OOIR: Observatory of International Research

Papers

(The TQCC of Chemistry of Heterocyclic Compounds is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
The synthesis and antitubercular activity of 4,5-dihydro-1H-pyrazole derivatives with a basic epoxybenzo[7,8]oxocine framework	26
Method for the synthesis of chromenopyrimidine-fused azoles by copper-catalyzed intramolecular hetero-Diels–Alder reaction	16
Mechanochemical synthesis of halogenated heterocyclic compounds	16
Structural and chemical reactivity insights of a benzimidazolidinone-based N-heterocycle: a multiapproach quantum-chemical study	13
An AgOAc-catalyzed reaction of 3-nitro-2H-chromenes with ethyl diazoacetate: an efficient one-pot synthesis of ethyl 3,4-dihydrochromeno[3,4-c]pyrazole-1-carboxylates	12
An intramolecular Diels–Alder reaction in the synthesis of N-aroyl-3a,6-epoxyisoindole-2-carbothioamides	12
Synthesis and neuroprotective activity of a (–)-cytisine-isoflavone conjugate	11
3-Cyanothiete 1,1-dioxide: synthesis and cycloaddition reactions	10
A simple method for the synthesis of isoindoline derivatives	10
Stereoselective synthesis of tetrahydropyrimidin-2(1H)-ones (minireview)	10
Melaminium dihydrogenpyrophosphate: synthesis, crystal packing, Hirshfeld surface analysis, and reactivity mapping: a combined experimental and theoretical study	9
A MEDT study of the mechanism and selectivity of the hetero-Diels–Alder reaction between 3-benzoylpyrrolo[1,2-c][1,4]-benzoxazine-1,2,4-trione and vinyl acetate	9
Unexpected ANRORC rearrangement in pyran ring	9
A systematic theoretical approach on using some heteroatom-decorated BC10N nanosheets for drug delivery of carmustine	9
Halogenated pyrrole-2-carbaldehydes. 2. Synthetic potential and some application aspects	9
Tetrahydroazepines with an annulated five-membered heteroaromatic ring	9
Synthesis, structure, and biological activity of 4-hetaryl-2-pyrrolidones containing a pyrazole ring	9
Synthetic approaches toward 2,3-dihydroquinazolinones (microreview)	9
Recent progress in the synthesis of nitroisoxazoles and their hydrogenated analogs via [3+2] cycloaddition reactions (microreview)	8
Synthesis of N,N-dimethyl-3,5-dinitro-1H-pyrazol-4-amine and its energetic derivatives as promising melt-castable explosives	8
A method for the synthesis of spiro-1,3,4-thiadiazolines	8
Selenium-containing azoles: synthesis and possibilities of application	8
Synthesis of benzo[f]indole-4,9-dione derivatives by multicomponent reactions (microreview)	7
Synthesis of 5,11-dialkyl-5,6,11,12-tetrahydro-6,12-epoxydibenzo[b,f][1,5]diazocines from 2-alkylaminobenzaldehydes	7
Computational mechanistic study of the Diels–Alder reaction between the N-substituted exocyclic oxazolidin-2-one diene and symmetric bis-chalcone	6

Synthesis of pyrrolizidine derivatives (microreview)	6
Recent synthesis of 1,2- and 2,3-dihydrophosphetes	6
A novel method for the synthesis of 2-arylquinolin-4(1H)-ones	6
Hexamethyldisilazane as a versatile organosilicon reagent for the synthesis of heterocycles (microreview)	6
Methods for the preparation of 2-nitrobenzofurans	6
Three-component one-pot synthesis of thiazolo[5,4-e]indole derivatives	6
The synthesis of salts of five-membered heterocyclic compounds based on N-containing cations/anions (microreview)	6
Intramolecular Friedel–Crafts alkylation by electrochemical carbenium ion generation	6
Coumarin-based homoisoflavonoids as precursors in the synthesis of 8-heteroarylmethylcoumarins	6
A novel approach to obtain 3-amino-1-benzothiophene-2-carbonitriles	6
Cyclopent-4-ene-1,3-diones fused with heterocycles as promising anchor groups in non-fullerene acceptors (microreview)	6
Rational design, synthesis, and catalytic enantioselective derivatization of an achiral ansa-macrocycle	6
Characterization and structure analysis of triclinic γ-cyclodextrin hydrate methanol solvate	6
A simple method for the synthesis of diarylamines containing a nitroso group in the ortho position based on the SNH arylamination of 5-nitroisoquinoline	5
Nitrolysis of N-alkylurotropinium Salts	5
Chemo- and regioselective oxidation of substituted 2,3,4,9-tetrahydro-1H-carbazoles	5
Synthesis of 2H-[1,2]oxazino[3,4-c]quinoline-2,5(6H)-diones from 6-oxo-6H-1,2-oxazine-3-carboxylates	5
Exploring the factors controlling the mechanism and the high stereoselectivity of the polar [3+2] cycloaddition reaction of the N,N'-cyclic azomethine imine with 3-nitro-2-phenyl-2H-chromene. A molecu	5
Recent developments in the synthesis of spirobenzosultams (microreview)	5
Recent progress in the direct phosphorylation of parent heterocycles to construct phosphorylated heterocycles	5
The synthesis of 1-oxa-9-azaspiro[5.5]undecane derivatives and optimization of antituberculosis activity thereof	5
Recent progress in the synthesis of N7(N9)-alkyl(aryl)purines (microreview)	5
Synthesis of fluorinated six-membered nitrogen heterocycles using microwave irradiation	5
Bicyclic 1,2-oxazine 2-oxides as the discrete intermediates in the reactions between regioisomeric trimetylsilylcyclopentadienes and (2E)-2-nitro-3-phenylprop-2-enenitrile	5
A Structural Modification of Berberine Using CH Acids and Ethoxyethylenes Based on Them	5
A regioselective synthesis of 5-difluoromethyl- and 7-difluoromethyl-substituted pyrazolo[1,5-a]pyrimidines	4
Cs-containing BEA zeolite monoliths for 4-phenyl-1,3-dioxolan-2-one production from styrene epoxide and carbon dioxide in flow reactors	4
Influence of bicyclic anhydride structure on the outcome of the Castagnoli–Cushman reaction	4
Pyridine-2-selanyl chloride in the synthesis of condensed heterocycles (microreview)	4
A study of the reactivity of 2,4-diphenylfuran	4
Synthesis of tellurium-substituted azoles (microreview)	4
Synthesis and NMR spectra of [15N]indole	4
Stereochemical aspect of a Biginelli-like reaction involving cyclohexanone and 3-amino-1H-1,2,4-triazole	4
A synthesis of triacetyl-substituted 1,2,3,4-tetrahydropyridine by the reaction of 3-[(alkylsulfanyl)methyl]pentane-2,4-diones with aniline	4
Some properties of 1-hydroxy-1H-imidazole-2-carboxylic acid esters	4
Expanding the isoflavone, pyrazole, and oxazole chemical space through 2'-carboxamido-2-hydroxydeoxybenzoin precursors	4
A synthesis of novel 5-methylsulfanylazolo[1,5-a]pyrimidin-7(4H)-ones and investigation of their chemical and cytotoxic properties	4
The synthesis and antitumor activity of novel 1-alkyl-3-phenyland 3-alkyl-1-phenylimidazothiazolotriazines	4
Pseudopeptides based on nicotinic acid with 4-amidoxime unit	4
Synthesis of new class of trithiadiazacycloalkane 1,1-dioxides using Yb(Sm)-contaning catalysts and conformational analysis of the macroheterocycles	4
3-Spiroandrostene-substituted 1,3,4-thiadiazolines	4
[2+1] Cycloaddition reaction of α-atlantone with m-CPBA in the light of experimental and MEDT quantum-chemical study	4
Analgesic and Antidepressant Activity of 8-Substituted Harmine Derivatives	4
A regioselective synthesis of imidazothiazolotriazines based on the cyclization of imidazotriazinethiones with phenacyl bromides	4
The synthesis of ortho-stilbazoles (2-styrylpyridines) (microreview)	4
Unveiling the exclusive stereo and site selectivity in [3+2] cycloaddition reactions of a tricyclic strained alkene with nitrile oxides from the molecular electron density theory perspective	4
Proton- and iodine-induced cyclization of 2-(pent-4-en-1-yl)quinazolin-4(3H)-ones: synthesis of pyrrolo[2,1-b]quinazolinone and pyrido[1,2-a]quinazolinone derivatives	4
Synthetic approaches to phosphonylpyridazines: an overview	4
Quantum evaluation of novel epoxides: molecular docking, dynamics simulation, pharmacokinetics, stereoselectivity, and mechanistic insights into cis-himachalone and cis-himachalol epoxidation	4
Di-, tetra-, and perhydropyrrolo[1,2-a]imidazoles: The Methods of Synthesis and Some Aspects of Application	4

Synthesis of isoxazolo[4,5-b]pyridine derivatives (microreview)	4
Synthesis of alkenyl- and alkynyloxazoles and –oxazolines using tosylmethyl isocyanide as a key building block (microreview)	4
A General Approach to 4-unsubstituted and 4-alkyl-substituted 5-acyl-1,2,3,4-tetrahydropyrimidine-2-thiones(ones) via α-(thio)ureidoalkylation of 1,3-diketones or β-oxoesters	4
General methods for the synthesis of styrylpyridinium salts (microreview)	4
Synthesis of optically active 5-thioxotetrahydro-5H-oxazolo[3,2-c]pyrimidin-2(3H)ones	4
[3+3] Annulation of diethyl 2,3-dicyanofumarate and cyclic 1,3-dicarbonyl compounds: synthesis of fused diethyl 2-amino-4-cyano-4H-pyran-3,4-dicarboxylates	4
Divergent synthesis of 1,5-benzodiazepines and benzimidazoles via a BiCl3-catalyzed one-pot condensation–cyclization process	3
Synthesis and modulatory activity of 3-acetyl-7-(benzofuran-5-carbonyl)-1,5-dimethyl-3,7-diazabicyclo[3.3.1]nonan-9-one on AMPA receptors	3
Fused chiral azaheterocycles based on monosubstituted ferrocenes	3
Tandem Synthesis of Novel thiazole-substituted pyrrolo[1,2-d][1,2,4]triazin-4(3H)-one Derivatives and their Theoretical Pharmacokinetic Profiles	3
Hydrated imidazoline ring expansion reaction in 2,3-dihydro-9H-dibenzo[b,f]imidazo-[2,1-d][1,5]oxazocinone derivatives	3
Schizocommunin-inspired heterocyclic hybrid molecules	3
Catalytic reactions of epoxides and aziridines with carbon dioxide in the presence of salen-type complexes of 3d metals	3
Multicomponent synthesis of 1,5,6,7-tetrahydro-4H-indol-4-one derivatives	3
5-Chloro-4-[(thiazolidin-5-ylidene)methyl]pyrrole-3-carboxylates and carboxylic acids: synthesis, recycling, and antimicrobial activity	3
Sulfo-Biginelli reaction: an insight into interaction between sulfamides and enolizable ketones	3
A three-component cycloaddition of alkyl trifluorodiazoethane for the synthesis of trifluoromethylated isoxazolines	3
Synthesis of polysubstituted furan-3(4)-carboxylates (microreview)	3
[Difluoro(pyridinyl)methyl]phosphonates	3
Synthesis and structure of 3-substituted 1,5-dinitro-1,3,5-triazepanes	3
The Chemo- and Regioselectivity of the Cyclization of Thiosemicarbazides with Haloacetic Acids and their Derivatives	3
Preparative synthesis of polysubstituted 4-(5-arylisoxazol-3-yl)-1,4-dihydropyridines and -pyridines	3
Synthesis of functionalized polyhalogenated thiophene derivatives	3
New oxazole to oxazole recyclization	3
The synthesis and antiproliferative activity of isatin-7-sulfonamides	3
The reactions of arylazasydnones with S- and O-nucleophiles	3
Highly diastereoselective synthesis of pyridinium-substituted piperidin-2-ones from pyridinium ylides, aldehydes, Michael acceptors, and ammonium acetate	3
The synthesis of 3-nitro-4H-benzo[h]chromenes	3
A Regioselective Synthesis of 5-chloro-1-vinyl- and 3-alkenyl-5-chloro-1H-pyrazoles	3
Approaches to the synthesis of thiazolo[3,2-a]pyridines (microreview)	3
5-Arylmethylidene-2-iminothiazolidin-4-ones in the synthesis of novel dispiro-fused oxindolepyrrolidineiminothiazolidinones	3
Synthesis of β-vinyl-substituted 4H-chromenes and [4+2] cycloaddition reactions involving them	3
Recent advances in the application of Meerwein arylation for the synthesis of complex heterocycles at the Ivan Franko National University of Lviv (microreview)	3
Hydroarylation of carbon–carbon double bond of furanic conjugated enones by arenes under superelectrophilic activation: synthesis and evaluation of antimicrobial activity of novel furan derivatives	3
Synthesis of sulfolanopyranochromenones by the reaction of 2-benzylidene-3-methyl-4-nitro-2,5-dihydrothiophene 1,1-dioxides with 4-hydroxycoumarin	3
The synthesis and study of carbonic anhydrase activity of sulfonamide-containing dibenzo[1,4]thiazepines	3
The synthesis and study of antimicrobial activity of 5-oxo-1-(thiazol-2-yl)pyrrolidine-3-carboxylic acids	3
Synthesis of 6,7-dihydro-5H-benzo[c]-1,2,4-triazolo[3,4-a]azepines and 6,7-dihydro-5H-benzo[c]tetrazolo[5,1-a]azepines	3
Ring expansion strategy to access functionalized 2-oxazolines (microreview)	3
The reactions of electron-deficient 1Н-benzo[f]chromenes with 2,3-dimethylbenzothiazol-3-ium iodide	3
Synthesis of 2-arylquinazolines by Chan–Evans–Lam coupling of 2-formylphenylboronic acids with amidines	3
Conformationally restricted hydantoins derived from bridgehead functionalized camphorquinones	3
New approaches to the modification of chemical structure and photophysical properties of BODIPY dyes	3
Investigation of the solvent effect, regioselectivity, and the mechanism of the cycloaddition reaction between 2-chlorobenzimidazole and benzonitrile oxide	3
Modern approaches to the synthesis of phenazine derivatives (microreview)	3
The synthesis of N-substituted 2-amino-1,4,5,6-tetrahydropyrimidines from isocyanates	3
In silico Study of Conjugated Nitrogen Heterocycles Affinity in their Biological Complexes	3
Synthesis and Chemical Transformations of 2-imino-2,5-dihydrofurans	3
An unexpected route of alkylation of 7-substituted (dinitro)([1,2,4]triazolo[4,3-a][1,3,5]triazin-5-yl)methanides with allyl and benzyl bromide	3
A sequence of acylamination and acylation reactions in polyphosphoric acid – a novel approach to the Friedländer synthesis of 2-arylquinolines	3
The synthesis of fluorescent boron difluoride hydrazone (BODIHY) dyes (microreview)	3
Transition-metal-catalyzed carbonylation of C(sp2)–H bonds with CO2 to generate heterocyclic compounds (microreview)	3
Parent 5(7)-azachromones and their partially hydrogenated derivatives: synthesis and physicochemical properties	3