Chemistry of Heterocyclic Compounds

Article	Citations
3-Nitro-1,2,4-triazol-5-one (NTO): High Explosive Insensitive Energetic Material	42
Recent advances on heterocyclic compounds with antiviral properties	40
Biologically active compounds and drugs in the tetrazole series	39
Antiviral nucleoside analogs	35
Good pyridine hunting: a biomimic compound, a modifier and a unique pharmacophore in agrochemicals	22
Isomerization and changes of the properties of spiropyrans by mechanical stress: advances and outlook	22
Antiviral activity of 1,2,4-triazole derivatives (microreview)	17
On the influence of weak intermolecular interactions on the molecular crystal density of 1,3,5-triazine trinitroalkyl derivatives	16
Synthetic strategies for pyrrolo[2,1-f][1,2,4]triazine: the parent moiety of antiviral drug remdesivir	14
Pyrimido[1,2-a]benzimidazoles: synthesis and perspective of their pharmacological use	14
Synthesis of biologically active derivatives of 2-aminobenzothiazole	14
The Dimroth Rearrangement in the Synthesis of Condensed Pyrimidines – Structural Analogs of Antiviral Compounds	13
Regioisomeric 3,5-di(nitropyrazolyl)-1,2,4-oxadiazoles and their energetic properties	13
2H-Azirines in medicinal chemistry	13
Synthesis of 5-arylmethylidene-3-(arylmethylideneamino)thiazolidine-2,4-diones via triazine ring cleavage of tetrahydroimidazothiazolotriazinediones and their reactions with azomethine ylides	12
Synthesis of novel 3-arylated 2-hydroxy-1,4-naphthoquinone derivatives via microwave-assisted three-component domino reaction and evaluation of their cytotoxic activity	11
Two approaches toward the regio- and stereoselective synthesis of N-unsubstituted 3-aryl-4-(trifluoromethyl)-4H-spiro-[chromeno[3,4-c]pyrrolidine-1,3'-oxindoles]	11
Spiropyrans: molecules in motion	11
Synthesis and analgesic activity of 1-[(1,2,3-triazol-1-yl)methyl]quinolizines based on the alkaloid lupinine	10
Synthesis and antiherpetic activity of novel purine conjugates with 7,8-difluoro-3-methyl-3,4-dihydro-2H-1,4-benzoxazine	10
Synthesis and antiviral activity of nonannulated tetrazolylpyrimidines	10
Photochemical synthesis of novel naphtho[1,2-b]benzofuran derivatives from 2,3-disubstituted benzofurans	9
Expanding the chemical space of 3(5)-functionalized 1,2,4-triazoles	9
Synthesis of five-membered heterocycles by [3+2] cycloaddition reactions of sulfur-containing 3,3,3-trifluoropropene derivatives	9
An efficient one-pot synthesis of indolyl-4H-chromene derivatives	9

3-Cyanoazolo[5,1-c][1,2,4]triazines: synthesis and antiviral activity	9
Unsaturated carboxylic acids in the one-pot synthesis of novel derivatives of 3,4-dihydro-2H-thiopyran	9
Synthesis of unsymmetrical cage phosphonates from heterocyclic systems based on 2H-1,2-benzoxaphosphinine	8
Novel Approach to the Synthesis of 3-amino-4-arylpyridin-2(1H)-one Derivatives	8
Modeling the binding of protoporphyrin IX, verteporfin, and chlorin e6 to SARS-CoV-2 proteins	8
Synthesis and Antiviral Activity of N-Heterocyclic Hydrazine Derivatives of Camphor and Fenchone	8
Reactions of β-Carbonyl-Substituted 4H-chromenes and 1H-benzo[f]Chromenes with 5-aminopyrazoles	8
Methods for the Preparation of 3-Nitrobenzofurans	7
Synthesis and antiviral activity of novel 3-substituted pyrazolinium salts	7
Multicomponent Reactions Based on In Situ Generated Isocyanides for the Construction of Heterocycles	7
Highly efficient phosphine-catalyzed routes to α-imidoacrylates and 2,3-diimidopropanoates	7
Novel purine conjugates with N-heterocycles: synthesis and anti-influenza activity	7
Synthesis of 3(5)-aryl-5(3)-pyrazolyl-1,2,4-oxadiazole nitro derivatives	7
Synthesis of new 2-substituted 6,8-dinitro[1,2,4]triazolo[1,5-a]pyridines	7
Regio- and Stereoselective 1,3-dipolar Cycloaddition of Azomethine Ylides Based on Isatins and (thia)proline to 3-nitro-2-(trifluoro(trichloro)methyl)-2H-chromenes: Synthesis and Cytotoxic Activity of	7
Nucleophilic Dearomatization of 3-nitrobenzofurans by the Action of 2-(1-arylethylidene)Malononitriles	7
Design, synthesis, and anti-breast-cancer activity evaluation of pyrrolo(pyrido)[2,3-d]pyrimidine derivatives	7
Synthesis of 2H-pyrano[3,2-g]quinolin-2-ones containing a pyrimidinone moiety and characterization of their anticoagulant activity via inhibition of blood coagulation factors Xa and XIa	7
Synthesis via the Mannich Reaction and Biological Activity of Novel Fluorinated Camptothecin Derivatives	6
Antiviral drug Triazavirin, selectively labeled with 2H, 13C, and 15N stable isotopes. Synthesis and properties	6
Synthesis, Cytotoxicity, and α-glucosidase Inhibitory Activity of Triterpenic and Sitosterol Tetrazole Derivatives	6
Conformations of saturated five-membered heterocycles evaluated by MP2 calculations	6
Antiviral Agents – Benzazine Derivatives	6
Construction and Characterization of 3,7-Dichloro-N-(2,6-Diethylphenyl)-N-(2-Propoxyethyl)Quinolone-8-Carboxamide: A Potential Novel Pesticide Compound	6
Synthesis and antiproliferative activity characterization of new imidazothiazolotriazine oxindolylidene derivatives containing various substituents in the oxindole ring	6
A three-component condensation of cyclic enamino ketones, phenylglyoxal hydrate, and ethyl cyanoacetate	6
Electrophilic Fluorination of Heterocyclic Compounds with NF Reagents in Unconventional Media	6
Synthesis and photophysical properties of 2-azolyl-6-piperidinylpurines	6
New methods for the synthesis of phosphono-δ-lactones (microreview)	6
Stepwise, zwitterionic course of hetero-Diels–Alder reaction between 1,2,4-triazine molecular systems and 2-cyclopropylidene-1,3-dimethylimidazoline	6
Three-component condensation of cyclic 1,3-dicarbonyl compounds, N-phenacylpyridinium salts, and isatins or aromatic aldehydes as a method for the synthesis of novel condensed 2-aroyl-2,3-dihydrofuran	6
Synthesis, X-ray and DFT Studies of 6-halo-3-(hydroxymethyl)cinnolin-4(1H)-ones	6
Synthesis, Biological Activity and Photophysical Studies of Ellipticine and its Derivatives: State of the Art	6
Microwave-assisted synthesis of pyrazolo[3,4-b]pyridine derivatives (microreview)	6
Benzobischalcogenadiazoles: synthesis and applications (microreview)	6
Regio- and stereoselectivity of [3+2] cycloaddition reactions between (Z)-1-(anthracen-9-yl)-N-methyl nitrone and analogs of trans-β-nitrostyrene on the basis of MEDT computational study	6
Highly diastereoselective four-component synthesis of polysubstituted 1,4,5,6-tetrahydropyridines	6
Synthesis and fungicidal activity of novel 6H-benzimidazo[1,2-c][1,3]benzoxazin-6-ones	6
Synthesis of tetrazole derivatives through conversion of amide and thioamide functionalities	6
Synthesis of novel γ-butyrolactone-based phenazine compounds via microwave-assisted multicomponent domino reactions	5
Synthesis of functionalized azolo(azino)quinazolines by electrophilic cyclization (microreview)	5
Formation of five- and six-membered nitrogen-containing heterocycles on the basis of hydrazones derived from α-dicarbonyl compounds (microreview)	5
Group-assisted purification chemistry principles to access highly substituted zwitterionic furans via fast, concise, and efficient one-pot three-component assembly	5
6-Nitro-4,7-dihydroazolo [1,5-a]pyrimidines: an alternative mechanism of formation and studies of alkylation	5
NaSCN–(NH4)2Ce(NO3)6 system in heterocycle thiocyanation: synthesis of novel highly potent broad-spectrum fungicides for crop protection	5
The Chemo- and Regioselectivity of the Cyclization of Thiosemicarbazides with Haloacetic Acids and their Derivatives	5
Synthesis of 3-Amino-6,7-Dihydroferroceno[a]Quinolizin-4-One Derivatives via the Reaction of 3,4-Dihydroferroceno[c]Pyridines with Azlactones	5
Quadruple Bond Forming Multicomponent Approach to 5-(3-chromenyl)-5H-chromeno[2,3-b]pyridines and Its Interaction with the Neuropeptide Y1 Receptor	5
Heterocycles Based on 1-((Z)-1,4-dibromobut-2-en-2-yl)adamantane	5
Facile Synthesis and Spectral Properties of Novel Isomeric Nitrile-Rich Bipyridine Derivatives	5

Synthesis of pyrroles from propargylamines and their derivatives: an update (microreview)	5
Synthesis and photophysical investigation of AIEgen dyes bearing quinoline and BODIPY scaffolds	5
Synthesis and application of haloisoxazoles	5
Palladium-catalyzed amino group arylation of 1,3-disubstituted 1H-pyrazol-5-amine based on Buchwald–Hartwig reaction	5
Synthesis of Novel 3-(Pyridin-4-yl)-1,2,4-Triazines, their Analogs and Study of the Activity Against Vaccinia Virus	5
Bromination of 3,4-dihydro-2H-thiopyran derivatives	5
Synthesis of 1,2-Dihydroisoquinoline-1-Carboxylates Under Cobalt Catalysis	5
Synthesis and Anticancer Activity of 11-azaartemisinin Derivatives Bearing 1,2,3-triazole Moiety	5
Alkaloid-like annulated pyrano[4,3-b]pyrroles: antiviral activity and hydrolysis	5
Synthesis of 3-Silylated 3-Sulfolenes from Propargylsilanes and their Reductive Desulfitation	5
Nitrolysis of N-alkylurotropinium Salts	5
Formation of Five- and Six-membered Oxygen-containing Heterocycles on the Basis of 1-halo-1-nitroalkenes	5
Sonochemical synthesis of 1',4'-dialkyl-1',4',5',6'-tetrahydropyrazino[2',3':1,9](C60-Ih)[5,6]fullerenes	5
Electrocatalytic tandem assembly of aldehydes with 2-thiobarbituric acid into 5,5'-(arylmethylene)bis(1,3-diethyl-2-thiobarbituric acids) and evaluation of their interaction with catalases	5
Synthesis, structure, and antiviral properties of novel 2-adamantyl-5-aryl-2H-tetrazoles	5
Coumarin synthesis via Pechmann condensation: toward a greener era (microreview)	5
Synthesis of novel isoxazole derivatives bearing kojic acid moiety and evaluation of their antimicrobial activity	5
Michael Adducts of Levoglucosenone with α-Ethoxycarbonyl- and α-Nitrocyclododecanones: Transformation into Chiral Macrolides	5
Synthesis of isoxazolylpyrrolones by three-component reaction of α-ketoglutaric acid or its diethyl ester with 3-amino-5-methylisoxazole and aromatic aldehydes	4
Highly functionalized pyrazolines from symmetric and asymmetric 1,2-disulfonylhydrazines: a combination of experimental and DFT perspectives	4
Synthesis of spiro[imidazole-4,3'-quinolin]ones from [2-(dimethylamino)benzylidene]-2-(methylsulfanyl)imidazolones	4
Recent developments in the synthesis of piperazines (microreview)	4
Electrocatalytic cascade approach to the synthesis of dihydro-2'H,3H-spiro[1-benzofuran-2,5'-pyrimidines]	4
A Structural Modification of Berberine Using CH Acids and Ethoxyethylenes Based on Them	4
Improved Synthesis and Thermochemical Properties of Amino- and Hydrazino-1,2,4,5-Tetrazines	4
A Beckmann rearrangement initiated by trifluoromethanesulfonic anhydride in the synthesis of compounds containing a new pyrazolo[3',4':5,6]pyrido[3,2-b]azepine heterocyclic system	4
Synthesis of azidopropargylamino-substituted 1,3,5-triazines – novel monomers for the production of energetic polymers	4
Synthesis of 2H-thiochromene derivatives (microreview)	4
Porphyrins with Phenolic Fragments at the Periphery of the Macrocycle as Perspective Antioxidants, Cytoprotectors and Heavy Metal Scavengers	4
A simple method for the synthesis of isoindoline derivatives	4
Synthesis and photophysical properties of the products of the reaction of 5-methyl-7-phenyl[1,3]oxazolo[5,4-b]pyridin-2(1H)-one with amino acids	4
Synthesis of 3-substituted tetrahydroindol-4-one	4
The Synthesis and Investigation of New Electroneutral Berberine Derivatives	4
Synthesis of new pyrido[2,3-d]pyrimidin-5-ones and pyrido[2,3-d]pyrimidin-7-ones functionalized at position 4 from 5-acetyl-6-amino-4-methylsulfanyl-2-phenylpyrimidine	4
Synthesis of new pyrido[2,3-d]pyrimidin-5-one, pyrido[2,3-d]pyrimidin-7-one, and pyrimidino[4,5-d][1,3]oxazine derivatives from 5-acetyl-4-aminopyrimidines	4
Modified synthesis and structural features of 2-benzylidene-4-nitro-2,5-dihydrothiophene 1,1-dioxides	4
Atom-efficient synthesis of hybrid molecules combining fragments of triazolopyrimidines and 3-ethoxycarbonyl-1-ethyl-6-fluoroquinolin-4(1H)-one through 1,2,3-triazole linker	4
Synthesis and SAR of phenylazoles, active against Staphylococcus aureus Newman	4
Synthesis of functionalized 1-methylchromeno[3,4-b]pyrrol-4(3H)-ones via the Barton–Zard reaction starting from pseudonitrosites	4
Cyclic Isothiourea in Drug Design	4
Unveiling the exclusive stereo and site selectivity in [3+2] cycloaddition reactions of a tricyclic strained alkene with nitrile oxides from the molecular electron density theory perspective	4
Ring-closure reactions of functionalized vinyl sulfonamides (microreview)	4
Multicomponent synthesis of nicotinic acid derivatives	4
о-Aminopyrimidine Aldehydes and Ketones: Synthesis and use as Precursors to Fused Pyrimidines	4
Imidazothiazoles and their Hydrogenated Analogs: Methods of Synthesis and Biomedical Potential	4
Synthesis of isoxazolo[4,5-b]pyridine derivatives (microreview)	3
Synthesis of substituted 2,5-dihydro-2,2'-bifurans	3
Tandem Synthesis of Novel thiazole-substituted pyrrolo[1,2-d][1,2,4]triazin-4(3H)-one Derivatives and their Theoretical Pharmacokinetic Profiles	3
The synthesis of 3-(het)aryl-6,7-dihydro-5H-[1,2,4]-triazolo[3,4-a][2]benzazepines	3
A three-component cycloaddition of alkyl trifluorodiazoethane for the synthesis of trifluoromethylated isoxazolines	3
[3+2] Cycloaddition reactions of 1-substituted 3,3,3-trifluoropropenes with isonitriles – synthesis of pyrroles and pyrrolines	3
Regio- and diastereoselective synthesis of N-substituted 2-acyl-3-aryl-3,5-dihydrofuro[3,2-c]pyridin-4(2H)-ones	3
One-pot synthesis of 1,5-benzodiazepine-2,3-dicarboxylates via three-component domino reactions in the presence of γ-Fe2O3@SiO2/Ce(OTf)3	3
An AgOAc-catalyzed reaction of 3-nitro-2H-chromenes with ethyl diazoacetate: an efficient one-pot synthesis of ethyl 3,4-dihydrochromeno[3,4-c]pyrazole-1-carboxylates	3
A method for the synthesis of 17-pyrimidinylandrostane	3
A new approach to the synthesis of 17-pyrazolylandrostane	3
New 13-vinyl derivatives of berberine: synthesis and characterization	3
Synthesis of new polycyclic compounds via the reaction of quinoline-8-sulfenyl halides with cyclic alkenes	3
Synthesis and antimicrobial evaluation of novel polyheterocyclic systems derived from cyclopenta[4',5']pyrido[3',2':4,5]furo[3,2-d]pyrimidine	3
Selenophenochromones Selectively Inhibit Human Lung Carcinoma Cells Growth	3
Selenium-containing azoles: synthesis and possibilities of application	3
Synthesis of 1,4-dihydro-1,2,4-benzotriazin-4-yl radicals (microreview)	3
Prediction of the regioselectivity of the ruthenium-catalyzed [3+2] cycloadditions of benzyl azide with internal alkynes using conceptual DFT indices of reactivity	3
[2+1] Cycloaddition reaction of α-atlantone with m-CPBA in the light of experimental and MEDT quantum-chemical study	3
Synthesis of heterocyclic compounds containing the 3,3-dicyanoacrylamide fragment	3
5(4)-Aminopyrazoles as effective reagents in the synthesis of pyrazolo-annulated pyridines	3
Synthesis of 5-azolyl-2,4-dihydro-3H-1,2,4-triazole-3-thiones and 5-azolyl-1,3,4-thiadiazol-2-amines based on derivatives of 5-arylisoxazole-3-carboxylic and 4,5-dichloroisothiazole-3-carboxylic acids	3
Toward unsymmetrical 2,6-bistriazolylpurine nucleosides	3
Synthesis of 2-triazolylpurine Phosphonates	3
Acenaphthenequinone-Based Stabilized Azomethine Ylides in (3+2) Cycloaddition Reactions with 1,5-diarylpent-4-ene-1,3-diones	3
Recent progress in the direct phosphorylation of parent heterocycles to construct phosphorylated heterocycles	3
Reactions of Quinolinecarbaldehydes with Arenes under Superelectrophilic Activation. NMR and DFT Studies of Dicationic Electrophilic Species	3
1,5-Diarylpent-4-ene-1,3-diones in the synthesis of spiro[(thia)pyrrolizidine-3,3'-oxindoles] and 1,3-diaryl-5-spiro[oxindole-3,3'-pyrrolizidin-2'-yl]-1H-pyrazoles	3
Methods of synthesis of 2-aminochromanes	3
Synthesis of Alkaloid Sinomenine Derivatives Containing a Pyrimidine Substituent in Ring A	3
Synthesis of 1,3-dialkyl-4-[(arylmethylidene)amino]glycolurils	3
A MEDT study of the mechanism and selectivity of the hetero-Diels–Alder reaction between 3-benzoylpyrrolo[1,2-c][1,4]-benzoxazine-1,2,4-trione and vinyl acetate	3
The synthesis of ortho-stilbazoles (2-styrylpyridines) (microreview)	3
Addition reaction of various azoles to perfluoromethyl vinyl ether	3
Photo- and ionochromic diarylethenes containing tetrazolo[1,5-a]quinoline receptor groups in a thiazole bridge and their application in test strips	3

Synthesis and properties of heterocycle-containing podands	3
Spiro Derivatives of 1,10b-dihydro-5H-pyrazolo[1,5-c][1,3]-benzoxazines and their Antimicrobial, Anti-Inflammatory, and Antioxidant Activity	3
Electrophilically activated nitroalkanes in the synthesis of substituted 1,3,4-oxadiazoles from amino acid derivatives	3
Synthesis of Monosubstituted Trifluoromethylated Derivatives of 2H-thiete, Dihydrothiophenes, and 2H-thiopyrans	3
Synthetic Methods toward Phosphacoumarins (microreview)	3
Synthesis of isoxazolo[5,4-b]pyridine derivatives (microreview)	3
In silico Study of Conjugated Nitrogen Heterocycles Affinity in their Biological Complexes	3
Synthesis and structure of 3-substituted 1,5-dinitro-1,3,5-triazepanes	3
Synthesis of 4-Ethoxycarbonyl(cyano)-β-Carbolines via Thermolysis of 4-Aryl-3(5)-Azidopyridine Derivatives and the Study of their Optical and Hypoglycemic Properties	3
4,5-Dihydro-1,2,4-triazin-6(1H)-ones (microreview)	3
Synthesis of Isoxazolylvinyl Ketones from Substituted Furans	3
[3-(Dimethylamino)-2-(trifluoromethyl)prop-2-en-1-ylidene]dimethylazanium hexafluorophosphate – efficient reagent for the formation of trifluoromethyl-substituted azaheterocycles (microreview)	3