OOIR: Observatory of International Research

Papers

(The H4-Index of Circulation Research is 80. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System	1373
Association of Inpatient Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers With Mortality Among Patients With Hypertension Hospitalized With COVID-19	743
Obesity Phenotypes, Diabetes, and Cardiovascular Diseases	697
Epidemiology of Atrial Fibrillation in the 21st Century	608
COVID-19 and the Heart	519
Cardiac Energy Metabolism in Heart Failure	436
Metabolic Inflammation and Insulin Resistance in Obesity	429
The Emerging Threat of (Micro)Thrombosis in COVID-19 and Its Therapeutic Implications	428
Gut Microbiota and Cardiovascular Disease	423
Interleukin-1 and the Inflammasome as Therapeutic Targets in Cardiovascular Disease	391
Loss of Cardiac Ferritin H Facilitates Cardiomyopathy via Slc7a11-Mediated Ferroptosis	374
Epidemiology of Heart Failure	370
Platelets Can Associate With SARS-CoV-2 RNA and Are Hyperactivated in COVID-19	360
Cardiomyocyte Maturation	346
SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE 2	289
Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics	281
Basic Mechanisms of Diabetic Heart Disease	275
Gut Microbiota–Derived Short-Chain Fatty Acids Promote Poststroke Recovery in Aged Mice	255
Obesity, Adipose Tissue and Vascular Dysfunction	248
Basic and Therapeutic Aspects of Angiogenesis Updated	246
Interleukin-6 Signaling and Anti-Interleukin-6 Therapeutics in Cardiovascular Disease	234
COVID-19 and Cardiovascular Disease	226
Molecular Basis of Atrial Fibrillation Pathophysiology and Therapy	219
Arterial Stiffness and Cardiovascular Risk in Hypertension	216
Social Determinants of Cardiovascular Disease	210

Meta-Analysis of Leukocyte Diversity in Atherosclerotic Mouse Aortas	202
Epidemiology of Peripheral Artery Disease and Polyvascular Disease	200
Neutrophil Extracellular Traps Participate in Cardiovascular Diseases	197
Post-Stroke Cognitive Impairment and Dementia	194
Sex as a Biological Variable in Atherosclerosis	191
Targeting Mitochondria-Inflammation Circuit by β-Hydroxybutyrate Mitigates HFpEF	189
Oxidative Stress and Hypertension	188
Myofibroblasts and Fibrosis	182
In Situ Expansion, Differentiation, and Electromechanical Coupling of Human Cardiac Muscle in a 3D Bioprinted, Chambered Organoid	172
Adiponectin, Leptin and Cardiovascular Disorders	156
The Impact of Sex and Gender on Stroke	153
Atrial Myocyte NLRP3/CaMKII Nexus Forms a Substrate for Postoperative Atrial Fibrillation	151
GSDMD-Mediated Cardiomyocyte Pyroptosis Promotes Myocardial I/R Injury	143
From Systemic Inflammation to Myocardial Fibrosis	134
Regulatory T Cells License Macrophage Pro-Resolving Functions During Atherosclerosis Regression	128
Clonal Hematopoiesis–Driver DNMT3A Mutations Alter Immune Cells in Heart Failure	127
SIRT6 Protects Smooth Muscle Cells From Senescence and Reduces Atherosclerosis	126
SARS-CoV-2 Initiates Programmed Cell Death in Platelets	125
Celastrol Attenuates Angiotensin II–Induced Cardiac Remodeling by Targeting STAT3	124
Arterial Stiffness Preceding Diabetes	117
Dynamics of Cardiac Neutrophil Diversity in Murine Myocardial Infarction	114
Pathophysiology of Hypertension	113
Intracellular and Intercellular Aspects of Macrophage Immunometabolism in Atherosclerosis	113
Cerebral Hemorrhage: Pathophysiology, Treatment, and Future Directions	111
Pregnancy and Reproductive Risk Factors for Cardiovascular Disease in Women	109
Genetics of Atrial Fibrillation in 2020	109
Hypertension in Low- and Middle-Income Countries	104
Reactive Oxygen-Forming Nox5 Links Vascular Smooth Muscle Cell Phenotypic Switching and Extracellular Vesicle-Mediated Vascular Calcification	102
The Tumor-Suppressive Human Circular RNA CircITCH Sponges miR-330-5p to Ameliorate Doxorubicin-Induced Cardiotoxicity Through Upregulating SIRT6, Survivin, and SERCA2a	102
Role of the GLUT1 Glucose Transporter in Postnatal CNS Angiogenesis and Blood-Brain Barrier Integrity	102
S100A9 Links Inflammation and Repair in Myocardial Infarction	100
Polygenic Scores to Assess Atherosclerotic Cardiovascular Disease Risk	96
NAD ⁺ Repletion Reverses Heart Failure With Preserved Ejection Fraction	96
Hypertension	95
Hematopoiesis and Cardiovascular Disease	95
Inflammation, Infection and Venous Thromboembolism	94
Immune Cells and Immunotherapy for Cardiac Injury and Repair	93
Atherogenic Lipoprotein(a) Increases Vascular Glycolysis, Thereby Facilitating Inflammation and Leukocyte Extravasation	92
Single-Cell Analysis of Blood-Brain Barrier Response to Pericyte Loss	91
Cardiac Resident Macrophages Prevent Fibrosis and Stimulate Angiogenesis	90
BET Epigenetic Reader Proteins in Cardiovascular Transcriptional Programs	88
Molecular Genetic Basis of Hypertrophic Cardiomyopathy	87
Lymphatic Malformations: Genetics, Mechanisms and Therapeutic Strategies	87
Platelet and Vascular Biomarkers Associate With Thrombosis and Death in Coronavirus Disease	86
Genetic Basis and Therapies for Vascular Anomalies	85
Klotho Deficiency Causes Heart Aging via Impairing the Nrf2-GR Pathway	85
The Gut Microbiome in Hypertension	85
Metabolomics and Proteomics in Type 2 Diabetes	83
AP-1 Contributes to Chromatin Accessibility to Promote Sarcomere Disassembly and Cardiomyocyte Protrusion During Zebrafish Heart Regeneration	83
miR-128-3p Is a Novel Regulator of Vascular Smooth Muscle Cell Phenotypic Switch and Vascular Diseases	83

Cerebral Cavernous Malformation: From Mechanism to Therapy	82
Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension	81
Gene Therapy for the Heart Lessons Learned and Future Perspectives	81
Single Cell RNA Sequencing in Atherosclerosis Research	80
Hyperglycemia Acutely Increases Cytosolic Reactive Oxygen Species via O -linked GlcNAcylation and CaMKII Activation in Mouse Ventricular Myocytes	80