Circulation Research

Papers
(The TQCC of Circulation Research is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-03-01 to 2024-03-01.)
ArticleCitations
Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System1365
Association of Inpatient Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers With Mortality Among Patients With Hypertension Hospitalized With COVID-19740
Obesity Phenotypes, Diabetes, and Cardiovascular Diseases676
Epidemiology of Atrial Fibrillation in the 21st Century587
COVID-19 and the Heart517
The Emerging Threat of (Micro)Thrombosis in COVID-19 and Its Therapeutic Implications425
Cardiac Energy Metabolism in Heart Failure418
Metabolic Inflammation and Insulin Resistance in Obesity415
Gut Microbiota and Cardiovascular Disease405
Interleukin-1 and the Inflammasome as Therapeutic Targets in Cardiovascular Disease384
Loss of Cardiac Ferritin H Facilitates Cardiomyopathy via Slc7a11-Mediated Ferroptosis359
Platelets Can Associate With SARS-CoV-2 RNA and Are Hyperactivated in COVID-19359
Epidemiology of Heart Failure351
Cardiomyocyte Maturation337
SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE 2282
Mitochondrial Determinants of Doxorubicin-Induced Cardiomyopathy272
Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics269
Basic Mechanisms of Diabetic Heart Disease264
Gut Microbiota–Derived Short-Chain Fatty Acids Promote Poststroke Recovery in Aged Mice252
Basic and Therapeutic Aspects of Angiogenesis Updated238
Obesity, Hypertension, and Cardiac Dysfunction238
Obesity, Adipose Tissue and Vascular Dysfunction236
Interleukin-6 Signaling and Anti-Interleukin-6 Therapeutics in Cardiovascular Disease224
COVID-19 and Cardiovascular Disease218
Molecular Basis of Atrial Fibrillation Pathophysiology and Therapy215
Arterial Stiffness and Cardiovascular Risk in Hypertension201
Meta-Analysis of Leukocyte Diversity in Atherosclerotic Mouse Aortas199
Social Determinants of Cardiovascular Disease198
Epidemiology of Peripheral Artery Disease and Polyvascular Disease191
Neutrophil Extracellular Traps Participate in Cardiovascular Diseases189
Sex as a Biological Variable in Atherosclerosis186
Targeting Mitochondria-Inflammation Circuit by β-Hydroxybutyrate Mitigates HFpEF182
Oxidative Stress and Hypertension181
Post-Stroke Cognitive Impairment and Dementia179
Myofibroblasts and Fibrosis173
In Situ Expansion, Differentiation, and Electromechanical Coupling of Human Cardiac Muscle in a 3D Bioprinted, Chambered Organoid169
Adiponectin, Leptin and Cardiovascular Disorders154
Atrial Myocyte NLRP3/CaMKII Nexus Forms a Substrate for Postoperative Atrial Fibrillation143
GSDMD-Mediated Cardiomyocyte Pyroptosis Promotes Myocardial I/R Injury140
The Impact of Sex and Gender on Stroke139
From Systemic Inflammation to Myocardial Fibrosis128
SARS-CoV-2 Initiates Programmed Cell Death in Platelets125
Clonal Hematopoiesis–Driver DNMT3A Mutations Alter Immune Cells in Heart Failure124
Regulatory T Cells License Macrophage Pro-Resolving Functions During Atherosclerosis Regression123
Celastrol Attenuates Angiotensin II–Induced Cardiac Remodeling by Targeting STAT3120
SIRT6 Protects Smooth Muscle Cells From Senescence and Reduces Atherosclerosis119
Arterial Stiffness Preceding Diabetes116
Intestinal Flora Modulates Blood Pressure by Regulating the Synthesis of Intestinal-Derived Corticosterone in High Salt-Induced Hypertension115
Intracellular and Intercellular Aspects of Macrophage Immunometabolism in Atherosclerosis111
Dynamics of Cardiac Neutrophil Diversity in Murine Myocardial Infarction109
Pathophysiology of Hypertension106
Genetics of Atrial Fibrillation in 2020103
Hypertension in Low- and Middle-Income Countries102
Pregnancy and Reproductive Risk Factors for Cardiovascular Disease in Women102
BMAL1-Downregulation Aggravates Porphyromonas Gingivalis -Induced Atherosclerosis by Encouraging Oxidative Stress101
The Tumor-Suppressive Human Circular RNA CircITCH Sponges miR-330-5p to Ameliorate Doxorubicin-Induced Cardiotoxicity Through Upregulating SIRT6, Survivin, and SERCA2a101
Role of the GLUT1 Glucose Transporter in Postnatal CNS Angiogenesis and Blood-Brain Barrier Integrity101
Noninvasive In Vivo Assessment of Cardiac Metabolism in the Healthy and Diabetic Human Heart Using Hyperpolarized 13 C MRI101
Reactive Oxygen-Forming Nox5 Links Vascular Smooth Muscle Cell Phenotypic Switching and Extracellular Vesicle-Mediated Vascular Calcification100
Cerebral Hemorrhage: Pathophysiology, Treatment, and Future Directions99
S100A9 Links Inflammation and Repair in Myocardial Infarction96
Polygenic Scores to Assess Atherosclerotic Cardiovascular Disease Risk93
Hematopoiesis and Cardiovascular Disease92
NAD + Repletion Reverses Heart Failure With Preserved Ejection Fraction91
Atherogenic Lipoprotein(a) Increases Vascular Glycolysis, Thereby Facilitating Inflammation and Leukocyte Extravasation91
Immune Cells and Immunotherapy for Cardiac Injury and Repair90
Inflammation, Infection and Venous Thromboembolism89
Single-Cell Analysis of Blood-Brain Barrier Response to Pericyte Loss87
Hypertension87
Platelet and Vascular Biomarkers Associate With Thrombosis and Death in Coronavirus Disease86
BET Epigenetic Reader Proteins in Cardiovascular Transcriptional Programs86
Cardiac Resident Macrophages Prevent Fibrosis and Stimulate Angiogenesis84
The Gut Microbiome in Hypertension82
Lymphatic Malformations: Genetics, Mechanisms and Therapeutic Strategies82
Klotho Deficiency Causes Heart Aging via Impairing the Nrf2-GR Pathway82
Metabolomics and Proteomics in Type 2 Diabetes81
AP-1 Contributes to Chromatin Accessibility to Promote Sarcomere Disassembly and Cardiomyocyte Protrusion During Zebrafish Heart Regeneration81
Genetic Basis and Therapies for Vascular Anomalies81
Cerebral Cavernous Malformation: From Mechanism to Therapy80
Gene Therapy for the Heart Lessons Learned and Future Perspectives80
Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension80
miR-128-3p Is a Novel Regulator of Vascular Smooth Muscle Cell Phenotypic Switch and Vascular Diseases80
New Directions in Therapeutic Angiogenesis and Arteriogenesis in Peripheral Arterial Disease78
A Critical Role for Estrogen-Related Receptor Signaling in Cardiac Maturation78
Molecular Genetic Basis of Hypertrophic Cardiomyopathy77
tPA Mobilizes Immune Cells That Exacerbate Hemorrhagic Transformation in Stroke77
Single Cell RNA Sequencing in Atherosclerosis Research77
Noncoding RNAs in Vascular Diseases76
Animal Models of Atrial Fibrillation76
Endothelium-Targeted Deletion of microRNA-15a/16-1 Promotes Poststroke Angiogenesis and Improves Long-Term Neurological Recovery75
Hyperglycemia Acutely Increases Cytosolic Reactive Oxygen Species via O -linked GlcNAcylation and CaMKII Activation in Mouse Ventricular Myocytes74
Transient Intermittent Hyperglycemia Accelerates Atherosclerosis by Promoting Myelopoiesis73
Mir-30d Regulates Cardiac Remodeling by Intracellular and Paracrine Signaling72
Advances in Revascularization for Peripheral Artery Disease: Revascularization in PAD70
Immune Pathways in Etiology, Acute Phase, and Chronic Sequelae of Ischemic Stroke70
Catecholamines Induce Trained Immunity in Monocytes In Vitro and In Vivo70
The Calcineurin-TFEB-p62 Pathway Mediates the Activation of Cardiac Macroautophagy by Proteasomal Malfunction69
Endothelial S1P 1 Signaling Counteracts Infarct Expansion in Ischemic Stroke67
Response by Zhang et al to Letter Regarding Article, “Association of Inpatient Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers With Mortality Among Patients With H66
Somatic Gain of KRAS Function in the Endothelium Is Sufficient to Cause Vascular Malformations That Require MEK but Not PI3K Signaling66
Modifiable Cardiovascular Risk, Hematopoiesis, and Innate Immunity64
Innervation and Neuronal Control of the Mammalian Sinoatrial Node a Comprehensive Atlas63
Downregulation of LAPTM4B Contributes to the Impairment of the Autophagic Flux via Unopposed Activation of mTORC1 Signaling During Myocardial Ischemia/Reperfusion Injury61
Racial and Ethnic Disparities in Peripheral Artery Disease60
Iron-Deficiency and Estrogen Are Associated With Ischemic Stroke by Up-Regulating Transferrin to Induce Hypercoagulability60
Coupling of Integrin α5 to Annexin A2 by Flow Drives Endothelial Activation59
Pathophysiology and Therapeutic Approaches to Acute Decompensated Heart Failure59
Sex Differences in Peripheral Artery Disease59
Single-Cell Epigenomics and Functional Fine-Mapping of Atherosclerosis GWAS Loci59
Lgr4 Governs a Pro-Inflammatory Program in Macrophages to Antagonize Post-Infarction Cardiac Repair59
AAV Gene Therapy Prevents and Reverses Heart Failure in a Murine Knockout Model of Barth Syndrome58
N-Cadherin Overexpression Mobilizes the Protective Effects of Mesenchymal Stromal Cells Against Ischemic Heart Injury Through a β-Catenin–Dependent Manner58
Genetic Regulation of Atherosclerosis-Relevant Phenotypes in Human Vascular Smooth Muscle Cells58
Inflammasomes and Proteostasis Novel Molecular Mechanisms Associated With Atrial Fibrillation58
Hypoalbuminemia, Coagulopathy, and Vascular Disease in COVID-1958
JAM-A Acts via C/EBP-α to Promote Claudin-5 Expression and Enhance Endothelial Barrier Function58
Multiscale Analysis of Extracellular Matrix Remodeling in the Failing Heart57
T-Cell–Derived miRNA-214 Mediates Perivascular Fibrosis in Hypertension57
Deficient Chaperone-Mediated Autophagy Promotes Inflammation and Atherosclerosis57
Advances in Acute Ischemic Stroke Therapy56
Histone Deacetylase 9 Activates IKK to Regulate Atherosclerotic Plaque Vulnerability56
Genetics Insights in the Relationship Between Type 2 Diabetes and Coronary Heart Disease56
KLF5 Is Induced by FOXO1 and Causes Oxidative Stress and Diabetic Cardiomyopathy55
Hypertension, a Moving Target in COVID-1955
Deletion of BACH1 Attenuates Atherosclerosis by Reducing Endothelial Inflammation55
Extreme Acetylation of the Cardiac Mitochondrial Proteome Does Not Promote Heart Failure54
Hypertension and Prohypertensive Antineoplastic Therapies in Cancer Patients53
RYR2 Channel Inhibition Is the Principal Mechanism of Flecainide Action in CPVT53
Population-Based Screening for Atrial Fibrillation53
A Computational Pipeline to Predict Cardiotoxicity52
CD84 Links T Cell and Platelet Activity in Cerebral Thrombo-Inflammation in Acute Stroke52
Contemporary Medical Management of Peripheral Artery Disease52
Gut Microbially Produced Indole-3-Propionic Acid Inhibits Atherosclerosis by Promoting Reverse Cholesterol Transport and Its Deficiency Is Causally Related to Atherosclerotic Cardiovascular Disease52
Epigenetic Age Acceleration Reflects Long-Term Cardiovascular Health51
Leveraging Machine Learning and Artificial Intelligence to Improve Peripheral Artery Disease Detection, Treatment, and Outcomes51
Emerging Technologies for Identifying Atrial Fibrillation50
Guideline-Driven Management of Hypertension50
Pathophysiology and Therapeutic Approaches to Cardiac Amyloidosis50
Glutamyl-Prolyl-tRNA Synthetase Regulates Proline-Rich Pro-Fibrotic Protein Synthesis During Cardiac Fibrosis50
The Complex and Diverse Genetic Architecture of Dilated Cardiomyopathy48
Vaccination Strategies and Immune Modulation of Atherosclerosis48
CARMN Loss Regulates Smooth Muscle Cells and Accelerates Atherosclerosis in Mice47
Endothelial Cell Receptors in Tissue Lipid Uptake and Metabolism47
Nonalcoholic Fatty Liver Disease: An Emerging Driver of Cardiac Arrhythmia47
Sex Differences in Myocardial and Vascular Aging47
LDL-Cholesterol Reduction by ANGPTL3 Inhibition in Mice Is Dependent on Endothelial Lipase46
Inflammation Resolution: Implications for Atherosclerosis46
Mechanisms of Cardiovascular Toxicities Associated With Immunotherapies46
Emerging Technologies for Pulmonary Vein Isolation46
Alternative Mitophagy Protects the Heart Against Obesity-Associated Cardiomyopathy46
Platelet and Megakaryocyte Roles in Innate and Adaptive Immunity45
The Molecular Basis of Predicting Atherosclerotic Cardiovascular Disease Risk45
Piezo1 Is a Mechanosensor Channel in Central Nervous System Capillaries45
MCU Overexpression Rescues Inotropy and Reverses Heart Failure by Reducing SR Ca 2+ Leak45
The Super-Relaxed State and Length Dependent Activation in Porcine Myocardium45
Gut Microbiome and Neuroinflammation in Hypertension44
Unveiling Complexity and Multipotentiality of Early Heart Fields44
Epigenetic and Transcriptional Networks Underlying Atrial Fibrillation44
Interaction of the Joining Region in Junctophilin-2 With the L-Type Ca 2+ Channel Is Pivotal for Cardiac Dyad Assembly and Intracellular Ca 2+44
CD31 as a Therapeutic Target in Atherosclerosis44
Machine Learning in Arrhythmia and Electrophysiology44
CircOGDH Is a Penumbra Biomarker and Therapeutic Target in Acute Ischemic Stroke44
Restructuring the Gut Microbiota by Intermittent Fasting Lowers Blood Pressure44
Self-Maintenance of Cardiac Resident Reparative Macrophages Attenuates Doxorubicin-Induced Cardiomyopathy Through the SR-A1-c-Myc Axis44
Metabolic and Molecular Imaging of the Diabetic Cardiomyopathy43
Disrupted Resolution Mechanisms Favor Altered Phagocyte Responses in COVID-1943
Leukocyte Heterogeneity in Adipose Tissue, Including in Obesity43
Heart Failure With Preserved Ejection Fraction: Heterogeneous Syndrome, Diverse Preclinical Models43
Reactivation of the Epicardium at the Origin of Myocardial Fibro-Fatty Infiltration During the Atrial Cardiomyopathy43
Histone Lactylation Boosts Reparative Gene Activation Post–Myocardial Infarction43
Brain Damage With Heart Failure43
SARS-CoV-2 Infection Induces Ferroptosis of Sinoatrial Node Pacemaker Cells43
EHD1 Modulates Cx43 Gap Junction Remodeling Associated With Cardiac Diseases42
LDL Receptor Regulates the Reverse Transport of Macrophage-Derived Unesterified Cholesterol via Concerted Action of the HDL-LDL Axis42
Erythrocyte Metabolic Reprogramming by Sphingosine 1-Phosphate in Chronic Kidney Disease and Therapies42
PPARγ-p53-Mediated Vasculoregenerative Program to Reverse Pulmonary Hypertension41
The Cancer Therapy-Related Clonal Hematopoiesis Driver Gene Ppm1d Promotes Inflammation and Non-Ischemic Heart Failure in Mice41
Sex Differences and Similarities in Valvular Heart Disease40
Diabetes Impairs Cellular Cholesterol Efflux From ABCA1 to Small HDL Particles40
Small Extracellular Vesicles From Brown Adipose Tissue Mediate Exercise Cardioprotection40
A Neuroligin Isoform Translated by circNlgn Contributes to Cardiac Remodeling40
MIR503HG Loss Promotes Endothelial-to-Mesenchymal Transition in Vascular Disease39
Advances in Lymphedema39
Aging Microbiota-Gut-Brain Axis in Stroke Risk and Outcome39
Infarct Collagen Topography Regulates Fibroblast Fate via p38-Yes-Associated Protein Transcriptional Enhanced Associate Domain Signals39
Cardiac Tissues From Stem Cells39
An Immuno-Cardiac Model for Macrophage-Mediated Inflammation in COVID-19 Hearts38
Live Imaging of Intracranial Lymphatics in the Zebrafish38
Gut Dysbiosis Promotes Preeclampsia by Regulating Macrophages and Trophoblasts38
Intracellular β 1 -Adrenergic Receptors and Organic Cation Transporter 3 Mediate Phospholamban Phosphorylation to Enhance Cardiac Contractility38
Vascular Dysfunction of COVID-19 Is Partially Reverted in the Long-Term37
Adrenergic Ca V 1.2 Activation via Rad Phosphorylation Converges at α 1C I-II Loop37
Multi-Omics Approaches to Define Calcific Aortic Valve Disease Pathogenesis37
Lipid Profiles and Heart Failure Risk37
CaMKII Serine 280 O-GlcNAcylation Links Diabetic Hyperglycemia to Proarrhythmia37
Immunometabolic Endothelial Phenotypes: Integrating Inflammation and Glucose Metabolism37
Hyperglycemia Induces Myocardial Dysfunction via Epigenetic Regulation of JunD36
Treatment of Obesity in Mitigating Metabolic Risk35
Reverse Remodeling With Left Ventricular Assist Devices35
Targeting CaMKII-δ9 Ameliorates Cardiac Ischemia/Reperfusion Injury by Inhibiting Myocardial Inflammation35
Brain Hypoxia Is Associated With Neuroglial Injury in Humans Post–Cardiac Arrest35
Tamoxifen-Activated CreERT Impairs Retinal Angiogenesis Independently of Gene Deletion35
Dll4 Suppresses Transcytosis for Arterial Blood-Retinal Barrier Homeostasis35
MCUb Induction Protects the Heart From Postischemic Remodeling35
Association Between Atrial Fibrillation and Sudden Cardiac Death35
Platelets and COVID-1934
atg7 -Based Autophagy Activation Reverses Doxorubicin-Induced Cardiotoxicity34
Reduced Platelet miR-223 Induction in Kawasaki Disease Leads to Severe Coronary Artery Pathology Through a miR-223/PDGFRβ Vascular Smooth Muscle Cell Axis34
Machine Learned Cellular Phenotypes in Cardiomyopathy Predict Sudden Death34
Exercise Regulates MicroRNAs to Preserve Coronary and Cardiac Function in the Diabetic Heart34
Novel Methods for Quantification of Vasodepression and Cardioinhibition During Tilt-Induced Vasovagal Syncope34
GLP1R Attenuates Sympathetic Response to High Glucose via Carotid Body Inhibition33
Generation of Vascular Smooth Muscle Cells From Induced Pluripotent Stem Cells33
Preclinical Models of Cancer Therapy–Associated Cardiovascular Toxicity: A Scientific Statement From the American Heart Association33
Association of Habitual Physical Activity With Cardiovascular Disease Risk33
Illuminating the Mechanisms Underlying Sex Differences in Cardiovascular Disease33
Nutrition, Thrombosis, and Cardiovascular Disease33
The Latest in Animal Models of Pulmonary Hypertension and Right Ventricular Failure33
Myeloid Cell PKM2 Deletion Enhances Efferocytosis and Reduces Atherosclerosis33
ATAC-Seq Reveals an Isl1 Enhancer That Regulates Sinoatrial Node Development and Function33
How Will Machine Learning Inform the Clinical Care of Atrial Fibrillation?33
Modulation of Mammalian Cardiomyocyte Cytokinesis by the Extracellular Matrix33
Eosinophils Protect Mice From Angiotensin-II Perfusion–Induced Abdominal Aortic Aneurysm32
Randomized Trial of Etelcalcetide for Cardiac Hypertrophy in Hemodialysis32
Gut Microbiota-Associated Activation of TLR5 Induces Apolipoprotein A1 Production in the Liver32
COVID-19, Myocarditis and Pericarditis32
Device Therapy of Hypertension32
Loss of Hepatic Angiotensinogen Attenuates Sepsis-Induced Myocardial Dysfunction31
Effects of Atrial Fibrillation on the Human Ventricle31
Genomic Characterization of Endothelial Enhancers Reveals a Multifunctional Role for NR2F2 in Regulation of Arteriovenous Gene Expression31
Periostin31
Mitochondria Do Not Survive Calcium Overload During Transplantation31
DC ENaC-Dependent Inflammasome Activation Contributes to Salt-Sensitive Hypertension31
Sorting Nexin 10 Mediates Metabolic Reprogramming of Macrophages in Atherosclerosis Through the Lyn-Dependent TFEB Signaling Pathway31
Faecalibacterium prausnitzii Attenuates CKD via Butyrate-Renal GPR43 Axis30
Hypokalemia Promotes Arrhythmia by Distinct Mechanisms in Atrial and Ventricular Myocytes30
Butyrate-Rich Diets Improve Redox Status and Fibrin Lysis in Behçet’s Syndrome30
Somatic Mutations in Cardiovascular Disease30
Heart Failure With Targeted Cancer Therapies30
Identification of Functional Variant Enhancers Associated With Atrial Fibrillation30
CaMKIIδC Drives Early Adaptive Ca 2+ Change and Late Eccentric Cardiac Hypertrophy30
Novel Mechanisms of Exosome-Mediated Phagocytosis of Dead Cells in Injured Heart30
Epigenomes of Human Hearts Reveal New Genetic Variants Relevant for Cardiac Disease and Phenotype29
Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atherosclerosis29
Sex-Specific Cardiovascular Risks of Cancer and Its Therapies29
NLRP3 Inflammasome Mediates Immune-Stromal Interactions in Vasculitis29
Niacin Attenuates Pulmonary Hypertension Through H-PGDS in Macrophages29
Cardiovascular Disease Screening in Women: Leveraging Artificial Intelligence and Digital Tools29
Genetic Dissection of a Super Enhancer Controlling the Nppa-Nppb Cluster in the Heart29
Targeting Myeloid-Specific Integrin α9β1 Improves Short- and Long-Term Stroke Outcomes in Murine Models With Preexisting Comorbidities by Limiting Thrombosis and Inflammation29
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