Effect of exercise on the relationship between myocardial blood flow and systolic wall thickening in dogs with acute coronary stenosis.107
Vascular Inflammation Is Negatively Autoregulated by Interaction Between CCAAT/Enhancer-Binding Protein-δ and Peroxisome Proliferator-Activated Receptor-γ107
Critical Role of Cyclin D1 Nuclear Import in Cardiomyocyte Proliferation107
Dismantling of Cadherin-Mediated Cell-Cell Contacts Modulates Smooth Muscle Cell Proliferation107
Direct Evidence for Endothelial Vascular Endothelial Growth Factor Receptor-1 Function in Nitric Oxide–Mediated Angiogenesis107
In Vivo Collagen Turnover Following Experimental Balloon Angioplasty Injury and the Role of Matrix Metalloproteinases107
Insulin-like Growth Factor-1 but Not Growth Hormone Augments Mammalian Myocardial Contractility by Sensitizing the Myofilament to Ca 2+ Through a Wortmannin-Sensitiv107
xIAP Induces Cell-Cycle Arrest and Activates Nuclear Factor-κB106
Oxygen Sensing by Primary Cardiac Fibroblasts106
Activation of Histone Deacetylase 2 by Inducible Heat Shock Protein 70 in Cardiac Hypertrophy106
Cell Type–Specific Angiotensin II–Evoked Signal Transduction Pathways106
β 2 -Adrenergic and Several Other G Protein–Coupled Receptors in Human Atrial Membranes Activate Both G s and G i106
The relationship among cardiac pacemakers. Overdrive suppression.106
Neurogenic vasodilation of cat cerebral arteries.106
Activation of Adenyl Cyclase by Glucagon in Cat and Human Heart106
In vivo electrophysiological effects of lidocaine in canine acute myocardial infarction.106
Vascular endothelium-leukocyte interaction; sticking shear force in venules.106
Dyssynchronous Ca 2+ Sparks in Myocytes From Infarcted Hearts106
Increased capillary hydraulic conductivity induced by atrial natriuretic peptide.106
The effects of variations in conductivity and geometrical parameters on the electrocardiogram, using an eccentric spheres model.106
Evidence and quantification of the vasopressin arterial pressure control system in the dog.106
A Flow-Activated Chloride-Selective Membrane Current in Vascular Endothelial Cells106
Effects of sympathetic stimulation and changes in arterial pressure on segmental resistance of cerebral vessels in rabbits and cats.106
Molecular Mechanisms of Neutrophil-Endothelial Cell Adhesion Induced by Redox Imbalance106
Mechanism by which cyclic adenosine 3':5'-monophosphate-dependent protein kinase stimulates calcium transport in cardiac sarcoplasmic reticulum.106
Comparison of Sphingosine 1-Phosphate–Induced Intracellular Signaling Pathways in Vascular Smooth Muscles106
Impaired canine coronary vasodilator response to acetylcholine and bradykinin after occlusion-reperfusion.106
Role of Endothelium-Derived Nitric Oxide in the Regulation of Cardiac Oxygen Metabolism106
Essential Role for Vascular Gelatinase Activity in Relaxin-Induced Renal Vasodilation, Hyperfiltration, and Reduced Myogenic Reactivity of Small Arteries106
Acidosis Inhibits Endothelial Cell Apoptosis and Function and Induces Basic Fibroblast Growth Factor and Vascular Endothelial Growth Factor Expression106
ADP Acting on P2Y 13 Receptors Is a Negative Feedback Pathway for ATP Release From Human Red Blood Cells106
Adenosine Receptor Activation Induces Vascular Endothelial Growth Factor in Human Retinal Endothelial Cells106
Diabetes Downregulates Large-Conductance Ca 2+ -Activated Potassium β1 Channel Subunit in Retinal Arteriolar Smooth Muscle106
Flow-induced trauma to blood cells.105
Ionic currents during hypoxia in voltage-clamped cat ventricular muscle.105
Coronary pressure-function and steady-state pressure-flow relations during autoregulation in the unanesthetized dog.105
Effects of Angiotensin II and Some Analogues on Vascular Permeability in the Rabbit105
Mechanisms of Delayed Electrical Uncoupling Induced by Ischemic Preconditioning105
Cofibrins and Fibrin-Intermediates as Indicators of Thrombin Activity in Vivo105
Reduction of maximal coronary vasodilator capacity in conscious dogs with severe right ventricular hypertrophy.105
Histamine and interstitial Pulmonary Edema in the Dog105
Intrarenal Hemodynamics in Glycerol-Induced Myohemoglobinuric Acute Renal Failure in the Rat105
Origins of Serum Semicarbazide-Sensitive Amine Oxidase105
Participation of Central Noradrenergic Neurons in Arterial Baroreceptor Reflexes in the Rabbit: A STUDY WITH INTRACISTERNALLY ADMINISTERED 6-HYDROXYDOPAMINE105
Lymph and pulmonary response to isobaric reduction in plasma oncotic pressure in baboons.105
Adrenergic Modulation of Ultrarapid Delayed Rectifier K + Current in Human Atrial Myocytes105
Central Command Increases Muscle Sympathetic Nerve Activity During Intense Intermittent Isometric Exercise in Humans105
Functional Significance of Prorenin Internalization in the Rat Heart105
Whole-cell and single-channel calcium currents of isolated smooth muscle cells from saphenous vein.105
Differential sensitivity of arteriolar alpha 1- and alpha 2-adrenoceptor constriction to metabolic inhibition during rat skeletal muscle contraction.105
High Blood Pressure Upregulates Arterial L-Type Ca 2+ Channels105
Conduction disturbances caused by high current density electric fields.105
The Ultrastructure of the Heart in Systole and Diastole105
Vascular Matrix Metalloproteinase-2–Dependent Cleavage of Calcitonin Gene-Related Peptide Promotes Vasoconstriction105
Simulation of high-resolution QRS complex using a ventricular model with a fractal conduction system. Effects of ischemia on high-frequency QRS potentials.105
Assessment of smooth muscle contribution to descending thoracic aortic elastic mechanics in conscious dogs.105
Static linear and nonlinear elastic properties of normal and arterialized venous tissue in dog and man.105
Myocardial Mechanics and Collagen Structure in the Osteogenesis Imperfecta Murine ( oim )105
Overexpression of Hyaluronan in the Tunica Media Promotes the Development of Atherosclerosis105
Regulation of angiotensin II receptors on ventricular myocytes after myocardial infarction in rats.105
Lipid-Lowering Agents105
all- trans -Retinoic Acid Increases Nitric Oxide Synthesis by Endothelial Cells105
VEGF 165 Expressed by a Replication-Deficient Recombinant Adenovirus Vector Induces Angiogenesis In Vivo105
Cardiac-Specific IGF-1 Expression Attenuates Dilated Cardiomyopathy in Tropomodulin-Overexpressing Transgenic Mice105
Evidence That Phospholipid Oxidation Products and/or Platelet-Activating Factor Play an Important Role in Early Atherogenesis105
Downregulation of Endothelin-1 by Farnesoid X Receptor in Vascular Endothelial Cells105
Crucial Role of the CCL2/CCR2 Axis in Neointimal Hyperplasia After Arterial Injury in Hyperlipidemic Mice Involves Early Monocyte Recruitment and CCL2 Presentation on Platelets105
Selective Downregulation of VEGF-A 165 , VEGF-R 1 , and Decreased Capillary Density in Patients With Dilative but Not Ischemic Car105
Mechanism of complement activation after coronary artery occlusion: evidence that myocardial ischemia in dogs causes release of constituents of myocardial subcellular origin that complex with human C1105
Gut Microbial Associations to Plasma Metabolites Linked to Cardiovascular Phenotypes and Risk105
Cardiac Myosin Binding Protein C104
The renal kallikrein-kinin system.104
Importance of Atrial Compliance in Cardiac Performance104
Targeting Rho in Cardiovascular Disease104
Action potential propagation in a thick strand of cardiac muscle.104
Automatic activity in depolarized guinea pig ventricular myocardium. Characteristics and mechanisms.104
SM22α Modulates Vascular Smooth Muscle Cell Phenotype During Atherogenesis104
Segmental alpha-receptor-mediated vasoconstriction in the canine coronary circulation.104
Mechanisms underlying the development of ventricular fibrillation during early myocardial ischemia.104
Antiarrhythmic drug action. Blockade of the inward sodium current.104
Sodium channel block produces opposite electrophysiological effects in canine ventricular epicardium and endocardium.104
Aortic Arteriosclerosis in the Dog After Localized Aortic X-lrradiation104
Differential Response of Large and Small Coronary Arteries to Nitroglycerin and Angiotensin104
Reducation of the Utilization of the Heart by Left Heart Bypass104
Suppression of Angiotensin-Converting Enzyme Expression and Activity by Shear Stress104
Intracellular alkalinization induced by bradykinin sustains activation of the constitutive nitric oxide synthase in endothelial cells.104
Mechanical and morphological properties of arterial resistance vessels in young and old spontaneously hypertensive rats.104
Mitochondria-Derived Reactive Oxygen Species Dilate Cerebral Arteries by Activating Ca 2+ Sparks104
Compartmentation of Cyclic Nucleotide Signaling in the Heart104
Heparin regulates smooth muscle S phase entry in the injured rat carotid artery.104
Role of endothelium-derived prostaglandins in hypoxia-elicited arteriolar dilation in rat skeletal muscle.104
Vasoactive Potential of the B 1 Bradykinin Receptor in Normotension and Hypertension104
Functional Properties of Mouse Connexin30.2 Expressed in the Conduction System of the Heart104
Intimal injury and regrowth in the rabbit aorta; medial smooth muscle cells as a source of neointima.104
Durations of Transmembrane Action Potentials and Functional Refractory Periods of Canine False Tendon and Ventricular Myocardium:104
Cellular and ventricular contractile dysfunction in experimental canine mitral regurgitation.104
I f Current and Spontaneous Activity in Mouse Embryonic Ventricular Myocytes104
Quantification of collateral resistance in acute and chronic experimental coronary occlusion in the dog.104
Postnatal maturation of excitation-contraction coupling in rat ventricle in relation to the subcellular localization and surface density of 1,4-dihydropyridine and ryanodine receptors.104
Protein Kinase A–Mediated Acceleration of the Stretch Activation Response in Murine Skinned Myocardium Is Eliminated by Ablation of cMyBP-C104
Biochemical Correlates of Cardiac Hypertrophy104
The Role of the Multidrug Resistance Protein-1 in Modulation of Endothelial Cell Oxidative Stress104
The relationship between myocardial blood flow and contraction by myocardial layer in the canine left ventricle during ischemia.104
Mitogen-Activated Protein/Extracellular Signal–Regulated Kinase Inhibition Attenuates Angiotensin II–Mediated Signaling and Contraction in Spontaneously Hypertensive Rat Vascular Smooth Muscle Cells104
Functional Consequences of Sulfhydryl Modification in the Pore-Forming Subunits of Cardiovascular Ca 2+ and Na + Channels104
Phospholipase C ε Modulates β-Adrenergic Receptor– Dependent Cardiac Contraction and Inhibits Cardiac Hypertrophy104
Expression and Function of Endothelial Ca 2+ -Activated K + Channels in Human Mesenteric Artery104
Low-Voltage-Activated (T-Type) Calcium Channels Control Proliferation of Human Pulmonary Artery Myocytes104
Proteomic Analysis of Pharmacological Preconditioning104
Activation of Adenosine A 1 Receptor Attenuates Cardiac Hypertrophy and Prevents Heart Failure in Murine Left Ventricular Pressure-Overload Model104
Effects of Epinephrine on Lipid Partition and Metabolism in the Rabbit103
Renal Pressor System and Neurogenic Control of Arterial Pressure103
Transthoracic Ventricular Defibrillation with Triangular and Trapezoidal Waveforms103
Heterocellular Contact at the Myoendothelial Junction Influences Gap Junction Organization103
Vascular Effects of Hypertonic Solutions103
Specialized Conducting Fibers in the Interatrial Band103
Antibody and Complement in Transplant Vasculopathy103
Ca2+ uptake by cardiac sarcoplasmic reticulum from patients with idiopathic dilated cardiomyopathy.103
Disappearance of bradykinin in the renal circulation of dogs. Effects of kininase inhibition.103
Microscopic conduction in cultured strands of neonatal rat heart cells measured with voltage-sensitive dyes.103
Identification and characterization of the high affinity vascular angiotensin II receptor in rat mesenteric artery.103
In vivo 31P nuclear magnetic resonance measurements in canine heart using a catheter-coil.103
Histochemical and fatigue characteristics of conditioned canine latissimus dorsi muscle.103
Fibroblast Growth Factor Receptor-1 Is Essential for In Vitro Cardiomyocyte Development103
Increased Myocardial Oxygen Consumption and Contractile State Associated with Increased Heart Rate in Dogs103
Pulsatile flow and pressure in human systemic arteries. Studies in man and in a multibranched model of the human systemic arterial tree.103
Transmural right ventricular blood flow during acute pulmonary artery hypertension in the sedated dog. Evidence for subendocardial ischemia despite residual vasodilator reserve.103
Evaluation of left ventricular contractile performance utilizing end-systolic pressure-volume relationships in conscious dogs.103
Decreased Expression of Voltage- and Ca 2+ -Activated K + Channels in Coronary Smooth Muscle During Aging103
AKAP-Mediated Targeting of Protein Kinase A Regulates Contractility in Cardiac Myocytes103
Influence of Duration of Cholesterol Feeding on Esterification of Fatty Acids by Cell-Free Preparation of Pigeon Aorta103
Novel Mechanism of Action for Hydralazine103
High-Resolution Optical Mapping of the Right Bundle Branch in Connexin40 Knockout Mice Reveals Slow Conduction in the Specialized Conduction System103
In vitro study on contribution of oxidative metabolism of isolated rabbit heart mitochondria to myocardial reperfusion injury.103
Cardiomyocyte Degeneration With Calpain Deficiency Reveals a Critical Role in Protein Homeostasis103
Platelet Phagocytosis and Processing of β-Amyloid Precursor Protein as a Mechanism of Macrophage Activation in Atherosclerosis103
Induction of Vascular Endothelial Growth Factor in Balloon-Injured Baboon Arteries103
Regulation of Vascular Connexin43 Gene Expression by Mechanical Loads102
Adrenergic Stimulation of Renin Secretion in the Isolated Perfused Rat Kidney102
Nitrendipine binding in congestive heart failure due to myocardial infarction.102
Effects of Cyclic AMP, Sympathomimetic Amines, and Adrenergic Receptor Antagonists on Renin Secretion102
Differential effects of antihypertensive drug therapy on vascular smooth muscle cell hypertrophy, hyperploidy, and hyperplasia in the spontaneously hypertensive rat.102
Effects of a Digitalis Glycoside on Coronary and Systemic Dynamics in Conscious Dogs102
Acute hypertension after the local injection of kainic acid into the nucleus tractus solitarii of rats.102
Reflex chronotropic and inotropic effects of calcium channel-blocking agents in conscious dogs. Diltiazem, verapamil, and nifedipine compared.102
Magnetic determination of the relationship between the S-T segment shift and the injury current produced by coronary artery occlusion.102
Basic Fibroblast Growth Factor Increases Collateral Blood Flow in Rats With Femoral Arterial Ligation102
Hypoxia-Induced Endothelial Proliferation Requires Both mTORC1 and mTORC2102
The effects of shortening on myoplasmic calcium concentration and on the action potential in mammalian ventricular muscle.102
Regulation of Connexin43 Protein Complexes by Intracellular Acidification102
Intracoronary alpha 2-adrenergic receptor blockade attenuates ischemia in conscious dogs during exercise.102
Ca 2+ Release Mechanisms, Ca 2+ Sparks, and Local Control of Excitation-Contraction Coupling in Normal Heart Muscle102
GFP-FRNK Disrupts Focal Adhesions and Induces Anoikis in Neonatal Rat Ventricular Myocytes102
Transmission of intrathoracic pressure to the intracranial space during cardiopulmonary resuscitation in dogs.102
Blockade of ATP-sensitive potassium channels increases infarct size but does not prevent preconditioning in rabbit hearts.102
Generation of Functional Cardiomyocytes From Adult Mouse Spermatogonial Stem Cells102
Subcellular Creatine Kinase Alterations102
Vascular Smooth Muscle α v β 3 Integrin Mediates Arteriolar Vasodilation in Response to RGD Peptides102
Lipid alterations in isolated, working rat hearts during ischemia and reperfusion: its relation to myocardial damage.102
Contribution of cAMP-phosphodiesterase inhibition and sensitization of the contractile proteins for calcium to the inotropic effect of pimobendan in the failing human myocardium.102
Angiotensin II–Induced Growth Responses in Isolated Adult Rat Hearts102
Compensatory Hyperfunction of the Heart and Cardiac Insufficiency101
Conditional Transgene Expression in the Heart101
Dual Role of Reactive Oxygen Species in Vascular Growth101
Flow-mediated dilatation of the basilar artery in vivo.101
Enhancement of rabbit cardiac sodium channels by beta-adrenergic stimulation.101
Adrenergic Receptor Activity in the Coronary Arteries of the Unanesthetized Dog101
Estimation of the Residual Volume of the Ventricle of the Dog's Heart by Two Indicator Dilution Technics101
Transmural gradients in ventricular tissue metabolites produced by stopping coronary blood flow in the dog.101
Pressures in the Pial Arterial Microcirculation of the Cat during Changes in Systemic Arterial Blood Pressure101
Differences in transient outward currents of feline endocardial and epicardial myocytes.101
Oxidized low density lipoproteins potentiate vasoconstrictions to various agonists by direct interaction with vascular smooth muscle.101
Relaxation of rabbit ventricular muscle by Na-Ca exchange and sarcoplasmic reticulum calcium pump. Ryanodine and voltage sensitivity.101
Ras/Erk Signaling Is Essential for Activation of Protein Synthesis by Gq Protein-Coupled Receptor Agonists in Adult Cardiomyocytes101
Activation of Mitochondrial K ATP Channel Elicits Late Preconditioning Against Myocardial Infarction via Protein Kinase C Signaling Pathway101
Influence of Brief Vagal and Stellate Nerve Stimulation on Pacemaker Activity and Conduction within the Atrioventricular Conduction System of the Dog101
Alteration of NMDA NR 1 Receptors Within the Paraventricular Nucleus of Hypothalamus in Rats With Heart Failure101
Transgenic Modeling of a Cardiac Troponin I Mutation Linked to Familial Hypertrophic Cardiomyopathy101
Specific block of the anti-ischemic actions of cromakalim by sodium 5-hydroxydecanoate.101
Akt Mediates the Cross-Talk Between β-Adrenergic and Insulin Receptors in Neonatal Cardiomyocytes101
Leukemia Inhibitory Factor, a Potent Cardiac Hypertrophic Cytokine, Activates the JAK/STAT Pathway in Rat Cardiomyocytes101
Functional coronary microvascular injury evident as increased permeability due to brief ischemia and reperfusion.101
Normal Development of the Outflow Tract in the Rat101
Left Ventricular Filling and Diastolic Pressure-Volume Relations in the Conscious Dog101
Ischemic Preconditioning Activates MAPKAPK2 in the Isolated Rabbit Heart101
Velocity of the creatine kinase reaction decreases in postischemic myocardium: a 31P-NMR magnetization transfer study of the isolated ferret heart.101
Novel Mechanism of Endothelial Nitric Oxide Synthase Activation Mediated by Caveolae Internalization in Endothelial Cells101
The Spread of Sinus Activation During Potassium Administration100
Local Postural Vasomotor Reflexes Arising from the Limb Veins100
Sex differences in peripheral vascular adrenergic receptors.100
Evidence for Fusion Between Cardiac and Skeletal Muscle Cells100
Congruence of total and perfused capillary network in rat brains.100
Ionic basis for the antagonism between adenosine and isoproterenol on isolated mammalian ventricular myocytes.100
In-Vitro Studies of Myocardial Asynchrony and Regional Hypoxia100
Directional Difference of Conduction Velocity in the Cardiac Ventricular Syncytium Studied by Microelectrodes100
A model of psychosocial hypertension showing reversibility and progression of cardiovascular complications.100
Calmodulin modulation of single sarcoplasmic reticulum Ca2+-release channels from cardiac and skeletal muscle.100
Regulation of blood-brain barrier endothelial cells by nitric oxide.100
Communication between feed arteries and microvessels in hamster striated muscle: segmental vascular responses are functionally coordinated.100
Quantitative studies of microcirculatory structure and function. III. Microvascular hemodynamics of cat mesentery and rabbit omentum.100
Localization of Pacemaker Channels in Lipid Rafts Regulates Channel Kinetics100
Anisotropy of water diffusion in the myocardium of the rat.100
Rapid Inhibition of Vasoconstriction in Renal Afferent Arterioles by Aldosterone100
Behavior of genes directly injected into the rat heart in vivo.100
Role of resistance and exchange vessels in local microvascular control of skeletal muscle oxygenation in the dog.100
A Dominant-Negative p65 PAK Peptide Inhibits Angiogenesis100
Interaction of inhomogeneities of repolarization with anisotropic propagation in dog atria. A mechanism for both preventing and initiating reentry.100
Lesion Development and Response to Immunization Reveal a Complex Role for CD4 in Atherosclerosis100
Role of Phosphodiesterase 3 in NO/cGMP-Mediated Antiinflammatory Effects in Vascular Smooth Muscle Cells100
The Troponin C G159D Mutation Blunts Myofilament Desensitization Induced by Troponin I Ser23/24 Phosphorylation100
Overexpression of HAX-1 Protects Cardiac Myocytes From Apoptosis Through Caspase-9 Inhibition100
Importance of venodilatation in prevention of left ventricular dilatation after chronic large myocardial infarction in rats: a comparison of captopril and hydralazine.100
Alveolar Type 1 Cells Express the α2 Na,K-ATPase, Which Contributes to Lung Liquid Clearance100
Maximal upstroke velocity as an index of available sodium conductance. Comparison of maximal upstroke velocity and voltage clamp measurements of sodium current in rabbit Purkinje fibers.100
Proinflammatory Effects of Bacterial Recombinant Human C-Reactive Protein Are Caused by Contamination With Bacterial Products, Not by C-Reactive Protein Itself100
Oxidative Mediated Lipid Peroxidation Recapitulates Proarrhythmic Effects on Cardiac Sodium Channels100
Immunomodulator FTY720 Induces eNOS-Dependent Arterial Vasodilatation via the Lysophospholipid Receptor S1P 3100
BTEB2, a Krüppel-Like Transcription Factor, Regulates Expression of the SMemb/Nonmuscle Myosin Heavy Chain B (SMemb/NMHC-B) Gene100
Pulmonary Alveolar Blood Flow99
Aldosterone Upregulates Ca 2+ Current in Adult Rat Cardiomyocytes99
Calcium Requirements for Cardiac Myofibrillar Activation99
Vascular smooth muscle cell hypertrophy and hyperploidy in the Goldblatt hypertensive rat.99
Sensitivity of left ventricular end-systolic pressure-volume relation to type of loading intervention in dogs.99
Caveolin-1 Deficiency Increases Cerebral Ischemic Injury99
Quantitative ultrasonic characterization of the nature of atherosclerotic plaques in human aorta.99
Reevaluation of Oxidative Phosphorylation in Cardiac Mitochondria from Normal Animals and Animals in Heart Failure99
Effects of Catecholamines and Renal Nerve Stimulation on Renin Release in the Nonfilterlng Kidney99
Initial myocardial adjustments to brief periods of ischemia and reperfusion in the conscious dog.99
Role of Redox Signaling in the Autonomous Proliferative Response of Endothelial Cells to Hypoxia99
Cloning and Functional Expression of a Novel Cardiac Two-Pore Background K + Channel (cTBAK-1)99
Transport of 14 C-4-Cholesterol between Serum and Wall in the Perfused Dog Common Carotid Artery99
Crossbridge scheme and the kinetic constants of elementary steps deduced from chemically skinned papillary and trabecular muscles of the ferret.99
Heteromultimeric Kv1 Channels Contribute to Myogenic Control of Arterial Diameter99
Role of Ion Channels and Exchangers in Mechanical Stretch–Induced Cardiomyocyte Hypertrophy99
Intrinsic Myofilament Alterations Underlying the Decreased Contractility of Stunned Myocardium99
End-systolic pressure determines stroke volume from fixed end-diastolic volume in the isolated canine left ventricle under a constant contractile state.99
Feedback regulation of angiotensin converting enzyme activity and mRNA levels by angiotensin II.99
Neuropilin-1 Regulates Vascular Endothelial Growth Factor–Mediated Endothelial Permeability99
Myosin types in the human heart. An immunofluorescence study of normal and hypertrophied atrial and ventricular myocardium.99
Angiotensin II Type 2 Receptor Inhibits Vascular Endothelial Growth Factor–Induced Migration and In Vitro Tube Formation of Human Endothelial Cells99
The Architecture of the Heart in Systole and Diastole99
Protein Kinase C–Induced Changes in the Stoichiometry of ATP Binding Activate Cardiac ATP-Sensitive K + Channels99
Increased Expression of Ca 2+ -Sensitive K + Channels in the Cerebral Microcirculation of Genetically Hypertensive Rats99
Adeno-Associated Virus-Mediated Transduction of VEGF165 Improves Cardiac Tissue Viability and Functional Recovery After Permanent Coronary Occlusion in Conscious Dogs99
Expression of Coxsackievirus and Adenovirus Receptor in Hearts of Rats With Experimental Autoimmune Myocarditis99
Local Monocyte Chemoattractant Protein-1 Therapy Increases Collateral Artery Formation in Apolipoprotein E–Deficient Mice but Induces Systemic Monocytic CD11b Expression, Neointimal Formation, and Pla99
In Vivo and In Vitro Studies Support That a New Splicing Isoform of OLR1 Gene Is Protective Against Acute Myocardial Infarction99
c-Jun N-Terminal Kinases Mediate Reactivation of Akt and Cardiomyocyte Survival After Hypoxic Injury In Vitro and In Vivo99
Optimized Treatment of ST-Elevation Myocardial Infarction99
Discovery of Distinct Immune Phenotypes Using Machine Learning in Pulmonary Arterial Hypertension99
Smooth Muscle–Specific Expression of the Smooth Muscle Myosin Heavy Chain Gene in Transgenic Mice Requires 5′-Flanking and First Intronic DNA Sequence98
The Sarcoplasmic Reticulum and the Na + /Ca 2+ Exchanger Both Contribute to the Ca 2+ Transient98
Involvement of IsK-Associated K + Channel in Heart Rate Control of Repolarization in a Murine Engineered Model of Jervell and Lange-Nielsen Syndrome98
Program of Cell Survival Underlying Human and Experimental Hibernating Myocardium98
Nuclear Targeting of Akt Enhances Ventricular Function and Myocyte Contractility98
Hepatocyte Growth Factor Suppresses Vascular Endothelial Growth Factor-Induced Expression of Endothelial ICAM-1 and VCAM-1 by Inhibiting the Nuclear Factor-κB Pathway98
Myocardial Actions of Angiotensin98
The Metabolic Significance of the Malate-Aspartate Cycle in Heart.98
Pressure-Dependent Heterogeneity of Renal Cortical Blood Flow in Dogs98
Biphasic Vasoconstriction of the Rabbit Ear Artery98
Measurement of Flow in Single Blood Vessels Including Cardiac Output by Local Thermodilution98
Stem Cells and the Regeneration of the Aging Cardiovascular System98
Gap junction messenger RNA expression by vascular wall cells.98
Ionic Remodeling in the Heart98
Thyroxine-induced redistribution of isoenzymes of rabbit ventricular myosin.98
Angiotensin-Converting Enzyme Inhibitors Downregulate Tissue Factor Synthesis in Monocytes98
Hemodynamic responses of the sheep fetus to vasopressin infusion.98
Effects of extracellular potassium on ventricular automaticity and evidence for a pacemaker current in mammalian ventricular myocardium.98
Potent vasoconstriction mediated by endothelin ETB receptors in canine coronary arteries.98
A Redox-Based Mechanism for Cardioprotection Induced by Ischemic Preconditioning in Perfused Rat Heart98
Upper limit of cerebral blood flow autoregulation in experimental renovascular hypertension in the baboon.98
Dependence of hypoxic cellular calcium loading on Na(+)-Ca2+ exchange.98
Antiangiogenic Activity of the MDM2 Antagonist Nutlin-398
Fetal Liver-Sparing Cardiovascular Adaptations Linked to Mother’s Slimness and Diet98
Small Heat-Shock Protein Hsp20 Phosphorylation Inhibits β-Agonist-Induced Cardiac Apoptosis98
Mechanism of Norepinephrine Depletion in Experimental Heart Failure Produced by Aortic Constriction in the Guinea Pig98
Adrenomedullin as a Novel Antimigration Factor of Vascular Smooth Muscle Cells98
Oscillatory Flow Impedance in Electrical Analog of Arterial System:98
Estrogen Causes Dynamic Alterations in Endothelial Estrogen Receptor Expression98
Effects of III-IV linker mutations on human heart Na+ channel inactivation gating.98
Nitric Oxide Attenuates Neutrophil-Mediated Myocardial Contractile Dysfunction After Ischemia and Reperfusion98
Cell Composition, Replication, and Apoptosis in Atherosclerotic Plaques After 6 Months of Cholesterol Withdrawal98
Atorvastatin Restores Endothelial Function in Normocholesterolemic Smokers Independent of Changes in Low-Density Lipoprotein98
Exercise Improves Postischemic Cardiac Function in Males but Not Females98
Relationship between beta-adrenergic receptor numbers and physiological responses during experimental canine myocardial ischemia.98
Plasma Cholesteryl Esters Provided by Lecithin:Cholesterol Acyltransferase and Acyl-Coenzyme A:Cholesterol Acyltransferase 2 Have Opposite Atherosclerotic Potential98
Nuclear Factor-κB Regulates Induction of Apoptosis and Inhibitor of Apoptosis Protein-1 Expression in Vascular Smooth Muscle Cells98
Angiotensin II Stimulates c-Jun NH 2 -Terminal Kinase in Cultured Cardiac Myocytes of Neonatal Rats98
Protein Kinase Cα Negatively Regulates Systolic and Diastolic Function in Pathological Hypertrophy98
Brief Reviews: Magnesium in Heart Muscle97
Characteristics of left ventricular receptors with nonmedullated vagal afferents in cats.97
Estimating the Functional Capabilities of Sarcoplasmic Reticulum in Cardiac Muscle97
Role of Protein Kinase C in Ischemic Preconditioning: Player or Spectator?97
Inhibition by carotid baroreflex of exercise-induced increases in arterial pressure.97
Vascular reactivity of isolated perfused kidneys from male and female spontaneously hypertensive rats.97
High Incidence of Cardiac Malformations in Connexin40-Deficient Mice97
Proteomic Approaches to Analyze the Dynamic Relationships Between Nucleocytoplasmic Protein Glycosylation and Phosphorylation97
Integrated Ca 2+ Signaling Between Smooth Muscle and Endothelium of Resistance Vessels97
Cardiac Septation97
Nuclear Receptor Signaling in the Control of Cholesterol Homeostasis97
Mechanism for Flow Distribution in Normal and Ischemic Myocardium during Increased Ventricular Preload in the Dog97
Tubulovascular Nitric Oxide Crosstalk97
Acidosis-Induced Coronary Arteriolar Dilation Is Mediated by ATP-Sensitive Potassium Channels in Vascular Smooth Muscle97
Reevaluation of Arterial Constitutive Relations: A FINITE-DEFORMATION APPROACH97
Ablation of Cardiac Myosin-Binding Protein-C Accelerates Stretch Activation in Murine Skinned Myocardium97
Hydrodynamic Forces in Dissecting Aneurysms97
Relationship of aortic wall and baroreceptor properties during development in normotensive and spontaneously hypertensive rats.97
Inotropic response to hypothermia and the temperature-dependence of ryanodine action in isolated rabbit and rat ventricular muscle: implications for excitation-contraction coupling.97
High density lipoprotein reverses inhibitory effect of oxidized low density lipoprotein on endothelium-dependent arterial relaxation.97
Regulation of Ventricular Contraction by the Carotid Sinus97
Shear Stress–Mediated Chromatin Remodeling Provides Molecular Basis for Flow-Dependent Regulation of Gene Expression97
Changes in renin, water balance, and sodium balance during development of high blood pressure in genetically hypertensive rats.97
Alterations in Myofilament Function Contribute to Left Ventricular Dysfunction in Pigs Early After Myocardial Infarction97
Overexpression of Urokinase by Macrophages or Deficiency of Plasminogen Activator Inhibitor Type 1 Causes Cardiac Fibrosis in Mice97
Effect of right ventricular pressure on the end-diastolic left ventricular pressure-volume relationship before and after chronic right ventricular pressure overload in dogs without pericardia.97
Optical measurements of transmembrane potential changes during electric field stimulation of ventricular cells.97
Very-Long-Chain Acyl-Coenzyme A Dehydrogenase Deficiency in Mice97
De Novo Expression of Killer Immunoglobulin-Like Receptors and Signaling Proteins Regulates the Cytotoxic Function of CD4 T Cells in Acute Coronary Syndromes97
Determinants of Atherosclerosis Susceptibility in the C3H and C57BL/6 Mouse Model97
Experimental Diabetes Is Associated With Functional Activation of Protein Kinase Cε and Phosphorylation of Troponin I in the Heart, Which Are Prevented by Angiotensin II Receptor Blockade97
Reduced Expression of Vascular Endothelial Growth Factor Paralleled With the Increased Angiostatin Expression Resulting From the Upregulated Activities of Matrix Metalloproteinase-2 and -9 in Human Ty97
Stem Cells as a Source of Regenerative Cardiomyocytes96
Regulation of cardiac contractile proteins. Correlations between physiology and biochemistry.96
Characteristics of action potentials of hypertrophied myocardium from rats with renal hypertension.96
The Mechanically Active Domain of Titin in Cardiac Muscle96
Selective inhibition of endothelium-dependent vasodilator capacity by Escherichia coli endotoxemia.96
Protective Role of Increased Myocardial Glycogen Stores in Cardiac Anoxia in the Rat96
Use of Random Excitation and Spectral Analysis in the Study of Frequency-Dependent Parameters of the Cardiovascular System96
Regional myocardial blood flow during acute myocardial infarction in the conscious dog.96
Conductances and Selective Permeability of Connexin43 Gap Junction Channels Examined in Neonatal Rat Heart Cells96
Regulation of Protein Kinase B and 4E-BP1 by Oxidative Stress in Cardiac Myocytes96
Functional Characterization of Connexin43 Mutations Found in Patients With Oculodentodigital Dysplasia96
Intramural reentry as a mechanism of ventricular tachycardia during evolving canine myocardial infarction.96
Site and Mechanism of Uptake of 3 H-/-Norepinephrine by Isolated Perfused Rat Lungs96
Epoxyeicosatrienoic Acids Are Released to Mediate Shear Stress–Dependent Hyperpolarization of Arteriolar Smooth Muscle96
Pressure Overload Induces Severe Hypertrophy in Mice Treated With Cyclosporine, an Inhibitor of Calcineurin96
Fluid Shear Stress Induces Lipocalin-Type Prostaglandin D 2 Synthase Expression in Vascular Endothelial Cells96
Angiogenic Effects of Adrenomedullin in Ischemia and Tumor Growth96
Correlation of plasma serotonin changes with platelet aggregation in an in vivo dog model of spontaneous occlusive coronary thrombus formation.96
Mechanical Strain Tightly Controls Fibroblast Growth Factor-2 Release From Cultured Human Vascular Smooth Muscle Cells96
Nitric Oxide–Independent Relaxations to Acetylcholine and A23187 Involve Different Routes of Heterocellular Communication96
Functional and Structural Assessment of Intercellular Communication96
Molecular Analysis of a Binding Site for Quinidine in a Human Cardiac Delayed Rectifier K + Channel96
The Antianginal Agent Trimetazidine Does Not Exert Its Functional Benefit via Inhibition of Mitochondrial Long-Chain 3-Ketoacyl Coenzyme A Thiolase96
Functional Reconstitution of Endothelial Nitric Oxide Synthase Reveals the Importance of Serine 1179 in Endothelium-Dependent Vasomotion96
De Novo Synthesis of Cyclooxygenase-1 Counteracts the Suppression of Platelet Thromboxane Biosynthesis by Aspirin96
Expression of Endothelin-1, Endothelin-3, Endothelin-Converting Enzyme-1, and Endothelin-A and Endothelin-B Receptor mRNA After Angioplasty-Induced Neointimal Formation in the Rat96
Ischemia of the dog heart induces the appearance of a cardiac mRNA coding for a protein with migration characteristics similar to heat-shock/stress protein 71.96
Nonsynchronous accumulation of alpha-skeletal actin and beta-myosin heavy chain mRNAs during early stages of pressure-overload--induced cardiac hypertrophy demonstrated by in situ hybridization.96
Role of Nuclear Ca 2+ /Calmodulin-Stimulated Phosphodiesterase 1A in Vascular Smooth Muscle Cell Growth and Survival96
Effects of D-4F on Vasodilation and Vessel Wall Thickness in Hypercholesterolemic LDL Receptor–Null and LDL Receptor/Apolipoprotein A-I Double-Knockout Mice on Western Diet96
Myocardial reactive hyperemia.95
Arterial Ultrastructure Influences Transport of Locally Delivered Drugs95
Afterpotentials and triggered activity in hypertrophied myocardium from rats with renal hypertension.95
Longitudinal Tethering of Arteries in Dogs95
Functional and hemodynamic adaptation to progressive renal ablation.95
Supernormal Excitability and Conduction in the His-Purkinje System of the Dog95
Participation of Central Noradrenergic Neurons in Arterial Baroreceptor Reflexes in the Rabbit95
Chronic labile hypertension produced by lesions of the nucleus tractus solitarii in the cat.95
Developmental Remodeling of the Internal Elastic Lamina of Rabbit Arteries95
Lipoproteins and the inhibitory effect of human endothelial cells on platelet function.95
Regional cardiac prostaglandin release during myocardial ischemia in anesthetized dogs.95
In Vivo Survival and Function of Transplanted Rat Cardiomyocytes95
The heart as a target organ in systemic allergic reactions: comparison of cardiac analphylaxis in vivo and in vitro.95
Developmental changes in the ultrastructure and sarcomere shortening of the isolated rabbit ventricular myocyte.95
Potentiation of Endothelium-Dependent Relaxation by Epoxyeicosatrienoic Acids95
A comparison of calcium currents in rat and guinea pig single ventricular cells.95
Angiotensin-Converting Enzyme Is Involved in Outside-In Signaling in Endothelial Cells95
Radiolabeled acetate as a tracer of myocardial tricarboxylic acid cycle flux.95
Temporally and Spatially Coordinated Expression of Cell Cycle Regulatory Factors After Angioplasty95
Firing characteristics of single-fiber carotid sinus baroreceptors.95
Angiotensin II–Induced Ca 2+ Influx in Renal Afferent and Efferent Arterioles95
Aldose Reductase Is an Obligatory Mediator of the Late Phase of Ischemic Preconditioning95
Complement Activation in Angiotensin II–Induced Organ Damage95
Cardiac Troponin I Gene Knockout95
Angiotensin II–Induced Leukocyte Adhesion on Human Coronary Endothelial Cells Is Mediated by E-Selectin95
Effects of adrenergic amines on electrophysiological properties and automaticity of neonatal and adult canine Purkinje fibers: evidence for alpha- and beta-adrenergic actions.95
G Protein βγ Subunits Stimulate p114RhoGEF, a Guanine Nucleotide Exchange Factor for RhoA and Rac195
Phosphorylation of Troponin I Controls Cardiac Twitch Dynamics95
The Brain Renin-Angiotensin System Contributes to the Hypertension in Mice Containing Both the Human Renin and Human Angiotensinogen Transgenes95
Sphingosine-1 Phosphate Prevents Monocyte/Endothelial Interactions in Type 1 Diabetic NOD Mice Through Activation of the S1P1 Receptor95
Adenosine A 1 Receptor Induced Delayed Preconditioning in Rabbits95
Potential fields generated by oblique dipole layers modeling excitation wavefronts in the anisotropic myocardium. Comparison with potential fields elicited by paced dog hearts in a volume conductor.95
Endothelin-1, via ET A Receptor and Independently of Transforming Growth Factor-β, Increases the Connective Tissue Growth Factor in Vascular Smooth Muscle Cells95
Type 5 Adenylyl Cyclase Disruption Alters Not Only Sympathetic But Also Parasympathetic and Calcium-Mediated Cardiac Regulation95
p38 Kinase Is a Negative Regulator of Angiotensin II Signal Transduction in Vascular Smooth Muscle Cells95
Type 2 Diabetes and Hypertension95
Prostaglandins and the Kidney94
The Contribution of Blood Momentum to Left Ventricular Ejection in the Dog94
Localization of angiotensinogen messenger RNA in rat aorta.94
Comparison of Sympathetic Nerve Activity in Normotensive and Hypertensive Subjects94
Role of prostacyclin in the preservation of ischemic myocardial tissue in the perfused cat heart.94
5-hydroxytryptamine and neurotransmitter release in canine blood vessels. Inhibition by low and augmentation by high concentrations.94
Tumor Necrosis Factor-α Induces a Biphasic Effect on Myocardial Contractility in Conscious Dogs94
The effects on atrial electrophysiology and structure of surgically induced right atrial enlargement in dogs.94
Alterations in canine myocardial excitability during ischemia.94
Altered Urinary Kallikrein Excretion in Rats with Hypertension94
Use-dependent block and use-dependent unblock of the delayed rectifier K+ current by almokalant in rabbit ventricular myocytes.94
Overexpression of VEGF-C Causes Transient Lymphatic Hyperplasia but Not Increased Lymphangiogenesis in Regenerating Skin94
Nafazatrom-induced salvage of ischemic myocardium in anesthetized dogs is mediated through inhibition of neutrophil function.94
Mechanism of beneficial effect of beta-adrenergic blockade on exercise-induced myocardial ischemia in conscious dogs.94
EphA4-Mediated Rho Activation via Vsm-RhoGEF Expressed Specifically in Vascular Smooth Muscle Cells94
Respiratory Sinus Arrhythmia94
Quantitative changes in the capillary bed during developing, peak, and stabilized cardiac hypertrophy in the spontaneously hypertensive rat.94
Loss of Pentameric Symmetry in C-Reactive Protein Induces Interleukin-8 Secretion Through Peroxynitrite Signaling in Human Neutrophils94
Evidence for Ca 2+ Activation and Inactivation Sites on the Luminal Side of the Cardiac Ryanodine Receptor Complex94
Spatial Changes in Transmembrane Potential During Extracellular Electrical Shocks in Cultured Monolayers of Neonatal Rat Ventricular Myocytes94
Two Components of Delayed Rectifier Current in Canine Atrium and Ventricle94
Antibodies to the ADP/ATP carrier, an autoantigen in myocarditis and dilated cardiomyopathy, penetrate into myocardial cells and disturb energy metabolism in vivo.94
Essential Role of Developmentally Activated Hypoxia-Inducible Factor 1α for Cardiac Morphogenesis and Function94
Coexistence of beta 1- and beta 2-adrenoceptors in human right atrium. Direct identification by (+/-)-[125I]iodocyanopindolol binding.94
Targeted Disruption of the Mouse Sod I Gene Makes the Hearts Vulnerable to Ischemic Reperfusion Injury94
Bone Sialoprotein Mediates Human Endothelial Cell Attachment and Migration and Promotes Angiogenesis94
Increasing Survival of Ischemic Tissue by Targeting CD4794
Expression and Function of Recombinant Endothelial Nitric Oxide Synthase Gene in Canine Basilar Artery94
Low Concentration of Oxidized Low-Density Lipoprotein and Lysophosphatidylcholine Upregulate Constitutive Nitric Oxide Synthase mRNA Expression in Bovine Aortic Endothelial Cells94
Superoxide dismutase conjugated to polyethylene glycol provides sustained protection against myocardial ischemia/reperfusion injury in canine heart.94
Nitric Oxide Inhibits Capacitative Cation Influx in Human Platelets by Promoting Sarcoplasmic/Endoplasmic Reticulum Ca 2+ -ATPase–Dependent Refilling of Ca 94
Extracellular action of adenosine and the antagonism by aminophylline on the atrioventricular conduction of isolated perfused guinea pig and rat hearts.94
Comparison of Unitary Displacements and Forces Between 2 Cardiac Myosin Isoforms by the Optical Trap Technique94
Transgenic Overexpression of Locally Acting Insulin-Like Growth Factor-1 Inhibits Ubiquitin-Mediated Muscle Atrophy in Chronic Left-Ventricular Dysfunction94
Sympathetic Nerve Sprouting, Electrical Remodeling, and Increased Vulnerability to Ventricular Fibrillation in Hypercholesterolemic Rabbits94
Spatial Microstimuli in Endothelial Mechanosignaling93
Renin in Rats with Spontaneous Hypertension93
Control of myocardial oxygen tension by sympathetic coronary vasoconstriction in the dog.93
Reflex regulation of sympathetic activity in the spontaneously hypertensive rat.93
Reflex Venoconstriction and Capacity Vessel Pressure-Volume Relationships in Dogs93
Prostaglandins and the control of blood flow in the canine myocardium.93
Relation between transcardiac and transthoracic current during defibrillation in humans.93
Mechanism of the Effects of Furosemide on Renin Secretion in Anesthetized Dogs93
The Preconditioning Phenomenon93
Heterogeneous microvascular coronary alpha-adrenergic vasoconstriction.93
Heterogeneity of the hypoxic state in perfused rat heart.93
Angiotensin degradation products mediate endothelium-dependent dilation of rabbit brain arterioles.93
Disposal of Human Chylomicrons Administered Intravenously in Ischemic Heart Disease and Essential Hyperlipemia93
Multi-Tasking RGS Proteins in the Heart93
Virtual Electrode–Induced Reexcitation93
Intracellular Ca 2+ Increases the Mitochondrial NADH Concentration During Elevated Work in Intact Cardiac Muscle93
Apoptosis of Rat Vascular Smooth Muscle Cells Is Regulated by p53-Dependent and -Independent Pathways93
Vesicular Trafficking of Tyrosine Kinase Receptors and Associated Proteins in the Regulation of Signaling and Vascular Function93
Epicardial/Mesothelial Cell Line Retains Vasculogenic Potential of Embryonic Epicardium93
Chronic Treatment With Allopurinol Boosts Survival and Cardiac Contractility in Murine Postischemic Cardiomyopathy93
Hibernating Myocardium Retains Metabolic and Contractile Reserve Despite Regional Reductions in Flow, Function, and Oxygen Consumption at Rest93
Microvascular Responses to Inhibition of Nitric Oxide Production93
Homeobox A9 Transcriptionally Regulates the EphB4 Receptor to Modulate Endothelial Cell Migration and Tube Formation93
Role of nitric oxide, muscarinic receptors, and the ATP-sensitive K+ channel in mediating the effects of acetylcholine to mimic preconditioning in dogs.93
Failure of Calcineurin Inhibitors to Prevent Pressure-Overload Left Ventricular Hypertrophy in Rats93
Hetero-Domain Interactions as a Mechanism for the Regulation of Connexin Channels93
Transmural activations and stimulus potentials in three-dimensional anisotropic canine myocardium.93
Shear Stress Regulates Forward and Reverse Planar Cell Polarity of Vascular Endothelium In Vivo and In Vitro93
Sphingosine 1-Phosphate Transactivates the Platelet-Derived Growth Factor β Receptor and Epidermal Growth Factor Receptor in Vascular Smooth Muscle Cells93
A dihydropyridine (Bay k 8644) that enhances calcium currents in guinea pig and calf myocardial cells. A new type of positive inotropic agent.93
Identification of Prostaglandin E2 Receptor Subtype 2 As a Receptor Activated by OxPAPC93
Proarrhythmic Consequences of a KCNQ1 AKAP-Binding Domain Mutation93
Effects of Delayed Rectifier Current Blockade by E-4031 on Impulse Generation in Single Sinoatrial Nodal Myocytes of the Rabbit93
Heart Defects in Connexin43-Deficient Mice93
Determinants of a protective effect of glucose and insulin on the ischemic myocardium. Effects on contractile function, diastolic compliance, metabolism, and ultrastructure during ischemia and reperfu93
In vivo observation of subendocardial microvessels of the beating porcine heart using a needle-probe videomicroscope with a CCD camera.93
Changes in myofibrillar content and Mg-ATPase activity in ventricular tissues from patients with heart failure caused by coronary artery disease, cardiomyopathy, or mitral valve insufficiency.93
Role of Cardiac Myosin Binding Protein C in Sustaining Left Ventricular Systolic Stiffening93
Growth of capillaries in skeletal and cardiac muscle.92
Sympathetic Control of Cerebral Blood Flow in Dogs92
Potential Role for Kv3.1b Channels as Oxygen Sensors92
Effects of quinidine on action potentials and ionic currents in isolated canine ventricular myocytes.92
A comparison of aortic baroreceptor discharge in normotensive and spontaneously hypertensive rats.92
Hearts from diabetic rats are more resistant to in vitro ischemia: possible role of altered Ca2+ metabolism.92
Vasa vasorum in atherosclerotic coronary arteries: responses to vasoactive stimuli and regression of atherosclerosis.92
Immunohistochemical delineation of the conduction system. II: The atrioventricular node and Purkinje fibers.92
Distribution of Stresses and of Strain-Energy Density through the Wall Thickness in a Canine Aortic Segment92
Electroaugmentation of Ventricular Performance and Oxygen Consumption by Repetitive Application of Paired Electrical Stimuli92
Relationship of Pericardial to Pleural Pressure During Quiet Respiration and Cardiac Tamponade92
Correlation of the glycoside response, the force staircase, and the action potential configuration in the neonatal rat heart.92
Vascular Endothelial–Cadherin Tyrosine Phosphorylation in Angiogenic and Quiescent Adult Tissues92
Morphology of electrophysiologically identified junctions between Purkinje fibers and ventricular muscle in rabbit and pig hearts.92
Stimulation of renal sympathetic activity by static contraction: evidence for mechanoreceptor-induced reflexes from skeletal muscle.92
Effects of Changes in Blood Flow Rate on Cell Death and Cell Proliferation in Carotid Arteries of Immature Rabbits92
Intracellular Localization and Functional Effects of P 21 -Activated Kinase-1 (Pak1) in Cardiac Myocytes92
Inhibition and Rapid Recovery of Ca 2+ Current During Ca 2+ Release From Sarcoplasmic Reticulum in Guinea Pig Ventricular Myocytes92
Opposing Effects of Reactive Oxygen Species and Cholesterol on Endothelial Nitric Oxide Synthase and Endothelial Cell Caveolae92
Elastin and collagen accumulation in rabbit ascending aorta and pulmonary trunk during postnatal growth. Correlation of cellular synthetic response with medial tension.92
Remodeling of Gap Junctional Coupling in Hypertrophied Right Ventricles of Rats With Monocrotaline-Induced Pulmonary Hypertension92
Altered Expression of Tropomodulin in Cardiomyocytes Disrupts the Sarcomeric Structure of Myofibrils92
Endothelial dysfunction in response to psychosocial stress in monkeys.92
Electrophysiological effects of amphiphiles on canine purkinje fibers. Implications for dysrhythmia secondary to ischemia.92
Phosphatidylinositol 3-Kinase–Akt Pathway Plays a Critical Role in Early Cardiomyogenesis by Regulating Canonical Wnt Signaling92
Role of abnormally high transmural pressure in the permselectivity defect of glomerular capillary wall: a study in early passive Heymann nephritis.92
Excitation Sequences of the Atrial Septum and the AV Node in Isolated Hearts of the Dog and Rabbit92
Reperfusion-Activated Akt Kinase Prevents Apoptosis in Transgenic Mouse Hearts Overexpressing Insulin-Like Growth Factor-192
Protease-Activated Receptor-1–Mediated DNA Synthesis in Cardiac Fibroblast Is via Epidermal Growth Factor Receptor Transactivation92
Role of Angiotensin II in Activation of the JAK/STAT Pathway Induced by Acute Pressure Overload in the Rat Heart92
Maternal Hypercholesterolemia Enhances Atherogenesis in Normocholesterolemic Rabbits, Which Is Inhibited by Antioxidant or Lipid-Lowering Intervention During Pregnancy92
Detection of acute myocardial infarction in closed-chest dogs by analysis of regional two-dimensional echocardiographic gray-level distributions.92
An Osteopontin–NADPH Oxidase Signaling Cascade Promotes Pro–Matrix Metalloproteinase 9 Activation in Aortic Mesenchymal Cells92
Molecular Imaging of Atherosclerotic Plaques Using a Human Antibody Against the Extra-Domain B of Fibronectin92
Membrane Potential Fluctuations Resulting From Submembrane Ca 2+ Releases in Rabbit Sinoatrial Nodal Cells Impart an Exponential Phase to the Late Diastolic Depolari92
Adolescent Feline Heart Contains a Population of Small, Proliferative Ventricular Myocytes With Immature Physiological Properties92
Mechanism of Ca++ antagonist-induced vasodilation. Intracellular actions.91
Inhibition of adrenergic vasoconstriction by endothelial cell shear stress.91
Muscle stiffness determined from canine left ventricular pressure-volume curves.91
The mechanism of alpha-adrenergic activation of the dog coronary artery.91
The Mechanism of Atrioventricular Conduction91
Principal Factor Waveforms of the Thoracic QRS Complex91
Changes in extracellular and intracellular pH in ischemic rabbit papillary muscle.91
Changes in intracellular calcium during mechanical alternans in isolated ferret ventricular muscle.91
Diverse Origin of Intimal Cells91
Nonuniformity of Endothelial Constitutive Nitric Oxide Synthase Distribution in Cardiac Endothelium91
Optical Mapping Reveals That Repolarization Spreads Anisotropically and Is Guided by Fiber Orientation in Guinea Pig Hearts91
Morphometry of exercise-induced right ventricular hypertrophy in the rat.91
Activation of Mitogen-Activated Protein Kinase in Porcine Carotid Arteries91
NAD(P)H Oxidase Inhibition Attenuates Neuronal Chronotropic Actions of Angiotensin II91
Prior receptor occupancy as a determinant of the pressor activity of infused angiotensin II in the rat.91
Effect of Hemorrhagic Shock on the Reactivity of Resistance and Capacitance Vessels and on Capillary Filtration Transfer in Cat Skeletal Muscle91
Role of the JAK/STAT Pathway in Rat Carotid Artery Remodeling After Vascular Injury91
EVEC, a Novel Epidermal Growth Factor–Like Repeat-Containing Protein Upregulated in Embryonic and Diseased Adult Vasculature91
Impaired KCNQ1–KCNE1 and Phosphatidylinositol-4,5-Bisphosphate Interaction Underlies the Long QT Syndrome91
Increased Cyclooxygenase-2 Expression and Prostaglandin-Mediated Dilation in Coronary Arterioles of Patients With Diabetes Mellitus91
Left and right ventricular pump function and consequences of having two pumps in one heart. A study on the isolated cat heart.91
Effects of acidic fibroblast growth factor on normal and ischemic myocardium.91
Role of the left atrium in adaptation of the heart to chronic mitral regurgitation in conscious dogs.91
Enhanced Functional Gap Junction Neoformation by Protein Kinase A–Dependent and Epac-Dependent Signals Downstream of cAMP in Cardiac Myocytes91
Regression of Hypertrophied Rat Pulmonary Arteries in Organ Culture Is Associated With Suppression of Proteolytic Activity, Inhibition of Tenascin-C, and Smooth Muscle Cell Apoptosis91
PPARα Activators Inhibit Vascular Endothelial Growth Factor Receptor-2 Expression by Repressing Sp1-Dependent DNA Binding and Transactivation91
Insulin-Like Growth Factor-1 Attenuates the Detrimental Impact of Nonocclusive Coronary Artery Constriction on the Heart91
Central neural mechanisms of the cerebral ischemic response. Characterization, effect of brainstem and cranial nerve transections, and simulation by electrical stimulation of restricted regions of med91
Wavebreak Formation During Ventricular Fibrillation in the Isolated, Regionally Ischemic Pig Heart91
On the Molecular Nature of the Lidocaine Receptor of Cardiac Na + Channels91
Effects of thyroid hormone on alpha-actin and myosin heavy chain gene expression in cardiac and skeletal muscles of the rat: measurement of mRNA content using synthetic oligonucleotide probes.91
A 1 or A 3 Adenosine Receptors Induce Late Preconditioning Against Infarction in Conscious Rabbits by Different Mechanisms91
Akt Controls Vascular Smooth Muscle Cell Proliferation In Vitro and In Vivo by Delaying G1/S Exit91
Reversal of Chronic Molecular and Cellular Abnormalities Due to Heart Failure by Passive Mechanical Ventricular Containment91
Overexpression of FK506-Binding Protein FKBP12.6 in Cardiomyocytes Reduces Ryanodine Receptor–Mediated Ca 2+ Leak From the Sarcoplasmic Reticulum and Increases Contr91
Human Apolipoprotein A-II Enrichment Displaces Paraoxonase From HDL and Impairs Its Antioxidant Properties91
Upregulation of Alveolar Epithelial Active Na + Transport Is Dependent on β 2 -Adrenergic Receptor Signaling91
Relation between glycolysis and calcium homeostasis in postischemic myocardium.90
Resonance. The missing phenomenon in hemodynamics.90
αB-Crystallin Modulates Protein Aggregation of Abnormal Desmin90
Tissue-Destructive Macrophages in Giant Cell Arteritis90
Alpha-skeletal actin is associated with increased contractility in the mouse heart.90
Effect of intrarenal angiotensin II blockade on renal function in conscious dogs.90
The effects of lysophosphatidylcholine, a toxic metabolite of ischemia, on the components of cardiac excitability in sheep Purkinje fibers.90
Hypercapnic Acidosis Activates K ATP Channels in Vascular Smooth Muscles90
Effect of adenosine on atrioventricular conduction. I: Site and characterization of adenosine action in the guinea pig atrioventricular node.90
Evidence for an adenosine receptor on the surface of dog coronary myocytes.90
Vascular and adrenal receptors for atrial natriuretic factor in the rat.90
Mechanisms of augmented segment shortening in nonischemic areas during acute ischemia of the canine left ventricle.90
The effects of nifedipine on acute experimental myocardial ischemia and infarction in dogs.90
Cardiac Norepinephrine Stores and the Contractile State of Heart Muscle90
Relationship between Fatty-Acid Composition of Platelets and Platelet Aggregation in Rat and Man90
Coiled perimysial fibers of papillary muscle in rat heart: morphology, distribution, and changes in configuration.90
Paradoxical cAMP-Induced Lung Endothelial Hyperpermeability Revealed by Pseudomonas aeruginosa ExoY90
Aortic pulse wave velocity, elasticity, and composition in a nonhuman primate model of atherosclerosis.90
Comparison of the effects of increased myocardial oxygen consumption and adenosine on the coronary microvascular resistance.90
G Protein β3 Subunit 825T Allele and Enhanced Coronary Vasoconstriction on α 2 -Adrenoceptor Activation90
Alterations of myocardial blood flow associated with experimental canine left ventricular hypertrophy secondary to valvular aortic stenosis.90
Functional Reconstitution of Vascular Smooth Muscle Cells With cGMP-Dependent Protein Kinase I Isoforms90
Characterization of thrombin receptor expression during vascular lesion formation.90
Cellular Senescence Impairs Circadian Expression of Clock Genes In Vitro and In Vivo90
Endothelial Cells Secrete Triglyceride Lipase and Phospholipase Activities in Response to Cytokines as a Result of Endothelial Lipase90
Tie2 Receptor Expression Is Stimulated by Hypoxia and Proinflammatory Cytokines in Human Endothelial Cells90
Electrical Propagation in Synthetic Ventricular Myocyte Strands From Germline Connexin43 Knockout Mice90
Identification of Novel Interactions Between Domains of Myosin Binding Protein-C That Are Modulated by Hypertrophic Cardiomyopathy Missense Mutations90
Neointimal Smooth Muscle Cells Display a Proinflammatory Phenotype Resulting in Increased Leukocyte Recruitment Mediated by P-Selectin and Chemokines90
Myocardial alpha 1-adrenoceptors mediate positive inotropic effect and changes in phosphatidylinositol metabolism. Species differences in receptor distribution and the intracellular coupling process i90
Liver X Receptor Activation Controls Intracellular Cholesterol Trafficking and Esterification in Human Macrophages90
Differential Actions of PAR 2 and PAR 1 in Stimulating Human Endothelial Cell Exocytosis and Permeability90
Right ventricular preload recruitable stroke work, end-systolic pressure-volume, and dP/dtmax-end-diastolic volume relations compared as indexes of right ventricular contractile performance in conscio90
Endothelial Dysfunction and Hypertension in Rats Transduced With CYP4A2 Adenovirus90
Critical Roles for the Fas/Fas Ligand System in Postinfarction Ventricular Remodeling and Heart Failure90
Early Exercise Training Normalizes Myofilament Function and Attenuates Left Ventricular Pump Dysfunction in Mice With a Large Myocardial Infarction90
Nuclear miR-320 Mediates Diabetes-Induced Cardiac Dysfunction by Activating Transcription of Fatty Acid Metabolic Genes to Cause Lipotoxicity in the Heart90
Cholinergic mechanism in the large cat cerebral artery.90
Automatic Recognition of Electrocardiographic Waves by Digital Computer90
Increased sheep lung vascular permeability caused by histamine.90
Estimation of Coronary Blood Flow by Washout of Diffusible Indicators90
Neutralization of endogenous tumor necrosis factor ameliorates the severity of myosin-induced myocarditis.90
Hypertrophy, Pathology, and Molecular Markers of Cardiac Pathogenesis90
Critical Review of Recent Work on Ventricular Diastolic Suction89
Angiotensin Tachyphylaxis and its Reversal89
T-type Ca2+ channels are abnormal in genetically determined cardiomyopathic hamster hearts.89
Electrical responses of smooth muscle cells during cholinergic vasodilation in the rabbit saphenous artery.89
Endogenous Nitric Oxide and Myocardial Adaptation to Ischemia89
Modification by Acetylcholine of the Response of Rat Mesenteric Arteries to Sympathetic Stimulation89
Contrasting effects of static and pulsatile pressure on carotid baroreceptor activity in dogs.89
Conscious rabbits become tolerant to multiple episodes of ischemic preconditioning.89
Blood-tissue exchange via transport and transformation by capillary endothelial cells.89
Influence of heart rate on left ventricular performance in conscious dogs.89
Endotoxin-Induced Myocardial Dysfunction89
An Angiocardiographic Method for Directly Determining Left Ventricular Stroke Volume in Man89
Versican Expression Is Associated With Chamber Specification, Septation, and Valvulogenesis in the Developing Mouse Heart89
Human Serum Dopamine-β-Hydroxylase: Relationship to Hypertension and Sympathetic Activity89
cGMP-Dependent Protein Kinase Regulation of the L-Type Ca 2+ Current in Rat Ventricular Myocytes89
Developmental aspects of the renal response to hypoxemia in the lamb fetus.89
Caveolae Localize Protein Kinase A Signaling to Arterial ATP-Sensitive Potassium Channels89
CHF1/Hey2 Plays a Pivotal Role in Left Ventricular Maturation Through Suppression of Ectopic Atrial Gene Expression89
Tonic influence of the sympathetic nervous system on myocardial reactive hyperemia and on coronary blood flow distribution in dogs.89
Cerebral Microvascular Responses to Hypercholesterolemia89
Cell Replication in the Arterial Wall89
Regional Uptake of Radioactive Oxygen, Carbon Monoxide and Carbon Dioxide in the Lungs of Patients with Mitral Stenosis89
Reduced Myocardial Nerve Growth Factor Expression in Human and Experimental Heart Failure89
Subunit-dependent modulation of recombinant L-type calcium channels. Molecular basis for dihydropyridine tissue selectivity.89
Renal Vascular Responses to Angiotensin and Norepinephrine in Normal Man: EFFECT OF SODIUM INTAKE89
Comparison of the Force-Velocity Relation and the Ventricular Function Curve as Measures of the Contractile State of the Intact Heart89
Stimulation by bradykinin of afferent vagal C-fibers with chemosensitive endings in the heart and aorta of the dog.89
Nicotinic Acid Adenine Dinucleotide Phosphate Mediates Ca 2+ Signals and Contraction in Arterial Smooth Muscle via a Two-Pool Mechanism89
Calpain-Mediated Impairment of Na + /K + –ATPase Activity During Early Reperfusion Contributes to Cell Death After Myocardial Isch89
Hyperinsulinemia Enhances Transcriptional Activity of Nuclear Factor-κB Induced by Angiotensin II, Hyperglycemia, and Advanced Glycosylation End Products in Vascular Smooth Muscle Cells89
Tissue-Specific Induction of Intestinal ABCA1 Expression With a Liver X Receptor Agonist Raises Plasma HDL Cholesterol Levels89
Aldosteronism and Peripheral Blood Mononuclear Cell Activation89
Platelet-Derived Growth Factor-BB–Induced Human Smooth Muscle Cell Proliferation Depends on Basic FGF Release and FGFR-1 Activation89
Overexpression of Inducible Nitric Oxide Synthase in Rostral Ventrolateral Medulla Causes Hypertension and Sympathoexcitation via an Increase in Oxidative Stress89
Transferable lipids in oxidized low-density lipoprotein stimulate plasminogen activator inhibitor-1 and inhibit tissue-type plasminogen activator release from endothelial cells.89
Fetal-Derived Trophoblast Use the Apoptotic Cytokine Tumor Necrosis Factor-α–Related Apoptosis-Inducing Ligand to Induce Smooth Muscle Cell Death89
Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand (TRAIL) Sequentially Upregulates Nitric Oxide and Prostanoid Production in Primary Human Endothelial Cells89
A Variant of p22 phox , Involved in Generation of Reactive Oxygen Species in the Vessel Wall, Is Associated With Progression of Co89
Intimal Smooth Muscle Cells of Porcine and Human Coronary Artery Express S100A4, a Marker of the Rhomboid Phenotype In Vitro89
Potentiation of the Actions of Bradykinin by Angiotensin I–Converting Enzyme Inhibitors89
Regulation of large coronary arteries.88
Calcium current is increased in isolated adult myocytes from hypertrophied rat myocardium.88
The Matricellular Protein CCN1 Is Essential for Cardiac Development88
Multiple types of Ca2+ currents in single canine Purkinje cells.88
Pulsatile Pressure and Flow Through Distensible Vessels88
Hemodynamic Effects of Quantitatively Varied Experimental Mitral Regurgitation88
Regulation of vascular angiotensin II receptors in the rat during altered sodium intake.88
The elasticity of canine and human coronary arteries with reference to postmortem changes.88
Influence of Pituitary, Thyroid, and Adrenal Hormones on Norepinephrine Turnover and Metabolismin the Rat Heart88
Mechanics of cerebral arterioles in hypertensive rats.88
Autocrine Regulation of Myocyte Cx43 Expression by VEGF88
Myoplasmic calcium, myosin phosphorylation, and regulation of the crossbridge cycle in swine arterial smooth muscle.88
Reconstruction of propagated electrical activity with a two-dimensional model of anisotropic heart muscle.88
Reduction of the Cardiac Response to Postganglionic Sympathetic Nerve Stimulation in Experimental Heart Failure88
Static Elastic Properties of the Left Coronary Circumflex Artery and the Common Carotid Artery in Dogs88
Myocardial Necrosis in Rats: Serum Enzymes, Adrenal Steroid and Histopathological Alterations88
Carotid sinus baroreceptor reflex control of respiration.88
Lung fluid exchange after uneven pulmonary artery obstruction in sheep.88
Load responsiveness of protein synthesis in adult mammalian myocardium: role of cardiac deformation linked to sodium influx.88
The effect of agents interfering with soft tissue calcification and cell proliferation on calcific fibrous-fatty plaques in rabbits.88
Removal of the endothelium potentiates canine large coronary artery constrictor responses to 5-hydroxytryptamine in vivo.88
Decreased pressor reactivity to angiotensin II in cirrhotic rats. Evidence for a post-receptor defect in angiotensin action.88
Electrical and mechanical restitution of the human heart at different rates of stimulation.88
Regulation of the postsynaptic alpha-adrenergic receptor in rat mesenteric artery. Effects of chemical sympathectomy and epinephrine treatment.88
Adenosine Inhibits Lipopolysaccharide-Induced Cardiac Expression of Tumor Necrosis Factor-α88
Cardiac Arrhythmias Following Condenser Discharges and Their Dependence Upon Strength of Current and Phases of Cardiac Cycle88
Release of vasodilator prostaglandin, PGI2, from isolated rat lung during vasoconstriction.88
Ventricular contracture and compliance changes with global ischemia and reperfusion, and their effect on coronary resistance in the rat.88
The Excitability Cycle of the Dog's Left Ventricle Determined by Anodal, Cathodal, and Bipolar Stimulation88
Estradiol Inhibits Leukocyte Adhesion and Transendothelial Migration in Rabbits In Vivo88
Nitric Oxide Regulates Transforming Growth Factor-β Signaling in Endothelial Cells88
Regeneration of myocardial phosphocreatine in pigs despite continued moderate ischemia.88
Expression of basic fibroblast growth factor and its receptor by smooth muscle cells and endothelium in injured rat arteries. An en face study.88
Angiotensin II stimulates two myelin basic protein/microtubule-associated protein 2 kinases in cultured vascular smooth muscle cells.88
Virtual cathode effects during stimulation of cardiac muscle. Two-dimensional in vivo experiments.88
Different functions of the platelet-derived growth factor-alpha and -beta receptors for the migration and proliferation of cultured baboon smooth muscle cells.88
Pulse wave reflection: can it explain the differences between systemic and pulmonary pressure and flow waves? A study in dogs.88
Upregulation of 5′-AMP–Activated Protein Kinase Is Responsible for the Increase in Myocardial Fatty Acid Oxidation Rates Following Birth in the Newborn Rabbit88
Reverse Mode of the Na + -Ca 2+ Exchange After Myocardial Stretch88
Mechanisms of Stretch-Induced Changes in [Ca 2+ ] i in Rat Atrial Myocytes88
Effects of high and low sodium intake on arterial pressure and forearm vasular resistance in borderline hypertension. A preliminary report.88
Minocycline Exerts Multiple Inhibitory Effects on Vascular Endothelial Growth Factor–Induced Smooth Muscle Cell Migration88
A Role for Ca 2+ /Calmodulin-Dependent Protein Kinase II in the Mitogen-Activated Protein Kinase Signaling Cascade of Cultured Rat Aortic Vascular Smooth Muscle Cell88
Downregulation of Connexin 45 Gene Products During Mouse Heart Development88
Paclitaxel Enhances Thrombin-Induced Endothelial Tissue Factor Expression via c-Jun Terminal NH 2 Kinase Activation88
Coordinated Control of Cell Ca 2+ Loading and Triggered Release From the Sarcoplasmic Reticulum Underlies the Rapid Inotropic Response to Increased L-Type Ca 88
Peroxisome Proliferator–Activated Receptor α Induces NADPH Oxidase Activity in Macrophages, Leading to the Generation of LDL with PPAR-α Activation Properties88
Inhibition of Lipopolysaccharide-Induced Inflammatory Responses by an Apolipoprotein AI Mimetic Peptide88
Action of Tropoelastin and Synthetic Elastin Sequences on Vascular Tone and on Free Ca 2+ Level in Human Vascular Endothelial Cells88
Enhanced Myocardial Contractility and Increased Ca 2+ Transport Function in Transgenic Hearts Expressing the Fast-Twitch Skeletal Muscle Sarcoplasmic Reticulum Ca 88
Inhibitory Effects of Novel AP-1 Decoy Oligodeoxynucleotides on Vascular Smooth Muscle Cell Proliferation In Vitro and Neointimal Formation In Vivo88
Platelets, Fatty Acids and Thrombosis87
Mitochondrial Oxidative Stress in Heart Failure87
Arterial Lesions in the Kenya Baboon87
Simvastatin Attenuates Oxidant-Induced Mitochondrial Dysfunction in Cardiac Myocytes87
Prostaglandin synthesis by bovine mesenteric arteries and veins.87
Observations on the Ventricular Dysrhythmia Associated with Atrial Fibrillation in the Dog Heart87
Influence of Reserpine and βTM 10 on Digitalis-Induced Ventricular Arrhythmia87
Transcriptional Profiling of the Heart Reveals Chamber-Specific Gene Expression Patterns87
Antagonistic effects of theophylline and adenosine on adrenergic neuroeffector transmission in the rabbit kidney.87
Peroxisome Proliferator-Activated Receptor α Reduces Cholesterol Esterification in Macrophages87
Characteristics of flow-mediated brachial artery vasodilation in human subjects.87
Distinct Renin Isoforms Generated by Tissue-Specific Transcription Initiation and Alternative Splicing87
Antihypertensive Effect of Clonidine87
Purification and Properties of Angiotensin-Converting Enzyme from Hog Lung87
Effects of Mineralocorticoids, Altered Sodium Intake, and Adrenalectomy on Urinary Kallikrein in Rats87
Cardioprotection of Preconditioning by Metabolic Inhibition in the Rat Ventricular Myocyte87
5-Lipoxygenase–Activating Protein87
Stimulation of pulmonary vagal afferent C-fibers by lung edema in dogs.87
COX-2–Derived Prostacyclin Modulates Vascular Remodeling87
Expression and Phosphorylation of the Na-Pump Regulatory Subunit Phospholemman in Heart Failure87
Akt Promotes Increased Cardiomyocyte Cycling and Expansion of the Cardiac Progenitor Cell Population87
Subendomyocardial exhaustion of blood flow reserve and increased fibrosis in conscious dogs with heart failure.87
Regulation of vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 in human vascular smooth muscle cells.87
Lysophosphatidylcholine Promotes P-Selectin Expression in Platelets and Endothelial Cells87
Control of Complete Heart Block by Use of an Artificial Pacemaker and a Myocardial Electrode87
Effects of intracoronary administration of bradykinin on the impulse activity of afferent sympathetic unmyelinated fibers with left ventricular endings in the cat.87
Characterization of Gap Junction Channels in Adult Rabbit Atrial and Ventricular Myocardium87
Inhibition of Cytochrome P450ω-Hydroxylase87
Vasorelaxation by Red Blood Cells and Impairment in Diabetes87
Increased Myogenic Tone and Diminished Responsiveness to ATP-Sensitive K + Channel Openers in Cerebral Arteries From Diabetic Rats87
Phosphatidylinositol 3-Kinase Functionally Compartmentalizes the Concurrent G s Signaling During β 2 -Adrenergic Stimulation87
Hypoxia and Hypoxia/Reoxygenation Activate Raf-1, Mitogen-Activated Protein Kinase Kinase, Mitogen-Activated Protein Kinases, and S6 Kinase in Cultured Rat Cardiac Myocytes87
Early Activation of the Multicomponent Signaling Complex Associated With Focal Adhesion Kinase Induced by Pressure Overload in the Rat Heart87
Intracellular Ca 2+ , Intercellular Electrical Coupling, and Mechanical Activity in Ischemic Rabbit Papillary Muscle87
Modulation of Ras/Raf/Extracellular Signal–Regulated Kinase Pathway by Reactive Oxygen Species Is Involved in Cyclic Strain–Induced Early Growth Response-1 Gene Expression in Endothelial Cells87
Physiological concentrations of nitric oxide do not elicit an acute negative inotropic effect in unstimulated cardiac muscle.87
MCIP1 Overexpression Suppresses Left Ventricular Remodeling and Sustains Cardiac Function After Myocardial Infarction87
Aorta of ApoE-Deficient Mice Responds to Atherogenic Stimuli by a Prelesional Increase and Subsequent Decrease in the Expression of Antioxidant Enzymes87
High and Low Molecular Weight Fibroblast Growth Factor-2 Increase Proliferation of Neonatal Rat Cardiac Myocytes but Have Differential Effects on Binucleation and Nuclear Morphology87
Phorbol ester and dioctanoylglycerol stimulate membrane association of protein kinase C and have a negative inotropic effect mediated by changes in cytosolic Ca2+ in adult rat cardiac myocytes.87
Cardiac Overexpression of Melusin Protects From Dilated Cardiomyopathy Due to Long-Standing Pressure Overload87
Atherosclerotic Conditions Promote the Packaging of Functional MicroRNA-92a-3p Into Endothelial Microvesicles87
General Theory of Heart-Vector Projection86
Nonadrenergic neural vasodilator mechanisms.86
CD40-CD40L and Platelet Function86
Interferon-γ Axis in Graft Arteriosclerosis86
Ras, Akt, and Mechanotransduction in the Cardiac Myocyte86
Uptake and Release of Cholesterol by Rabbit Atheromatous Lesions86
Vascular Smooth Muscle and the Anisotropy of Dog Carotid Artery86
Electrophysiological Study of Human Heart Muscle86
Inhibition of aldosterone biosynthesis by atriopeptins in rat adrenal cells.86
Role of Gap Junctions in Cardiac Conduction and Development86
Substructure of intercellular junctions in freeze-fractured alveolar-capillary membranes of mouse lung.86
Endothelin Peptide and Receptors in Human Atherosclerotic Coronary Artery and Aorta86
L-arginine evokes both endothelium-dependent and -independent relaxations in L-arginine-depleted aortas of the rat.86
Contribution of Kinins to Endotoxin Shock in Unanesthetized Rhesus Monkeys86
Axl, A Receptor Tyrosine Kinase, Mediates Flow-Induced Vascular Remodeling86
Analysis of cranial neural crest distribution in the developing heart using quail-chick chimeras.86
Blockade of beta 1-integrins in skin causes edema through lowering of interstitial fluid pressure.86
Effect of the thyroid state on the enzymatic characteristics of cardiac myosin. A difference in behavior of rat and rabbit cardiac myosin.86
Creatine Kinase Is the Main Target of Reactive Oxygen Species in Cardiac Myofibrils86
Adenovirus-Mediated Gene Transfer In Vivo to Cerebral Blood Vessels and Perivascular Tissue86
Tumor-promoting phorbol esters inhibit cardiac functions and induce redistribution of protein kinase C in perfused beating rat heart.86
Efflux of metabolized and nonmetabolized fatty acid from canine myocardium. Implications for quantifying myocardial metabolism tomographically.86
Restoration of Resting Sarcomere Length After Uniaxial Static Strain Is Regulated by Protein Kinase Cε and Focal Adhesion Kinase86
Effect of Respiration on Venous Return and Stroke Volume in Cardiac Tamponade86
Modulation of Ca 2+ Channels by Cyclic Nucleotide Cross Activation of Opposing Protein Kinases in Rabbit Portal Vein86
Nitric Oxide Synthase (NOS3)–Mediated Cholinergic Modulation of Ca 2+ Current in Adult Rabbit Atrioventricular Nodal Cells86
Interleukin 12 Induces T-Cell Recruitment Into the Atherosclerotic Plaque86
Endothelin-1 enhances calcium entry through T-type calcium channels in cultured neonatal rat ventricular myocytes.86
Spatial and Temporal Inhomogeneities During Ca 2+ Release From the Sarcoplasmic Reticulum in Pig Ventricular Myocytes86
De Novo Expression of Macrophage Migration Inhibitory Factor in Atherogenesis in Rabbits86
Cardiac Sympathetic Rejuvenation86
Factors Contributing to the Reversible Pulmonary Hypertension of Patients with Acute Respiratory Failure Studied by Serial Observations during Recovery86
Insulin-Like Growth Factor-I Regulates Proliferation and Osteoblastic Differentiation of Calcifying Vascular Cells via Extracellular Signal-Regulated Protein Kinase And Phosphatidylinositol 3-Kinase P86
Functional Deletion Mutation of the 5′-Flanking Region of Type A Human Natriuretic Peptide Receptor Gene and Its Association With Essential Hypertension and Left Ventricular Hypertrophy in the Japanes86
Extracellular DNA NET-Works With Dire Consequences for Health86
Ontogeny of Local Sarcoplasmic Reticulum Ca 2+ Signals in Cerebral Arteries86
Transcriptomic Profiling of the Developing Cardiac Conduction System at Single-Cell Resolution86
Bradykinin, Digital Blood Flow, and the Arteriovenous Anastomoses85
Characterization of acetylcholine-induced membrane hyperpolarization in endothelial cells.85
Neurogenic sympathetic vasoconstriction of the rabbit basilar artery.85
Sino-Atrial Reciprocation in the Isolated Rabbit Heart85
Adrenergic coronary vasoconstriction helps maintain uniform transmural blood flow distribution during exercise.85
Release of endothelium-derived relaxing factor from human umbilical vessels.85
Positive Inotropic Effects of Dibutyryl Cyclic Adenosine 3',5'-Monophosphate85
Chronic progressive pressure overload of the cat right ventricle.85
Effects of Acetylcholine on Single Fibers of the Atrioventricular Node85
Gene Expression of Natriuretic Peptide Receptors in Myocardial Cells85
Oxidized LDL Promotes Peroxide-Mediated Mitochondrial Dysfunction and Cell Death in Human Macrophages85
Changes in Central Venous Pressure after Moderate Hemorrhage and Transfusion in Man85
Background potassium current active during the plateau of the action potential in guinea pig ventricular myocytes.85
Mechanisms of pulmonary edema induced by tumor necrosis factor-alpha.85
Bradykinin Production Associated with Oxygenation of the Fetal Lamb85
Effects of spontaneous respiration on canine left ventricular function.85
Ventricular Arrhythmias Induced by Sympathomimetic Amines in Unanesthetized Dogs Following Coronary Artery Occlusion85
Variation in the Velocity, Deformation, and Adhesion Energy Density of Leukocytes Rolling Within Venules85
Comparison of Ion-Channel Subunit Expression in Canine Cardiac Purkinje Fibers and Ventricular Muscle85
Morphometric Basis of the Sheet-Flow Concept of the Pulmonary Alveolar Microcirculation in the Cat85
Dependency of Pial Arterial and Arteriolar Diameter on Perivascular Osmolarity in the Cat85
Hyperplastic growth response of vascular smooth muscle cells following induction of acute hypertension in rats by aortic coarctation.85
Relation Between Left Ventricular Diastolic Pressure and Myocardial Segment Length and Observations on the Contribution of Atrial Systole85
Focal Adhesion Kinase Is Required for Blood Vessel Morphogenesis85
Calcium current in single cells isolated from normal and hypertrophied rat heart. Effects of beta-adrenergic stimulation.85
Total and regional cerebral blood flow during hypotension, hypertension, and hypocapnia. Effect of sympathetic denervation in dogs.85
Ventricular trabeculations in the chick embryo heart and their contribution to ventricular and muscular septal development.85
Reduced myocardial reflow and increased coronary vascular resistance following prolonged myocardial ischemia in the dog.85
Redistribution of collateral blood flow from necrotic to surviving myocardium following coronary occlusion in the dog.85
Distribution of a Persistent Sodium Current Across the Ventricular Wall in Guinea Pigs85
Homocysteine Enhances Neutrophil-Endothelial Interactions in Both Cultured Human Cells and Rats In Vivo85
Developmental changes in membrane Ca2+ and K+ currents in fetal, neonatal, and adult rabbit ventricular myocytes.85
Active modulation of electrical coupling between cardiac cells of the dog. A mechanism for transient and steady state variations in conduction velocity.85
Effects of lysolipids and oxidatively modified low density lipoprotein on endothelium-dependent relaxation of rabbit aorta.85
Neuropeptide control of rat gastric mucosal blood flow. Increase by calcitonin gene-related peptide and vasoactive intestinal polypeptide, but not substance P and neurokinin A.85
Peroxisome Proliferator-Activated Receptor γ Ligands Inhibit Rho/Rho Kinase Pathway by Inducing Protein Tyrosine Phosphatase SHP-285
Mechanism of early contractile failure during hypoxia in intact ferret heart: evidence for modulation of maximal Ca2+-activated force by inorganic phosphate.85
Interaction of α9β1 Integrin With Thrombospondin-1 Promotes Angiogenesis85
Heart Failure in Rats Causes Changes in Skeletal Muscle Morphology and Gene Expression That Are Not Explained by Reduced Activity85
JE mRNA accumulates rapidly in aortic injury and in platelet-derived growth factor-stimulated vascular smooth muscle cells.85
Complex I Dysfunction and Tolerance to Nitroglycerin85
Role of Nitric Oxide in the Control of Renal Oxygen Consumption and the Regulation of Chemical Work in the Kidney85
Conditional Neuronal Nitric Oxide Synthase Overexpression Impairs Myocardial Contractility85
Getting to the Heart of Alzheimer Disease85
An Analysis of Arrhythmias Induced by Ouabain in Intact Dogs84
Ca 2+ Waves in Lung Capillary Endothelium84
Mechanisms mediating the coronary vascular response to behavioral stress in the dog.84
Characteristics of rat aortic baroreceptors with nonmedullated afferent nerve fibers.84
Cholesteryl Ester Synthesis in Normal and Atherosclerotic Aortas of Rabbits and Rhesus Monkeys84
Slow Conduction in Cardiac Tissue, II84
Modulation of Ca2+ release in cultured neonatal rat cardiac myocytes. Insight from subcellular release patterns revealed by confocal microscopy.84
The effect of hypoxia on the regional distribution of cardiac output in the dog.84
Rate of Tension Development in Cardiac Muscle Varies With Level of Activator Calcium84
Circulatory reflexes from carotid and extracarotid baroreceptor areas in man.84
Dynamic Modulation of Interendothelial Gap Junctional Communication by 11,12-Epoxyeicosatrienoic Acid84
α 7 -Nicotinic Acetylcholine Receptors on Cerebral Perivascular Sympathetic Nerves Mediate Choline-Induced Nitrergic Neurogenic Vasodilation84
Increase in cross-linking of type I and type III collagens associated with volume-overload hypertrophy.84
Myocardial High Energy Phosphate Stores in Cardiac Hypertrophy and Heart Failure84
Expression of Inducible Nitric Oxide Synthase Inhibits Platelet Adhesion and Restores Blood Flow in the Injured Artery84
Differential Expression of Voltage-Gated K + Channel Genes in Left Ventricular Remodeled Myocardium After Experimental Myocardial Infarction84
Simultaneous Measurements of Ca 2+ and Nitric Oxide in Bradykinin-Stimulated Vascular Endothelial Cells84
Effect of an Early Atrial Premature Beat on Activity of the Sinoatrial Node and Atrial Rhythm in the Rabbit84
Na + -Ca 2+ Exchange Activity Is Localized in the T-Tubules of Rat Ventricular Myocytes84
Mechanism of decreased right and left ventricular end-diastolic volumes during continuous positive-pressure ventilation in dogs.84
Immunologic identification of Na+,K(+)-ATPase isoforms in myocardium. Isoform change in deoxycorticosterone acetate-salt hypertension.84
Age-Related Changes in Vascular Endothelial Growth Factor Dependency and Angiopoietin-1-Induced Plasticity of Adult Blood Vessels84
Synchronous occurrence of spontaneous localized calcium release from the sarcoplasmic reticulum generates action potentials in rat cardiac ventricular myocytes at normal resting membrane potential.84
Pacing-induced Heterogeneities in Intracellular Ca 2+ Signaling, Cardiac Alternans, and Ventricular Arrhythmias in Intact Rat Heart84
Expression of cGMP-Dependent Protein Kinase I and Phosphorylation of Its Substrate, Vasodilator-Stimulated Phosphoprotein, in Human Endothelial Cells of Different Origin84
β-Adrenergic Stimulation of L-type Ca 2+ Channels in Cardiac Myocytes Requires the Distal Carboxyl Terminus of α 1C but Not Serine84
Protein Kinase D Selectively Targets Cardiac Troponin I and Regulates Myofilament Ca 2+ Sensitivity in Ventricular Myocytes84
Outside-In Signals Delivered by Matrix Metalloproteinase-1 Regulate Platelet Function84
Flow-Dependent Remodeling of Small Arteries in Mice Deficient for Tissue-Type Transglutaminase84
Effects of the Renin-Angiotensin System on the Current I to in Epicardial and Endocardial Ventricular Myocytes From the Canine Heart84
Elevated plasma norepinephrine concentrations in decompensated cirrhosis. Association with increased secretion rates, normal clearance rates, and suppressibility by central blood volume expansion.84
Compensatory Mechanisms Associated With the Hyperdynamic Function of Phospholamban-Deficient Mouse Hearts84
FcγRIIB Mediates C-Reactive Protein Inhibition of Endothelial NO Synthase84
Effects of Antisense c- myb Oligonucleotides on Vascular Smooth Muscle Cell Proliferation and Response to Vessel Wall Injury84
Mechanisms Underlying the Impairment of Ischemia-Induced Neovascularization in Matrix Metalloproteinase 2–Deficient Mice84
Hypertension-Linked Mutation in the Adducin α-Subunit Leads to Higher AP2-μ2 Phosphorylation and Impaired Na + ,K + -ATPase Traffi84
Forkhead Transcription Factor FOXO3a Is a Negative Regulator of Angiogenic Immediate Early Gene CYR61, Leading to Inhibition of Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia84
Cardiac transmembrane potentials and metabolism.84
Muscle Pumping in the Dependent Leg84
Thixotropy of Blood and Proneness to Thrombus Formation84
Elasticity of the Pulmonary Alveolar Sheet84
Spinal Sympathetic Cardiocardiac Reflexes84
Seven-Transmembrane Receptors and Ubiquitination83
Hemodynamic role of extracellular fluid in hypertension.83
Regulation of Vascular Inflammation and Remodeling by ETS Factors83
Movements of the Mitral Valve83
Effects of NO Modulation on Cardiac Arrhythmias in the Rat Isolated Heart83
Arterial fibrous proteins in cynomolgus monkeys after atherogenic and regression diets.83
Calcium, sodium, and the calcium paradox.83
Thermal Dilution Curves in the Intact Animal83
Effect of platelet factors on migration of cultured bovine aortic endothelial and smooth muscle cells.83
Activation of β-Adrenergic Receptor Kinase During Myocardial Ischemia83
Expansion of acute myocardial infarction: its relationship to infarct morphology in a canine model.83
Myocardial Infarction Following Coronary Ligation in Dogs83
Blood Rheology: Effect of Fibrinogen Deduced by Addition83
18-Hydroxy-Deoxycorticosterone in Human Hypertension83
Contractility in Isolated Mammalian Heart Muscle after Acid-Base Changes83
Patterns of Sympathetic Nerve Projections onto the Canine Heart83
Pulsatile Stretch in Coronary Arteries Elicits Release of Endothelium-Derived Hyperpolarizing Factor83
Laminar Shear Stress Upregulates Integrin Expression83
Soluble Adenylyl Cyclase Reveals the Significance of cAMP Compartmentation on Pulmonary Microvascular Endothelial Cell Barrier83
Superoxide Released to High Intra-arteriolar Pressure Reduces Nitric Oxide–Mediated Shear Stress– and Agonist-Induced Dilations83
Small coronary vessel pressure and diameter in an intact beating rabbit heart using fixed-position and free-motion techniques.83
Renin Release after Hemorrhage and after Suprarenal Aortic Constriction in Dogs without Sodium Delivery to the Macula Densa83
Fibulin-5 Is a Novel Binding Protein for Extracellular Superoxide Dismutase83
Increased In Vivo Expression and Production of Endothelin-1 by Porcine Cardiomyocytes Subjected to Ischemia83
Abnormal Cardiac Conduction and Morphogenesis in Connexin40 and Connexin43 Double-Deficient Mice83
On the mechanism underlying the action of D-600 on slow inward current and tension in mammalian myocardium.83
Effect of Ventricular Rate on the Cardiac Output in the Dog with Chronic Heart Block83
Decreased Flow-Dependent Dilation in Carotid Arteries of Tissue Kallikrein–Knockout Mice83
Anisotropic Activation Spread in Heart Cell Monolayers Assessed by High-Resolution Optical Mapping83
Chronic Extrinsic Cardiac Denervation by Regional Neural Ablation83
Lysophosphatidylcholine inhibits surface receptor-mediated intracellular signals in endothelial cells by a pathway involving protein kinase C activation.83
Evidence From a Novel Human Cell Clone That Adult Vascular Smooth Muscle Cells Can Convert Reversibly Between Noncontractile and Contractile Phenotypes83
Transfer of Wild-Type p53 Gene Effectively Inhibits Vascular Smooth Muscle Cell Proliferation In Vitro and In Vivo83
Endothelial-to-Mesenchymal Transition83
Canine Ventricular Myocytes Possess a Renin-Angiotensin System That Is Upregulated With Heart Failure83
Continuous Nitric Oxide Inhalation Reduces Pulmonary Arterial Structural Changes, Right Ventricular Hypertrophy, and Growth Retardation in the Hypoxic Newborn Rat83
12/13 Mediates α 1 -Adrenergic Receptor–Induced Cardiac Hypertrophy83
Mechanisms of Atrial Fibrillation Termination by Pure Sodium Channel Blockade in an Ionically-Realistic Mathematical Model83
Role of α 4 Integrin and VCAM-1 in CD18-Independent Neutrophil Migration Across Mouse Cardiac Endothelium83
A monoclonal antibody against rabbit tissue factor inhibits thrombus formation in stenotic injured rabbit carotid arteries.83
Rho/Rho-Kinase Pathway in Brain Stem Contributes to Blood Pressure Regulation via Sympathetic Nervous System83
The effects of alpha 2-adrenergic and serotonergic receptor antagonists on cyclic blood flow alterations in stenosed canine coronary arteries.83
Atrial Natriuretic Peptide Induces Mitogen-Activated Protein Kinase Phosphatase-1 in Human Endothelial Cells via Rac1 and NAD(P)H Oxidase/Nox2-Activation83
Positive Inotropic Effects by Uridine Triphosphate (UTP) and Uridine Diphosphate (UDP) via P2Y 2 and P2Y 6 Receptors on Cardiomyoc83
Concealed Conduction82
Mouse Mutants and Cardiac Development82
Pulse wave propagation.82
Mechanisms of Endothelial Cell Heterogeneity in Health and Disease82
Coronary Vasodilator Properties of Purine and Pyrimidine Derivatives82
Radioimmunoassay and Clearance of Circulating Dopamine-β-Hydroxylase82
Developmental Changes in Transient Outward Current in Mouse Ventricle82
The Augmentor Action of the Sympathetic Cardiac Nerves82
Direct Current Make and Break Thresholds for Pacemaker Electrodes on the Canine Ventricle82
Direct actions of cocaine on cardiac cellular electrical activity.82
Evidence for Specialized Fibers in the Canine Right Atrium82
Adenosine metabolism in canine myocardial reactive hyperemia.82
Correlation of force-length area with oxygen consumption in ferret papillary muscle.82
Coronary Hemodynamic Effects of Increasing Ventricular Rate in the Unanesthetized Dog82
Regulation of K+ channels in cardiac myocytes by free fatty acids.82
The canine heart as an electrocardiographic generator. Dependence on cardiac cell orientation.82
Influence of Atrial Systole on Effective Ventricular Stroke Volume82
Stimulation of angiogenesis by adenosine on the chick chorioallantoic membrane.82
Correlation of Visco-elastic Properties of Large Arteries with Microscopic Structure82
Transgenic Remodeling of the Contractile Apparatus in the Mammalian Heart82
Distribution of myocardial blood flow in the exercising dog with restricted coronary artery inflow.82
Inhibition of Nitric Oxide Synthesis Causes Myocardial Ischemia in Endotoxemic Rats82
Early and Late Effects of Coronary Artery Occlusion on Canine Purkinje Fibers82
Effect of Ischemia and Reoxygenation on Glycolytic Reactions and Adenosinetriphosphate in Heart Muscle82
Compartmentation of cAMP in adult canine ventricular myocytes. Relation to single-cell free Ca2+ transients.82
Thyroid Hormone Activation in Human Vascular Smooth Muscle Cells82
Alterations in Rat Interlobar Artery Membrane Potential and K + Channels in Genetic and Nongenetic Hypertension82
Nuclear RNA Foci in the Heart in Myotonic Dystrophy82
Effects of increasing intercellular resistance on transverse and longitudinal propagation in sheep epicardial muscle.82
Modulation of coronary autoregulatory responses by nitric oxide. Evidence for flow-dependent resistance adjustments in conscious dogs.82
Role of Mitogen-Activated Protein Kinases in Ischemia and Reperfusion Injury82
Time course of denervation of efferent sympathetic and vagal nerves after occlusion of the coronary artery in the canine heart.82
Responses of Cardiac Protein Kinase C Isoforms to Distinct Pathological Stimuli Are Differentially Regulated82
Do Glucose and Lipids Exert Independent Effects on Atherosclerotic Lesion Initiation or Progression to Advanced Plaques?82
Cyclic Variation of Intracellular Calcium82
Deletion of Microsomal Prostaglandin E Synthase-1 Increases Sensitivity to Salt Loading and Angiotensin II Infusion82
Steady-state mRNA levels of the sarcolemmal Na(+)-Ca2+ exchanger peak near birth in developing rabbit and rat hearts.82
Electron Microscopic Alterations at the Alveolar Level in Pulmonary Edema82
Altered cardiac responsiveness and regulation in the normal cardiac output type of borderlind hlpertension.82
Nitric oxide influences neuronal activity in the nucleus tractus solitarius of rat brainstem slices.82
Selective contribution of two types of carotid sinus baroreceptors to the control of blood pressure.82
Effects of Carotid Sinus Nerve Stimulation on Blood-Flow Distribution in Conscious Dogs at Rest and during Exercise82
Induction of Glutathione Synthesis in Macrophages by Oxidized Low-Density Lipoproteins Is Mediated by Consensus Antioxidant Response Elements82
The prostaglandin system. A role in canine baroreceptor control of renin release.82
Dissimilar effects of prostacyclin, prostaglandin E1, and prostaglandin E2 on myocardial infarct size after coronary occlusion in conscious dogs.82
Transcriptional Profile of Mechanically Induced Genes in Human Vascular Smooth Muscle Cells82
Decreased Obesity and Atherosclerosis in Human Paraoxonase 3 Transgenic Mice82
Ca 2+ ‘Sparks’ and Waves in Intact Ventricular Muscle Resolved by Confocal Imaging82
Platelet-Derived Growth Factor Ligand and Receptor Expression in Response to Altered Blood Flow In Vivo82
Endothelial Nitric Oxide Synthase Regulates Microlymphatic Flow via Collecting Lymphatics82
Factors modifying the early nondiuretic vascular effects of furosemide in man. The possible role of renal prostaglandins.82
Dual Mechanisms Regulating AMPK Kinase Action in the Ischemic Heart82
Differential effects of central angiotensin II and substance P on sympathetic nerve activity in conscious rats. Implications for cardiovascular adaptation to behavioral responses.82
Activation of the Endothelial Store-Operated I SOC Ca 2+ Channel Requires Interaction of Protein 4.1 With TRPC482
Small Heat-Shock Protein Hsp20 Attenuates β-Agonist–Mediated Cardiac Remodeling Through Apoptosis Signal–Regulating Kinase 182
Antioxidant Improves Smooth Muscle Sarco/Endoplasmic Reticulum Ca 2+ -ATPase Function and Lowers Tyrosine Nitration in Hypercholesterolemia and Improves Nitric Oxide82
Involvement of Src Family Protein Tyrosine Kinases in Ca 2+ Sensitization of Coronary Artery Contraction Mediated by a Sphingosylphosphorylcholine-Rho-Kinase Pathway82
Activation of D 3 Dopamine Receptor Decreases Angiotensin II Type 1 Receptor Expression in Rat Renal Proximal Tubule Cells82
Induction of Nitric Oxide Synthase Activity by Cytokines in Ventricular Myocytes Is Necessary but Not Sufficient to Decrease Contractile Responsiveness to β-Adrenergic Agonists82
Whole Exome Sequencing Reveals the Major Genetic Contributors to Nonsyndromic Tetralogy of Fallot82
Is there a brain renin-angiotensin system?81
Dynamics of Ventricular Ejection81
Do vasomotor nerves significantly regulate cerebral blood flow?81
Renal chemoreceptors in the rat.81
Evidence for Hemodynamic Autoregulation of Renin Release81
An examination of the measurement of flow heterogeneity in striated muscle.81
Sensitization of isolated canine coronary arteries to calcium ions after exposure to cholesterol.81
Vasomotor control of capillary transit time heterogeneity in the canine coronary circulation.81
Ventricular Function81
An atrial peptide is a potent renal vasodilator substance.81
Whole body vascular reactivity during the development of deoxycorticosterone acetate hypertension in the pig.81
Dance Band on the Titanic81
The Effect of Complete Ischemia on the Intracellular Electrical Activity of the Whole Mammalian Heart81
Integrin-Mediated Collagen Matrix Reorganization by Cultured Human Vascular Smooth Muscle Cells81
The influence of resting tension on immunoreactive atrial natriuretic peptide secretion by rat atria superfused in vitro.81
Effects of Estrogen and Progestogen Treatment on the Response of the Aorta of Male Rats to Hypertension: MORPHOLOGICAL AND CHEMICAL STUDIES81
Localization of Renin in Juxtaglomerular Cells of Rabbit and Dog Through the Use of the Fluorescent-Antibody Technique81
Effects of exercise on aortic input impedance and pressure wave forms in normal humans.81
Enhanced renal prostaglandin production in the dog. II. Effects on intrarenal hemodynamics.81
Sarcoplasmic Reticulum Ca 2+ /Calmodulin-Dependent Protein Kinase Is Altered in Heart Failure81
Systolic mechanical properties of the left ventricle. Effects of volume and contractile state.81
Ventricular arrhythmias in the subacute myocardial infarction period. High-resolution activation and refractory patterns of reentrant rhythms.81
Heterogeneity of ATP receptors in aortic endothelial cells. Involvement of P2y and P2u receptors in inositol phosphate response.81
Synthesis of lipoxygenase and epoxygenase products of arachidonic acid by normal and stenosed canine coronary arteries.81
Autonomic Control of Vasomotion in the Porcine Coronary Circulation During Treadmill Exercise81
Acute pulmonary hypertension and lung thromboxane release after endotoxin infusion in normal and leukopenic sheep.81
Distinct Pathways Regulate Expression of Cardiac Electrical and Mechanical Junction Proteins in Response to Stretch81
Cholesterol potentiates the coronary artery response to norepinephrine in anesthetized and conscious dogs.81
Modulation of Cystathionine β-Synthase Level Regulates Total Serum Homocysteine in Mice81
The relationship between ultrasonic pulsatility index and proximal arterial stenosis in a canine model.81
Regional changes in hemodynamics and cardiac myocyte size in rats with aortocaval fistulas. 1. Developing and established hypertrophy.81
Pulmonary Microvascular Permeability81
Selective Stimulation of Renal Nerves in the Anesthetized Dog81
Enhanced S -Nitroso-Albumin Formation From Inhaled NO During Ischemia/Reperfusion81
Chronic Inhalation of Nitric Oxide Inhibits Neointimal Formation After Balloon-Induced Arterial Injury81
Effects on the Canine P Wave of Discrete Lesions in the Specialized Atrial Tracts81
Biphasic Actions of Prostaglandin E 2 on the Renal Afferent Arteriole81
Sox4-Deficiency Syndrome in Mice Is an Animal Model for Common Trunk81
Molecular and Physiological Effects of α-Tropomyosin Ablation in the Mouse81
Augmented tissue oxygen supply during striated muscle contraction in the hamster. Relative contributions of capillary recruitment, functional dilation, and reduced tissue PO2.81
Rho-ROCK-LIMK-Cofilin Pathway Regulates Shear Stress Activation of Sterol Regulatory Element Binding Proteins81
Enhanced Ca 2+ Current and Decreased Ca 2+ Efflux Restore Sarcoplasmic Reticulum Ca 2+ Content 81
Attachment of Meandering Reentrant Wave Fronts to Anatomic Obstacles in the Atrium81
Use of aromatic hydroxylation of phenylalanine to measure production of hydroxyl radicals after myocardial ischemia in vivo. Direct evidence for a pathogenetic role of the hydroxyl radical in myocardi81
Heterodimerization of β 1 - and β 2 -Adrenergic Receptor Subtypes Optimizes β-Adrenergic Modulation of Cardiac Contractility81
Reduced Cardiac L-Type Ca 2+ Current in Ca v β 2 −/− Embryos Impairs Car81
A Dual Inhibitor of Platelet-Derived Growth Factor β-Receptor and Src Kinase Activity Potently Interferes With Motogenic and Mitogenic Responses to PDGF in Vascular Smooth Muscle Cells81
SARS-CoV-2 Initiates Programmed Cell Death in Platelets81
Vascular Tissue Engineering80
Interactions between behavior and the cardiovascular system.80
Architecture of Small Arteries during Vasoconstriction80
Mechanisms of automaticity in subsidiary pacemakers from cat right atrium.80
Noninvasive Imaging of Myocardial Viability80
Progressive Increases in Complexity of T-Wave Oscillations Herald Ischemia-Induced Ventricular Fibrillation80
Electrophysiological effects of acute ventricular dilatation in the isolated rabbit heart.80
Ventricular action potentials, ventricular extracellular potentials, and the ECG of guinea pig.80
Left Ventricular Performance During By-Pass or Distension of the Right Ventricle80
Tissue factor is expressed on monocytes during simulated extracorporeal circulation.80
Contracture in isolated adult rat heart cells. Role of Ca2+, ATP, and compartmentation.80
Mechanisms by which angiotensin II affects the heart rate of the conscious sheep.80
Strong Binding of Myosin Modulates Length-Dependent Ca 2+ Activation of Rat Ventricular Myocytes80
Flow-Dependent Regulation of Endothelial Toll-Like Receptor 2 Expression Through Inhibition of SP1 Activity80
Patterns of endothelial microfilament distribution in the rabbit aorta in situ.80
Spatiotemporal Development and Distribution of Intercellular Junctions in Adult Rat Cardiomyocytes in Culture80
Role of Histamine in Hypoxic Pulmonary Hypertension in the Rat80
Epicardial phenol interrupts refractory period responses to sympathetic but not vagal stimulation in canine left ventricular epicardium and endocardium.80
Degenerative Changes in the Cardiovascular System of the Spawning Pacific Salmon ( Oncorhynchus tshawytscha )80
Human Vascular Smooth Muscle Cells but Not Endothelial Cells Express Prostaglandin E Synthase80
Relation Between Mural Force and Pressure in the Left Ventricle of the Dog80
Potential fields on the ventricular surface of the exposed dog heart during normal excitation.80
Lipopolysaccharide Depresses Cardiac Contractility and β-Adrenergic Contractile Response by Decreasing Myofilament Response to Ca 2+ in Cardiac Myocytes80
Mechanical interactions between four heart chambers with and without the pericardium in canine hearts.80
Cytoprotection by Jun Kinase During Nitric Oxide–Induced Cardiac Myocyte Apoptosis80
Transcriptional Regulation of Inducible Nitric Oxide Synthase in Cultured Neonatal Rat Cardiac Myocytes80
NADH Oxidase Activity of Rat Cardiac Sarcoplasmic Reticulum Regulates Calcium-Induced Calcium Release80
Effect of acidosis on contraction of microvascular smooth muscle by alpha 1- and alpha 2-adrenoceptors. Implications for neural and metabolic regulation.80
Excitation–Contraction Coupling in Na + –Ca 2+ Exchanger Knockout Mice80
Unitary Cl Channels Activated by Cytoplasmic Ca 2+ in Canine Ventricular Myocytes80
Measurement of Na(+)-K+ pump current in isolated rabbit ventricular myocytes using the whole-cell voltage-clamp technique. Inhibition of the pump by oxidant stress.80
Mechanisms of supersensitivity to sympathomimetic amines in the chronically denervated heart of the conscious dog.80
Cyclin A/cdk2 Activation Is Involved in Hypoxia-Induced Apoptosis in Cardiomyocytes80
Characterization of [3H](+/-)carazolol binding to beta-adrenergic receptors. Application to study of beta-adrenergic receptor subtypes in canine ventricular myocardium and lung.80
Adenoviral Gene Transfer of FGF-5 to Hibernating Myocardium Improves Function and Stimulates Myocytes to Hypertrophy and Reenter the Cell Cycle80
Targeted Disruption of hesr2 Results in Atrioventricular Valve Anomalies That Lead to Heart Dysfunction80
Host Gene Regulation During Coxsackievirus B3 Infection in Mice80
Targeted Ablation of the Murine α-Tropomyosin Gene80
Inotropic responses to isoproterenol and phosphodiesterase inhibitors in intact guinea pig hearts: comparison of cyclic AMP levels and phosphorylation of sarcoplasmic reticulum and myofibrillar protei80
Kv1.5 Is an Important Component of Repolarizing K + Current in Canine Atrial Myocytes80
Functional Effects of Protein Kinase C Activation on the Human Cardiac Na sup + Channel80
Embryonic Heart Failure in NFATc1 −/− Mice80
A Mechanism of Transition From Ventricular Fibrillation to Tachycardia80
Angiotensin II Enhances Interleukin-18 Mediated Inflammatory Gene Expression in Vascular Smooth Muscle Cells80
PPARγ Agonists Ameliorate Endothelial Cell Activation via Inhibition of Diacylglycerol–Protein Kinase C Signaling Pathway80
Fcγ Receptor Deficiency Confers Protection Against Atherosclerosis in Apolipoprotein E Knockout Mice80
Hypercholesterolemia Suppresses Inwardly Rectifying K + Channels in Aortic Endothelium In Vitro and In Vivo80
Selective Matrix Metalloproteinase Inhibition With Developing Heart Failure80
Torsional deformation of the left ventricular midwall in human hearts with intramyocardial markers: regional heterogeneity and sensitivity to the inotropic effects of abrupt rate changes.80
Sarco/Endoplasmic Reticulum Ca 2+ -ATPase Gene Transfer Reduces Vascular Smooth Muscle Cell Proliferation and Neointima Formation in the Rat80
Inducible cAMP Early Repressor (ICER) Is a Negative-Feedback Regulator of Cardiac Hypertrophy and an Important Mediator of Cardiac Myocyte Apoptosis in Response to β-Adrenergic Receptor Stimulation80
Specific Mutations in ABCA1 Have Discrete Effects on ABCA1 Function and Lipid Phenotypes Both In Vivo and In Vitro80
Angiotensin II–Induced Transactivation of Epidermal Growth Factor Receptor Regulates Fibronectin and Transforming Growth Factor-β Synthesis via Transcriptional and Posttranscriptional Mechanisms80
Association of the APOLIPOPROTEIN A1/C3/A4/A5 Gene Cluster With Triglyceride Levels and LDL Particle Size in Familial Combined Hyperlipidemia80