OOIR: Observatory of International Research

Papers

(The TQCC of Chemistry of Heterocyclic Compounds is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-02-01 to 2025-02-01.)

Article	Citations
Biologically active compounds and drugs in the tetrazole series	42
A study of atypical reaction of methyl (triphenylphosphoranylidene)-acetate with 3a-substituted bicyclic β-keto-γ-sultams	40
Imidazol-5-one-based donor–acceptor cyclopropanes in reaction with C=S dipolarophiles	39
Pyridine-2-selanyl chloride in the synthesis of condensed heterocycles (microreview)	35
A photochemical synthesis of substituted dihydroimidazo[1,2-a]pyridin-3(2H)-ones	22
Thematic issue “Chemistry of polyheteroatomic heterocyclic systems”	17
Modern approaches to the synthesis of phenazine derivatives (microreview)	16
Unexpected products of the reaction of purine nucleic base perchlorates with acetylacetone causing single-strand breaks in the DNA molecule	16
Cyclic Isothiourea in Drug Design	14
Method for the synthesis of chromenopyrimidine-fused azoles by copper-catalyzed intramolecular hetero-Diels–Alder reaction	13
Pseudopeptides based on nicotinic acid with 4-amidoxime unit	13
Analgesic and Antidepressant Activity of 8-Substituted Harmine Derivatives	13
Phosphazene superbase mediated cyclization and annulation reactions of functionalized alkynes for the synthesis of heterocyclic compounds	11
Structural characterization of products arising from methylsulfanyl group oxidation in pyrimidine derivatives using 13C NMR spectroscopy	11
Unexpected conversion of 4-oxo-4H-chromene-2-carboxylic acid to 2-(1,3-benzothiazol-2-yl)-4H-chromen-4-one and spiro[1,4-benzothiazine-2,2'-chromene]-3,4'(3'H,4H)-dione	11
Reactions of Quinolinecarbaldehydes with Arenes under Superelectrophilic Activation. NMR and DFT Studies of Dicationic Electrophilic Species	10
Synthesis of novel pyrimido[4,5-d]pyrimidine derivatives from 5-acetyl-4-aminopyrimidines	10
Approaches to the synthesis of thiazolo[3,2-a]pyridines (microreview)	10
A new approach to the synthesis of 17-pyrazolylandrostane	10
Nina Nikolaevna Makhova (31.07.1938–22.06.2021)	9
The synthesis of ethyl 2-amino-1-(aryl)-5-(arylcarbamoyl)-6-oxo-1,6-dihydropyridine-3-carboxylates	9
Unsaturated carboxylic acids in the one-pot synthesis of novel derivatives of 3,4-dihydro-2H-thiopyran	9
Synthesis and neuroprotective activity of a (–)-cytisine-isoflavone conjugate	9
Recent methods in the synthesis of chromeno[2,3-d]pyrimidines	9
Synthesis of 2,3-dihydro-1,4-benzoxathiine derivatives	8

Synthesis of julolidine derivatives via SnCl4-promoted spirocyclization of (1-alkyltetrahydroquinolin-8-yl)methylidene-1H-imidazol-5(4H)-ones	8
Synthesis of sulfolanopyranochromenones by the reaction of 2-benzylidene-3-methyl-4-nitro-2,5-dihydrothiophene 1,1-dioxides with 4-hydroxycoumarin	8
Synthesis of sulfolanooctahydrochromenones from 2-benzylidene-3-methyl-4-nitro-2,5-dihydrothiophene 1,1-dioxides	7
Recent advances in the application of Meerwein arylation for the synthesis of complex heterocycles at the Ivan Franko National University of Lviv (microreview)	7
The synthesis of 3-nitro-4H-benzo[h]chromenes	7
Synthesis and Chemical Transformations of 2-imino-2,5-dihydrofurans	7
Alkaloid-like annulated pyrano[4,3-b]pyrroles: antiviral activity and hydrolysis	7
Synthesis and NMR spectra of [15N]indole	7
The effect of substituents on carbon–carbon double bond isomerization in heterocyclic hydrazine derivatives	7
The synthesis of novel 1-hetarylmethylidene-4-sulfanylfuro-[3,4-c]pyridin-3(1H)-ones	7
A sequence of acylamination and acylation reactions in polyphosphoric acid – a novel approach to the Friedländer synthesis of 2-arylquinolines	7
In silico Study of Conjugated Nitrogen Heterocycles Affinity in their Biological Complexes	7
Pyrazoles, isoxazoles, and 1,2,3-triazoles as analogs of the natural cytostatic combretastatin A-4: efficient routes of synthesis, tubulin inhibition, and cytotoxicity	6
Thematic issue “Cycloaddition reactions: recent progress”	6
Synthetic Methods toward Phosphacoumarins (microreview)	6
An AgOAc-catalyzed reaction of 3-nitro-2H-chromenes with ethyl diazoacetate: an efficient one-pot synthesis of ethyl 3,4-dihydrochromeno[3,4-c]pyrazole-1-carboxylates	6
Recent developments in the synthesis of piperazines (microreview)	6
Methods for the synthesis of imidazo[2,1-b][1,3]thiazines, their annulated and hydrogenated analogs	6
Chemosensors based on 5-ethylidene-substituted barbituric acid derivatives (microreview)	6
Synthesis of functionalized 1-methylchromeno[3,4-b]pyrrol-4(3H)-ones via the Barton–Zard reaction starting from pseudonitrosites	6
The Diels–Alder reaction in the synthesis of fused heterocyclic aromatic compounds	6
Synthesis and Antiviral Activity of N-Heterocyclic Hydrazine Derivatives of Camphor and Fenchone	6
Acenaphthenequinone-Based Stabilized Azomethine Ylides in (3+2) Cycloaddition Reactions with 1,5-diarylpent-4-ene-1,3-diones	6
Metal oxides in multicomponent synthesis of heterocycles	6
Synthesis of C3h-symmetric benzotripyrrole derivatives as monomers for organic frameworks	6
Synthesis of 2H-pyrano[3,2-g]quinolin-2-ones containing a pyrimidinone moiety and characterization of their anticoagulant activity via inhibition of blood coagulation factors Xa and XIa	6
Microwave synthesis of triterpenoid-annulated imidazo[1,2-a]pyridines	6
One-pot transformations of tetracyanocyclopropanes into highly functionalized pyridines	6
A formal [4+1] cycloaddition of dimethoxycarbene to 3-perfluoroacyl-4H-chromenes: the synthesis of areno-condensed 7,7a-dihydro-4H-furo[3,4-b]pyrans	6
Regioselective [3+2] cycloaddition of nitrile oxides to 1Н-pyrrole-2,3-diones: synthesis of spiro[pyrroledioxazoles]	6
Synthesis of isomeric 4-(N-methyltetrazolylamino)-2-phenyl-4H-thiopyrano[2,3-b]quinoline-3-carbaldehydes and 4-hydroxy-2-phenyl-4H-thiopyrano[2,3-b]quinoline-3-carbaldehyde based on tandem thiol-Micha	5
The synthesis and antitubercular activity of 4,5-dihydro-1H-pyrazole derivatives with a basic epoxybenzo[7,8]oxocine framework	5
Reactivity of heterocyclic α-aminomethylsilanes with alcohols	5
Syntheses of quinolines and their derivatives from α,β-unsaturated aldehydes	5
Toward unsymmetrical 2,6-bistriazolylpurine nucleosides	5
Recent advances on heterocyclic compounds with antiviral properties	5
Synthesis of imidazo[2,1-b]thiazol-5-amines using Groebke–Blackburn–Bienaymé multicomponent reaction (microreview)	5
Recent methods for the synthesis of fused pyrazolo[3,4(4,3)-d]thiazoles and pyrazolo[3,4(4,3)-d][1,4]thiazines (microreview)	5
Electrophilically activated nitroalkanes in the synthesis of substituted 1,3,4-oxadiazoles from amino acid derivatives	5
[Difluoro(pyridinyl)methyl]phosphonates	5
Isomerization and changes of the properties of spiropyrans by mechanical stress: advances and outlook	5
Mechanochemical synthesis of halogenated heterocyclic compounds	5
Three-component synthesis of 2-acyl-2,3-dihydro-4H-thiochromeno[4,3-b]furan-4-ones and their reductive rearrangement into 4H,5H-thiochromeno[4,3-b]pyran-5-ones	5
An overview of the synthetic routes toward [1, 2, 4]triazolo[3,4-b][1,3,4]thiadiazoles (microreview)	5
Asymmetric synthesis of pyroglutamic acids via Ni(II) complex methodology	5
Synthesis and fungicidal activity of novel 6H-benzimidazo[1,2-c][1,3]benzoxazin-6-ones	5
Discovery of indole-3-acetic acid derivatives containing 1,3,4-thiadiazole thioether and amide moieties as novel antibacterial agents	5
An azo coupling of berberine derivatives: an experimental and quantum-chemical study	5
Intramolecular Diels–Alder reaction in the synthesis of 5-arylisoxazolylmethyl- and 4,5-dichloroisothiazolylmethyl-3a,6-epoxyisoindol-3-ones	5
A simple method for the synthesis of isoindoline derivatives	5

New methods for the synthesis of pyrrolo[1,2-x][1,4]diazepines and their (het)arene-annulated analogs (microreview)	5
Synthesis of new class of trithiadiazacycloalkane 1,1-dioxides using Yb(Sm)-contaning catalysts and conformational analysis of the macroheterocycles	5
5(4)-Aminopyrazoles as effective reagents in the synthesis of pyrazolo-annulated pyridines	5
An efficient one-pot synthesis of indolyl-4H-chromene derivatives	5
Synthesis and structural characterization of N,N',N'',N'''-tetrasubstituted cyclams	4
General methods for the synthesis of styrylpyridinium salts (microreview)	4
Synthesis and photophysical properties of the products of the reaction of 5-methyl-7-phenyl[1,3]oxazolo[5,4-b]pyridin-2(1H)-one with amino acids	4
An intramolecular Diels–Alder reaction in the synthesis of N-aroyl-3a,6-epoxyisoindole-2-carbothioamides	4
3-Nitro-1,2,4-triazol-5-one (NTO): High Explosive Insensitive Energetic Material	4
Synthesis of spiro[imidazole-4,3'-quinolin]ones from [2-(dimethylamino)benzylidene]-2-(methylsulfanyl)imidazolones	4
New methods for synthesis of 1-benzothiophene-3-carboxylic acid derivatives (microreview)	4
A simple and efficient synthesis of 1,3,6-trisubstituted pyrazoloquinolines via intramolecular cyclization – optimization studies	4
A study of the reactivity of 2,4-diphenylfuran	4
A three-component cycloaddition of alkyl trifluorodiazoethane for the synthesis of trifluoromethylated isoxazolines	4
Lewis acid catalyzed condensation of 2-aminohetarene N-oxides with N,N-dimethylformamide dimethyl acetal	4
Instructions to authors	4
Synthesis of cyclic aza-peroxides (microreview)	4
Stereoselective synthesis of tetrahydropyrimidin-2(1H)-ones (minireview)	4
Unexpected ANRORC rearrangement in pyran ring	4
Synthesis of chromeno[2,3-c]pyrrol-9(2H)-ones (microreview)	4
Synthesis of tellurium-substituted azoles (microreview)	4
PIDA-mediated C–N coupling cyclization for the synthesis of 3-aryl-1H-indazoles	4
The synthesis of indolizin-1-ylphosphonates via the reaction of ethynylphosphonates with pyridinium methylides	4
Heterocycles Based on 1-((Z)-1,4-dibromobut-2-en-2-yl)adamantane	4
Marina Abramovna Yurovskaya (1.03.1940–21.05.2021)	4
Synthesis and permethylation of methyl 5-(2-chloropyridin-3-yl)pentanoates	4
Synthesis and properties of heterocycle-containing podands	4
Density Estimation Method for Individual Compounds from X-Ray Diffraction Analysis of their Solvated Forms	3
Modern Methods for the Synthesis of Cyano-Substituted Bipyridine Derivatives (microreview)	3
The synthesis and cytotoxic activity of N-unsubstituted 3-aryl-4-(trifluoromethyl)-4H-spiro[chromeno[3,4-c]pyrrolidine-1,11'-indeno[1,2-b]quinoxalines]	3
Silver-assisted palladium-catalyzed one-pot synthesis of 3-(hetero)arylmethyl derivatives of imidazo[1,2-a]pyridines	3
SNH-Arylamination of 1-methylquinolin-2(1H)-one Nitro Derivatives	3
Progress in the synthesis of 3-fluorochromones (microreview)	3
Synthetic approaches toward 2,3-dihydroquinazolinones (microreview)	3
3-Cyanothiete 1,1-dioxide: synthesis and cycloaddition reactions	3
Selective synthesis of a novel glycoluril-based hybrid compound with high application potential	3
Synthesis of 3(5)-aryl-5(3)-pyrazolyl-1,2,4-oxadiazole nitro derivatives	3
A General Approach to 4-unsubstituted and 4-alkyl-substituted 5-acyl-1,2,3,4-tetrahydropyrimidine-2-thiones(ones) via α-(thio)ureidoalkylation of 1,3-diketones or β-oxoesters	3
Oxidative rearrangement of 3-aryl-1H-benzo[f]chromenes into 2-aroyl-1,2-dihydronaphtho[2,1-b]furans	3
Tandem Synthesis of Novel thiazole-substituted pyrrolo[1,2-d][1,2,4]triazin-4(3H)-one Derivatives and their Theoretical Pharmacokinetic Profiles	3
Transition metal catalyzed C–H functionalization of arylindazoles: assembly of highly functionalized heterocycles (microreview)	3
An efficient synthesis of (E)-3-[(dimethylamino)methylidene]furan-2(3H)-thiones and transamination reactions thereof	3
Three-component condensation of cyclic 1,3-dicarbonyl compounds, N-phenacylpyridinium salts, and isatins or aromatic aldehydes as a method for the synthesis of novel condensed 2-aroyl-2,3-dihydrofuran	3
Bu3P-mediated acylation of (E)-7-arylidene-6,7-dihydroindolizin-8(5H)-ones with acyl chlorides	3
Schizocommunin-inspired heterocyclic hybrid molecules	3
Novel Approach to the Synthesis of 3-amino-4-arylpyridin-2(1H)-one Derivatives	3
4-(N-Boc-amino)-1Н-1,2,3-triazolecarbothioamides in the synthesis of a new heterocyclic [1,2,3]triazolo[4,5-e][1,4]thiazepine system	3
A regioselective synthesis of imidazothiazolotriazines based on the cyclization of imidazotriazinethiones with phenacyl bromides	3
Porphyrins with Phenolic Fragments at the Periphery of the Macrocycle as Perspective Antioxidants, Cytoprotectors and Heavy Metal Scavengers	3
Synthesis of spiro[imidazole-4,3'-thiochroman]ones from [2-(benzylsulfanyl)benzylidene]imidazolones	3
A one-pot synthesis of 3-nitro-2H-thiopyrans and their selective reduction to 3-nitro-3,4-dihydro-2H-thiopyrans	3
Recyclization of N-arylitaconimides with carboximidamides – a novel efficient method for the synthesis of 2-(2-amino-6-oxo- 1,4,5,6-tetrahydropyrimidin-5-yl)acetanilides	3
Synthesis and SAR of phenylazoles, active against Staphylococcus aureus Newman	3
Synthesis of the First Dithiaaza-17-Crown-5 Ethers Containing Piperidin-4-One Subunit	3
A synthesis of carbonyl-substituted 4-aryl-4H-benzo[h]chromenes based on a three-component condensation of α-naphthol, aromatic aldehydes, and β-enaminones	3
Oxidative cyclization of 5-aryl-1-benzyl-1,2,3-triazoles bearing electron-rich aromatic groups: ortho/ortho and ortho/ipso coupling	3
Synthetic transformations of sesquiterpene lactones. Controllable synthesis of 11,13-dihydroisoalantolactone azides and 13-(1,2,3-triazolyl)eudesmanolides based on sesquiterpene lactones	3
Formation of 4-(het)aryl-3H-1,5-benzodiazepine-2-carboxylates from (het)aroylpyruvate esters and o-phenylenediamine	3
1-Aryl-4-(2-oxoalkylsulfanyl)-2,3(5H)-benzodiazepines: synthesis and thiophene ring annulation to 1,2-diazepine core	3
Tetrahydroazepines with an annulated five-membered heteroaromatic ring	3
[3+2] Annulation of 2-substituted 3-nitro-2H-chromenes with mercaptoacetaldehyde: stereoselective synthesis of tetrahydro-4H-thieno[3,2-c]chromen-3-ols	3
Synthetic application of oxiranecarbonitriles (microreview)	3
Synthesis of 1'-aryl-3''-(1H-benzotriazol-1-yl)-5',5'',6',6'',7',7a'-hexahydro-1'H,8''H-dispiro[indeno[1,2-b]quinoxaline-11,3'-pyrrolizine-2',7''-indolizin]-8''-ones via cycloaddition reaction	3
Cascade assembling of aldehydes and two molecules of dimedone into 4H-spiro[1-benzofuran-2,1'-cyclohexane]-2',4,6'-triones under column chromatography-free protocol at room temperature	3